CN104984147A - Traditional Chinese medicinal tablet for treating infant scalp folliculitis, and preparation method thereof - Google Patents
Traditional Chinese medicinal tablet for treating infant scalp folliculitis, and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal tablet for treating infant scalp folliculitis, and a preparation method thereof. The traditional Chinese medicinal tablet is prepared from, by weight, 6-9 parts of sophora flavescens, 5-10 parts of Lighiyellow Sophora Root, 15-20 parts of onion, 5-8 parts of runcinate knotweed root, 7-10 parts of laxflower pottsia root, 9-12 parts of Rhizoma Coptidis, 9-12 parts of Radix Scutellariae, 6-8 parts of Bark of Japanese Pagodatree, 7-9 parts of Achillea sibirca, 8-10 parts of Leaf of Chinese Pearleaf Crabapple, 5-7 parts of pomegranate rind, 10-15 parts of purslane, 6-8 parts of Carpinus cordata B1.var.chinensis Franch., 20-25 parts of quails, 20-30 parts of wheat, 9-11 parts of Bletilla striata, 4-6 parts of Trillium tschonoskii Maxim., 8-10 parts of honey-fried licorice root and 6-8 parts of periostracum cicadae. The tablet is a pure traditional Chinese medicinal preparation, avoids abuses of western medicine treatment, is safe, has no toxic side effects, realizes internal treatment of external diseases, adjusts the body of infant patients while effectively killing pathogenic bacteria, fundamentally treat the infant scalp folliculitis, and also has the advantages of substantial curative effect and difficult recurrence.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind ofly treat Chinese medicinal tablet of children scalp folliculitis and preparation method thereof and preparation method thereof.
Background technology
Scalp hair follicles inflammation is that a kind of inflammatory that pyococcus is invaded around follicular orifice changes, and folliculitis, from the beginning of being red lex primaria pimple, develops into papular abscess rapidly later, and inflammation is just called scalp hair follicles in head.Primary disease is more common in immunocompromised person or diabetics, and folliculitis, from the beginning of being red lex primaria pimple, develops into papular abscess rapidly later, then dry, incrustation, leaves no trace after crust is de-.Erythra number is many, but does not merge.Folliculitis is mainly in adult, and in general the site of pathological change of folliculitis is all at head, shank, upper arm, the position that pudendum hair follicle is many.Children's's morbidity of hypoimmunity then can be many at head, i.e. children scalp folliculitis.The treatment of doctor trained in Western medicine to children scalp folliculitis adopts antibiotherapy more, and antibiotic therapy is long for the course for the treatment of, brings heavy burden that is economic and two aspects at heart easily to patient and family members.And antibiotic therapy easily produces drug resistance, and destroy child's autoimmunity, cause Relapse rate to show effect.Meanwhile, luxuriant hair adds the incompatibility in the middle of to child for treatment, and add difficulty also to the treatment of folliculitis, antibiotic therapy is long for the course for the treatment of, brings heavy burden that is economic and two aspects at heart easily to patient and family members.
Motherland's theory of medicine is thought, folliculitis is many by retention of damp-heat in the interior, outward by pathogenic heat, and then stifling lung system, pent up skin and send out.The strongly fragrant heat-transformation of a specified duration of evil poison, the corruption of intenseness of heat meat then becomes pus, and septicopyemia is fled, mutually through, sends out as folliculitis.Or because of ferritic weakness, weakened defensive QI, diseases caused by exogenous pathogenic factor pyretic toxicity; Or because of skin unclean, attacked by pathogenic wind toxic, fight outside wind knot and cause.In view of many drawbacks of western medical treatment, adopt tcm therapy treatment folliculitis, especially children scalp folliculitis becomes comparatively ideal treatment means.
Summary of the invention
The present invention according to traditional Chinese medical science Synergy, for a kind of cause of disease for the treatment of folliculitis, with the characteristic of children population hypoimmunity, from entirety, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, provides a kind of and treats Chinese medicinal tablet of children scalp folliculitis and preparation method thereof, this tablet adopts pure Chinese medicinal preparation, avoid the drawback of western medical treatment, safe without toxic side effect, outer sick treatment by oral administration of medicines, while effectively killing pathogenic bacterium, regulate children patient, fundamentally treat this disease, evident in efficacy and not easily recur.
To achieve these goals, technical scheme provided by the invention is as follows:
A kind of Chinese medicinal tablet for the treatment of children scalp folliculitis, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 6-9 part, Radix sophorae 5-10 part, Bulbus Allii Cepae 15-20 part, Radix Polygoni Runcinati 5-8 part, Radix Pottsiae Laxiflorae 7-10 part, Rhizoma Coptidis 9-12 part, Radix Scutellariae 9-12 part, Cortex sophorae 6-8 part, achillea millefolium 7-9 part, Folium Mali Asiaticae 8-10 part, Pericarpium Granati 5-7 part, Herba Portulacae 10-15 part, China carpinus turczaninowii 6-8 part, Carnis Coturnicis japonicae 20-25 part, Semen Tritici aestivi 20-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9-11 part, Rhizoma Trillii Tschonoskii 4-6 part, Radix Glycyrrhizae Preparata 8-10 part, Periostracum Cicadae 6-8 part.
Further, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 6 parts, Radix sophorae 5 parts, Bulbus Allii Cepae 15 parts, Radix Polygoni Runcinati 5 parts, Radix Pottsiae Laxiflorae 7 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 9 parts, Cortex sophorae 6 parts, achillea millefolium 7 parts, Folium Mali Asiaticae 8 parts, Pericarpium Granati 5 parts, Herba Portulacae 10 parts, magnificent carpinus turczaninowii 6 parts, Carnis Coturnicis japonicae 20 parts, Semen Tritici aestivi 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, Rhizoma Trillii Tschonoskii 4 parts, Radix Glycyrrhizae Preparata 8 parts, Periostracum Cicadae 6 parts.
Further, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 9 parts, Radix sophorae 10 parts, Bulbus Allii Cepae 20 parts, Radix Polygoni Runcinati 8 parts, Radix Pottsiae Laxiflorae 10 parts, Rhizoma Coptidis 12 parts, Radix Scutellariae 12 parts, Cortex sophorae 8 parts, achillea millefolium 9 parts, Folium Mali Asiaticae 10 parts, Pericarpium Granati 7 parts, Herba Portulacae 15 parts, magnificent carpinus turczaninowii 8 parts, Carnis Coturnicis japonicae 25 parts, Semen Tritici aestivi 30 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 11 parts, Rhizoma Trillii Tschonoskii 6 parts, Radix Glycyrrhizae Preparata 10 parts, Periostracum Cicadae 8 parts.
Further, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 8 parts, Radix sophorae 7 parts, Bulbus Allii Cepae 17 parts, Radix Polygoni Runcinati 6 parts, Radix Pottsiae Laxiflorae 8 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 11 parts, Cortex sophorae 7 parts, achillea millefolium 8 parts, Folium Mali Asiaticae 9 parts, Pericarpium Granati 6 parts, Herba Portulacae 12 parts, magnificent carpinus turczaninowii 7 parts, Carnis Coturnicis japonicae 22 parts, Semen Tritici aestivi 23 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Rhizoma Trillii Tschonoskii 5 parts, Radix Glycyrrhizae Preparata 9 parts, Periostracum Cicadae 7 parts.
The invention also discloses the preparation method of the Chinese medicinal tablet of described treatment children scalp folliculitis, comprise the following steps:
(1) Carnis Coturnicis japonicae unhairing is cut into small pieces after going internal organs to clean, and adds the distilled water of its mass fraction 20 times, decocts 45 minutes at 110 DEG C, and cross 1000 order drainage screens, gained filtrate is for subsequent use, and gained Carnis Coturnicis japonicae block is boned and stayed meat for subsequent use;
(2) Semen Tritici aestivi is cleaned, and puts into steamer 120 DEG C of steaming and decoctings 20 minutes, and the Semen Tritici aestivi cooked mixes with step 1 gained quail meat to be put into 80 DEG C, baking oven and dry 60 minutes, and gained drying composite super micron mill is pulverized, and mistake 500 mesh sieves obtain powder;
(3) Radix Sophorae Flavescentis, Radix sophorae, Radix Polygoni Runcinati, Radix Pottsiae Laxiflorae, Rhizoma Coptidis, Radix Scutellariae, Cortex sophorae, achillea millefolium, Folium Mali Asiaticae, Pericarpium Granati, magnificent carpinus turczaninowii, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Trillii Tschonoskii, Radix Glycyrrhizae Preparata, Periostracum Cicadae are pulverized, and cross 50 mesh sieves and obtain coarse powder, for subsequent use;
(4) step (3) gained coarse powder adds step 1 gained filtrate, and soak 1 hour, slow fire boiling 1 hour, decocting liquid crosses 1000 order drainage screens, and gained filtrate is dried in the air cool to room temperature, for subsequent use;
(5) Bulbus Allii Cepae, Herba Portulacae are smash juice after cleaning, then cross 1000 order mesh screens, collect filtered juice;
(6) step (4) gained filtrate mixed homogeneously with step (5) gained filtered juice, cross 1000 filter screen filtration, gained filter vacuum is concentrated into the thick paste that relative density is 1.30 ± 0.02 (60 DEG C);
(7) add in thick paste obtained in step (6) by powder obtained in step (2), stirring and evenly mixing, granulate, granulate, tabletting is made sheet and is weighed the tablet of 0.5 gram and get final product.
Folliculitis is many by retention of damp-heat in the interior, outward by pathogenic heat, and then stifling lung system, pent up skin and send out.The strongly fragrant heat-transformation of a specified duration of evil poison, the corruption of intenseness of heat meat then becomes pus, and septicopyemia is fled, mutually through, sends out as folliculitis.Chinese medicinal tablet of the present invention is according to the pathological characteristic of this disease, take dampness debug, anti-inflammation, detumescence and promoting granulation, invigorating the spleen and replenishing QI method treat this disease, according to Chinese medical theory determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, raw material of Chinese medicine is screened by great many of experiments, refining agent method, make each efficacy of drugs produce synergism, thus reach the effect for the treatment of both the principal and secondary aspects of a disease.In the crude drug chosen: Radix Sophorae Flavescentis: bitter in the mouth, cold in nature, heat clearing and damp drying, parasite killing, diuresis, for hematodiarrhoea, has blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis, Radix sophorae: bitter in the mouth, property is put down, dissipating blood stasis for subsidence of swelling, parasite killing, main hemorrhoid, sore throat, ascariasis, Bulbus Allii Cepae: containing phytocide as garlicin etc., there is very strong sterilizing ability, can effectively resist influenza virus, preventing cold, when this phytocide is discharged via respiratory tract, urinary tract, sweat gland, the cell duct wall of these positions can be stimulated to secrete, thus eliminate the phlegm again, diuresis, diaphoresis and the antibacterial effect such as anticorrosion, Radix Polygoni Runcinati: cold in nature, bitter in the mouth is micro-puckery, controls hemorrhoid, nine sub-infectionss, for traumatic injury, relaxing muscles and tendons to promote blood circulation, synthetism, the wound that disappears is swollen, only grieved, Radix Pottsiae Laxiflorae: bitter, pungent, slightly warm in nature, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, main air pain of dampness syndrome, traumatic injury, women's amenorrhea, Rhizoma Coptidis: bitter in the mouth, cold, heat clearing and damp drying, eliminating fire and detoxication, anti-inflammation, for damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, toothache, quench one's thirst, carbuncle furuncle, external treatment eczema, eczema, auditory meatus is suppurated, it is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs, for conjunctival congestion, aphtha, prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting, tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted, cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting, for incoordination between the liver and stomach, vomiting acid regurgitation, Rhizoma Coptidis and Radix Glycyrrhizae are share can the effect of obvious its anti-Staphylococcus aureus of gain, Radix Scutellariae: bitter in the mouth, cold in nature, there are heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive, cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle, the clinical antibiotic property of Radix Scutellariae is better than Rhizoma Coptidis, and does not develop immunity to drugs, Cortex sophorae: bitter, flat, expelling wind and removing dampness, reducing swelling and alleviating pain, controls in outside ailment said due to cold or exposure, orthotonus, numbness of the skin, calentura aphtha, ulcerative gingivitis, sore throat, discharging fresh blood stool, cellulitis, hemorrhoid, rotten skin ulcer, and pudendum is itched bitterly, soup, burning hot wound, achillea millefolium: bitter, acid, flat, anti-inflammation, removing toxic substances analgesia.With controlling mastitis, acute tonsillitis, appendicitis, pyelitis etc., rheumatalgia, traumatic injury, innominate toxic swelling, venom etc., have inhibitory action to staphylococcus aureus, dysentery bacterium, escherichia coli, bacillus pyocyaneus; Folium Mali Asiaticae: pungent, tepor, purging pathogenic fire and improving eyesight, parasite killing detoxifies, and dominant eye bluish eyes is blind, pterygium, children's's scabies; Pericarpium Granati: convergence, antibacterial, in vitro tests has antibacterial action to bacillus pyocyaneus, bacterium flexneri, Bacillus typhi, also has inhibitory action in various degree to various skin fungus.Also has resisiting influenza virus effect; Herba Portulacae: cold in nature, sweet in the mouth acid; Enter the heart, liver, spleen, large intestine channel.Have that removing dampness is antipruritic, clearing heat for detumescence, heat-clearing and toxic substances removing, diuretic dries, loose blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, the effect of hemostasis removing heat from blood.Herba Portulacae has stronger inhibitory action to dysentery bacterium, Bacillus typhi and escherichia coli, can be used for the auxiliary treatment of various inflammation, have the title of " natural antibiotics ", simultaneously Herba Portulacae is also rich in vitamin C, and vitamin C has good antioxidation can whitening nourishes rough skin; China carpinus turczaninowii: light, property is put down, promoting blood circulation and detumescence, and dampness removing is treating stranguria, main traumatic injury, carbuncle sore tumefacting virus, stranguria; Carnis Coturnicis japonicae: sweet in the mouth, property is put down, and has tonifying five ZANG-organs, gas in benefit, the merit of eliminating damp-heat.For malnutrition, asthenia is thin and weak, chronic diarrhea chronic dysentery, the diseases such as inappetence; Semen Tritici aestivi: sweet in the mouth, cool in nature, there is invigorating spleen and nourishing heart kidney tonifying, the merit that heat extraction quenches the thirst, for dry mouth and throat, dysphoria, inappetence etc.; Pseudobulbus Bletillae (Rhizoma Bletillae): bitter in the mouth, sweet, puckery, cold in nature, returns lung, liver, stomach warp, has astringing to arrest bleeding, the merit of detumescence and promoting granulation, for all cards of interior external haemorrhage and carbuncle, scald, rhagadia manus et pedis, anal fissure etc.; Rhizoma Trillii Tschonoskii: sweet in the mouth is micro-pungent, warm in nature, hemostasis, analgesia, granulation promoting, except rheumatism, detumescence poison, controls traumatic hemorrhage, various lumbago, impairment caused by overstrain, traumatic injury, innominate toxic swelling; Radix Glycyrrhizae Preparata: containing number of chemical compositions such as glycyrrhizin, enoxolone, Angelica Polysaccharide, there is antiinflammatory and anti-allergy action, scalable body's immunity, antitumor and analgesic effect, therefore the primary efficacy of Radix Glycyrrhizae Preparata is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Periostracum Cicadae: sweet in the mouth, salty, cool in nature, dispelling wind and heat pathogens, relieving sore throat to recover voice, rash, improving acuity of vision and removing nebula, endogenous wind stopping relieving convulsion, can reach skin by priming.
In all medicines, Rhizoma Coptidis, Radix Sophorae Flavescentis are monarch drug, play the effect of dampness debug, anti-inflammation, for this this disease of sick etiological treatment.Radix sophorae, Bulbus Allii Cepae, Radix Polygoni Runcinati, Radix Pottsiae Laxiflorae, Radix Scutellariae, Cortex sophorae, achillea millefolium, Folium Mali Asiaticae, Pericarpium Granati, Herba Portulacae, magnificent carpinus turczaninowii, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Trillii Tschonoskii, Carnis Coturnicis japonicae, Blumeae preparatum Tabellae are ministerial drug; Wherein, Radix sophorae, Radix Pottsiae Laxiflorae, Cortex sophorae, Folium Mali Asiaticae, Rhizoma Trillii Tschonoskii can the effects of gain monarch drug dampness debug, remove ailment said due to cold or exposure pyretic toxicity, recover body health; Bulbus Allii Cepae, Radix Scutellariae, achillea millefolium, Pericarpium Granati, Herba Portulacae can the effect of gain monarch drug anti-inflammation, effectively kills pathogenic bacterium; Ministerial drug Radix sophorae, Radix Polygoni Runcinati, Cortex sophorae, magnificent carpinus turczaninowii, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Trillii Tschonoskii also can play the effect of detumescence and promoting granulation, eliminate affected part pustule, protection illing skin, promote that illing skin recovers; Semen Tritici aestivi, Carnis Coturnicis japonicae have the effect of invigorating the spleen and replenishing QI, effectively reduction of patient can to take medicine the body deficient syndrome shape caused, improve patient's autoimmunity, promote the performance of other drug effects, accelerate the rehabilitation of patient.Radix Glycyrrhizae Preparata is assistant, and Radix Glycyrrhizae Preparata plays harmonizing yingfen and weifen, the effect of warming spleen and stomach for dispelling cold, and meanwhile, Rhizoma Coptidis and Radix Glycyrrhizae are share can the effect of obvious its anti-Staphylococcus aureus of gain.Periostracum Cicadae, for drawing, can reach skin by priming, better treat dermatosis.Medicine of the present invention is pure Chinese medicinal preparation, and selected medical material compatibility is suitable, and adopts modern advanced medical pharmaceutical technology to make, and for this disease of cause of disease treatment for diseases, has treating both the principal and secondary aspects of a disease rapid-action, the remarkable advantage of safe without toxic side effect.
Beneficial effect of the present invention is: the invention provides and a kind ofly treat Chinese medicinal tablet of children scalp folliculitis and preparation method thereof, this tablet adopts pure Chinese medicinal preparation, selected medical material compatibility is suitable, and adopt modern advanced medical pharmaceutical technology to make, adopt dampness debug, anti-inflammation, detumescence and promoting granulation, the method of invigorating the spleen and replenishing QI, inner disease outer treat, regulate patient's body, improve patient's immunity, improve the system of child patient hypoimmunity, effectively kill pathogenic bacterium, this disease for the treatment of both the principal and secondary aspects of a disease, avoid the drawback of doctor trained in Western medicine antibiotic therapy, safe without toxic side effect, evident in efficacy, more not easily recur after.In formula, select the Semen Tritici aestivi of temperature compensation, effect that Carnis Coturnicis japonicae plays invigorating the spleen and replenishing QI, gentle conditioning children patient, strengthening infant immunity, alleviating the body deficient syndrome shape that infant causes because taking medicine for a long time, infant void is effectively avoided not cause by benefit symptom of getting angry, Radix Glycyrrhizae Preparata is assistant, and Radix Glycyrrhizae Preparata plays harmonizing yingfen and weifen, the effect of warming spleen and stomach for dispelling cold, meanwhile, Rhizoma Coptidis and Radix Glycyrrhizae share can the effect of obvious its anti-Staphylococcus aureus of gain.Periostracum Cicadae, for drawing, can reach skin by priming, better treat dermatosis.
Detailed description of the invention
According to following embodiment, the present invention may be better understood.But those skilled in the art will readily understand, concrete material proportion, process conditions and result thereof described by embodiment only should can not limit the present invention described in detail in claims yet for illustration of the present invention.
Embodiment 1
Treat a Chinese medicinal tablet for children scalp folliculitis, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 6 parts, Radix sophorae 5 parts, Bulbus Allii Cepae 15 parts, Radix Polygoni Runcinati 5 parts, Radix Pottsiae Laxiflorae 7 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 9 parts, Cortex sophorae 6 parts, achillea millefolium 7 parts, Folium Mali Asiaticae 8 parts, Pericarpium Granati 5 parts, Herba Portulacae 10 parts, magnificent carpinus turczaninowii 6 parts, Carnis Coturnicis japonicae 20 parts, Semen Tritici aestivi 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, Rhizoma Trillii Tschonoskii 4 parts, Radix Glycyrrhizae Preparata 8 parts, Periostracum Cicadae 6 parts.
The preparation method of the Chinese medicinal tablet of described treatment children scalp folliculitis, comprises the following steps:
(1) Carnis Coturnicis japonicae unhairing is cut into small pieces after going internal organs to clean, and adds the distilled water of its mass fraction 20 times, decocts 45 minutes at 110 DEG C, and cross 1000 order drainage screens, gained filtrate is for subsequent use, and gained Carnis Coturnicis japonicae block is boned and stayed meat for subsequent use;
(2) Semen Tritici aestivi is cleaned, and puts into steamer 120 DEG C of steaming and decoctings 20 minutes, and the Semen Tritici aestivi cooked mixes with step 1 gained quail meat to be put into 80 DEG C, baking oven and dry 60 minutes, and gained drying composite super micron mill is pulverized, and mistake 500 mesh sieves obtain powder;
(3) Radix Sophorae Flavescentis, Radix sophorae, Radix Polygoni Runcinati, Radix Pottsiae Laxiflorae, Rhizoma Coptidis, Radix Scutellariae, Cortex sophorae, achillea millefolium, Folium Mali Asiaticae, Pericarpium Granati, magnificent carpinus turczaninowii, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Trillii Tschonoskii, Radix Glycyrrhizae Preparata, Periostracum Cicadae are pulverized, and cross 50 mesh sieves and obtain coarse powder, for subsequent use;
(4) step (3) gained coarse powder adds step 1 gained filtrate, and soak 1 hour, slow fire boiling 1 hour, decocting liquid crosses 1000 order drainage screens, and gained filtrate is dried in the air cool to room temperature, for subsequent use;
(5) Bulbus Allii Cepae, Herba Portulacae are smash juice after cleaning, then cross 1000 order mesh screens, collect filtered juice;
(6) step (4) gained filtrate mixed homogeneously with step (5) gained filtered juice, cross 1000 filter screen filtration, gained filter vacuum is concentrated into the thick paste that relative density is 1.30 ± 0.02 (60 DEG C);
(7) add in thick paste obtained in step (6) by powder obtained in step (2), stirring and evenly mixing, granulate, granulate, tabletting is made sheet and is weighed the tablet of 0.5 gram and get final product.
Usage and dosage: three times on the oral one, one time 6
Embodiment 2
Treat a Chinese medicinal tablet for children scalp folliculitis, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 9 parts, Radix sophorae 10 parts, Bulbus Allii Cepae 20 parts, Radix Polygoni Runcinati 8 parts, Radix Pottsiae Laxiflorae 10 parts, Rhizoma Coptidis 12 parts, Radix Scutellariae 12 parts, Cortex sophorae 8 parts, achillea millefolium 9 parts, Folium Mali Asiaticae 10 parts, Pericarpium Granati 7 parts, Herba Portulacae 15 parts, magnificent carpinus turczaninowii 8 parts, Carnis Coturnicis japonicae 25 parts, Semen Tritici aestivi 30 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 11 parts, Rhizoma Trillii Tschonoskii 6 parts, Radix Glycyrrhizae Preparata 10 parts, Periostracum Cicadae 8 parts.
The preparation method of the Chinese medicinal tablet of embodiment 2 is identical with embodiment 1 with usage and dosage.
Embodiment 3
Treat a Chinese medicinal tablet for children scalp folliculitis, raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 8 parts, Radix sophorae 7 parts, Bulbus Allii Cepae 17 parts, Radix Polygoni Runcinati 6 parts, Radix Pottsiae Laxiflorae 8 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 11 parts, Cortex sophorae 7 parts, achillea millefolium 8 parts, Folium Mali Asiaticae 9 parts, Pericarpium Granati 6 parts, Herba Portulacae 12 parts, magnificent carpinus turczaninowii 7 parts, Carnis Coturnicis japonicae 22 parts, Semen Tritici aestivi 23 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Rhizoma Trillii Tschonoskii 5 parts, Radix Glycyrrhizae Preparata 9 parts, Periostracum Cicadae 7 parts.
The preparation method of the Chinese medicinal tablet of embodiment 3 is identical with embodiment 1 with usage and dosage.
Embodiment 4 toxicity test
NIH mice 40, SPF level, body weight 20 ~ 25g, carries out acute toxicity test.Mice is divided into four groups at random, often organizes 10, male and female half and half, i.e. matched group and 3 administration groups, fasting 12 hours before experiment; The tablet of embodiments of the invention 1 to 3 is dissolved in water respectively, (concentration is 3g crude drug/ml to give 3 administration group gavages respectively, maximum concentration), gavage volume is 10ml/kg (namely unit dosage form is crude drug 30/kg), matched group gives normal saline, administration in a day 3 times, delivery time 4 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage Chinese medicinal tablet LD50>30 crude drug/kg of the present invention, every day, maximum dosage-feeding was 90 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention be 9g crude drug/day/people, adult body weight in 60KG, average dosage is 0.15g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 22.5g) oral administration gavage tablet of the present invention is 600 times of quantity.Therefore Chinese medicinal tablet toxicity of the present invention is low, clinical drug safety.
Embodiment 5 clinical trial:
Random selecting 150 children scalp folliculitis patients carry out clinical experiment, and in children age 1-6 year, average 3.5 years old, using Chinese medicinal tablet of the present invention to treat this disease, 7th is a course for the treatment of, investigates the curative effect of Chinese medicinal tablet of the present invention, and the evaluation criterion of curative effect is:
Recovery from illness: skin lesion is formed a scab completely;
Effective: the incrustation of skin lesion major part;
Take a turn for the better: skin lesion part forms a scab, send out skin lesion without new;
Invalid: skin lesion is only formed a scab on a small quantity or still had new skin lesion or aggravation.
Experimental result can be found out, the effective percentage of Chinese medicinal tablet treatment children's folliculitis of the present invention can reach more than 98%, and all patients all had no adverse reaction in the medication stage.
Clinical model case:
Revive certain, female, 3.5 years old, started scalp and occur a large amount of red lex primaria pimple, be diagnosed as scalp hair follicles inflammation before ten days, after use neomycin ointment is smeared and failed to respond to any medical treatment, fully recover after using the Chinese medicinal tablet of the embodiment of the present invention 1 to treat 1 course for the treatment of, rear 3 months without recurrence.
Grandson, man, 4 years old, before January there is a large amount of red lex primaria pimple in scalp, develop into papular pustule gradually, the micro-pain of the conscious scalp itch of patient, is diagnosed as scalp hair follicles inflammation, after using the Chinese medicinal tablet of the embodiment of the present invention 2 to treat 1 course for the treatment of, the incrustation of skin lesion major part, scalp itch symptom disappears, and fully recovers after using 2 courses for the treatment of, and rear 3 months without recurrence.
Zhang, man, 3.5 years old, started scalp and occur a large amount of red lex primaria pimple, be diagnosed as scalp hair follicles inflammation before five days, fully recover after using the Chinese medicinal tablet of the embodiment of the present invention 3 to treat 1 course for the treatment of, rear 3 months without recurrence.
Above embodiment is only for illustrating technical conceive of the present invention and feature; its object is to allow person skilled in the art understand content of the present invention and to be implemented; can not limit the scope of the invention with this; all equivalences done according to spirit of the present invention change or modify, and all should be encompassed in protection scope of the present invention.
Claims (5)
1. treat the Chinese medicinal tablet of children scalp folliculitis for one kind, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 6-9 part, Radix sophorae 5-10 part, Bulbus Allii Cepae 15-20 part, Radix Polygoni Runcinati 5-8 part, Radix Pottsiae Laxiflorae 7-10 part, Rhizoma Coptidis 9-12 part, Radix Scutellariae 9-12 part, Cortex sophorae 6-8 part, achillea millefolium 7-9 part, Folium Mali Asiaticae 8-10 part, Pericarpium Granati 5-7 part, Herba Portulacae 10-15 part, China carpinus turczaninowii 6-8 part, Carnis Coturnicis japonicae 20-25 part, Semen Tritici aestivi 20-30 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 9-11 part, Rhizoma Trillii Tschonoskii 4-6 part, Radix Glycyrrhizae Preparata 8-10 part, Periostracum Cicadae 6-8 part.
2. a kind of Chinese medicinal tablet for the treatment of children scalp folliculitis as claimed in claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 6 parts, Radix sophorae 5 parts, Bulbus Allii Cepae 15 parts, Radix Polygoni Runcinati 5 parts, Radix Pottsiae Laxiflorae 7 parts, Rhizoma Coptidis 9 parts, Radix Scutellariae 9 parts, Cortex sophorae 6 parts, achillea millefolium 7 parts, Folium Mali Asiaticae 8 parts, Pericarpium Granati 5 parts, Herba Portulacae 10 parts, magnificent carpinus turczaninowii 6 parts, Carnis Coturnicis japonicae 20 parts, Semen Tritici aestivi 20 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 9 parts, Rhizoma Trillii Tschonoskii 4 parts, Radix Glycyrrhizae Preparata 8 parts, Periostracum Cicadae 6 parts.
3. a kind of Chinese medicinal tablet for the treatment of children scalp folliculitis as claimed in claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 9 parts, Radix sophorae 10 parts, Bulbus Allii Cepae 20 parts, Radix Polygoni Runcinati 8 parts, Radix Pottsiae Laxiflorae 10 parts, Rhizoma Coptidis 12 parts, Radix Scutellariae 12 parts, Cortex sophorae 8 parts, achillea millefolium 9 parts, Folium Mali Asiaticae 10 parts, Pericarpium Granati 7 parts, Herba Portulacae 15 parts, magnificent carpinus turczaninowii 8 parts, Carnis Coturnicis japonicae 25 parts, Semen Tritici aestivi 30 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 11 parts, Rhizoma Trillii Tschonoskii 6 parts, Radix Glycyrrhizae Preparata 10 parts, Periostracum Cicadae 8 parts.
4. a kind of Chinese medicinal tablet for the treatment of children scalp folliculitis as claimed in claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal tablet are: Radix Sophorae Flavescentis 8 parts, Radix sophorae 7 parts, Bulbus Allii Cepae 17 parts, Radix Polygoni Runcinati 6 parts, Radix Pottsiae Laxiflorae 8 parts, Rhizoma Coptidis 10 parts, Radix Scutellariae 11 parts, Cortex sophorae 7 parts, achillea millefolium 8 parts, Folium Mali Asiaticae 9 parts, Pericarpium Granati 6 parts, Herba Portulacae 12 parts, magnificent carpinus turczaninowii 7 parts, Carnis Coturnicis japonicae 22 parts, Semen Tritici aestivi 23 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts, Rhizoma Trillii Tschonoskii 5 parts, Radix Glycyrrhizae Preparata 9 parts, Periostracum Cicadae 7 parts.
5. a kind of preparation method for the treatment of the Chinese medicinal tablet of children scalp folliculitis as described in Claims 1-4, is characterized in that: comprise the following steps:
(1) Carnis Coturnicis japonicae unhairing is cut into small pieces after going internal organs to clean, and adds the distilled water of its mass fraction 20 times, decocts 45 minutes at 110 DEG C, and cross 1000 order drainage screens, gained filtrate is for subsequent use, and gained Carnis Coturnicis japonicae block is boned and stayed meat for subsequent use;
(2) Semen Tritici aestivi is cleaned, and puts into steamer 120 DEG C of steaming and decoctings 20 minutes, and the Semen Tritici aestivi cooked mixes with step 1 gained quail meat to be put into 80 DEG C, baking oven and dry 60 minutes, and gained drying composite super micron mill is pulverized, and mistake 500 mesh sieves obtain powder;
(3) Radix Sophorae Flavescentis, Radix sophorae, Radix Polygoni Runcinati, Radix Pottsiae Laxiflorae, Rhizoma Coptidis, Radix Scutellariae, Cortex sophorae, achillea millefolium, Folium Mali Asiaticae, Pericarpium Granati, magnificent carpinus turczaninowii, Pseudobulbus Bletillae (Rhizoma Bletillae), Rhizoma Trillii Tschonoskii, Radix Glycyrrhizae Preparata, Periostracum Cicadae are pulverized, and cross 50 mesh sieves and obtain coarse powder, for subsequent use;
(4) step (3) gained coarse powder adds step 1 gained filtrate, and soak 1 hour, slow fire boiling 1 hour, decocting liquid crosses 1000 order drainage screens, and gained filtrate is dried in the air cool to room temperature, for subsequent use;
(5) Bulbus Allii Cepae, Herba Portulacae are smash juice after cleaning, then cross 1000 order mesh screens, collect filtered juice;
(6) step (4) gained filtrate mixed homogeneously with step (5) gained filtered juice, cross 1000 filter screen filtration, gained filter vacuum is concentrated into the thick paste that relative density is 1.30 ± 0.02 (60 DEG C);
(7) add in thick paste obtained in step (6) by powder obtained in step (2), stirring and evenly mixing, granulate, granulate, tabletting is made sheet and is weighed the tablet of 0.2 gram and get final product.
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CN105343267A (en) * | 2015-11-30 | 2016-02-24 | 青岛海之源智能技术有限公司 | Traditional Chinese medicine oral liquid for treating scalp pruritus and preparation method thereof |
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CN1156617A (en) * | 1996-12-23 | 1997-08-13 | 胡文元 | Skin health anti-inflammatory inuncta and producing process thereof |
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CN105343267A (en) * | 2015-11-30 | 2016-02-24 | 青岛海之源智能技术有限公司 | Traditional Chinese medicine oral liquid for treating scalp pruritus and preparation method thereof |
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