CN105232872A - Traditional Chinese medicinal composition for treating chronic dacryocystitis - Google Patents
Traditional Chinese medicinal composition for treating chronic dacryocystitis Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating chronic dacryocystitis. The traditional Chinese medicinal composition is composed an oral administration medicine and an external use medicine. Main effective components of the composition comprise lotus plumule, Lithospermum erythrorhizon, Epigeal Srephaia Root, Hawksbill Turtle, Dioscorea tokoro Makino, Radix Stephaniae Tetrandrae, Faeces Vespertilionum, Climbing Groundsel Herb, Gambir Plant, Glycine max (L.) Merr., Herba Moslae, scorpion, Chinese starjasmine stem, Rhizoma Polygoni Cuspidati, Leaf of Manchurian Catalpa and silkworm excrement. The traditional Chinese medicinal composition is used in an oral administration and external use cooperation manner, has the characteristics of simple preparation, high cure rate, no toxic or side effect, difficult recurrence and low cost, and is worth to be clinically popularized.
Description
Technical field
The invention belongs to the field of Chinese medicines, be specifically related to a kind of Chinese medicine composition for the treatment of chronic dacryocystitis.
Background technology
Dacryocystisis is common ocular disease, and the main subjective symptoms of patient is epiphora, sometimes with the chronic conjunctivitis of this side.Dacryocystisis generally shows as chronic and acute two kinds, and with chronic the most common, acute dacryocystitis is often the acute attack of chronic dacryocystitis.Dacryocystisis is often secondary to the inflammation of adjacent tissue as conjunctiva, nasal cavity and paranasal sinuses, or some special infection are as tuberculosis or syphilis etc.Definite pathogenic factor about dacryocystisis there is no final conclusion so far.But have any to be generally acknowledged, namely lacrimal passage lower end obstruction causes tear storage to stay in lachrymal sac, is the prerequisite causing dacryocystisis.
Chronic dacryocystitis gathers due to pus, wherein often has the bacteria breed that virulence is strong, particularly streptococcus pneumoniae and Hemolytic streptococcus easily to breed.Pus often enters conjunctival sac, causes conjunctiva chronic inflammation; When cornea microtrauma, or carry out intraocular surgery, serpiginous corneal ulcer or suppurative endophthalmitis can be caused.Because the existence of this potential danger, so must treatment in time.
The traditional Chinese medical science claims this sick to be dacryocystitis, to be pent up below the nearly Jingming acupoint of medial canthal because of pyretic toxicity, and burst is red and swollen raised, then a kind of oculopathy of coming to a head of ulceration.Think, primary disease is formed with the functional disorder of the heart closely related, invades, stay in outlet of lacriminal gland outside all wind heat; Or the heart have volt fire, spleen accumulates damp and hot, follow through on attack corner of the eyes portion; Or because of trachoma with the passing of time, evil poison spreads, outlet of lacriminal gland block, be added with on heat in the heart and hold, pyretic toxicity accumulates long-pending, consumption of body fluid by heat QI and blood, store corruption pus form primary disease.
Treat this disease in prior art and usually adopt western medical treatment, mainly contain Drug therapy and operative treatment two kinds.Drug therapy is mainly with sulfanilamide or antibiotic, and through the treatment of a period of time, purulent secretion can disappear, but can not unblocking and retention, easily produces drug dependence.Operative treatment mainly lacrimal passage expands spy art and dacryocystectomy, dacryocystorhinostomy etc., but also there is the shortcomings such as operating difficulties, making patients's misery, damage appearance.
Summary of the invention
For existing current treatment status, the object of the present invention is to provide a kind of Chinese medicine composition for the treatment of chronic dacryocystitis.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of chronic dacryocystitis is made up of endo-medicine and external used medicine.Wherein, endo-medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Plumula Nelumbinis 20-30 part, Radix Arnebiae (Radix Lithospermi) 20-30 part, Radix Stephaniae Epigaeae 10-20 part, Carapax Eretmochelydis 10-20 part, Rhizoma Dioscoreae Septemlobae 10-20 part, Radix Stephaniae Tetrandrae 10-20 part, Faeces Vespertilionis 10-20 part, Herba Senecionis Scandentis 10-20 part, Ramulus Uncariae Cum Uncis 10-20 part, Testa sojae atricolor 10-20 part, Herba Moslae 10-20 part, Scorpio 10-20 part;
External used medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Caulis Trachelospermi 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Folium catalpae bungei 20-30 part, Bombyx mori L. 10-20 part.
Preferably, treat a Chinese medicine composition for chronic dacryocystitis, its endo-medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Plumula Nelumbinis 25 parts, Radix Arnebiae (Radix Lithospermi) 25 parts, Radix Stephaniae Epigaeae 15 parts, Carapax Eretmochelydis 15 parts, Rhizoma Dioscoreae Septemlobae 15 parts, Radix Stephaniae Tetrandrae 15 parts, Faeces Vespertilionis 15 parts, Herba Senecionis Scandentis 15 parts, Ramulus Uncariae Cum Uncis 15 parts, Testa sojae atricolor 15 parts, Herba Moslae 15 parts, Scorpio 15 parts;
Its external used medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Caulis Trachelospermi 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Folium catalpae bungei 25 parts, Bombyx mori L. 15 parts.
Contained by Chinese medicine composition of the present invention, the pharmacological property of each crude drug is as follows.
Plumula Nelumbinis: be the green radicle (Plumula Nelumbinis) in the middle of the mature seed of nymphaeaceae plant lotus.Nature and flavor are bitter, cold.GUIXIN, lung, kidney three warp.Have and clear away heart-fire, reduce phlegm and internal heat, hemostasis, effect of arresting seminal emission.Be used for the treatment of vexed clinically, thirsty, spit blood, seminal emission, gentle QI of five ZANG-organs." this leather is new again " is recorded: " lung-fire, falls in purgation of spleen excess fire for clearing away heart-fire, suppressing the hyperactive liver fire.Relieve summer heat relieving restlessness, promoting the production of body fluid to quench thirst, controls order redness ".
Radix Arnebiae (Radix Lithospermi): be the root of comfrey Radix Arnebiae (Radix Lithospermi), the false Radix Arnebiae (Radix Lithospermi) in Xinjiang-Tibet or Onosma paniculatum.Cold in nature, sweet in the mouth, salty.GUIXIN, Liver Channel.There is the effect of removing heat from blood and promoting blood circulation, heat-clearing and toxic substances removing, laxation relieving constipation.Contain for heat in blood poison clinically, macule purple is black, measles without adequate eruption, skin infection, eczema, burn due to hot liquid or fire.Clearing away heat and cooling blood, for measles, calentura skin eruption, eczema, hematuria, stranguria with blood, dysentery, skin infection, erysipelas, burn, constipation with heat retention.Chang Zuowei hemorrhage, blood-cooling drugs, heat and toxic materials clearing away medicine.
Radix Stephaniae Epigaeae: be the tuber of menispermaceous plants Radix Stephaniae Epigaeae.Bitter in the mouth and pungent, cool in nature, slightly poisonous, can heat-clearing and toxic substances removing, calmness, regulate the flow of vital energy, pain relieving.
Carapax Eretmochelydis: be the carapace of Carapax Eretmochelydis Cheloniidae animal Carapax Eretmochelydis.The property of medicine is sweet, cold; Enter the heart, Liver Channel, have heat-clearing and toxic substances removing, effect of suppressing the hyperactive liver arresting convulsion.
Rhizoma Dioscoreae Septemlobae: the rhizome of herbaceous plant Dioscorea septemloba Thunb. solution of overgrowing for Dioscoreaceae is perennial and powder back of the body Rhizoma Dioscoreae, raw use.Nature and flavor: bitter, are slightly cold.Return liver, stomach warp.Can go turbid by dampness removing, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.
Radix Stephaniae Tetrandrae: be the dry root of menispermaceous plants Radix stephaniae tetrandrae.Nature and flavor: bitter, pungent, cold.Return bladder, kidney, spleen channel.Can wind-damp dispelling, pain relieving, diuretic.Clinically for curing mainly: Fengshi Guanjie pain; Damp and hot limbs pain; Edema; Dysuria; Beriberi damp-edema.
Faeces Vespertilionis: be the feces of vespertilionid Vespertilio etc., dry use.Nature and flavor: pungent, cold.Enter Liver Channel.Can liver heat removing and eyesight improving, dissipating blood stasis removing food stagnancy.Clinically for liver-heat conjunctival congestion, subconjunctival ecchymosis, nyctalopia, inside and outside hide from view and the disease such as infantile malnutrition.
Herba Senecionis Scandentis: be the young young stem and leaf of Compositae herbaceos perennial Herba Senecionis Scandentis.Nature and flavor: bitter are flat.Slightly poisonous.Can heat-clearing and toxic substances removing, liver heat removing and eyesight improving.Be used for the treatment of furuncle toxic swelling clinically, skin eczema, the diseases such as wind-fire acute conjunctivitis.
Ramulus Uncariae Cum Uncis: be the evergreen liana of Rubiaceae wild gambier, Ramulus Uncariae Cum Uncis is used as medicine with the stem branch of buckle, nature and flavor: sweetness and bitterness; Be slightly cold.Return liver, heart channel.There is heat clearing away suppressing the hyperactive liver, effect of relieving spasm by subduing liver-wind.Cure mainly: infantile convulsion; Night cry; Intenseness of heat wind symptom; Eclamposia; Dizziness due to hyperactivity of liver-YANG; Liver-fire distending pain in the head.
Testa sojae atricolor: be the seed coat of Papilionaceae plant teata glycinis.Nature and flavor: sweet are flat.Enter liver, kidney channel.There is the suppressing the hyperactive liver that nourishes blood, heat extraction, effect of hidroschesis.Be used for the treatment of blood-deficiency leading to hyperactivity of the liver, headache wind syndrome of head clinically, have a dizzy spell, the disease such as deficiency-heat, night sweat.
Herba Moslae: for Herba Moslae dry aerial parts are used as medicine, nature and flavor: pungent, tepor.Enter lung, stomach warp.Can diaphoresis expelling summer-heat, row water wet dissipation, during stomach warming is adjusted.Be used for the treatment of acute gastroenteritis, stomachache vomiting and diarrhoea, autumn in summer summer-heat clinically, have a headache and fever, the disease such as aversion to cold is lossless, cholera, edema, epistaxis, halitosis.
Scorpio: also known as Scorpio, sweet in the mouth, pungent, property is put down, poisonous.Can relieving spasm by subduing liver-wind, activating collaterals to relieve pain, detoxicating and resolving stagnation of pathogens.The clinical treatment being usually used in the diseases such as apoplexy, epilepsy, arthromyodynia, encephalitis, headache, pulmonary tuberculosis, scrofula.
Caulis Trachelospermi: be the leaf bine stem of apocynaceae plant trachelospermum jasminoide.Cold nature, bitter in the mouth.GUIXIN, liver, kidney channel.Have expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, clearing away heat and cooling blood, effect of removing toxic substances and promoting subsidence of swelling, cures mainly dispelling wind and removing obstruction in the collateral, and removing heat from blood is subsided a swelling.For beriberoid pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, carbuncle, injury from falling down.
Bombyx mori L.: be the feces excreted after nibbling Mulberry.Color is blackish green, in graininess.There is effect of dispeiling pathogenic wind and removing dampness, heat clearing and blood circulation promoting.Be usually used in treating rheumatism, munbness, joint is unsuccessful, convulsion of sharply vomiting and diarrhoea, and muscles and bones is unsuccessful, blood stasis, wind syndrome of head acute conjunctivitis in lumbar and pedal pain, abdomen.The present invention selects autumn silkworm Bombyx mori L. and late Bombyx mori L. to be used as medicine.
Rhizoma Polygoni Cuspidati: be dry rhizome and the root of polygonaceae plant Rhizoma Polygoni Cuspidati.Nature and flavor: micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.There is heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, effect of relieving cough and resolving phlegm.Be used for the treatment of arthralgia clinically, jaundice due to damp-heat, amenorrhea ， WEIJIA, cough with copious phlegm, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus.
Folium catalpae bungei: be Bignoniaceae plant Chinese catalpa moral blade, nature and flavor: bitter, the Slight Cold, nontoxic.There is effect of detumescence and drawing out poison, evacuation of pus granulation promoting, cure mainly abscess, carbuncle on the back, scrofula, the in vain symptom such as bald.
Present invention also offers a kind of preparation method for the treatment of the Chinese medicine composition of chronic dacryocystitis.
Endo-medicine of the present invention is decoction, and its preparation method is: except Ramulus Uncariae Cum Uncis, will be put in (Faeces Vespertilionis cloth is decocted a drug wrapped and boiled) in marmite by each crude drug for oral administration, and it is appropriate to add clear water, soak 2 hours, add Ramulus Uncariae Cum Uncis after intense fire boils, change slow fire boiling 20 minutes, get filtrate; Add water for second time, after intense fire boils, slow fire boiling 30 minutes again, gets filtrate.Twice filtrate merges and obtains Orally-administered decoction of the present invention; External used medicine of the present invention is fumigation and washing agent, and its preparation method is: decoct with water twice, each 30-40 minute after being pulverized each for external crude drug, merging filtrate and get final product.
During use, endo-medicine needs sooner or later respectively to take 150ml half an hour after meal; Medicine juice need be poured in container by external used medicine, and patient's overlooking surface smokes a 10-15 minute with steam, washes an affected part, then suffer from eye 3-5 minutes, every day 2 times with the gauze piece hot compress of leaching medicinal liquid when temperature is down to and can be tolerated with sterilized cotton ball leaching medicinal liquid.In therapeutic process, fasting is pungent waits irritative food.
The Chinese medicine composition that the present invention treats chronic dacryocystitis is with pharmacology and Chinese medical theory for instructing, according to the pharmacological property scientific composition of pathogen and pathology of tcm and each crude drug, and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Wherein, Plumula Nelumbinis, Radix Arnebiae (Radix Lithospermi) GUIXIN warp in endo-medicine, the heat that can clear away heart-fire, heart-fire is fallen, removing heat from blood goes to be tired of, helps with Radix Stephaniae Epigaeae, Carapax Eretmochelydis heat-clearing and toxic substances removing, Rhizoma Dioscoreae Septemlobae and Radix Stephaniae Tetrandrae compatibility can expelling wind and removing dampness warm, removing obstruction in the collateral to relieve pain.The traditional Chinese medical science is thought, liver opening at eye, and in side, Faeces Vespertilionis, Herba Senecionis Scandentis are Liver Channel blood system medicine, have effect of removing heat from the liver, dissipating blood stasis blood, Ramulus Uncariae Cum Uncis can relieving spasm by subduing liver-wind, heat clearing away suppressing the hyperactive liver, Testa sojae atricolor can heat extraction hidroschesis, nourish blood suppressing the hyperactive liver, four medicines share and cure mainly liver-heat conjunctival congestion, and blood stasis can be made to dissipate, and eyes is clear and bright.Herba Moslae is warm in nature, can diaphoresis and inducing sweat, and can open again lung qi dispersing gas and inducing diuresis to remove edema, rheumatism heresy can be excreted; Scorpio acrid-sweet flavor, other tool wind dispelling, by the merit of heresy, because property is good at walking to alter, has effect of relieving spasm to stop pain, expel wind to dredge collateral, can priming week row whole body with the row efficacy of a drug.Caulis Trachelospermi clearing away heat and cooling blood, removing toxic substances and promoting subsidence of swelling in external used medicine, Bombyx mori L. heat clearing and blood circulation promoting, dispeiling pathogenic wind and removing dampness, Rhizoma Polygoni Cuspidati expelling wind and removing dampness, dissipating blood stasis analgesic therapy, Folium catalpae bungei detumescence and drawing out poison, evacuation of pus granulation promoting.
Chinese medicine composition of the present invention by oral administration and externally with the use for the treatment of, give full play to the speciality of Orally-administered decoction heat-clearing and toxic substances removing, expelling wind and removing dampness, dredge the meridian passage, liver heat removing and eyesight improving, also the outstanding advantages of fumigation and washing agent heat clearing and blood circulation promoting, subduing swelling and detoxicating, evacuation of pus of dispeling the wind more is embodied, play the advantage of both treatment chronic dacryocystitises, compensate for mutual shortcoming.Have the features such as simple for production, cure rate is high, have no side effect, not easily recur, cost is low, clinic is promoted.
Below in conjunction with embodiment, the invention will be further described.
Embodiment one: a kind of Chinese medicine composition for the treatment of chronic dacryocystitis, endo-medicine prescription: Plumula Nelumbinis 20 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Stephaniae Epigaeae 10 grams, Carapax Eretmochelydis 10 grams, Rhizoma Dioscoreae Septemlobae 10 grams, Radix Stephaniae Tetrandrae 10 grams, Faeces Vespertilionis 10 grams, Herba Senecionis Scandentis 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Testa sojae atricolor 10 grams, Herba Moslae 10 grams, Scorpio 10 grams, method of preparation and use: (Faeces Vespertilionis cloth is decocted a drug wrapped and boiled) in marmite will be put in by each crude drug for oral administration except Ramulus Uncariae Cum Uncis, add 500ml cold water and soak 2 hours, Ramulus Uncariae Cum Uncis is added after intense fire boils, change slow fire boiling 20 minutes, get filtrate; Second time 400ml that adds water, after intense fire boils, slow fire boiling 30 minutes again, gets filtrate.Twice filtrate merges and obtains Orally-administered decoction of the present invention; Sooner or later respectively 150ml is taken half an hour after meal;
External used medicine prescription: Caulis Trachelospermi 10 grams, Rhizoma Polygoni Cuspidati 10 grams, Folium catalpae bungei 20 grams, Bombyx mori L. 10 grams, method of preparation and use: decoct with water twice, each 30-40 minute after being pulverized each for external crude drug, merging filtrate and get final product.When external used medicine uses, need pour in container by medicine juice, patient's overlooking surface smokes a 10-15 minute with steam, washes an affected part, then suffer from eye 3-5 minutes, every day 2 times with the gauze piece hot compress of leaching medicinal liquid when temperature is down to and can be tolerated with sterilized cotton ball leaching medicinal liquid.
Embodiment two: a kind of Chinese medicine composition for the treatment of chronic dacryocystitis, endo-medicine prescription: Plumula Nelumbinis 25 grams, Radix Arnebiae (Radix Lithospermi) 25 grams, Radix Stephaniae Epigaeae 15 grams, Carapax Eretmochelydis 15 grams, Rhizoma Dioscoreae Septemlobae 15 grams, Radix Stephaniae Tetrandrae 15 grams, Faeces Vespertilionis 15 grams, Herba Senecionis Scandentis 15 grams, Ramulus Uncariae Cum Uncis 15 grams, Testa sojae atricolor 15 grams, Herba Moslae 15 grams, Scorpio 15 grams, method of preparation and use: (Faeces Vespertilionis cloth is decocted a drug wrapped and boiled) in marmite will be put in by each crude drug for oral administration except Ramulus Uncariae Cum Uncis, add 500ml cold water and soak 2 hours, Ramulus Uncariae Cum Uncis is added after intense fire boils, change slow fire boiling 20 minutes, get filtrate; Second time 400ml that adds water, after intense fire boils, slow fire boiling 30 minutes again, gets filtrate.Twice filtrate merges and obtains Orally-administered decoction of the present invention; Sooner or later respectively 150ml is taken half an hour after meal;
External used medicine prescription: Caulis Trachelospermi 15 grams, Rhizoma Polygoni Cuspidati 15 grams, Folium catalpae bungei 25 grams, Bombyx mori L. 15 grams, method of preparation and use: decoct with water twice, each 30-40 minute after being pulverized each for external crude drug, merging filtrate and get final product.When external used medicine uses, need pour in container by medicine juice, patient's overlooking surface smokes a 10-15 minute with steam, washes an affected part, then suffer from eye 3-5 minutes, every day 2 times with the gauze piece hot compress of leaching medicinal liquid when temperature is down to and can be tolerated with sterilized cotton ball leaching medicinal liquid.
Embodiment three: a kind of Chinese medicine composition for the treatment of chronic dacryocystitis, endo-medicine prescription: Plumula Nelumbinis 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Radix Stephaniae Epigaeae 20 grams, Carapax Eretmochelydis 20 grams, Rhizoma Dioscoreae Septemlobae 20 grams, Radix Stephaniae Tetrandrae 20 grams, Faeces Vespertilionis 20 grams, Herba Senecionis Scandentis 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Testa sojae atricolor 20 grams, Herba Moslae 20 grams, Scorpio 20 grams, method of preparation and use: (Faeces Vespertilionis cloth is decocted a drug wrapped and boiled) in marmite will be put in by each crude drug for oral administration except Ramulus Uncariae Cum Uncis, add 500ml cold water and soak 2 hours, Ramulus Uncariae Cum Uncis is added after intense fire boils, change slow fire boiling 20 minutes, get filtrate; Second time 400ml that adds water, after intense fire boils, slow fire boiling 30 minutes again, gets filtrate.Twice filtrate merges and obtains Orally-administered decoction of the present invention; Sooner or later respectively 150ml is taken half an hour after meal;
External used medicine prescription: Caulis Trachelospermi 20 grams, Rhizoma Polygoni Cuspidati 20 grams, Folium catalpae bungei 30 grams, Bombyx mori L. 20 grams, method of preparation and use: decoct with water twice, each 30-40 minute after being pulverized each for external crude drug, merging filtrate and get final product.When external used medicine uses, need pour in container by medicine juice, patient's overlooking surface smokes a 10-15 minute with steam, washes an affected part, then suffer from eye 3-5 minutes, every day 2 times with the gauze piece hot compress of leaching medicinal liquid when temperature is down to and can be tolerated with sterilized cotton ball leaching medicinal liquid.
Below in conjunction with acute oral toxicity test and acute skin irritation test, the toxicity of endo-medicine of the present invention and the zest of external used medicine are explained.
One, acute oral toxicity test report.
1, experiment purpose: endo-medicine of the present invention is to the acute oral toxicity effect of mice and intensity.
2, materials and methods:
(1) tested material: endo-medicine of the present invention; Character: pitchy decoction;
(2) sample pre-treatments: prepare sample by above-described embodiment 2 prescription and preparation method;
(3) experimental animal: one grade of Kunming mouse, 20, female, hero half and half, body weight 18-22 gram; Cure special Experimental Animal Center by Shandong to provide.
3, test method: (maximum limit is mensuration)
Select healthy adult mice 20, body weight 18-22 gram, female, hero half and half, dose design is female is 6000m part/k part BW, and male is 6000m part/k part BW, gives tested material by 0.1ml/10 part BW per os gavage.Before gavage, animal fasting 12 hours, freely drinks water.Give normal diet after gavage, observe two weeks, record poisoning symptom and death condition.
4, result of the test:
In 14 day observation period, animal subject reaction without exception, without dead, postmortem no abnormality seen.Female, male mice acute oral LD50 is greater than 5000m part/k part/BW.
5, experiment conclusion:
Judge according to acute toxicity grading criteria in " disinfection technology standard " (1999), the nontoxic level in the true border of endo-medicine of the present invention.
Two, acute skin irritation test report.
1, experiment purpose: detect external fumigation and washing agent of the present invention to the stimulation/corrosiveness of laboratory animal skin and intensity.
2, materials and methods:
(1) tested material: external used medicine of the present invention; Character: yellowish-brown decoction;
(2) laboratory animal: one grade of large ear white race rabbit, 4, female, body weight 2.1-2.3 kilogram; Cure special Experimental Animal Center by Shandong to provide.
3, test method:
The healthy family selecting skin intact exempts from 4, within first 24 hours, is cut its spinal column both sides, back by hair in test, the left and right each about 3cm × 3cm of unhairing area.Get the agent of tested material external fumigation and washing during test and carry out hot smoking 10-15 minute to skin of unhairing, and get two layers of gauze of the 2.5cm × 2.5cm of leaching tested material medicinal liquid, be applied to skin of unhairing surface, side, oilpaper covers, immobilization with adhesive tape.Opposite side skin is as blank.Close after 4 hours, dismantle, and go residual tested material with warm water cleaning, within 1,24 and 48 hour after removing tested material, observe and smear position dermoreaction, and mark.
4, experimental result: any erythema does not appear in laboratory animal skin, red and swollen, inflammation phenomenon.
5, experiment conclusion: judge according to skin wound repair standards of grading in " disinfection technology standard " (1999), external application of the present invention belongs to nonirritant to animal skin stimulus intensity.
The effectiveness of below in conjunction with clinical data, the present invention being treated to the Chinese medicine composition of chronic dacryocystitis is explained.
One, data and method.
1, clinical data: hospital outpatient is accepted for medical treatment and made a definite diagnosis chronic dacryocystitis patient 48 example, wherein, man 26 example, female 22 example; Adult 35 example, child 13 example.
2, Therapeutic Method: take the Chinese medicine composition that the present invention treats chronic dacryocystitis.Wherein endo-medicine potion on the one, respectively takes 150ml sooner or later after meal half an hour.When external used medicine uses, poured into by medicine juice in container, patient's overlooking surface smokes a 10-15 minute with steam, washes an affected part, then suffer from eye 3-5 minutes, every day 2 times with the gauze piece hot compress of leaching medicinal liquid when temperature is down to and can be tolerated with sterilized cotton ball leaching medicinal liquid.It within 7th, is a course for the treatment of.
Two, clinical effectiveness.
1, criterion of therapeutical effect: be divided into effective, effective and invalid three classes according to the degree that symptom, Signs are improved:
Effective: clinical symptoms all disappears, within more than 1 year, do not recur;
Effective: clinical symptoms takes a turn for the better or partial disappearance;
Invalid: clinical symptoms is unchanged even to be increased the weight of.
2, therapeutic outcome: through 1-2 course of therapy, in 48 routine patients, effective 37 examples, account for 77.08%, effective 11 examples, and 22.92%, invalid 0 example, total effective rate 100%.
Three, model case.
1, Zhang, female, 65 years old, right eye suffered from chronic dacryocystitis 3 years, repeatedly sheds tears, visible a large amount of purulent secretion.Take traditional Chinese medicine composition for treating of the present invention, endo-medicine: Plumula Nelumbinis 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Radix Stephaniae Epigaeae 20 grams, Carapax Eretmochelydis 20 grams, Rhizoma Dioscoreae Septemlobae 20 grams, Radix Stephaniae Tetrandrae 20 grams, Faeces Vespertilionis 20 grams, Herba Senecionis Scandentis 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Testa sojae atricolor 20 grams, Herba Moslae 20 grams, Scorpio 20 grams; External used medicine: Caulis Trachelospermi 20 grams, Rhizoma Polygoni Cuspidati 20 grams, Folium catalpae bungei 30 grams, Bombyx mori L. 20 grams.After the course for the treatment of, symptom obviously alleviates, continue with one the course for the treatment of transference cure and healing, follow up a case by regular visits to and do not recur for 1 year.
2, Ma, man, 48 years old, left eye is red and swollen, repeatedly shed tears, visible purulent secretion, be diagnosed as chronic dacryocystitis, use treatment by Chinese herbs of the present invention, endo-medicine: Plumula Nelumbinis 20 grams, Radix Arnebiae (Radix Lithospermi) 20 grams, Radix Stephaniae Epigaeae 10 grams, Carapax Eretmochelydis 10 grams, Rhizoma Dioscoreae Septemlobae 10 grams, Radix Stephaniae Tetrandrae 10 grams, Faeces Vespertilionis 10 grams, Herba Senecionis Scandentis 10 grams, Ramulus Uncariae Cum Uncis 10 grams, Testa sojae atricolor 10 grams, Herba Moslae 10 grams, Scorpio 10 grams; External used medicine: Caulis Trachelospermi 10 grams, Rhizoma Polygoni Cuspidati 10 grams, Folium catalpae bungei 20 grams, Bombyx mori L. 10 grams.Treat the symptom recovery from illness course for the treatment of, consolidate and take a course for the treatment of, follow up a case by regular visits to and do not recur half a year.
3, land so-and-so, man, 71 years old, suffers from chronic dacryocystitis 1 year, take traditional Chinese medicine composition for treating of the present invention, endo-medicine: Plumula Nelumbinis 30 grams, Radix Arnebiae (Radix Lithospermi) 30 grams, Radix Stephaniae Epigaeae 20 grams, Carapax Eretmochelydis 20 grams, Rhizoma Dioscoreae Septemlobae 20 grams, Radix Stephaniae Tetrandrae 20 grams, Faeces Vespertilionis 20 grams, Herba Senecionis Scandentis 20 grams, Ramulus Uncariae Cum Uncis 20 grams, Testa sojae atricolor 20 grams, Herba Moslae 20 grams, Scorpio 20 grams; External used medicine: Caulis Trachelospermi 20 grams, Rhizoma Polygoni Cuspidati 20 grams, Folium catalpae bungei 30 grams, Bombyx mori L. 20 grams.Take height red, swollen, hot remission in lachrymal sac portion after 3 days, disappear after 7 days, after taking 2 courses for the treatment of, chronic dacryocystitis disease has good alleviation, after continuing to strengthen 1 course for the treatment of, and recovery from illness.
Claims (3)
1. treat the Chinese medicine composition of chronic dacryocystitis for one kind, it is characterized in that, described compositions is made up of endo-medicine and external used medicine, and described endo-medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Plumula Nelumbinis 20-30 part, Radix Arnebiae (Radix Lithospermi) 20-30 part, Radix Stephaniae Epigaeae 10-20 part, Carapax Eretmochelydis 10-20 part, Rhizoma Dioscoreae Septemlobae 10-20 part, Radix Stephaniae Tetrandrae 10-20 part, Faeces Vespertilionis 10-20 part, Herba Senecionis Scandentis 10-20 part, Ramulus Uncariae Cum Uncis 10-20 part, Testa sojae atricolor 10-20 part, Herba Moslae 10-20 part, Scorpio 10-20 part; Described external used medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Caulis Trachelospermi 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Folium catalpae bungei 20-30 part, Bombyx mori L. 10-20 part.
2. a kind of Chinese medicine composition for the treatment of chronic dacryocystitis according to claim 1, described endo-medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Plumula Nelumbinis 25 parts, Radix Arnebiae (Radix Lithospermi) 25 parts, Radix Stephaniae Epigaeae 15 parts, Carapax Eretmochelydis 15 parts, Rhizoma Dioscoreae Septemlobae 15 parts, Radix Stephaniae Tetrandrae 15 parts, Faeces Vespertilionis 15 parts, Herba Senecionis Scandentis 15 parts, Ramulus Uncariae Cum Uncis 15 parts, Testa sojae atricolor 15 parts, Herba Moslae 15 parts, Scorpio 15 parts; Described external used medicine is made up of the raw material of Chinese medicine of following weight parts proportioning: Caulis Trachelospermi 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Folium catalpae bungei 25 parts, Bombyx mori L. 15 parts.
3. the Chinese medicine composition for the treatment of chronic dacryocystitis according to claim 1 and 2, is characterized in that, described endo-medicine is decoction; Described external used medicine is fumigation and washing agent.
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| CN101152343A (en) * | 2007-09-20 | 2008-04-02 | 吴月 | Traditional Chinese medicine for treating chronic dacryocystitis |
| CN101797332A (en) * | 2010-04-15 | 2010-08-11 | 滕淑玲 | Traditional Chinese medicine for treating chronic dacryocystitis and preparation method thereof |
| CN102366561A (en) * | 2011-09-28 | 2012-03-07 | 邓华伦 | Chinese herbal medicine for treating acute and chronic dacryocystitis |
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| CN101152343A (en) * | 2007-09-20 | 2008-04-02 | 吴月 | Traditional Chinese medicine for treating chronic dacryocystitis |
| CN101797332A (en) * | 2010-04-15 | 2010-08-11 | 滕淑玲 | Traditional Chinese medicine for treating chronic dacryocystitis and preparation method thereof |
| CN102366561A (en) * | 2011-09-28 | 2012-03-07 | 邓华伦 | Chinese herbal medicine for treating acute and chronic dacryocystitis |
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