CN105267890A - Traditional Chinese medicine formula for treating lung cancer - Google Patents
Traditional Chinese medicine formula for treating lung cancer Download PDFInfo
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- CN105267890A CN105267890A CN201510864814.4A CN201510864814A CN105267890A CN 105267890 A CN105267890 A CN 105267890A CN 201510864814 A CN201510864814 A CN 201510864814A CN 105267890 A CN105267890 A CN 105267890A
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating a lung cancer. The traditional Chinese medicine is prepared from the following traditional Chinese medicinal materials in parts by weight: 15-20 parts of pinellia ternate, 15-20 parts of mangnolia officinalis, 10-15 parts of rhizoma arisaematis, 15-20 parts of whitebackleaf mallotus roots, 15-20 parts of calamus, 10-15 parts of small diuranthera roots, 5-10 parts of gmelin sealavender herb, 10-15 parts of fructus evodiae, 10-15 parts of common perilla, 10-15 parts of fiveleaf akebia fruits, 10-15 parts of pericarpium citri reticulatae, 15-20 parts of draba nemorosa, 10-15 parts of arisaema cum bile, 10-15 parts of gerbera delauayi franch, 10-15 parts of curcuma aromatic and 5-10 parts of rhizoma corydalis. The traditional Chinese medicine formula has the advantages that the used traditional Chinese medicine accords with the regulation of the Chinese pharmacopoeia, and is safe and reliable; a plurality of medicines are combined to reach the efficacies of eliminating dampness, eliminating phlegm, tonifying the spleen, regulating qi and the like; and the traditional Chinese medicine has the characteristics of being accurate in curative effect on the lung cancer caused by phlegm-damp obstructing the lung, fast in acting, high in recovery rate, free of a side effect and the like.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly a kind of Chinese medicine formula for the treatment of pulmonary carcinoma.
Background technology
It is the fastest that pulmonary carcinoma is that M & M increases, to one of population health and the maximum malignant tumor of life threat.The many countries of immediate and mid-term all report that the M & M of pulmonary carcinoma all obviously increases, and male lung cancer M & M all accounts for first of all malignant tumor, and women's sickness rate accounts for second, and mortality rate accounts for second.The cause of disease of pulmonary carcinoma is still not exclusively clear and definite so far, and great mass of data shows, long-term a large amount of smoking and pulmonary carcinoma have very close relationship.Existing research proves: the probability that long-term a large amount of smoker suffers from pulmonary carcinoma is 10 ~ 20 times of non-smoker, and the age starting smoking is less, and the probability of suffering from pulmonary carcinoma is higher.
Pulmonary carcinoma originates from bronchial mucosa epithelium, is confined to person in basement membrane and is called cancer in situ.Cancerous protuberance can in bronchial lumen or/and close on lung tissue growth, and by lymph, blood or through bronchus transfer diffusion.The situation of cancer growth speed and transfer diffusion and the biological characteristics such as histological type, differentiation degree of carcinoma have certain relation.
The distribution situation of pulmonary carcinoma, right lung is more than left lung, and upper leaf is more than inferior lobe.All cancerous protuberance can be there is from main bronchus to bronchioles.Originate from the pulmonary carcinoma of main bronchus, lobar bronchi, position, near hilus pulumonis person, is called central type carcinoma of lung; Originate from the pulmonary carcinoma of below segmental bronchi, position, peripheral part person of lung, is called peripheral pulmonary carcinoma.
Operation, radiation and chemotherapy are the primary treatments for the treatment of medium and advanced lung cancer, and especially chemotherapeutic treatment, the pulmonary carcinoma of more than 90% needs to accept chemotherapeutic treatment.But chemotherapy effectively can hinder cancerous cell, can normal cell be killed and wounded and cause the immunologic function of patient suppressed again simultaneously, occur more complication, bring very big damage to patient body.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine formula for the treatment of pulmonary carcinoma, be particularly useful for treatment phlegm dampness in lungs type pulmonary carcinoma, it is evident in efficacy, safe and reliable, have no side effect, there is wide potential applicability in clinical practice.
The invention provides a kind of Chinese medicine formula for the treatment of pulmonary carcinoma, formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 15 ~ 20 parts, Cortex Magnoliae Officinalis 15 ~ 20 parts, Rhizoma Arisaematis 10 ~ 15 parts, Folium Malloti Apeltae 15 ~ 20 parts, Rhizoma Acori Calami 15 ~ 20 parts, Radix Diurantherae Minoris 10 ~ 15 parts, Herba Limonii Gmelinii 5 ~ 10 parts, Fructus Evodiae 10 ~ 15 parts, common perilla 10 ~ 15 parts, Fructus Akebiae 10 ~ 15 parts, Pericarpium Citri Reticulatae 10 ~ 15 parts, Semen Lepidii 15 ~ 20 parts, Arisaema Cum Bile 10 ~ 15 parts, Bai Ye do not turn over 10 ~ 15 parts, Radix Curcumae 10 ~ 15 parts, Rhizoma Corydalis 5 ~ 10 parts.
Wherein, preferred version is as follows:
Can be formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 15 parts, Cortex Magnoliae Officinalis 15 parts, Rhizoma Arisaematis 10 parts, Folium Malloti Apeltae 15 parts, Rhizoma Acori Calami 15 parts, Radix Diurantherae Minoris 10 parts, Herba Limonii Gmelinii 5 parts, Fructus Evodiae 10 parts, common perilla 10 parts, Fructus Akebiae 10 parts, Pericarpium Citri Reticulatae 10 parts, Semen Lepidii 15 parts, Arisaema Cum Bile 10 parts, Bai Ye do not turn over 10 parts, Radix Curcumae 10 parts, Rhizoma Corydalis 5 parts.
Also can be formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 20 parts, Cortex Magnoliae Officinalis 20 parts, Rhizoma Arisaematis 15 parts, Folium Malloti Apeltae 20 parts, Rhizoma Acori Calami 20 parts, Radix Diurantherae Minoris 15 parts, Herba Limonii Gmelinii 10 parts, Fructus Evodiae 15 parts, common perilla 15 parts, Fructus Akebiae 15 parts, Pericarpium Citri Reticulatae 15 parts, Semen Lepidii 20 parts, Arisaema Cum Bile 15 parts, Bai Ye do not turn over 15 parts, Radix Curcumae 15 parts, Rhizoma Corydalis 10 parts.
Also can be formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 18 parts, Cortex Magnoliae Officinalis 18 parts, Rhizoma Arisaematis 12 parts, Folium Malloti Apeltae 18 parts, Rhizoma Acori Calami 18 parts, Radix Diurantherae Minoris 12 parts, Herba Limonii Gmelinii 8 parts, Fructus Evodiae 12 parts, common perilla 12 parts, Fructus Akebiae 12 parts, Pericarpium Citri Reticulatae 12 parts, Semen Lepidii 18 parts, Arisaema Cum Bile 12 parts, Bai Ye do not turn over 12 parts, Radix Curcumae 12 parts, Rhizoma Corydalis 8 parts.
By the concrete preparation method that above-mentioned each crude drug makes medicine of the present invention be:
Take raw material of Chinese medicine according to formula and join in container, adding water covers powder and soaks 10 ~ 20 minutes, then adds water and no powder 3 ~ 5 centimetres, decocts with high heat and uses slow fire boiling again instead 20 ~ 30 minutes to seething with excitement, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Usage: be grown up each serving with 200 ~ 300mL, every day 2 times, after meal half an hour decoction being taken warmly, within 15 days, be a course for the treatment of.
Pharmacology analysis:
The Rhizoma Pinelliae: pungent, temperature.Return spleen, stomach, lung meridian.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.For abundant expectoration cough with asthma, phlegm retention vertigo and palpitation, dizziness due to wind-phlegm, syncope due to accumulation of phlegm is had a headache, vomiting regurgitation, and breast gastral cavity painful abdominal mass is vexed, globus hystericus; Raw with external treatment carbuncle sucutaneous nodule.Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) is used for stopping nausea and vomiting by lowering the adverse flow of QI.
Cortex Magnoliae Officinalis: bitter, pungent, temperature.Return spleen, stomach, lung, large intestine channel.Dampness expectorant, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.
Rhizoma Arisaematis: bitter, pungent, temperature.Return lung, liver, spleen channel.Drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.For pertinacious phlegm cough, dizziness due to wind-phlegm, middle wind-phlegm is stopped up, facial hemiparalysis, hemiplegia, epilepsy, infantile convulsion, tetanus.Life uses external treatment carbuncle, snake bite and insect sting.
Folium Malloti Apeltae: be used as medicine with root.Micro-hardship, puckery, flat.Easing the affected liver is invigorated blood circulation, invigorating the spleen for eliminating dampness, and convergence is solid de-.For chronic hepatitis, hepatosplenomegaly, uterine prolapse, proctoptosis, leucorrhea, edema during pregnancy.
Rhizoma Acori Calami: toil, temperature.Reduce phlegm, have one's ideas straightened out, spleen invigorating, dampness removing.Control epilepsy, palpitate with fear forgetful, mind is not asked, and humidity hysteresis painful abdominal mass is swollen, dysentery, rheumatalgia, carbuncle scabies.
Radix Diurantherae Minoris: light is flat.Heat-clearing and toxic substances removing, strong swollen dampness removing.Dispelling the wind and dampness pathogens, infantile malnutrition, mastitis, venom.
Herba Limonii Gmelinii: bitter, salty, temperature.Invigorate blood circulation, hemostasis, warming middle-JIAO and strengthening the spleen, strengthening by means of tonics.For menoxenia, dysfunctional uterine hemorrhage, bleeding hemorrhoids, gastric ulcer, insufficiency of the spleen edema.
Fructus Evodiae: acrid in the mouth, temperature.Enter liver, spleen, stomach, large intestine, kidney channel.Warming middle-JIAO, pain relieving, regulates the flow of vital energy, dampness, and stopping vomiting is against acid regurgitation, and headache due to JUE YIN disorder, the coldness of ZANG-organ is vomited and diarrhoea, abdominal distention, abdominal pain during menstruation, Diarrhoea, vascular hypertension, beriberi, hernia, aphthous ulcer, toothache, eczema, impetigo.
Common perilla: pungent, temperature.Expelling cold and relieving exterior syndrome, regulating the flow of QI to ease the stomach.For anemofrigid cold, headache, cough, distension and fullness of the chest and abdomen.
Fructus Akebiae: warm in nature flat, bitter and puckery flavor is pungent, nontoxic.Liver-smoothing, qi-regulating, promoting blood circulation and stopping pain, relieving restlessness diuresis.Treating the liver peratodynia, gastric heat food is slow-witted, excessive thirst, also Hakuri, lumbago, hypochondriac pain, hernia, cave warp, and uterus drops.
Pericarpium Citri Reticulatae: bitter, pungent, temperature.Return lung, spleen channel.Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.
Semen Lepidii: pungent, bitter, Great Cold.Return lung, urinary bladder channel.Eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema.
Arisaema Cum Bile: bitter, micro-pungent, cool.Return lung, liver, spleen channel.Removing heat-phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion.
Bai Ye does not turn over: acrid in the mouth, micro-hardship; Property is put down.Removing heat-phlegm, removing food stagnancy kills early.Main flu, cough and asthma, dysentery, stomachache, dyspepsia, ascariasis, traumatic hemorrhage.
Radix Curcumae: pungent, bitter, cold.Return liver, the heart, lung meridian.Regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
In Chinese medicine formula of the present invention, the Rhizoma Pinelliae, Cortex Magnoliae Officinalis, Rhizoma Arisaematis drying dampness to eliminate phlegm; Folium Malloti Apeltae, Rhizoma Acori Calami, Radix Diurantherae Minoris, Herba Limonii Gmelinii, Fructus Evodiae, common perilla, Fructus Akebiae, Pericarpium Citri Reticulatae spleen invigorating are regulated the flow of vital energy; Semen Lepidii eliminating the pathogens from the lung row water; Arisaema Cum Bile, Bai Ye do not turn over and go out for the yellow sticky difficulty of expectorant; Radix Curcumae, Rhizoma Corydalis are used for distending pain in the chest and hypochondrium.
The invention has the advantages that used Chinese medicine meets Pharmacopoeia of People's Republic of China regulation, safety of medicine is reliable.All medicine phases and have effects such as promoting drying dampness to eliminate phlegm, spleen invigorating to regulate the flow of vital energy, treatment phlegm dampness in lungs type pulmonary carcinoma has that determined curative effect, instant effect, cure rate are high, the feature such as have no side effect.
Outcome measure:
The present invention carries out clinical observation treatment to 175 routine patients with lung cancer, wherein age reckling 25 years old, the maximum 78 years old, 54 years old mean age; Man 94 example, female 81 example.
Therapeutic Method: be grown up each serving with 200 ~ 300mL, every day 2 times, after meal half an hour decoction being taken warmly, within 15 days, be a course for the treatment of.
Efficacy assessment standard:
Clinical disease criterion of therapeutical effect by cough, cough up phlegm, expectorant blood, uncomfortable in chest, chest pain, the common sympton such as out of breath, heating by light, in, be heavily divided into 3 grades, be designated as 2,4,6 points respectively, carrying out accumulation before the treatment afterwards contrasts, by integration than method Estimating curative effect.
Effective: after treatment, symptom and sign integrated value declines >=2/3;
Effective: after treatment, symptom and sign integrated value declines >=1/3, but < 2/3;
Invalid: not reach effective standard person.
Result: effective 102 examples, account for 58.3%, effective 72 examples, account for 41.1%, and invalid 1 example, accounts for 0.6%, total effective rate 99.4%.
Model case:
Case 1: Zhang, man, 58 years old, people from Qingdao.Patient's self-induction health does not relax, and cough, spit, chest pain, has a fever 39.5 degree.Rabat is made, CT, bronchoscope to local hospital, be diagnosed as: left lung centre type lung squamous cancer, tumor 3 × 4cm, after radiotherapy chemotherapy, the state of an illness does not take a turn for the better, and continues fever two months, uses some febrifuge, can only alleviate in short-term, then go to a doctor in here, gives Chinese medicine of the present invention and treat, effective after January, clinical symptom disappearance, follows up a case by regular visits to half a year without recurrence.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine formula for pulmonary carcinoma, formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 15 parts, Cortex Magnoliae Officinalis 15 parts, Rhizoma Arisaematis 10 parts, Folium Malloti Apeltae 15 parts, Rhizoma Acori Calami 15 parts, Radix Diurantherae Minoris 10 parts, Herba Limonii Gmelinii 5 parts, Fructus Evodiae 10 parts, common perilla 10 parts, Fructus Akebiae 10 parts, Pericarpium Citri Reticulatae 10 parts, Semen Lepidii 15 parts, Arisaema Cum Bile 10 parts, Bai Ye do not turn over 10 parts, Radix Curcumae 10 parts, Rhizoma Corydalis 5 parts.
Embodiment 2:
Treat a Chinese medicine formula for pulmonary carcinoma, formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 20 parts, Cortex Magnoliae Officinalis 20 parts, Rhizoma Arisaematis 15 parts, Folium Malloti Apeltae 20 parts, Rhizoma Acori Calami 20 parts, Radix Diurantherae Minoris 15 parts, Herba Limonii Gmelinii 10 parts, Fructus Evodiae 15 parts, common perilla 15 parts, Fructus Akebiae 15 parts, Pericarpium Citri Reticulatae 15 parts, Semen Lepidii 20 parts, Arisaema Cum Bile 15 parts, Bai Ye do not turn over 15 parts, Radix Curcumae 15 parts, Rhizoma Corydalis 10 parts.
Embodiment 3:
Treat a Chinese medicine formula for pulmonary carcinoma, formulated by the raw material of Chinese medicine of following parts by weight: the Rhizoma Pinelliae 18 parts, Cortex Magnoliae Officinalis 18 parts, Rhizoma Arisaematis 12 parts, Folium Malloti Apeltae 18 parts, Rhizoma Acori Calami 18 parts, Radix Diurantherae Minoris 12 parts, Herba Limonii Gmelinii 8 parts, Fructus Evodiae 12 parts, common perilla 12 parts, Fructus Akebiae 12 parts, Pericarpium Citri Reticulatae 12 parts, Semen Lepidii 18 parts, Arisaema Cum Bile 12 parts, Bai Ye do not turn over 12 parts, Radix Curcumae 12 parts, Rhizoma Corydalis 8 parts.
Embodiment 4:
Embodiment 1 ~ 3 is prepared in accordance with the following methods: take raw material of Chinese medicine according to formula and join in container, adds water to cover powder and soak 10 ~ 20 minutes, then adds water and no powder 3 ~ 5 centimetres, decocts with high heat and uses slow fire boiling again instead 20 ~ 30 minutes to seething with excitement, get filtrate; And then add water and do not have powder 3 ~ 5 centimetres, decoct with high heat and uses slow fire boiling again instead 15 ~ 20 minutes to boiling, then remove slag and get filtrate, twice filtrate merges.
Usage: be grown up each serving with 200 ~ 300mL, every day 2 times, after meal half an hour decoction being taken warmly, within 15 days, be a course for the treatment of.
Claims (4)
1. treat a Chinese medicine formula for pulmonary carcinoma, it is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: the Rhizoma Pinelliae 15 ~ 20 parts, Cortex Magnoliae Officinalis 15 ~ 20 parts, Rhizoma Arisaematis 10 ~ 15 parts, Folium Malloti Apeltae 15 ~ 20 parts, Rhizoma Acori Calami 15 ~ 20 parts, Radix Diurantherae Minoris 10 ~ 15 parts, Herba Limonii Gmelinii 5 ~ 10 parts, Fructus Evodiae 10 ~ 15 parts, common perilla 10 ~ 15 parts, Fructus Akebiae 10 ~ 15 parts, Pericarpium Citri Reticulatae 10 ~ 15 parts, Semen Lepidii 15 ~ 20 parts, Arisaema Cum Bile 10 ~ 15 parts, Bai Ye do not turn over 10 ~ 15 parts, Radix Curcumae 10 ~ 15 parts, Rhizoma Corydalis 5 ~ 10 parts.
2. a kind of Chinese medicine formula for the treatment of pulmonary carcinoma according to claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: the Rhizoma Pinelliae 15 parts, Cortex Magnoliae Officinalis 15 parts, Rhizoma Arisaematis 10 parts, Folium Malloti Apeltae 15 parts, Rhizoma Acori Calami 15 parts, Radix Diurantherae Minoris 10 parts, Herba Limonii Gmelinii 5 parts, Fructus Evodiae 10 parts, common perilla 10 parts, Fructus Akebiae 10 parts, Pericarpium Citri Reticulatae 10 parts, Semen Lepidii 15 parts, Arisaema Cum Bile 10 parts, Bai Ye do not turn over 10 parts, Radix Curcumae 10 parts, Rhizoma Corydalis 5 parts.
3. a kind of Chinese medicine formula for the treatment of pulmonary carcinoma according to claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: the Rhizoma Pinelliae 20 parts, Cortex Magnoliae Officinalis 20 parts, Rhizoma Arisaematis 15 parts, Folium Malloti Apeltae 20 parts, Rhizoma Acori Calami 20 parts, Radix Diurantherae Minoris 15 parts, Herba Limonii Gmelinii 10 parts, Fructus Evodiae 15 parts, common perilla 15 parts, Fructus Akebiae 15 parts, Pericarpium Citri Reticulatae 15 parts, Semen Lepidii 20 parts, Arisaema Cum Bile 15 parts, Bai Ye do not turn over 15 parts, Radix Curcumae 15 parts, Rhizoma Corydalis 10 parts.
4. a kind of Chinese medicine formula for the treatment of pulmonary carcinoma according to claim 1, is characterized in that by the raw material of Chinese medicine of following parts by weight formulated: the Rhizoma Pinelliae 18 parts, Cortex Magnoliae Officinalis 18 parts, Rhizoma Arisaematis 12 parts, Folium Malloti Apeltae 18 parts, Rhizoma Acori Calami 18 parts, Radix Diurantherae Minoris 12 parts, Herba Limonii Gmelinii 8 parts, Fructus Evodiae 12 parts, common perilla 12 parts, Fructus Akebiae 12 parts, Pericarpium Citri Reticulatae 12 parts, Semen Lepidii 18 parts, Arisaema Cum Bile 12 parts, Bai Ye do not turn over 12 parts, Radix Curcumae 12 parts, Rhizoma Corydalis 8 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105560682A (en) * | 2016-02-23 | 2016-05-11 | 青岛大学附属医院 | Traditional Chinese medicine prescription applied to preoperative adjuvant therapy of lung cancer |
| CN105617101A (en) * | 2016-02-22 | 2016-06-01 | 席新进 | Traditional Chinese medicine composition for treating lung cancer |
| CN106237076A (en) * | 2016-08-26 | 2016-12-21 | 余迎春 | A kind of Chinese medicine formula treating pulmonary carcinoma and preparation method thereof |
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| CN105617101A (en) * | 2016-02-22 | 2016-06-01 | 席新进 | Traditional Chinese medicine composition for treating lung cancer |
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Application publication date: 20160127 |
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