CN105232754A - Medicine for treating type-II diabetes - Google Patents
Medicine for treating type-II diabetes Download PDFInfo
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- CN105232754A CN105232754A CN201510794356.1A CN201510794356A CN105232754A CN 105232754 A CN105232754 A CN 105232754A CN 201510794356 A CN201510794356 A CN 201510794356A CN 105232754 A CN105232754 A CN 105232754A
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Abstract
The invention relates to a medicine for treating type-II diabetes. The medicine is prepared from the following raw medicinal materials in parts by weight: 10 parts of milkvetch root, 11 parts of rehmannia root, 8 parts of chaulmoogratree seed, 6 parts of radix knoxiae, 6 parts of longtube ground ivy herb, 5 parts of scabrous elephantfoot herb, 7 parts of phyllanthus ruinaria, and 8 parts of bittersweet herb. The medicine uses the milkvetch root for invigorating qi to strengthen superficial body resistance, the rehmannia root for clearing away heat and promoting salivation, the chaulmoogratree seed for dispelling pathogenic wind and removing dampness, the radix knoxiae for removing water retention by purgation, the longtube ground ivy herb for clearing away heat and toxic materials, the scabrous elephantfoot herb for relieving epigastric distention and depressing qi, the phyllanthus ruinaria for clearing away heat and inducing diuresis, and the bittersweet herb for clearing away heat and toxic materials. All the medicinal materials are used together to achieve the effects of invigorating qi to strengthen superficial body resistance and clearing away heat to promote salivation, thereby effectively treating the treating type-II diabetes. A clinical experiment proves that the medicine provided by the invention can be used for treating the treating type-II diabetes safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of medicine being used for the treatment of type Ⅱdiabetes mellitus.
Background technology
Type Ⅱdiabetes mellitus original name, Adult Onset's patients with type Ⅰ DM, how the sequela of 35 ~ 40 years old, accounts for diabetics more than 90%.
In type Ⅱdiabetes mellitus, a part of patient is based on insulin resistant clinically, and how fat patient is, because of insulin resistant, insulin sensitivity declines, in blood, insulin increases to compensate its insulin resistant, but the hyperglycemia of relative patient, insulin secretion is relative deficiency still.This type of patient's early symptom is not obvious, only has slightly weak, thirsty, is everlasting before clarifying a diagnosis and just trunk and microvascular complication can occurs.Diet Therapy and oral antidiabetic drug is many can be effective.Another part patient, based on defect of insulin secretion, needs supplemented with exogenous insulin clinically.
Common 1. oral antidiabetic drug of current doctor trained in Western medicine clinical treatment type Ⅱdiabetes mellitus medicine: 1) biguanides (as metformin); 2) sulphanylureas (as glimepiride, glibenclamide, gliclazide and gliquidone); 3) thiazolidinediones (as rosiglitazone and pioglitazone); 4) benzoic acid derivative class (as repaglinide and Nateglinide); 5) alpha-glucosidase inhibitor (as acarbose and voglibose).2. trypsin class medicine.
Medical material involved in the present invention is recorded in all as seen " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of type Ⅱdiabetes mellitus, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing type Ⅱdiabetes mellitus.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of medicine being used for the treatment of type Ⅱdiabetes mellitus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 10 parts, Radix Rehmanniae 11 parts, Semen Hydnocarpi 8 parts, Radix Knoxiae 6 parts, Herba Glechomae 6 parts, Herba Elephantopi scaberis 5 parts, Cacumen Securinegae Suffruticosae 7 parts, Herba Solani Lyrati 8 parts.
Inventor thinks: pancreas is three burnt cradles, warm the five internal organs, main Tibetan meaning.The five internal organs have to suffer from reversiblely hinders pancreas, and wherein again with deficiency of kidney-YIN, lung dryness of the stomach heat is main.Invigorating QI to consolidate the body surface resistance, clearing away heat and promoting production of body fluid is noted in treatment.
The present invention uses: Radix Astragali invigorating QI to consolidate the body surface resistance; Radix Rehmanniae clearing away heat and promoting production of body fluid; Semen Hydnocarpi dispeiling pathogenic wind and removing dampness; Radix Knoxiae removing fluid-retention by purgation; Herba Glechomae heat-clearing and toxic substances removing; The Herba Elephantopi scaberis alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards; Cacumen Securinegae Suffruticosae clearing away heat and promoting diuresis; Herba Solani Lyrati heat-clearing and toxic substances removing.All medicines share, and play effect of invigorating QI to consolidate the body surface resistance, clearing away heat and promoting production of body fluid altogether, effectively treat type Ⅱdiabetes mellitus.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects patients with NIDDM 80 example for 2012 altogether between year December of December ~ 2014, all from department of endocrinology outpatient service, and 38 ~ 70 years old age, male 45 example, women 35 example.The course of disease 2 ~ 10 years.
Diagnostic criteria: the DM clinical criteria that health organization (WHO) is formulated for 1999
1. diabetes typical case three-many-one-little symptom adds blood glucose (FPG) >=11.1mmo ~ L at any time; 2. fasting glucose >=7.0mmo ~ L; 3. two hours blood glucoses during 0GITI1 >=11.1mmo ~ L.What twice diagnosis all met one of above-mentioned condition can be considered diabetics.
Meet above-mentioned diagnostic criteria, the patient that the age is greater than 18 years old.
Exclusion standard: trimester of pregnancy, women breast-feeding their children; Merge serious cardiopulmonary hepatorenal disease person.
2, test method
The decoct that the oral the present invention of all patients obtains according to embodiment 1, every day 3 times.2 weeks courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Judge according to " diagnosis of type Ⅱdiabetes mellitus disease and efficacy assessment standard ".
1. patient blood glucose recover normally, clinical symptom disappearance and continue more than three months persons for effective;
2. patient blood glucose recovers normally, the clinical symptoms person of having clear improvement is effective;
3. patient blood glucose recover normally, clinical symptoms be improved or without deterioration person for stable disease;
4. the abnormal also clinical symptoms of patient blood glucose is invalid without improving or adding severe one.
3.2 therapeutic outcome
The effective example 42 of 80 routine patient, effective 21 examples, stablize 13 examples, invalid 4 examples, total effective rate 95%.There is laxativeness in treatments period 2 example, has no other obvious adverse reaction.It is safe and effective that visible the present invention is used for the treatment of type Ⅱdiabetes mellitus, has the value applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: the Radix Astragali 10 grams, Radix Rehmanniae 11 grams, Semen Hydnocarpi 8 grams, Radix Knoxiae 6 grams, Herba Glechomae 6 grams, Herba Elephantopi scaberis 5 grams, Cacumen Securinegae Suffruticosae 7 grams, Herba Solani Lyrati 8 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of type Ⅱdiabetes mellitus.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: the Radix Astragali 10 grams, Radix Rehmanniae 11 grams, Semen Hydnocarpi 8 grams, Radix Knoxiae 6 grams, Herba Glechomae 6 grams, Herba Elephantopi scaberis 5 grams, Cacumen Securinegae Suffruticosae 7 grams, Herba Solani Lyrati 8 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of type Ⅱdiabetes mellitus.Oral, daily once.
Embodiment 3
Take: the Radix Astragali 10 grams, Radix Rehmanniae 11 grams, Semen Hydnocarpi 8 grams, Radix Knoxiae 6 grams, Herba Glechomae 6 grams, Herba Elephantopi scaberis 5 grams, Cacumen Securinegae Suffruticosae 7 grams, Herba Solani Lyrati 8 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of type Ⅱdiabetes mellitus.Oral, every bu is taken for twice sooner or later.
Claims (4)
1. one kind is used for the treatment of the medicine of type Ⅱdiabetes mellitus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: the Radix Astragali 10 parts, Radix Rehmanniae 11 parts, Semen Hydnocarpi 8 parts, Radix Knoxiae 6 parts, Herba Glechomae 6 parts, Herba Elephantopi scaberis 5 parts, Cacumen Securinegae Suffruticosae 7 parts, Herba Solani Lyrati 8 parts.
2. be used for the treatment of the medicine of type Ⅱdiabetes mellitus as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 10 parts, Radix Rehmanniae 11 parts, Semen Hydnocarpi 8 parts, Radix Knoxiae 6 parts, Herba Glechomae 6 parts, Herba Elephantopi scaberis 5 parts, Cacumen Securinegae Suffruticosae 7 parts, Herba Solani Lyrati 8 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the medicine of type Ⅱdiabetes mellitus as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 10 parts, Radix Rehmanniae 11 parts, Semen Hydnocarpi 8 parts, Radix Knoxiae 6 parts, Herba Glechomae 6 parts, Herba Elephantopi scaberis 5 parts, Cacumen Securinegae Suffruticosae 7 parts, Herba Solani Lyrati 8 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the medicine of type Ⅱdiabetes mellitus as claimed in claim 1, it is characterized in that, its preparation method is: take: the Radix Astragali 10 parts, Radix Rehmanniae 11 parts, Semen Hydnocarpi 8 parts, Radix Knoxiae 6 parts, Herba Glechomae 6 parts, Herba Elephantopi scaberis 5 parts, Cacumen Securinegae Suffruticosae 7 parts, Herba Solani Lyrati 8 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510794356.1A CN105232754A (en) | 2015-11-17 | 2015-11-17 | Medicine for treating type-II diabetes |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510794356.1A CN105232754A (en) | 2015-11-17 | 2015-11-17 | Medicine for treating type-II diabetes |
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| CN105232754A true CN105232754A (en) | 2016-01-13 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109157558A (en) * | 2018-11-01 | 2019-01-08 | 郑老海 | A kind of Chinese medicine and preparation method thereof for treating diabetes |
| CN116808097A (en) * | 2023-06-30 | 2023-09-29 | 云南中医药大学 | Euphorbia pekinensis extract with hypoglycemic activity and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698131A (en) * | 2012-05-07 | 2012-10-03 | 王伟 | Capsule for treating diabetes mellitus |
| CN103356885A (en) * | 2013-08-09 | 2013-10-23 | 李春华 | Medicine for treating diabetes |
-
2015
- 2015-11-17 CN CN201510794356.1A patent/CN105232754A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102698131A (en) * | 2012-05-07 | 2012-10-03 | 王伟 | Capsule for treating diabetes mellitus |
| CN103356885A (en) * | 2013-08-09 | 2013-10-23 | 李春华 | Medicine for treating diabetes |
Non-Patent Citations (1)
| Title |
|---|
| 杨丽敏: "自拟降糖饮治疗Ⅱ型糖尿病38例", 《中医药信息》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109157558A (en) * | 2018-11-01 | 2019-01-08 | 郑老海 | A kind of Chinese medicine and preparation method thereof for treating diabetes |
| CN116808097A (en) * | 2023-06-30 | 2023-09-29 | 云南中医药大学 | Euphorbia pekinensis extract with hypoglycemic activity and application thereof |
| CN116808097B (en) * | 2023-06-30 | 2024-02-20 | 云南中医药大学 | Euphorbia pekinensis extract with hypoglycemic activity and application thereof |
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Application publication date: 20160113 |