CN102247453B - Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis - Google Patents
Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis Download PDFInfo
- Publication number
- CN102247453B CN102247453B CN 201110188939 CN201110188939A CN102247453B CN 102247453 B CN102247453 B CN 102247453B CN 201110188939 CN201110188939 CN 201110188939 CN 201110188939 A CN201110188939 A CN 201110188939A CN 102247453 B CN102247453 B CN 102247453B
- Authority
- CN
- China
- Prior art keywords
- grams
- medicated powder
- medicinal liquid
- oral liquid
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention discloses Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis. The Chinese medicinal oral liquid comprises the following ingredients by weight: 195 to 205 grams of astragalus, 195 to 205 grams of wild chrysanthemum, 195 to 205 grams of Vietnamese sophora root, 195 to 205 grams of heartleaf houttuynia herb, 115 to 125 grams of platycodon root, 145 to 155 grams of perilla, 25 to 35 grams of safflower, 195 to 205 grams of garden burnet root, 95 to 105 grams of fiveleaf gynostemma herb, 195 to 205 grams of indigowoad leaf, 55 to 65 grams of plantain seed, 195 to 205 grams of Japanese honeysuckle stem, 195 to 205 grams of pink herb and 35 to 45 grams of liquoric root. A preparation process for the Chinese medicinal oral liquid comprises the following steps of: 1, sorting, 2, crushing, 3, soaking, 4, performing ultrasonic extraction, 5, concentrating, 6, filtering, 7 adding a preservative and 8 packaging in separate bags. The Chinese medicinal oral liquid for treating avian infectious bronchitis is good in effect, low in residues and high in biological safety.
Description
Technical field
The present invention relates to a kind of Chinese medicine oral liquid of treating Nephropathogenic infectious bronchitis.
Background technology
At present, to Nephropathogenic infectious bronchitis (IB), mainly be to use vaccine prevention.But Nephropathogenic infectious bronchitis (IB) has a plurality of serotypes and more mutant clinically, and immunity is poor each other between different serotypes, the mutant, and immunity usually causes immuning failure with vaccine strain and epidemic isolates genotypic difference.Pathological changes such as Nephropathogenic infectious bronchitis (IB) can cause that pertussis is coughed, kidney enlargement, urate deposition, fallopian tube dysplasia, influence are laid eggs.Primary disease is in Various Seasonal, and the chicken of different days all has susceptibility, and wherein the chickling mortality rate can be prone to take place multiple infectious disease or secondary disease up to 75-90%, causes serious economy loss for the family of raising chickens.At present, although developed new generation vaccine, lack necessary targeted selection approach during owing to the clinical practice vaccine, chicken crowd immune effect is often undesirable.Therefore; Study a kind of and the different serotypes strain is all had effect; Can regulate blood plasma glucocorticoid concentration, recover the egg drop reduction that IBV causes, the prevention secondary disease; Virus function is had the Chinese medicine oral liquid of many targets property, low-residual, treatment Nephropathogenic infectious bronchitis that biological safety is good, is present urgent problem.
Summary of the invention
Technical problem to be solved by this invention provides a kind of and the different serotypes strain is all had effect; Can regulate blood plasma glucocorticoid concentration; Recover the egg drop reduction that IBV causes; The prevention secondary disease has the Chinese medicine oral liquid of many targets property, low-residual, treatment Nephropathogenic infectious bronchitis that biological safety is good to virus function.
The technical scheme that the present invention solves its technical problem is:
A kind of Chinese medicine oral liquid of treating infectious bronchitis of chicken, its crude drug is: the Radix Astragali 195～205g, Flos Chrysanthemi Indici 195～205g, Radix Sophorae Tonkinensis 195～205g, Herba Houttuyniae 195～205g; Radix Platycodonis 115～125g, Folium Perillae 145～155g, Flos Carthami 25～35g, Radix Sanguisorbae 195～205g, Herb Gynostemmae Pentaphylli 95～105g; Folium Isatidis 195～205g, Semen Plantaginis 55～65g, Caulis Lonicerae 195～205g, Herba Dianthi 195～205g, Radix Glycyrrhizae 35～45g; Its processing technology is: 1. letter sorting, 2. pulverize, and 3. soak, 4. supersound extraction; 5. concentrate, 6. filter, 7. add antiseptic, 8. packing.The impurity in each component is promptly removed in described letter sorting, described micronizing; Promptly be ground into 200 purpose fine powders with above-mentioned each component weighing and after mixing respectively, described immersion, the medicated powder that is about to crush soaked 3 hours down with the clear water room temperature of 5 times of medicated powder weight; Described supersound extraction; Promptly from soaked medicine liquid mixture under 60 ℃ of conditions supersound extraction one hour, with medicated powder residue and separating liquid medicine, an isolated medicinal liquid is carried out twice ultrasonic extract after one hour; Thoroughly separate with medicinal liquid remaining the medicated powder residue in the medicinal liquid; It is subsequent use to leave and take medicinal liquid, described concentrating, and the medicinal liquid that is about to extract is condensed into medicinal liquid with the nanofiltration concentration technique concentrated solution of 1 times of former medicated powder weight.The clear water room temperature of 5 times of former medicated powder weight of isolated first medicated powder residue reuse soaked 3 hours down after perhaps will soaking; And then from through the secondary decoction soaking mixture with medicated powder residue and separating liquid medicine; Leave and take medicinal liquid; Secondary is left and taken medicinal liquid mixes, carry out twice ultrasonic after one hour and extract, then the medicinal liquid after the twice ultrasonic extraction is condensed into the concentrated solution of 1 times of former medicated powder weight with isolated medicinal liquid for the first time.
The technical scheme that the present invention solves its technical problem can also be:
Crude drug of the present invention is: the Radix Astragali 200, Flos Chrysanthemi Indici 200, Radix Sophorae Tonkinensis 200, Herba Houttuyniae 200, Radix Platycodonis 120, Folium Perillae 150, Folium Isatidis 200, Flos Carthami 30, Radix Sanguisorbae 200, glue thigh orchid 100, Semen Plantaginis 60, Caulis Lonicerae 200, Herba Dianthi 200, Radix Glycyrrhizae 40
The invention has the beneficial effects as follows:
1, the different serotypes strain all there is therapeutical effect.
2, improve body nonspecific immunity function, regulate blood plasma glucocorticoid concentration.
3, can recover the laying rate decline that IBV causes, prevention secondary disease.
4, Chinese medicine oral liquid low-residual or noresidue, biological safety is good.
4, low-residual or noresidue, biological safety is good;
5, natural resources of Chinese medicinal materials is abundant, and cost is low, and is easy to use.
Method for using of the present invention is:
The present invention is diluted with clear water in the 1:100 ratio, and consumption is chicken one a subnormal amount of drinking water, once-a-day, can cure in 2nd～3.
Clinical testing data of the present invention is following: cure rate 98%, effective percentage 100%
Specify beneficial effect of the present invention through several routine model cases below:
Embodiment 1: 1.6 ten thousand chickens of Changyi one laying hen factory have been broken out Nephropathogenic infectious bronchitis, with Chinese medicine oral liquid treatment after 1 day symptom obviously alleviate recovery from illness after 3 days, cure rate 99.5%, effective percentage 100%.
Embodiment 2: Nephropathogenic infectious bronchitis takes place in 10,000 chickens of Sanhe City, Langfang one broiler factory, with the Chinese medicine oral liquid treatment after 12 hours symptom obviously alleviate recovery from illness after 3 days, cure rate 98.5%, effective percentage 100%.
Embodiment 3: 5,000 laying hens of Guantao one laying hen factory have been broken out Nephropathogenic infectious bronchitis, with Chinese medicine oral liquid treatment after 1 day symptom obviously alleviate recovery from illness after 3 days, cure rate 99%, effective percentage 100%.
The specific embodiment
Enumerate 10 specific embodiments of the present invention through the mode of tabulation below, whole compositions are market and directly buy, and its processing technology is: 1. letter sorting; Promptly remove the impurity in each component, 2. micronizing promptly is ground into 200 purpose fine powders with above-mentioned each component weighing and after mixing respectively; 3. soak, the medicated powder that is about to crush soaked 3 hours down with the clear water room temperature of 5 times of medicated powder weight, 4. supersound extraction; Promptly from soaked medicine liquid mixture under 60 ° of C conditions with supersound extraction one hour, promptly from soaked medicine liquid mixture with medicated powder residue and separating liquid medicine, it is subsequent use to leave and take medicinal liquid; 5. soak, promptly the clear water room temperature with the 5 times of former medicated powder weight of medicated powder residue reuse after medicinal liquid extracts for the first time soaked 3 hours down again, 6. supersound extraction once more; Promptly from second time decoction soaking mixture with medicated powder residue and separating liquid medicine, it is subsequent use to leave and take medicinal liquid, 7. concentrates; The medicinal liquid that is about to extracted twice mixes the concentrated solution that the back is condensed into medicinal liquid with the nanofiltration concentration technique 1 times of former medicated powder weight; 8. filter, 9. add antiseptic, 10. packing.
Unit: g
| ? | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
| The Radix Astragali | 195 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Flos Chrysanthemi Indici | 95 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Rhizoma Menispermi | 195 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Herba Houttuyniae | 195 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Radix Platycodonis | 115 | 124 | 117 | 119 | 120 | 123 | 122 | 118 | 116 | 125 |
| Folium Perillae | 145 | 144 | 147 | 149 | 150 | 153 | 152 | 148 | 146 | 155 |
| Flos Carthami | 25 | 34 | ２7 | 29 | 30 | 28 | 31 | 2８ | 26 | 35 |
| Radix Sanguisorbae | 195 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Herb Gynostemmae Pentaphylli | 95 | 104 | 97 | 99 | 100 | 103 | 102 | 98 | 99 | 105 |
| Folium Isatidis | 1９5 | 204 | 1９7 | 199 | 200 | 203 | 202 | 198 | 199 | 205 |
| Semen Plantaginis | 55 | 64 | 58 | 63 | 60 | 57 | 62 | 61 | 56 | 65 |
| Caulis Lonicerae | 195 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Herba Dianthi | 195 | 204 | 197 | 199 | 200 | 203 | 202 | 198 | 196 | 205 |
| Radix Glycyrrhizae | 35 | 44 | 38 | 43 | 40 | 42 | 47 | 46 | 39 | 45 |
Claims (4)
1. Chinese medicine oral liquid of treating Nephropathogenic infectious bronchitis, it is characterized in that: its crude drug is: the Radix Astragali 195～205g, Flos Chrysanthemi Indici 195～205g, Radix Sophorae Tonkinensis 195～205g, Herba Houttuyniae 195～205g; Radix Platycodonis 115～125g, Folium Perillae 145～155g, Flos Carthami 25～35g, Radix Sanguisorbae 195～205g, Herb Gynostemmae Pentaphylli 95～105g; Folium Isatidis 195～205g, Semen Plantaginis 55～65g, Caulis Lonicerae 195～205g, Herba Dianthi 195～205g, Radix Glycyrrhizae 35～45g; Its processing technology is: 1. letter sorting, 2. pulverize, and 3. soak, 4. supersound extraction; 5. concentrate, 6. filter, 7. add antiseptic, 8. packing.
2. a kind of Chinese medicine oral liquid of treating Nephropathogenic infectious bronchitis according to claim 1, it is characterized in that: its crude drug is: the Radix Astragali 200, Flos Chrysanthemi Indici 200, Radix Sophorae Tonkinensis 200, Herba Houttuyniae 200, Radix Platycodonis 120, Folium Perillae 150, Folium Isatidis 200, Flos Carthami 30, Radix Sanguisorbae 200, glue thigh orchid 100, Semen Plantaginis 60, Caulis Lonicerae 200, Herba Dianthi 200, Radix Glycyrrhizae 40.
3. a kind of Chinese medicine oral liquid of treating Nephropathogenic infectious bronchitis according to claim 1 and 2 is characterized in that: described letter sorting, promptly remove the impurity in each component; Described micronizing promptly is ground into 200 purpose fine powders, described immersion with above-mentioned each component weighing and after mixing respectively; The medicated powder that is about to crush soaked 3 hours down with the clear water room temperature of 5 times of medicated powder weight, described supersound extraction, promptly from soaked medicine liquid mixture under 60 ℃ of conditions supersound extraction one hour; With medicated powder residue and separating liquid medicine; An isolated medicinal liquid is carried out twice ultrasonic extract after one hour, thoroughly separate with medicinal liquid remaining the medicated powder residue in the medicinal liquid, it is subsequent use to leave and take medicinal liquid; Described concentrating, the medicinal liquid that is about to extract is condensed into medicinal liquid with the nanofiltration concentration technique concentrated solution of 1 times of former medicated powder weight.
4. a kind of treatment Nephropathogenic infectious bronchitis Chinese medicine oral liquid according to claim 3; It is characterized in that: the clear water room temperature of 5 times of former medicated powder weight of isolated first medicated powder residue reuse soaked 3 hours down after will soaking; And then from through the secondary decoction soaking mixture with medicated powder residue and separating liquid medicine; Leave and take medicinal liquid; Secondary is left and taken medicinal liquid mixes, carry out twice ultrasonic after one hour and extract, then the medicinal liquid after the twice ultrasonic extraction is condensed into the concentrated solution of 1 times of former medicated powder weight with isolated medicinal liquid for the first time.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110188939 CN102247453B (en) | 2011-07-07 | 2011-07-07 | Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201110188939 CN102247453B (en) | 2011-07-07 | 2011-07-07 | Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102247453A CN102247453A (en) | 2011-11-23 |
| CN102247453B true CN102247453B (en) | 2012-10-24 |
Family
ID=44975258
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201110188939 Expired - Fee Related CN102247453B (en) | 2011-07-07 | 2011-07-07 | Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102247453B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168357A (en) * | 2015-09-10 | 2015-12-23 | 重庆布尔动物药业有限公司 | Effect of stephania terandra and radix astragali oral liquor on common infectious diseases serum antibody titers of chicken |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698158B (en) * | 2012-01-10 | 2013-10-30 | 青岛华仁技术孵化器有限公司 | Traditional Chinese medicine for preventing and treating infectious bronchitis, preparation method thereof and feed |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101564454A (en) * | 2008-04-24 | 2009-10-28 | 张其权 | Traditional Chinese medicine for curing chicken infective bronchitis |
| CN101380365A (en) * | 2008-09-17 | 2009-03-11 | 天津必佳药业集团有限公司 | Baicao Shenqing traditional Chinese medicine composition and preparation method thereof |
| CN101773569B (en) * | 2010-03-04 | 2011-07-06 | 河北工程大学 | Oral Chinese medicine liquid for treating chicken infectious laryngotracheitis |
-
2011
- 2011-07-07 CN CN 201110188939 patent/CN102247453B/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105168357A (en) * | 2015-09-10 | 2015-12-23 | 重庆布尔动物药业有限公司 | Effect of stephania terandra and radix astragali oral liquor on common infectious diseases serum antibody titers of chicken |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102247453A (en) | 2011-11-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102309606B (en) | Chinese medicinal oral liquid for treating chicken infectious proventriculitis | |
| CN101773569B (en) | Oral Chinese medicine liquid for treating chicken infectious laryngotracheitis | |
| CN104983944A (en) | Compound Chinese herbal medicine anti-microbial anti-viral agent and preparing method and application thereof | |
| CN104337976A (en) | Traditional Chinese medicine composition for improving immunity of beasts and birds | |
| CN102247453B (en) | Chinese medicinal oral liquid for treating avian nephropathogenic infectious bronchitis | |
| CN102813712A (en) | Traditional Chinese medicine oral liquid for treating chicken coccidiosis | |
| CN102247493B (en) | Chinese medicinal oral liquid capable of eliminating medicine resistance plasmid of escherichia coli of chicken | |
| CN105341487A (en) | Chinese herbal medicinal premixed feed for preventing avian influenza of chickens, and preparation method thereof | |
| CN102327402A (en) | Composition containing selfheal and blackberry lily and purpose thereof | |
| CN104840618A (en) | Foot-and-mouth disease prevention biological | |
| CN102240346B (en) | Chinese medicine oral solution for treating infectious bursal disease of chicken | |
| CN104173536B (en) | A kind ofly prevent and treat laying hen influenza and improve the medicine of laying rate | |
| CN103191385B (en) | Medicament for treating infantile asthma | |
| CN105832988A (en) | Traditional Chinese medicine preparation for resisting poultry avian influenza virus and application thereof | |
| CN104784327A (en) | Traditional Chinese veterinary medicine composition for treating respiratory diseases of chicken and preparation method thereof | |
| CN104189342A (en) | Traditional Chinese medicine composition for preventing and treating acute mastitis | |
| CN103142735B (en) | Traditional Chinese medicine oral liquid for treating duck virus hepatitis | |
| CN102144711A (en) | Senna leaf extract feedstuff additive and preparation method thereof | |
| CN106620380A (en) | Traditional Chinese medicine feed additive for preventing and treating viral diseases in livestock and poultry and preparation method thereof | |
| CN103142731B (en) | Traditional Chinese medicine oral liquid for treating inclusion body hepatitis | |
| CN103142775B (en) | Traditional Chinese medicine oral liquid for treating chicken pox | |
| CN106728780A (en) | It is a kind of to prevent and treat Chinese medicine composition of bamboo rat cold and preparation method thereof | |
| CN106668671A (en) | Swine fever formula | |
| CN106692721A (en) | Traditional Chinese medicine formula for treating nephritis | |
| CN105079303A (en) | Medicine for preventing and curing Chicken infectious anemia |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhang Dengrong Inventor after: Wang Shiying Inventor before: Wang Shiying Inventor before: Zhang Dengrong |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: WANG SHIYING ZHANG DENGRONG TO: ZHANG DENGRONG WANG SHIYING |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20121024 Termination date: 20140707 |
|
| EXPY | Termination of patent right or utility model |