CN105327058A - Anti-infection heal-promoting ointment for diabetic feet and preparation method thereof - Google Patents
Anti-infection heal-promoting ointment for diabetic feet and preparation method thereof Download PDFInfo
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- CN105327058A CN105327058A CN201510730724.6A CN201510730724A CN105327058A CN 105327058 A CN105327058 A CN 105327058A CN 201510730724 A CN201510730724 A CN 201510730724A CN 105327058 A CN105327058 A CN 105327058A
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Abstract
The invention discloses anti-infection heal-promoting ointment for diabetic feet and a preparation method thereof. The anti-infection heal-promoting ointment for the diabetic feet is prepared from, by weight, 5-20 g of milkvetch roots, 2-5 adult ground beetles, 5-15 g of honeysuckle flowers, 3-8 g of fructus schisandrae chinensis, 6-13 g of rhizoma polygoni cuspidati, 3-6 g of resina draconis, 8-15 g of lychee seeds, 4-9 g of common fibraurea stems, 5-13 g of sulfanilamide silver powder and 1-3 parts of sesame oil. According to the anti-infection heal-promoting ointment for the diabetic feet and the preparation method thereof, the raw materials in the formula all accord with national or local standard regulations, the raw materials are general and appropriate in cost, and the preparation process is simple and convenient. Sterilization and infection resisting can be effectively achieved, a moist environment of the wound surface is maintained, regeneration of wound skins and soft tissue is facilitated, healing of the diabetes foot wound surface is accelerated, and the amputation rate of a patient is decreased.
Description
Technical field
The present invention relates to technical field of Chinese medicine, particularly relate to a kind of diabetic foot infection promoting healing unguentum and preparation method thereof.
Background technology
Diabetic foot is due to diabetics periphery microangiopathies, stenosis occlusion, arterial perfusion is not enough, cause organizing microcirculation disturbance, merge peripheral neuropathy simultaneously, feel to go down, thus cause destruction and the teratogenesis of foot soft tissue and osteoarticular system, the final morbid state that dermal chronic ulcer and extremity gangrene occur.Diabetic foot is the common severe complication of diabetics, is also the one of the main reasons that patient is disabled.The generation of diabetic foot and chronic peripheral angiopathy and peripheral neuropathy closely related.First, diabetics makes lower extremity dysesthesias due to neuropathy, lacks protection mechanism, easily occurs damage under long-term stress effect.Secondly, because long term hyperglycemia causes arteriosclerosis to occur and microcirculation disturbance, local organization ischemia and malnutrition, skin and soft tissue atrophy, tissue regeneration ability is poor.In addition, owing to organizing interior sugar content high, appropriate bacterial grows, and leukocytes phagocytic ability reduces, resistance is poor, and therefore bacteriological infection incidence rate is high, and small wound all can cause dermal chronic ulcer to be formed, course of disease protracted course of disease, finally involves osteoarthrosis, usually needs amputation even threat to life time serious.The difficult point of diabetic foot comprises: how to improve local blood circulation; How infection control; How to stimulate tissue regeneration.And existing various in, Western medicine drug all cannot take into account above problem simultaneously, therefore clinical efficacy is limited.In view of above defect, be necessary to design a kind of diabetic foot infection promoting healing unguentum and preparation method thereof in fact.
Summary of the invention
One is the object of the present invention is to provide to treat diabetic foot infection promoting healing unguentum.This diabetic foot infection promoting healing unguentum can effective infection, improves local blood circulation and promotes that wound tissue heals and recover.
For solving the problems of the technologies described above, technical scheme of the present invention is: a kind of diabetic foot infection promoting healing unguentum.It is made up of the raw material of following weight: Radix Astragali 5-20g, eupolyphaga adult 2-5, Flos Lonicerae 5-15g, Fructus Schisandrae Chinensis 3-8g, Rhizoma Polygoni Cuspidati 6-13g, Sanguis Draxonis 3-6g, Semen Litchi 8-15g, Caulis Fibraureae 4-9g, sulfanilamide argentum powder 5-13g, Oleum Sesami 1-3kg.
Further, the preparation method of diabetic foot infection promoting healing unguentum is carried out according to the following steps:
(1) dried is carried out to eupolyphaga adult, make its thorough mummification;
(2) said medicine is all ground to except Oleum Sesami the powder particle of 0.2-0.5mm;
(3) Oleum Sesami is heated to fluidized state, continues 15 minutes;
(4) in the Oleum Sesami of fluidized state, add the powder of the medicines such as the Radix Astragali, eupolyphaga adult, Flos Lonicerae, Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Sanguis Draxonis, Semen Litchi, Caulis Fibraureae respectively;
(5) stop heating Oleum Sesami, and wait for that Oleum Sesami is down to room temperature 20 DEG C;
(6) in cooled Oleum Sesami, sulfanilamide argentum powder is added;
(7) Oleum Sesami is reheated, make Oleum Sesami temperature reach 40-60 DEG C, and continue 3-5 minute;
(8) Oleum Sesami is cooled, be cooled to temperature 25 DEG C-38 DEG C;
(9) keep 25 DEG C-38 DEG C, leave standstill 48-72 hour;
(10) dispel unnecessary Oleum Sesami, only retain the mixture of medicine and Oleum Sesami;
(11) medicine and Oleum Sesami mixture are loaded stand-by according to the standard sub-bottle of every 50-60g.
Further, during use, the Oleum Sesami in bottle and medicament mixed body are heated to 10 DEG C-18 DEG C, then smear to foot affected part.
The drug effect of key agents involved in the present invention is as follows:
The Radix Astragali: have QI invigorating lung heat clearing, Fructus Alpiniae Oxyphyllae nourished heart, promoting blood circulation and hemostasis, dissipating blood stasis for subsidence of swelling, all poison burst after, closing in granulation promoting, effect of growth promoting effects.
Eupolyphaga adult: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, traumatic injury, congestion swells and ache, lump in the abdomen mass in the abdomen.
Flos Lonicerae: heat-clearing and toxic substances removing, for ulcer sores, laryngopharynx swelling and pain, noxious dampness, has antibacterial and anti-inflammation functions.Also can be used for the toxic action reducing other Chinese medicines.
Fructus Schisandrae Chinensis: energy enhancing body, to the defence capability of nonspecific stimulation, improves immunologic function.Its immersion all has inhibitory action to anthrax bacillus, staphylococcus aureus, Staphylococcus albus, Bacillus typhi etc.
Rhizoma Polygoni Cuspidati: expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.
Sanguis Draxonis: there is analgesic therapy of invigorating blood circulation, removing stasis to stop bleeding, effect of promoting tissue regeneration and ulcer healing.For traumatic injury, trusted subordinate's stasis of blood pain, traumatic hemorrhage, skin infection is not held back.
Semen Litchi: sweet, micro-hardship, temperature.Promoting QI to circulate and dispersing the agglomeration of the pathogens, cold-dispelling pain-relieving.
Caulis Fibraureae: heat-clearing and toxic substances removing; Dampness removing.For acute tonsillitis, pharyngolaryngitis, gastroenteritis, dysentery, furuncle, burn and scald.
Sulfanilamide argentum powder: the folic acid generation of interference antibacterial penetrates, the growth of effective anti-bacteria, breeding.
Oleum Sesami: this product nature and flavor are sweet, cool, has effect of loosening bowel to relieve constipation, removing toxic substances and promoting granulation.Record according in Compendium of Material Medica: " have moisturize, detoxify, pain relieving, detumescence merit.
Compared with prior art, this diabetic foot infection promoting healing unguentum and preparation method thereof, in formula, various raw material all meets country or provincial standard regulation, medicine material prevailing price is suitable, and preparation process is simple and convenient, and excellent curative, effectively can be sterilized infection, promote the skin soft tissue regeneration of wound place, accelerate healing, and reduce amputation rate.
Accompanying drawing explanation
Fig. 1 is preparation flow figure of the present invention
Detailed description of the invention
Hereinafter, set forth multiple specific detail, to provide the thorough understanding to the concept forming described embodiment basis.But to one skilled in the art, embodiment described obviously can be put into practice when not have in these specific detail some or all.
Embodiment 1
The diabetic foot infection promoting healing unguentum that the present embodiment is enumerated, is made up of the raw material of following weight: Radix Astragali 13g, eupolyphaga adult 4, Flos Lonicerae 10g, Fructus Schisandrae Chinensis 5g, Rhizoma Polygoni Cuspidati 10g, Sanguis Draxonis 4g, Semen Litchi 12g, Caulis Fibraureae 6g, sulfanilamide argentum powder 9g, Oleum Sesami 2kg.
Make as follows, first dried is carried out to eupolyphaga adult, make its thorough mummification, again the whole medicines except Oleum Sesami are ground to the powder particle of 0.2-0.5mm, again Oleum Sesami is heated to fluidized state, and continue 15 minutes, the Radix Astragali is added respectively again in the Oleum Sesami of fluidized state, eupolyphaga adult, Flos Lonicerae, Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Sanguis Draxonis, Semen Litchi, the powder of the medicines such as Caulis Fibraureae, stop again heating Oleum Sesami, and wait for that Oleum Sesami is down to room temperature 20 DEG C, sulfanilamide argentum powder is added again in cooled Oleum Sesami, again Oleum Sesami is reheated, Oleum Sesami temperature is made to reach 40-60 DEG C, and continue 3-5 minute, again Oleum Sesami is cooled, be cooled to temperature 25 DEG C-38 DEG C, keep 25 DEG C-38 DEG C again, leave standstill 48-72 hour, dispel unnecessary Oleum Sesami again, only retain the mixture of medicine and Oleum Sesami, again medicine and Oleum Sesami mixture are loaded stand-by according to the standard sub-bottle of every 50-60g.When above-mentioned diabetic foot infection promoting healing unguentum uses, the Oleum Sesami in bottle and medicament mixed body are heated to 10 DEG C-18 DEG C, then smear to foot affected part.
This diabetic foot infection promoting healing unguentum and preparation method thereof, in formula, various raw material all meets country or provincial standard regulation, medicine material prevailing price is suitable, preparation process is simple and convenient, and excellent curative, can effectively sterilize infection, promotes wound place skin tissue regeneration, improve healing rate, and reduce amputation rate.
Embodiment 2
The diabetic foot infection promoting healing unguentum that the present embodiment is enumerated, is made up of the raw material of following weight: Radix Astragali 5g, eupolyphaga adult 2, Flos Lonicerae 5g, Fructus Schisandrae Chinensis 3g, Rhizoma Polygoni Cuspidati 6g, Sanguis Draxonis 3g, Semen Litchi 8g, Caulis Fibraureae 4g, sulfanilamide argentum powder 5g, Oleum Sesami 1kg.
Make as follows, first dried is carried out to eupolyphaga adult, make its thorough mummification, again the whole medicines except Oleum Sesami are ground to the powder particle of 0.2-0.5mm, again Oleum Sesami is heated to fluidized state, and continue 15 minutes, the Radix Astragali is added respectively again in the Oleum Sesami of fluidized state, eupolyphaga adult, Flos Lonicerae, Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Sanguis Draxonis, Semen Litchi, the powder of the medicines such as Caulis Fibraureae, stop again heating Oleum Sesami, and wait for that Oleum Sesami is down to room temperature 20 DEG C, sulfanilamide argentum powder is added again in cooled Oleum Sesami, again Oleum Sesami is reheated, Oleum Sesami temperature is made to reach 40-60 DEG C, and continue 3-5 minute, again Oleum Sesami is cooled, be cooled to temperature 25 DEG C-38 DEG C, keep 25 DEG C-38 DEG C again, leave standstill 48-72 hour, dispel unnecessary Oleum Sesami again, only retain the mixture of medicine and Oleum Sesami, again medicine and Oleum Sesami mixture are loaded stand-by according to the standard sub-bottle of every 50-60g.When above-mentioned diabetic foot infection promoting healing unguentum uses, the Oleum Sesami in bottle and medicament mixed body are heated to 10 DEG C-18 DEG C, then smear to foot affected part.
This diabetic foot infection promoting healing unguentum and preparation method thereof, in formula, various raw medicinal material is the Chinese crude drug meeting country or provincial standard and specify, medicine material prevailing price is suitable, preparation process is simple and convenient, and excellent curative, can effectively sterilize infection, promotes wound place skin regeneration, improve healing rate, reduce amputation rate.
Embodiment 3
The diabetic foot infection promoting healing unguentum that the present embodiment is enumerated, is made up of the raw material of following weight: Radix Astragali 20g, eupolyphaga adult 5, Flos Lonicerae 15g, Fructus Schisandrae Chinensis 8g, Rhizoma Polygoni Cuspidati 13g, Sanguis Draxonis 6g, Semen Litchi 15g, Caulis Fibraureae 9g, sulfanilamide argentum powder 13g, Oleum Sesami 3kg.
Make as follows, first dried is carried out to eupolyphaga adult, make its thorough mummification, again the whole medicines except Oleum Sesami are ground to the powder particle of 0.2-0.5mm, again Oleum Sesami is heated to fluidized state, and continue 15 minutes, the Radix Astragali is added respectively again in the Oleum Sesami of fluidized state, eupolyphaga adult, Flos Lonicerae, Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Sanguis Draxonis, Semen Litchi, the powder of the medicines such as Caulis Fibraureae, stop again heating Oleum Sesami, and wait for that Oleum Sesami is down to room temperature 20 DEG C, sulfanilamide argentum powder is added again in cooled Oleum Sesami, again Oleum Sesami is reheated, Oleum Sesami temperature is made to reach 40-60 DEG C, and continue 3-5 minute, again Oleum Sesami is cooled, be cooled to temperature 25 DEG C-38 DEG C, keep 25 DEG C-38 DEG C again, leave standstill 48-72 hour, dispel unnecessary Oleum Sesami again, only retain the mixture of medicine and Oleum Sesami, again medicine and Oleum Sesami mixture are loaded stand-by according to the standard sub-bottle of every 50-60g.When above-mentioned diabetic foot infection promoting healing unguentum uses, the Oleum Sesami in bottle and medicament mixed body are heated to 10 DEG C-18 DEG C, then smear to foot affected part.
Wang, man, 75 years old.Diabetes 10 years, use insulin glycemic control undesirable, and heel portion occurred more than 4.8 × 3.5cm ulcer October.After the dressing change of conventional local, ulcer has no healing.Use formula ointment embodiment 3 formula of the present invention, after one month, wound surface reduces 65%, 1 treatment next day of continuation, 50 days ulcer healings.
This diabetic foot infection promoting healing unguentum and preparation method thereof, in formula, various raw medicinal material is the Chinese crude drug meeting country or provincial standard and specify, medicine material prevailing price is suitable, preparation process is simple and convenient, and excellent curative, can effectively sterilize infection, promotes wound place skin regeneration, improve healing rate, reduce amputation rate.
The present invention is not limited to above-mentioned concrete embodiment, and those of ordinary skill in the art is from above-mentioned design, and without performing creative labour, all conversion made, all drop within protection scope of the present invention.
Claims (3)
1. a diabetic foot infection promoting healing unguentum, is characterized in that it is made up of the raw material of following weight: Radix Astragali 5-20g, eupolyphaga adult 2-5, Flos Lonicerae 5-15g, Fructus Schisandrae Chinensis 3-8g, Rhizoma Polygoni Cuspidati 6-13g, Sanguis Draxonis 3-6g, Semen Litchi 8-15g, Caulis Fibraureae 4-9g, sulfanilamide argentum powder 5-13g, Oleum Sesami 1-3kg.
2. the preparation method of diabetic foot infection promoting healing unguentum as claimed in claim 1, is characterized in that carrying out according to the following steps:
(1) dried is carried out to eupolyphaga adult, make its thorough mummification;
(2) said medicine is all ground to except Oleum Sesami the powder particle of 0.2-0.5mm;
(3) Oleum Sesami is heated to fluidized state, continues 15 minutes;
(4) in the Oleum Sesami of fluidized state, add the powder of the medicines such as the Radix Astragali, eupolyphaga adult, Flos Lonicerae, Fructus Schisandrae Chinensis, Rhizoma Polygoni Cuspidati, Sanguis Draxonis, Semen Litchi, Caulis Fibraureae respectively;
(5) stop heating Oleum Sesami, and wait for that Oleum Sesami is down to room temperature 20 DEG C;
(6) in cooled Oleum Sesami, sulfanilamide argentum powder is added;
(7) Oleum Sesami is reheated, make Oleum Sesami temperature reach 40-60 DEG C, and continue 3-5 minute;
(8) Oleum Sesami is cooled, be cooled to temperature 25 DEG C-38 DEG C;
(9) keep 25 DEG C-38 DEG C, leave standstill 48-72 hour;
(10) dispel unnecessary Oleum Sesami, only retain the mixture of medicine and Oleum Sesami;
(11) medicine and Oleum Sesami mixture are loaded stand-by according to the standard sub-bottle of every 50-60g.
3. the preparation method of diabetic foot infection promoting healing unguentum as claimed in claim 2, during use, is heated to 10 DEG C-18 DEG C by the Oleum Sesami in bottle and medicament mixed body, then smears to foot affected part.
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| CN201510730724.6A CN105327058A (en) | 2015-11-02 | 2015-11-02 | Anti-infection heal-promoting ointment for diabetic feet and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102861287A (en) * | 2012-08-28 | 2013-01-09 | 杨高林 | Chinese medicinal composition for treating damp-heat invasion blood stasis diabetic foot and preparation method thereof |
| CN102872335A (en) * | 2012-08-31 | 2013-01-16 | 杨高林 | Externally used Chinese medicine preparation for curing diabetic foot and preparation method thereof |
| CN102940749A (en) * | 2012-10-16 | 2013-02-27 | 王厚玲 | Traditional Chinese medicine paste for treatment of diabetic foot |
| CN102949555A (en) * | 2012-11-12 | 2013-03-06 | 姜婷婷 | Medicine for treating diabetic feet |
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2015
- 2015-11-02 CN CN201510730724.6A patent/CN105327058A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102861287A (en) * | 2012-08-28 | 2013-01-09 | 杨高林 | Chinese medicinal composition for treating damp-heat invasion blood stasis diabetic foot and preparation method thereof |
| CN102872335A (en) * | 2012-08-31 | 2013-01-16 | 杨高林 | Externally used Chinese medicine preparation for curing diabetic foot and preparation method thereof |
| CN102940749A (en) * | 2012-10-16 | 2013-02-27 | 王厚玲 | Traditional Chinese medicine paste for treatment of diabetic foot |
| CN102949555A (en) * | 2012-11-12 | 2013-03-06 | 姜婷婷 | Medicine for treating diabetic feet |
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Application publication date: 20160217 |
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