CN105288244A - Chinese herbal preparation for dissolving thrombus - Google Patents
Chinese herbal preparation for dissolving thrombus Download PDFInfo
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- CN105288244A CN105288244A CN201510857804.8A CN201510857804A CN105288244A CN 105288244 A CN105288244 A CN 105288244A CN 201510857804 A CN201510857804 A CN 201510857804A CN 105288244 A CN105288244 A CN 105288244A
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Abstract
The invention discloses a Chinese herbal preparation for dissolving thrombus, the Chinese herbal preparation is prepared by taking gastrodia elata and polygonum multiflorum as guiding drugs, taking hawthorn, leech, earthworm, safflower carthamus, the root of red-rooted salvia, pseudo-ginseng, isatis root, honeysuckle and dandelion as raw materials, pulverizing, grinding into fine powder, and mixing with honey to prepare honeyed boluses, wherein a weight ratio of the respective raw materials is as follows: 5 parts of hawthorn, 3 parts of leech, 8 parts of earthworm, 5 parts of safflower carthamus, 5 parts of the root of red-rooted salvia, 3 parts of pseudo-ginseng, 6 parts of isatis root, 6 parts of honeysuckle, 9 parts of dandelion and 15 parts of honey. The Chinese herbal preparation has the beneficial effects of low production cost, good thrombus prevention and treatment effect, high healing rate, fast effecting speed, and suitability for preventing and treating phlebothrombosis, artery thrombosis and microcirculation thrombus diseases as well as the treatment of inflammation thrombus diseases.
Description
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation compound method of thrombus embolism class diseases.
Background technology
Thrombotic disease is that current harm humans is healthy, causes one of reason that case fatality rate is the highest, as myocardial infarction, cerebral thrombosis, venous thrombosis, cerebral embolism, pulmonary infarction etc.In addition, thrombosis is the important pathological process of one related in numerous disease pathogenesis.Therefore, antithrombotic, treatment thrombosis, by established thromboembolism, has become prevention and controls important on Present clinical.
It is slow that phlebothrombosis refers at venous blood flow, under high blood coagulation state and blood vessel internal membrane damage condition, and vein generation acute nonsuppurative inflammation, and the disease that secondary thrombus is formed.Most venous thrombosis occur in the Deep venou of pelvic cavity and lower limb.
Arterial thrombus is formed mostly on atherosclerotic basis.Because in tremulous pulse, blood flow rate is high, even if so coagulation process is activated, enough thrombins can not be put aside in local, only make platelet adhesion reaction, gathering at atheromatous plaque ulceration, the endotheliocyte Shi Caihui that sustains damage, cause luminal stenosis, make the thrombin of local savings valid density.Thrombin makes conversion of fibrinogen fibroblast cells and forms thrombosis.Atherosclerosis except with some congenital factors mutually outside the Pass, mostly relevant with dietary life habits.Dietary structure is unreasonable, and higher fatty acid, the high confectionery thing of a large amount of absorption can increase ill probability.In addition, smoking, excessive drinking, shortage motion are also the key factors of artery thrombosis.
Microcirculation thrombosis is deposited as main fibrinous thrombus with fibrinous, or claims hyaline thrombus, and microvascular thrombosis due to microcirculation disturbance, can cause intravascular coagulation; Also can block thin vessels by the embolus that comes off, or cause fibrin deposition because of some factor coup injury capillary endothelium, common are DIC, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura etc.
Thrombotic disease is divided into phlebothrombosis, arterial thrombus, microcirculation thrombosis according to happening part, its each pathogenesis difference treatment is also had any different, but anticoagulant therapy is all the primary link in all treatments.Treatment thrombotic disease method has a lot, integrative therapy medicine is also very many, but Chinese traditional treatment be it is believed that gentleer always, smaller to the injury of health, be applicable to long-time conditioning, Chinese medicine especially modern Chinese medicine treatment thrombosis safety good, long-lasting good, prevention and prognostic good, but lack the types of drugs of prevention of thromboembolic disorders at present, still lack the types of drugs for the treatment of thrombotic disease, still lack the general prescription for the treatment of thrombotic disease, still await the Chinese medicine preparation developing treatment thrombotic disease better efficacy, particularly take effect slowly to there being the embolism class diseases of inflammation to remain at traditional Chinese medical prescription, cure rate is not high, the limitations such as simple personalized prescription therapeutic.
Therefore prior art haves much room for improvement and develops.
Summary of the invention
The object of the invention is to increase thrombolytic types of drugs, theoretical and the process technology according to Chinese medicine and pharmacy, a kind of prevention is provided and treatment thrombosis is effective, product cost is low, cure rate is high, instant effect, to the general Chinese medicine preparation of prevention and therapy thrombotic disease.
The object of the present invention is achieved like this:
A kind of thrombolytic Chinese medicine preparation, it is characterized in that with Rhizoma Gastrodiae and Radix Polygoni Multiflori for guiding drug, with Fructus Crataegi, Hirudo, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci for raw material, after being ground into fine powder, be mixed and made into honeyed pill with Mel, each raw material weight proportioning is: Hirudo 3, Pheretima 8, Flos Carthami 5, Radix Salviae Miltiorrhizae 5, Radix Notoginseng 3, Radix Isatidis 6, Flos Lonicerae 6, Herba Taraxaci 9, Mel 15.
Described honey raw material is preferentially gathered Fresh Honey;
Described pulverizing is pulverized and make 80-300 object fine powder Hirudo, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci;
Described honeyed pill of making, after the Hirudo being ground into fine powder, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci being mixed with Mel, makes thrombolytic Chinese medicine pill;
The present invention also can decoction, gets the crude drug of above-mentioned parts by weight, gram to be proportioning unit mix homogeneously, is decocted in water for oral dose, every day potion, the individual course for the treatment of on every Mondays.
The pharmacological property of each raw material components of the present invention is as follows:
Hirudo popular name Hirudo, also known as money trematodiasis, has multiple medicinal function, as having a kind of hirudin in Hirudo saliva, can the activity of Trombin inhibiting, and fiber can be formed receive albumen by cloudy only Fibrinogen, thus inhibit the formation of thrombosis; Ancient medical science utilizes Hirudo to have blood to suck traumatic patient, reaches the object of cleaning blood stasis; Tcm internal medicine, by brewed for dried polypide patent medicine, treats abdominal mass block, blood stasis, amenorrhea, traumatic injury etc.Modern medicine studies proof further, and Hirudo has specially good effect for anti-smelting cardiovascular and cerebrovascular disease and anticancer etc.Increase gradually with the Chinese patent medicine controlling heart and brain blood disorders disease that Hirudo preparation is produced in recent years.
Pheretima has another name called LUMBRICUS, Lumbricus, and the traditional Chinese medical science thinks that Pheretima is cold in nature, salty in the mouth.Heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis; Twitch for unconsciousness due to high fever infantile convulsion, joint is benumbed, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, vascular hypertension.
Flos Carthami has promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain effect.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Radix Salviae Miltiorrhizae is bitter, is slightly cold, GUIXIN, Liver Channel.Have promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind effect.Cure mainly menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Radix Notoginseng has another name called Radix Notoginseng, is Umbellales Araliaceae, is mainly distributed in the ground such as Yunnan, Guangxi, Jiangxi, Sichuan.Chinese crude drug Radix Notoginseng is using its root as medicinal effects, has dissipating blood stasis hemostasis, effect of subduing swelling and relieving pain.Cure mainly spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, and breast ventral spine pain, tumbling down swells and ache.
Radix Isatidis has heat clearing away, removing toxic substances, removing heat from blood effect.Control influenza, epidemic encephalitis, encephalitis b, pneumonia, erysipelas, pyretic toxicity sends out speckle, and coma tells nosebleed, pharyngeal swelling, mumps, acute catarrhal conjunctivitis, skin ulcer rash, and crimson tongue is purple dark, sore throat, scarlet fever, major part pestilence, carbuncle; Epidemic encephalitis type B, acute, chronic hepatitis, mumps, myelitic effect can be prevented and treated.
Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times, its property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, and fragrance thoroughly reaches and can be eliminating evil.Can dispelling wind-heat, also kind removing summer-heat blood poison, for various febrile disease, as fever of the body, dermexanthesis, sends out the diseases such as speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, equal Be very effective.
Herba Taraxaci has another name called Herba crotalariae albidae, wild everywhere, get very just, it is the dry herb of Compositae herbaceos perennial Herba Taraxaci, cold in nature, bitter in the mouth, sweet, and enter liver, stomach warp, effect of tool heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, belongs to antipyretic and antidotal type medicine in Chinese herbal medicine.Mash with fresh Herba Taraxaci traditionally, external application affected part, or it is for oral administration to decoct separately water, is used for the diseases such as treatment skin ulcer furuncle, acute mastitis.Discovered in recent years, Herba Taraxaci is also used widely in anti-inflammatory analgetic, can be rated as " broad ectrum antibiotic " of Chinese medicine.
Mel sweet taste is mellow and fragrant, and include the nutrient substance such as abundant glucose, fructose and calcium, phosphorus, ferrum and vitamin, it is not only nutritious, and medical value is high." book on Chinese herbal medicine " describes: " and hundred medicines, take strong will for a long time and make light of one's life by commiting suicide, ring is not prolonged life always." the successive dynasties traditional Chinese medical science all think have heat clearing away, invigorating middle warmer, detoxify, moisturize, improving eyesight, improving eyesight, cough-relieving, relieving constipation function.Modern medicine is using its ancillary drug as treatment hepatitis, liver cirrhosis, neurasthenia, gastric ulcer, hypertension, heart disease and cholecystitis.Mel and have the effect of coronary artery dilator and cardiac nutrition, improves myocardial function, has regulating action to blood pressure.
The each raw material components of the present invention has carried out science organically compatibility, with Hirudo in prescription, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng plays the merit of thrombus altogether, the formation of thrombosis is suppressed with Hirudo, with Pheretima heat clearing away dredging collateral, strengthen gastrointestinal disturbances effect, with Flos Carthami promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, with Radix Salviae Miltiorrhizae promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind, stop blooding with Radix Notoginseng dissipating blood stasis, subduing swelling and relieving pain, with Radix Isatidis, Flos Lonicerae, Herba Taraxaci anti-inflammation, removing toxic substances pain relieving, each component is mutually promoted, cooperatively interact, coordinating effect, strengthen the effect of body Integrate adjustment, reduce blood viscosity, promote blood flow, improve microcirculation, improve antioxidant ability of organism, to reach promoting blood circulation to remove obstruction in the collateral, thrombolytic object.
The invention has the advantages that: add thrombolytic herbal species, production cost is low, prevention with treat that thrombosis is effective, cure rate is high, instant effect, being applicable to prevention and treatment phlebothrombosis, arterial thrombus, microcirculation thrombus disease, being also applicable to the treatment to there being inflammation blood embolization disease.
Below in conjunction with specific embodiment, this technology is further described.
Detailed description of the invention:
Embodiment 1: gather and take Fresh Honey, for subsequent use; Gather finished product Hirudo on market, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci is ground into 100 fine powders, for subsequent use;
By being ground into the Hirudo 30 grams of fine powder, Pheretima 80 grams, 50 grams, Flos Carthami, Radix Salviae Miltiorrhizae 50 grams, Radix Notoginseng 30 grams, Radix Isatidis 60 grams, Flos Lonicerae 60 grams, Herba Taraxaci 90 grams mix with Mel 150 grams, be processed into Chinese medicine pill, namely make thrombolytic Chinese medicine pill preparation of the present invention.
Embodiment 2: gather and take Fresh Honey, respectively uses; Gather finished product Hirudo on market, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci is ground into 150 fine powders, for subsequent use;
By being ground into the Hirudo 300 grams of fine powder, Pheretima 800 grams, 500 grams, Flos Carthami, Radix Salviae Miltiorrhizae 500 grams, Radix Notoginseng 300 grams, Radix Isatidis 600 grams, Flos Lonicerae 600 grams, Herba Taraxaci 900 grams mix with Mel 1500 grams, be processed into Chinese medicine pill, namely make thrombolytic Chinese medicine pill preparation of the present invention.
Embodiment 3: gather and take Fresh Honey, for subsequent use; Gather finished product Hirudo on market, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci is ground into 300 fine powders, for subsequent use;
By being ground into the Hirudo 15 grams of fine powder, Pheretima 40 grams, 25 grams, Flos Carthami, Radix Salviae Miltiorrhizae 25 grams, Radix Notoginseng 15 grams, Radix Isatidis 30 grams, Flos Lonicerae 30 grams, Herba Taraxaci 45 grams mix with Mel 75 grams, be processed into Chinese medicine pill, namely make thrombolytic Chinese medicine pill preparation of the present invention.The foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, for a person skilled in the art, the present invention can have various modifications and variations.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (2)
1. a thrombolytic Chinese medicine preparation, it is characterized in that with Rhizoma Gastrodiae and Radix Polygoni Multiflori for guiding drug, with Fructus Crataegi, Hirudo, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci for raw material, after being ground into fine powder, be mixed and made into honeyed pill with Mel, each raw material weight proportioning is: Fructus Crataegi 5, Hirudo 3, Pheretima 8, Flos Carthami 5, Radix Salviae Miltiorrhizae 5, Radix Notoginseng 3, Radix Isatidis 6, Flos Lonicerae 6, Herba Taraxaci 9, Mel 15.
2. the thrombolytic Chinese medicine preparation of one according to claim 1, it is characterized in that described honeyed pill, after the Hirudo being ground into fine powder, Pheretima, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Notoginseng, Radix Isatidis, Flos Lonicerae, Herba Taraxaci being mixed with Mel, makes thrombolytic Chinese medicine pill.
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| CN201510857804.8A CN105288244A (en) | 2015-11-30 | 2015-11-30 | Chinese herbal preparation for dissolving thrombus |
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| CN201510857804.8A CN105288244A (en) | 2015-11-30 | 2015-11-30 | Chinese herbal preparation for dissolving thrombus |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998247A (en) * | 2016-06-17 | 2016-10-12 | 齐齐哈尔市第医院 | Traditional Chinese medicine for treating carotid plaque |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130058519A (en) * | 2011-11-25 | 2013-06-04 | 안동대학교 산학협력단 | Composition comprising the extract of cedrela sonensis a. juss for prevention or control of thrombosis |
| CN105079103A (en) * | 2014-05-09 | 2015-11-25 | 宋修文 | Traditional Chinese medicine preparation for preventing and treating thrombus |
-
2015
- 2015-11-30 CN CN201510857804.8A patent/CN105288244A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20130058519A (en) * | 2011-11-25 | 2013-06-04 | 안동대학교 산학협력단 | Composition comprising the extract of cedrela sonensis a. juss for prevention or control of thrombosis |
| CN105079103A (en) * | 2014-05-09 | 2015-11-25 | 宋修文 | Traditional Chinese medicine preparation for preventing and treating thrombus |
Non-Patent Citations (1)
| Title |
|---|
| 崔晓丽: "《24节气养生食补大全》", 30 November 2012, 福建科学技术出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998247A (en) * | 2016-06-17 | 2016-10-12 | 齐齐哈尔市第医院 | Traditional Chinese medicine for treating carotid plaque |
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Application publication date: 20160203 |
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