CN105188736A - 胰岛素给药方案 - Google Patents

胰岛素给药方案 Download PDF

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Publication number
CN105188736A
CN105188736A CN201480016936.1A CN201480016936A CN105188736A CN 105188736 A CN105188736 A CN 105188736A CN 201480016936 A CN201480016936 A CN 201480016936A CN 105188736 A CN105188736 A CN 105188736A
Authority
CN
China
Prior art keywords
insulin
long
acting insulin
chain
acting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201480016936.1A
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English (en)
Chinese (zh)
Inventor
T.乔汉森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of CN105188736A publication Critical patent/CN105188736A/zh
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN201480016936.1A 2013-03-20 2014-03-19 胰岛素给药方案 Withdrawn CN105188736A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP13160194 2013-03-20
EP13160194.0 2013-03-20
US201361804363P 2013-03-22 2013-03-22
US61/804363 2013-03-22
PCT/EP2014/055533 WO2014147141A1 (en) 2013-03-20 2014-03-19 Insulin dosing regimen

Publications (1)

Publication Number Publication Date
CN105188736A true CN105188736A (zh) 2015-12-23

Family

ID=47900938

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480016936.1A Withdrawn CN105188736A (zh) 2013-03-20 2014-03-19 胰岛素给药方案

Country Status (5)

Country Link
US (4) US20160296602A1 (enExample)
EP (1) EP2976096B1 (enExample)
JP (1) JP6755175B2 (enExample)
CN (1) CN105188736A (enExample)
WO (1) WO2014147141A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090074882A1 (en) 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
ES2607003T3 (es) 2008-10-30 2017-03-28 Novo Nordisk A/S Tratamiento de diabetes mellitus utilizando inyecciones de insulina con una frecuencia de inyección inferior a la diaria
HRP20191793T1 (hr) 2010-10-27 2019-12-27 Novo Nordisk A/S Liječenje dijabetesa melitusa injekcijama inzulina koje se primijenjuje u različitim intervalima injiciranja
JP2016519127A (ja) 2013-04-30 2016-06-30 ノヴォ ノルディスク アー／エス 新規投与レジメン
US11673933B2 (en) 2016-11-28 2023-06-13 Novo Nordisk A/S Method for using insulin degludec for the improvement of glycemic control and reduction of acute and long-term diabetes complications
US11278596B2 (en) 2016-11-28 2022-03-22 Novo Nordisk A/S Insulin degludec in cardiovascular conditions
WO2018096164A1 (en) * 2016-11-28 2018-05-31 Novo Nordisk A/S Insulin degludec for treating diabetes
CA3051639A1 (en) 2017-02-01 2018-08-09 Novo Nordisk A/S Procoagulant antibodies
JOP20190273A1 (ar) 2017-05-26 2019-11-24 Lilly Co Eli مركب إنسولين معالج بأسيل
AR112015A1 (es) 2017-06-09 2019-09-11 Novo Nordisk As Composiciones sólidas para administración oral
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US20220023391A1 (en) * 2018-06-26 2022-01-27 Novo Nordisk A/S System providing dose recommendations for basal insulin titration
US11220554B2 (en) 2018-09-07 2022-01-11 Novo Nordisk A/S Procoagulant antibodies
CA3122636A1 (en) 2018-12-11 2020-06-18 Sanofi Insulin analogs having reduced insulin receptor binding affinity
JP7518149B2 (ja) 2019-07-12 2024-07-17 ノヴォ ノルディスク アー／エス 高濃度インスリン製剤

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101454019A (zh) * 2006-04-12 2009-06-10 百达尔公司 速效和长效胰岛素联合制剂
CN101955527A (zh) * 2003-08-05 2011-01-26 诺沃挪第克公司 新型胰岛素衍生物
CN102319422A (zh) * 2010-05-19 2012-01-18 赛诺菲-安万特 长效胰岛素制剂

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4463814B2 (ja) * 2003-08-05 2010-05-19 ノボ ノルディスク アクティーゼルスカブ 新規のインスリン誘導体
US20090074882A1 (en) * 2005-12-28 2009-03-19 Novo Nordisk A/S Insulin compositions and method of making a composition
WO2008152106A1 (en) * 2007-06-13 2008-12-18 Novo Nordisk A/S Pharmaceutical formulation comprising an insulin derivative
EP2178910B1 (en) * 2007-08-15 2014-10-08 Novo Nordisk A/S Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids
ES2607003T3 (es) * 2008-10-30 2017-03-28 Novo Nordisk A/S Tratamiento de diabetes mellitus utilizando inyecciones de insulina con una frecuencia de inyección inferior a la diaria
WO2011141407A1 (en) * 2010-05-10 2011-11-17 Novo Nordisk A/S Process for the preparation of insulin-zinc complexes
PL2632478T3 (pl) * 2010-10-27 2020-03-31 Novo Nordisk A/S Leczenie cukrzycy z zastosowaniem zastrzyków insuliny podawanych w różnych odstępach czasu
MX342922B (es) * 2011-02-01 2016-10-19 Novo Nordisk As Purificacion de insulina.
CN105749253A (zh) * 2011-03-01 2016-07-13 Jds治疗有限公司 用于预防和治疗糖尿病、低血糖症及相关病症的胰岛素和铬组合物
EP2844274B1 (en) * 2012-05-01 2019-03-20 Novo Nordisk A/S Pharmaceutical composition
JP2016519127A (ja) * 2013-04-30 2016-06-30 ノヴォ ノルディスク アー／エス 新規投与レジメン

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101955527A (zh) * 2003-08-05 2011-01-26 诺沃挪第克公司 新型胰岛素衍生物
CN101454019A (zh) * 2006-04-12 2009-06-10 百达尔公司 速效和长效胰岛素联合制剂
CN102319422A (zh) * 2010-05-19 2012-01-18 赛诺菲-安万特 长效胰岛素制剂

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FEI WANG, ET AL.: "Insulin degludec as an ultralong-acting basal insulin once a day: a systematic review", 《DIABETES METAB SYNDR OBES.》 *
TIM HEISE, ET AL.: "Insulin Degludec 200 U/mL is Ultra-long Acting and has a Flat and Stable Glucose-lowering Effect", 《CAN J DIABETES》 *

Also Published As

Publication number Publication date
JP6755175B2 (ja) 2020-09-16
US20220152160A1 (en) 2022-05-19
US20170319664A1 (en) 2017-11-09
EP2976096B1 (en) 2019-02-27
US20190160155A1 (en) 2019-05-30
US20160296602A1 (en) 2016-10-13
WO2014147141A1 (en) 2014-09-25
JP2016516076A (ja) 2016-06-02
EP2976096A1 (en) 2016-01-27

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Legal Events

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PB01 Publication
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SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication

Application publication date: 20151223

WW01 Invention patent application withdrawn after publication