CN105380051A - Beverage capable of dispelling alcohol effect and protecting liver and preparation method of beverage - Google Patents

Beverage capable of dispelling alcohol effect and protecting liver and preparation method of beverage Download PDF

Info

Publication number
CN105380051A
CN105380051A CN201510764882.3A CN201510764882A CN105380051A CN 105380051 A CN105380051 A CN 105380051A CN 201510764882 A CN201510764882 A CN 201510764882A CN 105380051 A CN105380051 A CN 105380051A
Authority
CN
China
Prior art keywords
prescription
liver
acid
alcohol
beverage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201510764882.3A
Other languages
Chinese (zh)
Other versions
CN105380051B (en
Inventor
严建军
张少华
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qinghai Ganluyin Biotechnology Co Ltd
Original Assignee
Qinghai Ganluyin Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qinghai Ganluyin Biotechnology Co Ltd filed Critical Qinghai Ganluyin Biotechnology Co Ltd
Priority to CN201510764882.3A priority Critical patent/CN105380051B/en
Publication of CN105380051A publication Critical patent/CN105380051A/en
Application granted granted Critical
Publication of CN105380051B publication Critical patent/CN105380051B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/38—Other non-alcoholic beverages
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention provides a beverage capable of dispelling the alcohol effect and protecting liver. According to the invention, (1) the beverage comprises a component A and a component (B); (2) the component A is prepared from extracts of the following raw materials: roots of kirilow rhodiola, hawthorn fruits, kudzu vine roots, smoked plums and liquorice roots; and (3) the component B is prepared from extracts of the following raw materials: Indian buead, wolfberry fruits, manyflower solomonseal rhizomes, wrinkled giant hyssop, honeysuckles and cinnamons. The beverage capable of dispelling the alcohol effect and protecting the liver also comprises honey, white granulated sugar and water. The invention further relates to the beverage and a preparation method thereof and particularly relates to the beverage capable of dispelling the alcohol effect and protecting the liver and the preparation method thereof.

Description

A kind of anti-alcohol and liver-protection beverage and preparation method thereof
Technical field
The present invention relates to a kind of beverage and preparation method thereof, particularly relate to a kind of anti-alcohol and liver-protection beverage and preparation method thereof.
Background technology
China is the native place of wine, is also the cradle of spirits culture, is one of country of making wine in the world the earliest.China's liquor-making history is long, various in style, from the day of generation, is just subject to ancients and welcomes.In China's development of civilization history of thousands of years, the development of wine and culture is synchronously carried out substantially.When red-letter day, sacrifice, party, a lot of scholar lay Buddhist is to drink as elegant taste.Much famous poetry is also relevant with wine, " life is proud must enjoy oneself to the full; do not make golden cup sky to the moon " of such as li po, " what time bright moon has, and takes up one's wine cup and ask of the Heaven " of Soviet Union's horizontal bar in the front of a carriage used as an armrest, " cuping to cup calls for song; how long is man's life " of Cao behaviour, " daytime sings and must indulge in drinking, and the youth keeps company and returns to one's native " of Tu Fu, Wang Wei " advise the more most a Glass Of Wine of monarch, the Yanguan Pass that exports to the west is without old friend " etc.
China's traditional medicine is thought, wine is hot in nature, and taste is pungent, sweet, is attributed to the heart channel of Hang-Shaoyin, Liver Channel.It is promoting blood circulation and removing blood stasis that wine is essential substances from water and cereals has, dredging the channel, expelling wind and clearing away cold, the effect of the long-pending cold stomach invigorating that disappears.Essentials of Matea Medica is recorded: " few drink then with blood fortune, strong god's resisting cold, gives vent to one's feelings and relieves the lonliness and grief, and diction is evil in dirty, warm internal organ, row medicine gesture.Excessive consumption of alcohol is then overtaxed one's nerves hematozemia, damages the bright essence of stomach, raw phlegm of getting angry, and angryly helps wish, to sick damp and hot all.”
Excessive consumption of alcohol can suppress the respiratory center of brain, cause breathe stop, also suppressing the decomposition of hepatic glycogen, make liver glycogen can not be converted into glucose in time, cause blood sugar decline also entail dangers to life.There is a lot of antialcoholic drug on the market, the symptoms such as the dizziness caused in order to alleviation of alcohol excessive concentration, vomiting at present.These drug side-effects are comparatively large, can bring extra burden to liver and renal metabolism.Also have the health drink of some relieving alcoholism and protecting livers on the market, but it is very slow to take effect, relieve the effect of alcohol, liver protecting DeGrain, market there is no desirable anti-alcohol and liver-protection beverage.
Summary of the invention
In order to solve the problem, the present invention is based on the ancient prescription described in Song dynasty's " formulary of peaceful benevolent dispensary ", select a kind of anti-alcohol and liver-protection beverage obtained by medicinal material of tens taste integration of drinking and medicinal herbs, it has the effect of relieving alcoholism and protecting liver and balance human body acid-base degree, simultaneously can improving eyesight calm the nerves, fall stomach fire, hypotensive, foster the spirit of nobility, delay senility, improve immunity etc. except halitosis, lipopenicillinase beauty treatment, clearing heat and promoting fluid, invigorating the spleen.
A kind of anti-alcohol and liver-protection beverage:
(1) prescription A and prescription B is comprised;
(2) extract consisting of following material of described prescription A: rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae;
(3) extract consisting of following material of described prescription B: Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree;
Described anti-alcohol and liver-protection beverage also comprises honey, white granulated sugar and water.
In described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 32-44 part, hawthorn 24-36 part, root of kudzu vine 20-32 part, dark plum 6-16 part, Radix Glycyrrhizae 4-14 part;
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 28-42 part, matrimony vine 12-24 part, sealwort 8-20 part, wrinkled giant hyssop 2-12 part, honeysuckle 1-10 part, Chinese cassia tree 1-8 part.
As a kind of preferred technical scheme of the present invention, in described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 36-42 part, hawthorn 26-34 part, root of kudzu vine 22-30 part, dark plum 8-14 part, Radix Glycyrrhizae 6-12 part;
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 30-40 part, matrimony vine 14-22 part, sealwort 10-18 part, wrinkled giant hyssop 4-10 part, honeysuckle 2-8 part, Chinese cassia tree 1-6 part.
As a kind of preferred technical scheme of the present invention, in described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 38-40 part, hawthorn 28-32 part, root of kudzu vine 24-28 part, dark plum 10-12 part, Radix Glycyrrhizae 8-10 part;
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 32-38 part, matrimony vine 16-20 part, sealwort 12-16 part, wrinkled giant hyssop 6-8 part, honeysuckle 4-6 part, Chinese cassia tree 2-4 part.
With parts by weight, contain in every 10000 parts of finished beverage:
Prescription A86-142 part
Prescription B52-116 part
Honey 300-500 part
White granulated sugar 150-300 part
Water surplus.
The compound method of described prescription A is:
(1) rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae washes clean will be weighed;
(2) filter extraction by after drug decocting 3-5 time after cleaning, the water yield at every turn added be the 6-8 of former dose doubly, extract and obtain separation and purification after extract.
As a kind of preferred technical scheme of the present invention, in the step (2) of the compound method of described prescription A, extraction temperature is 60-80 .
The compound method of described prescription B is:
(1) pulverize after load weighted Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree washes clean;
(2) supercritical carbon dioxide extracting is used.
As a kind of preferred technical scheme of the present invention, in the step (2) of the compound method of described prescription B, extraction temperature is 30-35 , extracting pressure is 18-25MPa, and resolution temperature is 42-53 , parsing pressure is 5-7MPa.
The present invention also provides a kind of method preparing anti-alcohol and liver-protection beverage, and described preparation method is:
(1) by heating for dissolving after the mixing of prescription A, prescription B and water;
(2) be cooled to room temperature, add honey, white granulated sugar, filtration, sterilizing, filling, to obtain final product.
Anti-alcohol and liver-protection beverage provided by the invention does not add anticorrisive agent, does not add pigment, without food additives.
Detailed description of the invention
Unless otherwise defined, all technology used herein and scientific terminology have the identical implication usually understood with one skilled in the art of the present invention.When there is contradiction, be as the criterion with the definition in this description.
During the Range Representation that equivalent, concentration or other value or parameter limit with scope, preferable range or a series of upper limit preferred value and lower preferable values, this is appreciated that all scopes specifically disclosing and formed by arbitrary pairing of any range limit or preferred value and any range lower limit or preferred value, no matter and whether this scope separately discloses.Such as, when disclosing scope " 1 to 5 ", described scope should be interpreted as comprising scope " 1 to 4 ", " 1 to 3 ", " 1-2 ", " 1-2 and 4-5 ", " 1-3 and 5 " etc.When number range is described in this article, unless otherwise indicated, otherwise this scope intention comprises its end value and all integers within the scope of this and mark.
Alcohol, formal name used at school ethanol.Ethanol after entering human body the organ such as very fast direct oral cavity, esophagus, stomach, intestines directly enter blood circulation by biomembrane, be promptly transported to each histoorgan of whole body and carry out metabolism.The ethanol of more than 90% absorbs at stomach and intestines place, and the ethanol absorbed enters liver through blood circulation.Ethanol less than 10% not by oxidation Decomposition, but is directly discharged by kidney or breathes out from respiratory tract through lung or go out through sweat gland of skin secretion from urine.
The catabolism of ethanol in human body is mainly by two kinds of enzymes in the enzyme system of liver: one is alcohol dehydrogenase (ADH), and another kind is acetaldehyde dehydrogenase (ALDH).Ethanol is mainly through for carrying out metabolism in intracytoplasmic ADH metabolic system, and under the effect of ADH, ethanol is catalyzed is oxidized to acetaldehyde.In mitochondria, acetaldehyde is converted into acetic acid under the catalytic action of ALDH, and acetic acid enters tricarboxylic acid cycle with the form of acetyl coenzyme A (writing acetyl-CoA), is oxidized to water and carbon dioxide, produces a large amount of ATP (atriphos) simultaneously.ADH and ALDH in liver is at DPN (NADH, NAD +) participation under metabolism generation effect to ethanol.H +transfer to NAD (NAD) from substrate, make it change NADH (DPNH) into, therefore NADH is oxidized obtains NAD +speed determine the metabolic rate of ethanol.
Ethanol can also carry out metabolism by the MEOS (MEOS) in endoplasmic reticulum, ethanol is by DPNH I (nicotinamide-adenine dinucleotide phosphate, NADPH) oxidizedly obtain acetaldehyde, DPNH I is converted into NAD I (NADP +).This metabolic process needs the participation of Cytochrome P450 just can complete.
In addition, ethanol can also in peroxisome, by catalase (CAT) approach generation metabolism.
In ADH metabolic system, the acetaldehyde of the oxidized generation of ethanol is the direct effect causing hepatic injury, and it can make liver cell mitochondrial impaired, thus makes liver cell to fatty acid decomposition function reduction, forms fatty liver.After acetaldehyde enters blood, under xanthine oxidase effect, generate superoxides, can lipid peroxidation be caused, cause hepatic injury initiation liver cell weak.Acetaldehyde can also and protein bound, cause protein function disorderly, stimulate fiber to generate and induce immune response, cause liver cell impaired once again.
In MEOS metabolic process, Cytochrome P450 in the highest flight, and it relates to the metabolism of multiple in-vitro compound (comprising carcinogenic substance), and the metabolism of ethanol can induce endoplasmic reticulum hyperblastosis, thus causes hepatic injury.
Mitochondria is main storage and the Workplace of oxygen in cell, the metabolism of ethanol in liver can cause reduced glutathione in mitochondria (GSH) activity to select to decline, the oxygen free radical causing respiratory chain to produce can not be delivered in time, and under the effect of active sod (SOD), form hydrogen peroxide, and then destroy the activity of SOD, cause mitochondrial lipid peroxidation, cause liver cell DNA cleavage, thus cause liver cancer to become.
The invention provides a kind of anti-alcohol and liver-protection beverage,
(1) prescription A and prescription B is comprised;
(2) extract consisting of following material of described prescription A: rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae;
(3) extract consisting of following material of described prescription B: Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree;
Described anti-alcohol and liver-protection beverage also comprises honey, white granulated sugar and water.
prescription A
Prescription A is the prescription that relieves the effect of alcohol, and described prescription A is made up of the extract of following material: rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae.
rhodiola root.cold in nature, taste is sweet, bitter, returns lung, the heart channel of Hang-Shaoyin.Have and have tonifying Qi clearing lung-heat, intelligence development is nourished heart, effect of controlling of bleeding with astringents, eliminating stasis to subdue swelling.The Four-Volume Medical Code is recorded: " flat, the puckery of property, kind moistening lung, can kidney tonifying, regulate the flow of vital energy and nourish blood.Cure mainly the diseases such as the whole body is weak, uncomfortable in chest, nauseating, body is empty." " Jingzhubencao " record: " and rhodiola root is invigorated blood circulation, and clearing lung-heat, cough-relieving are brought down a fever, pain relieving, be used for the treatment of pneumonia, tracheitis, in poor health, malaise, uncomfortable in chest, be difficult to breathe freely, lip and the palm of the hand blue." Compendium of Material Medica record: " rhodiola root, herbal classic is top grade, eliminating evil bad odor, mends various symptims and signs of deficiency." supplement to Thousand Golden Prescriptions record: " acid of red-spotted stonecrop bitter is flat, nontoxic.Main large hot mycotic ulcer caused by venereal disease, body heat is tired, evil gas, all disease due to noxious agents produced by various parasites scab arranges, fever and chills wandering arthritis, and various symptims and signs of deficiency, spends main woman's whitish metrorrhagia, clear body improving eyesight, and the logical god of clothes is not old for a long time." " Chinese medicine voluminous dictionary " record: " and cold in nature, sweet-puckery flavor.Promoting blood circulation and hemostasis, removing heat from the lung to relieve cough.Control hemoptysis, spitting of blood, pneumonia is coughed." " Chinese herbal medicine is commonly used in Tibet " record: " rhodiola root has promoting blood circulation and hemostasis, removing heat from the lung to relieve cough, antipyretic and effect only under band.Cure mainly the diseases such as hemoptysis, pneumonia cough, women leukorrhea.”
The chemical composition of rhodiola root is glycoside, flavonoids, volatile oil, Coumarins, terpene, steroid class and alkaloids.
Glycoside: flavonol glycosides and benzene alkylglycosides, wherein flavonol glycosides is the main active chemical of Rhodida plant, become glycosides position at 3,7,8 or 4, general connection a part or two molecular saccharides, the kind of sugar mainly comprises glucose, rhamnose, arabinose and wood sugar; Benzene alkylglycosides is ethyl glycoside (rhodioside), Phenylpropanoid Glycosides glycoside (Rosavin) and phenolic glycoside.Rhodiola root is also containing glycosides such as monoterpene glycosides, isoquercitin glycosides, rutin glycosides, piceins in addition.
Flavonoids: flavonols, Quercetin, rutin and Kaempferol.
Volatile oil: have cinnamyl alcohol and some alcohol, aldehyde, alkene and ester.
Coumarins: cumarin, umbelliferone, henbane compounds etc.
Other: sitosterol, tannin, anthraquinone, pectin, tannin, terpene lactone compound, alkaloids, cellulose family, fat, protein, organic acid, starch based and abundant vitamins, amino acid and some important inorganic elements.
Glycosides compound in rhodiola root can strengthen the deposit of liver glycogen, is conducive to the metabolism of ethanol in liver, provides energy anti-fatigue, alleviates burden of liver.Simultaneously flavone compound can Yiqi-Huoxue-Huayu, increases amount of hemoglobin, improves blood oxygen content, improve aerobic metabolism process during body anoxic.
hawthorn.warm in nature, taste is sweet, sour, returns spleen, stomach, Liver Channel.Have food digesting stomach fortifying, promoting the circulation of qi is fallen apart the stasis of blood, changes effect of turbid lipopenicillinase." the southern regions of the Yunnan Province book on Chinese herbal medicine " is recorded: " meat that disappears stagnates, lower gas; Control acid regurgitation, long-pending block." Compendium of Material Medica record: " change diet, disappear meat Ji ， Disorder lump in the abdomen, the full acid regurgitation of phlegm and retained fluid ruffian, and stagnant blood pain is swollen." " Records of Tradition Chinese and Western Medicine in Combination " record: " hawthorn, if help it with sweet medicine, Removing Blood Stasis and do not hinder new blood, open strongly fragrant gas and do not hinder healthy tendency, the outstanding peace of its property is also." Tang Materia Medica record: " juice takes main profit, and hair washing and with it sore are itched." " Bencao Tujing " record: " control dysentery and Low Back Pain.”
Hawthorn, mainly containing flavonoids, flavane and polymer class thereof, organic acid, also has triterpenes and steroid etc.
Flavonoids: Vitexin, different Vitex negundo var cannabifolia, orientin, homo-orientin, Kaempferol, herbaceous stem element, rutin, Hyperoside, naringenin-5,7-pair-glucoside, Eriodictyol-5,3 '-bis--glucoside, Eriodictyol-7,3 '-bis-glucoside, texifolin, pesudotsuga taxifolia 3-O-β-arabopyranose glycosides, pesudotsuga taxifolia 3-O-β-xylopyranose glucosides.
Flavanoid: catechin, epicatechin, leucocianidol, front colored indigo A 2, PCA B 2, B 4, B 5, dimerization leucocianidol, PCA C 1, PCA D 1deng, PCA E 1.
Triterpenes: triterpene compound comprises these 5 kinds, Ursane, cycloartane type, oleanane type, lanolin alkane type and lupinane type.Ursane has ursolic acid, Corosolic acid; Cycloartane type has Huan Atun; Oleanane type has β-botany bar gum, uvaol, oleanolic acid, crataegolic acid; Lanolin alkane type has butyrospermol, 24-methylene-24-dihydro lanosterol; Lupinane type has betula camphor.
Steroid: cupreol, β-daucosterol, stigmasterol.
Organic acid: comprise phenolic acid class and other organic acid, liposoluble ingredient has benzoic acid, gallic acid, protocatechuic acid, chlorogenic acid, β-coumaric acid, caffeic acid, forulic acid, anisic acid, vanillic acid, syringic acid, gentianic acid etc.; Other organic acid comprises malic acid, citric acid, chinic acid, pyruvic acid, tartaric acid, palmitic acid, stearic acid, oleic acid, linoleic acid, butanedioic acid, fumaric acid, 2-(4-hydroxy benzenes) malic acid, gibberellic acid, ascorbic acid etc.
Amino acids: the acid of glutamate, methionine sulfoxide, aspartic acid, asparagine, glutamic acid, methyl amimoacetic acid, citrulling, proline, amion acetic acid, alanine, valine.
Ursolic acid, Hyperoside significantly can reduce the content of cholesterol in serum, triacylglycerol, improve the activity of SOD, prevent the formation of blood vessel scleratheroma.Flavone compound can reduce aliphatic acid toxic effect on liver cells, glutamic-pyruvic transaminase, glutamic-oxalacetic transaminease index is reduced, reaches the effect of relieving the effect of alcohol.The effect that Flavane compound has significant hemangiectasis, reduces blood pressure.
the root of kudzu vine.cool in nature, taste is sweet, pungent, attaches to the lung and stomach meridians.There is relieving muscles to expel heat, promoting eruption, promote the production of body fluid to quench thirst, rise effect of positive antidiarrheal.Compendium of Material Medica is recorded: " book on Chinese herbal medicine ten doses of clouds, expell the excess with mild diaphoretic, the genus of Chinese ephedra, the root of kudzu vine.Lid Chinese ephedra is Taiyang channel medicine, double enter lung channel, lung governing skin and hair; The root of kudzu vine is Yangming Channel medicine, double enter the spleen channel, spleen governing muscles.Disperse so two taste medicines all lightly float, and institute enters also far different." " Bencao Jingshu " record: " root of kudzu vine, dismisses the main medicine of positive bright warm disease heat evil also, therefore master quenches one's thirst, high fever of the body, and heat is stopped up chest diaphragm and vomitted.Disperse and rise, the property of wind medicine also, therefore leads all numbness." " cold headache is held concurrently the strong pain along spinal column of item and bone pain person all over, and, it is bright that heresy does not still enter sun to the sufficient sun yet, therefore without thirsty card, should not take." " book on Chinese herbal medicine converges and says " record: " root of kudzu vine, fresh breeze is trembled with fear, and only shows heresy, expelling pathogenic factors from muscles and skin heat, only polydipsia.Rush down the medicine of stomach fire also.Taste the medicine that loose heresy is delivered in sight, its product are also many, pull out sun battalion divide cold as Chinese ephedra, the wind that cassia twig Xie Taiyangwei divides, windproof, purple perilla falls apart the chill of the sun at table, and Jehol Ligusticum Rhizome, notopterygium root fall apart the cold-dampness of the sun at table, all claim to disperse medicine also, and dispersing of the root of kudzu vine, also enter the sun, also dispersing wind and cold, different again, if non-numb, osmanthus, Soviet Union, anti-, pungent fragrant temperature is dry, disperse and damage middle gas mistake also; If non-Jehol Ligusticum Rhizome, notopterygium root, disperse and have consumption ying blood anxiety also." Shennong's Herbal record: " quench one's thirst, high fever of the body, vomiting, all numbness, plays cloudy gas, separates all poison." " Mingyi Bielu " record: " cold middle wind headache of curing the wound, expelling pathogenic factors from muscles and skin delivers perspiration, loosing the interspaces of skin and muscles, treats metal-inflicted wound, only coerces wind pain.”
The main chemical composition of the root of kudzu vine is flavone compound, volatile oil compound, saponins compound, amino acid, alkaloid, phytosterin compound etc., and wherein flavonoid content is maximum.
Flavonoids: based on isoflavones, other be tectorigenin, irisolidon, onocerin, Glycitein, Daidezin, Quercetin, genistein, robinin, iridin, contg. glucoside of pueravia flower, glycitin, Nicotifiorin, sissoo glycosides, biochanin first, 6 "-O-wood sugar iridin, 6 "-O-wood sugar daidzin.
Volatile oil: n-docosane, thujopsene, Trans-caryophyllene, oxalene, hexadecylic acid, aldehyde C-9, the joyous benzylacetone of six hydrogen alloys, 2,6-diisobutyl paracresol, acetic acid terpin fat, methyl palmitate, dibutyl phthalate, camphor.
Saponins: soyasaponin I, soybean saponin A b, soyasaponin β g, kaikasaponin I, kaikasaponin III, glycyrrhizin.
Other: cupreol-3-O-β-D-Glucose glycosides, cupreol, N-caproyl-N 1-glucose-tryptophan, paraffin, p-coumaric acid, stigmasterol glycosides, daucosterol, trace element, protein, polysaccharide.
Irisin in the root of kudzu vine can suppress the activity of GRD beta-glucuronidase, and can recover the activity of glutathione sulfydryl transferase and glutathione, plays the effect of relieving alcoholism and protecting liver.Irisin has protective effect to the Acute Hepatic steatosis caused because of ethanol, and mechanism, for improving mitochondrial function, reduces the activity of triglycerides, glutamic-pyruvic transaminase and glutamic-oxalacetic transaminease, regulates membrane potential level and mitochondrial permeability.Purpleking iris (Iris germanica var nepalensis) glycosides can play the effect of relieving alcoholism and protecting liver, and contg. glucoside of pueravia flower oral after under the effect of intestinal flora can metabolism become purpleking iris (Iris germanica var nepalensis) glycosides.
dark plum.property is put down, and taste acid, returns liver, spleen, lung, large intestine channel.Have and astringe the lung, puckery intestines, promote the production of body fluid, effect of claming ascaris." Bencao Jingshu " is recorded: " plum is real, and namely the dark plum of the present is also, the sourest." warp " is said: heat impairing qi, and evil visitor is in the heart, then gas superinverse and dysphoria, the heart is uneasy for it.The acid of dark plum taste, can hold back superficial heat, air-breathing can return unit, therefore main lower gas, heat extraction dysphoria and feeling at ease also.Diarrhea person, large intestine collapse is also; Good saliva dry person, flaring up of deficient fire, body fluid deficiency also; Acid can hold back the fire of deficiency type, change body fluid, solid intestines take off, so lead also.Its main limbs pain, hemiplegia meciless person, covers because moisture is dipped in channels and collaterals, then muscle arteries and veins relaxes vertical, or pain is meciless; Liver governing tendons, sour in taste acting on the liver and nourishing the muscle and tendon, liver obtain support, then solid skeleton and pliable tendons, machine-operated tonneau and front card removes.”
Wine is hot, and dark plum taste is sour, can hold back superficial heat, air-breathing can return unit, and main lower gas, heat extraction dysphoria, feels at ease, and controls gastric disorder causing nausea dysphagic, antidysentery with astringent, and disappear wine poison.And can catharsis taste muscles and bones damp and hot, the unit of convergence spleen lung dissipation.But should not eat more, eat the injury of the bone more, erosion taste, make us heating.
Dark plum is containing the acid of Chinese holly edge, malic acid, oxalic acid, butanedioic acid and fumaric acid, and total acid content is about 4%-5.5%, more with first two organic acid content.Also containing HMF 5 hydroxymethyl 2 furaldehyde, it is colorless oil.Contained volatile ingredient, mainly contains benzaldehyde, 4-terpinenol, phenmethylol and hexadecanoic acid.Also containing picric acid, superoxide dismutase, amygdalin.
Organic monoacid wherein, especially the acid of Chinese holly edge and malic acid can improve the sour environment of taste, and reducing human, to the absorption of ethanol, enables the direct metabolism in stomach without liver of part ethanol, alleviate burden of liver, play effect of relieving alcoholism and protecting liver from the side.
Dark plum also can protect stomach, sterilization, prevents food from degenerating in stomach, improves a poor appetite, and prevents aging, can also remove halitosis after drinking.In addition, dark plum has contraction to gall-bladder, can promote bile excretion.
radix Glycyrrhizae.property is put down, and taste is sweet, the thoughts of returning home, lung, spleen, stomach warp.Have and invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, effect of coordinating the drug actions of a prescription." medicineization justice " is recorded: " Radix Glycyrrhizae, raw with cool and purging intense heat, main loose table is evil, subduing inflammation, relieve sore throat pain, separates hundred medicines poison, except stomach accumulated heat, goes urinary catheter pain, and the power of this sweet cool heat extraction also.Process the bowl spares by temperature, main insufficiency of the spleen cunning is rushed down, and stomach void is thirsty, and fever and chills are coughed, and breathe hard sleepy, forced labour is deficient, and this sweet temperature helps the merit of spleen also.But rich and too sweet, unsuitable multiplex in tonic, probably love diaphragm does not think food yet." " book on Chinese herbal medicine is just " record: " and Radix Glycyrrhizae, taste to sweet, obtains the property of neutralization, has the merit adjusting benefits, therefore its poison of solution that poison obtains, and firm medicine obtains its property of sum, and what medicine administered to bring out the cold obtained helps outside it, put in poison slow it is fast.Help ginseng, merit that stilbene becomes the deficiency of vital energy, known to people also, help cultivated land to treat the danger of the deficiency of Yin, who its dawn here.Eliminating evil heat, hard muscles and bones, strengthening the spleen and stomach, longue meat.Enter gas with gas medicine, enter blood with blood medicine, without toward can not, therefore claim state old.Only, full person does not add, and probably it does swollen; Speed lower person do not enter, and probably its slow merit, can not know yet.”
Radix Glycyrrhizae root welding technology master is containing triterpenoid saponin.Wherein main one, being commonly called as glycyrrhizin, is the sweet ingredient of Radix Glycyrrhizae, is sylvite and calcium salt that the 18 β-enoxolone of 1 molecule and the glucuronic acid of 2 molecules combine the glycyrrhizic acid generated.Other triterpenoid saponin has: uralsaponin A, B and glycyrrhizic acid A 3, B 2, C 2, D 3, E 2, F 3, G 2, H 2, J 2, K 2.Again containing flavonol compounds: liquiritigenin, liquiritin, Isoliquiritigenin, isoliquiritin, neoliquriitin, close isoliquiritin, licoricidin, Licoricone, formoononetin, this fixed, liquiritigenin-4 of 5-O-methyl Radix Glycyrrhizae '-celery sugar glycoside, liquiritigenin-7, namely 4 '-diglucoside, vicenin-2 are 6,8-, bis--glucosyl group apiolin, ononin, isolicoflavonol, Isoliquiritigenin-4 '-celery sugar grape glucoside.Also containing Coumarins compound: Radix Glycyrrhizae coumarin, glycyol, isoglycyol, Radix Glycyrrhizae coumarin-7-methyl ether, neoglycyrol, Radix Glycyrrhizae pyrans coumarin, licocoumarone etc.Again containing alkaloid: 5,6,7,8-tetrahydrochysene-4-methylquinoline, 5,6,7,8-tetrahydrochysene-2,4-dimethyl quinolines, 3-methyl-6,7,8-tri-hydrogen pyrrolo-[1,2-a] pyrimidine-3-ketone.Also containing licobenzofuran, have another name called liconeolignan, cupreol, n-tricosane, n-hexacosane, heptacosane etc.
The leaf of Radix Glycyrrhizae is containing chromocor compound: puriri glucoside-II, narcissin, nicotiflorin, rutin, Isoquercitrin, astragalin, uralenol, Xin Wuer alcohol, neouralenol, uralenin, Quercetin-3,3 '-dimethyl ether, Uralenol-3-methylether, uralene, Quercetin etc.Also containing uralenneoside.
The aerial part of Radix Glycyrrhizae is separated and obtains Scopoletin, formoononetin, lupinus luteus Wei Te ketone, second shape thorn ketone element B and Radix Glycyrrhizae peaceful A, B, C, D, E, L, M, N, O, P, Q, R, S, T, U, V.
Glycyrrhizin have very strong detoxication, can strengthen the removing toxic substances technical ability of liver.The hydrolysate glucuronic acid of glycyrrhizin is also the active ingredient of removing toxic substances.Radix Glycyrrhizae can recover liver glycogen and the rna content of accumulation in liver cell.Reduce the activity of glutamic-pyruvic transaminase in serum, can hepatic injury be suppressed.Reduce the accumulation of triglycerides in liver.Enoxolone can the generation of strong inhibition lipid peroxide, suppresses Ca 2+flow into the infringement caused in cell.
The large heat of wine is poisonous, is damp and hot heresy, and according to the principle for the treatment of heat syndrome with drugs of cold nature, prescription A, based on cold and cool material, forms with the relation compatibility of monarch.Wherein, control drunk dysphoria with smothery sensation for monarch drug in a prescription with rhodiola root, root of kudzu vine activating spleen by relieving alcoholism is ministerial drug, helps with hawthorn, dark plum, regulating qi-flowing for strengthening spleen, stopping nausea and vomiting by lowering the adverse flow of QI, separately adds Radix Glycyrrhizae for making.
In described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 32-44 part, hawthorn 24-36 part, root of kudzu vine 20-32 part, dark plum 6-16 part, Radix Glycyrrhizae 4-14 part;
As a kind of preferred technical scheme of the present invention, in described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 36-42 part, hawthorn 26-34 part, root of kudzu vine 22-30 part, dark plum 8-14 part, Radix Glycyrrhizae 6-12 part;
As a kind of preferred technical scheme of the present invention, in described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 38-40 part, hawthorn 28-32 part, root of kudzu vine 24-28 part, dark plum 10-12 part, Radix Glycyrrhizae 8-10 part.
prescription B
Prescription B is for protecting liver prescription, and described prescription B is made up of the extract of following material: Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree.
poria cocos.property is put down, and taste is sweet, the thoughts of returning home, lung, the spleen channel.There is eliminating dampness and diuresis, strengthening the spleen and stomach, effect of antitoxic heart-soothing and sedative.Compendium of Material Medica is recorded: " Poria cocos smell is light and ooze, and its property is up, born fluid, loosing the interspaces of skin and muscles, grows water source and declines, diuresis, therefore Zhang Jiegu calls its genus sun, floats and rises, saying its property also; Dong Yuan calls it for the YIN aspect of YANG, fall and under, Yan Qigong is also." amplification on Canon of Materia Medica record: " Poria cocos, fushen, the merit of row water is many, heart-spleen boosting can not fault also." " book on Chinese herbal medicine is just " record: " can dry by sharp key, sharp key is happy intelligence development then, leads turbid promoting the production of body fluid; Dry, dry spleen of relieving oedema or abdominal distension through diuresis or purgation, bowl spares stomach invigorating; Eradicates shies epilepsy, thick intestines and internal organs of the body, controls phlegm originally, helps falling of medicine.Have with its taste micro-sweet, therefore say yang-tonifying.But mend few benefit.”
Excessive consumption of alcohol can cause palpitation and restlessness, insomnia forgetfulness, insufficiency of the spleen few food, and effect that Poria cocos has a significant tonifying spleen dampness elimination simultaneously main sternal rib, against gas, to tackle the sound of vomiting of vomitting caused after drinking, is had loose bowels.Poria cocos joins Chinese cassia tree to activate yang, and can stimulate circulation, namely so-called " row gasified water ", " the capable water of gas is capable ".
Sclerotium is containing Multiple components: triterpenes, pachymic acid, 16 Alpha-hydroxy eburicoic acids, 3 beta-hydroxies-7,9 (11), 24-wool steroid triolefin-21-acid, pachymic acid methyl esters, 16 Alpha-hydroxy eburicoic acid methyl esters, 7,9 (11)-DHPA methyl esters, 3 β, 16 alpha-dihydroxy-s-7,9 (11), 24 (31)-wool steroid triolefin-21-acid methyl esters, total triterpenes methyl esters, the acid of 3-hydrogenation pine Siberian cocklebur, eburicoic acid, dehydroeburicoic acid, Poria cocos eo-acid, β-aromadendrol acetic acid, 7,9 (11) DHPAs.Polysaccharide, pachyman, Poria cocos time poly-, callose H11.Other, ergosterol, sad, caprylate, hendecanoic acid, laurate, lauric acid ester, palmitic acid, dodecylene acid esters and inorganic elements.
Beta-hydroxy wool steroid trienic acid and other hydroxyl acid containing unsaturated bond can reduce free glycan molecule in liver cell environment.Free sugar being changed into and combine sugar, is energy reserve by unavailable for human body Conversion of Energy, the system that sustains life complete.Namely the effect showed is reduce blood sugar and blood pressure.
matrimony vine.property flat, taste is sweet, returns liver, kidney channel, has effect of nourishing liver and kidney, benefiting shrewd head, moistening lung." explaining abstruseness of the canon of materia medica " is recorded: " the prosperous then bone of water is strong, and quenches one's thirst, and blurred vision, Low Back Pain goinyalgia heals invariably for the fruit of Chinese wolfberry, tonifying kidney and benefiting sperm.Flat and not hot by matrimony vine by matrimony vine, there are the energy of moisturizing system fire, merit same with glutinous rehmannia." " herbal diagram " record: " the sweet gas of fruit of Chinese wolfberry taste is put down, and kidney channel medicine is also.Tonifying kidney and benefiting sperm, the prosperous damp bone of water is strong, and quenches one's thirst, and blurred vision, Low Back Pain goinyalgia heals invariably.Tao Hongjing cloud: a thousand li of leaving home, does not eat matrimony vine.Very say that it mends smart reinforcing yin essence also." " book on Chinese herbal medicine newly organized " record: " and fruit of Chinese wolfberry Yiyang, and benefit of holding concurrently is cloudy, root bark of Chinese wolf-berry benefit is cloudy, and can not Yiyang also, but all non-monarch drug in a prescription of two things, can be deputies or assistants to army generals in ancient times general, matrimony vine helps positive medicine with Xing Yang, and the root bark of Chinese wolf-berry helps cloudy medicine with Pingyin also." " medicineization justice " record: " and matrimony vine, the enriching yin of body profit enters kidney and enriches blood, taste sweet supporing yang enter kidney tonifying Qi, therefore can improving sight and hearing, add marrow, muscle reinforcing and bone strengthening, nourish blood arteries and veins, treats consumptive disease and damage timid, joint gout, pain in the back knee swells, and the few profit of stool and urine, the disease of all kidney-KIN being deficients, knows and should use it.”
The purging the liver of pathogenic fire of matrimony vine energy is suffered from a deficiency of the kidney heat, can cool blood and correction gas, controls heat symptoms caused by an exopathgen in five, above except head wind pain, in flat costalgia of chest, lower sharp intestine and small intestine.Matrimony vine and sealwort collocation, can enrich blood by production of sperm, benefiting qi for tranquillization.
The ripening fruits of matrimony vine, containing betaine, maize xanthin, physalin, also contains amino acid: leucine, valine, proline, alanine, tyrosine, glutamine, glycine, glutamic acid, aspartic acid, asparagine, histidine, tryptophan.Again containing volatile ingredient, mainly safranal, alpha, beta-lonone, 3-hydroxy-beta-irisone, left-handed 1,2-dehydrogenation-α-rhizome of nutgrass flatsedge alkene, potato spiral shell dienone.Carrotene, thiamine, riboflavin, nicotinic acid, vitamin.Seed oil-containing, wherein non-saponified portions contains multiple sterol: what belong to 4-demethyl sterols has cholesterine, 7-cholestenol, campesterol, 24-methylenecholesterol, isofucosterol, stigmasterol, cupreol, 24-cholestadienol, 24-ethyl-cholestadienol, cholestanol, 24-methylcholestane alcohol, 24-ethyl-22-cholestenol; What belong to 4-methyl sterol alcohols has 31-demethyl cycloartanol, 31-demethyl cycloartenol, cycloeucalenol, 31-demethyl-8-lanostenol, 4 α, 14 α, 24-trimethyl-8,24-cholestadienol, 24-methyl-31-demethyl-9 (11)-lanostenol, 4 Alpha-Methyls,-8-cholestenol, 4-methyl-7-cholestenol, 4-methyl-24 ethyl-7-cholestenol, 4,24-dimethyl-cholestenol
Betaine in matrimony vine to lipid-metabolism, can play the effect preventing fatty liver.LBP-X can improve the activity of T cell thus improve body immunity.LBP-X also has obvious antitumor action.
sealwort.property is put down, and taste is sweet, returns spleen, stomach, kidney channel.There is boosting qi and nourishing yin, invigorating the spleen, moistening lung, effect of kidney-nourishing." herbal classic is met former " is recorded: " five Tibetan are in harmonious proportion, and muscle sufficiency, marrow is hard by force, is all the merit of tonifying yin for sealwort, wide middle beneficial gas." " book on Chinese herbal medicine is just read " record: " sealwort, for growing greasy product, clothes of a specified duration make us not hungry, have wet person if insufficiency of the spleen, should not take it, and probably its greasy diaphragm is also.These flavour of a drug are sweet as maltosemalt sugar, and the flat matter profit of property is the certified products of tonic spleen the moon." " Traditional Chinese Medicine in Sichuan will " record: " kidney tonifying moistening lung, benefiting qi and nourishing yin.Control insufficiency of the spleen Huang, cough due to deficiency of the lung, muscles and bones acid numbness is unable, and postpartum, qi and blood was weak.”
Hot-tempered distinguished gathering causes impairment of both QI and YIN, sealwort boosting qi and nourishing yin, property profit and soft, and kind tonifying five zang organs is deficient, the fraud of the helpless fire of beneficial gas.
The root-like stock of sealwort, containing steroid saponin, has isolated 2 furan steroid enol form saponins and 2 spirostene alcohol type saponins.Belong to the former: 26-O-β-D-glucopyranosyl-22-O-methyl-(25)-S-furan steroid-5-alkene-3 β, 26-glycol 3-O-β-lycotetraose glucoside and Herba Polygoni sibirici glucoside A and 26-O-β-D-glucopyranosyl-22-O-methyl-25 (S)-furan steroid-5-alkene-3 β, 14 α, 26-triol 3-O-β-lycotetraose glucoside i.e. 14 Alpha-hydroxy Herba Polygoni sibirici glucoside A; Belong to the latter: (23S, 25R)-spiral shell steroid-5-alkene-3 β, 14 α, 23-triol 3-O-β-lycotetraose glucoside and Herba Polygoni sibirici glucoside B and new bus draw time diosgenin-A 3-O-β-lycotetraose glucoside.Another containing Siberian solomonseal rhizome polysaccharide A, B, C, the relative molecular mass of three is all greater than 200,000, forms according to mol ratio 6:26:1 condensation by glucose, mannose and galacturonic acid; Again containing polygonatum rhizome oligosaccharide A, B, C, relative molecular mass is respectively 1630,862 and 472, is to be formed by fructose and glucose 8:1,4:1 and 2:1 condensation in molar ratio.
Sealwort can resisting pathogenic microbes, and the blood sugar caused adrenaline is too high in obvious inhibitory action, improves the activity of liver SOD, reduces the content of myocardium lipofuscin.Strengthen human T cell, booster immunization function, and the ability that can improve body hypoxia-bearing.
wrinkled giant hyssop.warm in nature, taste is pungent, returns spleen, stomach, lung channel.Have and eliminate dampness with aromatics, and middle preventing or arresting vomiting, deliver effect of relieving summer-heat." book on Chinese herbal medicine justice " is recorded: " delicate fragrance tepor, wet turbid sputum in kind reason Central Region, is outer stomach of being amusing, vibrates clear positive quality goods ... cholera pain in the chest and abdomen person; wet turbid retardance, and the gas injuring the clear sun of spleen soil is then suddenly formal confused, and angina of vomiting and diarrhoea; fragrance can help the clear gas in Central Region, and victory is wet wards off dirty, therefore is the seasonal key medicine of summer-heat and damp." " medicineization justice " record: " its gas Fang Xiang, benefaction stomach Qi, in adjusting with this, control vomiting cholera, with this fast gas, except dirty jailbird is vexed.And fragrant energy and conjunction the five internal organs, if incoordination between the spleen and the stomach, help stomach with it and enter diet, having the merit of appetizing of being amusing." Compendium of Material Medica record: " be elevated all gas, it is key medicine that taste are told inverse." " Mingyi Bielu " record: " geomantic omen poison is swollen, removes bad odor, only cholera pain in the chest and abdomen.”
Wrinkled giant hyssop can be controlled taste and tell inverse, inducing diaphoresis to expel pathogens, and dissolve the drunk caused part of the body cavity above the diaphragm housing the heart and lungs and stop up heat, halitosis, helps stomach and enter diet, has the merit of appetizing of being amusing.Wine is damp and hot thing, the cold-dampness, summer-heat and damp, hot and suffocating, damp and hot and wrinkled giant hyssop falls apart.But wrinkled giant hyssop belongs to sun, is the thing of generation, its property is sharp and fragrant loose, should not take more.
Wrinkled giant hyssop is containing volatile oil 0.28%, and main component is estragole, accounts for more than 80%.And containing anisole, anisaldehyde, (R)-4-isopropenyl-1-methyl-1-cyclohexene, and p-methoxyl group cinnaldehydrum, , nopinene, octanone-3, octanol-3, cymol, octen-1-ol-3, linalool, l-carypohyllene, beta-elemene, β-Humuleno, ylangene, β-farnesene, γ-Cadinene, calamenene etc.
Wrinkled giant hyssop containing estragole, anethole, anisaldehyde, citrene, methoxy cinnamaldehyde, , nopinene, 3-octanone, 1-OCOL, linalool, 1-cloves alkene, beta-elemene, β-Humuleno, ylangene, β-farnesene, γ-Cadinene, calamus alkene, also containing cis-beta, gamma-olefine aldehydr.Flavone compound: robinin, lime tree element, linarin, agastachoside, different agastachoside, wrinkled giant hyssop essence.Root is containing maslinic acid, oleanolic acid, 3-O-acetyl group oleanolic aldehyde, robinin, lime tree element, agastachoside, Daucosterol, cupreol, Dehydroagastol.
Wrinkled giant hyssop has antagonism to calcium ion, has the antagonistic activity composition to calcium ion, to K in agastache extract +spasm has inhibit activities.Reduce the Ca in cell membrane 2+flow controls being overexcited of smooth muscle, can alleviate vomiting and diarrhoea that the drunk organ contraction of muscle caused causes.
honeysuckle.cold in nature, taste is sweet, attaches to the lung and stomach meridians.There is clearing heat and detoxicating, that anti-inflammatory, qi-restoratives treat wind effect.Compendium of Material Medica is recorded: " control all rheumatism gas and all pyogenic infections, ulcer mange, red bayberry dislikes sore, heat radiation removing toxic substances." " the southern regions of the Yunnan Province book on Chinese herbal medicine " record: " heat-clearing, separates all sores, ulcer carbuncle on the back, red stream scrofula." " explaining abstruseness of the canon of materia medica " record: " and honeysuckle, main turgor diarrhea, the loose poison of the carbuncle that disappears, qi-restoratives treats wind, common people but know the merit of its sterilization, hides the use of the sharp wind void of its account, remaining in all diseases with it, take effect repeatedly.”
Wine is the thing of sun heat, and honeysuckle taste is sweet cold in nature, fragrant odour, both clearly thoroughly can dredge table, can separate noxious heat in the blood system again.But too much unsuitable, honeysuckle too much can cause weakness of the spleen and the stomach.
Honeysuckle contains flavone compound, organic acid compound, volatile oil compound, triterpene saponin componds, trace element etc.
Flavonoids: cyanidenon, lonicerin, Hyperoside, Quercetin-3-O-β-D, cyanidenon-7-O-β-D-galactoside, cyanidenon-7-O-α-D, 5-hydroxyl-3 ', 4 ', 7-trimethyl flavones.
Organic acid: palmitic acid, caffeic acid, chlorogenic acid, isochlorogenic acid, myristic acid etc., wherein isochlorogenic acid is a mixture, there are 7 kinds of isomers, be respectively 5-asafoetide chinic acid, 4,5-bis-caffeic acid chinic acid, 4-asafoetide chinic acid, 3,5-bis-coffee-3-feruloyl quinic acids, 3,5-bis-caffeic acid acyl chinic acids, 3,4-bis-caffeic acid acyl chinic acid, 1,3-bis-caffeic acid acyl.
Volatile oil: volatile oil component has palmitic acid, linalool, 1,1-bicyclohexyl, octadecadienoic acid ethyl ester, tetracosa carbon acid methyl esters, dihydro carveol.
Triterpene saponin: asperosaponin second, largeflower-like honeysuckle flower saponin(e first, largeflower-like honeysuckle flower saponin(e second, 3-O-α-L-pyrans mouse wants glycosyl-(1 → 2)--L-arabopyranose base hederagenin-28-O-α-L-rhamnopyranosyl-(1 → 2)-[β-D-xylopyranosyl 2 (1 → 6)]-β-D-glucopyranosyl ester, 3-O-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabopyranose base hederagenin-28-O-β-D-xylopyranosyl-(1 → 6)-β-D-glucopyranosyl ester, 3-O-α-L-arabopyranose base hederagenin-28-O-α-L-rhamnopyranosyl-(1 → 2)-[β-D-xylopyranosyl 2 (1 → 6)] β-D-glucopyranosyl ester, 3-O-β-D-grape adjoins glycosyl of muttering (1 → 4)-β-D-glucopyanosyl base (1 → 3)-α-L-sandlwood pyrans glycosyl (1 → 2) α-L-arabopyranose base-Hederagenin Saponins unit-28-O-β-D-glucopyanosyl base (1 → 6)-β-D-glucopyanosyl base ester (F).
Trace element: Fe, Mn, Cu, Pb, V, Co, Li, Ca, Zn, Ti, Sr, Mo, Ba, Ni, Cr, K etc. totally 15 kinds, wherein K, Cr content is the highest.
Other: Organic Alcohol, sucrose, cupreol, β-daucosterol etc.
The step-down of honeysuckle energy, reduction serum cholesterol, increase CF, prevention coronary heart disease and angina cordis; Suppress the formation of cerebral thrombus; Improve human body resist oxygen lack free radical, strengthen memory, delay senility; Improve microcirculation, remove peroxidating fat deposition, enhance metabolism, moistening skin and eliminating spot.Chlorogenic acid compound can promote choleresis, has significant choleretic effect.
chinese cassia tree.hot in nature, taste is sweet, pungent, returns kidney, spleen, the heart, Liver Channel.There is benefit fire supporing yang, let the fire back to its origin, eliminating cold to stop pain, effect of activating blood to promote menstruation.Shennong's Herbal is recorded: " Your Majesty's gas is coughed inverse, and knot gas larynx numbness tells suction, sharp joint, tonifying middle-Jiao and Qi." " Mingyi Bielu " record: " main pained, side of body wind, hypochondriac pain, warm muscle, promotes blood circulation, only tired, perspiration." " in main temperature, benefitting liver and lung gas, trusted subordinate's fever and chills, cold disease, choleraic myospasm, headache, pain in the back, only saliva, cough ， Bi Weng: can have an abortion, hard joint, promoting blood circulation, reason is dredged not enough; A surname leads hundred medicines, without feared." " property of medicine opinion " record: " cure mainly: several pained, kill three worms, main broken blood, the tonneau moon closes, and controls weak foot, numbness, meciless, and placenta retension, inverse except coughing, knot gas, carbuncle numbness, only cold air in abdomen, unbearably painful, main diarrhea, nasal polyp.Herbicide wood poison." Compendium of Material Medica record: " control arthritis, wind Dumb, yin excess is lost blood, and rushes down dysentery, frightened dysentery." " control the deficiency of yang to lose blood, Neto ulcer variola, blood sweat can be drawn and suppurate, separate snake Pallas pit viper poison.”
Chinese cassia tree has the effect of flat liver, so-called wooden that osmanthus is then withered, and the pungent genus of taste is golden again, kind flat edema with the liver involved.When liver self-force quantity not sufficient, when can not dredging mechanism of qi, the property utilizing Chinese cassia tree hot enters Liver Channel with tonifying liver sun, reaches soothing the liver object by tonifying liver.Chinese cassia tree also can enter blood system and reach soothing the liver object.Liver is the viscus of storing blood, and right Chinese cassia tree can enter blood system and smooth blood, in this sense, and Chinese cassia tree promoting circulation of blood and soothing the liver.
The sweet heat of Chinese cassia tree and boosting source of fire for eliminating abundance of yin, simple and honestly solidifyingly to fall, can warm ying blood, and inspire qi and bloodization raw, can walk and can keep, the partially warm part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, can help again yang-energy in kidney, conducting the fire back to its origin.Sugariness can be mended, and pungent taste can fall apart and can manage it, therefore liver is warmed up in Chinese cassia tree tonifying spleen, warming kidney for dispelling cold, promoting circulation of blood and battalion, promoting blood circulation, Chinese cassia tree enters Hui Yang in the heart channel of Hang-Shaoyin energy temperature and promotes blood circulation, and enters the spleen channel warm spleen of energy and stomach, enter the warming liver and expelling cold of Liver Channel energy, enter lung channel and can take the photograph to receive and relieving asthma, enter kidney channel energy temperature compensating below element, Chinese cassia tree removes tool and mends fiery supporing yang, conducting the fire back to its origin, eliminating cold to stop pain, outside effect of temperature promoting blood circulation, another tool warming middle energizer to stop diarrhea, promoting blood circulation, it is inverse to rescue, stagnant with sunization, in sweet temperature compensation, the effect that assistant system is cold and cool.
Cassia bark is containing volatile oil, and its main component is cinnaldehydrum, acetic acid cassia bark ester, ethyl cinnamate, Ergol, benzaldehyde, coumarin, β-cadinene, calamus alkene, beta-elemene, protocatechuic acid, trans isomer cinnamic acid.Cassia bark is also containing 3 '-methyl-left-handed-epicatechin, 5,3 '-dimethyl-left-handed-epicatechin, 5,7,3 '-trimethoxy-left-handed-epicatechin, 4 '-methyl-D-cachou extract, 7,4 '-dimethyl-dextrorotation-cachou extract, 5,7,4 '-trimethyl-dextrorotation-cachou extract, left-handed-epicatechin-3-O-β-glycoside, left-handed-epicatechin-8-β-glycoside, left-handed-epicatechin-6-β-glycoside, left-handed-epicatechin, cassia bark tannin, former Cyanidin B 2-6-C-β-D-Glucose glucoside, Ceylon cinnamon element, cinnazeylanol, dehydration Ceylon cinnamon element, dehydration cinnazeylanol, the new alcohol of Chinese cassia tree, southern candelilla Syringaresinol-3 α-O-β-D-Glucose glucoside, 3,4,5-trimethoxy phenol-β-D-apiose (1 → 6)-β-D-Glucose glucoside, racemization-syringaresinol, 5,7-dimethyl-3 ', 4 '-dioxymethylene-racemization-epicatechin, cinnamic acid cyclic glycerol-1,3-acetal (9,2 '-trans), cinnamic acid cyclic glycerol-1,3-acetal (9,2 '-cis), cinnainoside, cinnamoside and cassia bark Polysaccharide A X.
Polyphenols in Chinese cassia tree has reduced form, can be oxidized to quinones.The superoxide radical in human body can be known, anti-lipid peroxidation thus protection liver.
Ketone in Chinese cassia tree can stimulate the spontaneous phosphorylation reaction of insulin receptor, promotes the absorption of glucose, the activity of Glycogen synthesis and glycogen transferase, suppresses fats sterol, glycogen also can be suppressed to transfer from one place to another under escort enzymatic activity, stimulates the synthesis of glycogen.
In prescription B, Poria cocos inducing diuresis with bland drug, long-pending disappearing of invigorating blood circulation, matrimony vine reaches irritability and loose stasis, and the soft liver emergency of sealwort, helps with wrinkled giant hyssop removing dampness to restore normal functioning of the stomach, with Chinese cassia tree promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, honeysuckle strengthening the spleen and replenishing qi, clearing heat and detoxicating for making.Full side focuses on and regulates the flow of vital energy, with pleasant machine, though containing the thing of regulating the flow of vital energy in a large number, mostly be gentle product.
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 28-42 part, matrimony vine 12-24 part, sealwort 8-20 part, wrinkled giant hyssop 2-12 part, honeysuckle 1-10 part, Chinese cassia tree 1-8 part;
As a kind of preferred technical scheme of the present invention, in described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 30-40 part, matrimony vine 14-22 part, sealwort 10-18 part, wrinkled giant hyssop 4-10 part, honeysuckle 2-8 part, Chinese cassia tree 1-6 part;
As a kind of preferred technical scheme of the present invention, in described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 32-38 part, matrimony vine 16-20 part, sealwort 12-16 part, wrinkled giant hyssop 6-8 part, honeysuckle 4-6 part, Chinese cassia tree 2-4 part.
honey
honey.property is put down, and taste is sweet, returns lung, spleen, large intestine channel.There is bowl spares, moisturize, pain relieving, effect of removing toxic substances.Compendium of Material Medica is recorded: " honey, its merit of being used as medicine has five: also, also, also, moisturize also, pain relieving also in removing toxic substances in bowl spares in heat-clearing.Raw then cool in nature, therefore can heat-clearing; Ripe then warm in nature, therefore energy bowl spares; Sweet and peaceful, therefore can detoxify; Soft and Ru Ze, therefore can moisturize; Delay and can go urgency, therefore trusted subordinate's muscle sore pain can be stopped; With can so that in, therefore can be in harmonious proportion hundred medicines and merit same with Radix Glycyrrhizae.Zhang Zhongjing Zhi Yangming ties dry, suffers from constipation, promoting defecation with honey suppository, and really eternal god side also." " Bencao Jingshu " record: " stone honey, its gas is cleer and peaceful, and its taste is pure sweet, the spiritual qi and blood executed, actual situation fever and chills, all diseases inside and outside negative and positive, deceives unsuitable." warp " is said: inner not enough person, with sweet benefit it." " same to pharagmitis rhizoma juice, pear juice, human milk, cattle and sheep breast, boys' urine, control dysphagic dry feces, moisten it with this, have phlegm to add bamboo juice.Cooked and all pills and ointment-like medicine for oral or plastering use, main moisturizing viscera, beneficial blood vessels, adjust spleen, stomach, and logical three is burnt.Be coated with the bright sore of fire and can delay pain." " medicine chemical industry " record: " essence of all sorts of flowers adopted by honey, the sweet main benefit of taste, nourishes the five internal organs, and the sliding main profit of body, moist three is burnt.As more than in timidity cough, essence and blood is withered, and the burnt leaf of lung is lifted, and cause into the disease of the dryness of the lung, fever and chills are all non-, the fresh effect of all medicines, and take two day perhaps with old honey, about the moon does not answer person, be the justice for the treatment of dryness syndrome by moistening also.Raw use tonneau large intestine, old constipation, more suitablely take it.”
Composition main in honey is sugar, inorganic salts, protein, amino acid, organic acid, trace element etc.
Carbohydrate: sucrose, fructose, glucose, gossypose, maltose, turanose, kojibiose etc., wherein topmost is sucrose, glucose, fructose, accounts for the 80%-90% of carbohydrate.
Enzyme: common are oxidizing ferment, amylase, invertase (invertase), reductase etc.Invertase and invertase can promote that carbohydate metabolism absorbs, and invertase can make the sucrose inversion in Bee Pollen be monose.Catalase has the effect of antioxidant radical, may be used for preventing body canceration and aging.
Acid compounds: amino acid, organic acid and inorganic acid.Amino acid is mainly histidine, arginine, lysine, threonine etc. 17 kinds, and total content is at about 0.1%-0.78%.Organic acid in honey is mainly gluconic acid and citric acid.Inorganic acid in honey is mainly hydrochloric acid, phosphoric acid, carbonic acid and boric acid etc.
Vitamins: vitamin C, vitamin B1, vitamin B2, vitamin B6, folic acid, nicotinic acid etc.In addition also containing pantothenic acid, thiamine, ascorbic acid, riboflavin etc.
Other: pigment, pollen, antibacterial material, wax etc.
Honey is from ancient times just by the food as invigorant and integration of drinking and medicinal herbs, and it has the effect of protection liver, cardiovascular system, also has protective effect to stomach, the disease of the nervous system disease and respiratory tract infection etc. is also had to the effect etc. helping cure.
Human body can not utilize liver and directly absorb amino acid, vitamin, monose and enzyme etc.; by chance contain a large amount of above-mentioned substances in honey; therefore; edible honey can strengthen the metabolism of human body; improve the storage capacity of glycogen; protection liver, is conducive to liver cell regeneration, can plays again the effect of prevention to the formation of fatty liver.
With parts by weight, contain in every 10000 parts of finished beverage:
Prescription A86-142 part
Prescription B52-116 part
Honey 300-500 part
White granulated sugar 150-300 part
Water surplus.
The compound method of described prescription A is:
(1) rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae washes clean will be weighed;
(2) filter extraction by after drug decocting 3-5 time after cleaning, the water yield at every turn added be the 6-8 of former dose doubly, extract and obtain separation and purification after extract.
As a kind of preferred technical scheme of the present invention, in the step (2) of the compound method of described prescription A, extraction temperature is 60-80 .This law adopts extraction heat, can extract more nutritional labeling under the condition of heating, but extraction temperature is unsuitable too high, and high temperature will destroy the structure of nutritional labeling.
The compound method of described prescription B is:
(1) pulverize after load weighted Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree washes clean;
(2) supercritical carbon dioxide extracting is used.
As a kind of preferred technical scheme of the present invention, in the step (2) of the compound method of described prescription B, extraction temperature is 30-35 , extracting pressure is 18-25MPa, and resolution temperature is 42-53 , parsing pressure is 5-7MPa.
Supercritical carbon dioxide extraction method (SFE-CO 2) have that Extracting temperature is low, recovery rate is high, solvent load is few and without advantages such as the three wastes, be a kind of eco-friendly extracting method.Pulverize after load weighted Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree washes clean, load extraction kettle, at temperature 30-35 extract 2-4h with under the condition of pressure 18-25MPa, resolution temperature is set to 42-53 , parsing pressure is 5-7MPa, merges extract, mixes, obtain prescription B.
The present invention also provides a kind of method preparing anti-alcohol and liver-protection beverage, and described preparation method is:
(1) by heating for dissolving after the mixing of prescription A, prescription B and water;
(2) be cooled to room temperature, add honey, white granulated sugar, filtration, sterilization, filling, to obtain final product.
Described filtration use 120 mesh sieve, also containing a small amount of natural products precipitation in the product after filtration.High temperature, short time (HTST) method for disinfection is selected in described sterilization, and parameter is 95 time keep 30s.Described filling vacuum filling machine of selecting is filling, and filling vacuum is 600-720 millimetres of mercury.
Embodiment
Table 1 is the parts by weight of each material composition in prescription A, and table 2 is the parts by weight of each material composition in prescription B.Table 3 is content of material composition in embodiment.
Table 1
Table 2
Table 3
Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Example 9 Example 10 Example 11 Example 12
A1 86 86 98
A2 142
A3 98
A4 132
A5 108
A6 122 122
A7 115 115 115
B1 52 52
B2 116 116 116
B3 61
B4 104 104
B5 72
B6 92
B7 82 82
White granulated sugar 300 320 340 360 380 400 420 440 460 480 500 380
Honey 150 165 180 195 210 225 240 255 270 285 300 210
Water Surplus Surplus Surplus Surplus Surplus Surplus Surplus Surplus Surplus Surplus Surplus Surplus
evaluation method
(1) ethanol in blood concentration
Get small white mouse 40, each 20 of male and female, are divided into 5 groups at random, often organize 4.1st group and the 2nd group of perfusion physiological saline 0.2mL/10g body weight, 3-5 group pours into the anti-alcohol and liver-protection beverage 0.2mL/10g body weight of embodiment 1-3 respectively.After 30min, the 1st group of gavage physiological saline 0.2mL/10g body weight, 2-5 group gavage 0.2mL/10g body weight.To often organizing small white mouse venous blood samples 0.3mL after 30min, 60min, 90min, 120min after gavage white wine, then adding 3mL200g/L trichloroacetic acid, adding deionized water and being diluted to 25mL.Get supernatant after centrifugal to measure.Measure ethanol content with GC-External Standard method, result is as shown in table 4.
Chromatographic condition: Shimadzu GC-2014C, capillary column Rxi-17, injector temperature 150 , column temperature 180 , detector 180 , N 2flow velocity 50mL/min, H 2flow velocity 25mL/min, air velocity 25mL/min, sampling volume .
Table 4
(2) animal's liver Pathological experiment
Get small white mouse 50, each 25 of male and female, are divided into 5 groups at random, often organize 10.Normally feed 7 days for 1st group.2nd group continuous 7 day every day per os 0.2mL/10g body weight; 3rd group continuous 7 day every day per os 0.1mL embodiment 4, then per os 0.2mL/10g body weight; 4th group continuous 7 day every day per os 0.2mL embodiment 5, then per os 0.2mL/10g body weight; 5th group continuous 7 day every day per os 0.3mL embodiment 6, then per os 0.2mL/10g body weight.After administration in the 7th day, put to death small white mouse, eye socket gets the content of hematometry serum glutamic pyruvic transminase, and result, as table 5, is separately got partial liver and carried out pathological examination.
Table 5
Pathological tissue finds, the 1st group of hepatic cell cords arrangement is regular, and cell size is normal, and chest slurry is slightly loose; 2nd group exists lobuli hepatis, and hepatic cell cords arrangement is substantially regular, liver cell obvious tumefaction, and endochylema is loose, light dye, change in granular.The above situation of 3-5 group takes a turn for the better all to some extent, and the 5th group close with the 1st group.
(3) alcohol tester
10 volunteers drink 100mL after, 1 st volunteer does not drink anti-alcohol and liver-protection beverage of the present invention, and 2-10 st volunteer drinks the beverage of embodiment 7-12, tests, the results are shown in Table 6 after 30min with alcohol tester.
Table 6
Above-mentioned data show, according to the anti-alcohol and liver-protection beverage that the present invention obtains, effectively can reduce the concentration of alcohol in blood.The serum glutamic pyruvic transminase content that hepatic injury caused by ethanol can cause raises, and anti-alcohol and liver-protection beverage provided by the present invention can repair liver cell.Volunteer drinks described anti-alcohol and liver-protection beverage can reduce the malaise symptoms of drinking and occurring, this beverage can also be used for the pre-preventing drunkenness of the crowd of drinking and treatment drunk person.Drink in wine before wine, capacity for liquor can be made to double.Drink after drinking can alleviate uncomfortable after drinking.Also can hindered alcohol to the injury of liver, help liver detoxification, repair wounded hepatocytes.
The above; be only the present invention's preferably specific embodiment; but protection scope of the present invention is not limited thereto; anyly be familiar with those skilled in the art in the scope that the present invention discloses; be equal to according to technical scheme of the present invention and inventive concept and replace or change, all belonged to protection scope of the present invention.

Claims (10)

1. an anti-alcohol and liver-protection beverage, is characterized in that,
(1) prescription A and prescription B is comprised;
(2) extract consisting of following material of described prescription A: rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae;
(3) extract consisting of following material of described prescription B: Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree;
Described anti-alcohol and liver-protection beverage also comprises honey, white granulated sugar and water.
2. anti-alcohol and liver-protection beverage as claimed in claim 1, is characterized in that,
In described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 32-44 part, hawthorn 24-36 part, root of kudzu vine 20-32 part, dark plum 6-16 part, Radix Glycyrrhizae 4-14 part;
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 28-42 part, matrimony vine 12-24 part, sealwort 8-20 part, wrinkled giant hyssop 2-12 part, honeysuckle 1-10 part, Chinese cassia tree 1-8 part.
3. anti-alcohol and liver-protection beverage as claimed in claim 1, is characterized in that,
In described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 36-42 part, hawthorn 26-34 part, root of kudzu vine 22-30 part, dark plum 8-14 part, Radix Glycyrrhizae 6-12 part;
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 30-40 part, matrimony vine 14-22 part, sealwort 10-18 part, wrinkled giant hyssop 4-10 part, honeysuckle 2-8 part, Chinese cassia tree 1-6 part.
4. anti-alcohol and liver-protection beverage as claimed in claim 1, is characterized in that,
In described prescription A, the parts by weight of the extract of each material in this prescription are:
Rhodiola root 38-40 part, hawthorn 28-32 part, root of kudzu vine 24-28 part, dark plum 10-12 part, Radix Glycyrrhizae 8-10 part;
In described prescription B, the parts by weight of the extract of each material in this prescription are:
Poria cocos 32-38 part, matrimony vine 16-20 part, sealwort 12-16 part, wrinkled giant hyssop 6-8 part, honeysuckle 4-6 part, Chinese cassia tree 2-4 part.
5. anti-alcohol and liver-protection beverage as claimed in claim 1, is characterized in that, with parts by weight, contain in every 10000 parts of finished beverage:
Prescription A86-142 part
Prescription B52-116 part
Honey 300-500 part
White granulated sugar 150-300 part
Water surplus.
6. anti-alcohol and liver-protection beverage as claimed in claim 1, it is characterized in that, the compound method of described prescription A is:
(1) rhodiola root, hawthorn, the root of kudzu vine, dark plum, Radix Glycyrrhizae washes clean will be weighed;
(2) filter extraction by after drug decocting 3-5 time after cleaning, the water yield at every turn added be the 6-8 of former dose doubly, extract and obtain separation and purification after extract.
7. anti-alcohol and liver-protection beverage as claimed in claim 6, it is characterized in that, in the step (2) of the compound method of described prescription A, extraction temperature is 60-80 .
8. anti-alcohol and liver-protection beverage as claimed in claim 1, it is characterized in that, the compound method of described prescription B is:
(1) pulverize after load weighted Poria cocos, matrimony vine, sealwort, wrinkled giant hyssop, honeysuckle, Chinese cassia tree washes clean;
(2) supercritical carbon dioxide extracting is used.
9. anti-alcohol and liver-protection beverage as claimed in claim 8, it is characterized in that, in the step (2) of the compound method of described prescription B, extraction temperature is 30-35 , extracting pressure is 18-25MPa, and resolution temperature is 42-53 , parsing pressure is 5-7MPa.
10. prepare a method for the anti-alcohol and liver-protection beverage any one of claim 1-9 as described in claim, it is characterized in that, described preparation method is:
(1) by heating for dissolving after the mixing of prescription A, prescription B and water;
(2) be cooled to room temperature, add honey, white granulated sugar, filtration, sterilizing, filling, to obtain final product.
CN201510764882.3A 2015-11-11 2015-11-11 A kind of anti-alcohol and liver-protection beverage and preparation method thereof Expired - Fee Related CN105380051B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510764882.3A CN105380051B (en) 2015-11-11 2015-11-11 A kind of anti-alcohol and liver-protection beverage and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510764882.3A CN105380051B (en) 2015-11-11 2015-11-11 A kind of anti-alcohol and liver-protection beverage and preparation method thereof

Publications (2)

Publication Number Publication Date
CN105380051A true CN105380051A (en) 2016-03-09
CN105380051B CN105380051B (en) 2018-10-16

Family

ID=55413307

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510764882.3A Expired - Fee Related CN105380051B (en) 2015-11-11 2015-11-11 A kind of anti-alcohol and liver-protection beverage and preparation method thereof

Country Status (1)

Country Link
CN (1) CN105380051B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106070931A (en) * 2016-07-06 2016-11-09 吉林省黑翠农业发展有限公司 A kind of Semen Maydis making coffee beverage and preparation method
CN106235235A (en) * 2016-07-28 2016-12-21 武汉黄鹤楼香精香料有限公司 A kind of essence of energy relieving alcoholism and protecting the liver and preparation method thereof
CN106262823A (en) * 2016-08-12 2017-01-04 张彦优 A kind of alcohol-neutralize healthy product
CN106387567A (en) * 2016-08-29 2017-02-15 王士学 Traditional Chinese medicine beverage and making method thereof
CN106472924A (en) * 2016-09-28 2017-03-08 黔南民族师范学院 A kind of anti-alcohol and liver-protection beverage and preparation method thereof
CN106962698A (en) * 2017-03-03 2017-07-21 江苏康缘药业股份有限公司 A kind of composition, beverage and preparation method thereof
CN109170038A (en) * 2018-08-06 2019-01-11 合肥志诚蜂业有限责任公司 It is a kind of to sober up and alleviate the honey energy drinks having a headache after drinking
CN110669632A (en) * 2019-10-12 2020-01-10 天津科技大学 Anti-alcohol vinegar rich in probiotics and preparation method and application thereof
CN115052490A (en) * 2020-03-31 2022-09-13 株式会社东洋新药 Oral composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0614746A (en) * 1992-06-29 1994-01-25 Oomiya Yakugyo Kk Health beverage
CN101455354A (en) * 2007-12-14 2009-06-17 中国科学院微生物研究所 Natural Juncao liver-nourishing and sobering-up agent
CN104248013A (en) * 2014-08-13 2014-12-31 金新凯 Plant drink formula
CN104286287A (en) * 2014-08-18 2015-01-21 湘潭市明府养生茶业有限公司 Anti-alcohol tea and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0614746A (en) * 1992-06-29 1994-01-25 Oomiya Yakugyo Kk Health beverage
CN101455354A (en) * 2007-12-14 2009-06-17 中国科学院微生物研究所 Natural Juncao liver-nourishing and sobering-up agent
CN104248013A (en) * 2014-08-13 2014-12-31 金新凯 Plant drink formula
CN104286287A (en) * 2014-08-18 2015-01-21 湘潭市明府养生茶业有限公司 Anti-alcohol tea and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
古今等: "解酒药物的研究进展", 《中国药物应用与监测》 *
吴吉琳: "《100道人气煲汤》", 31 March 2015, 湖北科学技术出版社 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106070931A (en) * 2016-07-06 2016-11-09 吉林省黑翠农业发展有限公司 A kind of Semen Maydis making coffee beverage and preparation method
CN106235235A (en) * 2016-07-28 2016-12-21 武汉黄鹤楼香精香料有限公司 A kind of essence of energy relieving alcoholism and protecting the liver and preparation method thereof
CN106262823A (en) * 2016-08-12 2017-01-04 张彦优 A kind of alcohol-neutralize healthy product
CN106387567A (en) * 2016-08-29 2017-02-15 王士学 Traditional Chinese medicine beverage and making method thereof
CN106472924A (en) * 2016-09-28 2017-03-08 黔南民族师范学院 A kind of anti-alcohol and liver-protection beverage and preparation method thereof
CN106962698A (en) * 2017-03-03 2017-07-21 江苏康缘药业股份有限公司 A kind of composition, beverage and preparation method thereof
CN109170038A (en) * 2018-08-06 2019-01-11 合肥志诚蜂业有限责任公司 It is a kind of to sober up and alleviate the honey energy drinks having a headache after drinking
CN110669632A (en) * 2019-10-12 2020-01-10 天津科技大学 Anti-alcohol vinegar rich in probiotics and preparation method and application thereof
CN115052490A (en) * 2020-03-31 2022-09-13 株式会社东洋新药 Oral composition

Also Published As

Publication number Publication date
CN105380051B (en) 2018-10-16

Similar Documents

Publication Publication Date Title
CN105380051B (en) A kind of anti-alcohol and liver-protection beverage and preparation method thereof
CN102273639B (en) Nidus collocaliae perfume (or spice) system product and preparation method thereof
CN104799146A (en) Functional nutritional good composition for improving sub-health and preparation method thereof
CN102573871A (en) Antiphlogistic, antioncotic and analgesic chinese herbal composition,preparative method and usage thereof
KR100968109B1 (en) Calcium?compound containing natural product composition for curing a hangover and preparation method thereof
CN102698137B (en) Composition with blood pressure reducing function and preparation method of same
CN109700968A (en) It is a kind of with boosting qi and nourishing yin, the Chinese medicine composition of anti-fatigue effect and preparation method thereof
CN103610803A (en) Traditional Chinese medicine composition for protecting liver and dispelling effects of alcohol
CN102273679A (en) Preparation method of beverage
CN103933509B (en) For treating medicine of fresh-water fishes fish molds and preparation method thereof
CN104815192A (en) Pharmaceutical composition for treating hypertension and application of pharmaceutical composition
CN104306659B (en) A kind of Chinese medicine composition for treating diabetes B
CN108813501A (en) With the relieving cough and reducing sputum health honey paste relievingd asthma and adjust function of human body of clearing heat and moistening lung
CN104161977B (en) It is a kind of to be used to prevent and treat Chinese medicine composition of infectious coryza of chicken and preparation method thereof
CN102727761A (en) Medicine for treating alopecia seborrheica and preventing hair drying and bifurcating and method for preparing medicine
CN100577193C (en) Health product for sobering-up
CN103520302B (en) Sea-buckthorn leaf anti-fatigue capsule and preparation method thereof
Chillemi The complete guide to natural healing: a natural approach to healing the body and maintaining optimal health using herbal supplements, vitamins, minerals, fruits, vegetables and alternative medicine
CN103007145B (en) Traditional Chinese medicine composition for treating children rotavirus enteritis and preparation method of composition
CN105617268A (en) Medicine for treating scale keratinization type beriberi
CN110522798A (en) A kind of compound preparation and preparation method thereof curing mainly coronary heart disease
KR20170024689A (en) Food composition for bowel movement promotion and diet using herbal material
KR101068128B1 (en) Natural product composition containing ionized calcium fertilized unmilled rice for activating alcohol excretion,aldehyde metabolism and curing a hangover and preparation method thereof
CN107596247A (en) A kind of anaesthetic and its manufacturing process for treating tuberculosis
CN109289017A (en) For clearing up the composition and preparation method of blood vessel and blood

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information

Address after: 810003 403, 4 building, 26 Road four, Chengbei District, Xining, Qinghai.

Applicant after: Nine Yin Tang Biotechnology Co., Ltd.

Address before: 810003 403, 4 building, 26 Road four, Chengbei District, Xining, Qinghai.

Applicant before: QINGHAI GANLUYIN BIOTECHNOLOGY CO., LTD.

CB02 Change of applicant information
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20181016

Termination date: 20191111

CF01 Termination of patent right due to non-payment of annual fee