CN105381096A - Medicine for treating acne caused by heat toxicity - Google Patents

Medicine for treating acne caused by heat toxicity Download PDF

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CN105381096A
CN105381096A CN201510995545.5A CN201510995545A CN105381096A CN 105381096 A CN105381096 A CN 105381096A CN 201510995545 A CN201510995545 A CN 201510995545A CN 105381096 A CN105381096 A CN 105381096A
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parts
medicine
radix
heat
treatment
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陈雯雯
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention discloses medicine for treating acne caused by heat toxicity. The medicine is mainly prepared from, by weight, 6-10 parts of coptis chinensis, 8-10 parts of radix scutellariae, 12-18 parts of cortex phellodendri, 8-12 parts of mint, 8-12 parts of folium mori, 6-10 parts of periostracum cicada, 12-18 parts of wild chrysanthemum flowers, 12-18 parts of honeysuckle, 6-10 parts of folium istatidis, 8-12 parts of dandelions, 6-10 parts of radix salviae miltiorrhizae, 8-12 parts of salivia chinensis, 6-10 parts of radix paeoniae rubra, 8-12 parts of rheum officinale and 4-6 parts of liquorice. According to the medicine used for treating the acne caused by the heat toxicity, fifteen kinds of natural traditional Chinese medicine are selected for scientific compatibility, the formula is simple, all the bulk drugs have the synergistic effect to achieve the effects of clearing away heat and toxic materials and activating blood to remove stasis, the medicine takes effect fast, treats both symptoms and root causes and is free of toxic and side effects, the preparing method is simple, the medicine is convenient to take, cost is low, and the effective rate is 97.5% or above.

Description

Be used for the treatment of the medicine of the comedo caused by pyretic toxicity
Technical field
The present invention relates to Chinese medicine, specifically a kind of medicine being used for the treatment of the comedo caused by pyretic toxicity.
Background technology
Comedo, is also acne, acne, skin sore, is dermatology common disease, frequently-occurring disease.Mainly be apt to occur in teenager, have 95% at Adolescent male, women has 85% to suffer from acne in various degree, so everybody is called " comedo " is very proper.Very large to teen-age psychology and social influence, but often can naturally alleviate or fully recover after adolescence.Comedo is that one betides pilosebaceous chronic dermatosis, is mainly in Head And Face, cervical region, the position that the sebaceous gland such as shirtfront back are abundant.The factors such as the generation of acne is main and hypersteatosis, pilosebaceous duct block, bacteriological infection and inflammatory reaction are closely related.After adolescing, in human body, the level of androgen particularly testosterone raises rapidly, promotes that sebaceous gland is grown and produces a large amount of sebum.The dyskeratosis of pilosebaceous duct causes catheter blockage, dyssebacia simultaneously, forms horn plug and micropowder thorn.Multiple-microorganism especially propionibacterium acnes amount reproduction in hair follicle, the lipase decomposition sebum that propionibacterium acnes produces generates free fatty, chemotactic inflammatory cell and medium simultaneously, final induction also exacerbate inflammation reaction.
Skin lesion is apt to occur in face and upper chest and back.The non-inflammation skin lesion of acne shows as opening and closed comedones.The typical skin lesion of closed comedones (also known as hoary hair) is the colour of skin pimple of about 1 mm in size, without obvious hair follicle opening.Open comedones (also known as blackhead) shows as the hair follicle opening that dome-shaped pimple companion significantly expands.Acne further develop and can develop into various struvite skin lesion, show as inflamed papules, pustule, tuberosity and cyst.Inflamed papules takes on a red color, and diameter 1 ~ 5 millimeter is not etc.; Pustule is in the same size, is wherein filled with white pus; Tuberosity diameter is greater than 5 millimeters, and that touches has scleroma and pain; The position of cyst is darker, is filled with the mixture of pus and blood.These skin lesion also can merge and form large inflammatory speckle and sinus tract etc.Pigmentation, erythema perstans, pitting or hypertrophic cicatrix is usually left over after struvite skin lesion disappears.Temporary pigmented spots can be left after acne disappears, or little hole concavity cicatrix.
The comedo caused by pyretic toxicity is many by scorching on accumulated heat in the lung and stomach, and the extraneous poison of multiple sense is evil, and pyretic toxicity is tied mutually, accumulates and causes in skin of face.Its disease is that face is dispersed in pimple, based on pimple, often has blush, conscious pain around, can be fiery glad bitterly red and swollen time serious, and with heating, red tongue tongue is dry, forceful pulse number etc.
Present is main mainly with western medicine, but effect is comparatively slow, and its side effect is large, can cause other diseases.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, and curative effect is not remarkable.
Summary of the invention
The object of this invention is to provide a kind of good effect, the medicine of comedo that short treating period, cost treatment that is low, that have no side effect are caused by pyretic toxicity.
The technical scheme realizing the object of the invention is:
Be used for the treatment of a medicine for the comedo caused by pyretic toxicity, the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 6-10 part, Radix Scutellariae 8-10 part, Cortex Phellodendri 12-18 part, Herba Menthae 8-12 part, Folium Mori 8-12 part, Periostracum Cicadae 6-10 part, Flos Chrysanthemi Indici 12-18 part, Flos Lonicerae 12-18 part, Folium Isatidis 6-10 part, Herba Taraxaci 8-12 part, Radix Salviae Miltiorrhizae 6-10 part, Cortex Moutan 8-12 part, Radix Paeoniae Rubra 6-10 part, Radix Et Rhizoma Rhei 8-12 part, Radix Glycyrrhizae 4-6 part.
The above-mentioned medicine being used for the treatment of the comedo caused by pyretic toxicity, optimum weight part proportioning of each raw material is:
Rhizoma Coptidis 8 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 15 parts, Herba Menthae 10 parts, 10 parts, Folium Mori, Periostracum Cicadae 8 parts, Flos Chrysanthemi Indici 15 parts, Flos Lonicerae 15 parts, Folium Isatidis 8 parts, Herba Taraxaci 10 parts, Radix Salviae Miltiorrhizae 8 parts, Cortex Moutan 10 parts, Radix Paeoniae Rubra 8 parts, Radix Et Rhizoma Rhei 10 parts, 5 parts, Radix Glycyrrhizae.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 30-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.Damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, and carbuncle treats skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.
Radix Scutellariae: have heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.
Cortex Phellodendri: have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.
Herba Menthae: dispelling wind and heat pathogens, the clear sharp head, sore-throat relieving rash, soothing the liver circulation of qi promoting.Affection due to external wind and heat, headache, laryngopharynx swelling and pain, dyspepsia flatulence, aphtha, toothache, skin ulcer scabies, urticaria, epidemic febrile disease from the beginning of, rubella pruritus, stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest.
Folium Mori: dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, suppressing the hyperactive liver improving eyesight, cooling blood for hemostasis.Anemopyretic cold, epidemic febrile disease from the beginning of, cough due to lung-heat, excessive rising of liver-YANG is dizzy, and conjunctival congestion is dim-sighted, the hemoptysis of bleeding due to blood-heat, haematemesis.
Periostracum Cicadae: dispelling wind and heat pathogens, relieving sore throat to recover voice, rash, improving acuity of vision and removing nebula, endogenous wind stopping relieving convulsion.For anemopyretic cold, epidemic febrile disease is from the beginning of, pharyngalgia hoarseness, and measles without adequate eruption, rubella pruritus, cataract, anxious chronic infantile convulsion, tetanus is demonstrate,proved, and the nocturnal fretfulness in infants is uneasy.
Flos Chrysanthemi Indici: tool dispelling wind and heat pathogens, subduing swelling and detoxicating.Furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis can be treated, the disease such as dizzy of having a headache.
Flos Lonicerae: can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain.
Folium Isatidis: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.For the high hot excessive thirst of calentura; Coma; Macule; Spit blood; Epistaxis; Jaundice; Dysentery; Erysipelas; Sore throat; Aphtha; Mumps.
Herba Taraxaci: heat-clearing and toxic substances removing, diuresis eliminating stagnation.Control acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis, hepatitis, cholecystitis, urinary tract infection.
Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Cortex Moutan: clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The pathogenic bacteria later stage brimful of tears, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and flutter the pain of injury; Beriberoid pyretic arthralgia.
Radix Paeoniae Rubra: clearing away heat and cooling blood, eliminating stasis to stop pain.For thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Radix Et Rhizoma Rhei: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.
Radix Glycyrrhizae: there is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The present invention is used for the treatment of the medicine of the comedo caused by pyretic toxicity, choose 15 kinds of natural Chinese medicine scientific compatibility, formula is simple, each crude drug synergism plays heat-clearing and toxic substances removing, the effect of promoting blood circulation to remove blood stasis, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
Be used for the treatment of a medicine for the comedo caused by pyretic toxicity, the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 6kg, Radix Scutellariae 8kg, Cortex Phellodendri 12kg, Herba Menthae 8kg, Folium Mori 8kg, Periostracum Cicadae 6kg, Flos Chrysanthemi Indici 12kg, Flos Lonicerae 12kg, Folium Isatidis 6kg, Herba Taraxaci 8kg, Radix Salviae Miltiorrhizae 6kg, Cortex Moutan 8kg, Radix Paeoniae Rubra 6kg, Radix Et Rhizoma Rhei 8kg, Radix Glycyrrhizae 4kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 30min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.10 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.
Embodiment 2
Be used for the treatment of a medicine for the comedo caused by pyretic toxicity, the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 8kg, Radix Scutellariae 10kg, Cortex Phellodendri 15kg, Herba Menthae 10kg, Folium Mori 10kg, Periostracum Cicadae 8kg, Flos Chrysanthemi Indici 15kg, Flos Lonicerae 15kg, Folium Isatidis 8kg, Herba Taraxaci 10kg, Radix Salviae Miltiorrhizae 8kg, Cortex Moutan 10kg, Radix Paeoniae Rubra 8kg, Radix Et Rhizoma Rhei 10kg, Radix Glycyrrhizae 5kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 15 times, decoct 34min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 53 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 3
Be used for the treatment of a medicine for the comedo caused by pyretic toxicity, the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 10kg, Radix Scutellariae 10kg, Cortex Phellodendri 18kg, Herba Menthae 12kg, Folium Mori 12kg, Periostracum Cicadae 10kg, Flos Chrysanthemi Indici 18kg, Flos Lonicerae 18kg, Folium Isatidis 10kg, Herba Taraxaci 12kg, Radix Salviae Miltiorrhizae 10kg, Cortex Moutan 12kg, Radix Paeoniae Rubra 10kg, Radix Et Rhizoma Rhei 12kg, Radix Glycyrrhizae 6kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 37min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 57 DEG C, add adjuvant, make pill, every 0.4g.
Embodiment 4
Be used for the treatment of a medicine for the comedo caused by pyretic toxicity, the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 10kg, Radix Scutellariae 10kg, Cortex Phellodendri 18kg, Herba Menthae 12kg, Folium Mori 12kg, Periostracum Cicadae 10kg, Flos Chrysanthemi Indici 18kg, Flos Lonicerae 18kg, Folium Isatidis 10kg, Herba Taraxaci 12kg, Radix Salviae Miltiorrhizae 10kg, Cortex Moutan 12kg, Radix Paeoniae Rubra 10kg, Radix Et Rhizoma Rhei 12kg, Radix Glycyrrhizae 6kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 400 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 15-35 year, be divided into 4 groups at random, often group be 100 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 2 times, each 3 slices/for oral administration, within 10 days, is a course for the treatment of, takes 1-2 the course for the treatment of continuously, add and subtract the course for the treatment of depending on state of an illness weight.Wherein effective 387 examples, effective 385 examples, cure 390 examples, invalid 10 examples, cure rate 96%, effective percentage 97.5%.

Claims (3)

1. be used for the treatment of a medicine for the comedo caused by pyretic toxicity, it is characterized in that: the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 6-10 part, Radix Scutellariae 8-10 part, Cortex Phellodendri 12-18 part, Herba Menthae 8-12 part, Folium Mori 8-12 part, Periostracum Cicadae 6-10 part, Flos Chrysanthemi Indici 12-18 part, Flos Lonicerae 12-18 part, Folium Isatidis 6-10 part, Herba Taraxaci 8-12 part, Radix Salviae Miltiorrhizae 6-10 part, Cortex Moutan 8-12 part, Radix Paeoniae Rubra 6-10 part, Radix Et Rhizoma Rhei 8-12 part, Radix Glycyrrhizae 4-6 part.
2. the medicine being used for the treatment of the comedo caused by pyretic toxicity according to claim 1, is characterized in that: optimum weight part proportioning of each raw material is:
Rhizoma Coptidis 8 parts, Radix Scutellariae 10 parts, Cortex Phellodendri 15 parts, Herba Menthae 10 parts, 10 parts, Folium Mori, Periostracum Cicadae 8 parts, Flos Chrysanthemi Indici 15 parts, Flos Lonicerae 15 parts, Folium Isatidis 8 parts, Herba Taraxaci 10 parts, Radix Salviae Miltiorrhizae 8 parts, Cortex Moutan 10 parts, Radix Paeoniae Rubra 8 parts, Radix Et Rhizoma Rhei 10 parts, 5 parts, Radix Glycyrrhizae.
3. the medicine being used for the treatment of the comedo caused by pyretic toxicity according to claim 1, is characterized in that:
Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 30-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.10-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
CN201510995545.5A 2015-12-28 2015-12-28 Medicine for treating acne caused by heat toxicity Pending CN105381096A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177222A (en) * 2016-08-22 2016-12-07 黄琴 For treating the medicine of acne
CN108295159A (en) * 2018-03-23 2018-07-20 王滋东 A kind of topical agent for treating whelk
CN116077388A (en) * 2022-11-29 2023-05-09 山东禾宝药业有限公司 Acne-removing Chinese herbal medicine composition and preparation method and application thereof

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CN102078450A (en) * 2009-12-01 2011-06-01 王小华 Pharmaceutical composition for treating whelk

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Publication number Priority date Publication date Assignee Title
CN102078450A (en) * 2009-12-01 2011-06-01 王小华 Pharmaceutical composition for treating whelk

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106177222A (en) * 2016-08-22 2016-12-07 黄琴 For treating the medicine of acne
CN108295159A (en) * 2018-03-23 2018-07-20 王滋东 A kind of topical agent for treating whelk
CN116077388A (en) * 2022-11-29 2023-05-09 山东禾宝药业有限公司 Acne-removing Chinese herbal medicine composition and preparation method and application thereof

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