CN105233128A - Medicine treating gastric ulcers and preparation method thereof - Google Patents
Medicine treating gastric ulcers and preparation method thereof Download PDFInfo
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- CN105233128A CN105233128A CN201510814621.8A CN201510814621A CN105233128A CN 105233128 A CN105233128 A CN 105233128A CN 201510814621 A CN201510814621 A CN 201510814621A CN 105233128 A CN105233128 A CN 105233128A
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Abstract
The invention discloses medicine treating gastric ulcers and a preparation method thereof and belongs to the field of traditional Chinese medicine. The medicine is prepared from theezan tea, pot-burnt soy milk, tartary buckwheat roots, cryptolepis sinensis, peppers, randia cochinchinensis, swallowtail caterpillar, alpinia japonica, delavay greenleaf elaeagnus leaves, buckbeans, dotted ardisia, jasmine, dendrobium lindleyi, roses, silverweed cinquefoil roots and lushan mountain barberry. The medicine is proper in medicine compatibility, accords with theories of traditional Chinese medicine and pharmacology and modern medicine and pharmacology, has the effects of promoting qi circulation to relieve pain, nourishing yin and the stomach, reinforcing qi and nourishing blood and expelling wind and cold pathogens, has a unique treatment effect on treating gastric ulcers, is remarkable in treatment effect, good in stability, low in cost, convenient to take and free of toxic and side effects, treats both symptoms and root causes and is worthy of wide application and popularization clinically, and gastric ulcers do not relapse after being healed.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of medicine and preparation method for the treatment of gastric ulcer.
Background technology
Peptic Ulcers or peptic ulcer are a kind of common digestive tract disease, esophagus, stomach or duodenum can be betided, also can betide near stomach-intestinal anastomosis mouth or containing in the Meckel diverticulum of gastric mucosa, because gastric ulcer and duodenal ulcer the most common, therefore general so-called peptic ulcer refers to gastric ulcer and duodenal ulcer.Why it is referred to as peptic ulcer, because previously think that gastric ulcer and duodenal ulcer are because gastric acid and pepsin formed mucosa autodigestion, in fact gastric acid and pepsin are the one of the main reasons of ulcer, also have other reasons to form peptic ulcer.Because the cause of disease of gastric ulcer and duodenal ulcer and clinical symptoms have many similarities, being sometimes difficult to differentiation is gastric ulcer or duodenal ulcer, is therefore often diagnosed as peptic ulcer, or taste-blindness rate.If the clear and definite ulcer of energy is at stomach or duodenum, that just can directly be diagnosed as gastric ulcer or duodenal ulcer.Epigastrium pain is the cardinal symptom of primary disease.Multidigit in epigastrium, after also can appearing at left upper abdomen or breastbone, xiphoid-process.Be often dull pain, dull pain, distending pain, burn sample pain.The pain of gastric ulcer is many to be occurred in 1 hour after the meal, alleviated gradually after 1 ~ 2 hour, until reappear the above-mentioned rhythm and pace of moving things again after the feed of lower meal.Some patients can be asymptomatic, or using complication such as hemorrhage, perforation as onset symptoms.
The development of economic society, the continuous change of living habit, more and more abundanter material base, all makes the rule of life of people that great change occurs.Now is social, gastropathy has become a kind of quotidian disease, problem that a lot of people feels there be nothing large, this idea is grave error in fact, if gastropathy prevention and therapy is not in time the generation that possible cause the every disease of health, so we must treat timely and nurse one's health during gastropathy, the easy complicated by ulcer of chronic gastritis is sick, and ulcer is generally substantially occurring in gastritis.The factors such as the morbidity of gastric ulcer and diet, occupation, smoking, heredity are relevant, and sphincter of pylorus dysfunction or bile reflux etc., be gastric acid secretion can be caused to increase and destroy gastric mucosal barrier, also on the basis that gastritis occurs, ulcer can be formed further.
Current gastric ulcer is main mainly with western medicine, though the state of an illness can control, easily recurrence after treatment, be usually difficult to radical cure, and have certain side effect to human body, cost is higher, and therefore a kind of medicine of being free from side effects and can treating gastric ulcer is badly in need of in country.
Summary of the invention
The invention provides a kind of medicine and preparation method for the treatment of gastric ulcer; Selected by medicine of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of promoting the circulation of QI to relieve pain, tonifying-Yin and nourishing-stomach, benefiting QI and nourishing blood, expelling wind and cold, to treatment gastric ulcer, there is unique curative effect, and it is evident in efficacy, good stability, non-relapse after healing, with low cost, taking convenience, without any side effects, treating both the principal and secondary aspects of a disease, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for gastric ulcer, raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 15 ~ 33 parts of bean curd 14 ~ 32 parts of Radix Et Rhizoma Fagopyri Tatarici 14 ~ 32 parts of Radix Cryptolepis sinensis 13 ~ 31 parts
Fructus Piperis 12 ~ 30 parts of Cortex Clausenae Excavataes 12 ~ 30 parts of Papilio machaon L.s 11 ~ 29 parts of Alpinia japonica (Thunb.) Miq.s 10 ~ 28 parts
Folium Elaeagni delavayi 10 ~ 28 portions of Herba menyanthiss 9 ~ 27 parts of Herba Ardisiae Maculosaes 9 ~ 27 portions of jasmines 7 ~ 25 parts
Dendrobium jenkinsii Wall ex Lindl． 7 ~ 25 portions of Flos Rosae Rugosaes 3 ~ 22 parts of Radix potentillae anserinae 3 ~ 22 parts of Caulis seu radix berberidis virgetoris 2 ~ 20 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 18 ~ 30 parts of bean curd 17 ~ 29 parts of Radix Et Rhizoma Fagopyri Tatarici 17 ~ 29 parts of Radix Cryptolepis sinensis 16 ~ 28 parts
Fructus Piperis 15 ~ 27 parts of Cortex Clausenae Excavataes 15 ~ 27 parts of Papilio machaon L.s 14 ~ 26 parts of Alpinia japonica (Thunb.) Miq.s 13 ~ 25 parts
Folium Elaeagni delavayi 13 ~ 25 portions of Herba menyanthiss 12 ~ 24 parts of Herba Ardisiae Maculosaes 12 ~ 24 portions of jasmines 10 ~ 22 parts
Dendrobium jenkinsii Wall ex Lindl． 10 ~ 22 portions of Flos Rosae Rugosaes 7 ~ 19 parts of Radix potentillae anserinae 7 ~ 19 parts of Caulis seu radix berberidis virgetoris 5 ~ 17 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 21 ~ 27 parts of bean curd 20 ~ 26 parts of Radix Et Rhizoma Fagopyri Tatarici 20 ~ 26 parts of Radix Cryptolepis sinensis 19 ~ 25 parts
Fructus Piperis 18 ~ 24 parts of Cortex Clausenae Excavataes 18 ~ 24 parts of Papilio machaon L.s 17 ~ 23 parts of Alpinia japonica (Thunb.) Miq.s 16 ~ 22 parts
Folium Elaeagni delavayi 16 ~ 22 portions of Herba menyanthiss 15 ~ 21 parts of Herba Ardisiae Maculosaes 15 ~ 21 portions of jasmines 13 ~ 19 parts
Dendrobium jenkinsii Wall ex Lindl． 13 ~ 19 portions of Flos Rosae Rugosaes 10 ~ 16 parts of Radix potentillae anserinae 10 ~ 16 parts of Caulis seu radix berberidis virgetoris 8 ~ 14 parts.
Raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 24 parts of bean curd 23 parts of Radix Et Rhizoma Fagopyri Tatarici 23 parts of Radix Cryptolepis sinensis 22 parts
Fructus Piperis 21 parts of Cortex Clausenae Excavataes 21 parts of Papilio machaon L.s 20 parts of Alpinia japonica (Thunb.) Miq.s 19 parts
Folium Elaeagni delavayi 19 portions of Herba menyanthiss 18 parts of Herba Ardisiae Maculosaes 18 portions of jasmines 16 parts
Dendrobium jenkinsii Wall ex Lindl． 16 portions of Flos Rosae Rugosaes 13 parts of Radix potentillae anserinae 13 parts of Caulis seu radix berberidis virgetoris 11 parts.
Treat a preparation method for the medicine of gastric ulcer, comprise following processing step:
(1) Cacumen et folium sageretiae, Radix Et Rhizoma Fagopyri Tatarici, Herba Ardisiae Maculosae and Flos Rosae Rugosae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(2) bean curd, Cortex Clausenae Excavatae, Papilio machaon L., Alpinia japonica (Thunb.) Miq., Folium Elaeagni delavayi and Radix potentillae anserinae are put into container, carry out pulverization process, grind into powder, 180 object fine powders must be, for subsequent use;
(3) Radix Cryptolepis sinensis, Fructus Piperis, jasmine, Dendrobium jenkinsii Wall ex Lindl． and Caulis seu radix berberidis virgetori are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(4) cleaned by Herba menyanthis, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by after thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine of described treatment gastric ulcer.
The property of medicine of the present invention's Chinese medicine used is as follows:
Cacumen et folium sageretiae: sweet in the mouth, light, property is put down; Return lung, kidney channel.Sending down the abnormal ascending QI, reduces phlegm, expelling wind and removing dampness.Main cough, asthma, stomachache, the arthroncus of knee, edema." register planted by Guangxi medicine " carries: " toxic removing, granulation promoting.Control skin ulcer scabies.”
Bean curd: bitter in the mouth, sweet, property is put down; Return stomach warp.Stomach invigorating disappears band, clearing heat and freeing strangury.Cure mainly regurgitation, dysentery, discharging fresh blood stool, leukorrhagia, stranguria with turbid discharge, itching eruption due to wind-heat in blood." detailed outline is picked up any lost article from the road " carries: " control stranguria with turbid discharge, enrich blood.”
Radix Et Rhizoma Fagopyri Tatarici: sweet in the mouth, property is put down, and mild toxicity, returns spleen, stomach, large intestine channel.Spleen invigorating row is stagnant, regulating QI to relieve pain, removing toxic substances and promoting subsidence of swelling.Cure mainly epigastric distending pain, dyspepsia, dysentery, lumbago and skelalgia, traumatic injury, carbuncle malignant boil, lyssodexis." Inner Mongol Chinese herbal medicine " carries: " removing damp and stopping pain, removing toxic substances and promoting subsidence of swelling, stomach invigorating.Control traumatic injury, lumbago and skelalgia, sore and toxic, dyspepsia.”
Radix Cryptolepis sinensis: sweet in the mouth, light, cool in nature.Slightly poisonous.Heat-clearing and toxic substances removing, eliminating stasis to stop pain, hemostasis.For hemoptysis of pulmonary tuberculosis, lung-heat is spat blood, gastrorrhagia, venom, sore ulcer, scabies, traumatic injury knife injury.
Fructus Piperis: acrid in the mouth, peppery.Warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, expectorant, removing toxic substances.Control cold-phlegm food stagnation, coldness and pain in the epigastrium, regurgitation, vomiting clear water, has loose bowels, cold-dysentery.And separate bromatotoxin." Haiyao Bencao, Oversea Materia Medica " carries: " remove gastric qi cold caused by deficiency, dyspepsia does not disappear, cholera QI rising in reverse order, sudden attack of pain in the chest and abdomen, and cold air upper punch is gentle.”
Cortex Clausenae Excavatae: bitter in the mouth, micro-pungent, warm in nature; Return kidney, lung, urinary bladder channel.Expelling wind and cold, promoting the circulation of QI to relieve pain, dehumidifying detumescence.Cure mainly cold, fever, malaria, stomachache, edema, rheumatic arthritis.Fracture is controlled in external, bruise, eczema." choosing of Yunnan Chinese herbal medicine " carries: " dispelling wind to relieve the exterior syndrome, promoting the circulation of QI to relieve pain, preventing the attack (or recurrence) of malaria, parasite killing.Control sense, influenza, malaria, stomachache.”
Papilio machaon L.: acrid in the mouth, sweet, warm in nature; Return liver, stomach warp.Regulate the flow of vital energy, blood stasis dispelling, pain relieving.Main gastric abscess, hernia is suffered from abdominal pain, and singultus is dysphagic." conventional glossary of Herbs and Drugs among the people " carries: " treat for stomachache.”
Alpinia japonica (Thunb.) Miq.: acrid in the mouth, warm in nature.Dispelling wind and removing obstruction in the collateral, regulating QI to relieve pain.For rheumatic arthritis, traumatic injury, toothache, stomachache." vegetation is side just " carries: " separate large poison, promoting the circulation of blood repercussive, saturating muscles and bones.Dispelling the wind and dampness pathogens numb limbs and tense tendons, decoction; Apoplexy insensitive impediment, decocts soup and washes.”
Folium Elaeagni delavayi: sweet in the mouth, acid, light, property is put down; Return lung, kidney, urinary bladder channel.Diuresis and expelling stone, relieving cough and relieving asthma, promoting the circulation of QI to relieve pain.Cure mainly chronic nephritis, stomachache, chronic bronchitis, bronchial asthma.
Herba menyanthis: sweet in the mouth, micro-hardship, cold in nature; GUIXIN, spleen channel.Clearing away heat and promoting diuresis, stomach invigorating, calms the nerves.For gastritis, dyspepsia, cholecystitis, jaundice, hypertension, cardiopalmus, insomnia." the conventional Chinese herbal medicine handbook in the north " carries: " strengthening the spleen to promote digestion, tranquilizing by nourishing the heart.Control gastritis, stomachache, dyspepsia, palpitation and insomnia, irritability.”
Herba Ardisiae Maculosae: acrid in the mouth, hardship, slightly warm in nature; Return liver, kidney, lung meridian.Promoting blood circulation and stopping pain, clearing throat.Main traumatic injury, fracture, rheumatic arthralgia, diphtheria, laryngopharynx swelling and pain, gastric ulcer.
Jasmine: acrid in the mouth, sweet, property is put down; GUIXIN, liver, spleen, lung, kidney, the Five Classics.Energy removing dampness for regulating stomach, resolving depression of regulating the flow of vital energy.Cure mainly taste turbid damp not change, eat gastral cavity less vexed, diarrhoea or dysentery stomachache.Modern medicine study confirms, jasmine has the effect of liver heat removing and eyesight improving, makes people's life lengthening, physical and mental health.
Dendrobium jenkinsii Wall ex Lindl．: sweet in the mouth, light, cool in nature; Attach to the lung and stomach meridians.Nourishing the lung to arrest cough, tonifying-Yin and nourishing-stomach.Cure mainly cough due to lung-heat, pulmonary tuberculosis, asthma, dysentery, stomatitis, stomachache, infant malnutrition.
Flos Rosae Rugosae: sweet in the mouth, micro-hardship, warm in nature; Return liver, spleen channel.To regulate the flow of vital energy resolving depression, regulating menstruation by adjusting the flow of blood.Chest and diaphragm caused by main depression of liver-QI is full vexed, and gastral cavity side of body distending pain, breast is done swollen, menoxenia, and dysentery is had loose bowels, leukorrhagia, traumatic injury carbuncle." book on Chinese herbal medicine is new again " carries: " the strongly fragrant gas of soothing liver-QI gallbladder, spleen invigorating pathogenic fire reducing.Control cold type of pain in abdomen, gastral cavilty is long-pending cold, and holding concurrently can removing blood stasis.”
Radix potentillae anserinae: sweet in the mouth, property is put down; Return spleen, stomach warp.Fill blood, strengthening the spleen and stomach, promoting the production of body fluid to quench thirst, dampness removing.For anemia after being ill, malnutrition, insufficiency of the spleen diarrhoea, rheumatic arthralgia." Chinese herbal medicine is commonly used in Tibet " carries: " vigorate qi and replenish the blood, controls insufficiency of the spleen diarrhoea, after being ill anemia, malnutrition for invigorating spleen and reinforcing stomach, promoting the production of body fluid to quench thirst.”
Caulis seu radix berberidis virgetori: bitter in the mouth, cold in nature; Return liver, stomach, large intestine channel.Heat-clearing and toxic substances removing.Treating the liver is scorching, cholecystitis, enteritis, bacillary dysentery, pharyngolaryngitis, conjunctivitis, urethritis, sore swollen toxin." Guangxi Chinese herbal medicine " carries: " heat-clearing and toxic substances removing.Control bacillary dysentery, gastroenteritis, pharyngolaryngitis, stomatitis, urethritis, acute conjunctivitis, skin infection festers.Prevention epidemic encephalitis.”
The present invention compared with prior art, has following beneficial effect:
Selected by medicine of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of promoting the circulation of QI to relieve pain, tonifying-Yin and nourishing-stomach, benefiting QI and nourishing blood, expelling wind and cold, to treatment gastric ulcer, there is unique curative effect, and it is evident in efficacy, good stability, non-relapse after healing, with low cost, taking convenience, without any side effects, treating both the principal and secondary aspects of a disease, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of effective ingredient of the present invention and weight are:
Cacumen et folium sageretiae 30g bean curd 29g Radix Et Rhizoma Fagopyri Tatarici 29g Radix Cryptolepis sinensis 28g
Fructus Piperis 27g Cortex Clausenae Excavatae 27g Papilio machaon L. 26g Alpinia japonica (Thunb.) Miq. 25g
Folium Elaeagni delavayi 25g Herba menyanthis 24g Herba Ardisiae Maculosae 24g jasmine 22g
Dendrobium jenkinsii Wall ex Lindl． 22g Flos Rosae Rugosae 19g Radix potentillae anserinae 19g Caulis seu radix berberidis virgetori 17g.
Treat a preparation method for the medicine of gastric ulcer, comprise following processing step:
(1) Cacumen et folium sageretiae, Radix Et Rhizoma Fagopyri Tatarici, Herba Ardisiae Maculosae and Flos Rosae Rugosae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(2) bean curd, Cortex Clausenae Excavatae, Papilio machaon L., Alpinia japonica (Thunb.) Miq., Folium Elaeagni delavayi and Radix potentillae anserinae are put into container, carry out pulverization process, grind into powder, 180 object fine powders must be, for subsequent use;
(3) Radix Cryptolepis sinensis, Fructus Piperis, jasmine, Dendrobium jenkinsii Wall ex Lindl． and Caulis seu radix berberidis virgetori are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(4) cleaned by Herba menyanthis, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by after thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine of described treatment gastric ulcer.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 3 (every sheet 0.3g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.Embodiment 2
The raw material composition of effective ingredient of the present invention and weight are:
Cacumen et folium sageretiae 27g bean curd 26g Radix Et Rhizoma Fagopyri Tatarici 26g Radix Cryptolepis sinensis 25g
Fructus Piperis 24g Cortex Clausenae Excavatae 24g Papilio machaon L. 23g Alpinia japonica (Thunb.) Miq. 22g
Folium Elaeagni delavayi 22g Herba menyanthis 21g Herba Ardisiae Maculosae 21g jasmine 19g
Dendrobium jenkinsii Wall ex Lindl． 19g Flos Rosae Rugosae 16g Radix potentillae anserinae 16g Caulis seu radix berberidis virgetori 14g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of effective ingredient of the present invention and weight are:
Cacumen et folium sageretiae 24g bean curd 23g Radix Et Rhizoma Fagopyri Tatarici 23g Radix Cryptolepis sinensis 22g
Fructus Piperis 21g Cortex Clausenae Excavatae 21g Papilio machaon L. 20g Alpinia japonica (Thunb.) Miq. 19g
Folium Elaeagni delavayi 19g Herba menyanthis 18g Herba Ardisiae Maculosae 18g jasmine 16g
Dendrobium jenkinsii Wall ex Lindl． 16g Flos Rosae Rugosae 13g Radix potentillae anserinae 13g Caulis seu radix berberidis virgetori 11g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of effective ingredient of the present invention and weight are:
Cacumen et folium sageretiae 21g bean curd 20g Radix Et Rhizoma Fagopyri Tatarici 20g Radix Cryptolepis sinensis 19g
Fructus Piperis 18g Cortex Clausenae Excavatae 18g Papilio machaon L. 17g Alpinia japonica (Thunb.) Miq. 16g
Folium Elaeagni delavayi 16g Herba menyanthis 15g Herba Ardisiae Maculosae 15g jasmine 13g
Dendrobium jenkinsii Wall ex Lindl． 13g Flos Rosae Rugosae 10g Radix potentillae anserinae 10g Caulis seu radix berberidis virgetori 8g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of effective ingredient of the present invention and weight are:
Cacumen et folium sageretiae 18g bean curd 17g Radix Et Rhizoma Fagopyri Tatarici 17g Radix Cryptolepis sinensis 16g
Fructus Piperis 15g Cortex Clausenae Excavatae 15g Papilio machaon L. 14g Alpinia japonica (Thunb.) Miq. 13g
Folium Elaeagni delavayi 13g Herba menyanthis 12g Herba Ardisiae Maculosae 12g jasmine 10g
Dendrobium jenkinsii Wall ex Lindl． 10g Flos Rosae Rugosae 7g Radix potentillae anserinae 7g Caulis seu radix berberidis virgetori 5g.
The process for preparing medicine processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the medicine for the treatment of gastric ulcer, select the routine clinical observation of patients w ith peptic ulcer disease 190 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 95 example, wherein male 47 example, women 48 example, 20 ~ 65 years old age, 42.5 years old mean age, average course of disease 4 years; Matched group 95 example, wherein male 48 example, women 47 example, 21 ~ 64 years old age, 42.5 years old mean age, average course of disease 4 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes medicine of the present invention, oral, every day 2 times, each 1 time sooner or later, each 3 (every sheet 0.3g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes acetylspiramycin tablet, oral, adult human dose, a 0.2 ~ 0.3g, 4 times on the one, doubles first.
3, efficacy determination:
(1) cure: sings and symptoms all disappears, and stomach functional rehabilitation is normal.
(2) effective: sings and symptoms obviously alleviates, stomach function takes a turn for the better to some extent.
(3) effective: sings and symptoms alleviates to some extent, and stomach function is clearly better.
(4) invalid: by treating rear sings and symptoms without alleviating or increasing the weight of.
4, result:
Select in the treatment group of medicine of the present invention, cure 58 examples, effective 24 examples, effective 10 examples, invalid 3 examples, cure rate 61.1%, total effective rate 96.8%.
56 examples are cured, effective 20 examples, effective 8 examples, invalid 11 examples, cure rate 58.9%, total effective rate 88.4% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Yuan, man, 22 years old, Baiyin people.Patient suffers from gastric ulcer half a year, can not eat the irritant thing of stomach, usually often occur stomachache, acid regurgitation, vomiting phenomenon, through taking Drug therapy of the present invention, after taking 1 course for the treatment of, stomachache alleviates, and number of times reduces, after taking 2 courses for the treatment of, stomachache transference cure, recovery from illness, follows up a case by regular visits to and does not recur so far.
2, Lu, female, 25 years old, people from Handan, Hebei.Patient suffers from gastric ulcer 3 years, dining started to occur that rhythmicity is had a stomachache after half an hour, and used multiple Drug therapy, therapeutic effect is not good, to our hospital upon somebody's introduction, take Drug therapy of the present invention, after taking 1 course for the treatment of, symptom obviously alleviates, after taking 3 courses for the treatment of, symptom all disappears, recovery from illness, follows up a case by regular visits to without recurrence after 1 year.
3, Song, female, 30 years old, people from Changzhi, Shanxi.Patient's distending pain under xiphoid-process before 1 year, has feeling of repletion after meal, occasionally has heating installation, returns acid, dull pain under xiphoid-process, in paroxysmal, is admitted to hospital and does gastroscopy, be diagnosed as gastric ulcer, doctor recommends to take Drug therapy of the present invention, and take 1 course for the treatment of, symptom takes a turn for the better to some extent, after continuing to take 2 courses for the treatment of, gastroscopy transference cure, recovery from illness, recurrence of following up a case by regular visits to that so far there are no.
4, leaf, man, 33 years old, people from Shiyan, Hubei.Patient's appetite is poor, and without becoming thin, xiphoid-process presses down pain, and by treating gastritis half a year, symptom is without alleviation, also without obviously worsening, being admitted to hospital and doing gastroscopy, being diagnosed as gastric ulcer, giving Drug therapy of the present invention, after taking 2 courses for the treatment of, again check, display recovery from illness, follows up a case by regular visits to after half a year and has no recurrence.
5, desolate certain, man, 48 years old, people from Xinyu, Jiangxi.Patient suffers from gastric ulcer 2 years, often sensation hungry uncomfortable, pantothenic acid, after the meal Upper abdominal pain, took multiple Drug therapy, therapeutic effect is not good, normal recurrent exerbation, to our hospital afterwards, take Drug therapy of the present invention, after taking 1 course for the treatment of, stomachache is not reaccessed, abdominal distention, belch, nausea alleviate, and after continuing to take 2 courses for the treatment of, all diseases disappear, body weight increases than before, through gastroscopy gastric ulcer healing.
6, Cai, female, 51 years old, Law Firm Suzhou Jiangsu people.Patient because of the fatigue that works, pressure comparatively large, and vinegar-pepper raw food liked by diet, causes suffering from gastric ulcer more than 1 year, the twinge of frequent sensation gastral cavilty, abdominal distention, belch, feel sick, and health is comparatively become thin, and takes Drug therapy of the present invention, after taking 1 course for the treatment of, pantothenic acid and after the meal Upper abdominal pain greatly alleviate, and after taking 2 courses for the treatment of, check gastric ulcer disappears, recovery from illness, follows up a case by regular visits to and does not recur so far.
Claims (5)
1. treat a medicine for gastric ulcer, it is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 15 ~ 33 parts of bean curd 14 ~ 32 parts of Radix Et Rhizoma Fagopyri Tatarici 14 ~ 32 parts of Radix Cryptolepis sinensis 13 ~ 31 parts
Fructus Piperis 12 ~ 30 parts of Cortex Clausenae Excavataes 12 ~ 30 parts of Papilio machaon L.s 11 ~ 29 parts of Alpinia japonica (Thunb.) Miq.s 10 ~ 28 parts
Folium Elaeagni delavayi 10 ~ 28 portions of Herba menyanthiss 9 ~ 27 parts of Herba Ardisiae Maculosaes 9 ~ 27 portions of jasmines 7 ~ 25 parts
Dendrobium jenkinsii Wall ex Lindl． 7 ~ 25 portions of Flos Rosae Rugosaes 3 ~ 22 parts of Radix potentillae anserinae 3 ~ 22 parts of Caulis seu radix berberidis virgetoris 2 ~ 20 parts.
2. a kind of medicine for the treatment of gastric ulcer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 18 ~ 30 parts of bean curd 17 ~ 29 parts of Radix Et Rhizoma Fagopyri Tatarici 17 ~ 29 parts of Radix Cryptolepis sinensis 16 ~ 28 parts
Fructus Piperis 15 ~ 27 parts of Cortex Clausenae Excavataes 15 ~ 27 parts of Papilio machaon L.s 14 ~ 26 parts of Alpinia japonica (Thunb.) Miq.s 13 ~ 25 parts
Folium Elaeagni delavayi 13 ~ 25 portions of Herba menyanthiss 12 ~ 24 parts of Herba Ardisiae Maculosaes 12 ~ 24 portions of jasmines 10 ~ 22 parts
Dendrobium jenkinsii Wall ex Lindl． 10 ~ 22 portions of Flos Rosae Rugosaes 7 ~ 19 parts of Radix potentillae anserinae 7 ~ 19 parts of Caulis seu radix berberidis virgetoris 5 ~ 17 parts.
3. a kind of medicine for the treatment of gastric ulcer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 21 ~ 27 parts of bean curd 20 ~ 26 parts of Radix Et Rhizoma Fagopyri Tatarici 20 ~ 26 parts of Radix Cryptolepis sinensis 19 ~ 25 parts
Fructus Piperis 18 ~ 24 parts of Cortex Clausenae Excavataes 18 ~ 24 parts of Papilio machaon L.s 17 ~ 23 parts of Alpinia japonica (Thunb.) Miq.s 16 ~ 22 parts
Folium Elaeagni delavayi 16 ~ 22 portions of Herba menyanthiss 15 ~ 21 parts of Herba Ardisiae Maculosaes 15 ~ 21 portions of jasmines 13 ~ 19 parts
Dendrobium jenkinsii Wall ex Lindl． 13 ~ 19 portions of Flos Rosae Rugosaes 10 ~ 16 parts of Radix potentillae anserinae 10 ~ 16 parts of Caulis seu radix berberidis virgetoris 8 ~ 14 parts.
4. a kind of medicine for the treatment of gastric ulcer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
Cacumen et folium sageretiae 24 parts of bean curd 23 parts of Radix Et Rhizoma Fagopyri Tatarici 23 parts of Radix Cryptolepis sinensis 22 parts
Fructus Piperis 21 parts of Cortex Clausenae Excavataes 21 parts of Papilio machaon L.s 20 parts of Alpinia japonica (Thunb.) Miq.s 19 parts
Folium Elaeagni delavayi 19 portions of Herba menyanthiss 18 parts of Herba Ardisiae Maculosaes 18 portions of jasmines 16 parts
Dendrobium jenkinsii Wall ex Lindl． 16 portions of Flos Rosae Rugosaes 13 parts of Radix potentillae anserinae 13 parts of Caulis seu radix berberidis virgetoris 11 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the medicine of gastric ulcer, it is characterized in that: comprise following processing step:
(1) Cacumen et folium sageretiae, Radix Et Rhizoma Fagopyri Tatarici, Herba Ardisiae Maculosae and Flos Rosae Rugosae are cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(2) bean curd, Cortex Clausenae Excavatae, Papilio machaon L., Alpinia japonica (Thunb.) Miq., Folium Elaeagni delavayi and Radix potentillae anserinae are put into container, carry out pulverization process, grind into powder, 180 object fine powders must be, for subsequent use;
(3) Radix Cryptolepis sinensis, Fructus Piperis, jasmine, Dendrobium jenkinsii Wall ex Lindl． and Caulis seu radix berberidis virgetori are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(4) cleaned by Herba menyanthis, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(5) by after thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the medicine of described treatment gastric ulcer.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102309696A (en) * | 2011-09-22 | 2012-01-11 | 黄雨昕 | Traditional Chinese medicine for treating gastric ulcer |
| CN103417894A (en) * | 2013-09-05 | 2013-12-04 | 单光珍 | Traditional Chinese medicine preparation for treating gastric ulcer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102309696A (en) * | 2011-09-22 | 2012-01-11 | 黄雨昕 | Traditional Chinese medicine for treating gastric ulcer |
| CN103417894A (en) * | 2013-09-05 | 2013-12-04 | 单光珍 | Traditional Chinese medicine preparation for treating gastric ulcer |
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Application publication date: 20160113 |