CN105326692A - Anti-radiation moisturizing sun screen and preparation method thereof - Google Patents
Anti-radiation moisturizing sun screen and preparation method thereof Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
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Abstract
The invention belongs to the technical field of cosmetics, and particularly relates to anti-radiation moisturizing sun screen. The sun screen is prepared from, by weight, water, butanediol, trehalose, allantoin, dimethyl acrylamide taurine ammonium/VP copolymer, polydimethylsiloxane, isononyl isononanoate, tridecyl stearate, cetearyl alcohol (and) cetearyl glucoside, glyceryl stearate (and) PEG-100 stearate, mica, zinc oxide, barium sulfate, oat beta-glucan, aloe extract, phenoxyethanol and methylparaben. The anti-radiation moisturizing sun screen effectively isolates electromagnetic radiation, keeps skin moist and clear, and is capable of fitting skin, safe and free of stimuli.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to a kind of radioprotective moisturizing sun screen and preparation method thereof.
Background technology
In daily life, computer, mobile phone, microwave, Wi-Fi ... be seen everywhere.Nowadays, everyone places oneself in the midst of among the immanent encirclement of electromagnetic wave for we, can say, we live in such one to have everywhere in the environment of radiation.Research shows: electromagenetic wave radiation to the langerhans' cells in skin and hypodermal cell inhibited, cause the change of skin corium cell function, very large to skin lesion, and belong to the injury of accumulation property, can cause that skin is dark and gloomy, aging, even canceration.As skin Long contact time computer, mobile phone, microwave oven etc., langerhans' cells quantity can greatly reduce, and hypodermal cell activity reduces, and weakens the defence immunocompetence of skin.
Electromagnetic radiation is classified as the fourth-largest environomental pollution source after water source, air, noise by World Health Organization (WHO), becomes the stealth " killer " of harm humans health.In the Chinese residents common skin diseases reason sequences in 2005 that health ministry is issued, electromagnetic radiation occupies first place in urbanite, in the data that World Health Organization (WHO) announces, because radiation-induced skin cancer accounts for 1/4th in global skin carcinoma patient numbers.
Sun screen on market is usually to isolate ultraviolet, color make-up, bright color for main purpose, and for the long-time crowd in the face of the product such as computer, mobile phone, effect of isolating electromagnetic radiation aspect is not enough, therefore needs a kind of effective radiation-resistant sun screen of research and development.
The leaf epidermis of plant is positioned at the outside of epidermis cell, is made up of the horny layer deposited and waxiness.Horny layer essence is network structure, and in forming process, constantly have waxiness to fill therebetween, these wax layers be filled in horny layer network structure are called as interior wax coat; Forming again the structure only having wax component outward at horny layer, is outer wax coat.Outer wax coat generally can form the waxiness crystal of self assembly.With sem observation, waxiness crystalline mi morphosis is multiformity.Plant classification scholar often claims this to have the wax Rotating fields of specific microcosmic conformation to be wax quilt.Leaf Epidermis wax component is complicated, is usually considered to the mixture of a type organic matter.By means of gas chromatography-mass spectrum, research worker finds that main composition is the fatty acid of long-chain, alcohol, aldehyde, ester and n ~ alkane, also have in certain plants epicutile wax other as cyclic terpene, phenols, the sterin even composition such as carotenoid.
About the research of Leaf Epidermis waxiness radiation-resisting functional, the product waxiness defect mutant of Semen Maydis such as Long have studied the radiation resistance of leaves of plants table wax layer, result shows: compared with normal plant, the angles of corn plant leaves lacking wax is subject to ultraviolet injury from shape to hereditary material and all enlarges markedly, and the leaf table waxiness also demonstrating extraction can absorb a large amount of ultraviolet; The leaf that the leaf that waxiness is many is fewer than waxiness can absorb more ultraviolet.The result of study to various plants such as Semen Pisi sativis such as Robberecht shows: leaf table waxiness all has barrier action to ultraviolet radiation, only has the ultraviolet less than 1% to enter mesophyll by leaf epidermis waxiness.Holmes and Keiller finds that the wax layer of leaf table is higher than the epidermal hair reflection efficiency of leaf epidermis, and energy is uv reflectance (330nm) and photosynthesis absorbing light (680nm) simultaneously, after removing waxiness, leaf epidermis all have dropped these two kinds of light reflectance, wherein larger to the degree of ultraviolet reflection rate decline.Visible, Leaf Epidermis waxiness has good radioprotective, but through retrieval, rarely seen Leaf Epidermis waxiness, the especially application of Folium Artemisiae Argyi waxiness in cosmetics.
Summary of the invention
In order to overcome the deficiencies in the prior art, the object of the present invention is to provide a kind of radioprotective moisturizing sun screen, it effectively isolates electromagnetic radiation, skin-moisturizing, skin, and thoroughly pastes skin clearly, safe and non-stimulating.
To achieve these goals, technical scheme of the present invention is as follows:
A kind of radioprotective moisturizing sun screen, comprise the component of following weight percent meter: water 45 ~ 80%, butanediol 2 ~ 8%, trehalose 1 ~ 4%, allantoin 0.05 ~ 0.5%, acrylamide dimethyltaurine ammonium/VP copolymer 0.2 ~ 2%, polydimethylsiloxane 1 ~ 5%, different n-nonanoic acid isononyl alcohol ester 2 ~ 6%, tridecyl alcohol stearate 1 ~ 5%, cetearyl alcohol (with) cetearyl glucoside 0.5 ~ 3%, glyceryl stearate (with) PEG-100 stearate 1 ~ 5%, Muscovitum 0.05 ~ 0.5%, zinc oxide 1 ~ 5%, barium sulfate 0.5 ~ 3%, avenabeta glucosan 1 ~ 5%, Aloe extraction solution 1 ~ 5%, phenoxyethanol 0.1 ~ 0.2% and methyl hydroxybenzoate 0.1 ~ 0.3%.
In order to strengthen the radioprotective effect of sun screen of the present invention further, described radioprotective moisturizing sun screen also comprises Folium Artemisiae Argyi waxiness 2 ~ 5% and Oleum Folium Artemisiae Argyi 1 ~ 5%.
As the preferred embodiment of the present invention, described radioprotective moisturizing sun screen is made up of the component of following weight percent meter: Folium Artemisiae Argyi waxiness 4%, Oleum Folium Artemisiae Argyi 3%, water 66.25%, butanediol 5%, trehalose 1%, allantoin 0.15%, acrylamide dimethyltaurine ammonium/VP copolymer 0.2%, polydimethylsiloxane 4%, different n-nonanoic acid isononyl alcohol ester 3%, tridecyl alcohol stearate 2%, cetearyl alcohol (with) cetearyl glucoside 1.5%, glyceryl stearate (with) PEG-100 stearate 1%, Muscovitum 0.1%, zinc oxide 3%, barium sulfate 1.5%, avenabeta glucosan 2%, Aloe extraction solution 2%, phenoxyethanol 0.1% and methyl hydroxybenzoate 0.1%.
Folium Artemisiae Argyi waxiness of the present invention and Oleum Folium Artemisiae Argyi are obtained by following methods: first get fresh Folium Artemisiae Argyi, fill post after pulverizing; Then with the medical material post that cyclohexane extraction recycling elution installs, after having liquid out, survey the flow velocity of lower effluent, after recycling elution 5BV, tail connects a silicagel column absorption use, after continuing recycling elution 3BV, pulls down medical material post, to fan the air the cyclohexane extraction in medical material post with air pump, the cyclohexane extraction got is loaded in silicagel column and adsorbs; Last waxiness of separately getting in cyclohexane extraction flushing silicagel column, after the wash water color eluted shoals, the cyclohexane extraction fanned the air with air pump in post, merges with eluent, obtains Folium Artemisiae Argyi waxiness after reclaiming cyclohexane extraction with Rotary Evaporators; With 20% Ethyl acetate-cyclohexane eluting silica gel post, after eluting 3BV, after the Ethyl acetate-cyclohexane fanned the air with air pump in post, after reclaiming Ethyl acetate-cyclohexane with Rotary Evaporators, obtain Oleum Folium Artemisiae Argyi extractum; Join in molecular distillation apparatus by Oleum Folium Artemisiae Argyi extractum, separated obtains Oleum Folium Artemisiae Argyi.
Present invention also offers the preparation method of above-mentioned radioprotective moisturizing sun screen, comprise the following steps:
S1, Jiang Shui, butanediol, trehalose, allantoin and acrylamide dimethyltaurine ammonium/VP copolymer add in emulsifying pot, are heated to 75 ~ 80 DEG C and are stirred to and dissolve completely, obtain material A;
S2, by polydimethylsiloxane, different n-nonanoic acid isononyl alcohol ester, tridecyl alcohol stearate, cetearyl alcohol (with) cetearyl glucoside, glyceryl stearate (with) PEG-100 stearate, Muscovitum, zinc oxide and barium sulfate adds in oil cauldron, be heated to 75 ~ 80 DEG C to be stirred to and to dissolve completely, obtain material B;
S3, to be pumped in described material A by described material B, to stir, open homogenizing, constant temperature stirs, cooling;
S4, be cooled to 40 DEG C, add avenabeta glucosan, Aloe extraction solution, phenoxyethanol and methyl hydroxybenzoate, stir, cool and obtain radioprotective moisturizing sun screen.
Further, adding of Folium Artemisiae Argyi waxiness and Oleum Folium Artemisiae Argyi is also comprised in described step S2.
Folium Artemisiae Argyi waxiness of the present invention can effective radioprotective as a Leaf Epidermis waxiness, also has the effect of skin moistening, antibacterial, skin of releiving simultaneously; Described barium sulfate is used as barium meal in medical science, can effectively pass by block radiation line; Described zinc oxide is a kind of wide spectrum screener, has electrostatic screen and antistatic property; Described avenabeta glucosan not only has anti-sunlight function and can reduce pain inflammation, can also promote that langerhans' cells is bred, can strengthen the immunocompetence of skin.Described Folium Artemisiae Argyi waxiness, barium sulfate, zinc oxide and avenabeta glucosan combine collaborative, the electromagnetic radiation such as effective anti-radio wave, microwave, visible ray, ultraviolet, then in conjunction with the natural extract such as Oleum Folium Artemisiae Argyi, Aloe extraction solution, potent skin-moisturizing, skin; Coordinate the substrate of the compositions such as butanediol, trehalose, allantoin and acrylamide dimethyltaurine ammonium/VP copolymer again, obtaining radioprotective moisturizing sun screen of the present invention had both effectively isolated electromagnetic radiation, skin-moisturizing, skin, and thoroughly pasted skin clearly, safe and non-stimulating simultaneously.
Therefore, compared with prior art, advantage of the present invention is:
(1) radioprotective moisturizing sun screen of the present invention has good radiation resistance, the electromagnetic radiation such as ultraviolet, visible ray, radio wave, microwave can be isolated, thus reduce the radiation damage suffered by skin, reduce the radiation damage degree of skin, and stable system, safety is high.
(2) radioprotective moisturizing sun screen safety of the present invention, nonirritant, stay in grade, it contains the natural materials such as Folium Artemisiae Argyi waxiness, Oleum Folium Artemisiae Argyi, avenabeta glucosan, Aloe extraction solution, clearly pastes skin, effective radioprotective, potent moisturizing simultaneously, skin moistening;
(3) raw material of radioprotective moisturizing sun screen of the present invention is easy to get, and cost of manufacture is low, and preparation method is simple and easy simultaneously, and process stabilizing, has good application prospect.
Detailed description of the invention
Further describe the present invention below by way of detailed description of the invention, but the present invention is not limited only to following examples.Within the scope of the invention or not departing from content of the present invention, spirit and scope, radioprotective moisturizing sun screen of the present invention is suitably improved, replaces the identical component of effect, will become apparent to those skilled in the art that they are all deemed to be included within scope of the present invention.
In the embodiment of the present invention producer of part material and article No. as follows:
The formula of the embodiment of the present invention 1 ~ 4 radioprotective moisturizing sun screen is as follows:
Wherein, described Folium Artemisiae Argyi waxiness and Oleum Folium Artemisiae Argyi are obtained by following methods: first get fresh Folium Artemisiae Argyi, load in a 30L steel column by the Folium Artemisiae Argyi after pulverizing; Then with the medical material post that cyclohexane extraction recycling elution installs, after having liquid out, survey the flow velocity of lower effluent, after recycling elution 5BV, tail connects the silicagel column absorption use of a 20L, after continuing recycling elution 3BV, pulls down medical material post, to fan the air the cyclohexane extraction in medical material post with air pump, the cyclohexane extraction got is loaded in silicagel column and adsorbs; Last waxiness of separately getting in cyclohexane extraction flushing silicagel column, after the wash water color eluted shoals, the cyclohexane extraction fanned the air with air pump in post, merges with eluent, obtains Folium Artemisiae Argyi waxiness after reclaiming cyclohexane extraction with Rotary Evaporators; With 20% Ethyl acetate-cyclohexane eluting silica gel post, after eluting 3BV, after the Ethyl acetate-cyclohexane fanned the air with air pump in post, after reclaiming Ethyl acetate-cyclohexane with Rotary Evaporators, obtain Oleum Folium Artemisiae Argyi extractum; Join in molecular distillation apparatus by Oleum Folium Artemisiae Argyi extractum, separated obtains Oleum Folium Artemisiae Argyi.
The preparation method of the embodiment of the present invention 1 ~ 4 radioprotective moisturizing sun screen is as follows:
S1, Jiang Shui, butanediol, trehalose, allantoin and acrylamide dimethyltaurine ammonium/VP copolymer add in emulsifying pot, are heated to 75 DEG C and are stirred to and dissolve completely, obtain material A;
S2, by polydimethylsiloxane, different n-nonanoic acid isononyl alcohol ester, tridecyl alcohol stearate, cetearyl alcohol (with) cetearyl glucoside, glyceryl stearate (with) PEG-100 stearate, Muscovitum, zinc oxide and barium sulfate adds in oil cauldron, be heated to 75 DEG C to be stirred to and to dissolve completely, obtain material B;
S3, to be pumped in described material A by described material B, to stir, open homogenizing, constant temperature stirs, cooling;
S4, be cooled to 40 DEG C, add avenabeta glucosan, Aloe extraction solution, phenoxyethanol and methyl hydroxybenzoate, stir, cool and obtain radioprotective moisturizing sun screen.
Adding of Folium Artemisiae Argyi waxiness and Oleum Folium Artemisiae Argyi is also comprised in described step S2.
Meet the pertinent regulations requirement of QB/T1857-2013 through the inspection embodiment of the present invention 1 ~ 4 product, sense index (color and luster, fragrance, structure) meets industry regulation, and physical and chemical index (PH, heat-resisting, cold-resistant, active matter) and sanitary index meet industry regulation.
The formula of comparative example one, two sun screen is as follows:
The preparation method of the Folium Artemisiae Argyi waxiness of comparative example one, two and the preparation method reference embodiment of the present invention radioprotective moisturizing sun screen of sun screen.
Comparative example three
Formula of this comparative example sun screen and preparation method thereof is with embodiment 3.As different from Example 3: when preparing Folium Artemisiae Argyi waxiness and Oleum Folium Artemisiae Argyi, use ethanol to replace cyclohexane extraction, 20% Ethyl acetate-cyclohexane is replaced by 20% ethyl acetate-ethanol.
test example one, radioprotective moisturizing sun screen ultraviolet injury resistant of the present invention zoopery
The mechanism of radiation damage is: effects of ionizing radiation is in organism biomembrane, enzyme, nucleic acid etc., cause the injury response of a series of free radical, lipid peroxide is the main after irradiation radioactivity poisonous substance of body, when after irradiating, body not yet finds any damage, it just produces, therefore, it is the product after radiation, can increase the weight of radiation damage again.The protection system mainly enzyme scavenger of body defenses free radical lipid peroxidation injury: comprise SOD, catalase (CAT) etc., the antioxidase in body is the defying age material of " endogenous ".Antioxidant defense enzyme (as SOD) activity reduces can make Skin Cell present aging state, and senile cell slows down due to metabolism, poor to the repair function of damage, more easily causes photic damage, acceleration skin aging.Malonaldehyde (MDA) is hurt due to organ senescence or under adverse environmental factor, and its tissue or organ membrane lipid generation peroxidization produce, and its content injures substantial connection with old and feeble and adverse circumstance.UV radiation produces a large amount of ROS, beyond the normal defense ability of body, it while antioxidase SOD and CAT, attacks the polyunsaturated fatty acid in phosphide on biomembrane film in consumption skin, cause membrane lipid peroxidatio chain reaction, finally cause MDA content to increase.Ultraviolet radiation can bring out membrane lipid peroxidatio reaction, causes the damage of biomembrane and DNA.Therefore, the height of SOD content and MDA content in skin, determines the size of skin injury degree.
One, materials and methods
1, animal: SD healthy rat 18, body weight 150 ± 30g, male and female half and half; Rat is in testing prospective adaptation environment one week, raising temperature 22-25 DEG C.
2, medicine: according to the embodiment of the present invention 1,3, the sun screen that the raw material of comparative example one, three and method are made.
3, animal grouping: be divided into 6 groups at random after rat back depilation, often organize 3:
Blank group: back is left intact, normally feeds;
Radiation patterns group: back is left intact, carries out radiation;
Sun screen 1 group: the sun screen 2.0gkg of embodiment 1 is smeared at back
-1, carry out radiation;
Sun screen 2 groups: the sun screen 2.0gkg of embodiment 3 is smeared at back
-1, carry out radiation;
Sun screen 3 groups: the sun screen 2.0gkg of comparative example one is smeared at back
-1, carry out radiation;
Sun screen 4 groups: the sun screen 2.0gkg of comparative example three is smeared at back
-1, carry out radiation;
Two, experimental procedure:
1, rat ultraviolet (UV) beta radiation: be fixed on by rat on special plank, with lead shielding, only expose the back after process, irradiate with UVB therapeutic instrument, dosage is 48mJ/cm
2.Irradiate after 2 days, put to death rat, observe indices.
2, the SOD content of each group rat skin sample: the quality weighing each group of rat skin sample, adds the normal saline of pre-cooling, with glass homogenizer grinding and frozen centrifugation, is prepared into 10%(V/V) tissue homogenate.Measure test kit with the superoxide dismutase (SOD) purchased from Suo Laibao bio tech ltd, Shanghai and measure the SOD content in rat skin sample according to the requirement of test kit description.Measure test kit with the malonaldehyde (MDA) purchased from abundant Bioisystech Co., Ltd of upper Hisense and measure the MDA content in rat skin sample according to the requirement of test kit description.
3, rat skin Observation On The Morphology: the skin samples of each group of rat is placed in formalin and fixes 48 hours, ethanol dewaters step by step, carries out ultrathin section and HE dyeing after paraffin embedding.
Three, experimental result:
1, SOD and MDA content in each group rat skin, the results are shown in following table 1.
Table 1 respectively organizes SOD and MDA content in rat skin
Compare with blank group, ##P < 0.01; Compare with radiation patterns group, * P < 0.05, * * P < 0.01.
From upper table 1:
(1) model group rats is after partial radiation, and the SOD content in skin is compared with normal group, reduces certain level, has significant difference (P < 0.01); And sun screen group rat is after partial radiation, SOD content in skin is compared with model group, have significant difference (P < 0.05 or P < 0.01), all can suppress the reduction of SOD content, wherein the inhibition of sun screen 2 groups is the most obvious;
(2) model group rats is after partial radiation, and the MDA content in skin is compared with normal group, increases certain level, has significant difference (P < 0.01); And sun screen group rat is after partial radiation, MDA content in skin is compared with model group, have significant difference (P < 0.05 or P < 0.01), all can suppress the rising of MDA content, wherein the inhibition of sun screen 2 groups is the most obvious.
2, rat skin Observation On The Morphology result:
(1) blank group rat skin structural integrity, epidermis and corium boundary line clear, epidermis is more regular, and skin corium is thicker, and dyeing is comparatively even, and the cell number of plies is more;
(2) radiation patterns group rat skin structure disturbance, is hard to tell epidermis and corium boundary line, dyes uneven and dyes more shallow;
(3) sun screen 1,3,4 groups of rat skin structural rate model group rats skin textures are complete, and epidermis and corium boundary line still can be seen, though epidermis unrest, skin corium is more regular, dye more even;
(4) sun screen 3 groups of rat skin structures are obviously complete than model group rats skin texture, and epidermis and corium boundary line can be seen, epidermis is compared with the rule of sun screen 1,3,4 groups, and skin corium is more regular, dyes more even.
Above-mentioned testing result illustrates that radioprotective moisturizing sun screen of the present invention can reduce the radiation damage degree of rat skin, thus prove that radioprotective moisturizing sun screen of the present invention can reduce the radiation damage suffered by rat skin, and safety is high, the radioprotective effect of the sun screen wherein containing the described Folium Artemisiae Argyi waxiness that obtained by cyclohexane extraction eluting and Oleum Folium Artemisiae Argyi is better, has powerful radiation resistance to skin.
the result of use of test example two, radioprotective moisturizing sun screen of the present invention
One, trial target: the sun screen that embodiment 2 ~ 4, comparative example two prepare
Two, tested crowd
Sex number: female, 120 people
Age: between 25 ~ 50 years old
Health status: subjects skin is healthy, without dermatosis allergies, meets experimenter and volunteers inclusion criteria.
Grouping: be divided into 4 groups, often organize 30 people, often organizes 29 ± 2 years old mean age.
Three, method of testing: the said goods on probation, uses two weeks continuously, observe and experience result of use.
Four, testing evaluation result is as follows:
The feedback conclusive table on probation of table 2 embodiment 2 radioprotective moisturizing sun screen
The feedback conclusive table on probation of table 3 embodiment 3 radioprotective moisturizing sun screen
The feedback conclusive table on probation of table 4 embodiment 4 radioprotective moisturizing sun screen
The feedback conclusive table on probation of table 5 comparative example two sun screen
From above-mentioned test result:
(1) show according to the feedback on probation of experimenter, radioprotective moisturizing sun screen of the present invention pastes skin clearly thoroughly, and glutinous not greasy after using, moisture retention is good, and skin is moistened, and isolation effect is good; People is not had to occur phenomena of cutaneous irritation in the questionnaire of simultaneously experimenter.The highest with the overall merit of embodiment 3 radioprotective moisturizing sun screen in embodiment 2 ~ 4 radioprotective moisturizing sun screen, therefore, embodiment 3 is the most preferred embodiment of radioprotective moisturizing sun screen of the present invention.
(2) sun screen of comparative example two is not containing Aloe extraction solution and Oleum Folium Artemisiae Argyi, and its pro-skin and moistening effect, not as good as embodiment 2 ~ 4, illustrate that each component of the present invention is worked in coordination with.
Above-described embodiment is the present invention's preferably embodiment; but embodiments of the present invention are not restricted to the described embodiments; change, the modification done under other any does not deviate from spirit of the present invention and principle, substitute, combine, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.
Claims (6)
1. a radioprotective moisturizing sun screen, it is characterized in that, comprise the component of following weight percent meter: water 45 ~ 80%, butanediol 2 ~ 8%, trehalose 1 ~ 4%, allantoin 0.05 ~ 0.5%, acrylamide dimethyltaurine ammonium/VP copolymer 0.2 ~ 2%, polydimethylsiloxane 1 ~ 5%, different n-nonanoic acid isononyl alcohol ester 2 ~ 6%, tridecyl alcohol stearate 1 ~ 5%, cetearyl alcohol (with) cetearyl glucoside 0.5 ~ 3%, glyceryl stearate (with) PEG-100 stearate 1 ~ 5%, Muscovitum 0.05 ~ 0.5%, zinc oxide 1 ~ 5%, barium sulfate 0.5 ~ 3%, avenabeta glucosan 1 ~ 5%, Aloe extraction solution 1 ~ 5%, phenoxyethanol 0.1 ~ 0.2% and methyl hydroxybenzoate 0.1 ~ 0.3%.
2. radioprotective moisturizing sun screen as claimed in claim 1, it is characterized in that, described radioprotective moisturizing sun screen also comprises Folium Artemisiae Argyi waxiness 2 ~ 5% and Oleum Folium Artemisiae Argyi 1 ~ 5%.
3. radioprotective moisturizing sun screen as claimed in claim 2, it is characterized in that, described radioprotective moisturizing sun screen is made up of the component of following weight percent meter: Folium Artemisiae Argyi waxiness 4%, Oleum Folium Artemisiae Argyi 3%, water 66.25%, butanediol 5%, trehalose 1%, allantoin 0.15%, acrylamide dimethyltaurine ammonium/VP copolymer 0.2%, polydimethylsiloxane 4%, different n-nonanoic acid isononyl alcohol ester 3%, tridecyl alcohol stearate 2%, cetearyl alcohol (with) cetearyl glucoside 1.5%, glyceryl stearate (with) PEG-100 stearate 1%, Muscovitum 0.1%, zinc oxide 3%, barium sulfate 1.5%, avenabeta glucosan 2%, Aloe extraction solution 2%, phenoxyethanol 0.1% and methyl hydroxybenzoate 0.1%.
4. radioprotective moisturizing sun screen as claimed in claim 2, it is characterized in that, described Folium Artemisiae Argyi waxiness and Oleum Folium Artemisiae Argyi are obtained by following methods: first get fresh Folium Artemisiae Argyi, fill post after pulverizing; Then with the medical material post that cyclohexane extraction recycling elution installs, after having liquid out, survey the flow velocity of lower effluent, after recycling elution 5BV, tail connects a silicagel column absorption use, after continuing recycling elution 3BV, pulls down medical material post, to fan the air the cyclohexane extraction in medical material post with air pump, the cyclohexane extraction got is loaded in silicagel column and adsorbs; Last waxiness of separately getting in cyclohexane extraction flushing silicagel column, after the wash water color eluted shoals, the cyclohexane extraction fanned the air with air pump in post, merges with eluent, obtains Folium Artemisiae Argyi waxiness after reclaiming cyclohexane extraction with Rotary Evaporators; With 20% Ethyl acetate-cyclohexane eluting silica gel post, after eluting 3BV, after the Ethyl acetate-cyclohexane fanned the air with air pump in post, after reclaiming Ethyl acetate-cyclohexane with Rotary Evaporators, obtain Oleum Folium Artemisiae Argyi extractum; Join in molecular distillation apparatus by Oleum Folium Artemisiae Argyi extractum, separated obtains Oleum Folium Artemisiae Argyi.
5. prepare a method for radioprotective moisturizing sun screen as claimed in claim 1, it is characterized in that, comprise the following steps:
S1, Jiang Shui, butanediol, trehalose, allantoin and acrylamide dimethyltaurine ammonium/VP copolymer add in emulsifying pot, are heated to 75 ~ 80 DEG C and are stirred to and dissolve completely, obtain material A;
S2, by polydimethylsiloxane, different n-nonanoic acid isononyl alcohol ester, tridecyl alcohol stearate, cetearyl alcohol (with) cetearyl glucoside, glyceryl stearate (with) PEG-100 stearate, Muscovitum, zinc oxide and barium sulfate adds in oil cauldron, be heated to 75 ~ 80 DEG C to be stirred to and to dissolve completely, obtain material B;
S3, to be pumped in described material A by described material B, to stir, open homogenizing, constant temperature stirs, cooling;
S4, be cooled to 40 DEG C, add avenabeta glucosan, Aloe extraction solution, phenoxyethanol and methyl hydroxybenzoate, stir, cool and obtain radioprotective moisturizing sun screen.
6. as claimed in claim 5 the preparation method of radioprotective moisturizing sun screen, it is characterized in that, in described step S2, also comprise adding of Folium Artemisiae Argyi waxiness and Oleum Folium Artemisiae Argyi.
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| CN105769669A (en) * | 2016-03-22 | 2016-07-20 | 李晨露 | Skin care product capable of increasing electromagnetic radiation resistance of skin |
| CN105997821A (en) * | 2016-07-11 | 2016-10-12 | 滁州格锐矿业有限责任公司 | Preparing method of cosmetic containing sericite powder |
| CN106727215A (en) * | 2016-11-26 | 2017-05-31 | 无锡市汉方八珍科技有限公司 | A kind of moisturizing, moist sun screen |
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| US20040191189A1 (en) * | 2000-04-05 | 2004-09-30 | Jean-Christophe Choulot | Sunscreen milk |
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| CN102488627A (en) * | 2011-12-31 | 2012-06-13 | 上海宝姿化妆品有限公司 | Radiation-resistant and moisture-retention make-up base, lotion and water |
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| CN105769669A (en) * | 2016-03-22 | 2016-07-20 | 李晨露 | Skin care product capable of increasing electromagnetic radiation resistance of skin |
| CN105997821A (en) * | 2016-07-11 | 2016-10-12 | 滁州格锐矿业有限责任公司 | Preparing method of cosmetic containing sericite powder |
| CN106727215A (en) * | 2016-11-26 | 2017-05-31 | 无锡市汉方八珍科技有限公司 | A kind of moisturizing, moist sun screen |
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| CN105326692B (en) | 2018-06-19 |
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