CN105233271B - A kind of anti-scar salamander collagen burn cream and preparation method thereof - Google Patents
A kind of anti-scar salamander collagen burn cream and preparation method thereof Download PDFInfo
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- CN105233271B CN105233271B CN201510798413.3A CN201510798413A CN105233271B CN 105233271 B CN105233271 B CN 105233271B CN 201510798413 A CN201510798413 A CN 201510798413A CN 105233271 B CN105233271 B CN 105233271B
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Abstract
A kind of anti-scar salamander collagen burn cream and preparation method thereof, is related to a kind of burn cream, first takes each raw material by following raw material proportionings：5 ~ 15g of salamander collagen, 5 ~ 15ml of giant salamander salamander oil, 35 ~ 45ml of sesame oil, 3 ~ 5g of 10 ~ 20g of beeswax, three 30 ~ 40g of Huang and borneol, described three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition；By three is yellow and borneol be ground into it is powdered, it is spare；Beeswax is melted first, sesame oil and three blooms are then added, after 15~20min of tanning is mixed at 100 105 DEG C, filtering takes liquid；It waits for that fluid temperature is cooled to room temperature, giant salamander salamander oil and borneol powder is added, is subsequently placed at a temperature of 4 10 DEG C；Salamander collagen is added when fluid temperature drops to 4 10 DEG C, stirs and evenly mixs, finally plus vaseline is modulated into the ointment of certain stickiness to get product.The burn cream of the present invention can promote the quick healing of empyrosis wound surface, improve the recovery effects of empyrosis wound surface skin, prevent from staying scar.
Description
Technical field
The present invention relates to a kind of burn cream and preparation method thereof, and in particular to a kind of anti-scar salamander collagen burn cream and
Preparation method.
Background technology
According to statistics, every year because in the death toll of unexpected injury, burn is only second to traffic accident, comes second in China,
And also there are a large amount of wounded to be burnt in traffic accident injury.Improperly processing often leads to patient's scar to burn, burns
Scar trace not only damages appearance, can also influence the physiological function of linked groups or organ, if burn wound influences feed at mouth,
It affects vision outside eye or eyelid, breathing etc. is influenced near nostril.So dispelling burn wound as early as possible just can guarantee our health
Life.Some present hospitals have the relevant method for eliminating scar, but are realized by the scar operation of dispelling of some clinical repairs,
It is more complicated and costly, so the best way timely medication after still scalding, carries out strick precaution from initially, prevents from staying
Scar.
Existing ointment for treating burn ingredient is all mainly some animal oil, Chinese medicine etc., can only play disinfecting detoxifying, promoting blood circulationization
It becomes silted up, remove necrosis and promote granulation, hemostasis and pain-relieving and other effects, can not but help to repair skin, prevent from staying scar.Based on this, the present invention provides one
Anti- scar salamander collagen burn cream of kind and preparation method thereof.
Invention content
The object of the present invention is to provide a kind of anti-scar salamander collagen burn cream and preparation method thereof, to promote burn and scald
The quick healing of the surface of a wound improves the recovery effects of empyrosis wound surface skin, prevents from staying scar.
To achieve the above object, the technical scheme is that：A kind of anti-scar salamander collagen burn cream, is under
State 5 ~ 15g of salamander collagen of raw material proportioning, 5 ~ 15ml of giant salamander salamander oil, 35 ~ 45ml of sesame oil, 10 ~ 20g of beeswax, three Huangs 30 ~
40g and 3 ~ 5g of borneol and it is additional by above-mentioned raw materials be modulated into the vaseline with certain stickiness ointment composition；Described
Three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition.Wherein, by above-mentioned raw materials match, required vaseline be 10 ~
15g。
A kind of preparation method of anti-scar salamander collagen burn cream, includes the following steps：
（1）, by above-mentioned raw materials proportioning take each raw material, by three is yellow and borneol be ground into it is powdered, it is spare；
（2）, beeswax melted, be then added sesame oil and three blooms, at 100-105 DEG C after 15~20min of mixing tanning,
Filtering, takes liquid；
（3）, wait for that fluid temperature is cooled to room temperature, giant salamander salamander oil and borneol powder is added, is subsequently placed at a temperature of 4-10 DEG C；
（4）, salamander collagen is added when fluid temperature drops to 4-10 DEG C, stir and evenly mix, finally plus vaseline tune
The ointment of certain stickiness is made to get product.
Normal skin has protection blocking to the ultraviolet light in nature, deep skin cell is protected to hinder from ultraviolet light
Harmful effect, and the deep skin cell of burnt degree is exposed to outside, is easily infected under ultraviolet irradiation.The present invention burns
Giant salamander salamander collagen in cream can absorb ultraviolet light, make to be exposed at empyrosis wound surface outer deep skin cell from
The injury of ultraviolet light reduces trauma surface infestation, promotes wound healing.In addition, through analyzing it is found that salamander collagen includes a variety of people
Body essential amino acid, this is more advantageous to the healing for promoting burn and scald mouth.
Giant salamander salamander oil component can inhibit the nitric oxide production generation of wound tissue, to reduce wound inflammation cell factor
Release, and bacteriostatic activity is played, participation and wound healing.
Vaseline can form one of protective film in skin surface, so that the moisture of skin is not easy to evaporate lost, block and come from
Bacterium in air and skin contact, to reduce the possibility of infection.And it is largely insoluble in water, can be attached to skin for a long time
On skin, therefore there is good moistening effect, so that the skin histology of wound location is kept optimum state, accelerate repairing for skin itself
Reactivation power.
Advantageous effect：
The burn cream of the present invention has wound healing fast compared with existing burn medicine in the market（7 days or so）, do not stay scar
The special efficacy of trace.
The burn cream of the present invention has refrigerant paralysis to act on wound, can reduce the pain of patient.
The burn cream of the present invention can make the skin for scalding burn wound recovery keep smooth, enhance skin elasticity, prevent skin
Skin is dried, and has skin care effect concurrently.
The burn cream of the present invention is using salamander collagen as primary raw material, with giant salamander oil, sesame oil, borneol, vaseline, three
Yellow and beeswax Chinese medicine material mixing is allocated, all raw materials be all it is pure natural, it is without side-effects to skin.
The burn cream of the present invention is suitable for skin scald, fire victim, especially to once to superficial second degree burn, scald effect
More preferably.
Specific implementation mode
The formula of following four embodiment of the present invention is prepared according to previously described preparation method.
Embodiment 1
A kind of anti-scar salamander collagen burn cream, is by the salamander collagen 5g of following raw material proportionings, giant salamander salamander
Oily 10ml, sesame oil 35ml, beeswax 20g, three Huang 30g and borneol 5g and additional be modulated into above-mentioned raw materials have centainly
The vaseline of stickiness ointment forms；Three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition, it is additional
Vaseline is 10g.
Embodiment 2
A kind of anti-scar salamander collagen burn cream, is by the salamander collagen 10g of following raw material proportionings, giant salamander salamander
Oily 10ml, sesame oil 40ml, beeswax 15g, three Huang 35g and borneol 3.9g and additional above-mentioned raw materials are modulated into one
Determine the vaseline composition of stickiness ointment；Three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition, it is additional
Vaseline be 12g.
Embodiment 3
A kind of anti-scar salamander collagen burn cream, is by the salamander collagen 15g of following raw material proportionings, giant salamander salamander
Oily 5ml, sesame oil 45ml, beeswax 10g, three Huang 35g and borneol 3g and additional be modulated into above-mentioned raw materials stick with certain
The vaseline of consistency ointment forms；Three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition, additional is all
Intellectual circle is 15g.
Embodiment 4
A kind of anti-scar salamander collagen burn cream, is by the salamander collagen 10g of following raw material proportionings, giant salamander salamander
Oily 5ml, sesame oil 35ml, beeswax 10g, three Huang 40g and borneol 4g and additional be modulated into above-mentioned raw materials stick with certain
The vaseline of consistency ointment forms；Three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition, additional is all
Intellectual circle is 12g.
Pharmacological property is tested
Using rat as experimental animal, superficial second degree burn is formed on rat skin surface, surface of a wound area is 0.7cm2。
Medication：Burn injury in rats position clear water is rinsed into 1--2min, then is disinfected in alcohol, takes appropriate ointment later
It is uniformly applied to the position of burn injury in rats, covers entire injury（Thickness is thinner than 1mm）, pay attention to wound health.Every
12h replaces new drug, before each dressing, must wipe the drug remained on the surface of a wound and liquefied substance away, and disinfect in alcohol, lasting to use
Medicine is until restore.
Experimental group：Ointment using the present invention is administered treatment, time by above-mentioned medication to burn injury in rats position
It was limited with 7 days, record every other day is measured to the surface of a wound size at burn injury in rats position.
Control group：Using burn cream common on the market, burn injury in rats position is administered by above-mentioned medication and is controlled
It treats, the time was limited with 7 days, every other day measured record to the surface of a wound size at burn injury in rats position.
Experimental result：
As a result it shows：Experimental group anti-scar salamander collagen burn cream using the present invention to the burn injury in rats surface of a wound carry out to
Medicine is treated, and the 7th day surface of a wound of administration can fully recover, and not have scar.
Control group is treated using existing general burn cream on the market, and the area of the 7th day rat burn wound is administered
For 0.2 cm2, there is no fully recover；Control group is fully recovered after continuing administration 3 days using general burn cream, and a 0.5mm is left after recovery from illness
Long scar protuberance.
Claims (2)
1. a kind of anti-scar salamander collagen burn cream, it is characterised in that：By following raw material proportionings salamander collagen 5 ~
15g, 5 ~ 15ml of giant salamander salamander oil, 35 ~ 45ml of sesame oil, 10 ~ 20g of beeswax, three 30 ~ 40g of Huang, 3 ~ 5g of borneol and vaseline composition；
Three Huangs are 1 by weight ratio:1:1 coptis, Cortex Phellodendri and rheum officinale composition；Wherein, required vaseline is 10 ~ 15g.
2. a kind of preparation method of anti-scar salamander collagen burn cream as described in claim 1, it is characterised in that：Including such as
Lower step：
（1）, by above-mentioned raw materials proportioning take each raw material, by three is yellow and borneol be ground into it is powdered, it is spare；
（2）, beeswax melted, be then added sesame oil and three blooms, at 100-105 DEG C after 15~20min of mixing tanning, mistake
Filter, takes liquid；
（3）, wait for that fluid temperature is cooled to room temperature, giant salamander salamander oil and borneol powder is added, is subsequently placed at a temperature of 4-10 DEG C；
（4）, when fluid temperature drops to 4-10 DEG C be added salamander collagen, stir and evenly mix, finally plus vaseline be modulated into
Ointment is to get product.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510798413.3A CN105233271B (en) | 2015-11-19 | 2015-11-19 | A kind of anti-scar salamander collagen burn cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510798413.3A CN105233271B (en) | 2015-11-19 | 2015-11-19 | A kind of anti-scar salamander collagen burn cream and preparation method thereof |
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| Publication Number | Publication Date |
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| CN105233271A CN105233271A (en) | 2016-01-13 |
| CN105233271B true CN105233271B (en) | 2018-08-31 |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105999213A (en) * | 2016-06-15 | 2016-10-12 | 通江县光泰科技发展有限责任公司 | Preparation method of giant salamander skin ointment for repairing human skin |
| CN109646513A (en) * | 2019-02-28 | 2019-04-19 | 都江堰同兴金色池塘大鲵养殖有限责任公司 | A kind of Chinese medicine composition and preparation method thereof for treating burn and scald |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101254246A (en) * | 2008-04-03 | 2008-09-03 | 华中科技大学 | External-used burn and scald treating medicine and its preparation |
| CN101648014A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating skin injury and ulcer and application thereof |
| CN102335288A (en) * | 2010-07-20 | 2012-02-01 | 陕西理工学院 | Giant salamander skin mucus scalding ointment |
| CN105018555A (en) * | 2015-08-06 | 2015-11-04 | 重庆馗丰食品有限公司 | Preparation method of giant salamander skin collagen peptide |
-
2015
- 2015-11-19 CN CN201510798413.3A patent/CN105233271B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101254246A (en) * | 2008-04-03 | 2008-09-03 | 华中科技大学 | External-used burn and scald treating medicine and its preparation |
| CN101648014A (en) * | 2008-08-13 | 2010-02-17 | 北京和润创新医药科技发展有限公司 | Medicinal composition for treating skin injury and ulcer and application thereof |
| CN102335288A (en) * | 2010-07-20 | 2012-02-01 | 陕西理工学院 | Giant salamander skin mucus scalding ointment |
| CN105018555A (en) * | 2015-08-06 | 2015-11-04 | 重庆馗丰食品有限公司 | Preparation method of giant salamander skin collagen peptide |
Non-Patent Citations (1)
| Title |
|---|
| 大鲵不同部位制备物治疗烫伤及冻伤作用研究;万军梅;《医药导报》;20130531;第32卷(第5期);第603-604页 * |
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| CN105233271A (en) | 2016-01-13 |
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Effective date of registration: 20230522 Address after: 2nd Floor, Hongchu Technology Building, No. 18 Chuncheng Road, High tech Zone, Luoyang Area, China (Henan) Free Trade Pilot Zone, Luoyang City, Henan Province, 471000 Patentee after: LUOYANG BAKU BIO-TECH Co.,Ltd. Address before: No.71, Luolong Road, Luolong District, Luoyang City, Henan Province Patentee before: LUOYANG NORMAL University |
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