CN105341487A - Chinese herbal medicinal premixed feed for preventing avian influenza of chickens, and preparation method thereof - Google Patents
Chinese herbal medicinal premixed feed for preventing avian influenza of chickens, and preparation method thereof Download PDFInfo
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- CN105341487A CN105341487A CN201510806966.9A CN201510806966A CN105341487A CN 105341487 A CN105341487 A CN 105341487A CN 201510806966 A CN201510806966 A CN 201510806966A CN 105341487 A CN105341487 A CN 105341487A
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Abstract
The invention relates to a feed with medicinal functions, and concretely relates to a Chinese herbal medicinal premixed feed for preventing avian influenza of chickens, and a preparation method thereof. The Chinese herbal medicinal premixed feed comprises, by weight, 2-4 parts of honeysuckle flower, 2-3 parts of Herba Schizonepetae, 2-3 parts of Caulis Perillae, 2-3 parts of Radixet Rhizonma Ephedrae, 2-3 parts of Divaricate Saposhnikovia Root, 2-3 parts of white peony root, 2-4 parts of Radix Platycodonis, 2-4 parts of dry ginger, 2-3 parts of Cyrtomium fortunei, 6-7 parts of isatis root, 6-7 parts of Folium Isatidis and 60-65 parts of rice bran. A result of chicken serum examination of chicken flocks fed with the Chinese herbal medicinal premixed feed in a Hunan Polytechnic of Environment and Biology lab shows that the H1 antibody average level is higher than 410 g<2>.
Description
Technical field
The present invention relates to a kind of feed with medicinal function, specifically relate to a kind of the Chinese herbal medicine premixed feed and the preparation method that prevent avian influenza.
Background technology
People infects bird flu, is the human diseases caused by avian influenza virus.Avian influenza virus, belongs to influenza A virus, according to the pathogenic difference of avian influenza virus to chicken and turkey, is divided into high, medium and low/non-pathogenic three grades.Due to the feature such as hemagglutinin structure of avian influenza virus, nonspecific infection bird, when virus producer reprovision in a replication process, causes structure to change, and obtains the ability infecting people, people just may be caused to infect the generation of bird flu disease.So far find that the avian influenza virus subtype of energy direct infection people has: H5N1, H7N1, H7N2, H7N3, H7N7, H9N2 and H7N9 hypotype.Wherein, highly pathogenic H5N1 hypotype and in March, 2013, the new bird flu H7N9 hypotype of Late Cambrian was particularly noticeable on human body, not only caused the injures and deaths of the mankind, had inflicted heavy losses on poultry farming simultaneously.
At present, both at home and abroad the control measure of poultry bird flu are mainly comprised slaughter, sterilize, bio-safety and vaccine inoculation.The effective measures that birds flu-preventing occurs are vaccine inoculations, when the vaccine inoculated is consistent with clinical popular strains subtype, can obtain desirable protected effect, but when the vaccine of inoculation is different from popular hypotype, just can not adaptive immune protection.Avian influenza virus blood serum subtype is numerous, will producer restructuring during the influenza A mixed infection of different subtype, and form new avian influenza virus, this brings very large difficulty to the development and application of vaccine.Often occur in production practices because the vaccine of inoculation and epidemic isolates hypotype are unworthy of and cause immuning failure.Therefore avian influenza vaccine is only relied on to be difficult to the Occurrence & epidemic controlling bird flu completely.
Chinese Patent Application No. be 201210454545.0 application discloses a kind of preparation method preventing and treating the Chinese herbal medicine active fermentation health promoting liquid of bird flu, described for preventing the probio Chinese herbal medicine active health liquid of chicken infectious disease by rhizome of cyrtomium 5 parts, Radix Isatidis 5 parts, the Radix Astragali 10 parts, radix bupleuri 5 parts, the capsule of weeping forsythia 4 parts, the coptis 5 parts, honeysuckle 5 parts, the root of large-flowered skullcap 5 parts, 4 parts, Radix Glycyrrhizae, 3 parts, mulberry leaf, FLOS CHRYSANTHEMI from Hangzhou of China 5 parts, balloonflower root 2 parts, great burdock achene 1 part, 1 part, the leaf of bamboo, reed rhizome 2 parts, peppermint 5 parts, 2 parts, almond, loguat leaf 5 parts, salt 2 parts, 50 parts, molasses, 820 parts, water, 500000000/ml yeast bacterium 10 parts, 10000000000/milliliter lactic acid bacteria 10 parts, 6000000000/milliliter photosynthetic bacteria 10 parts, 100000000/milliliter Bifidobacterium 10 parts, 8000000000/milliliter bacillus 10 parts composition, it adopts a large amount of probios to strengthen preventive effect.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of the Chinese herbal medicine premixed feed and the preparation method that prevent avian influenza, it with ten simply natural vegetable Chinese herbal medicine composition, be rich in multiple chicken body desired nutritional composition, chicken body immunity can be improved, promote that chicken grows fast, long-term interpolation in feed does not develop immunity to drugs and drug resistance, also without incompatibility.
For solving the problems of the technologies described above, the raw material of the Chinese herbal medicine premixed feed of prevention avian influenza of the present invention comprises following parts by weight component: honeysuckle 2-4 part, schizonepeta 2-3 part, Caulis Perillae 2-3 part, radix ephedrae 2-3 part, windproof 2-3 part, root of herbaceous peony 2-3 part, balloonflower root 2-4 part, rhizoma zingiberis 2-4 part, rhizome of cyrtomium 2-3 part, Radix Isatidis 6-7 part, folium isatidis 6-7 part and rice bran 60-65 part.
Honeysuckle in the present invention, schizonepeta, Caulis Perillae, radix ephedrae, windproof, the root of herbaceous peony, balloonflower root, rhizoma zingiberis, rhizome of cyrtomium, Radix Isatidis and folium isatidis are the medicine after airing.
Preferably, the raw material of the Chinese herbal medicine premixed feed of described prevention avian influenza comprises following parts by weight component: honeysuckle 3 parts, schizonepeta 2.5 parts, Caulis Perillae 2.5 parts, radix ephedrae 2.5 parts, windproof 2.5 parts, the root of herbaceous peony 2.5 parts, balloonflower root 3 parts, rhizoma zingiberis 3 parts, rhizome of cyrtomium 2.5 parts, Radix Isatidis 6.5 parts, folium isatidis 6.5 parts and 63 parts, rice bran.
The present invention also provides a kind of preparation method preventing the Chinese herbal medicine premixed feed of avian influenza, step is: after honeysuckle, schizonepeta, Caulis Perillae, radix ephedrae, windproof, the root of herbaceous peony, balloonflower root, rhizoma zingiberis, rhizome of cyrtomium, Radix Isatidis and folium isatidis being mixed in proportion, fermentation, obtain herbal raw material semi-finished product, then enter oven baking, make the half-finished moisture content of herbal raw material below 8%, then add rice bran, be crushed to 400 ~ 500 orders, obtain the Chinese herbal medicine premixed feed preventing avian influenza.
The present invention also can adopt following steps to obtain, and after honeysuckle, schizonepeta, Caulis Perillae, radix ephedrae, windproof, the root of herbaceous peony, balloonflower root, rhizoma zingiberis, rhizome of cyrtomium, Radix Isatidis, folium isatidis and rice bran mixing, is crushed to 400-500 order and obtains.
Described fermentation temperature is 25 DEG C.
Described baking temperature is 80 DEG C.
Described pulverising step is, is first crushed to 100 ~ 120 orders, and then Ultramicro-powder technique wall cell disruption powder is broken to 400 ~ 500 orders.
After honeysuckle, schizonepeta, Caulis Perillae, radix ephedrae, windproof, the root of herbaceous peony, balloonflower root, rhizoma zingiberis, rhizome of cyrtomium, Radix Isatidis and folium isatidis being mixed in proportion, before fermentation, pulverize, fineness is 50 orders.
In the present invention, described honeysuckle, another name: honeysuckle flower, honeysuckle, two flowers, two precious flowers are caprifoliaceae plant honeysuckle
lonicerajaponicaThunb., lonicera hypoglauca miq
lonicerahypoglaucaMiq., Honeysuckle flower (hair calyx honeysuckle)
loniceraconfusaDC.or hair style honeysuckle
loniceradasystylaRehd.dry flower or the flower just opened of band, early summer the flowers are in blossom put before gather, dry.
In the present invention, described schizonepeta, another name: fragrant chaste tree shepherd's purse, line shepherd's purse, four rib bar wormwood artemisias, false Soviet Union are labiate schizonepeta
schizonepetatenuifoliaBriq.dry aerial parts, the summer, season in autumn two, the flowers are in blossom to top, fringe green time tap, removing impurity, dry.
In the present invention, described Caulis Perillae, another name: caulis perllae is labiate purple perilla
perillafrutescens(L.) Britt.dry stem, autumn taps after fruit maturation, removing impurity, dry, or take advantage of fresh slices, dry.
In the present invention, described radix ephedrae is Ephedraceae plant plait Chinese ephedra
ephedrasinicaStapfor epheday intermedia
ephedraintermediaSchrenketC.A.Mey.dry root and rhizome, autumn end excavates, and removes residual stem, fibrous root and silt, dry.
In the present invention, described windproof, be umbelliferae Saposhnikovia divaricata
saposhnikoviadivaricata(Turcz.) Schischk.dry root.Spring, Qiu Erji excavate the root not taking out scape plant, and removing fibrous root and silt, dry.
In the present invention, the described root of herbaceous peony, another name Chinese herbaceous peony is ranunculaceae plant Chinese herbaceous peony
paeonialactifloraPall.dry root.Summer, Qiu Erji excavate, and clean, and remove end to end and radicula, put in boiling water after boiling rear removing crust or peeling and boil, dry.
In the present invention, described balloonflower root, another name: burden flower, bell, as flower, Dao Laji, are Campanulaceae balloonflower root
platycodongrandiflorum(Jacq.) A.DC.dry root; Spring, Qiu Erji excavate, and clean, and removing fibrous root, takes advantage of and freshly peel off crust or do not remove crust, dry.
In the present invention, described rhizoma zingiberis is zingiber
zingiberofficinaleRosc.dry rhizome, winter excavates, and removing fibrous root and silt, dries or low temperature drying.Take advantage of fresh slices to dry or low temperature drying person is called " dried ginger slice ".
In the present invention, described rhizome of cyrtomium, has another name called thick wood-fern rhizome, cyrtomium fortunei; For Dryopteridaceae plant dryopteris crassirhizoma
dryopteriscrassirhizomaNakaidry rhizome and petiole residue; Autumn excavates, petiole of pruning, fibrous root, and removing silt, dries.
In the present invention, described Radix Isatidis, another name: great Lan root, manyflower glorybower root are cruciferae isatis
isatisindigoticaFort.dry root; Autumn excavates, and removing silt, dries.
In the present invention, described folium isatidis, this product is cruciferae isatis
isatisindigoticaFort.dry leaf.In the summer, divide in season in autumn two and gather for 2 ~ 3 times, removing impurity, dries.
In the step of the preparation method of the Chinese herbal medicine premixed feed of prevention avian influenza of the present invention, the zymophyte that fermentation adopts is Trichoderma, such as trichoderma viride
trichodermaviride(buying from Ke Shuo bio tech ltd, Jining) or trichoderma harzianum (
trichodermaharzianum), be such as deposited in China General Microbiological culture presevation administrative center and deposit number is: the Trichoderma of CGMCCN0.2634.What adopt is normal fermentation step, and solid fermentation, those skilled in the art know concrete operations.
The invention has the beneficial effects as follows, the present invention according to The Yellow Emperor's Canon of Internal Medicine and Ming Dynasty Li Shizhen (1518-1593 A.D.) this herbal be basic, adopt modern biotechnology fermentation technique and nanometer technology, through triennium, test is fed in spring, the poultry examination of season in winter two, and successfully the Chinese herbal premix formula can eliminating avian influenza virus in chicken body is selected in examination.Chicken group on probation is through the chicken serum inspection of Hunan laboratory of environmental institute, and H1 antibody average level is higher than 410g
2, chicken group is fed in 3 years 15 times examinations none generation bird flu disease of totally three ten thousand plumages.
Detailed description of the invention
Embodiment 1
The preparation method of the Chinese herbal medicine premixed feed of prevention avian influenza
By honeysuckle 3kg, schizonepeta 2.5kg, Caulis Perillae 2.5kg, radix ephedrae 2.5kg, windproof 2.5kg, root of herbaceous peony 2.5kg, balloonflower root 3kg, rhizoma zingiberis 3kg, rhizome of cyrtomium 2.5kg, Radix Isatidis 6.5kg, through bio-fermentation process after folium isatidis 6.5kg mixes, keep the fermentation in three days of 25 DEG C of constant temperature, obtain herbal raw material semi-finished product, then enter oven 80 DEG C of constant temperature and keep one hour, make herbal raw material semi-finished product moisture content below 8%, add 63% carrier rice bran again, through first operation meal to 100 ~ 120 order, and then be broken to 400 ~ 500 orders through Ultramicro-powder technique wall cell disruption powder, finally obtain finished product.
The idiographic flow of described zymotechnique is: the expansion first carrying out bacterial classification is cultivated, and obtains seed culture fluid; Then pulverize after honeysuckle 3kg, schizonepeta 2.5kg, Caulis Perillae 2.5kg, radix ephedrae 2.5kg, windproof 2.5kg, root of herbaceous peony 2.5kg, balloonflower root 3kg, rhizoma zingiberis 3kg, rhizome of cyrtomium 2.5kg, Radix Isatidis 6.5kg and folium isatidis 6.5k being mixed, add suitable quantity of water, add after sterilization expand cultivate seed culture fluid, bacterial classification select trichoderma harzianum (
trichodermaharzianum), deposit number is: CGMCCN0.2634.Inoculum concentration is 10%, and fermentation temperature remains between 25 degree, and fermentation overall process is 24-30 hour, and anaerobic fermentation obtains herbal raw material semi-finished product.
Embodiment 2
The preparation method of the Chinese herbal medicine premixed feed of prevention avian influenza
Through bio-fermentation process after honeysuckle 2kg, schizonepeta 3kg, Caulis Perillae 2kg, radix ephedrae 3kg, windproof 3kg, root of herbaceous peony 3kg, balloonflower root 4kg, rhizoma zingiberis 2kg, rhizome of cyrtomium 3kg, Radix Isatidis 6kg, folium isatidis 7kg are mixed, keep the fermentation in three days of 25 DEG C of constant temperature, obtain herbal raw material semi-finished product, then enter oven 80 DEG C of constant temperature and keep one hour, make herbal raw material semi-finished product moisture content below 8%, add 63% carrier rice bran again, through first operation meal to 100 ~ 120 order, and then be broken to 400 ~ 500 orders through Ultramicro-powder technique wall cell disruption powder, finally obtain finished product.Zymotechnique is with embodiment 1.
Embodiment 3
The preparation method of the Chinese herbal medicine premixed feed of prevention avian influenza
Honeysuckle 2kg, schizonepeta 3kg, Caulis Perillae 2kg, radix ephedrae 3kg, windproof 3kg, root of herbaceous peony 3kg, balloonflower root 4kg, rhizoma zingiberis 2kg, rhizome of cyrtomium 3kg, Radix Isatidis 6kg, folium isatidis 7kg and rice bran 63kg are mixed, is crushed to 400-500 order and obtains.
Embodiment 4
The using method of birds flu-preventing
Be added in daily chicken feed by the Chinese herbal medicine premixed feed of prevention avian influenza of the present invention, adding proportion controls at 0.4-0.9%, and drinking-water adds 0.2-0.6%, stirs.
Experimental group adopts the Chinese herbal medicine premixed feed of prevention avian influenza of the present invention to feed chicken 20,000, average nursing 40 days.Control group does not adopt the Chinese herbal medicine premixed feed of prevention avian influenza of the present invention, feeds chicken 10,000, average nursing 40 days.Test group every weightening finish 242.5 gram average than control group.At bird flu epidemic period, test group 0 morbidity, protective rate 100%, control group falls ill 1723, and the incidence of disease is 17.23%.
Embodiment 5
Contrast test
Feed chicken in bird flu height region of disease according to the method for embodiment 3, use the Chinese herbal medicine premixed feed of the prevention avian influenza of embodiments of the invention 1 as experimental group 1, feed chicken 1000; Use Chinese Patent Application No. be the product of 201210454545.0 as experimental group 2, feed chicken 1000; Use daily chicken feed as a control group, feed chicken 1000, the health status of other conditions such as chicken and size etc. are identical.Found that, the morbidity of experimental group 10, the incidence of disease 0%; Experimental group 2 falls ill 197, the incidence of disease 19.7%; Control group falls ill 374, the incidence of disease 37.5%.
Those of ordinary skill in the field are to be understood that: the foregoing is only specific embodiments of the invention; be not limited to the present invention; within the spirit and principles in the present invention all, any amendment made, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (6)
1. one kind is prevented the Chinese herbal medicine premixed feed of avian influenza, it is characterized in that, the raw material of the Chinese herbal medicine premixed feed of described prevention avian influenza comprises following parts by weight component: honeysuckle 2-4 part, schizonepeta 2-3 part, Caulis Perillae 2-3 part, radix ephedrae 2-3 part, windproof 2-3 part, root of herbaceous peony 2-3 part, balloonflower root 2-4 part, rhizoma zingiberis 2-4 part, rhizome of cyrtomium 2-3 part, Radix Isatidis 6-7 part, folium isatidis 6-7 part and rice bran 60-65 part.
2. the Chinese herbal medicine premixed feed of prevention avian influenza as claimed in claim 1, it is characterized in that, the raw material of the Chinese herbal medicine premixed feed of described prevention avian influenza comprises following parts by weight component: honeysuckle 3 parts, schizonepeta 2.5 parts, Caulis Perillae 2.5 parts, radix ephedrae 2.5 parts, windproof 2.5 parts, the root of herbaceous peony 2.5 parts, balloonflower root 3 parts, rhizoma zingiberis 3 parts, rhizome of cyrtomium 2.5 parts, Radix Isatidis 6.5 parts, folium isatidis 6.5 parts and 63 parts, rice bran.
3. one kind is prevented the preparation method of the Chinese herbal medicine premixed feed of avian influenza as claimed in claim 1 or 2, it is characterized in that, step is: after honeysuckle, schizonepeta, Caulis Perillae, radix ephedrae, windproof, the root of herbaceous peony, balloonflower root, rhizoma zingiberis, rhizome of cyrtomium, Radix Isatidis and folium isatidis being mixed in proportion, fermentation, obtain herbal raw material semi-finished product, then oven baking is entered, make the half-finished moisture content of herbal raw material below 8%, add rice bran again, be crushed to 400 ~ 500 orders, obtain the Chinese herbal medicine premixed feed preventing avian influenza.
4. preparation method as claimed in claim 3, it is characterized in that, described fermentation temperature is 25 DEG C.
5. the preparation method as described in claim 3 or 4, is characterized in that, described baking temperature is 80 DEG C.
6. the preparation method as described in claim 3 or 4, is characterized in that, described pulverising step is, is first crushed to 100 ~ 120 orders, and then Ultramicro-powder technique wall cell disruption powder is broken to 400 ~ 500 orders.
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| CN201510806966.9A CN105341487A (en) | 2015-11-22 | 2015-11-22 | Chinese herbal medicinal premixed feed for preventing avian influenza of chickens, and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106173462A (en) * | 2016-07-12 | 2016-12-07 | 重庆旭源农业开发有限公司 | Poultry feedstuff |
| CN107349420A (en) * | 2017-06-01 | 2017-11-17 | 烟台民生家禽养殖专业合作社 | A kind of composition, preparation method and application method for being used to prevent and treat contagious catarrh |
| CN113398203A (en) * | 2021-07-10 | 2021-09-17 | 四川成康动物药业有限公司 | Traditional Chinese medicine fermentation product for swine influenza and preparation method and device thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908549A (en) * | 2012-11-14 | 2013-02-06 | 蒋常德 | Chinese herbal medicine active fermentation health care liquid for preventing and treating bird flu and preparation method of same |
-
2015
- 2015-11-22 CN CN201510806966.9A patent/CN105341487A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102908549A (en) * | 2012-11-14 | 2013-02-06 | 蒋常德 | Chinese herbal medicine active fermentation health care liquid for preventing and treating bird flu and preparation method of same |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106173462A (en) * | 2016-07-12 | 2016-12-07 | 重庆旭源农业开发有限公司 | Poultry feedstuff |
| CN107349420A (en) * | 2017-06-01 | 2017-11-17 | 烟台民生家禽养殖专业合作社 | A kind of composition, preparation method and application method for being used to prevent and treat contagious catarrh |
| CN113398203A (en) * | 2021-07-10 | 2021-09-17 | 四川成康动物药业有限公司 | Traditional Chinese medicine fermentation product for swine influenza and preparation method and device thereof |
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Application publication date: 20160224 |