CN105169119A - Rabbit heat stress fighting oral solution and preparation method thereof - Google Patents
Rabbit heat stress fighting oral solution and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a rabbit heat stress fighting oral solution prepared from astragalus, honeysuckle flower, solallum nigrum L.ver pauciflorum liou, gypsum, coptis chinensis, white atractylodes rhizome, radix rehmanniae, semen euryales, reed rhizome, cortex lycii radicis, humulus japonicus, semen platycladi, malt, cyclodextrin, tea polyphenols and a preservative. The invention also discloses a preparation method of the rabbit heat stress fighting oral solution. According to the pathogenic mechanism of rabbit heat stress, all the crude drugs take a synergistic effect, so that the physiological metabolism is comprehensively coordinated, the effects of clearing away heat and toxic materials, inducing diuresis to alleviate thirst, tonifying the spleen and appetizing as well as improving the immunological function of a body are simultaneously taken, the appetite and daily gain of a rabbit are increased, the death rate is reduced, defects of a single component are overcome, and the rabbit heat stress fighting effect is excellent. The rabbit heat stress fighting oral solution has the advantages of simple preparation process, convenient sampling and use, low cost, no drug residues and toxic or side effects and good effect, and is an environment-friendly rabbit heat stress fighting traditional Chinese medicine preparation.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation technical field, be specifically related to a kind of easy to use, effective, anti-rabbit heat stress oral liquid that cost is low and preparation method thereof.
Background technology
Heat stress refers to that animal body is for being unfavorable for the summation that the nonspecific response that its physiological high ambient temperature produces reacts.The normal temperature of rabbit is 38.3-39.5 DEG C, and the bodily form is little, and metabolism is vigorous, and in body, heat production is many, and its fur is thicker simultaneously, and sweat gland is less, so the impact that summer high temperature is produced rabbit is more remarkable than other domestic animal.Along with the continuous aggravation of global climate greenhouse effect, the annual summer high temperature weather of China's most area, for up to 3-4 month, makes rabbit occur obvious heat stress.When rabbit is in heat stress, body, in order to strengthen heat radiation, suppresses exothermal process, and the secretion of Digestive system and gastrointestinal motility function are declined, and substance metabolism level declines, and causes the body weight gains of rabbit to reduce.In southern high-temperature height Humid Area, heat stress can make rabbit fertility performance significantly decline.
Heat stress changes various physiology, the biochemical reaction of rabbit, and clinical manifestation is lassitude, loss of appetite, accelerated breathing, and body temperature raises, poor growth, and immunity reduces even dead, causes serious economic loss to rabbit keeping.At present, research worker is studied rabbit anti-heat stress, but mainly rests on function of environment heat emission, and the anti-stress such as multidimensional, electrolyte additive of throwing something and feeding, effect is undesirable.
Summary of the invention
The present invention, according to the deficiencies in the prior art, provides a kind of anti-rabbit heat stress oral liquid, alleviates the thermal stress reaction of rabbit in summer high temperature environment, improves appetite and the daily gain of rabbit, reduces mortality rate.
Another object of the present invention is to provide a kind of preparation method of anti-rabbit heat stress oral liquid.
The object of the invention is to be achieved through the following technical solutions:
A kind of anti-rabbit heat stress oral liquid, is made up of the raw material of following weight portion: Radix Astragali 20-50 part, Flos Lonicerae 20-50 part, crow select rule 10-25 part, Gypsum Fibrosum 20-50 part, Rhizoma Coptidis 15-30 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Radix Rehmanniae 10-30 part, Semen Euryales 5-15 part, Rhizoma Phragmitis 10-30 part, Cortex Lycii 20-50 part, Herba humuli scandentis 10-30 part, Semen Platycladi 10-30 part, Fructus Hordei Germinatus 10-40 part, cyclodextrin 10-60 part, tea polyphenols 50-70 part, antiseptic 0.02-0.4 part.
Preferably, a kind of anti-rabbit heat stress oral liquid, is made up of the raw material of following weight portion: the Radix Astragali 30 parts, Flos Lonicerae 30 parts, crow select 18 parts, rule, Gypsum Fibrosum 30 parts, Rhizoma Coptidis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 20 parts, the Radix Rehmanniae, Semen Euryales 10 parts, Rhizoma Phragmitis 20 parts, Cortex Lycii 30 parts, Herba humuli scandentis 20 parts, Semen Platycladi 20 parts, 30 parts, Fructus Hordei Germinatus, cyclodextrin 30 parts, tea polyphenols 60 parts, antiseptic 0.2 part.
Described, cyclodextrin is the one in beta-schardinger dextrin-, methyl-B-cyclodextrin, carboxymethyl-beta-cyclodextrin, HP-β-CD.
A preparation method for anti-rabbit heat stress oral liquid, comprises the following steps:
1) each raw material is taken by weight;
2) Radix Astragali, Flos Lonicerae, Wu Diangui, Gypsum Fibrosum, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Semen Euryales, Rhizoma Phragmitis, Cortex Lycii, Herba humuli scandentis, Semen Platycladi and maltcrusher are pulverized, cross 60-80 mesh sieve, obtain raw material 1;
3) by cyclodextrin and raw material 1 mix homogeneously, purified water is added by the weight ratio of 1:8-20, soak 0.5-1h, be heated to 50-90 DEG C, under 300-500W condition, multifunction supersonic extractor supersound extraction 0.25-1.5h, extract 2-3 time, merge extractive liquid, filter, be evaporated to the weight of 5 times of raw materials 1, obtain filtrate;
4) tea polyphenols and antiseptic are added in filtrate, stir, 100 DEG C of steam sterilization 0.25h, fill, anti-rabbit heat stress oral liquid of the present invention can be obtained.
Using method: use drinking water dilution rabbit heat stress oral liquid in 1:10-20 times of ratio under summer high temperature environment condition, allow rabbit freely drink, be used in conjunction 5-10 days.
In prescription of the present invention, each component pharmacological effect is as follows:
The Radix Astragali: sweet in the mouth, slightly warm in nature.Return lung, spleen, liver, kidney channel.Modern medicine study shows, the Radix Astragali has enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.Jishengshenqiwan albuminuria can be eliminated, strengthen myocardial contraction, regulate blood sugar content.The Radix Astragali can not only coronary artery dilator, improves blood supply of cardiac muscle, improves immunologic function, and can the process of delaying cell aging.
Flos Lonicerae: cold in nature, sweet in the mouth.Return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, antiinflammatory, tonify deficiency treat wind.For disease, epidemic febrile disease heating under distension, pyretic toxicity carbuncle and ulcer and tumor.
Crow point rule: mildly bitter flavor, sweet, cold in nature.Return liver, lung, kidney, warp.Clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.For dysentery, hypertension, jaundice, tonsillitis, cough due to lung-heat, gingival hemorrhage.External treatment skin noxious dampness, black bleb, mouse are bitten.
Gypsum Fibrosum: pungent, sweet, is slightly cold.Attach to the lung and stomach meridians.Clearing away heat-fire, relieving restlessness is quenched the thirst, convergence granulation promoting.
Rhizoma Coptidis: bitter in the mouth, cold in nature.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
The Radix Rehmanniae: sweet in the mouth, cold in nature.GUIXIN, liver, kidney channel.Control fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon hinders constipation.
Semen Euryales: sweet in the mouth, puckery, property is put down.Return spleen, kidney channel.Supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, eliminating dampness and arresting leucorrhea.For emission and spermatorrhea, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.
Rhizoma Phragmitis: sweet in the mouth, cold in nature.Attach to the lung and stomach meridians.Clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastropyretic vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Cortex Lycii: sweet in the mouth, cold in nature.Return lung, liver, kidney channel.Removing heat from blood removes and steams, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis.Interior-heat is quenched one's thirst.
Herba humuli scandentis: sweet in the mouth, hardship, cold in nature.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.For pulmonary tuberculosis hectic fever, gastroenteritis, dysentery, cold, fever, dysuria, pyelonephritis, acute nephritis, cystitis, urinary system calculus; Carbuncle furuncle and phyma poison is controlled in external, eczema, venom.
Semen Platycladi: sweet in the mouth, property is put down.GUIXIN, kidney, large intestine channel.Tranquilizing by nourishing the heart, loosening bowel to relieve constipation, hidroschesis.For deficiency of YIN-blood, fidgets due to deficiency is had a sleepless night, severe palpitation, dryness of the intestine constipation, night sweat due to yin deficiency.
Fructus Hordei Germinatus: sweet in the mouth, property is put down.Return spleen, stomach warp.Promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, galactopoiesis relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, distending pain of the breast, and women weans, hypochondriac pain due to stagnation of liverQI, stomachache due to hyperactive liver-QI attacking the stomach.
Beneficial effect of the present invention:
1. the present invention is according to the pathogeny of the heat stress of rabbit, carry out on the basis of a large amount of practical application, according to traditional medicine ancient prescription, form in conjunction with modern popular disease, nosetiology and immunologic theory screening, each crude drug synergism, comprehensive coordinate physiological metabolism, jointly play heat-clearing and toxic substances removing, diuretic quenched one's thirst, the effect of spleen benefiting and stimulating the appetite and raising body's immunity, improve appetite and the daily gain of rabbit, reduce mortality rate, solve the deficiency of single prescription, there is excellent anti-rabbit heat stress effect.
2. the present invention makes oral liquid, is easy to carry about with one and preserves, easy to use.
3. to have processing technology simple in the present invention, draws materials conveniently, cost is low, drug residue free and toxic and side effects, effective advantage, is a kind of green Chinese medicine preparation of anti-rabbit heat stress.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
embodiment 1
A kind of anti-rabbit heat stress oral liquid, is made up of the raw material of following weight portion: the Radix Astragali 30 parts, Flos Lonicerae 30 parts, crow select 18 parts, rule, Gypsum Fibrosum 30 parts, Rhizoma Coptidis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 20 parts, the Radix Rehmanniae, Semen Euryales 10 parts, Rhizoma Phragmitis 20 parts, Cortex Lycii 30 parts, Herba humuli scandentis 20 parts, Semen Platycladi 20 parts, 30 parts, Fructus Hordei Germinatus, HP-β-CD 30 parts, tea polyphenols 60 parts, sodium benzoate 0.2 part.(in embodiment, antiseptic directly says antiseptic or concrete title?)
A preparation method for anti-rabbit heat stress oral liquid, comprises the following steps:
1) each raw material is taken by weight;
2) Radix Astragali, Flos Lonicerae, Wu Diangui, Gypsum Fibrosum, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Semen Euryales, Rhizoma Phragmitis, Cortex Lycii, Herba humuli scandentis, Semen Platycladi and maltcrusher are pulverized, cross 60 mesh sieves, obtain raw material 1;
3) by HP-β-CD and raw material 1 mix homogeneously, add purified water by the weight ratio of 1:10, soak 1h, be heated to 50 DEG C, under 400W condition, multifunction supersonic extractor supersound extraction 0.5h, extracts 2 times, merge extractive liquid, filter, be evaporated to the weight of 5 times of raw materials 1, obtain filtrate;
4) tea polyphenols and sodium benzoate are added in filtrate, stir, 100 DEG C of steam sterilization 0.25h, fill, anti-rabbit heat stress oral liquid can be obtained.
Using method: use drinking water dilution rabbit heat stress oral liquid in 1:10-20 times of ratio under summer high temperature environment condition, allow rabbit freely drink, be used in conjunction 5-10 days.
embodiment 2
A kind of anti-rabbit heat stress oral liquid, it is characterized in that, be made up of the raw material of following weight portion: the Radix Astragali 20 parts, Flos Lonicerae 20 parts, crow select 10 parts, rule, Gypsum Fibrosum 20 parts, Rhizoma Coptidis 15 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, 10 parts, the Radix Rehmanniae, Semen Euryales 15 parts, Rhizoma Phragmitis 10 parts, Cortex Lycii 20 parts, Herba humuli scandentis 10 parts, Semen Platycladi 10 parts, 10 parts, Fructus Hordei Germinatus, methyl-B-cyclodextrin 10 parts, tea polyphenols 50 parts, Sodium Methyl Hydroxybenzoate 0.02 part.
A preparation method for anti-rabbit heat stress oral liquid, comprises the following steps:
1) each raw material is taken by weight;
2) Radix Astragali, Flos Lonicerae, Wu Diangui, Gypsum Fibrosum, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Semen Euryales, Rhizoma Phragmitis, Cortex Lycii, Herba humuli scandentis, Semen Platycladi and maltcrusher are pulverized, cross 70 mesh sieves, obtain raw material 1;
3) by methyl-B-cyclodextrin and raw material 1 mix homogeneously, add purified water by the weight ratio of 1:8, soak 0.5h, be heated to 60 DEG C, under 300W condition, multifunction supersonic extractor supersound extraction 0.25h, extracts 3 times, merge extractive liquid, filter, be evaporated to the weight of 5 times of raw materials 1, obtain filtrate;
4) tea polyphenols and Sodium Methyl Hydroxybenzoate are added in filtrate, stir, 100 DEG C of steam sterilization 0.25h, fill, anti-rabbit heat stress oral liquid can be obtained.
Using method is with embodiment 1.
embodiment 3
A kind of anti-rabbit heat stress oral liquid, it is characterized in that, be made up of the raw material of following weight portion: the Radix Astragali 50 parts, Flos Lonicerae 50 parts, crow select 25 parts, rule, Gypsum Fibrosum 50 parts, Rhizoma Coptidis 30 parts, the Rhizoma Atractylodis Macrocephalae 40 parts, 30 parts, the Radix Rehmanniae, Semen Euryales 5 parts, Rhizoma Phragmitis 30 parts, Cortex Lycii 50 parts, Herba humuli scandentis 30 parts, Semen Platycladi 30 parts, 40 parts, Fructus Hordei Germinatus, beta-schardinger dextrin-60 parts, tea polyphenols 70 parts, potassium sorbate 0.4 part.
A preparation method for anti-rabbit heat stress oral liquid, comprises the following steps:
1) each raw material is taken by weight;
2) Radix Astragali, Flos Lonicerae, Wu Diangui, Gypsum Fibrosum, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Semen Euryales, Rhizoma Phragmitis, Cortex Lycii, Herba humuli scandentis, Semen Platycladi and maltcrusher are pulverized, cross 60 mesh sieves, obtain raw material 1;
3) by beta-schardinger dextrin-and raw material 1 mix homogeneously, add purified water by the weight ratio of 1:20, soak 1h, be heated to 90 DEG C, under 500W condition, multifunction supersonic extractor supersound extraction 1h, extracts 2 times, merge extractive liquid, filter, be evaporated to the weight of 5 times of raw materials 1, obtain filtrate;
4) tea polyphenols and potassium sorbate are added in filtrate, stir, 100 DEG C of steam sterilization 0.25h, fill, anti-rabbit heat stress oral liquid can be obtained.
Using method is with embodiment 1.
embodiment 4
A kind of anti-rabbit heat stress oral liquid, it is characterized in that, be made up of the raw material of following weight portion: the Radix Astragali 40 parts, Flos Lonicerae 40 parts, crow select rule 10-25 part, Gypsum Fibrosum 40 parts, Rhizoma Coptidis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 20 parts, the Radix Rehmanniae, Semen Euryales 5-15 part, Rhizoma Phragmitis 20 parts, Cortex Lycii 20 parts, Herba humuli scandentis 10 parts, Semen Platycladi 10 parts, 20 parts, Fructus Hordei Germinatus, carboxymethyl-beta-cyclodextrin 50 parts, tea polyphenols 60 parts, sodium benzoate 0.1 part.
A preparation method for anti-rabbit heat stress oral liquid, comprises the following steps:
1) each raw material is taken by weight;
2) Radix Astragali, Flos Lonicerae, Wu Diangui, Gypsum Fibrosum, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Semen Euryales, Rhizoma Phragmitis, Cortex Lycii, Herba humuli scandentis, Semen Platycladi and maltcrusher are pulverized, cross 80 mesh sieves, obtain raw material 1;
3) by carboxymethyl-beta-cyclodextrin and raw material 1 mix homogeneously, add purified water by the weight ratio of 1:15, soak 1h, be heated to 80 DEG C, under 400W condition, multifunction supersonic extractor supersound extraction 1.5h, extracts 2 times, merge extractive liquid, filter, be evaporated to the weight of 5 times of raw materials 1, obtain filtrate;
4) tea polyphenols and sodium benzoate are added in filtrate, stir, 100 DEG C of steam sterilization 0.25h, fill, anti-rabbit heat stress oral liquid can be obtained.
Using method is with embodiment 1.
the effect test of anti-rabbit heat stress oral liquid in New Zealand rabbit is raised
1 materials and methods
1.1 EXPERIMENTAL DESIGN: select 180 health, body weight close (about 1.95kg)) New Zealand rabbit, be divided into 2 groups at random, i.e. test group and matched group, often organize 90, often group establishes 3 repetition, often repetition 30, male and female half and half.Analysis of variance, between group, original body mass difference is not remarkable.Test group uses the anti-rabbit heat stress oral liquid of gained of the present invention, in 1:12 times of ratio, with drinking water dilution, allows meat rabbit freely drink, is used in conjunction 7 days; Matched group uses drinking water, does not add any material, is used in conjunction 7 days.
1.2 experimental animals and feeding and management: before test, thoroughly clean rabbit home, cage tool, feed trough etc. and sterilize, and gives the anthelmintic of examination rabbit, vaccinate, numbered packets.Duration of test, under identical feeding environment condition, unification is raised in cages, and every 2d cleans 1 time, sterilizes 1 time weekly; Every day in morning 7:00, afternoon 14:00 and evening 20:00 measure rabbit home temperature, relative humidity, measure rabbit respiratory frequency and each 3 times of rectal temperature.Record the searching for food of rabbit, drink water, the situation such as healthy.Mean temperature 32.6 DEG C in duration of test rabbit home, average relative humidity 78.3%.
1.3 testing indexs: on-test and at the end of, to rabbit by only weighing, measure the situations such as record feed consumption rate, drinking-water, health every day, calculate feed intake, average daily gain, feed-weight ratio, survival rate, respiratory frequency and body temperature etc., result of the test as shown in Table 1 and Table 2.
2 result of the tests
Table 1 anti-rabbit heat stress oral liquid is on the impact of meat rabbit respiratory frequency and body temperature
| Group | Respiratory frequency (beat/min) | Body temperature (DEG C) |
| Matched group | 71 | 40.3 |
| Test group | 59 | 39.5 |
As the display of table 1 result of the test, in summer high temperature environment, matched group meat rabbit shows as accelerated breathing, and body temperature raises.By drinking the anti-rabbit heat stress oral liquid prepared by the present invention to meat rabbit, the realization of test group meat rabbit is respiratory frequency, temperature recovery is normal.
Table 2 anti-rabbit heat stress oral liquid is on the impact of rabbit fertility performance
| Group | Daily ingestion amount (g/d) | Average daily gain (g/d) | Feed-weight ratio | Survival rate (%) |
| Matched group | 75.9±2.9 | 22.4±1.7 | 3.39±0.50 | 87.7 |
| Test group | 80.3±3.2 | 24.9±2.1 | 3.22±0.39 | 100 |
As shown in table 2, by drinking the anti-rabbit heat stress oral liquid prepared by the present invention to meat rabbit, improve the appetite of New Zealand rabbit, daily gain and survival rate, test group improves 5.8% than matched group daily ingestion amount, average daily gain improves 11.2% respectively, and feed-weight ratio reduces 5.01%; Test group survival rate improves 12.3% than matched group respectively.
It should be noted last that, above embodiment is only in order to illustrate technical scheme of the present invention and unrestricted, although with reference to preferred embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that, can modify to technical scheme of the present invention or equivalent replacement, and not departing from the spirit and scope of technical solution of the present invention, it all should be encompassed in the middle of right of the present invention.
Claims (4)
1. an anti-rabbit heat stress oral liquid, it is characterized in that, be made up of the raw material of following weight portion: Radix Astragali 20-50 part, Flos Lonicerae 20-50 part, crow select rule 10-25 part, Gypsum Fibrosum 20-50 part, Rhizoma Coptidis 15-30 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Radix Rehmanniae 10-30 part, Semen Euryales 5-15 part, Rhizoma Phragmitis 10-30 part, Cortex Lycii 20-50 part, Herba humuli scandentis 10-30 part, Semen Platycladi 10-30 part, Fructus Hordei Germinatus 10-40 part, cyclodextrin 10-60 part, tea polyphenols 50-70 part, antiseptic 0.02-0.4 part.
2. anti-rabbit heat stress oral liquid according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: the Radix Astragali 30 parts, Flos Lonicerae 30 parts, crow select 18 parts, rule, Gypsum Fibrosum 30 parts, Rhizoma Coptidis 20 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, 20 parts, the Radix Rehmanniae, Semen Euryales 10 parts, Rhizoma Phragmitis 20 parts, Cortex Lycii 30 parts, Herba humuli scandentis 20 parts, Semen Platycladi 20 parts, 30 parts, Fructus Hordei Germinatus, cyclodextrin 30 parts, tea polyphenols 60 parts, antiseptic 0.2 part.
3. anti-rabbit heat stress oral liquid according to claim 1 and 2, is characterized in that, described cyclodextrin is the one in beta-schardinger dextrin-, methyl-B-cyclodextrin, carboxymethyl-beta-cyclodextrin, HP-β-CD.
4. a preparation method for the anti-rabbit heat stress oral liquid described in claim 1 or 2, is characterized in that, comprise the following steps:
1) each raw material is taken by weight;
2) Radix Astragali, Flos Lonicerae, Wu Diangui, Gypsum Fibrosum, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, the Radix Rehmanniae, Semen Euryales, Rhizoma Phragmitis, Cortex Lycii, Herba humuli scandentis, Semen Platycladi and maltcrusher are pulverized, cross 60-80 mesh sieve, obtain raw material 1;
3) by cyclodextrin and raw material 1 mix homogeneously, purified water is added by the weight ratio of 1:8-20, soak 0.5-1h, be heated to 50-90 DEG C, under 300-500W condition, multifunction supersonic extractor supersound extraction 0.25-1.5h, extract 2-3 time, merge extractive liquid, filter, be evaporated to the weight of 5 times of raw materials 1, obtain filtrate;
4) tea polyphenols and antiseptic are added in filtrate, stir, 100 DEG C of steam sterilization 0.25h, fill, anti-rabbit heat stress oral liquid of the present invention can be obtained.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805821A (en) * | 2012-08-21 | 2012-12-05 | 中国人民解放军第四一一医院 | Traditional Chinese medicine compound used for preventing heatstroke |
| CN103405713A (en) * | 2013-07-09 | 2013-11-27 | 刘华武 | Sanhuang powder for preventing and treating swine heat stress in summer |
| CN104187002A (en) * | 2014-09-14 | 2014-12-10 | 王桂红 | Chinese herbal medicine additive for preventing rabbit diseases |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805821A (en) * | 2012-08-21 | 2012-12-05 | 中国人民解放军第四一一医院 | Traditional Chinese medicine compound used for preventing heatstroke |
| CN103405713A (en) * | 2013-07-09 | 2013-11-27 | 刘华武 | Sanhuang powder for preventing and treating swine heat stress in summer |
| CN104187002A (en) * | 2014-09-14 | 2014-12-10 | 王桂红 | Chinese herbal medicine additive for preventing rabbit diseases |
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| 《粮食与饲料工业》 * |
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