CN105309825A - Feed additive capable of resisting heat stress and relieving oxidative stress injuries and used for broiler chickens - Google Patents
Feed additive capable of resisting heat stress and relieving oxidative stress injuries and used for broiler chickens Download PDFInfo
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- CN105309825A CN105309825A CN201510858190.5A CN201510858190A CN105309825A CN 105309825 A CN105309825 A CN 105309825A CN 201510858190 A CN201510858190 A CN 201510858190A CN 105309825 A CN105309825 A CN 105309825A
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Abstract
The invention discloses a feed additive capable of resisting heat stress and relieving oxidative stress injuries and used for broiler chickens. The feed additive is prepared from the following raw materials in parts by mass: 20-30 parts of compound Chinese herbal medicine extract, 15-20 parts of a yeast culture, 5-10 parts of alpha-ketoglutaric acid, 5-10 parts of glycine betaine, 2-4 parts of sodium hydrogen carbonate, 4-8 parts of ammonium chloride, 3-5 parts of magnesium sulfate and 2-3 parts of chromium picolinate, wherein the compound Chinese herbal medicines comprise garden burnet roots, dandelions, indigowoad roots, spina date seeds, Chinese fevervine herb, herb of shorthorned epimedium, astragalus membranaceus, Chinese angelica, common andrographis herb and liquorice roots. With the adoption of a scientific proportion of a plurality of raw materials with different types, the '1+1>2' synergistic effect is realized; the product has a remarkable effect, the heat stress resisting capability of the broiler chickens under a high-temperature condition can be remarkably improved and the oxidative stress injuries can be relieved; the nutrition digestion rate is improved, the growth is promoted and the feed/gain ratio is reduced; and the feed additive is safe and convenient to use, does not have the problems of drug residues, drug resistance and the like, and has a wide market prospect.
Description
Technical field
The present invention relates to a kind of feed additive for chickens and preparation method thereof, the feed additive for chickens of a kind of anti-heat stress, alleviation oxidativestress damage, belongs to feed additive field specifically.
Background technology
In recent years, in Production of Livestock and Poultry practice, people are in order to pursue higher economic benefit, and many plants generally adopt intensive farm mode, make temperature more and more become the essential environmental factors causing Animal stress.Heat stress refers to the summation of the non-specific physiologic response reaction that body is made due to the high temperature stimulation of external environment.Heat stress can make the decline of poultry production efficiency, efficiency of feed utilization reduction, the incidence of disease and the death rate raise, and brings about great losses to poultry production.
Broiler chicken due to feather abundant, fever, metabolism is vigorous, and skin does not have sweat gland, and under hot conditions, with the waste heat produced in respiratory tract evaporative heat loss releaser to maintain body thermal balance, therefore heat stress is extremely remarkable on its impact.The impact of heat stress on broiler chicken digestibility be mainly manifested in weaken gastral wriggling, food and extend holdup time, reduce alimentary canal endoenzyme activity, change gastral haemodynamics, to destroy in alimentary canal micro-ecological environment etc.Heat stress on the impact of broiler chicken feed intake mainly through acting on hypothalamic feeding center, reduce its excitability, the simultaneously orthosympathetic excitement of alimentary canal makes alimentary canal activity weaken, and causes alimentary canal food to fill, thus compressing alimentary canal mechanoceptor and reach the effect of appetite-suppressing.Research finds, the ambient temperature range of suitable poultry production is 21 ~ 26 DEG C.When environment temperature is higher than heat rating such as grade, often raise 1 DEG C, feed consumption rate reduces 1.4% ~ 1.6%.When ambient temperature is more than 32 DEG C, poultry physiological dysfunction, production performance declines to a great extent, and even occurs heat shock and death.The broiler chicken of raising under thermal environment, average daily gain and food consumption are all remarkable in raising the broiler chicken in preferred ambient temperature.
The negative effect that current domestic and international many scholars bring to alleviate or eliminate heat stress, has done large quantifier elimination in the impact of development and application heat stress fighting additive on meat chicken production performance, but has mostly used single additive.Because the mechanism of current generation heat stress is many-sided, the effect of single heat stress fighting additive is limited, be difficult to the impact eliminated completely or farthest or alleviation heat stress brings, domestic and international many research workers have taken to the research of compound additive, and comprehensive various heat stress fighting additive makes it to become a kind of compound additive is just becoming the emphasis studying application from now on.
Summary of the invention
The object of the invention is to according to above shortcomings in prior art, based on China's traditional medical theory, excavate Chinese herbal medicine and there is the double action treating sick health care, draw its essential part, selected clearing heat and detoxicating, calm the nerves take care of health, vital energy regualting and blood circulation-promoting, help astringent or styptic treatment for spontaneous sweating wait Chinese medicine, exploitation one can effectively anti-heat stress, alleviation oxidativestress damage, improve nutrition digestion absorptivity, promote efficient, the green meat-chicken feedstuff additive product of growth of meat chicken, reach the object of efficient cultivation.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
A feed addictive for broiler chicken anti-heat stress, alleviation oxidativestress damage, is characterized in that being made up of following mass fraction raw material: composite Chinese herbal extract 20 ~ 30 parts, yeast culture 15 ~ 20 parts, KG 5 ~ 10 parts, betaine 5 ~ 10 parts, sodium acid carbonate 2 ~ 4 parts, ammonium chloride 4 ~ 8 parts, 3 ~ 5 parts, magnesium sulfate, chromium picolinate 2 ~ 3 parts.
Described composite Chinese herbal extract is the mixture of herbal raw material in alcohol extracting and water extraction after garden burnet 20 ~ 30 parts, dandelion 20 ~ 30 parts, Radix Isatidis 15 ~ 20 parts, spina date seed 10 ~ 15 parts, Chinese Fevervine Herb 10 ~ 15 parts, HERBA EPIMEDII 8 ~ 12 parts, the Radix Astragali 8 ~ 10 parts, Radix Angelicae Sinensis 8 ~ 10 parts, Herba Andrographitis 3 ~ 5 parts, Radix Glycyrrhizae 2 ~ 3 parts of ratio mixing.
The preparation method of above-mentioned composite Chinese herbal extract specifically comprises: (1) Chinese herbal medicine mixes after pulverizing in proportion; (2) alcohol extracting: the absolute ethyl alcohol adding Chinese herbal medicine mass ratio 10 times, refluxing extraction 2 ~ 3h, filter, concentration and recovery ethanol, obtains ethanol extract; (3) water extraction: the pure water residue after alcohol extract being added 3 times of mass ratioes, reclaims water extraction 4 ~ 6h, filters, and concentrated, spraying dry obtains water extract; (4) mix: ethanol extract and water extract are mixed.
In above-mentioned raw materials: (1) Chinese herbal medicine comes from natural, tcm product safely, low medicine is residual, toxic and side effect is little, can be rated as " green " medicine, is the potential resource that China has international advantage.Have wide practical use as feed addictive.The Chinese herbal medicine selected has the effects such as clearing heat and detoxicating, anti-inflammation, makes an addition in feed, can strengthen the adaptability of chicken to high temperature, adjustment human body immune function, alleviates chicken heat shock reaction; (2) yeast culture is a kind of pure natural feedstuff raw material, can improve feed palatability and digestibility.Good palatability can maintain stable feed intake; Good feed digestibility can make animal absorb more nutrition to promote production performance; Some nearest researchs show, yeast culture has stimulates cud CELLULOLYTIC BACTERIUM and lactic acid bacteria breeding, changes lumen fermentation mode, reduces cud ammonia density, improve the effect such as microbial nitrogen supply and feed digestibility; (3) betaine has as feed addictive provides methyl donor function, can save some methionine, have osmotic pressure in control agent, mitigation stress, promote fat metabolism and protein synthesis, improve the function of lean meat percentage, and the curative effect of anticoccidial drug can be strengthened; (4) add sodium acid carbonate in daily ration, weightening finish and the feed intake of broiler chicken under heat stress condition can be significantly improved, mainly due to NaHCO
3add the amount of drinking water of chicken; (5) during heat stress there is respiratory alkalosis in chicken, supplements NH in daily ration or drinking-water
4cl, obviously can reduce pH value of blood, alleviates its harm.(6) high temperature significantly reduces the content of chromium in kidney, adds chromium picolinate the deposition of chromium in liver is increased in daily ration, reduces plasma corticosterone levels, strengthens animal immunizing power, thus slows down the harm of heat stress to broiler chicken.
The invention provides a kind of broiler chicken anti-heat stress, alleviate the feed addictive of oxidativestress damage, it is characterized in that preparation technology is the mixing that proportions after being pulverized by above-mentioned raw materials, product is powdery, and fineness is 100-200 order.
The invention provides a kind of broiler chicken anti-heat stress, alleviate the feed addictive of oxidativestress damage, add in daily ration or drinking-water in 0.5 ~ 1% ratio during use, dorking heat-resistant stress ability can be improved, alleviate oxidativestress damage.
Compared with prior art, the present invention has following significant advantage: one is that Chinese herbal medicine nature and flavor are together different, effect also exists huge difference, complicated interaction relationship is there is after different Chinese herbal medicine combinations, and proportioning between Chinese herbal medicine is closer, different ratio also will make " monarch " relation that substantial change occurs, thus make the relation generation material alterations of composite Chinese herbal, the application's scientific matching garden burnet, dandelion, Radix Isatidis, spina date seed, Chinese Fevervine Herb, HERBA EPIMEDII, the Radix Astragali, Radix Angelicae Sinensis, Herba Andrographitis, Radix Glycyrrhizae, achieve unforeseeable technique effect, and alcohol dissolubility and the water-solubility function active material of Chinese herbal medicine is made full use of by alcohol extracting and water extraction, avoid the drawback that cannot absorb Chinese herbal medicine active functional component because broiler chicken alimentary canal is short, two is on the basis of Chinese herbal medicine anti-heat stress, compositely further the yeast extract, KG, betaine, sodium acid carbonate, ammonium chloride, magnesium sulfate, chromium picolinate etc. with remarkable growth promotion, anti-heat stress effect are proved to be, by the synergy between different component, improve the action effect of product of the present invention further, serve the effect of " 1+1>2 ", three is safe and convenient to use, there is not the problem such as medicament residue and drug resistance, has wide market prospects.
The invention provides a kind of broiler chicken anti-heat stress, alleviate the feed addictive of oxidativestress damage, result of the test shows, add 1% product of the present invention in daily ration after, under 26 ~ 30 DEG C of conditions, be bred as broiler chicken average daily gain amount and reach 94.32 ± 1.58g, improve 12.69% compared with the control group not adding product of the present invention in daily ration, feed-weight ratio comparatively control group reduces by 8.96%, and difference extremely significantly (P<0.01); Organ index (organ weight/broiler chicken live-weight) is measured after raising 42d, thymus index, index and spleen index, bursal index are all significantly higher than blank group and positive controls (adding 0.005% aureomycin in daily ration), and difference extremely significantly (P<0.01).Result of the test also shows growth promotion, anti-heat stress effect of changing products material composition or reduction product more remarkable in regular meeting, and difference extremely significantly (P<0.01).
Detailed description of the invention
Below by embodiment, the present invention will be further described.
embodiment 1:
A feed addictive for broiler chicken anti-heat stress, alleviation oxidativestress damage, concrete preparation process is as follows:
(1) herbal raw material mixing: the raw material after pulverizing is mixed in garden burnet 30 parts, dandelion 20 parts, Radix Isatidis 20 parts, spina date seed 10 parts, Chinese Fevervine Herb 15 parts, HERBA EPIMEDII 8 parts, the Radix Astragali 10 parts, Radix Angelicae Sinensis 8 parts, Herba Andrographitis 5 parts, Radix Glycyrrhizae 2 parts of ratios;
(2) alcohol extracting: the absolute ethyl alcohol adding Chinese herbal medicine mass ratio 10 times, refluxing extraction 2 ~ 3h, filter, concentration and recovery ethanol, obtains ethanol extract;
(3) water extraction: the pure water residue after alcohol extract being added 3 times of mass ratioes, reclaims water extraction 4 ~ 6h, filters, and concentrated, spraying dry obtains water extract;
(4) mix: ethanol extract and water extract are mixed;
(5) pulp furnish: according to Chinese herbal medicine extract 30 parts, yeast culture 15 parts, KG 10 parts, betaine 5 parts, sodium acid carbonate 4 parts, ammonium chloride 8 parts, 3 parts, magnesium sulfate, the accurate proportioning raw material of chromium picolinate 3 parts of ratios;
(6) pulverize: after being pulverized by above-mentioned raw materials, cross 100-200 mesh sieve;
(7) mix: the raw material after pulverizing is mixed, mixture homogeneity >=95%, obtain broiler chicken anti-heat stress, alleviate the feed addictive of oxidativestress damage.
embodiment 2:
A feed addictive for broiler chicken anti-heat stress, alleviation oxidativestress damage, concrete preparation process is as follows:
(1) herbal raw material mixing: the raw material after pulverizing is mixed in garden burnet 20 parts, dandelion 30 parts, Radix Isatidis 15 parts, spina date seed 15 parts, Chinese Fevervine Herb 10 parts, HERBA EPIMEDII 12 parts, the Radix Astragali 8 parts, Radix Angelicae Sinensis 10 parts, Herba Andrographitis 3 parts, Radix Glycyrrhizae 3 parts of ratios;
(2) alcohol extracting: the absolute ethyl alcohol adding Chinese herbal medicine mass ratio 10 times, refluxing extraction 2 ~ 3h, filter, concentration and recovery ethanol, obtains ethanol extract;
(3) water extraction: the pure water residue after alcohol extract being added 3 times of mass ratioes, reclaims water extraction 4 ~ 6h, filters, and concentrated, spraying dry obtains water extract;
(4) mix: ethanol extract and water extract are mixed;
(5) pulp furnish: according to Chinese herbal medicine extract 20 parts, yeast culture 20 parts, KG 5 parts, betaine 10 parts, sodium acid carbonate 2 parts, ammonium chloride 4 parts, 5 parts, magnesium sulfate, the accurate proportioning raw material of chromium picolinate 2 parts of ratios;
(6) pulverize: after being pulverized by above-mentioned raw materials, cross 100-200 mesh sieve;
(7) mix: raw material after pulverizing is mixed, mixture homogeneity >=95%, obtain broiler chicken anti-heat stress, alleviate the feed addictive of oxidativestress damage.
embodiment 3:
A feed addictive for broiler chicken anti-heat stress, alleviation oxidativestress damage, concrete preparation process is as follows:
(1) herbal raw material mixing: the raw material after pulverizing is mixed in garden burnet 25 parts, dandelion 25 parts, Radix Isatidis 18 parts, spina date seed 13 parts, Chinese Fevervine Herb 12 parts, HERBA EPIMEDII 10 parts, the Radix Astragali 9 parts, Radix Angelicae Sinensis 9 parts, Herba Andrographitis 4 parts, Radix Glycyrrhizae 2.5 parts of ratios;
(2) alcohol extracting: the absolute ethyl alcohol adding Chinese herbal medicine mass ratio 10 times, refluxing extraction 2 ~ 3h, filter, concentration and recovery ethanol, obtains ethanol extract;
(3) water extraction: the pure water residue after alcohol extract being added 3 times of mass ratioes, reclaims water extraction 4 ~ 6h, filters, and concentrated, spraying dry obtains water extract;
(4) mix: ethanol extract and water extract are mixed;
(5) pulp furnish: according to Chinese herbal medicine extract 25 parts, yeast culture 18 parts, KG 8 parts, betaine 7 parts, sodium acid carbonate 3 parts, ammonium chloride 6 parts, 4 parts, magnesium sulfate, the accurate proportioning raw material of chromium picolinate 2.5 parts of ratios;
(6) pulverize: after being pulverized by above-mentioned raw materials, cross 100-200 mesh sieve;
(7) mix: raw material after pulverizing is mixed, mixture homogeneity >=95%, obtain broiler chicken anti-heat stress, alleviate the feed addictive of oxidativestress damage.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.
Claims (1)
1. a feed addictive for broiler chicken anti-heat stress, alleviation oxidativestress damage, is characterized in that being made up of following mass fraction raw material: composite Chinese herbal extract 20 ~ 30 parts, yeast culture 15 ~ 20 parts, KG 5 ~ 10 parts, betaine 5 ~ 10 parts, sodium acid carbonate 2 ~ 4 parts, ammonium chloride 4 ~ 8 parts, 3 ~ 5 parts, magnesium sulfate, chromium picolinate 2 ~ 3 parts; Described composite Chinese herbal extract is the mixture of herbal raw material in alcohol extracting and water extraction after garden burnet 20 ~ 30 parts, dandelion 20 ~ 30 parts, Radix Isatidis 15 ~ 20 parts, spina date seed 10 ~ 15 parts, Chinese Fevervine Herb 10 ~ 15 parts, HERBA EPIMEDII 8 ~ 12 parts, the Radix Astragali 8 ~ 10 parts, Radix Angelicae Sinensis 8 ~ 10 parts, Herba Andrographitis 3 ~ 5 parts, Radix Glycyrrhizae 2 ~ 3 parts of ratio mixing.
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| CN201510858190.5A CN105309825A (en) | 2015-11-30 | 2015-11-30 | Feed additive capable of resisting heat stress and relieving oxidative stress injuries and used for broiler chickens |
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| CN201510858190.5A CN105309825A (en) | 2015-11-30 | 2015-11-30 | Feed additive capable of resisting heat stress and relieving oxidative stress injuries and used for broiler chickens |
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| CN105309825A true CN105309825A (en) | 2016-02-10 |
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Cited By (2)
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| CN107373077A (en) * | 2017-08-24 | 2017-11-24 | 浙江群大饲料科技股份有限公司 | A kind of additive premix for preventing and treating broiler chicken heat stress and preparation method thereof |
| CN108740478A (en) * | 2018-04-09 | 2018-11-06 | 河南科技大学 | A kind of herb extracts feed addictive of resisting heat stress of broiler chickens and preparation method thereof |
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