CN105343716A - 足癣治疗药物 - Google Patents

足癣治疗药物 Download PDF

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CN105343716A
CN105343716A CN201510846792.9A CN201510846792A CN105343716A CN 105343716 A CN105343716 A CN 105343716A CN 201510846792 A CN201510846792 A CN 201510846792A CN 105343716 A CN105343716 A CN 105343716A
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tinea pedis
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treating tinea
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532—Agastache, e.g. giant hyssop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

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Abstract

本发明涉及一种足癣治疗药物，是由下列质量比例的原料组成：藿香20-40份、地骨皮10-20份、鸦胆子20-30份、百部20-40份、明矾10-20份、大枫子20-40份、苦参10-30份、黄柏20-30份、蛇床子15-30份、大黄10-20份。本发明对足癣具有较好的治疗作用，且无明显毒副作用。

Description

足癣治疗药物
技术领域
本发明属于生物医药领域，具体涉及一种足癣治疗药物。
背景技术
足癣是由致病性真菌引起的足部皮肤病，具有传染性。足癣在全世界广为流行，在热带和亚热带地区更为普遍。在我国，足癣的发病率也相当高。人的足底和趾间没有皮脂腺，从而缺乏抑制皮肤丝状真菌的脂肪酸，生理防御机能较差，而这些部位的皮肤汗腺却很丰富，出汗比较多，加之空气流通性差、局部潮湿温暖，有利于丝状真菌的生长。此外，足底部位皮肤角质层较厚，角质层中的角蛋白是真菌的丰富营养物质，有利于真菌的生长。
足癣治疗药物的选择与菌种的临床类型有关。根据患者皮损表现可将足癣分为角化过度型、丘疹鳞屑型、水疱型和浸渍糜烂型。根据患者的感染部位,可分为趾间型、足跖型和混合型,其中以趾间型最为常见。足癣感染通常较顽固、易反复、用药疗程长、涂抹繁琐,致使依从性差,很难完成规定疗程,治疗复发率居高不下。传统治疗以局部用药为主,根据患者的皮损类型选择不同的剂型。
中医认为，足癣的主要病因是湿热虫毒，由于湿邪粘滞，病情缠绵，反复难愈，日久伤津耗血，癖阻脉络，致血不荣肤。临床辨证一般为血虚风燥型与湿热浸淫型，治疗主要选择杀虫止痒、清热燥湿、养血润肤之剂，常用的配伍方式为杀虫药配伍养血润肤或清热燥湿药。近几十年来，国内学者对中药治疗足癣进行了大量的临床实验研究，包括了单味中药、复方中药以及中西药结合等，其中中药复方涵盖了醋剂、酊剂、膏剂、水溶剂、擦剂等多种剂型。中医药治疗足癣具有抗炎，抗真菌，改善局部血液循环，润肤等作用，在治疗足癣方面取得了一定的进展。
发明内容
综合本领域现有技术以及存在的问题，本发明的目的在于提供一种足癣治疗药物，本发明为纯中药制剂，对足癣具有较好的治疗作用，且无明显毒副作用。
为达到上述目的，本发明是由下列质量比例的原料组成：藿香20-40份、地骨皮10-20份、鸦胆子20-30份、百部20-40份、明矾10-20份、大枫子20-40份、苦参10-30份、黄柏20-30份、蛇床子15-30份、大黄10-20份。本发明给药剂型优选酊剂，用5-10倍75％乙醇浸泡一周后待用，外搽。
具体实施方式
实施例1.本发明由下列质量比例的原料组成：藿香20份、地骨皮20份、鸦胆子30份、百部20份、明矾20份、大枫子40份、苦参10份、黄柏20份、蛇床子30份、大黄10份。
实施例2.本发明由下列质量比例的原料组成：藿香40份、地骨皮10份、鸦胆子20份、百部40份、明矾10份、大枫子20份、苦参30份、黄柏30份、蛇床子15份、大黄20份。

Claims (2)

1.足癣治疗药物，是由下列质量比例的原料组成：藿香20-40份、地骨皮10-20份、鸦胆子20-30份、百部20-40份、明矾10-20份、大枫子20-40份、苦参10-30份、黄柏20-30份、蛇床子15-30份、大黄10-20份。
2.根据权利要求1所述足癣治疗药物，其特征在于：所述给药剂型为酊剂。
CN201510846792.9A 2015-11-28 2015-11-28 足癣治疗药物 Pending CN105343716A (zh)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108721543A (zh) * 2017-04-21 2018-11-02 刘殿文 一种治疗真菌性脚气的药水及制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1316253A (zh) * 2000-04-06 2001-10-10 孔昭苓 治疗脚气病的外用药物及其制备方法
KR101281470B1 (ko) * 2012-12-31 2013-07-03 전상문 피마자를 헥산으로 추출한 피마자유, 운데실렌산, 프로필알코올, 프로필렌글리콜 및 물을 함유하는 무좀 예방 또는 치료용 피부 외용제 조성물

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1316253A (zh) * 2000-04-06 2001-10-10 孔昭苓 治疗脚气病的外用药物及其制备方法
KR101281470B1 (ko) * 2012-12-31 2013-07-03 전상문 피마자를 헥산으로 추출한 피마자유, 운데실렌산, 프로필알코올, 프로필렌글리콜 및 물을 함유하는 무좀 예방 또는 치료용 피부 외용제 조성물

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徐平洲: "《北仑中草药图鉴》", 30 November 2012, 宁波出版社 *
徐树楠: "《中药临床应用大全》", 31 January 1999, 河北科学技术出版社 *
肖国士等: "《中医皮肤科临床妙法绝招解析》", 31 August 2014, 湖南科学技术出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108721543A (zh) * 2017-04-21 2018-11-02 刘殿文 一种治疗真菌性脚气的药水及制备方法

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Application publication date: 20160224