CN105362858A - Pharmaceutical for treating chronic bronchitis - Google Patents
Pharmaceutical for treating chronic bronchitis Download PDFInfo
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- CN105362858A CN105362858A CN201510838985.XA CN201510838985A CN105362858A CN 105362858 A CN105362858 A CN 105362858A CN 201510838985 A CN201510838985 A CN 201510838985A CN 105362858 A CN105362858 A CN 105362858A
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Abstract
The invention discloses a pharmaceutical for treating chronic bronchitis and belongs to the technical field of traditional Chinese medicine. The pharmaceutical is prepared from Radix Stemonae, Herba Serissae Japonicae, Bulbus Fritillariae Cirrhosae, Herba Hyperici Japonici, Radix Adenophorae, Pericarpium Citri Reticulatae, Herba Senecionis Scandentis, Semen Armeniacae, Poria, Rhizoma Atractylodis, Cortex Magnoliae Officinalis and Radix Actinidiae Valvatae. The pharmaceutical has a scientific and reasonable formula, the herbs are synergistic, allowing the pharmaceutical to be effective in moistening lung to arrest cough, clearing heat and toxicity, invigorating spleen to remove dampness, and regulating qi for eliminating phlegm, and the pharmaceutical is well effective in treating chronic bronchitis and is low cost, free of recurrence and is safe without side effect.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of chronic bronchitis, belong to technical field of Chinese medicines.
Background technology
Chronic bronchitis is a kind of commonly encountered diseases of respiratory system, is the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue.Clinical with cough, expectoration for cardinal symptom, annual morbidity continues 3 months, continuous more than 2 years or 2 years.This disease can recurrent exerbation, makes bronchus and alveolar structure and function that a series of change occur.Cause obstructive emphysema, pulmonary heart disease etc.Chronic bronchitis sickness rate is very high, particularly the frequently-occurring disease in rural area, and in the majority with late adult onset, serious harm health of people.Although have some to be used for the treatment of the Chinese and western drugs of chronic bronchitis at present, some consumption cost is higher, adds patient burden, and the curative effect of medicine is also not satisfactory in addition, and easily recurs.
Summary of the invention
For problems of the prior art, the invention provides a kind of medicine for the treatment of chronic bronchitis.This pharmaceutical formulation is reasonable, and drug effect is remarkable, and have cost to the treatment of chronic bronchitis low, curative effect is high, the feature that safety has no side effect.
The present invention is by the following technical solutions:
A kind of medicine for the treatment of chronic bronchitis, it is characterized in that, it comprises the crude drug of following weight portion: Radix Stemonae 3-8 part, Serissa foetida 10-20 part, Bulbus Fritillariae Cirrhosae 15-25 part, Herba Hyperici Japonici 6-15 part, Radix Adenophorae (Radix Glehniae) 8-15 part, Pericarpium Citri Reticulatae 20-30 part, Herba Senecionis Scandentis 20-30 part, Semen Armeniacae Amarum 6-10 part, Poria 20-30 part, Rhizoma Atractylodis 10-20 part, Cortex Magnoliae Officinalis 3-8 part, Radix actinidiae valvatae 3-8 part.
Preferred as one of the present invention, described medicine comprises the crude drug of following weight portion: the Radix Stemonae 6 parts, Serissa foetida 16 parts, Bulbus Fritillariae Cirrhosae 20 parts, Herba Hyperici Japonici 12 parts, Radix Adenophorae (Radix Glehniae) 12 parts, Pericarpium Citri Reticulatae 25 parts, Herba Senecionis Scandentis 25 parts, 8 parts, Semen Armeniacae Amarum, 25 parts, Poria, Rhizoma Atractylodis 15 parts, Cortex Magnoliae Officinalis 5 parts, Radix actinidiae valvatae 5 parts.
The preparation method of medicine of the present invention is as follows:
Get formula ratio raw medicinal material, suitably chopping or pulverizing, put and be suitable for decocting in container, add 1000-1200ml water logging and do not have medical material, soak after 1.5-2 hour, be heated to boiling, then be separated fried liquid after decocting 30 minutes, add 800ml water in medicinal residues more fried 2-3 time in accordance with the law, collect each fried liquid and mix post-heating and be concentrated into 600ml and get final product.
Drug usage of the present invention and consumption: decocting is oral, one day three times, a 200ml, took early, middle and late half an hour after meal.Within 7 days, be 1 course for the treatment of, general 3-5 can fully recover a course for the treatment of.
Formula pharmacological action of the present invention is as follows:
The Radix Stemonae: sweet in the mouth, hardship, slightly warm in nature.Return lung meridian.There is nourishing the lung to keep the adverse QI downward cough-relieving, effect of parasite killing delousing.
Serissa foetida: light, micro-pungent, cool.There is invigorating spleen to remove dampness, effect that soothing liver-QI is invigorated blood circulation.
Bulbus Fritillariae Cirrhosae: bitter in the mouth, sweet, cold nature.Return lung, heart channel.There are clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, effect of eliminating stagnation eliminating carbuncle.
Herba Hyperici Japonici: sweet, bitter, cold.Return lung, liver, stomach warp.There is clearing away heat-damp and promoting diuresis, removing toxic substances, effect of dissipating blood stasis for subsidence of swelling.
Radix Adenophorae (Radix Glehniae): sweet in the mouth, micro-hardship, cold nature.Return lung, stomach warp.There is clearing away heat and nourishing YIN, effect of nourishing the lung to arrest cough.
Pericarpium Citri Reticulatae: bitter in the mouth, pungent, warm in nature.Return lung, spleen channel.There is regulating qi-flowing for strengthening spleen, effect of drying dampness to eliminate phlegm.
Herba Senecionis Scandentis: cold in nature, bitter in the mouth.Return lung, Liver Channel.There is heat-clearing and toxic substances removing, improving eyesight, antipruritic effect.
Semen Armeniacae Amarum: bitter, temperature.Enter lung, large intestine channel.There is expelling phlegm for arresting cough, relieving asthma, effect of intestine moistening.
Poria: sweet, light is flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, effect of spleen invigorating mind calming.
Rhizoma Atractylodis: pungent, bitter, temperature.Return spleen, stomach, Liver Channel.Have drying damp and strengthening spleen, expelling wind and cold, effect of improving eyesight.
Cortex Magnoliae Officinalis: bitter, pungent, temperature.Return spleen, stomach, lung, large intestine channel.Have dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full effect.
Radix actinidiae valvatae: bitter, puckery, cool.Return Liver Channel.There is effect of heat-clearing and toxic substances removing.
Chinese medicine claims primary disease to be " phlegm retention ", cough with asthma etc., recurrent exerbation and not healing, may be relevant to lung, spleen, two kidney.If disease does not heal for a long time, namely can occur " deficiency in origin and excess in superficiality, it is marked on lung, the fundamental cause of water disease being in the kidney ".The present inventor is according to clinical experience and the research to pharmacodynamics for many years, and sum up formula of the present invention, this prescription drug is scientific and reasonable, and all medicine synergism, have effect of nourishing the lung to arrest cough, heat-clearing and toxic substances removing, invigorating the spleen to clear away damp pathogen, activating QI to eliminate phlegm.
The invention has the beneficial effects as follows: medicine of the present invention is good to the therapeutic effect of chronic bronchitis, and cost is low, without recurrence, safety has no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1
Treat a medicine for chronic bronchitis, it comprises the crude drug of following weight portion: the Radix Stemonae 3 parts, Serissa foetida 10 parts, Bulbus Fritillariae Cirrhosae 15 parts, Herba Hyperici Japonici 6 parts, Radix Adenophorae (Radix Glehniae) 8 parts, Pericarpium Citri Reticulatae 20 parts, Herba Senecionis Scandentis 20 parts, 6 parts, Semen Armeniacae Amarum, 20 parts, Poria, Rhizoma Atractylodis 10 parts, Cortex Magnoliae Officinalis 3 parts, Radix actinidiae valvatae 3 parts.
The preparation method of said medicine is as follows:
Get formula ratio raw medicinal material, suitably chopping or pulverizing, put and be suitable for decocting in container, add 1000-1200ml water logging and do not have medical material, soak after 1.5-2 hour, be heated to boiling, then be separated fried liquid after decocting 30 minutes, add 800ml water in medicinal residues more fried 2-3 time in accordance with the law, collect each fried liquid and mix post-heating and be concentrated into 600ml and get final product.
Embodiment 2
Treat a medicine for chronic bronchitis, it comprises the crude drug of following weight portion: the Radix Stemonae 8 parts, Serissa foetida 20 parts, Bulbus Fritillariae Cirrhosae 25 parts, Herba Hyperici Japonici 15 parts, Radix Adenophorae (Radix Glehniae) 15 parts, Pericarpium Citri Reticulatae 30 parts, Herba Senecionis Scandentis 30 parts, 10 parts, Semen Armeniacae Amarum, 30 parts, Poria, Rhizoma Atractylodis 20 parts, Cortex Magnoliae Officinalis 8 parts, Radix actinidiae valvatae 8 parts.
The preparation method of said medicine is with embodiment 1.
Embodiment 3
Treat a medicine for chronic bronchitis, it comprises the crude drug of following weight portion: the Radix Stemonae 6 parts, Serissa foetida 16 parts, Bulbus Fritillariae Cirrhosae 20 parts, Herba Hyperici Japonici 12 parts, Radix Adenophorae (Radix Glehniae) 12 parts, Pericarpium Citri Reticulatae 25 parts, Herba Senecionis Scandentis 25 parts, 8 parts, Semen Armeniacae Amarum, 25 parts, Poria, Rhizoma Atractylodis 15 parts, Cortex Magnoliae Officinalis 5 parts, Radix actinidiae valvatae 5 parts.
The preparation method of said medicine is with embodiment 1.
In order to further illustrate the drug effect of medicine of the present invention, be specifically described below in conjunction with concrete clinical data.
1. clinical data: choose chronic bronchitis patient 268 example that outpatient service to be accepted for medical treatment in January, 2013 ~ 2014 year June, wherein male 149 example, women 119 example; The oldest 82 years old, minimum 58 years old.
2. diagnostic criteria: (1) cough, expectoration or companion pant, annual morbidity 3 months, continuous 2 years or more persons.(2) fall ill less than 3 months every year, and have clear and definite objective determination also diagnosable according to (as x-ray, lung function tests etc.) person.(3) other hearts, lung disease (as pulmonary tuberculosis, asthma, bronchiectasis, pulmonary carcinoma, heart disease etc.) person can be got rid of.
3. Therapeutic Method: all cases take medicine of the present invention, and decocting is oral, one day three times, a 200ml, took early, middle and late half an hour after meal.7 days was 1 course for the treatment of, observed therapeutic effect after taking 3-5 the course for the treatment of.
4. curative effect determinate standard:
Cure: clinical cough, cough up phlegm, to pant and the symptom such as pulmonary's wheezing sound all disappears, follow-up observation 1 year is without recidivist;
Effective: clinical cough, to cough up phlegm, to pant and the symptom such as pulmonary's wheezing sound obviously alleviates;
Take a turn for the better: clinical cough, cough up phlegm and to pant and the symptom such as pulmonary's wheezing sound alleviates to some extent;
Invalid: clinical cough, cough up phlegm, pant and the symptom such as pulmonary's wheezing sound without improvement or add severe one on the contrary.
5. therapeutic outcome:
268 routine chronic bronchitis patients, after clinical treatment, are cured 198 examples, are accounted for 73.9%; Effective 45 examples, account for 16.8%; Take a turn for the better 23 examples, accounts for 8.6%; Invalid 2 examples, account for 0.7%; Total effective rate is 99.3%.
The long-term toxicity test for animals of medicine of the present invention
Get rat 20, body weight 200-250g, divide two groups, often organize 10, wherein one group is overdose test group, and another group is normal amount test group.Super quantity group is 30ml/ days, and normal amount is 10ml/ days, and administering mode is gastric infusion, once a day, continuous use 60 days, observe administration reaction every day, result shows that two groups of rat bodies are without poisoning generation, normally, body weight slightly increases, and medicine is without bad toxic and side effects for activity, diet.
In sum, the curative effect of medication for the treatment of chronic bronchitis of the present invention is high, safety without any side effects, and more after not easily recur, be the choice drug of vast chronic bronchitis patient.
Claims (2)
1. treat the medicine of chronic bronchitis for one kind, it is characterized in that, it comprises the crude drug of following weight portion: Radix Stemonae 3-8 part, Serissa foetida 10-20 part, Bulbus Fritillariae Cirrhosae 15-25 part, Herba Hyperici Japonici 6-15 part, Radix Adenophorae (Radix Glehniae) 8-15 part, Pericarpium Citri Reticulatae 20-30 part, Herba Senecionis Scandentis 20-30 part, Semen Armeniacae Amarum 6-10 part, Poria 20-30 part, Rhizoma Atractylodis 10-20 part, Cortex Magnoliae Officinalis 3-8 part, Radix actinidiae valvatae 3-8 part.
2. medicine according to claim 1, it is characterized in that, it comprises the crude drug of following weight portion: the Radix Stemonae 6 parts, Serissa foetida 16 parts, Bulbus Fritillariae Cirrhosae 20 parts, Herba Hyperici Japonici 12 parts, Radix Adenophorae (Radix Glehniae) 12 parts, Pericarpium Citri Reticulatae 25 parts, Herba Senecionis Scandentis 25 parts, 8 parts, Semen Armeniacae Amarum, 25 parts, Poria, Rhizoma Atractylodis 15 parts, Cortex Magnoliae Officinalis 5 parts, Radix actinidiae valvatae 5 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510838985.XA CN105362858A (en) | 2015-11-27 | 2015-11-27 | Pharmaceutical for treating chronic bronchitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510838985.XA CN105362858A (en) | 2015-11-27 | 2015-11-27 | Pharmaceutical for treating chronic bronchitis |
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| CN105362858A true CN105362858A (en) | 2016-03-02 |
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| CN201510838985.XA Pending CN105362858A (en) | 2015-11-27 | 2015-11-27 | Pharmaceutical for treating chronic bronchitis |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007197423A (en) * | 2005-12-27 | 2007-08-09 | Daiichi Sankyo Healthcare Co Ltd | Pharmaceutical composition containing fudosteine and anticholinergic agent |
| CN103550597A (en) * | 2013-11-15 | 2014-02-05 | 王芬 | Traditional Chinese medicine honeyed bolus for treating chronic bronchitis and preparation method thereof |
-
2015
- 2015-11-27 CN CN201510838985.XA patent/CN105362858A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007197423A (en) * | 2005-12-27 | 2007-08-09 | Daiichi Sankyo Healthcare Co Ltd | Pharmaceutical composition containing fudosteine and anticholinergic agent |
| CN103550597A (en) * | 2013-11-15 | 2014-02-05 | 王芬 | Traditional Chinese medicine honeyed bolus for treating chronic bronchitis and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 姜忠喆等: "《教师医疗预防手册》", 30 April 2012, 安徽人民出版社 * |
| 温梦霞: "《传世奇效偏方》", 31 July 2015, 福建科学技术出版社 * |
| 董选等: "中药散剂治疗慢性支气管炎举验", 《黑龙江医药科学》 * |
| 谢东泽: "《超越：中药西用在治疗结缔组织病中的探索和实践》", 31 October 2012, 江苏科学技术出版社 * |
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Application publication date: 20160302 |