CN105362506A - Dill seed liver-clearing and vision-improving tablet and preparation method thereof - Google Patents
Dill seed liver-clearing and vision-improving tablet and preparation method thereof Download PDFInfo
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Abstract
Disclosed are a dill seed liver-clearing and vision-improving tablet and a preparation method thereof. The tablet is made from a herbal extract, a filler, a cracking agent, a binder, a lubricant, a flavoring agent and a glidant. The herbal extract comprises materials preferably in parts by weight: dill seeds 30-45 parts, Fructus Sophorae 15-25 parts, Stigma Croci 15-25 parts, Flos Persicae 7-14 parts, Flos Campsis 7-14 parts, Caulis Trachelospermi 7-14 parts, Rhopilema 3-6 parts, Calculus Bovis 3-6 parts, Concha Margaritifera and Radix Arnebiae 3-6 parts. The preparation method comprises main steps: (1), preparing a herb extract: a, pretreating raw materials; b, preparing a mixed extract; c, performing filtering, concentrating and drying; (2), preparing the dill seed liver-clearing and vision-improving tablet: a, performing mixing; b, performing dying; and performing mixing. The Dill seed liver-clearing and vision-improving tablet is effective in clearing liver and improving vision, astringing to stop bleeding and strengthening exterior and reducing sweat in long-term consumption.
Description
Technical field
The present invention relates to a kind of health product, particularly a kind of Fructus anethi liver heat removing and eyesight improving sheet and preparation method thereof.
Background technology
Liver has catharsis effect, likes happy and dislikes depressed.As the liver failing to maintain the normal flow of QI or be in a very depressed state is not relaxed, all depression of liver-QI can be caused.The common hypochondriac pain of clinical manifestation. uncomfortable in chest. gastral cavity is swollen. belch. the diseases such as menoxenia.
The liver failing to maintain the normal flow of QI, the syndrome that depression and stagnation of QI shows.Many because of depressed emotion, or the invasion of unexpected direct stimulation and other pathogenic factor and falling ill.The liver failing to maintain the normal flow of QI, mechanism of qi pent-up, then depressed emotion; Of a specified duration strongly fragrant puzzled, lose its submissive happy property, therefore being irritable and getting angry easily.Production of phlegm due to stagnation of QI, phlegm rising following QI, fights to tie and then sees globus hystericus in pharynx, and accumulating in neck is then goiter, qi disease involving blood, qi depression to blood stasis, disharmony of Chong and Conception Channels, therefore menoxenia or abdominal pain during menstruation.Gas gathers blood agglomeration, with the passing of time becomes Guo abdominal mass to gather.Control suitable dispersing the stagnated live-QI to relieve the stagnation of QI, be equipped with activating QI to eliminate phlegm if desired, the methods such as movable blood soft hard.
Liver controlling conveyance and dispersion, has the function of emotion regulation, syndrome of stagnation of liver qi, general depressed emotion, Liver Channel cross position feeling of distension and oppression pain occur, the breast side of body or few abdominal distention is vexed alters pain, uncomfortable in chest, sighing frequently, depressed emotion irritability, or foreign body in pharynx sense, or cervical region goiter, or the lower lump of the side of body.
At present, on market, the medicine of liver heat removing and eyesight improving or health product have a lot, but the effect of most drug is not fine, and the side effect of most drug is more, can damage health, though health product have certain effect, but its price is high, therefore, market is badly in need of a kind of pure natural, the Fructus anethi liver heat removing and eyesight improving sheet that has no side effect and preparation method thereof.
Summary of the invention
The object of this invention is to provide a kind of Fructus anethi liver heat removing and eyesight improving sheet and preparation method thereof, long-term taking has liver heat removing and eyesight improving, astringing to arrest bleeding; Effect of strengthening superficial resistance to stop perspiration.
Object of the present invention is achieved through the following technical solutions:
A kind of Fructus anethi liver heat removing and eyesight improving sheet, be made up of Chinese medicine extract, filler, disintegrating agent, binding agent, lubricant, correctives, fluidizer, by weight percentage, Chinese medicine extract 20-60%, filler 20-50%, disintegrating agent 10-40%, binding agent 1-20%, lubricant 1-5%, correctives 1-5%, fluidizer 1-5%; By weight, Chinese medicine extract 20-60 part, filler 20-50 part, disintegrating agent 10-40 part, binding agent 1-20 part, lubricant 1-5 part, correctives 1-5 part, fluidizer 1-5 part.
Described a kind of Fructus anethi liver heat removing and eyesight improving sheet, by optimum weight number, Chinese medicine extract 40 parts, filler 30 parts, disintegrating agent 15 parts, binding agent 5 parts, lubricant 4 parts, correctives 3 parts, fluidizer 3 parts.
The preferred weight number of described Chinese medicine extract Raw is: Fructus anethi 30-45 part, Fructus Sophorae 15-25 part, Stigma Croci 15-25 part, Flos persicae 7-14 part, Flos Campsis 7-14 part, Caulis Trachelospermi 7-14 part, Umbrella Rhopilema esculenta 3-6 part, Calculus Bovis 3-6 part, Concha Margaritifera 3-6 part, large Radix Arnebiae (Radix Lithospermi) 3-6 part.
The optimum weight number of described Chinese medicine extract Raw is: Fructus anethi 40 parts, the Fructus Sophorae 20 parts, Stigma Croci 18 parts, 14 parts, Flos persicae, Flos Campsis 10 parts, Caulis Trachelospermi 7 parts, Umbrella Rhopilema esculenta 6 parts, Calculus Bovis 5 parts, Concha Margaritifera 4 parts, large Radix Arnebiae (Radix Lithospermi) 3 parts.
Described filler is the mixing of one or more in microcrystalline Cellulose, starch, lactose, dextrin, sucrose; Described disintegrating agent is low-substituted hydroxypropyl cellulose; Described binding agent is starch slurry or polyvidone k30 or hypromellose; Described lubricant is one or both the mixing in magnesium stearate, sodium lauryl sulphate; Described correctives is the mixing of one or more in aspartame, steviosin, citric acid, essence; Described fluidizer is one or both the mixing in silicon dioxide, Pulvis Talci.
Described a kind of Fructus anethi liver heat removing and eyesight improving sheet and preparation method thereof, is characterized in that: the key step of its preparation method is:
(1) Chinese medicine extract is prepared:
A, pretreatment of raw material: by weight, choose Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi), clean and remove impurity, for subsequent use;
B, prepare mixed extract: by Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi) mix homogeneously, then use soak by water three times, first time adds the water of 14 times, moderate heat decocts 2-3 hour, filters, and extracts filtrate, second time adds the water of 12 times, and moderate heat decocts 1.5-2 hour, filters, extract filtrate, the water big fire adding 10 for the third time decocts 0.5 hour, filters, extract filtrate, merge three filtrates, obtain mixed extract, for subsequent use;
C, filtration, concentrated, dry: to get mixed extract, filter, then carry out concentrating under reduced pressure, when being concentrated into 60 DEG C, relative density is the clear paste of 1.22-1.3, is then placed in spray dryer and carries out spraying dry, drying is placed in pulverizer and pulverizes, and crosses 60 mesh sieves, obtains Chinese medicine extract;
(2) Fructus anethi liver heat removing and eyesight improving sheet is prepared:
A, mixing: by weight, get Chinese medicine extract, filler, disintegrating agent mix homogeneously, be then placed in wet granulator, binding agent is put into feed tank, open machine, adjustment parameter, opens simultaneously and shears fly cutter, 2-5 minute, discharging, use oscillating granulator, cross 16 order nylon screens and granulate, obtained wet granular;
B, drying: wet granular is placed in dehydrator and dries, after oven dry, adopt ultraviolet disinfection, obtain granulate;
C, mixing: by granulate, lubricant, correctives, fluidizer mixing, be placed in three-dimensional motion mixer mixing 15-25 minute, then use rotary tablet machine tabletting, obtained a kind of Fructus anethi liver heat removing and eyesight improving sheet.
In medicine: large Radix Arnebiae (Radix Lithospermi), removing heat from blood, invigorates blood circulation, heat clearing away, removing toxic substances; Control warm macule, jaundice due to damp-heat, purpura, tell, be defeated in battle, hematuria, stranguria with turbid discharge, constipation with heat retention, burn, eczema, erysipelas, carbuncle and ulcer; Shrubalthea Bark, blood circulation promoting regulates qi, dispelling, collateral-activating pain relieving; For stomachache, stomachache, dysmenorrhea, arthralgia, injury from falling down etc.; Herba cassiae occidentalis, liver heat removing and eyesight improving, stomach-invigorating intestine-moisturizing; For hypertension complicated headache, conjunctival congestion and swelling pain, oral erosion, habitual constipation, dysentery is suffered from abdominal pain, chronic enteritis; Flos Cannabis, dispels the wind; Invigorate blood circulation; Hair growth promoting, the sick numb limbs and tense tendons of main air; Pruritus all over; Women's amenorrhea, Caulis et folium stauntoniae, dispels the wind and network; Promoting blood circulation and stopping pain; Inducing diuresis to remove edema, main air pain of dampness syndrome; The pain of stomach, intestinal and biliary diseases; Trigeminal neuralgia; Traumatic injury; Dysmenorrhea; Dysuria; Edema, Flos Camelliae Japonicae, cooling blood for hemostasis; Dissipating blood stasis; Repercussive swells, main haematemesis; Epistaxis; Hemoptysis; Have blood in stool; Hemorrhoidal bleeding; Red dysentery; Stranguria with blood; Metrorrhagia; Leukorrhagia; Scald; Injury from falling down, Herba bromi japonici, astringing to arrest bleeding; Strengthening superficial resistance to stop perspiration, main haematemesis; Have blood in stool; Metrorrhagia; Spontaneous perspiration; Night sweat; Leucorrhea, Herba Violae, heat-clearing and toxic substances removing; Removing heat from blood is subsided a swelling, and is mainly used to furuncle swelling toxin; Carbuncle carbuncle on the back; Erysipelas; Venom, for furuncle swelling toxin, carbuncle carbuncle on the back, erysipelas, venom, Herba Dianthi, diuresis; Clearing away damp-heat; Promoting blood circulation to restore menstrual flow, main urinary obstruction; Pyretic stranguria; Stranguria with blood; Stranguria caused by urinary stone; Amenorrhea; Conjunctival congestion and swelling pain; Carbuncle sore tumefacting virus; Eczema pruritus, inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow, and for pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction, drenches the puckery pain of drop, menstruation apolipsis.
Beneficial effect of the present invention: a kind of Fructus anethi liver heat removing and eyesight improving sheet of the present invention, based on secret prescription handed down in the family from generation to generation, selected Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi), etc. raw material combine, the drug effect of various medicine is made to produce synergism, thus can be effective, long-term taking has liver heat removing and eyesight improving, clearing away heat and cooling blood; Effect of blood stasis-eliminating and stagnation-dissipating.
The present invention is through two groups of clinical verifications, and wherein one group is that treatment group takes the present invention, takes the present invention every day once, within 7 days, be a course for the treatment of, another group matched group takes liver heat removing and eyesight improving capsule, and every day uses once, it within 7 days, is a course for the treatment of, every group selection outpatient 52 example, wherein man 32 example, female 20 example, max age 75 years old, minimal ages 35 years old, clinical manifestation is cold type of pain in abdomen, feeling of fullness is eaten less, the dirty vomiting of acute diseases such as cholera and sunstroke, and table 1 is for taking the contrasting data after the course for the treatment of:
Table 1 is taken front and back and is compared (unit: people) two groups of courses for the treatment of
There were significant differences for treatment group and matched group, thus can find out that the present invention's application clinically has significant curative effect.
Technological advantage of the present invention is: 1, select raw material science, and production technology is advanced; 2, do not add spice and antiseptic in product, keep local flavor and the nutrition of raw material itself, be easily absorbed by the body; 3, raw material sources are extensive, add process line short, the easy processing and manufacturing of product.
Detailed description of the invention
Embodiment 1
A kind of Fructus anethi liver heat removing and eyesight improving sheet, be made up of Chinese medicine extract, filler, disintegrating agent, binding agent, lubricant, correctives, fluidizer, by weight percentage, Chinese medicine extract 20-60%, filler 20-50%, disintegrating agent 10-40%, binding agent 1-20%, lubricant 1-5%, correctives 1-5%, fluidizer 1-5%; By weight, Chinese medicine extract 20-60 part, filler 20-50 part, disintegrating agent 10-40 part, binding agent 1-20 part, lubricant 1-5 part, correctives 1-5 part, fluidizer 1-5 part.
Described a kind of Fructus anethi liver heat removing and eyesight improving sheet, by optimum weight number, Chinese medicine extract 40 parts, filler 30 parts, disintegrating agent 15 parts, binding agent 5 parts, lubricant 4 parts, correctives 3 parts, fluidizer 3 parts.
The preferred weight number of described Chinese medicine extract Raw is: Fructus anethi 30-45 part, Fructus Sophorae 15-25 part, Stigma Croci 15-25 part, Flos persicae 7-14 part, Flos Campsis 7-14 part, Caulis Trachelospermi 7-14 part, Umbrella Rhopilema esculenta 3-6 part, Calculus Bovis 3-6 part, Concha Margaritifera 3-6 part, large Radix Arnebiae (Radix Lithospermi) 3-6 part.
The optimum weight number of described Chinese medicine extract Raw is: Fructus anethi 40 parts, the Fructus Sophorae 20 parts, Stigma Croci 18 parts, 14 parts, Flos persicae, Flos Campsis 10 parts, Caulis Trachelospermi 7 parts, Umbrella Rhopilema esculenta 6 parts, Calculus Bovis 5 parts, Concha Margaritifera 4 parts, large Radix Arnebiae (Radix Lithospermi) 3 parts.
Described filler is the mixing of one or more in microcrystalline Cellulose, starch, lactose, dextrin, sucrose; Described disintegrating agent is low-substituted hydroxypropyl cellulose; Described binding agent is starch slurry or polyvidone k30 or hypromellose; Described lubricant is one or both the mixing in magnesium stearate, sodium lauryl sulphate; Described correctives is the mixing of one or more in aspartame, steviosin, citric acid, essence; Described fluidizer is one or both the mixing in silicon dioxide, Pulvis Talci.
Described a kind of Fructus anethi liver heat removing and eyesight improving sheet and preparation method thereof, the key step of its preparation method is:
(1) Chinese medicine extract is prepared:
A, pretreatment of raw material: by weight, choose Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi), clean and remove impurity, for subsequent use;
B, prepare mixed extract: by Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi) mix homogeneously, then use soak by water three times, first time adds the water of 14 times, moderate heat decocts 2-3 hour, filters, and extracts filtrate, second time adds the water of 12 times, and moderate heat decocts 1.5-2 hour, filters, extract filtrate, the water big fire adding 10 for the third time decocts 0.5 hour, filters, extract filtrate, merge three filtrates, obtain mixed extract, for subsequent use;
C, filtration, concentrated, dry: to get mixed extract, filter, then carry out concentrating under reduced pressure, when being concentrated into 60 DEG C, relative density is the clear paste of 1.22-1.3, is then placed in spray dryer and carries out spraying dry, drying is placed in pulverizer and pulverizes, and crosses 60 mesh sieves, obtains Chinese medicine extract;
(2) Fructus anethi liver heat removing and eyesight improving sheet is prepared:
A, mixing: by weight, get Chinese medicine extract, filler, disintegrating agent mix homogeneously, be then placed in wet granulator, binding agent is put into feed tank, open machine, adjustment parameter, opens simultaneously and shears fly cutter, 2-5 minute, discharging, use oscillating granulator, cross 16 order nylon screens and granulate, obtained wet granular;
B, drying: wet granular is placed in dehydrator and dries, after oven dry, adopt ultraviolet disinfection, obtain granulate;
C, mixing: by granulate, lubricant, correctives, fluidizer mixing, be placed in three-dimensional motion mixer mixing 15-25 minute, then use rotary tablet machine tabletting, obtained a kind of Fructus anethi liver heat removing and eyesight improving sheet.
Claims (6)
1. a Fructus anethi liver heat removing and eyesight improving sheet, it is characterized in that: be made up of Chinese medicine extract, filler, disintegrating agent, binding agent, lubricant, correctives, fluidizer, by weight percentage, Chinese medicine extract 20-60%, filler 20-50%, disintegrating agent 10-40%, binding agent 1-20%, lubricant 1-5%, correctives 1-5%, fluidizer 1-5%; By weight, Chinese medicine extract 20-60 part, filler 20-50 part, disintegrating agent 10-40 part, binding agent 1-20 part, lubricant 1-5 part, correctives 1-5 part, fluidizer 1-5 part.
2. a kind of Fructus anethi liver heat removing and eyesight improving sheet according to claim 1, is characterized in that: by optimum weight number, Chinese medicine extract 40 parts, filler 30 parts, disintegrating agent 15 parts, binding agent 5 parts, lubricant 4 parts, correctives 3 parts, fluidizer 3 parts.
3. a kind of Fructus anethi liver heat removing and eyesight improving sheet according to claim 1, is characterized in that: the preferred weight number of described Chinese medicine extract Raw is: Fructus anethi 30-45 part, Fructus Sophorae 15-25 part, Stigma Croci 15-25 part, Flos persicae 7-14 part, Flos Campsis 7-14 part, Caulis Trachelospermi 7-14 part, Umbrella Rhopilema esculenta 3-6 part, Calculus Bovis 3-6 part, Concha Margaritifera 3-6 part, large Radix Arnebiae (Radix Lithospermi) 3-6 part.
4. a kind of Fructus anethi liver heat removing and eyesight improving sheet according to claim 1, is characterized in that: the optimum weight number of described Chinese medicine extract Raw is: Fructus anethi 40 parts, the Fructus Sophorae 20 parts, Stigma Croci 18 parts, 14 parts, Flos persicae, Flos Campsis 10 parts, Caulis Trachelospermi 7 parts, Umbrella Rhopilema esculenta 6 parts, Calculus Bovis 5 parts, Concha Margaritifera 4 parts, large Radix Arnebiae (Radix Lithospermi) 3 parts.
5. a kind of Fructus anethi liver heat removing and eyesight improving sheet according to claim 1, is characterized in that: described filler is the mixing of one or more in microcrystalline Cellulose, starch, lactose, dextrin, sucrose; Described disintegrating agent is low-substituted hydroxypropyl cellulose; Described binding agent is starch slurry or polyvidone k30 or hypromellose; Described lubricant is one or both the mixing in magnesium stearate, sodium lauryl sulphate; Described correctives is the mixing of one or more in aspartame, steviosin, citric acid, essence; Described fluidizer is one or both the mixing in silicon dioxide, Pulvis Talci.
6. a kind of Fructus anethi liver heat removing and eyesight improving sheet according to claim 1-5 and preparation method thereof, is characterized in that: the key step of its preparation method is:
(1) Chinese medicine extract is prepared:
A, pretreatment of raw material: by weight, choose Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi), clean and remove impurity, for subsequent use;
B, prepare mixed extract: by Fructus anethi, the Fructus Sophorae, Stigma Croci, Flos persicae, Flos Campsis, Caulis Trachelospermi, Umbrella Rhopilema esculenta, Calculus Bovis, Concha Margaritifera, large Radix Arnebiae (Radix Lithospermi) mix homogeneously, then use soak by water three times, first time adds the water of 14 times, moderate heat decocts 2-3 hour, filters, and extracts filtrate, second time adds the water of 12 times, and moderate heat decocts 1.5-2 hour, filters, extract filtrate, the water big fire adding 10 for the third time decocts 0.5 hour, filters, extract filtrate, merge three filtrates, obtain mixed extract, for subsequent use;
C, filtration, concentrated, dry: to get mixed extract, filter, then carry out concentrating under reduced pressure, when being concentrated into 60 DEG C, relative density is the clear paste of 1.22-1.3, is then placed in spray dryer and carries out spraying dry, drying is placed in pulverizer and pulverizes, and crosses 60 mesh sieves, obtains Chinese medicine extract;
(2) Fructus anethi liver heat removing and eyesight improving sheet is prepared:
A, mixing: by weight, get Chinese medicine extract, filler, disintegrating agent mix homogeneously, be then placed in wet granulator, binding agent is put into feed tank, open machine, adjustment parameter, opens simultaneously and shears fly cutter, 2-5 minute, discharging, use oscillating granulator, cross 16 order nylon screens and granulate, obtained wet granular;
B, drying: wet granular is placed in dehydrator and dries, after oven dry, adopt ultraviolet disinfection, obtain granulate;
C, mixing: by granulate, lubricant, correctives, fluidizer mixing, be placed in three-dimensional motion mixer mixing 15-25 minute, then use rotary tablet machine tabletting, obtained a kind of Fructus anethi liver heat removing and eyesight improving sheet.
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| CN201510839061.1A CN105362506A (en) | 2015-11-27 | 2015-11-27 | Dill seed liver-clearing and vision-improving tablet and preparation method thereof |
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| CN201510839061.1A CN105362506A (en) | 2015-11-27 | 2015-11-27 | Dill seed liver-clearing and vision-improving tablet and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185733A (en) * | 2007-08-02 | 2008-05-28 | 江中药业股份有限公司 | Jianweixiaoshi orally disintegrating tablets and preparation method |
| CN102920893A (en) * | 2012-12-04 | 2013-02-13 | 青海普兰特药业有限公司 | Fifteen-component alplily eyesight improving tablet and preparation process thereof |
| CN104940448A (en) * | 2014-03-27 | 2015-09-30 | 哈尔滨浩拓生物科技开发有限公司 | Pleurotus sajor-caju dissolved granules capable of clearing away heart-fire for improving eyesight and production method thereof |
-
2015
- 2015-11-27 CN CN201510839061.1A patent/CN105362506A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101185733A (en) * | 2007-08-02 | 2008-05-28 | 江中药业股份有限公司 | Jianweixiaoshi orally disintegrating tablets and preparation method |
| CN102920893A (en) * | 2012-12-04 | 2013-02-13 | 青海普兰特药业有限公司 | Fifteen-component alplily eyesight improving tablet and preparation process thereof |
| CN104940448A (en) * | 2014-03-27 | 2015-09-30 | 哈尔滨浩拓生物科技开发有限公司 | Pleurotus sajor-caju dissolved granules capable of clearing away heart-fire for improving eyesight and production method thereof |
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Application publication date: 20160302 |