CN103550746A - Traditional Chinese medicine preparation for treating vascular disease - Google Patents
Traditional Chinese medicine preparation for treating vascular disease Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating vascular disease, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation comprises active ingredients prepared from the following raw materials of oenothera biennis, hawthorn, kelp, eggplant, radix puerariae, tomato, agilawood, red jujube, ligusticum wallichii, pawpaw, nacre mother of pearl, banana, celery, polygonum multiflorum, fresh ginger and mung bean. The traditional Chinese medicine preparation has the effects of relaxing blood vessels, easing pain and diminishing inflammation, lowering blood lipid and protecting myocardium, shows an obvious effects on treating coronary heart disease, stenocardia, hyperlipidemia, myocardial ischemia, heart irrythmia, cardiac failure and other vascular diseases, is low in cost, fast to act, and free of toxic and side effects, and has the total treatment effective rate up to 97%.
Description
Affiliated technical field
The present invention relates to the field of Chinese medicines, relate in particular to a kind of Chinese medicine preparation of Cardiovarscular.
Background technology
Cardiovascular disease, be called again blood circulation diseases, a series of diseases that relate to blood circulation, blood circulation refers to hemophoric Organ and tissue in human body, cardiovascular disease comprises coronary heart diseases and angina pectoris etc., coronary heart diseases and angina pectoris is due to coronary insufficiency, and cardiac muscle ischemia sharply, temporary transient, anoxia is caused, belongs to the traditional Chinese medical science " thoracic obstruction " category.Since last century the fifties, the cardiovascular disease such as coronary heart diseases and angina pectoris have become the third-largest death factors of the mankind except cerebrovascular disease, malignant tumor.
At present, treat the method for coronary heart diseases and angina pectoris with blood vessel dilating, reduction blood glucose viscosity, antiplatelet aggregation, anticoagulations etc. are main, Chinese medicine and Western medicine are all being brought into play effect separately.Traditional Western medicine of application is nitric acid lipid, beta-receptor resistance preparation, calcium antagonist etc., though onset is rapid, all exists larger toxic and side effects, should not take for a long time, and these medicines mostly is symptomatic treatment, in the face of course advancement is without larger effect; Chinese medicine aspect, the effective ingredient onset of conventional tablet and capsule is slow, and bioavailability is lower; Injection is rapid-action, but is not suitable for long-term prescription.
In recent years, the good drop pill of market reaction, as FUFANG DANSHEN DIWAN, SUXIAO JIUXIN WAN etc., obtained certain clinical application effect, but its indication is more single, cannot meet the needs of clinical various cardiovascular disease.Need clinically a kind of deficiency that makes up existing medicine for safe, quick-acting, the reliable medicine of qi stagnation and blood stasis type coronary heart diseases and angina pectoris.
Summary of the invention
The invention provides a kind of Chinese medicine preparation of Cardiovarscular; Chinese medicine preparation of the present invention has the blood vessel of releiving, easing pain and diminishing inflammation, reduction blood fat, protects myocardium effect; the multiple cardiovascular disease such as treatment coronary heart diseases and angina pectoris, hyperlipidemia, myocardial ischemia, arrhythmia, heart failure are had to significant curative effect; and cost is low, instant effect; without any side effects, treatment total effective rate is up to 97%.
For achieving the above object, technical scheme of the present invention is implemented as follows:
A Chinese medicine preparation for Cardiovarscular, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
41～76 parts of 46～76 portions of Fructus Solani melongenaes of 46～81 portions of Thallus Laminariae (Thallus Eckloniae)s of 56～81 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
31～66 parts of 36～66 portions of Fructus Jujubaes of 36～71 portions of Lignum Aquilariae Resinatum of 36～76 parts of Fructus Lycopersici esculenti of Radix Puerariae
21～51 parts, 26～51 portions of Fructus Musaes of 26～56 parts of Concha Margaritiferas of 31～61 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
11～36 parts, 11～41 portions of Semen phaseoli radiatis of 16～41 portions of Rhizoma Zingiberis Recenss of 16～46 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
46～71 parts of 51～71 portions of Fructus Solani melongenaes of 51～76 portions of Thallus Laminariae (Thallus Eckloniae)s of 61～76 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
36～61 parts of 41～61 portions of Fructus Jujubaes of 41～66 portions of Lignum Aquilariae Resinatum of 41～71 parts of Fructus Lycopersici esculenti of Radix Puerariae
26～46 parts, 31～46 portions of Fructus Musaes of 31～51 parts of Concha Margaritiferas of 36～56 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
16～31 parts, 16～36 portions of Semen phaseoli radiatis of 21～36 portions of Rhizoma Zingiberis Recenss of 21～41 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
51～66 parts of 56～66 portions of Fructus Solani melongenaes of 56～71 portions of Thallus Laminariae (Thallus Eckloniae)s of 66～71 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
41～56 parts of 46～56 portions of Fructus Jujubaes of 46～61 portions of Lignum Aquilariae Resinatum of 46～66 parts of Fructus Lycopersici esculenti of Radix Puerariae
31～41 parts, 36～41 portions of Fructus Musaes of 36～46 parts of Concha Margaritiferas of 41～51 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
21～26 parts, 21～31 portions of Semen phaseoli radiatis of 26～31 portions of Rhizoma Zingiberis Recenss of 26～36 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
59 parts of 61 portions of Fructus Solani melongenaes of 63 portions of Thallus Laminariae (Thallus Eckloniae)s of 68 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
48 parts of 51 portions of Fructus Jujubaes of 56 portions of Lignum Aquilariae Resinatum of 56 parts of Fructus Lycopersici esculenti of Radix Puerariae
36 parts, 38 portions of Fructus Musaes of 41 parts of Concha Margaritiferas of 46 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
24 parts, 26 portions of Semen phaseoli radiatis of 28 portions of Rhizoma Zingiberis Recenss of 31 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
The preparation method of Chinese medicine preparation, comprise following processing step:
(1) Radix Oenotherae erythrosepalae, Thallus Laminariae (Thallus Eckloniae), Fructus Jujubae, Fructus Chaenomelis, Concha Margaritifera and Fructus Musae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, filtrate is condensed into the thick paste that at 60 ℃, relative density is 1.10～1.16, standby;
(2) Fructus Crataegi, Fructus Solani melongenae, Fructus Lycopersici esculenti, Herba Apii graveolentis and Rhizoma Zingiberis Recens are cleaned, put into agitator and rub, filter impurity, stays juice standby;
(3) by Radix Puerariae, Lignum Aquilariae Resinatum and Semen phaseoli radiati decontamination, microwave drying after mix homogeneously, carries out pulverization process, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(4) Rhizoma Chuanxiong and Radix Polygoni Multiflori are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filter, and the thick paste that is 1.11～1.18 by relative density at 65 ℃ of filtrate simmer down tos, standby;
(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation of Cardiovarscular of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix Oenotherae erythrosepalae: sweet in the mouth, hardship, warm in nature.Wind-damp dispelling, bone and muscle strengthening.Main anemofrigid-damp arthralgia, soreness of bones and muscles.Modern medicine study confirms, Radix Oenotherae erythrosepalae can be treated various diseases, and can regulate lipid material content in blood, and the diseases such as the coronary artery that hypercholesterolemia, hyperlipidemia are caused infraction, atherosis and cerebral thrombosis have significant curative effect.
Fructus Crataegi: sweet in the mouth, acid, slightly warm in nature.Appetite-stimulating indigestion-relieving, change stagnant removing food stagnancy, promoting blood circulation to remove blood stasis, the circulation of qi promoting of reducing phlegm.For carnivorous stagnant long-pending, lump in the abdomen, abdominal distention feeling of fullness, stasis blocking stomachache, phlegm retention, have loose bowels, discharging fresh blood stool etc.< < herbal classic > > carries: " sour in the mouth, air cooling, so see its can help digestion long-pending, clots absorbing blood, gas is non-cold.Having stagnates becomes dysentery, prolonged lochia, and holding in lunar part is after-pains.It is stagnant that Fructus Crataegi can enter taste removing food stagnancy, and loose stagnated blood, therefore in harness the river dysentery and puerpera's abdomen piece pain is also.On the whole its merit is longer than dissipating fluid-retention food, strengthening the spleen and stomach, row stagnation of QI, repercussive blood, therefore children's puerpera should polyphagia it." clinic study confirmation, Fructus Crataegi can significantly reduce serum cholesterol and triglyceride, effectively prevents and treats atherosclerosis; Fructus Crataegi can also play heart tonifying and prevent anginal effect by strengthening myocardial contraction, increase cardiac output, coronary artery dilator blood vessel, increase coronary flow, reduction myocardial oxygen consumption etc.
Thallus Laminariae (Thallus Eckloniae): salty in the mouth, cold in nature; Enter stomach warp.Eliminating phlegm and softening indurated mass, the diuretic that expels the heat-evil, relieving cough and asthma, the lipoid and reducing blood pressure of dispelling, eliminating stagnation are anticancer.For under goiter, scrofula, hernia, fall, cough with asthma, edema, hypertension, coronary heart disease, obesity.The beautiful Chinese catalpa medicine of < < solution > > carries: " sluicing is dried, removing mass softening the hard mass.Clearing away heat and promoting diuresis, controls flatulence watery distension, scrofula goiter, and TUI hernia malignant boil, with Sargassum, the same merit of Thallus Laminariae (Thallus Eckloniae).”
Fructus Solani melongenae: sweet in the mouth, cold in nature, nontoxic; Enter spleen, stomach, large intestine channel.Clearing away heat and cooling blood, dissipating blood stasis for subsidence of swelling.< < occupies diet spectrum > > with breath and carries: " invigorate blood circulation, pain relieving, eliminating carbuncle, parasite killing, malaria, all diseases of abdominal mass hernia." modern medicine study confirmation, Fructus Solani melongenae has good blood fat reducing, blood pressure effect.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Induce sweat and bring down a fever, promote the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, hypertension neck pain, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, have loose bowels.< < Compendium of Materia Medica > > carries: " Radix Puerariae, cool in nature, gas is put down, sweet in the mouth, tool heat clearing away, pathogenic fire reducing, all effects of toxin expelling." modern medicine study shows: the isoflavonoid puerarin in Radix Puerariae has certain curative effect to hypertension, hyperlipidemia, hyperglycemia and cardiovascular and cerebrovascular disease.
Fructus Lycopersici esculenti: sweet in the mouth, acid, cool in nature, be slightly cold; Return liver, stomach, lung meridian.Can relieve heat and thirst, yin nourishing, removing heat from blood, has promoting the production of body fluid to quench thirst, invigorating the stomach and promoting digestion, heat-clearing and toxic substances removing, removing heat from blood suppressing the hyperactive liver, blood-supplementing blood-nourishing and orectic effect.Can control the various diseases such as thirsty, inappetence, habitual gingival hemorrhage, anemia, dizziness, cardiopalmus, hypertension, acute, chronic hepatitis, acute and chronic nephritis, nyctalopia and myopia.
Lignum Aquilariae Resinatum: acrid in the mouth, hardship, warm in nature; Return spleen, stomach, kidney, lung meridian.Sending down the abnormal ascending QI warming middle-JIAO, warming the kidney is supporing yang.Cure mainly QI rising in reverse order and pant, vomiting singultus, abdominal distention, waist knee joint cold caused by deficiency, large intestine constipation due to insufficiency, urine qi stranguria, man's cold sperm.< < Japan hanako materia medica > > carries: " in tune, tonifying five ZANG-organs, nourishing essence and tonifying YANG, warm waist knee joint, gas uncharms.Ending tendon transfer, vomiting and diarrhoea, cold air, broken disease addiction, controls cold wind paralysis, and joint is not appointed, and wet wind skin is itched, cardiac and abdominal pain, diarrhea due to disorder of qi.”
Fructus Jujubae: sweet in the mouth, warm in nature; Return spleen, stomach warp.Invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind, the mitigation property of medicine.Treating acute and chronic hepatitis, liver cirrhosis, anemia, anaphylactoid purpura.< < Compendium of Materia Medica > > carries: " Fructus Jujubae sweet in the mouth, warm in nature, can invigorating the spleen and replenishing QI, nourishing blood to promote the production of body fluid, is used for the treatment of diseases such as ' insufficiency of the spleen weak, anorexia and loose stool, deficiency of qi and blood '.Normal food Fructus Jujubae can be treated physical weakness, neurasthenia, incoordination between the spleen and stomach, dyspepsia, epersalgia cough, anemia and be become thin, and nourishing the liver preventing cancer function is particularly outstanding, has saying of ' three Fructus Jujubaes of solar eclipse, at the age of one hundred years old bearing one's age well '." pharmacological research discovery, Fructus Jujubae can promote leukocytic generation, reduces serum cholesterol, improves serum albumin, the liver protecting, also contains anticancer in Fructus Jujubae, the material that even can make cancerous cell transform to normal cell.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature; Return liver, gallbladder, heart channel.Blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.Treatment headache, menoxenia, amenorrhea dysmenorrhea, the stagnant raw meat pain of the stasis of blood in puerperal, lump in the abdomen lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia, traumatic injury, ulcer sores.< < medicine origin > > carries: " enrich blood, control headache due to deficiency of blood.”
Fructus Chaenomelis: sweet in the mouth, property is put down, is slightly cold; Return liver, spleen channel.After aid digestion, can also relieve summer heat quench one's thirst, nourishing the lung to arrest cough, suppressing the hyperactive liver, relaxing muscles and tendons, and spleen, removing dampness.Control arthralgia chiefly caused by damp pathogen, beriberi, cholera, vomiting and diarrhoea, stomachache, convulsion.< < Haiyao Bencao, Oversea Materia Medica > > carries: " relieving dyspepsia is quenched the thirst for the stomach function regulating of astringing the lung, reason spleen checking hyperfunction of the liver.”
Concha Margaritifera: salty, cold; Return liver, heart channel.Suppressing the hyperactive liver and subsiding YANG, calm the nerves, calm the frightened improving eyesight, hemostasis.Control dizziness, tinnitus, cardiopalmus, insomnia, demented, infantile convulsion, spits blood, epistaxis, metrorrhagia.< < Chinese medicine voluminous dictionary > > carries: " liver nourishing is cloudy, clearing away liver-fire.Control demented frightened Concha Margaritifera epilepsy, dizziness, tinnitus, heart beating, pleuroperitoneum is swollen, women's heat in blood, metrorrhagia, frightened the jerking of children's sent out convulsion.”
Fructus Musae: sweet in the mouth, cool in nature.Nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst.Energy blood vessel dilating, prevents apoplexy and angina pectoris.< < book on Chinese herbal medicine asks former > > to carry: " lung moistening of quenching the thirst is relieved the effect of alcohol, clear spleen laxation; Spleen-fire Sheng person eats it, instead can antidiarrheal dysentery relieving.”
Herba Apii graveolentis: cool in nature, sweet in the mouth is pungent, nontoxic; Enter liver, gallbladder, heart channel.Clearing heat and relieving fidgetness, cures mainly hypertension, headache, and dizziness, sudden high fever excessive thirst, jaundice, edema, urine heat is puckery unfavorable, menoxenia, leucorrhea with red and white discharge, scrofula, the diseases such as mumps.< < health communication > > carries: " heat is washed in clearing stomach, promoting blood circulation, and tasty and refreshing tooth wets one's whistle, improving eyesight stuffy nose relieving, refreshment stomach invigorating, nourishing the lung to arrest cough.”
Radix Polygoni Multiflori: bitter in the mouth, sweet, puckery, slightly warm in nature; Return liver, kidney channel.Tonic, medicine dispels the wind.Cure mainly blood deficiency anemia, Light-headedness, cardiopalmus, insomnia, the soreness of the waist and knees of the hepatic and renal YIN deficiency, early whitening of beard and hair, tinnitus, seminal emission, dryness of the intestine constipation, chronic malaria body is empty, rubella pruritus, carbuncle sore, scrofula, hemorrhoid.< < the southern regions of the Yunnan Province book on Chinese herbal medicine > > carries: " arresting seminal emission, hard kidney qi are stopped red white turbid urine, and urine reducing, enters blood system, expectorant poison; Control red vitiligo, skin ulcer scabies stubborn dermatitis, skin scabies ancient term for country school, preventing the attack (or recurrence) of malaria, controls intermittent fever due to phlegm.”
Rhizoma Zingiberis Recens: acrid in the mouth, slightly warm in nature; Return lung, spleen, stomach warp.Relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, solving toxin of fish and crab, separates poison of drug.For Deficiency and coldness of spleen and stomach, loss of appetite, nausea and vomiting, or vomiting due to fluid-retention, the vomiting of disorder of stomach-QI; Wind and cold or cold-phlegm cough; Cold, fever with aversion to wind, nasal obstruction headache.< < Mingyi Bielu > > carries: " acrid in the mouth, tepor.Cure mainly cold headache, nasal obstruction, cough with dyspnea, preventing or arresting vomiting is told.”
Semen phaseoli radiati: sweet in the mouth, cold in nature, nontoxic; GUIXIN, stomach warp.Cure mainly long-term dysentery, prolongedly do not heal, summer-heat excessive thirst, cold, fever, cholera is vomited and diarrhoea, and expectorant asthma of heat type is breathed heavily, headache conjunctival congestion, aphtha of the mouth and tongue, edema oliguria, skin infection carbuncle, rubella erysipelas, medicine and alimentary toxicosis.< < Compendium of Materia Medica > > carries: " thick the intestines and stomach, rests the head on, and wind syndrome of head headache is controlled in improving eyesight, contrary except telling, treatment of smallpox poison, sharp swelling.”
The present invention compared with prior art, has following beneficial effect:
Chinese medicine preparation of the present invention has the blood vessel of releiving, easing pain and diminishing inflammation, reduction blood fat, protects myocardium effect; the multiple cardiovascular disease such as treatment coronary heart diseases and angina pectoris, hyperlipidemia, myocardial ischemia, arrhythmia, heart failure are had to significant curative effect; and cost is low, instant effect; without any side effects, treatment total effective rate is up to 97%.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Oenotherae erythrosepalae 76g Fructus Crataegi 76g Thallus Laminariae (Thallus Eckloniae) 71g Fructus Solani melongenae 71g
Radix Puerariae 71g Fructus Lycopersici esculenti 66g Lignum Aquilariae Resinatum 61g Fructus Jujubae 61g
Rhizoma Chuanxiong 56g Fructus Chaenomelis 51g Concha Margaritifera 46g Fructus Musae 46g
Herba Apii graveolentis 41g Radix Polygoni Multiflori 36g Rhizoma Zingiberis Recens 36g Semen phaseoli radiati 31g.
The preparation method of Chinese medicine preparation, comprise following processing step:
(1) Radix Oenotherae erythrosepalae, Thallus Laminariae (Thallus Eckloniae), Fructus Jujubae, Fructus Chaenomelis, Concha Margaritifera and Fructus Musae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, filtrate is condensed into the thick paste that at 60 ℃, relative density is 1.10～1.16, standby;
(2) Fructus Crataegi, Fructus Solani melongenae, Fructus Lycopersici esculenti, Herba Apii graveolentis and Rhizoma Zingiberis Recens are cleaned, put into agitator and rub, filter impurity, stays juice standby;
(3) by Radix Puerariae, Lignum Aquilariae Resinatum and Semen phaseoli radiati decontamination, microwave drying after mix homogeneously, carries out pulverization process, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(4) Rhizoma Chuanxiong and Radix Polygoni Multiflori are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filter, and the thick paste that is 1.11～1.18 by relative density at 65 ℃ of filtrate simmer down tos, standby;
(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation of Cardiovarscular of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 8 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2～3 courses for the treatment of.
Embodiment 2
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Oenotherae erythrosepalae 71g Fructus Crataegi 71g Thallus Laminariae (Thallus Eckloniae) 66g Fructus Solani melongenae 66g
Radix Puerariae 66g Fructus Lycopersici esculenti 61g Lignum Aquilariae Resinatum 56g Fructus Jujubae 56g
Rhizoma Chuanxiong 51g Fructus Chaenomelis 46g Concha Margaritifera 41g Fructus Musae 41g
Herba Apii graveolentis 36g Radix Polygoni Multiflori 31g Rhizoma Zingiberis Recens 31g Semen phaseoli radiati 26g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 3
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Oenotherae erythrosepalae 68g Fructus Crataegi 63g Thallus Laminariae (Thallus Eckloniae) 61g Fructus Solani melongenae 59g
Radix Puerariae 56g Fructus Lycopersici esculenti 56g Lignum Aquilariae Resinatum 51g Fructus Jujubae 48g
Rhizoma Chuanxiong 46g Fructus Chaenomelis 41g Concha Margaritifera 38g Fructus Musae 36g
Herba Apii graveolentis 31g Radix Polygoni Multiflori 28g Rhizoma Zingiberis Recens 26g Semen phaseoli radiati 24g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 4
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Oenotherae erythrosepalae 66g Fructus Crataegi 56g Thallus Laminariae (Thallus Eckloniae) 56g Fructus Solani melongenae 51g
Radix Puerariae 46g Fructus Lycopersici esculenti 46g Lignum Aquilariae Resinatum 46g Fructus Jujubae 41g
Rhizoma Chuanxiong 41g Fructus Chaenomelis 36g Concha Margaritifera 36g Fructus Musae 31g
Herba Apii graveolentis 26g Radix Polygoni Multiflori 26g Rhizoma Zingiberis Recens 21g Semen phaseoli radiati 21g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Embodiment 5
The raw material of Chinese medicine preparation effective ingredient of the present invention forms and weight is:
Radix Oenotherae erythrosepalae 61g Fructus Crataegi 51g Thallus Laminariae (Thallus Eckloniae) 51g Fructus Solani melongenae 46g
Radix Puerariae 41g Fructus Lycopersici esculenti 41g Lignum Aquilariae Resinatum 41g Fructus Jujubae 36g
Rhizoma Chuanxiong 36g Fructus Chaenomelis 31g Concha Margaritifera 31g Fructus Musae 26g
Herba Apii graveolentis 21g Radix Polygoni Multiflori 21g Rhizoma Zingiberis Recens 16g Semen phaseoli radiati 16g.
Chinese medicine preparation preparation method processing step and the usage and dosage of the present embodiment are identical with embodiment 1.
Clinical data:
1, case selection:
Chinese medicine preparation as Cardiovarscular, the routine clinical observation of cardiovascular patient 200 that selection is made a definite diagnosis, patient is divided into two groups for the treatment of group and matched groups, treatment group 100 examples, wherein male's 50 examples at random, women's 50 examples, 40～72 years old age, 55.4 years old mean age, the shortest person of the course of disease 3 months, elder 11 years, average 5.9 years.Matched group 100 examples, male's 51 examples wherein, women's 49 examples, 41～71 years old age, 56.7 years old mean age, the shortest person of the course of disease 4 months, elder 10 years, average 5.3 years.
The course of disease, the degrees of symptoms for the treatment of group and two groups of cases of matched group are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group is taken Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every 0.5g), after meal warm water delivery services; Within 8 days, be 1 course for the treatment of, 1 course for the treatment of of the lighter, severe one can be fully recovered 2～3 courses for the treatment of.
Matched group is taken salt acid amide nitrate, sublingual administration or oral: every day 3 times, each 5～10mk; Within 10 days, be 1 course for the treatment of, 2 courses for the treatment of of the lighter, severe one can be fully recovered 3～5 courses for the treatment of, and the person of being in a bad way is conventionally invalid.
3, efficacy determination:
(1) cure: clinical symptoms sign disappears, and electrocardiogram ischemic glucose recovery is normal, it is normal that cardiovascular function is recovered.
(2) take a turn for the better: clinical symptoms sign disappears substantially, and electrocardiogram ischemic symptom changes to some extent, and cardiovascular function is recovered to some extent.
(3) invalid: clinical symptoms sign does not disappear, and electrocardiogram ischemic symptom is without obvious change.
4, result:
Treatment group and matched group curative effect relatively see the following form.
Above result demonstration, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
5, model case is for example:
(1) Song, man, 43 years old, lawyer, people from Weifang, Shandong.Nervous, cardiopalmus that patient occurred before half a year, the symptoms such as arrhythmia, and with heart strand pain, breathe hard, unable, have a strong impact on work.Through taking Chinese medicine preparation of the present invention after 1 course for the treatment of, nervous, cardiopalmus, arrhythmia transference cure, take 2 courses for the treatment of after heart strand pain disappear, physical recovery is normal on inspection, the state of an illness does not recur so far.
(2) Wang, female, 55 years old, teacher, people from Shenyang, Liaoning.Patient suffers from coronary heart diseases and angina pectoris, cardiac blood supply deficiency disease for many years, though through multi-treatment, poor effect.To our hospital afterwards, take Chinese medicine preparation of the present invention after 1 course for the treatment of, on inspection, the related index such as whole blood viscosity, plasma viscosity and angina pectoris attacks number of times have remarkable improvement, take again Chinese medicine preparation of the present invention after 1 course for the treatment of, clinical symptoms disappears substantially on inspection, and indices reaches normal range substantially, follows up a case by regular visits to without recurrence after 1 year.
(3) Lee, man, 67 years old, retired worker, people from Changchun, Jilin.Patient suffers from hypertension, hyperlipidemia is had a surplus for 5 years, tired rear nervous, dyspnea.Be admitted to hospital and show myocardial ischemia through Electrocardioscopy, coronarography shows sclerosis.Take Chinese medicine preparation of the present invention after 1 course for the treatment of, blood pressure, blood fat are steady, and nervous, dyspnea symptom is eliminated, take Chinese medicine preparation of the present invention after 1 course for the treatment of, Electrocardioscopy shows no longer ischemia of cardiac muscle again, and coronarography shows sclerosis elimination, pay a return visit, the state of an illness does not recur so far.
(4) Guo, female, 70 years old, peasant, Taiyuan, Shanxi people.Patient fell ill before half a year and moves in certain city Yi Jia hospital, through nuclear magnetic resonance check, show that heart coronary artery is atherosis, two lower limb atherosclerosis, underwent coronary contrast examination demonstration, heart anterior descending branch infraction, though carry out operative treatment, but occur unstable angina pectoris, blood pressure is high always.To our hospital afterwards, through doctor, recommend to take Chinese medicine preparation of the present invention, take after 1 course for the treatment of, back cardiac reflex district's pain and symptoms of asthma disappear, and take after 2 courses for the treatment of, have rosy cheeks, repeatedly check that blood pressure, pulse are all normal, mental attitude is good, takes 3 courses for the treatment of by nuclear magnetic resonance check, shows that heart is preced with structure, function is all normal, two lower limb atherosclerosis are also restored, coronarography inspection shows that heart anterior descending branch infraction obviously alleviates, rear return visit, not recurrence in 1 year so far.
Claims (5)
1. a Chinese medicine preparation for Cardiovarscular, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
41～76 parts of 46～76 portions of Fructus Solani melongenaes of 46～81 portions of Thallus Laminariae (Thallus Eckloniae)s of 56～81 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
31～66 parts of 36～66 portions of Fructus Jujubaes of 36～71 portions of Lignum Aquilariae Resinatum of 36～76 parts of Fructus Lycopersici esculenti of Radix Puerariae
21～51 parts, 26～51 portions of Fructus Musaes of 26～56 parts of Concha Margaritiferas of 31～61 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
11～36 parts, 11～41 portions of Semen phaseoli radiatis of 16～41 portions of Rhizoma Zingiberis Recenss of 16～46 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
2. the Chinese medicine preparation of a kind of Cardiovarscular according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
46～71 parts of 51～71 portions of Fructus Solani melongenaes of 51～76 portions of Thallus Laminariae (Thallus Eckloniae)s of 61～76 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
36～61 parts of 41～61 portions of Fructus Jujubaes of 41～66 portions of Lignum Aquilariae Resinatum of 41～71 parts of Fructus Lycopersici esculenti of Radix Puerariae
26～46 parts, 31～46 portions of Fructus Musaes of 31～51 parts of Concha Margaritiferas of 36～56 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
16～31 parts, 16～36 portions of Semen phaseoli radiatis of 21～36 portions of Rhizoma Zingiberis Recenss of 21～41 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
3. the Chinese medicine preparation of a kind of Cardiovarscular according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
51～66 parts of 56～66 portions of Fructus Solani melongenaes of 56～71 portions of Thallus Laminariae (Thallus Eckloniae)s of 66～71 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
41～56 parts of 46～56 portions of Fructus Jujubaes of 46～61 portions of Lignum Aquilariae Resinatum of 46～66 parts of Fructus Lycopersici esculenti of Radix Puerariae
31～41 parts, 36～41 portions of Fructus Musaes of 36～46 parts of Concha Margaritiferas of 41～51 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
21～26 parts, 21～31 portions of Semen phaseoli radiatis of 26～31 portions of Rhizoma Zingiberis Recenss of 26～36 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
4. the Chinese medicine preparation of a kind of Cardiovarscular according to claim 1, is characterized in that: the raw material of making described Chinese medicine preparation effective ingredient forms and parts by weight are:
59 parts of 61 portions of Fructus Solani melongenaes of 63 portions of Thallus Laminariae (Thallus Eckloniae)s of 68 portions of Fructus Crataegis of Radix Oenotherae erythrosepalae
48 parts of 51 portions of Fructus Jujubaes of 56 portions of Lignum Aquilariae Resinatum of 56 parts of Fructus Lycopersici esculenti of Radix Puerariae
36 parts, 38 portions of Fructus Musaes of 41 parts of Concha Margaritiferas of 46 portions of Fructus Chaenomeliss of Rhizoma Chuanxiong
24 parts, 26 portions of Semen phaseoli radiatis of 28 portions of Rhizoma Zingiberis Recenss of 31 parts of Radix Polygoni Multiflori of Herba Apii graveolentis.
5. a preparation method for the Chinese medicine preparation of Cardiovarscular as described in claim 1～4 any one, is characterized in that: comprise following processing step:
(1) Radix Oenotherae erythrosepalae, Thallus Laminariae (Thallus Eckloniae), Fructus Jujubae, Fructus Chaenomelis, Concha Margaritifera and Fructus Musae are cleaned, put into container, add the distilled water of 8～10 times of amounts, soak after 5～6 hours, boil 3～4 hours, extract; Again add 6～8 times of amount distilled water, boil 2～3 hours, extract; Finally, add 4～6 times of amount distilled water, heated and boiled 1～2 hour, extracts; Merge three times extracting solution, filter, obtain filtrate, filtrate is condensed into the thick paste that at 60 ℃, relative density is 1.10～1.16, standby;
(2) Fructus Crataegi, Fructus Solani melongenae, Fructus Lycopersici esculenti, Herba Apii graveolentis and Rhizoma Zingiberis Recens are cleaned, put into agitator and rub, filter impurity, stays juice standby;
(3) by Radix Puerariae, Lignum Aquilariae Resinatum and Semen phaseoli radiati decontamination, microwave drying after mix homogeneously, carries out pulverization process, is placed in mortar and grinds into powder, crosses 160 order fine powders, standby;
(4) Rhizoma Chuanxiong and Radix Polygoni Multiflori are cleaned, immersed 80% the alcohol solution dipping 1～2 hour of 4 times of amounts, heating extraction 3 hours, reclaims ethanol, filter, and the thick paste that is 1.11～1.18 by relative density at 65 ℃ of filtrate simmer down tos, standby;
(5) above-mentioned steps (1)～(4) prepared thick paste, juice and fine powder are mixed, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation of Cardiovarscular of the present invention.
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| CN106039279A (en) * | 2016-08-18 | 2016-10-26 | 赵志坚 | Traditional Chinese medicine for treating stroke sequela and preparation method thereof |
| CN107412508A (en) * | 2017-04-13 | 2017-12-01 | 肖志远 | A kind of Chinese medicine composition of dredging vascellum |
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Application publication date: 20140205 |