CN104971325A - Spleen reinforcing and stomach harmonizing traditional Chinese medicinal composition and preparation method thereof - Google Patents
Spleen reinforcing and stomach harmonizing traditional Chinese medicinal composition and preparation method thereof Download PDFInfo
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- CN104971325A CN104971325A CN201510335302.9A CN201510335302A CN104971325A CN 104971325 A CN104971325 A CN 104971325A CN 201510335302 A CN201510335302 A CN 201510335302A CN 104971325 A CN104971325 A CN 104971325A
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Abstract
The invention discloses a spleen reinforcing and stomach harmonizing traditional Chinese medicinal composition. The composition is prepared from, by weight, 10-15 parts of Radix Codonopsis, 7-12 parts of white hyacinth bean, 7-12 parts of dried orange peel, 7-12 parts of Cortex Magnoliae Officinalis, 4-8 parts of hawthorn fruit, 1-5 parts of ginger, 1-5 parts of jujube and 1-5 parts of honey-fried licorice root. The invention also provides a preparation method of the composition. Above raw medicines in the above formula are combined to realize qi tonifying, spleen reinforcing, dampness drying, spleen activating, qi moving and stomach harmonizing efficacies; the composition is an elite medicine used for treating periodic uncomfortable state of stomach and prepared from pure-natural high-quality medicinal and edible traditional Chinese medicinal materials through a modern production technology, is suitable for people of all ages in all seasons, and is an essential product at home; and Radix Codonopsis stir-baked with rice and the white hyacinth bean are added in an ultrafine powder form as a preparation auxiliary material and a monarch medicine in the composition.
Description
Technical field
The present invention relates to Chinese medicine composition field, be specifically related to Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach and preparation method thereof.
Background technology
By the impact of the factors such as operating pressure increase and Bad Eating Habit, the sickness rate of gastrointestinal disease has the trend raised year by year.The treatment of current doctor trained in Western medicine to various old gastropathy fails to obtain satisfactory effect, and after the side effect in addition caused by life-time service, drug resistance and drug withdrawal, the shortcoming such as easy recurrence, causes its application to receive certain restriction.
Chinese traditional treatment weakness of the spleen and stomach, the spleen and stomach being stranded by dampness, taste are become estranged, distension and fullness in the abdomen, anorexia, tastelessness, and vomiting is felt sick, belch acid regurgitation, and limbs are heavy waits disease to have significant advantage.
Summary of the invention
Object of the present invention is exactly for above-mentioned defect of the prior art, provides Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach and preparation method thereof.
To achieve these goals, technical scheme provided by the invention is: a kind of Chinese medicine composition of invigorating the spleen and regulating the stomach, is to be prepared by the following raw material of Chinese medicine according to parts by weight: Radix Codonopsis 10-15 part, Semen Lablab Album 7-12 part, Pericarpium Citri Reticulatae 7-12 part, Cortex Magnoliae Officinalis 7-12 part, Fructus Crataegi 4-8 part, Rhizoma Zingiberis Recens 1-5 part, Fructus Jujubae 1-5 part, Radix Glycyrrhizae Preparata 1-5 part.
Further, the Chinese medicine composition of above-mentioned a kind of invigorating the spleen and regulating the stomach is prepared by the following raw material of Chinese medicine according to parts by weight: Radix Codonopsis 12 parts, Semen Lablab Album 9 parts, Pericarpium Citri Reticulatae 9 parts, Cortex Magnoliae Officinalis 9 parts, Fructus Crataegi 6 parts, 3 parts, Rhizoma Zingiberis Recens, 3 parts, Fructus Jujubae, Radix Glycyrrhizae Preparata 3 parts.
Further, the Chinese medicine composition of above-mentioned a kind of invigorating the spleen and regulating the stomach, the concocting method of described Radix Codonopsis is that rice is fried.
Second object of the present invention there is provided the preparation method of the Chinese medicine composition of above-mentioned a kind of invigorating the spleen and regulating the stomach, comprises the following steps:
1) by raw material of Chinese medicine Radix Codonopsis after rice is fried and is concocted, carry out micronizing with Semen Lablab Album, after pulverizing, cross 700 mesh sieves, then by Radix Codonopsis superfine powder and Semen Lablab Album superfine powder according to proportional quantity mix homogeneously, obtain mixed powder;
2) raw material of Chinese medicine Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Fructus Crataegi, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Glycyrrhizae Preparata is taken according to proportional quantity, the concentration adding above-mentioned medical material gross weight 5 times amount is the alcoholic solution of 50-90%, soak 6-10 hour, stirred every 1 hour 1 time, seepage pressure effects is carried out again with the alcoholic solution of 12-30 times amount same concentrations, percolation flow velocity is 1.0-3.0mL/min, obtains extracting solution;
3) by step 2) extracting solution that obtains is at temperature 45-60 DEG C, and concentrated on Rotary Evaporators, rotary speed 200rpm, obtains Chinese medicine ethanol extraction concentrated solution, and concentration ratio is 8-20;
4) by step 3) the Chinese medicine ethanol extraction concentrated solution that obtains carries out spraying dry, and obtain Powdered extractum, in described Powdered extractum, the content of Pericarpium Citri Reticulatae glycosides is 0.52-2.54mg/g, and the content of magnolol is 0.18-1.60mg/g;
5) by step 1) mixed powder and the step 4 that obtain) the Powdered extractum that obtains mixes, and mixes 10-15 minute to the Chinese medicine composition that evenly can obtain a kind of invigorating the spleen and regulating the stomach.
Further, the preparation method of the Chinese medicine composition of above-mentioned a kind of invigorating the spleen and regulating the stomach, described step 2) in, the addition of alcoholic solution is 20 times of medical material gross weight; Ethanol solution concentration is 70%; Soak time is 8 hours; Percolation flow velocity is 2.0mL/min.
Beneficial effect of the present invention is: Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach provided by the invention and preparation method thereof, and reusing Radix Codonopsis replenishing QI to invigorate the spleen in compositions is monarch drug; Semen Lablab Album, Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis removing dampness dampness, activating the spleen are except being completely ministerial drug; Hawthorn digesting stomach invigorating, circulation of qi promoting dissipating blood stasis are adjuvant drug; Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Glycyrrhizae Preparata conciliate taste, coordinating the actions of various ingredients in a prescription for making medicine.All medicines share and gather the merit of replenishing QI to invigorate the spleen, dampness activating the spleen, relieving QI stagnancy in the stomach altogether; Be a kind of with natural quality integration of edible and medicinal herbs Chinese crude drug for raw material, the elite medicine for stomach periodically indisposition being aided with that modern production process refines, all-ages, suitable for four seasons, be the good merchantable brand of herbal; Stir-baked RADIX CONDONOPSIS PILOSULAE in rice wherein and Semen Lablab Album are directly used as medicine with superfine powder, serve as preparation adjuvant on the one hand, are again the monarch drug in compositions on the other hand.
Detailed description of the invention
Embodiment 1:
A preparation method for the Chinese medicine composition of invigorating the spleen and regulating the stomach, comprises the following steps:
1) raw material of Chinese medicine Radix Codonopsis is fried after the process of preparing Chinese medicine through rice, carry out micronizing with Semen Lablab Album, cross 700 mesh sieves after pulverizing, then by Radix Codonopsis superfine powder 10kg and Semen Lablab Album superfine powder 7kg mix homogeneously, obtain mixed powder;
2) raw material of Chinese medicine Pericarpium Citri Reticulatae 7kg, Cortex Magnoliae Officinalis 7kg, Fructus Crataegi 4kg, Rhizoma Zingiberis Recens 1kg, Fructus Jujubae 1kg, Radix Glycyrrhizae Preparata 1kg is taken, the concentration adding above-mentioned medical material gross weight 5 times amount is the alcoholic solution of 50%, soak 6 hours, stirred every 1 hour 1 time, seepage pressure effects is carried out again with the alcoholic solution of 12 times amount same concentrations, percolation flow velocity is 1.0mL/min, obtains extracting solution;
3) by step 2) extracting solution that obtains is under temperature 45 C, and concentrated on Rotary Evaporators, rotary speed 200rpm, obtains Chinese medicine ethanol extraction concentrated solution, and concentration ratio is 8;
4) by step 3) the Chinese medicine ethanol extraction concentrated solution that obtains carries out spraying dry, and obtain Powdered extractum, in described Powdered extractum, the content of Pericarpium Citri Reticulatae glycosides is 0.52mg/g, and the content of magnolol is 0.18mg/g;
5) by step 1) mixed powder and the step 4 that obtain) the Powdered extractum that obtains mixes, and mixes 10 minutes to the Chinese medicine composition that evenly can obtain a kind of invigorating the spleen and regulating the stomach.
Embodiment 2:
A preparation method for the Chinese medicine composition of invigorating the spleen and regulating the stomach, comprises the following steps:
1) raw material of Chinese medicine Radix Codonopsis is fried after the process of preparing Chinese medicine through rice, carry out micronizing with Semen Lablab Album, cross 700 mesh sieves after pulverizing, then by Radix Codonopsis superfine powder 15kg and Semen Lablab Album superfine powder 12kg mix homogeneously, obtain mixed powder;
2) raw material of Chinese medicine Pericarpium Citri Reticulatae 12kg, Cortex Magnoliae Officinalis 12kg, Fructus Crataegi 8kg, Rhizoma Zingiberis Recens 5kg, Fructus Jujubae 5kg, Radix Glycyrrhizae Preparata 5kg is taken, the concentration adding above-mentioned medical material gross weight 5 times amount is the alcoholic solution of 90%, soak 10 hours, stirred every 1 hour 1 time, seepage pressure effects is carried out again with the alcoholic solution of 30 times amount same concentrations, percolation flow velocity is 3.0mL/min, obtains extracting solution;
3) by step 2) extracting solution that obtains is under temperature 60 C, and concentrated on Rotary Evaporators, rotary speed 200rpm, obtains Chinese medicine ethanol extraction concentrated solution, and concentration ratio is 15;
4) by step 3) the Chinese medicine ethanol extraction concentrated solution that obtains carries out spraying dry, and obtain Powdered extractum, in described Powdered extractum, the content of Pericarpium Citri Reticulatae glycosides is 1.04mg/g, and the content of magnolol is 0.49mg/g;
5) by step 1) mixed powder and the step 4 that obtain) the Powdered extractum that obtains mixes, and mixes 10-15 minute to the Chinese medicine composition that evenly can obtain a kind of invigorating the spleen and regulating the stomach.
Embodiment 3:
A preparation method for the Chinese medicine composition of invigorating the spleen and regulating the stomach, comprises the following steps:
1) raw material of Chinese medicine Radix Codonopsis is fried after the process of preparing Chinese medicine through rice, carry out micronizing with Semen Lablab Album, cross 700 mesh sieves after pulverizing, then by Radix Codonopsis superfine powder 12kg and Semen Lablab Album superfine powder 9kg mix homogeneously, obtain mixed powder;
2) raw material of Chinese medicine Pericarpium Citri Reticulatae 9kg, Cortex Magnoliae Officinalis 9kg, Fructus Crataegi 6kg, Rhizoma Zingiberis Recens 3kg, Fructus Jujubae 3kg, Radix Glycyrrhizae Preparata 3kg is taken, the concentration adding above-mentioned medical material gross weight 5 times amount is the alcoholic solution of 70%, soak 8 hours, stirred every 1 hour 1 time, seepage pressure effects is carried out again with the alcoholic solution of 20 times amount same concentrations, percolation flow velocity is 2.0mL/min, obtains extracting solution;
3) by step 2) extracting solution that obtains is under temperature 50 C, and concentrated on Rotary Evaporators, rotary speed 200rpm, obtains Chinese medicine ethanol extraction concentrated solution, and concentration ratio is 10;
4) by step 3) the Chinese medicine ethanol extraction concentrated solution that obtains carries out spraying dry, and obtain Powdered extractum, in described Powdered extractum, the content of Pericarpium Citri Reticulatae glycosides is 1.15mg/g, and the content of magnolol is 0.44mg/g;
5) by step 1) mixed powder and the step 4 that obtain) the Powdered extractum that obtains mixes, and mixes 10-15 minute to the Chinese medicine composition that evenly can obtain a kind of invigorating the spleen and regulating the stomach.
Embodiment 4:
Get Pericarpium Citri Reticulatae 9 parts, Cortex Magnoliae Officinalis 9 parts, Fructus Crataegi 6 parts, 3 parts, Rhizoma Zingiberis Recens, 3 parts, Fructus Jujubae, Radix Glycyrrhizae Preparata 3 parts, by table 1 factor level table design orthogonal extraction technique, add the alcoholic solution being equivalent to above-mentioned medical material weight 5 times amount, concentration of alcohol 50-90%, soak 8 hours, stirred every 1 hour 1 time, seepage pressure effects is carried out again with the alcoholic solution of 12-30 times amount same concentrations, extraction flow speed control is 1.0-3.0mL/min, extracting solution after extraction is at 50 DEG C of temperature, concentrated on Rotary Evaporators, rotary speed 200rpm, obtain said components ethanol extraction concentrated solution, cocnentration factor 6, carry out spraying dry again, obtain Powdered extractum, with Pericarpium Citri Reticulatae glycosides in extractum, content and the obtained extractum amount of magnolol are index, carry out the preferred of extraction process.
Table 1
Extraction process L9 (3
4) orthogonal design table preferred result is as shown in table 2, is extraction process L9 (3
4) orthogonal design table.
Table 2
The intuitive analysis of average paste-forming rate, as can be seen from Table 2, in selected 3 factors, to paste-forming rate have the greatest impact for extraction time A (amount of alcohol added), 3 factors are A>B>C to the influence degree of paste-forming rate successively.Best of breed is A
2b
2c
3.
The intuitive analysis of Pericarpium Citri Reticulatae glycosides content, as can be seen from Table 2, to Pericarpium Citri Reticulatae glycosides content have the greatest impact for concentration of alcohol C, the influence degree of 3 factors to Pericarpium Citri Reticulatae glycosides content is C>A>B successively.Best of breed is A
1b
2c
2.
The intuitive analysis of Determination of Magnolol, as can be seen from Table 2, in selected 3 factors, to the content of magnolol that have the greatest impact is concentration of alcohol C, 3 factors are C>A>B to the influence degree of the content of magnolol successively.Best of breed is A
1b
2c
2.
The intuitive analysis of Hesperidin honokiol content shows that best of breed is all A
1b
2c
2.
Comprehensive analysis, the present invention selects optimised process to be A
2b
2c
2.Namely add the alcoholic solution being equivalent to above-mentioned medical material weight 20 times amount, concentration of alcohol 700%, soak 8 hours, stirred every 1 hour 1 time, carry out seepage pressure effects, extraction flow speed control is 2.0mL/min, extracting solution after extraction is at 50 DEG C of temperature, concentrated on Rotary Evaporators, rotary speed 200rpm, obtains said components ethanol extraction concentrated solution, cocnentration factor 10, carry out spraying dry again, obtain Powdered extractum, for the preparation of preparation.
Last it is noted that the foregoing is only the preferred embodiments of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (5)
1. the Chinese medicine composition of an invigorating the spleen and regulating the stomach, it is characterized in that, be prepared by the following raw material of Chinese medicine according to parts by weight: Radix Codonopsis 10-15 part, Semen Lablab Album 7-12 part, Pericarpium Citri Reticulatae 7-12 part, Cortex Magnoliae Officinalis 7-12 part, Fructus Crataegi 4-8 part, Rhizoma Zingiberis Recens 1-5 part, Fructus Jujubae 1-5 part, Radix Glycyrrhizae Preparata 1-5 part.
2. the Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach according to claim 1, it is characterized in that, be prepared by the following raw material of Chinese medicine according to parts by weight: Radix Codonopsis 12 parts, Semen Lablab Album 9 parts, Pericarpium Citri Reticulatae 9 parts, Cortex Magnoliae Officinalis 9 parts, Fructus Crataegi 6 parts, 3 parts, Rhizoma Zingiberis Recens, 3 parts, Fructus Jujubae, Radix Glycyrrhizae Preparata 3 parts.
3. the Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach according to claim 1 and 2, is characterized in that, the concocting method of described Radix Codonopsis is that rice is fried.
4. the preparation method of the Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach according to claim 3, is characterized in that, comprise the following steps:
1) by raw material of Chinese medicine Radix Codonopsis after rice is fried and is concocted, carry out micronizing with Semen Lablab Album, after pulverizing, cross 700 mesh sieves, then by Radix Codonopsis superfine powder and Semen Lablab Album superfine powder according to proportional quantity mix homogeneously, obtain mixed powder;
2) raw material of Chinese medicine Pericarpium Citri Reticulatae, Cortex Magnoliae Officinalis, Fructus Crataegi, Rhizoma Zingiberis Recens, Fructus Jujubae, Radix Glycyrrhizae Preparata is taken according to proportional quantity, the concentration adding above-mentioned medical material gross weight 5 times amount is the alcoholic solution of 50-90%, soak 6-10 hour, stirred every 1 hour 1 time, seepage pressure effects is carried out again with the alcoholic solution of 12-30 times amount same concentrations, percolation flow velocity is 1.0-3.0 mL/min, obtains extracting solution;
3) by step 2) extracting solution that obtains is at temperature 45-60 DEG C, and concentrated on Rotary Evaporators, rotary speed 200rpm, obtains Chinese medicine ethanol extraction concentrated solution, and concentration ratio is 8-20;
4) Chinese medicine ethanol extraction concentrated solution step 3) obtained carries out spraying dry, obtains Powdered extractum, and in described Powdered extractum, the content of Pericarpium Citri Reticulatae glycosides is 0.52-2.54mg/g, and the content of magnolol is 0.18-1.60mg/g;
5) the Powdered extractum that mixed powder step 1) obtained and step 4) obtain mixes, and mixes 10-15 minute to the Chinese medicine composition that evenly can obtain a kind of invigorating the spleen and regulating the stomach.
5. the preparation method of the Chinese medicine composition of a kind of invigorating the spleen and regulating the stomach according to claim 4, is characterized in that, described step 2) in, the addition of alcoholic solution is 20 times of medical material gross weight; Ethanol solution concentration is 70%; Soak time is 8 hours; Percolation flow velocity is 2.0mL/min.
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CN105597012A (en) * | 2016-02-03 | 2016-05-25 | 河南省南山菇业有限公司 | Traditional Chinese medicine composition for nourishing spleen and enriching stomach and preparation method of traditional Chinese medicine composition |
CN105999028A (en) * | 2016-06-14 | 2016-10-12 | 周军怀 | Traditional Chinese medicine composition with effects of strengthening spleen and harmonizing stomach and preparation thereof |
CN106942735A (en) * | 2017-04-02 | 2017-07-14 | 代光玉 | The diet therapy formula that salubrity invigorating the spleen is replenished the calcium |
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CN102284041A (en) * | 2010-06-17 | 2011-12-21 | 苏州知微堂生物科技有限公司 | Preparation technology and production method of integrated novel Pingwei powder dosage form |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105597012A (en) * | 2016-02-03 | 2016-05-25 | 河南省南山菇业有限公司 | Traditional Chinese medicine composition for nourishing spleen and enriching stomach and preparation method of traditional Chinese medicine composition |
CN105999028A (en) * | 2016-06-14 | 2016-10-12 | 周军怀 | Traditional Chinese medicine composition with effects of strengthening spleen and harmonizing stomach and preparation thereof |
CN105999028B (en) * | 2016-06-14 | 2020-02-14 | 周军怀 | Traditional Chinese medicine composition for strengthening spleen and stomach and preparation thereof |
CN106942735A (en) * | 2017-04-02 | 2017-07-14 | 代光玉 | The diet therapy formula that salubrity invigorating the spleen is replenished the calcium |
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