CN105249363B - A kind of black garlic capsule and preparation method thereof - Google Patents

A kind of black garlic capsule and preparation method thereof Download PDF

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Publication number
CN105249363B
CN105249363B CN201510773581.7A CN201510773581A CN105249363B CN 105249363 B CN105249363 B CN 105249363B CN 201510773581 A CN201510773581 A CN 201510773581A CN 105249363 B CN105249363 B CN 105249363B
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black garlic
garlic
powder
fermented
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CN105249363A (en
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乔旭光
李超男
李宁阳
卢晓明
邱志常
邢艳霞
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Shandong Agricultural University
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Shandong Agricultural University
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention belongs to functional food technical fields, are related to a kind of capsule preparations with healthcare function, and in particular to a kind of black garlic capsule and preparation method thereof, which includes following raw material:70 80 parts of fermented black garlic powder, 10 15 parts of black fungus powder, 35 parts of tricalcium phosphate, 23 parts of microcrystalline cellulose, 23 parts of glycerin monostearate, 35 parts of cornstarch.Fermented black garlic powder contained in black garlic capsule prepared by the present invention is by being added specific protease, and preparation time is short, and the capsule storage time of preparation is long, and dispersing uniformity is good, easily absorbs, and bioavilability is good.

Description

A kind of black garlic capsule and preparation method thereof
Technical field
The invention belongs to functional food technical fields, are related to a kind of capsule preparations with healthcare function, and in particular to A kind of black garlic capsule and preparation method thereof.
Background technology
Black garlic also known as black garlic, fermenting black garlic, be with fresh raw garlic raw material ferment after pretreatment made of food, it is black Garlic is main during blacking happens is that Maillard reactions, ultimately generate melanoidin, it not only remains uncooked garlic original Some ingredients, function, in terms of inoxidizability and physiological activity, the content of polyphenols be also higher by 5 times or more, super oxygen Object mutase(SOD)Activity is higher by 10 times or more than fresh garlic, and therefore, the development for black garlic deep processed product is that Chinese garlic provides Source opens new field.
Traditional black garlic preparation process, spontaneous fermentation 18 days or more under the conditions of high temperature and humidity mostly, required time is grown, and The black garlic of preparation needs to be stored under given conditions, and storage time is short, cannot reach requirement edible at any time.
Invention content
Long for the black garlic fermentation time of the existing technology, the problems such as storage time is short, the present invention provides a kind of black Garlic capsule, fermented black garlic powder preparation time contained in the black garlic capsule is short, and the capsule storage time of preparation is long, dispersing uniformity It is good, it easily absorbs, bioavilability is good.
The present invention also provides a kind of preparation methods of black garlic capsule, and this method preparation process is simple, by controlling raw material Addition sequence, so that each ingredient is acted synergistically, achieve the purpose that quickly to be absorbed and utilized.
Used technical solution is the present invention to achieve the goals above:
The present invention provides a kind of black garlic capsules, including following raw material:
70-80 parts of fermented black garlic powder, 10-15 parts of black fungus powder, 3-5 parts of tricalcium phosphate, 2-3 parts of microcrystalline cellulose are single hard 2-3 parts of glycerol, 3-5 parts of cornstarch;The fermented black garlic powder is that garlic is fermented after enzymolysis.
Further, the raw material of optimization is:80 parts of fermented black garlic powder, 12 parts of black fungus powder, 5 parts of tricalcium phosphate, crystallite 2 parts of cellulose, 3 parts of glycerin monostearate, 4 parts of cornstarch.
Fermenting raw materials black garlic powder needed for black garlic capsule of the present invention is prepared using following methods:
(1)After garlic peeling is cleaned, it is cut into garlic pieces, the papain for accounting for garlic weight 0.1% is then added, in 30- Under the conditions of 35 DEG C, 2-3h is hydrolyzed, then heats to 80-85 DEG C, is fermented 3 days, then at 88-90 DEG C, is fermented 7-9 days, Up to liquid state fermentation black garlic;
(2)Whey protein isolate is added in above-mentioned liquid state fermentation black garlic, particle is spray-dried to obtain after stirring evenly.
Further, the thickness of the garlic pieces is 2-4mm.
Further, the addition of the whey protein isolate is the 0.5% of liquid state fermentation black garlic weight.
Further, the condition of the spray drying is:150 ~ 160 DEG C of inlet temperature, 70 ~ 80 DEG C of outlet temperature, charging Speed 50ml/min.
The present invention also provides a kind of preparation methods of black garlic capsule, include the following steps:
(1)By parts by weight auricularia auriculajudae powder, 1/2 parts by weight cornstarch in be added 75% ethyl alcohol to solid content be 85-90%, stir Mixing makes it be uniformly dispersed, and obtains mixed liquor;
(2)Parts by weight fermented black garlic powder, tricalcium phosphate, microcrystalline cellulose, glycerin monostearate, the other half corn is taken to form sediment Powder is uniformly mixed, and is sieved with 100 mesh sieve, with high-speed mixing granulating machine mixing granulation, is obtained particle;
(3)Mixed liquor is added in particle, continues stirring granulation, is filled into Capsules i.e. after gained particle drying Can, every weight 0.5g.
By specific protease will be added in garlic when the present invention prepares fermented black garlic powder, can be by protein digestion Therefore polypeptide, brown stain speed promote the quickening of fermenting speed better than protein.Protein contained in black fungus powder, Fat, carbohydrate are nutritional ingredients needed by human, have nourishing, beneficial stomach, clearing lung-heat ease constipation and other effects, meanwhile, contain in fat constituent There is abundant lecithin lipoid substance, the molecular structure of lecithin is similar to the phospholipid molecule structure in intestinal epithelial cell membrane, when Lecithin is exchanged with cell membrane or direct embedded, and can increase intestinal epithelial cell membrane stays thing, enhances the suction of nutriment The property received.While tricalcium phosphate can replenish the calcium, the dispersing uniformity of particle can be improved as the anticaking agent of particle.The present invention Auricularia auriculajudae powder is formed simple cladding to other raw materials, can improve absorption of the human body to nutritional ingredient by the preparation method of offer.
Advantages of the present invention is:
(1)The black garlic capsule storage time is long, full of nutrition, and dispersing uniformity is good, and disintegration rate is preferable, easily absorbs, biology Availability is good.
(2)The black garlic fermentation time is short, improves efficiency.
Specific implementation mode
Specific example mode with reference to embodiments is again described in further detail the above of the present invention, but The range that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to embodiment below.
Papain used in the present invention is purchased from the Shanghai bio tech ltd Shi Feng.
Embodiment 1
(1)After garlic peeling is cleaned, it is cut into the garlic pieces that thickness is 2-4mm, the wood for accounting for garlic weight 0.1% is then added Melon protease hydrolyzes 3h under the conditions of 30 DEG C, then heats to 80 DEG C, ferments 3 days, then at 88 DEG C, ferments 9 days, Up to liquid state fermentation black garlic;
(2)Above-mentioned liquid state fermentation black garlic is added to the whey protein isolate for accounting for its weight 0.5%, is sprayed after stirring evenly dry It is dry:150 DEG C of inlet temperature, 70 DEG C, charging rate 50ml/min of outlet temperature, it is fermented black garlic powder to obtain particle;
(3)75% quantitative ethyl alcohol will be added in 12 parts of auricularia auriculajudae powders, 2 parts of cornstarch, stirring makes it be uniformly dispersed, must consolidate The mixed liquor that content is 90%;
(4)Take 80 parts of fermented black garlic powders, 5 parts of tricalcium phosphates, 2 parts of microcrystalline celluloses, 3 parts of glycerin monostearates, 2 parts of jade Rice starch is uniformly mixed, and sieves with 100 mesh sieve, 75% ethyl alcohol is then added, with high-speed mixing granulating machine mixing granulation, obtain particle;
(5)Mixed liquor is added in particle, continues stirring granulation, is filled into Capsules i.e. after gained particle drying Can, every weight 0.5g.
Embodiment 2
(1)After garlic peeling is cleaned, it is cut into the garlic pieces that thickness is 2-4mm, the wood for accounting for garlic weight 0.1% is then added Melon protease hydrolyzes 2.5h under the conditions of 35 DEG C, then heats to 83 DEG C, ferments 3 days, then at 89 DEG C, ferments 8 days i.e. It can be to get liquid state fermentation black garlic;
(2)Above-mentioned liquid state fermentation black garlic is added to the whey protein isolate for accounting for its weight 0.5%, is sprayed after stirring evenly dry It is dry:160 DEG C of inlet temperature, 80 DEG C, charging rate 50ml/min of outlet temperature, it is fermented black garlic powder to obtain particle;
(3)75% quantitative ethyl alcohol will be added in 15 parts of auricularia auriculajudae powders, 2.5 parts of cornstarch, stirring makes it be uniformly dispersed, obtains The mixed liquor that solid content is 85%;
(4)Take 70 parts of fermented black garlic powders, 3 parts of tricalcium phosphates, 3 parts of microcrystalline celluloses, 3 parts of glycerin monostearates, 2.5 parts Cornstarch is uniformly mixed, and sieves with 100 mesh sieve, 75% ethyl alcohol is then added, with high-speed mixing granulating machine mixing granulation, obtain particle;
(5)Mixed liquor is added in particle, continues stirring granulation, is filled into Capsules i.e. after gained particle drying Can, every weight 0.5g.
Embodiment 3
(1)After garlic peeling is cleaned, it is cut into garlic pieces, the papain for accounting for garlic weight 0.1% is then added, Under the conditions of 32 DEG C, 2h is hydrolyzed, then heats to 85 DEG C, is fermented 3 days, then at 90 DEG C, fermentation can be sent out for 7 days to get liquid Ferment black garlic;
(2)Above-mentioned liquid state fermentation black garlic is added to the whey protein isolate for accounting for its weight 0.5%, is sprayed after stirring evenly dry It is dry:155 DEG C of inlet temperature, 78 DEG C, charging rate 50ml/min of outlet temperature, it is fermented black garlic powder to obtain particle;
(3)75% quantitative ethyl alcohol will be added in 10 parts of auricularia auriculajudae powders, 1.5 parts of cornstarch, stirring makes it be uniformly dispersed, obtains The mixed liquor that solid content is 90%;
(4)Take 76 parts of fermented black garlic powders, 4 parts of tricalcium phosphates, 3 parts of microcrystalline celluloses, 2 parts of glycerin monostearates, 1.5 parts Cornstarch is uniformly mixed, and sieves with 100 mesh sieve, 75% ethyl alcohol is then added, with high-speed mixing granulating machine mixing granulation, obtain particle;
(5)Mixed liquor is added in particle, continues stirring granulation, is filled into Capsules i.e. after gained particle drying Can, every weight 0.5g.
Comparative example 1
Fermented black garlic powder using step temperature rising formula through under hot and humid environment, being fermented:After garlic is cleaned first, 55-60 DEG C of temperature, humidity lower fermentation 30 days under the conditions of being 70%.
Comparative example 2
Compared with embodiment 1, it is added without black fungus powder, other preparation methods and raw material composition are identical with embodiment 1.
Interpretation of result
1. fermented black garlic powder D1 prepared by 1 fermented black garlic powder S1 of embodiment and comparative example 1 is carried out nutritional ingredient detection, tool Body the results are shown in Table 1.
Soluble sugar content is measured by phenol-sulfuric acid and colorimetric method.
Total phenol content is measured by Folin-Phenol colorimetric method.
SOD(Antioxidant activity)It is measured by assay NBT photoreduction.
Often there were significant differences between for capable different alphabet registrations in table(P < 0.05).
From table 1 it follows that the fermentation that fermented black garlic powder prepared by the present invention is prepared with comparative example 1 using conventional method Black garlic powder nutritional ingredient is roughly the same, and soluble sugar content and SOD activity are above fermented black garlic powder prepared by conventional method.
2. black garlic capsule prepared by couple embodiment 1-3 carries out the examination of dispersing uniformity, disintegration time limited and chronicity detection It tests, concrete outcome is shown in Table 2.
The detection method of dispersing uniformity:Capsule prepared by embodiment 1-3 is respectively taken 2, internal particle is placed in 20 In DEG C ± 1 DEG C of 100mL water, 3min is shaken, crosses No. 2 medicines sieves(National standard R40/3 series).
Disintegration time limited detection method:Capsule prepared by embodiment 1-3 is respectively taken 6, the water for being 37 DEG C ± 1 DEG C in temperature In, it is detected using lift disintegration of tablet instrument.
Chronicity detects:Place 36 months under conditions of 25 DEG C ± 2 DEG C of temperature, relative humidity 60% ± 10%, then into Row hygiene characteristic detects.
Table 2
From Table 2, it can be seen that black garlic capsules disperse uniformity prepared by the present invention is good, disintegration rate is very fast and can carry out Prolonged storage.
Clinical testing data
Existing 160 patients, there is constipation, insomnia, anaemia, calcium deficiency symptom, and immunity is low, male 60, age 45- 60 one full year of life, women 100, age are 30-45 one full year of life.
Usage and dosage:Patient is randomly divided into 4 groups of S1-S4, every group of 40 people, S1-S3 groups are taken embodiment 1-3 and prepared respectively Black garlic capsule, S4 groups take comparative example 2 preparation black garlic capsule, be three times per day, it is 3-4 each, 45 days for one treat Journey during medication, while assisting moderate exercise, wine for giving off smoking, dietary.
Curative effect judging standard:
Recovery from illness:Constipation, insomnia, Anemia disappear, and blood calcium maintains 2.18-2.63mmol/L.
Effectively:The symptom is mitigated, and blood calcium increases.
In vain:Every symptom has no significant change.
According to above-mentioned criterion, checked after a course for the treatment of, concrete outcome is shown in Table 3.
Table 3
The above embodiment is a preferred embodiment of the present invention, but embodiments of the present invention are not limited by embodiment System, other any changes made without departing from the spirit and principles of the present invention, modification, combination, replacement, simplification should be Equivalence replacement mode, is included within the scope of the present invention.

Claims (6)

1. a kind of black garlic capsule, which is characterized in that including following raw material:70-80 parts of fermented black garlic powder, black fungus powder 10-15 parts, 3-5 parts of tricalcium phosphate, 2-3 parts of microcrystalline cellulose, 2-3 parts of glycerin monostearate, 3-5 parts of cornstarch;
The fermented black garlic powder is that garlic is fermented after enzymolysis;
The fermented black garlic powder is prepared using following methods:
(1)After garlic peeling is cleaned, it is cut into garlic pieces, the papain for accounting for garlic weight 0.1% is then added, at 30-35 DEG C Under the conditions of, 2-3h is hydrolyzed, then heats to 80-85 DEG C, is fermented 3 days, then at 88-90 DEG C, fermentation 7-9 days can be to get Liquid state fermentation black garlic;
(2)Whey protein isolate is added in above-mentioned liquid state fermentation black garlic, particle is spray-dried to obtain after stirring evenly.
2. black garlic capsule according to claim 1, which is characterized in that including following raw material:80 parts of fermented black garlic powder, 12 parts of black fungus powder, 5 parts of tricalcium phosphate, 2 parts of microcrystalline cellulose, 3 parts of glycerin monostearate, 4 parts of cornstarch.
3. black garlic capsule according to claim 1, it is characterised in that:The thickness of the garlic pieces is 2-4mm.
4. black garlic capsule according to claim 1, it is characterised in that:The addition of the whey protein isolate is sent out for liquid The 0.5% of ferment black garlic weight.
5. black garlic capsule according to claim 4, it is characterised in that:The condition of the spray drying is:Inlet temperature 150 ~ 160 DEG C, 70 ~ 80 DEG C of outlet temperature, charging rate 50ml/min.
6. a kind of preparation method of the black garlic capsule as described in claim any one of 1-5, which is characterized in that include the following steps:
(1)It is 85- that 75% ethyl alcohol to solid content will be added in the parts by weight auricularia auriculajudae powder, the half of the cornstarch parts by weight 90%, stirring makes it be uniformly dispersed, and obtains mixed liquor;
(2)The parts by weight fermented black garlic powder, tricalcium phosphate, microcrystalline cellulose, glycerin monostearate, the other half corn is taken to form sediment Powder is uniformly mixed, and is sieved with 100 mesh sieve, with high-speed mixing granulating machine mixing granulation, is obtained particle;
(3)Mixed liquor is added in particle, continues stirring granulation, is filled into Capsules after gained particle drying, Every weight 0.5g.
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CN107149105A (en) * 2016-03-04 2017-09-12 北京圣伦食品有限公司 A kind of preparation method of instant black garlic powder
CN106491925A (en) * 2016-11-28 2017-03-15 徐州黎明食品有限公司 A kind of black garlic capsule and preparation method thereof
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CN1543848A (en) * 2003-11-27 2004-11-10 王永明 Garlic product
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CN103169041A (en) * 2011-12-21 2013-06-26 郑州固元堂医药科技有限公司 Fermented black garlic powder production method
CN103445104A (en) * 2013-01-05 2013-12-18 徐州绿之野生物食品有限公司 Black garlic capsules and preparation method thereof
CN104664384A (en) * 2015-03-10 2015-06-03 山东农业大学 Preparation method and application of black garlic fermentation liquid

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1437883A (en) * 2003-02-20 2003-08-27 刘安丽 Chewing tablet of edible tree fungi and calcium and making process
CN1543848A (en) * 2003-11-27 2004-11-10 王永明 Garlic product
CN101632484A (en) * 2008-07-27 2010-01-27 梁桂芳 Blackfungus decoction piece health nutrition food and preparation method thereof
CN103169041A (en) * 2011-12-21 2013-06-26 郑州固元堂医药科技有限公司 Fermented black garlic powder production method
CN103445104A (en) * 2013-01-05 2013-12-18 徐州绿之野生物食品有限公司 Black garlic capsules and preparation method thereof
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