CN105233297A - Traditional Chinese medicine taste improver and preparation method thereof - Google Patents
Traditional Chinese medicine taste improver and preparation method thereof Download PDFInfo
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- CN105233297A CN105233297A CN201510620097.0A CN201510620097A CN105233297A CN 105233297 A CN105233297 A CN 105233297A CN 201510620097 A CN201510620097 A CN 201510620097A CN 105233297 A CN105233297 A CN 105233297A
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Abstract
A traditional Chinese medicine taste improver is characterized in that effective ingredients include, by weight, 10-30 parts of sweet orange leaf, 10-18 parts of licorice root and 20-50 parts of yellow rice wine and also include, by weight, 5-10 parts of citric acid. A preparation method of the traditional Chinese medicine taste improver includes: soaking the sweet orange leaf and the licorice root in water for 20 min, boiling the water, keeping boiling until the volume of the water reduces to 2/5 of the original volume to form azeotropic liquid; cooling to 50 DEG C at the room temperature, adding the yellow rice wine, and performing stirring to obtain mixed liquid; filtering the mixed liquid to remove impurities, collecting filtrate, and adding a proper amount of citric acid. The invention has the advantages such as formula simplicity and good taste.
Description
Technical field
The invention belongs to oral pharmaceutic adjuvant technical field, be specifically related to a kind of Chinese medicine mouthfeel improving agent and preparation method.
Background technology
Along with the development of medical science, people for the understanding of Chinese medicine therapy system also in continuous intensification, especially for the traditional Chinese medical science in treatment of chronic diseases with regulate the advantage having doctor trained in Western medicine to reach in body constitution.But oral Chinese medicine, especially taking Chinese medicine decoction is then all nonvoluntary acceptance of a lot of people, because the mouthfeel of most of Chinese medicine decoction is also bad, there are the not acceptant taste stimulations such as bitter, puckery, raw meat, these stimulate the nausea and vomiting easily causing pill taker, have impact on carrying out smoothly for the treatment of, the particularly colony of the drug compliance such as child, old man difference.
Therefore, it is very necessary for developing a kind of preparation can improveing Chinese medicine decoction mouthfeel, but simple suppress another kind of taste with a kind of taste and usually can not obtain good effect.In addition, Chinese medicine ingredients is complicated, how when not affecting drug effect, improves its mouthfeel a great problem especially.
Summary of the invention
For prior art above shortcomings, the object of the present invention is to provide that a kind of formula is simple, the Chinese medicine mouthfeel improving agent of good mouthfeel and preparation method thereof.
To achieve these goals, the technical solution used in the present invention is as follows:
A kind of Chinese medicine mouthfeel improving agent, its effective ingredient comprises the yellow wine that mass fraction is the sweet Folium Citri tangerinae of 10 ~ 30 parts, 10 ~ 18 portions of Radix Glycyrrhizaes and 20 ~ 50 parts.
The citric acid of mass fraction 5 ~ 10 parts can also be comprised in effective ingredient.
Wherein, the preferred version of each effective ingredient to be mass fraction be sweet Folium Citri tangerinae, 15 parts of Radix Glycyrrhizaes, the yellow wine of 20 parts and the citric acids of 5 parts of 25 parts.
The preparation method of above-mentioned Chinese medicine mouthfeel improving agent, comprises the following steps:
1) be the sweet Folium Citri tangerinae of 10 ~ 30 parts by mass fraction, 10 ~ 18 portions of Radix Glycyrrhizaes immerse 20min in the water of 250 parts; Then boil, keep fluidized state, until the volume-diminished of water is original 2/5, form azeotropic liquid;
2) azeotropic liquid that step 1) is obtained is at room temperature cooled to 50 DEG C, adds the yellow wine of mass fraction 20 ~ 50 parts and stir 5min, form mixed liquor;
3) by step 2) obtained mixed liquor impurity screening, collect filtrate.
When necessary, an operating procedure can also be increased, namely
4) be that the citric acid of 5 ~ 10 parts joins in the filtrate that step 3) obtains by mass fraction.
Compared with prior art, the present invention has following beneficial effect:
1, restrained the Chinese medicine abnormal flavour allowing human body produce sense of discomfort by the not same-action of component, and do not affect drug effect.
2, the compliance of taking medicine of people is mentioned.
3, formula is simple, is easy to preparation, uses and large-scale production.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.
A kind of Chinese medicine mouthfeel improving agent, its effective ingredient comprises the yellow wine that mass fraction is the sweet Folium Citri tangerinae of 10 ~ 30 parts, 10 ~ 18 portions of Radix Glycyrrhizaes and 20 ~ 50 parts.
The citric acid of mass fraction 5 ~ 10 parts can also be comprised in effective ingredient.
Wherein, the preferred version of each effective ingredient to be mass fraction be sweet Folium Citri tangerinae, 15 parts of Radix Glycyrrhizaes, the yellow wine of 20 parts and the citric acids of 5 parts of 25 parts.
It has been generally acknowledged that the taste masking mechanism of Chinese medicine mainly comprises following three kinds: one is at present add correctives to make taste bud produce illusion; Two is avoided the taste factor directly to contact with taste bud; Three are reversible and temporarily benumb taste bud; Four is by drug competition taste receptor or block it and send corresponding Taste Signals to brain.
The mechanism of action of the present invention is: by the sweet Fructus Citri tangerinae element in sweet Folium Citri tangerinae as correctives, covered the bitterness in most of medical herbs with its sweet taste; The alcohol component contained in yellow wine then can react with the tannin producing astringent taste, and then generation insoluble substance, can be excreted by body metabolism, simultaneously, yellow wine also can assist the fishy smell removed in animal drugs, and yellow wine also helps the absorption of human body to medicine; The Main Function of Radix Glycyrrhizae is then the medicine be in harmonious proportion in above-mentioned substance and different prescription, identical with the conventional use in the traditional Chinese medical science.In addition, assign to select to add the amount of citric acid in visual decoction with or without the one-tenth of animal drugs, citric acid can neutralize with the fishy smell in animal drugs, and then removes its impact on decoction mouthfeel.The use of above-mentioned formula does not affect the original effect of Chinese medicine decoction, in also meeting completely, western compatibility rule.
Above-mentioned medicine all can be buied from market, and wherein citric acid should select crystal-type.
The preparation method of above-mentioned Chinese medicine mouthfeel improving agent, comprises the following steps:
1) be the sweet Folium Citri tangerinae of 10 ~ 30 parts by mass fraction, 10 ~ 18 portions of Radix Glycyrrhizaes immerse 20min in the water of 250 parts; Then boil, keep fluidized state, until the volume-diminished of water is original 2/5, form azeotropic liquid;
2) azeotropic liquid that step 1) is obtained is at room temperature cooled to 50 DEG C, adds the yellow wine of mass fraction 20 ~ 50 parts and stir 5min, form mixed liquor; If the too high meeting of temperature makes the effective ingredient of yellow wine volatilize, too low, then do not reach the interpenetrative object of the efficacy of a drug.
3) by step 2) obtained mixed liquor impurity screening, collect filtrate.
When necessary, namely for decoction in have an animal drugs time, an operating procedure can also be increased, namely
4) be that the citric acid of 5 ~ 10 parts joins in the filtrate that step 3) obtains by mass fraction.
embodiment one
Preparing effective ingredient is as follows the sweet Folium Citri tangerinae of mass fraction 25 parts, the Chinese medicine mouthfeel improving agent of 15 parts of Radix Glycyrrhizaes, the yellow wine of 20 parts and citric acids of 5 parts:
1) be the sweet Folium Citri tangerinae of 25 parts by mass fraction, 15 portions of Radix Glycyrrhizaes immerse 20min in the water of 250 parts; Then boil, keep fluidized state, until the volume-diminished of water is original 2/5, form azeotropic liquid.
2) azeotropic liquid that step 1) is obtained is at room temperature cooled to 50 DEG C, adds the yellow wine of mass fraction 20 parts and stir 5min, form mixed liquor;
3) by step 2) obtained mixed liquor impurity screening, collect filtrate.
4) be that the citric acid of 5 parts joins in the filtrate that step 3) obtains by mass fraction.
Add in " BAZHEN TANG " by this Chinese medicine mouthfeel improving agent, the people for 3 these decoctions of long-term taking takes.Using method is after being decocted by decoction, immediately by this Chinese medicine mouthfeel improving agent and decoction in mass ratio 1:10 mix, take when the temperature of the medicament after to be mixed drops to the suitable temperature taken, feedback is observed through 20 days, identical with drug effect when not using this Chinese medicine mouthfeel improving agent, but mouthfeel is obviously improved, without raw meat, astringent taste, pleasantly sweet.
embodiment two to four
Because of preparation and survey feedback method identical, be save length, only list different proportioning numbers as follows:
| Embodiment number | Sweet Folium Citri tangerinae/part | Radix Glycyrrhizae/part | Yellow wine/part | Citric acid/part | Respondent takes decoction title | Use natural law | Number |
| Two | 10 | 10 | 25 | 0 | Yupingfeng | 30 | 10 |
| Three | 30 | 18 | 30 | 10 | Radix Pulsatillae Decoction | 3 | 1 |
| Four | 15 | 12 | 50 | 7 | XIAOQINGLONG TANG | 10 | 10 |
Using method is identical with embodiment one, identical with drug effect when not using this Chinese medicine mouthfeel improving agent, but mouthfeel is obviously improved, without raw meat, astringent taste, pleasantly sweet.
The above embodiment of the present invention is only for example of the present invention is described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, other multi-form change and variations can also be made on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of amplifying out or variation be still in the row of protection scope of the present invention.
Claims (5)
1. a Chinese medicine mouthfeel improving agent, is characterized in that, its effective ingredient comprises the yellow wine that mass fraction is the sweet Folium Citri tangerinae of 10 ~ 30 parts, 10 ~ 18 portions of Radix Glycyrrhizaes and 20 ~ 50 parts.
2. Chinese medicine mouthfeel improving agent according to claim 1, is characterized in that, effective ingredient also comprises the citric acid of mass fraction 5 ~ 10 parts.
3. Chinese medicine mouthfeel improving agent according to claim 2, is characterized in that, effective ingredient to be mass fraction be sweet Folium Citri tangerinae, 15 parts of Radix Glycyrrhizaes, the yellow wine of 20 parts and the citric acids of 5 parts of 25 parts.
4. a preparation method for Chinese medicine mouthfeel improving agent, is characterized in that, comprises the following steps:
1) be the sweet Folium Citri tangerinae of 10 ~ 30 parts by mass fraction, 10 ~ 18 portions of Radix Glycyrrhizaes immerse 20min in the water of 250 parts; Then boil, keep fluidized state, until the volume-diminished of water is original 2/5, form azeotropic liquid;
2) azeotropic liquid that step 1) is obtained is at room temperature cooled to 50 DEG C, adds the yellow wine of mass fraction 20 ~ 50 parts and stir 5min, form mixed liquor;
3) by step 2) obtained mixed liquor impurity screening, collect filtrate.
5. the preparation method of Chinese medicine mouthfeel improving agent according to claim 4, is characterized in that, also comprise the steps:
4) be that the citric acid of 5 ~ 10 parts joins in the filtrate that step 3) obtains by mass fraction.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510620097.0A CN105233297A (en) | 2015-09-25 | 2015-09-25 | Traditional Chinese medicine taste improver and preparation method thereof |
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| CN201510620097.0A CN105233297A (en) | 2015-09-25 | 2015-09-25 | Traditional Chinese medicine taste improver and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109364208A (en) * | 2018-12-14 | 2019-02-22 | 隆昌晶牧康生物科技有限公司 | Enhance the auxotype Chinese herbal granules and preparation method thereof of livestock and poultry disease resistance |
-
2015
- 2015-09-25 CN CN201510620097.0A patent/CN105233297A/en active Pending
Non-Patent Citations (4)
| Title |
|---|
| 国家药典委员会: "《中华人民共和国药典-2010年版 二部》", 31 January 2010 * |
| 李学林等: ""中药汤剂掩味技术探讨"", 《中医研究》 * |
| 李晨晨等: ""酒的功用及发展历史"", 《中国实验方剂学杂志》 * |
| 陈焕旭等: ""中药汤剂使用依从性现状及提高方法"", 《实用中医内科杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109364208A (en) * | 2018-12-14 | 2019-02-22 | 隆昌晶牧康生物科技有限公司 | Enhance the auxotype Chinese herbal granules and preparation method thereof of livestock and poultry disease resistance |
| CN109364208B (en) * | 2018-12-14 | 2021-08-17 | 隆昌晶牧康生物科技有限公司 | Nutritional traditional Chinese medicine granules for enhancing disease resistance of livestock and poultry and preparation method thereof |
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Application publication date: 20160113 |
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