CN105343758A - 用于治疗由脾胃不和引起的小儿厌食症的药物 - Google Patents

用于治疗由脾胃不和引起的小儿厌食症的药物 Download PDF

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CN105343758A
CN105343758A CN201510990622.8A CN201510990622A CN105343758A CN 105343758 A CN105343758 A CN 105343758A CN 201510990622 A CN201510990622 A CN 201510990622A CN 105343758 A CN105343758 A CN 105343758A
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林书凤
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Abstract

本发明公开了一种用于治疗由脾胃不和引起的小儿厌食症的药物，主要由下述重量份配比的原料制成：茯苓8-12份，藿香8-12份，木香2-4份，川朴2-4份，胡黄连2-4份，砂仁2-4份，焦神曲8-12份，鸡内金2-4份，栀子4-8份，焦山楂8-12份，焦麦芽8-12份。本发明用于治疗由脾胃不和引起的小儿厌食症的药物，选取11种天然中药科学配伍，配方简单，各原料药协同作用起到清热化滞，理脾助运的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。有效率达到96.5％以上。

Description

用于治疗由脾胃不和引起的小儿厌食症的药物
技术领域
本发明涉及中药，具体是一种用于治疗由脾胃不和引起的小儿厌食症的药物。
背景技术
小儿厌食症是指小儿(主要是3～6岁)较长期食欲减退或食欲缺乏为主的症状。它是一种症状，并非一种独立的疾病。小儿厌食症又称消化功能紊乱。小儿厌食症在小儿时期很常见，主要的症状有呕吐，食欲不振、腹泻，便秘，腹胀，腹痛和便血等。正常儿童每隔3～4h胃内容物排空，血糖下降，就会产生食欲，喂养不当或饮食习惯不良，如吃饭不定时，饭前吃零食或糖果，胃内总有东西，血糖不下降，就不会有食欲。
本病长期得不到缓解，可并发疾病小儿营养不良，甚至引起发育障碍等，小儿处于不断生长发育中，相对比成人需要更多的各种营养素供给，如果各种营养素供给不足，不但会影响小儿的正常生长发育，严重时使生长发育停滞，体内脏器萎缩，这样必然会影响小儿的正常免疫系统，如由于厌食导致的严重的蛋白质--热能不足营养不良患儿，可出现细胞免疫功能紊乱和血清抗体减少，因而容易发生各种细菌，病毒和真菌等感染，且感染往往持续，迁延不愈，甚至危及生命，表现为反复感冒，发烧，或反复咳嗽，不吃，不好动，体重不增，个儿不长。
现在多以西药治疗为主，但是效果较慢，其副作用大，会引起其他疾病。而目前的一些中药的治疗效率也不甚理想，且疗效不显著。
发明内容
本发明的目的是提供一种疗效好、疗程短、成本低、无毒副作用的用于治疗由脾胃不和引起的小儿厌食症的药物。
实现本发明目的的技术方案是：
一种用于治疗由脾胃不和引起的小儿厌食症的药物，主要由下述重量份配比的原料制成：
茯苓8-12份，藿香8-12份，木香2-4份，川朴2-4份，胡黄连2-4份，砂仁2-4份，焦神曲8-12份，鸡内金2-4份，栀子4-8份，焦山楂8-12份，焦麦芽8-12份。
上述用于治疗由脾胃不和引起的小儿厌食症的药物，各原料的最佳重量份配比为：
茯苓10份，藿香10份，木香3份，川朴3份，胡黄连3份，砂仁3份，焦神曲10份，鸡内金3份，栀子6份，焦山楂10份，焦麦芽10份。
所述的原料药材在中药店及市场有售。
本发明药物的制备方法如下：按重量配比称取各原料药，加入混合置于容器中，再加原料量重量10-20倍的水煎煮3次，每次煎煮35-45min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.20-1.30的浸膏，加入辅料，制成相应的剂型，即得。
本发明中，各原料药的药理、功效如下：
茯苓：性味甘淡平，入心、肺、脾经。具有渗湿利水，健脾和胃，宁心安神的功效。可治小便不利，水肿胀满，痰饮咳逆，呕逆，恶阻，泄泻，遗精，淋浊，惊悸，健忘等症。
藿香：化湿醒脾，辟秽和中，解暑，发表。用于湿阻脾胃、脘腹胀满、湿温初起、呕吐、泄泻、暑湿、发热恶寒、恶寒发热、胸脘满闷等症。
木香：行气，止痛，健脾，消食。主治：行气止痛；调中导滞。主胞胁胀满足；脘腹胀痛；嗳吐泄泻；痢疾后重。用于胸脘胀痛、泻痢后重、食积不消、不思饮食；中气不省；突发耳聋；蛇虫咬伤；牙痛。
川朴：行气消积；燥湿除满；降逆平喘。主治：食积气滞；腹胀便秘；湿阻中焦，脘痞吐泻；痰壅气逆；胸满喘咳。
胡黄连：清热，凉血，燥湿。治疳疾，惊痫，泻痢，劳热骨蒸，自汗，盗汗，吐血，衄血，火眼，痔瘘，疮疡。
砂仁：有化湿开胃，温脾止泻，理气安胎的功效。用于湿浊中阻，脘痞不饥，脾胃虚寒，呕吐泄泻，妊娠恶阻，胎动不安。
焦神曲：为全麦粉和其他药物(青蒿、苍耳，辣蓼、杏仁、赤小豆等芽)混合后经发酵而成的加工品。具有消食化积、健脾和胃的功效。主要用于饮食停滞，消化不良，脘腹胀满，食欲不振，呕吐泻痢，以及妇人产后淤血腹痛，小儿腹大坚积等病证。
鸡内金：消积滞，健脾胃。治食积胀满，呕吐反胃，泻痢，疳积，消渴，遗溺，喉痹乳蛾，牙疳口疮。
栀子：泻火除烦，清热利湿，凉血解毒；外用消肿止痛。用于热病心烦，湿热黄疸，淋证涩痛，血热吐衄，目赤肿痛，火毒疮疡，外治扭挫伤痛。
焦山楂：有消食健胃、活血化瘀、收敛止痢之功能。对肉积痰饮、痞满吞酸、泻痢肠风、腰痛疝气、产后儿枕痛、恶露不尽、小儿乳食停滞等，均有疗效。
焦麦芽：用于脾虚食少，消化不良，乳房胀满，乳汁郁积。
本发明用于治疗由脾胃不和引起的小儿厌食症的药物，选取11种天然中药科学配伍，配方简单，各原料药协同作用起到清热化滞，理脾助运的效果，见效快，标本兼治，无毒副作用，而且其制备方法简单、服用方便，成本低。
具体实施方式
下面结合实施例对本发明内容作进一步的说明，但不是对本发明的限定。
实施例1
一种用于治疗由脾胃不和引起的小儿厌食症的药物，主要由下述重量份配比的原料制成：
茯苓8kg，藿香8kg，木香2kg，川朴2kg，胡黄连2kg，砂仁2kg，焦神曲8kg，鸡内金2kg，栀子4kg，焦山楂8kg，焦麦芽8kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量10倍的水煎煮3次，每次煎煮35min，合并煎煮液，过滤去渣，滤液浓缩至50℃下相对密度为1.20的浸膏，加入辅料，制成片剂，每片0.1g。
实施例2
一种用于治疗由脾胃不和引起的小儿厌食症的药物，主要由下述重量份配比的原料制成：
茯苓10kg，藿香10kg，木香3kg，川朴3kg，胡黄连3kg，砂仁3kg，焦神曲10kg，鸡内金3kg，栀子6kg，焦山楂10kg，焦麦芽10kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量15倍的水煎煮3次，每次煎煮38min，合并煎煮液，过滤去渣，滤液浓缩至54℃下相对密度为1.30的浸膏，加入辅料，制成片剂，每片0.2g。
实施例3
一种用于治疗由脾胃不和引起的小儿厌食症的药物，主要由下述重量份配比的原料制成：
茯苓12kg，藿香12kg，木香4kg，川朴4kg，胡黄连4kg，砂仁4kg，焦神曲12kg，鸡内金4kg，栀子8kg，焦山楂12kg，焦麦芽12kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量18倍的水煎煮3次，每次煎煮42min，合并煎煮液，过滤去渣，滤液浓缩至56℃下相对密度为1.20的浸膏，加入辅料，制成丸剂，每粒0.4g。
实施例4
一种用于治疗由脾胃不和引起的小儿厌食症的药物，主要由下述重量份配比的原料制成：
茯苓12kg，藿香12kg，木香4kg，川朴4kg，胡黄连4kg，砂仁4kg，焦神曲12kg，鸡内金4kg，栀子8kg，焦山楂12kg，焦麦芽12kg。
制备方法如下：按上述称取各原料药混合置于容器中，再加原料量重量20倍的水煎煮3次，每次煎煮45min，合并煎煮液，过滤去渣，滤液浓缩至60℃下相对密度为1.30的浸膏，加入辅料，制成丸剂，每粒0.5g。
为了进一步证明本发明中药的临床疗效，选择收治患者中的200例，对本发明药物的疗效进行临床观察。年龄2-6岁，随机分为4组，每组为50例，分别为实验组1-4组。
实验组1-4组分别服用实施例1-4的药物，每日3次，每次内服3片/粒，3天为一个疗程，连续服用2个疗程。其中显效190例，有效193例，治愈188例，无效7例，治愈率94％，有效率96.5％。

Claims (3)

1.一种用于治疗由脾胃不和引起的小儿厌食症的药物，其特征是：主要由下述重量份配比的原料制成：
茯苓8-12份，藿香8-12份，木香2-4份，川朴2-4份，胡黄连2-4份，砂仁2-4份，焦神曲8-12份，鸡内金2-4份，栀子4-8份，焦山楂8-12份，焦麦芽8-12份。
2.根据权利要求1所述的用于治疗由脾胃不和引起的小儿厌食症的药物，其特征是：各原料的最佳重量份配比为：
茯苓10份，藿香10份，木香3份，川朴3份，胡黄连3份，砂仁3份，焦神曲10份，鸡内金3份，栀子6份，焦山楂10份，焦麦芽10份。
3.根据权利要求1所述的用于治疗由脾胃引起的小儿厌食症的药物，其特征是：
制备方法如下：按重量配比称取各原料药，加入混合置于容器中，再加原料量重量10-20倍的水煎煮3次，每次煎煮35-45min，合并煎煮液，过滤去渣，滤液浓缩至50-60℃下相对密度为1.20-1.30的浸膏，加入辅料，制成相应的剂型，即得。
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