CN105377246B - 针对非酒精性脂肪性肝病(nafld)的新组合物 - Google Patents

针对非酒精性脂肪性肝病(nafld)的新组合物 Download PDF

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Publication number
CN105377246B
CN105377246B CN201380075905.9A CN201380075905A CN105377246B CN 105377246 B CN105377246 B CN 105377246B CN 201380075905 A CN201380075905 A CN 201380075905A CN 105377246 B CN105377246 B CN 105377246B
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use according
sodium
fatty liver
formula
liver
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CN105377246A (zh
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潘卡杰·帕特尔
亚尼 拉金德拉库马尔·哈里普拉萨德
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Zadusi Life Sciences Co ltd
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Cadila Healthcare Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN201380075905.9A 2013-04-22 2013-06-25 针对非酒精性脂肪性肝病(nafld)的新组合物 Active CN105377246B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1468/MUM/2013 2013-04-22
IN1468MU2013 IN2013MU01468A (https=) 2013-04-22 2013-06-25
PCT/IN2013/000391 WO2014174524A1 (en) 2013-04-22 2013-06-25 A novel composition for nonalcoholic fatty liver disease (nafld)

Publications (2)

Publication Number Publication Date
CN105377246A CN105377246A (zh) 2016-03-02
CN105377246B true CN105377246B (zh) 2018-03-20

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CN201380075905.9A Active CN105377246B (zh) 2013-04-22 2013-06-25 针对非酒精性脂肪性肝病(nafld)的新组合物

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US (3) US20160166539A1 (https=)
EP (1) EP2988736A1 (https=)
JP (1) JP6246895B2 (https=)
KR (1) KR101617812B1 (https=)
CN (1) CN105377246B (https=)
AP (1) AP2015008674A0 (https=)
AU (1) AU2013387996B2 (https=)
BR (1) BR112015020600A2 (https=)
CA (1) CA2900435C (https=)
EA (1) EA201592020A1 (https=)
GE (1) GEP201706663B (https=)
HK (1) HK1214968A1 (https=)
IL (2) IL240183A (https=)
IN (1) IN2013MU01468A (https=)
MA (1) MA38385A1 (https=)
MX (1) MX346943B (https=)
MY (1) MY180160A (https=)
PH (1) PH12015501795A1 (https=)
SG (1) SG11201506218UA (https=)
UA (1) UA114360C2 (https=)
WO (1) WO2014174524A1 (https=)

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US10385017B2 (en) 2015-10-14 2019-08-20 Cadila Healthcare Limited Pyrrole compound, compositions and process for preparation thereof
CN117137917A (zh) * 2016-04-22 2023-12-01 景凯生物科技股份有限公司 纳美芬、纳曲酮或其衍生物在治疗(非)酒精性脂肪肝炎或非酒精性脂肪性肝病的应用
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GB201710229D0 (en) 2017-06-27 2017-08-09 Tdeltas Ltd Compounds for new use
US10980810B2 (en) * 2017-10-06 2021-04-20 Gilead Sciences, Inc. Combination therapy comprising an ACC inhibitor
CN109675016A (zh) * 2017-10-18 2019-04-26 上海贺普药业股份有限公司 非酒精性脂肪性肝病的治疗药物
CN110934866B (zh) * 2018-09-25 2023-12-01 深圳微芯生物科技股份有限公司 西格列羧及其相关化合物的应用
US12201609B2 (en) * 2018-12-18 2025-01-21 Zydus Lifesciences Limited Saroglitazar for the treatment of hepatocellular carcinoma
EP3923932A4 (en) * 2019-02-13 2022-11-16 Cadila Healthcare Limited Treatment for polycystic ovarian syndrome (pcos)
WO2022128870A1 (en) * 2020-12-18 2022-06-23 Société des Produits Nestlé S.A. Compositions and methods using at least one glycine or derivative thereof and/or at least one n-acetylcysteine or derivative thereof, and at least one thymol and/or carvacrol
WO2022246243A1 (en) * 2021-05-21 2022-11-24 HepQuant, LLC Methods of defining functional change and slowing progression in chronic liver disease
WO2025238663A1 (en) * 2024-05-16 2025-11-20 Zydus Lifesciences Limited Saroglitazar for the treatment of alcoholic liver diseases

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IL240183A0 (en) 2015-09-24
US20160166539A1 (en) 2016-06-16
CA2900435C (en) 2017-02-14
MY180160A (en) 2020-11-23
AU2013387996A1 (en) 2015-09-24
MA38385A1 (fr) 2017-09-29
UA114360C2 (uk) 2017-05-25
IL247231A (en) 2017-03-30
CN105377246A (zh) 2016-03-02
JP2016515608A (ja) 2016-05-30
IL240183A (en) 2016-08-31
PH12015501795A1 (en) 2015-11-09
MX346943B (es) 2017-04-06
MX2015010769A (es) 2015-11-26
US20180185330A1 (en) 2018-07-05
BR112015020600A2 (pt) 2017-07-18
KR20150118990A (ko) 2015-10-23
WO2014174524A8 (en) 2015-10-01
CA2900435A1 (en) 2014-10-30
US9814697B2 (en) 2017-11-14
GEP201706663B (en) 2017-05-10
KR101617812B1 (ko) 2016-05-03
JP6246895B2 (ja) 2017-12-13
WO2014174524A1 (en) 2014-10-30
IN2013MU01468A (https=) 2015-04-17
EA201592020A1 (ru) 2016-05-31
US20170087127A1 (en) 2017-03-30
AP2015008674A0 (en) 2015-08-31
EP2988736A1 (en) 2016-03-02
SG11201506218UA (en) 2015-09-29
HK1214968A1 (zh) 2016-08-12
AU2013387996B2 (en) 2015-12-10

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Address after: India, Gujarat

Patentee after: Zadusi Life Sciences Co.,Ltd.

Address before: India, Gujarat

Patentee before: CADILA HEALTHCARE Ltd.