CN105250792A - Medicine used for treating pustular psoriasis - Google Patents
Medicine used for treating pustular psoriasis Download PDFInfo
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- CN105250792A CN105250792A CN201510815166.3A CN201510815166A CN105250792A CN 105250792 A CN105250792 A CN 105250792A CN 201510815166 A CN201510815166 A CN 201510815166A CN 105250792 A CN105250792 A CN 105250792A
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Abstract
The invention discloses a medicine used for treating pustular psoriasis. The medicine is mainly prepared from the following raw materials in parts by weight: 9-15 parts of coptis root, 9-15 parts of amur corktree bark, 9-15 parts of Mongolian dandelion herb, 9-15 parts of bunge corydalis herb, 9-15 parts of giant knotweed rhizome, 9-15 parts of honeysuckle flower, 9-15 parts of weeping forsythia capsule, 9-15 parts of Indian buead, 9-15 parts of wild chrysanthemum, 9-15 parts of pagodatree flower bud, 9-15 parts of lalang grass rhizome, 9-15 parts of rehmannia root, 9-15 parts of suberect spatholobus stem, 3-5 parts of root of Sinkiang arnebia, 5-8 parts of red paeony root and 3-5 parts of Danshen root. The medicine has the characteristic of scientific compatibility of 16 natural traditional Chinese medicines, is simple in formula, has the effects of clearing away heat and toxic materials and diminishing swelling and removing pus through synergy of the active pharmaceutical ingredients, takes effect quickly, treats both symptoms and root causes, does not have toxic or side effect, is simple in preparation method, is convenient to take, is low in cost and has an effective rate over 94%.
Description
Technical field
The present invention relates to Chinese medicine, specifically one is used for the treatment of the psoriasic medicine of pustule-type.
Background technology
Psoriasis, formal name used at school is psoriasis vulgaris, is a kind of disease of chronic and refractory skin pruritus, is equivalent to neurodermatitis.For a kind of common chronic inflammatory dermatoses being easy to recur with characteristic skin lesion.From the beginning of being inflammatory red papules, about foxtail millet grain is to Semen phaseoli radiati size, and expanding gradually later or merging becomes brownish red speckle, clear border, and have inflammatory blush around, substrate infiltrates obviously, the canescence of surface coverage multilamellar drying or silvery white squama.Scraper surface squama gently, exposes the semitransparent thin film that one deck pale red is shinny gradually, claims film phenomenon.Strike off thin film again, then occur little petechia, claim petechial hemorrhage phenomenon.White squama, shinny thin film and petechial hemorrhage are the psoriasic key characters of diagnosis, are called that three levy.Psoriasis skin lesion is broadly divided into three periods from occurring to finally to disappear: carry out phase, resting stage, catagen.Clinical characters is skin lichenization, plump coarse, acute pruritus, and the course of disease is slow, recurrent exerbation, and constant year does not heal, easily recurrence more.Multiplely be born in the positions such as neck, elbow, sacrum, turn to feature with skin pruritus, lichen.
According to skin lesion range size, topical type and general hair style two type can be divided into clinically.According to Chinese medical discrimination, be broadly divided into three types: blood-heat cow tinea, pustule-type psoriasis and blood stasis type psoriasis.Wherein pustule-type psoriatic was often sent out in the phase of carrying out, have in noxious dampness accumulate and pent-up in blood system.The course of disease is slightly long, and erythra is scarlet, and there are densely covered syringe needle or the large pustule of Semen setariae in skin lesion place, has squama, a dry incrustation after pustule 1-2 week.
Psoriasis is a kind of local skin delayed ischemic neurological deficits illness, and comparatively common in life, inducement is many, and heavy time light during symptom, protracted course of disease can produce many harmful effects the orthobiosis to patient and household.Primary disease is chronic process, heavy time light during symptom, easily recurrence after curing.Severe patient can secondary folliculitis and lymphadenitis.Scratch friction shank or upper back of persistency can cause starch material to be deposited on corium, and then develops into plaque-like and lichen property amyloid disease respectively.
Present is main mainly with western medicine, but effect is comparatively slow, and its side effect is large, can cause other diseases.And the therapeutic efficiency of some current Chinese medicines is also not satisfactory, and curative effect is not remarkable.
Summary of the invention
The object of this invention is to provide a kind of good effect, short treating period, cost low, have no side effect be used for the treatment of the psoriasic medicine of pustule-type.
The technical scheme realizing the object of the invention is:
One is used for the treatment of the psoriasic medicine of pustule-type, and the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 9-15 part, Cortex Phellodendri 9-15 part, Herba Taraxaci 9-15 part, Herba Violae 9-15 part, Rhizoma Polygoni Cuspidati 9-15 part, Flos Lonicerae 9-15 part, Fructus Forsythiae 9-15 part, Poria 9-15 part, Flos Chrysanthemi Indici 9-15 part, Flos Sophorae 9-15 part, Rhizoma Imperatae 9-15 part, Radix Rehmanniae 9-15 part, Caulis Spatholobi 9-15 part, Radix Arnebiae (Radix Lithospermi) 3-5 part, Radix Paeoniae Rubra 5-8 part, Radix Salviae Miltiorrhizae 3-5 part.
Above-mentionedly be used for the treatment of the psoriasic medicine of pustule-type, optimum weight part proportioning of each raw material is:
Rhizoma Coptidis 12 parts, Cortex Phellodendri 12 parts, Herba Taraxaci 12 parts, Herba Violae 12 parts, Rhizoma Polygoni Cuspidati 12 parts, Flos Lonicerae 12 parts, Fructus Forsythiae 12 parts, 12 parts, Poria, Flos Chrysanthemi Indici 12 parts, 12 parts, Flos Sophorae, Rhizoma Imperatae 12 parts, 12 parts, the Radix Rehmanniae, Caulis Spatholobi 12 parts, Radix Arnebiae (Radix Lithospermi) 4 parts, Radix Paeoniae Rubra 6 parts, Radix Salviae Miltiorrhizae 4 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 30-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
In the present invention, pharmacology, effect of each crude drug are as follows:
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.Damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, palpitation and uneasiness, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, and carbuncle treats skin ulcer; External treatment eczema, eczema, auditory meatus is suppurated.
Cortex Phellodendri: have heat clearing and damp drying, pathogenic fire purging removes steams, effect of detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, beriberi flaccidity is knitted, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema eczema.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Herba Taraxaci: have the effects such as diuresis, cathartic, jaundice eliminating subcutaneous ulcer, function of gallbladder promoting.Control pyretic toxicity, carbuncle, skin infection, abscess of internal organ, conjunctival congestion and swelling pain, damp and hot, the puckery pain of jaundice, dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Herba Violae: heat-clearing and toxic substances removing.Control the high heat of epidemic febrile disease irritated, influenza, infectious hepatitis, nephritis, scrofula, parotitis, furuncle and other pyogenic infection.
Rhizoma Polygoni Cuspidati: there is dampness removing jaundice eliminating, heat-clearing and toxic substances removing, eliminating stasis to stop pain, effect of relieving cough and resolving phlegm.For jaundice due to damp-heat, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, burn due to hot liquid or fire, amenorrhea, lump in the abdomen, instep plays damage, cough due to lung-heat.
Flos Lonicerae: can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, send out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain.
Fructus Forsythiae: heat clearing away, removing toxic substances, eliminating stagnation, detumescence.Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction.
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating, mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Flos Chrysanthemi Indici: tool dispelling wind and heat pathogens, subduing swelling and detoxicating.Furuncle carbuncle, laryngopharynx swelling and pain, wind-fire acute conjunctivitis can be treated, the disease such as dizzy of having a headache.
Flos Sophorae: cooling blood for hemostasis, purging liver-fire.For having blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, spit blood, epistaxis, liver-heat conjunctival congestion, has a headache dizzy.
Rhizoma Imperatae: cooling blood for hemostasis, clearing away heat and promoting diuresis.Spit blood for heat in blood, epistaxis, hematuria, calentura excessive thirst, cough due to lung-heat, gastropyretic vomiting, jaundice due to damp-heat, edema oliguria, the puckery pain of pyretic stranguria.
The Radix Rehmanniae: there is clearing away heat and cooling blood, effect that tonifying YIN promotes the production of body fluid.To join the army blood for warm febrile disease, high fever coma, xerostomia crimson tongue.
Caulis Spatholobi: there is blood circulation promoting and enriching, menstruction regulating and pain relieving, effect of relaxing muscles and tendons and activating QI and blood in the collateral.For menoxenia, dysmenorrhea, amenorrhea, rheumatic arthralgia, paralysis and numbness, blood deficiency and yellow complexion.
Radix Arnebiae (Radix Lithospermi): removing heat from blood, invigorates blood circulation, removing toxic substances rash.Contain for heat in blood poison, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Warm macule, jaundice due to damp-heat, purpura, tells, is defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer.
Radix Paeoniae Rubra: clearing away heat and cooling blood, eliminating stasis to stop pain.For thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
Radix Salviae Miltiorrhizae: have blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
The present invention is used for the treatment of the psoriasic medicine of pustule-type, and choose 16 kinds of natural Chinese medicine scientific compatibility, formula is simple, the effect that each crude drug synergism plays heat-clearing and toxic substances removing, pus is removed in detumescence, instant effect, treating both the principal and secondary aspects of a disease, have no side effect, and its preparation method is simple, taking convenience, cost is low.
Detailed description of the invention
Below in conjunction with embodiment, content of the present invention is further described, but is not limitation of the invention.
Embodiment 1
One is used for the treatment of the psoriasic medicine of pustule-type, and the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 9kg, Cortex Phellodendri 9kg, Herba Taraxaci 9kg, Herba Violae 9kg, Rhizoma Polygoni Cuspidati 9kg, Flos Lonicerae 9kg, Fructus Forsythiae 9kg, Poria 9kg, Flos Chrysanthemi Indici 9kg, Flos Sophorae 9kg, Rhizoma Imperatae 9kg, Radix Rehmanniae 9kg, Caulis Spatholobi 9kg, Radix Arnebiae (Radix Lithospermi) 3kg, Radix Paeoniae Rubra 5kg, Radix Salviae Miltiorrhizae 3kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 10 times, decoct 30min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 50 DEG C, add adjuvant, make tablet, every sheet 0.1g.
Embodiment 2
One is used for the treatment of the psoriasic medicine of pustule-type, and the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 12kg, Cortex Phellodendri 12kg, Herba Taraxaci 12kg, Herba Violae 12kg, Rhizoma Polygoni Cuspidati 12kg, Flos Lonicerae 12kg, Fructus Forsythiae 12kg, Poria 12kg, Flos Chrysanthemi Indici 12kg, Flos Sophorae 12kg, Rhizoma Imperatae 12kg, Radix Rehmanniae 12kg, Caulis Spatholobi 12kg, Radix Arnebiae (Radix Lithospermi) 4kg, Radix Paeoniae Rubra 6kg, Radix Salviae Miltiorrhizae 4kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 15 times, decoct 34min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.20 that filtrate is concentrated into relative density at 53 DEG C, add adjuvant, make tablet, every sheet 0.2g.
Embodiment 3
One is used for the treatment of the psoriasic medicine of pustule-type, and the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 15kg, Cortex Phellodendri 15kg, Herba Taraxaci 15kg, Herba Violae 15kg, Rhizoma Polygoni Cuspidati 15kg, Flos Lonicerae 15kg, Fructus Forsythiae 15kg, Poria 15kg, Flos Chrysanthemi Indici 15kg, Flos Sophorae 15kg, Rhizoma Imperatae 15kg, Radix Rehmanniae 15kg, Caulis Spatholobi 15kg, Radix Arnebiae (Radix Lithospermi) 15kg, Radix Paeoniae Rubra 15kg, Radix Salviae Miltiorrhizae 15kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 18 times, decoct 37min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 57 DEG C, add adjuvant, make pill, every 0.4g.
Embodiment 4
One is used for the treatment of the psoriasic medicine of pustule-type, and the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 15kg, Cortex Phellodendri 15kg, Herba Taraxaci 15kg, Herba Violae 15kg, Rhizoma Polygoni Cuspidati 15kg, Flos Lonicerae 15kg, Fructus Forsythiae 15kg, Poria 15kg, Flos Chrysanthemi Indici 15kg, Flos Sophorae 15kg, Rhizoma Imperatae 15kg, Radix Rehmanniae 15kg, Caulis Spatholobi 15kg, Radix Arnebiae (Radix Lithospermi) 15kg, Radix Paeoniae Rubra 15kg, Radix Salviae Miltiorrhizae 15kg.
Preparation method is as follows: take the mixing of each crude drug be placed in container by above-mentioned, then add the soak by water 3 times of material quantity weight 20 times, decoct 40min at every turn, merge decoction liquor, filter and remove residue, it is the extractum of 1.30 that filtrate is concentrated into relative density at 60 DEG C, add adjuvant, make pill, every 0.5g.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, selecting 100 examples of accepting for medical treatment in patient, clinical observation is carried out to the curative effect of medicine of the present invention.Age 30-60 year, be divided into 4 groups at random, often group be 25 example, be respectively experimental group 1-4 group.
Experimental group 1-4 group takes the medicine of embodiment 1-4 respectively, every day 3 times, each 3 slices/for oral administration, within 7 days, is a course for the treatment of, takes 2 courses for the treatment of continuously.Wherein effective 92 examples, effective 94 examples, cure 90 examples, invalid 6 examples, cure rate 90%, effective percentage 94%.
Claims (3)
1. be used for the treatment of the psoriasic medicine of pustule-type, it is characterized in that: the raw material primarily of following weight parts proportioning is made:
Rhizoma Coptidis 9-15 part, Cortex Phellodendri 9-15 part, Herba Taraxaci 9-15 part, Herba Violae 9-15 part, Rhizoma Polygoni Cuspidati 9-15 part, Flos Lonicerae 9-15 part, Fructus Forsythiae 9-15 part, Poria 9-15 part, Flos Chrysanthemi Indici 9-15 part, Flos Sophorae 9-15 part, Rhizoma Imperatae 9-15 part, Radix Rehmanniae 9-15 part, Caulis Spatholobi 9-15 part, Radix Arnebiae (Radix Lithospermi) 3-5 part, Radix Paeoniae Rubra 5-8 part, Radix Salviae Miltiorrhizae 3-5 part.
2. be according to claim 1ly used for the treatment of the psoriasic medicine of pustule-type, it is characterized in that: optimum weight part proportioning of each raw material is:
Rhizoma Coptidis 12 parts, Cortex Phellodendri 12 parts, Herba Taraxaci 12 parts, Herba Violae 12 parts, Rhizoma Polygoni Cuspidati 12 parts, Flos Lonicerae 12 parts, Fructus Forsythiae 12 parts, 12 parts, Poria, Flos Chrysanthemi Indici 12 parts, 12 parts, Flos Sophorae, Rhizoma Imperatae 12 parts, 12 parts, the Radix Rehmanniae, Caulis Spatholobi 12 parts, Radix Arnebiae (Radix Lithospermi) 4 parts, Radix Paeoniae Rubra 6 parts, Radix Salviae Miltiorrhizae 4 parts.
3. be according to claim 1ly used for the treatment of the psoriasic medicine of pustule-type, it is characterized in that:
Preparation method is as follows: take each crude drug by weight ratio, add mixing and be placed in container, add material quantity weight 10-20 soak by water doubly 3 times again, each decoction 30-40min, merges decoction liquor, filter and remove residue, it is the extractum of 1.20-1.30 that filtrate is concentrated into relative density at 50-60 DEG C, add adjuvant, make corresponding dosage form, to obtain final product.
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| CN201510815166.3A CN105250792A (en) | 2015-11-23 | 2015-11-23 | Medicine used for treating pustular psoriasis |
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| CN201510815166.3A CN105250792A (en) | 2015-11-23 | 2015-11-23 | Medicine used for treating pustular psoriasis |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075164A (en) * | 2016-08-16 | 2016-11-09 | 黄琴 | For antipsoriatics thing |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091267A (en) * | 2011-01-14 | 2011-06-15 | 王涛 | Medicament for treating psoriasis vulgaris and preparation method thereof |
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2015
- 2015-11-23 CN CN201510815166.3A patent/CN105250792A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102091267A (en) * | 2011-01-14 | 2011-06-15 | 王涛 | Medicament for treating psoriasis vulgaris and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 中华中医药学会皮肤科分会等: "寻常型银屑病( 白疕) 中医药循证临床实践指南( 2013 版)", 《中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075164A (en) * | 2016-08-16 | 2016-11-09 | 黄琴 | For antipsoriatics thing |
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