Full-automatic liquid phase chromatographic column loading machine
Technical field
The present invention relates to a kind of full-automatic liquid phase chromatographic column loading machine, belong to liquid-phase chromatographic column technical field.
Background technology
At present, the dress column method of liquid-phase chromatographic column is all that dress post is due to work by hand using dress post or semi-automatic dress post by hand
Sequence is relatively more, and manpower is wasted than more serious, and production efficiency is relatively low;And the semi-automatic packing column machine of prior art, also it is not carried out complete
Automatic mode, its production efficiency is not also high.
The content of the invention
The technical problems to be solved by the invention are that the defect for overcoming prior art is filled there is provided a kind of full-automatic liquid chromatogram
Post machine, it can realize the automatic Loading to liquid-phase chromatographic column, so as to improve production efficiency and save human cost.
In order to solve the above-mentioned technical problem, the technical scheme is that:A kind of full-automatic liquid phase chromatographic column loading machine, it is wrapped
Include:
Work disk component, and the work disk component, which has, can drive the scratch diskette component of rotation, and the scratch diskette component exists
It is disposed with using the center of scratch diskette component as the circumference in the center of circle and along the direction of rotation of scratch diskette component into post station, pressure
Bottom plug station, charging station, pressure top plug station and finished product placing station;
Enter post disk component, it is described enter post disk component be arranged on the periphery for entering post station of scratch diskette component, it is described enter post disk
Column jecket is delivered on post station by part;
Bottom plug part is pressed, the pressure bottom plug part is arranged on the periphery of the pressure bottom plug station of scratch diskette component, the pressure bottom
Bottom plug is pressed into the column jecket on bottom plug station by plunger member, makes the column jecket formation first that bottom plug has been gone up on pressure bottom plug station
Semi-finished product;
Feed part, and the charging part is arranged on the periphery of the charging station of scratch diskette component, and the charging part will
Filter material injects the filter material intracavitary of the first semi-finished product, makes to have been injected into the first semi-finished product formation the of filter material on charging station
Two semi-finished product;
Plunger member is arranged in the periphery of the pressure top plug station of scratch diskette component, the pressure in plunger member in pressure, the pressure
Top plug is pressed into the second semi-finished product by plunger member, make top plug on pressure top plug station the second semi-finished product formed just into
Product;
Finished product goes out disk component, and the finished product goes out the periphery that disk component is arranged on the finished product placing station of scratch diskette component, institute
State finished product and go out disk component and the liquid-phase chromatographic column being finally completed is transferred out into scratch diskette component.
Further for effective progress of the work on subsequent work stations, full-automatic liquid phase chromatographic column loading machine also includes compression leg portion
Part, the scratch diskette component is entering to be additionally provided with compression leg station between post station and pressure bottom plug station, and the compression leg part is set
In the periphery of the compression leg station of scratch diskette component, the compression leg part pressurizes to column jecket, column jecket is returned on compression leg station
Position.
Further for by the Torque Control of tamponade in column jecket, in rational scope, full-automatic liquid phase chromatographic column loading machine is also
Including tamponade Torque Control part, the scratch diskette component is additionally provided with tamponade between pressure top plug station and finished product placing station
Torque Control station, the tamponade Torque Control part is arranged on the periphery of the tamponade Torque Control station of scratch diskette component.
Further provide it is a kind of enter post disk component concrete structure, it is described enter post disk component include peripheral positioning disk component
With can drive rotation enter post disk component, enter post disk component it is cylindrical on be provided with the column jecket groove of accommodating column jecket, peripheral positioning disk
Component is arranged on into the periphery of post disk component, and one of column jecket groove and scratch diskette component to enter post station corresponding, when
When entering the rotation of post disk component, it is described enter post disk component enter post by what the column jecket being contained on column jecket groove was sequentially sent to scratch diskette component
Station.
Further provide a kind of concrete structure for pressing bottom plug part and/or the upper plunger member of pressure, the pressure bottom plug part and/
Or the upper plunger member of pressure includes tamponade centering body, seben supporting plate, seben hopper, seben vibrating transportation guide rail and seben press-in group
Part, one end of seben vibrating transportation guide rail is connected with seben hopper, and the other end and the seben supporting plate of seben vibrating transportation guide rail connect
Connect, tamponade centering body includes centering cylinder and centering Anchor plate kit, centering Anchor plate kit is arranged on the movable end of centering cylinder
On, the seben supporting plate is arranged on centering Anchor plate kit, and the seben press-in component includes press-in cylinder and press-in post, press-in
Post is connected on the movable end of press-in cylinder, and press-in post is engaged with seben supporting plate, and when being pressed into cylinder action, press-in post will be filled in
Seben press-in column jecket on plate support plate.
A kind of concrete structure for the part that feeds is further provided, the charging part includes conveying screw rod, loading hopper group
Part and driving transmission component, the bottom of the loading hopper component is provided with exit portion, and the bottom of exit portion is provided with
Discharging opening, the exit portion of the loading hopper component is arranged on the periphery of conveying screw rod, the driving transmission component and conveying spiral shell
Bar is connected.
A kind of concrete structure of loading hopper component is further provided, the loading hopper component from top to bottom includes adding successively
Hopper, material storage tube and inferior pyramidal hopper, and the bottom of inferior pyramidal hopper is exit portion.
Further, the driving transmission component includes servomotor and central shaft, one end of central shaft and servomotor
Output shaft is connected, and the other end and the conveying screw rod of central shaft are connected.
Further provide the concrete structure that a kind of finished product goes out disk component, the finished product go out disk component including pusher cylinder and
Pusher bracket component, pusher bracket component is arranged on the movable end of pusher cylinder, when pusher cylinder is acted, the pusher branch
Liquid-phase chromatographic column on finished product placing station is released scratch diskette component by frame component.
Employ after above-mentioned technical proposal, scratch diskette component is by the column jecket being placed on scratch diskette component successively in each work
Rotate, column jecket can be delivered to first on post station by entering post disk component on position, then scratch diskette component rotates, and will enter post
Column jecket on station is rotated to compression leg station, and the column jecket on compression leg station is forced into rational position by compression leg part,
Then scratch diskette component is rotated again, and the column jecket on compression leg station is rotated to pressure bottom plug station, by pressing bottom plug part the bottom of by
Plug is pressed into the column jecket on bottom plug station, makes column jecket the first semi-finished product of formation that bottom plug has been gone up on pressure bottom plug station, so
Scratch diskette component is rotated again afterwards, and the first semi-finished product on bottom plug station will be pressed to rotate to charging station, and by feeding, part will
Filter material injection charging station on the first semi-finished product in, then scratch diskette component rotates again, will feed station on first
Semi-finished product are rotated to pressure top plug station, and top plug is pressed into the second semi-finished product by pressure upper plunger member, made on pressure top plug station
The second semi-finished product through upper complete top plug form just finished product;Then scratch diskette component rotates again, by press top plug station on it is first into
Product are rotated to tamponade Torque Control station, and tamponade Torque Control process is carried out to column jecket by tamponade Torque Control part;Then
Scratch diskette component is rotated again, and the liquid-phase chromatographic column on tamponade Torque Control station is rotated to finished product placing station, then passes through
Finished product goes out disk component and the liquid-phase chromatographic column on finished product placing station is transferred out into scratch diskette component, and this makes it possible to realize pair
The automatic Loading of liquid-phase chromatographic column, so as to improve production efficiency and save human cost.
Brief description of the drawings
Fig. 1 is the structural representation of the full-automatic liquid phase chromatographic column loading machine of the present invention;
Fig. 2 is Fig. 1 top view;
Fig. 3 is Fig. 1 right view;
Fig. 4 is the structural representation for pressing bottom plug part or the upper plunger member of pressure of the invention;
Fig. 5 is the structural representation of the charging part of the present invention.
Embodiment
In order that present disclosure is easier to be clearly understood, it is right below according to specific embodiment and with reference to accompanying drawing
The present invention is described in further detail.
As shown in Fig. 1~5, a kind of full-automatic liquid phase chromatographic column loading machine, it includes:
Work disk component, and the work disk component, which has, can drive the scratch diskette component 1 of rotation, the scratch diskette component 1
It is disposed with using the center of scratch diskette component 1 as the circumference in the center of circle and along the direction of rotation of scratch diskette component 1 into post work
Position, pressure bottom plug station, charging station, pressure top plug station and finished product placing station;
Enter post disk component 2, it is described enter post disk component 2 be arranged on the periphery for entering post station of scratch diskette component 1, it is described enter post
Column jecket is delivered on post station by disk component 2;
Bottom plug part 3 is pressed, the pressure bottom plug part 3 is arranged on the periphery of the pressure bottom plug station of scratch diskette component 1, the pressure
Bottom plug is pressed into the column jecket on bottom plug station by bottom plug part 3, forms the column jecket that bottom plug has been gone up on pressure bottom plug station
First semi-finished product;
Feed part 4, and the charging part 4 is arranged on the periphery of the charging station of scratch diskette component 1, the charging part
4 inject filter material the filter material intracavitary of the first semi-finished product, make the first semi-finished product shape that filter material is had been injected on charging station
Into the second semi-finished product;
Plunger member 5 is arranged on the periphery of the pressure top plug station of scratch diskette component 1, the pressure in plunger member 5 in pressure, the pressure
Top plug is pressed into the second semi-finished product by upper plunger member 5, the second semi-finished product of top plug on pressure top plug station is formed just
Finished product;
Finished product goes out disk component 6, and the finished product goes out the periphery that disk component 6 is arranged on the finished product placing station of scratch diskette component 1,
The finished product goes out disk component 6 and the liquid-phase chromatographic column being finally completed is transferred out into scratch diskette component 1.
As shown in Fig. 2 full-automatic liquid phase chromatographic column loading machine also includes compression leg part 7, the scratch diskette component 1 is entering post work
Compression leg station is additionally provided between position and pressure bottom plug station, the compression leg part 7 is arranged on the compression leg station of scratch diskette component
Periphery, the compression leg part 7 pressurizes to column jecket, column jecket is playbacked on compression leg station.
As shown in Fig. 2 full-automatic liquid phase chromatographic column loading machine also includes tamponade Torque Control part 8, the scratch diskette component 1
Tamponade Torque Control station, the tamponade Torque Control part 8 are additionally provided between pressure top plug station and finished product placing station
It is arranged on the periphery of the tamponade Torque Control station of scratch diskette component 1.
As shown in Fig. 2 it is described enter post disk component 2 include peripheral positioning disk component 21 and can drive rotation enter post disk component
22, enter post disk component 22 it is cylindrical on be provided with the column jecket groove of accommodating column jecket, peripheral positioning disk component 21 is arranged on into post disk group
The periphery of part 22, and one of column jecket groove and scratch diskette component 1 to enter post station corresponding, rotated when entering post disk component 22
When, it is described enter post disk component 22 enter post station by what the column jecket being contained on column jecket groove was sequentially sent to scratch diskette component 1.
As shown in figure 4, the pressure bottom plug part 3 and/or the upper plunger member 5 of pressure include tamponade centering body, seben supporting plate 31,
Seben hopper 32, seben vibrating transportation guide rail 33 and seben press-in component, one end and the seben material of seben vibrating transportation guide rail 33
Bucket 32 is connected, and the other end of seben vibrating transportation guide rail 33 is connected with seben supporting plate 31, and tamponade centering body includes centering cylinder
34 and centering Anchor plate kit 35, centering Anchor plate kit 35 is arranged on the movable end of centering cylinder 34, and the seben supporting plate 31 is pacified
On centering Anchor plate kit 35, the seben press-in component includes press-in cylinder 36 and press-in post 37, and press-in post 37 is connected to
On the movable end for being pressed into cylinder 36, press-in post 37 is engaged with seben supporting plate 31, and when being pressed into the action of cylinder 36, press-in post 37 will
Seben press-in column jecket on seben supporting plate 31.
As shown in figure 5, the charging part 4 includes conveying screw rod 41, loading hopper component and driving transmission component, it is described to add
The bottom of hopper component is provided with exit portion, and the bottom of exit portion is provided with discharging opening, the loading hopper component
Exit portion is arranged on the periphery of conveying screw rod 41, and the driving transmission component is connected with conveying screw rod 41.
As shown in figure 5, the loading hopper component from top to bottom includes loading hopper 42, material storage tube 43 and inferior pyramidal hopper successively
44, and the bottom of inferior pyramidal hopper 44 is exit portion.
As shown in figure 5, the driving transmission component includes servomotor 45 and central shaft 46, one end of central shaft 46 is with watching
The output shaft drive connection of motor 45 is taken, the other end and the conveying screw rod 41 of central shaft 46 are connected.
As shown in Fig. 2 the finished product, which goes out disk component 6, includes pusher cylinder 61 and pusher bracket component 62, pusher support group
Part 62 is arranged on the movable end of pusher cylinder 61, and when pusher cylinder 61 is acted, the pusher bracket component 62 goes out finished product
Liquid-phase chromatographic column on disk station releases scratch diskette component 1.
The operation principle of the present invention is as follows:
Scratch diskette component 1 rotates the column jecket being placed on scratch diskette component 1 on each station successively, can pass through first
Enter post disk component 2 column jecket is delivered on post station, then scratch diskette component 1 rotates, the column jecket entered on post station is rotated
To compression leg station, the column jecket on compression leg station is forced into by rational position by compression leg part 7, then scratch diskette component 1
Rotate again, the column jecket on compression leg station is rotated to pressure bottom plug station, bottom plug work is pressed into by pressing bottom plug part 3 by bottom plug
In column jecket on position, make to have gone up column jecket the first semi-finished product of formation of bottom plug on pressure bottom plug station, then scratch diskette component 1 is again
Secondary rotation, will press the first semi-finished product on bottom plug station to rotate to charging station, injects filter material by the part 4 that feeds and feed
In the first semi-finished product on station, then scratch diskette component 1 is rotated again, and the first semi-finished product fed on station are rotated to pressure
Top plug, is pressed into the second semi-finished product by top plug station by the upper plunger member 5 of pressure, makes the of top plug on pressure top plug station
Two semi-finished product form just finished product;Then scratch diskette component 1 is rotated again, and the first finished product on top plug station will be pressed to rotate to tamponade power
Square controls station, and tamponade Torque Control process is carried out to column jecket by tamponade Torque Control part 8;Then scratch diskette component 1 is again
Secondary rotation, the liquid-phase chromatographic column on tamponade Torque Control station is rotated to finished product placing station, then go out disk component by finished product
Liquid-phase chromatographic column on finished product placing station is transferred out into scratch diskette component 1, this makes it possible to realize to liquid-phase chromatographic column
Automatic Loading so that improve production efficiency and save human cost.
Particular embodiments described above, pair present invention solves the technical problem that, technical scheme and beneficial effect carry out
It is further described, should be understood that the specific embodiment that the foregoing is only the present invention, is not limited to this
Invention, within the spirit and principles of the invention, any modification, equivalent substitution and improvements done etc. should be included in this hair
Within bright protection domain.