CN105168959A

CN105168959A - Traditional Chinese medicine mixture for treating radioactive stomatitis

Info

Publication number: CN105168959A
Application number: CN201510615242.6A
Authority: CN
Inventors: 贾淑玉
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-09-17
Filing date: 2015-09-17
Publication date: 2015-12-23

Abstract

The invention discloses a traditional Chinese medicine mixture for treating radioactive stomatitis. According to traditional Chinese medicine, the symptoms that the mouth and throat are dry, the tong is red and coatings on the tongue are few are due to the fact that yin fluid is impaired and body fluid is consumed and harmed, heat and cancer toxin fight with each other, so that the heat and the cancer toxin is contained in each other, and therefore yin deficiency and heat toxin are the most common side reaction of radiotherapy. Therefore, the traditional Chinese medicine mixture is prepared from traditional Chinese medicine which is capable of nourishing yin, promoting the secretion of body fluid and clearing away heat and toxic materials, namely alstonia yunnanensis roots, ardisia mamillata hance, gentiana purdomii marq, drymoglossum piloselloides, ophiopogon roots, asparagus cochinchinensis, ludisia discolor herbs, commelina communis, nandina domestica leaves and golden cypress. Clinical tests prove that the total effective rate of the mixture is 97.14%, and the mixture is obviously superior to control groups.

Description

A kind of herb mixture for the treatment of radioactive stomatitis

Technical field

The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of herb mixture for the treatment of radioactive stomatitis.

Background technology

Radiotherapy is one of Main Means for the treatment of malignant tumor at present, and it is evident in efficacy, but in the treatment, tumor is controlled on the one hand; On the other hand, due to radiobiological effect, normal structure also correspondingly comes to harm, and often causes again the toxic and side effects of some whole bodies or local.Wherein Inflammation of Radioactive Oral Cavity is one of common complication, current Therapeutic Method is varied, but all cures slowly, weak curative effect, sometimes with side effect, some medicine also can stimulate the nervous system in affected part, and generation has an intense pain, for providing a kind of better Therapeutic Method to patient, we are according to pathogeny, suit the remedy to the case, develop one and have no side effect, prepare conveniently, herb mixture evident in efficacy.

Summary of the invention

The object of this invention is to provide a kind of herb mixture for the treatment of radioactive stomatitis.The traditional Chinese medical science is thought, the few tongue of dry mouth and throat, red tongue belongs to that cloudy liquid is impaired, the syndrome of body fluid being damaged, heat and cancer poison are fought mutually, and intoxicating heat is accumulate mutually, so the modal side reaction that is radiotherapy of the deficiency of YIN and pyretic toxicity, the local toxicity caused for radiotherapy, should be treated by YIN nourishing and the production of body fluid promoting, heat-clearing and toxic substances removing.

The object of the invention is to be achieved through the following technical solutions, the herb mixture of this treating radioactive stomatitis is made up of the Chinese medicine of following weight portion: Radix Alstoniae Yunnanensis 6-8 part, Herba Ardisiae Mamillatae 6-8 part, Herba Gentianae Algidae 6-8 part, Drymoglossum Herba Drymoglossi 6-8 part, Radix Ophiopogonis 7-9 part, Radix Asparagi 7-9 part, Herba Ludisiae Discoloris 7-9 part, Herba Dendrobii 9-11 part, Folium Mahoniae 9-11 part, Cortex Phellodendri 9-11 part.

Preferred: Radix Alstoniae Yunnanensis 7 parts, Herba Ardisiae Mamillatae 7 parts, Herba Gentianae Algidae 7 parts, Drymoglossum Herba Drymoglossi 7 parts, Radix Ophiopogonis 8 parts, Radix Asparagi 8 parts, Herba Ludisiae Discoloris 8 parts, Herba Dendrobii 10 parts, Folium Mahoniae 10 parts, Cortex Phellodendri 10 parts.

Preparation method: above-mentioned Chinese medicine is traditionally made decoction.

Fang Zhong: Radix Alstoniae Yunnanensis heat-clearing and toxic substances removing, control stomatitis; Herba Ardisiae Mamillatae clearing away heat-damp and promoting diuresis, to invigorate blood circulation and the stasis of blood; Herba Gentianae Algidae eliminating pathogen in the liver gallbladder excess-fire, clearing away damp-heat, antitussive, stomach invigorating; Drymoglossum Herba Drymoglossi clearing away heat-damp and promoting diuresis, removing toxic substances parasite killing; Radix Ophiopogonis nourishing YIN and moistening the lung, the relieving restlessness that clears away heart-fire, reinforcing stomach reg fluid; Radix Asparagi is nourshing Yin and drynsessmoistening prescription, lung heat clearing pathogenic fire reducing; Herba Ludisiae Discoloris nourishing YIN and moistening the lung, clearing away heat and cooling blood; Herba Dendrobii replenishing YIN and removing heat, strengthening the spleen and stomach, control consumption of YIN caused by febrile disease; Folium Mahoniae heat clearing away tonify deficiency, relieving cough and resolving phlegm; Cortex Phellodendri heat clearing away, dampness, pathogenic fire purging, removing toxic substances.

Clinical data

1. physical data accepts in July, 2010 ~ 2012 Inflammation of Radioactive Oral Cavity patient 70 example in year April for medical treatment, wherein man 40 example, female 30 example; Age 18-66 year, average 45 years old; Be tumor of head and neck and accept radiotherapy patient, and have radioactivity oral cavity reaction in various degree.By random packet, be divided into treatment group 35 example (Chinese medicine plus radiotherapy), matched group 35 example (the safe collutory plus radiotherapy of mouth).

2. Therapeutic Method treatment group adopts new herb mixture: take Radix Alstoniae Yunnanensis 7 grams, Herba Ardisiae Mamillatae 7 grams, Herba Gentianae Algidae 7 grams, Drymoglossum Herba Drymoglossi 7 grams, Radix Ophiopogonis 8 grams, Radix Asparagi 8 grams, Herba Ludisiae Discoloris 8 grams, Herba Dendrobii 10 grams, Folium Mahoniae 10 grams, Cortex Phellodendri 10 grams, traditionally make decoction, dividing and sooner or later take for twice, 7 days is a course for the treatment of; The matched group safe collutory of mouth, every day gargles for 3 times, within 7 days, is a course for the treatment of.

3. the reaction of observation index oral cavity is divided into I mono-III degree.I degree: only have xerostomia, can enter xerophagia; II degree: xerostomia is heavier, pharyngalgia, but without oral ulcer, enter xerophagia more difficult, can soft diet be entered; III degree: serious xerostomia, has oral ulcer, can only influent stream matter.

4, efficacy determination: healing of canker sores heals, xerostomia symptom is improved; Improvement xerostomia pharyngalgia symptom is improved, and alleviates I degree; Invalid symptom is without improvement, or oral ulcer no healing.

5, therapeutic outcome

Treatment group and the therapeutic outcome after treatment of control group two course for the treatment of as follows:

Group row	N (example)	Cure	Take a turn for the better	Invalid	Total effective rate
						Treatment group	35	25	9	1	97.14％
Matched group	35	18	8	9	74.28％

Through statistical test, two groups of comparitive study have significant difference P < 0.01, and treatment group is better than matched group.

Detailed description of the invention

Embodiment one: take Radix Alstoniae Yunnanensis 6 grams, Herba Ardisiae Mamillatae 6 grams, Herba Gentianae Algidae 6 grams, Drymoglossum Herba Drymoglossi 6 grams, Radix Ophiopogonis 7 grams, Radix Asparagi 7 grams, Herba Ludisiae Discoloris 7 grams, Herba Dendrobii 9 grams, Folium Mahoniae 9 grams, Cortex Phellodendri 9 grams, traditionally make decoction, dividing and sooner or later take for twice, 7 days is a course for the treatment of.

Embodiment two: take Radix Alstoniae Yunnanensis 7 grams, Herba Ardisiae Mamillatae 7 grams, Herba Gentianae Algidae 7 grams, Drymoglossum Herba Drymoglossi 7 grams, Radix Ophiopogonis 8 grams, Radix Asparagi 8 grams, Herba Ludisiae Discoloris 8 grams, Herba Dendrobii 10 grams, Folium Mahoniae 10 grams, Cortex Phellodendri 10 grams, traditionally make decoction, dividing and sooner or later take for twice, 7 days is a course for the treatment of.

Embodiment three: Radix Alstoniae Yunnanensis 8 parts, Herba Ardisiae Mamillatae 8 parts, Herba Gentianae Algidae 8 parts, Drymoglossum Herba Drymoglossi 8 parts, Radix Ophiopogonis 9 parts, Radix Asparagi 9 parts, Herba Ludisiae Discoloris 9 parts, Herba Dendrobii 11 parts, Folium Mahoniae 11 parts, Cortex Phellodendri 11 parts.

Claims

1. a herb mixture for treating radioactive stomatitis, is characterized in that this herb mixture is made up of the Chinese medicine of following weight portion: Radix Alstoniae Yunnanensis 6-8 part, Herba Ardisiae Mamillatae 6-8 part, Herba Gentianae Algidae 6-8 part, Drymoglossum Herba Drymoglossi 6-8 part, Radix Ophiopogonis 7-9 part, Radix Asparagi 7-9 part, Herba Ludisiae Discoloris 7-9 part, Herba Dendrobii 9-11 part, Folium Mahoniae 9-11 part, Cortex Phellodendri 9-11 part.

2. the herb mixture of a kind for the treatment of radioactive stomatitis as claimed in claim 1, is characterized in that this herb mixture is made up of the Chinese medicine of following weight portion: preferred: Radix Alstoniae Yunnanensis 7 parts, Herba Ardisiae Mamillatae 7 parts, Herba Gentianae Algidae 7 parts, Drymoglossum Herba Drymoglossi 7 parts, Radix Ophiopogonis 8 parts, Radix Asparagi 8 parts, Herba Ludisiae Discoloris 8 parts, Herba Dendrobii 10 parts, Folium Mahoniae 10 parts, Cortex Phellodendri 10 parts.