CN105168910A - Traditional Chinese medicinal preparation for treating ankylosing spondyloarthritis and preparation method of traditional Chinese medicinal preparation - Google Patents

Traditional Chinese medicinal preparation for treating ankylosing spondyloarthritis and preparation method of traditional Chinese medicinal preparation Download PDF

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CN105168910A
CN105168910A CN201510563744.9A CN201510563744A CN105168910A CN 105168910 A CN105168910 A CN 105168910A CN 201510563744 A CN201510563744 A CN 201510563744A CN 105168910 A CN105168910 A CN 105168910A
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王玉海
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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating ankylosing spondyloarthritis and a preparation method of the traditional Chinese medicinal preparation, belonging to the field of traditional Chinese medicine. The active ingredients of the traditional Chinese medicinal preparation consist of the following raw materials: wendlandia uvariifolia, Chinese arundina herb, solanum torvum, pothos chinensis, luffa stem, field horsetail, ficus formosana, entada phaseoloides, beefwood-like clubmoss herb, effuse baliospermum roots and leaves, honeycomb, bidens bipinnata, heynea trijuga, birch bark, commen bomhax flower and luisia morsei. The traditional Chinese medicinal preparation disclosed by the invention, since the selected medicinal materials are appropriately matched in accordance with the theories of traditional Chinese medicine and modern medicine, has functions of dispelling cold and removing dampness, promoting blood circulation and removing stasis, and activating meridians to stop pain, and has a unique curative effect on ankylosing spondyloarthritis and the like; and the traditional Chinese medicinal preparation is significant in curative effect, relatively low in cost, free from reoccurrence after curing, safe and reliable and free from any toxic or side effect, and the traditional Chinese medicinal preparation is capable of achieving a purpose of treating both symptoms and root causes.

Description

One treats the arthritic Chinese medicine preparation of rigid spine and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to one and treat the arthritic Chinese medicine preparation of rigid spine and preparation method.
Background technology
The disease that ankylosing spondylitis (AS) is is cardinal symptom with sacroiliac joint and spinal column attachment point inflammation.With HLA-B27 in associating by force.Certain micro-organisms (as klebsiella bacillus) and susceptible person autologous tissue have common antigen, can exception throw immunne response.The large joints of extremity, and annulus fibrosus disci intervertebralis and neighbouring connective fiberization thereof and ossified, and ankylosis is the chronic inflammatory disease of lesion characteristic.Ankylosing spondylitis belongs to rheumatism category, is the one of seronegative spondyloanthropathy.This cause of disease is still not clear, and is take spinal column as the chronic disease at major lesions position, involves sacroiliac joint, cause rigid spine and fibrosis, cause eye, lung, muscle, skeleton pathological changes in various degree, belong to autoimmune disease.
Patient AS has arthropathy more, and first the overwhelming majority invades sacroiliac joint, is uply developed to cervical vertebra later.A few patients is first invaded by cervical vertebra or several spinal column segment simultaneously, and also can invade periarticular, there is inflammatory pain in joint, early lesion place, and with periarticular muscles spasm, have stiff sense, morning rises obviously.Also pain at night can be shown as, through movable or take analgesic and alleviate.Along with PD, arthralgia alleviates, and each spinal column segment and joint motion limited and lopsided, late period whole spinal column and lower limb become stiff arc, to pre-buckling.
(1) sacroiliitis: about patient 90%AS shows as sacroiliitis at first.Later uply be developed to cervical vertebra, show as the lumbago of recurrent exerbation, lumbosacral region stiff sense, alternately there is lumbago and both sides pain of buttock in intermittent or both sides, can be radiated to thigh, no positive sign, SLR negative.But directly pressing or stretching, extension sacroiliac joint can cause pain.Some patient is without sacroiliitis symptom, and only x-ray inspection finds that there is abnormal change.About 3%AS cervical vertebra is got involved the earliest, and later downward progression is to lumbosacral region, and the 7%AS almost full section of spinal column gets involved simultaneously.
(2) lumbal vertebra: lumbar vertebra is subject to for a long time, and majority shows as lower back portion and waist limitation of activity.Waist is anteflexion, dorsiflexion, lateral bending and rotation all can be limited.Health check-up can find that lumbar vertebra ridge is dashed forward tenderness, the other muscle spasm of lumbar vertebra; Can there be psoas muscle atrophy in later stage.
(3) thoracic vertebra pathological changes: thoracic vertebra, by for a long time, shows as backache, shirtfront and pleurobranch pain, the most common is bow-backed deformity.As costovertebral joints, presternum body joint, sternoclavicular joint and articulationes interchondrales are subject to for a long time, then in band shape chest pain, thoracic expansion is limited, and when air-breathing cough or sneeze, chest pain increases the weight of.Severe patient thorax remains on expiration state, and thoracic expansion calibration ordinary person reduces by more than 50%, and ventral breathing therefore can only be leaned on to assist.Because splanchnocoel capacity reduces, cause cardio-pulmonary function and digestive functional disturbance.
(4) cervical spondylosis: first a few patients shows as cervical spondylitis, first has ceruical uertebra part pain, radiates along cervical region to head arm.Spasm when musculi colli starts, later atrophy, lesion growth can be developed to neck thoracic kyphosis deformity.Head movement is obviously limited, is often fixed on anteflexion position, can not face upward, lateral bending or rotation.Severe patient only can see the fritter ground in oneself toe front, can not come back and look squarely.
(5) periarticular pathological changes: about half patient AS has of short duration acute peripheral arthritis, about 25% has permanent periarticular to damage.Generally multiple high point of being born in is saved, and lower limb are more than upper limb.Shoulder joint is by for a long time, and joint motion is limited, and pain is more obvious, and the activity such as to comb one's hair, raise one's hand is all limited.During infringement knee joint, then joint is compensating curvature, makes the daily life such as walking, sitting more difficult.Few infringement elbow, wrist and foot joint.
In addition, pubic symphysis also can be got involved, and pelvis upper limb, ischial tuberosity, femoral greater trochanter and heel portion can have osteitis symptom, and Early manifestation is that local soft tissue swells, bitterly, has late period bone thick.Before general periarticular inflammation can occur in spondylitis or after, local symptom and rheumatoid arthritis are not easily distinguished, but it is less to leave over lopsided person.
The arthritic western medical treatment less effective of current treatment rigid spine, mostly be oral endo-medicine, long-term taking side effect is larger, the conventional treatment such as immunosuppressant and non-thalline antibiotic medicine clinically, onset symptoms is changeable, lacks specificity, the very easily delay treatment by mistaken diagnosis, severe one can cause human body lopsided and disabled, has become the disease of serious harm human body health.
Summary of the invention
The invention provides one and treat the arthritic Chinese medicine preparation of rigid spine and preparation method; Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of dispelling cold and removing dampness, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, to treatment rigid spine arthritis etc., there is unique curative effect, and evident in efficacy, cost is lower, non-relapse after healing, safe and reliable, without any side effects, the object for the treatment of both the principal and secondary aspects of a disease can be arrived.
For achieving the above object, technical scheme of the present invention is implemented as follows:
One treats the arthritic Chinese medicine preparation of rigid spine, and raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the arthritic Chinese medicine preparation of rigid spine, comprise following processing step:
(1) Radix seu Folium Wendlandiae Uvariifoliae, Herba Arundinae Chinensis, Radix Solani Torvi, Herba Pothi Chinensis, Herba Equiseti Arvinsis, Taiwan banyan and Radix Merremiae hungaiensis are cleaned, put into
In container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Ramulus Luffae charred medicinal herb with its property retained is ground into powder, cross 180 orders, obtain fine powder, for subsequent use;
(3) Nidus Vespae, Cortex Betulae Luminiferae and silk cotton are put into container, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(Caulis Endadae phaseoloidis, Lycopodium casuarinoides Spring and Radix heyneae trijugae are cleaned by 4), immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 4 times amount, heating extraction 3 hours, reclaim ethanol, and filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(5) Herba Bidentis Bipinnatae and Radix Seu Herba Luisiae Morsei are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the arthritic Chinese medicine preparation for the treatment of rigid spine of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Radix seu Folium Wendlandiae Uvariifoliae: acrid in the mouth, cool in nature; Return Liver Channel.Expelling wind and removing dampness, dissipating blood stasis for subsidence of swelling, hemostasia and promoting granulation.For rheumatic arthritis, traumatic injury.Traumatic hemorrhage is controlled in external, and skin infection festers and do not close up for a long time.
Herba Arundinae Chinensis: bitter in the mouth, property is put down.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Cure mainly pyretic stranguria, jaundice, edema, beriberi edema, hernia is suffered from abdominal pain, rheumatic arthralgia, venom, sore and toxic, traumatic injury." choosing of Simao, Yunnan Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, wind-damp dispelling, antiinflammatory, diuresis.Treating rheumatic lumbago and skelalgia, stomachache, urinary tract infection, beriberi edema, alimentary toxicosis." decoct soup
Radix Solani Torvi: acrid in the mouth, slightly cool in nature, slightly poisonous.Dissipating blood stasis, stimulates the menstrual flow, detumescence, pain relieving, cough-relieving.For traumatic injury stasis of blood pain, lumbar muscle strain, stomachache, toothache, amenorrhea, chronic cough." register planted by Guangxi medicine ": " loose blood, pain relieving.Control hemoptysis, toothache, innominate toxic swelling." decoct soup
Herba Pothi Chinensis: lightly seasoned, property is put down.Expelling wind and removing dampness, promoting blood circulation to remove blood stasis, removing food stagnancy, cough-relieving.For traumatic injury, advanced schistosomiasis hepatosplenomegaly, rheumatic arthritis, infantile malnutrition, cough, fracture is controlled in external, otitis media, sinusitis." Guangxi Chinese medicinal herbal " carries: " heat clearing away, removing toxic substances, wind-damp dispelling.Dispelling the wind and dampness pathogens osteodynia, inflammation of external auditory meatus." decoct soup
Ramulus Luffae: bitter in the mouth, cold nature; GUIXIN, spleen, kidney channel.Dredge the meridian passage, relieving cough and resolving phlegm.Lumbago, cough, rhinitis, bronchitis." book on Chinese herbal medicine asks former " carries: " and blood vessels, words grain, grows water, only pain over the perineum, invigorating middle warmer spleen invigorating, consumer edema.Control blood depletion few, waist knee joint numb limbs and tense tendons, puerperal infantile convulsion, regulating menstruation.”
Herba Equiseti Arvinsis: bitter in the mouth, cool in nature, nontoxic; Return lung, stomach, Liver Channel.Heat clearing away, removing heat from blood, cough-relieving, diuresis.Control haematemesis, epistaxis, have blood in stool, vicarious menstruation, cough and asthma, gonorrhea." Shaanxi Chinese herbal medicine " carries: " clearing away heat and promoting diuresis, hemostasis, detumescence.Control urinary tract infection, difficulty and pain in micturition, fracture, epistaxis, spitting of blood, enterorrhagia, menorrhagia.”
Taiwan banyan: sweet in the mouth, micro-puckery, property is put down.Easing the affected liver and spleen, clearing away heat-damp and promoting diuresis.Cure mainly acute hepatitis, chronic hepatitis, spinal column is sprained, acute nephritis, urinary system infection.
Caulis Endadae phaseoloidis: bitter in the mouth, puckery, property is put down, poisonous; Return kidney channel.Expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral.Main air pain of dampness syndrome, traumatic injury, lumbar muscle strain, numb limbs and tense tendons." register planted by Guangxi medicine " carries: " stimulate the menstrual flow, the skin ulcer that disappears swells, dispelling the wind and dampness pathogens lumbago.”
Lycopodium casuarinoides Spring: taste is micro-sweet, warm in nature, nontoxic; Return liver, kidney channel.Expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation, improving eyesight is detoxified.Cure mainly rheumatic arthritis, traumatic injury, bones and muscles pain, menoxenia, tetany, nyctalopia, night sweat, lumbago due to pathogenic wind-dampness, lumbar muscle strain, burn due to hot liquid or fire, sore swollen toxin." the practical Chinese herbal medicine in Guangxi newly selects " carries: " relaxing muscles and tendons and activating QI and blood in the collateral, antiinflammatory dehumidifies.Cure mainly nyctalopia, night sweat, lumbago due to pathogenic wind-dampness, infantile fever caused by exogenous pathogens.”
Radix Merremiae hungaiensis: acrid in the mouth, slightly warm in nature; Return liver, gallbladder, large intestine channel.Removing toxic substances anthelmintic, synthetism, dissipating blood stasis for subsidence of swelling.Control traumatic injury, fracture, ascariasis, icterohepatitis.
Nidus Vespae: sweet in the mouth, property is put down, and returns stomach warp.Dispel the wind counteracting toxic substances, parasite killing pain relieving, antiallergic." choosing of Simao, Yunnan Chinese herbal medicine " carries: " relaxing muscles and tendons and activating QI and blood in the collateral, method rheumatism, diuresis.Cure mainly rheumatic arthritis, waist knee joint arthralgia chiefly caused by damp pathogen, oedema due to nephritis." modern medicine study confirmation, Nidus Vespae preparation has the effect promoting Immune Function.
Herba Bidentis Bipinnatae: bitter, be slightly cold; Return lung, spleen, stomach, large intestine channel.Heat-clearing and toxic substances removing, clearing away heat to cure dysentery, promoting blood circulation and stopping pain, for cold, fever, pharyngalgia, acute appendicitis, jaundice, malaria, venom, prurigo, traumatic injury, lumbago, arthralgia, stomachache, dysphagic, for diarrhoea, dysentery etc.Modern medicine study confirms, Herba Bidentis Bipinnatae has replenishing QI to invigorate the spleen effect concurrently, can be used for body nihility power, diarrhea due to hypofunction of the spleen.
Radix heyneae trijugae: bitter in the mouth, cool in nature, slightly poisonous.Heat-clearing and toxic substances removing, wind-damp dispelling, throat.Cure mainly lumbago, skelalgia of rheumatism, pharyngolaryngitis, tonsillitis, heart peratodynia.
Cortex Betulae Luminiferae: bitter in the mouth, property is put down.Clearing away heat-damp and promoting diuresis, removing toxic substances.For acute tonsillitis, bronchitis, pneumonia, enteritis, dysentery, hepatitis, oliguria yellow skin, acute mastitis; Burn and scald is controlled in external, carbuncle furuncle and phyma poison.
Silk cotton: acrid in the mouth, sweet, property is put down; Enter stomach, large intestine channel.Clearing away heat-damp and promoting diuresis, promoting blood circulation and detumescence.Cure mainly chronic gastritis, gastric ulcer, have loose bowels, dysentery, waist foot is unsuccessful, and lower limb knee joint pain, skin ulcer are swollen, traumatic injury etc.Modern medicine study confirms, silk cotton has clearing away heat and cooling blood, removes stagnant removing food stagnancy, regulates human immunity and anticancer function.
Radix Seu Herba Luisiae Morsei: bitter in the mouth, pungent, cool in nature, mild toxicity; Return lung, the heart, liver, kidney channel.Heat-clearing and toxic substances removing, expelling wind and removing dampness.Main malaria, carbuncle, laryngopharynx swelling and pain, rheumatic arthralgia, edema, nebulousurine, leukorrhagia, traumatic injury, medicine or alimentary toxicosis." practical Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, removing heat from blood is subsided a swelling.Control hypertension, rheumatalgia, wind syndrome of head.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of dispelling cold and removing dampness, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, to treatment rigid spine arthritis etc., there is unique curative effect, and evident in efficacy, cost is lower, non-relapse after healing, safe and reliable, without any side effects, the object for the treatment of both the principal and secondary aspects of a disease can be arrived.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Treat a preparation method for the arthritic Chinese medicine preparation of rigid spine, comprise following processing step:
(1) Radix seu Folium Wendlandiae Uvariifoliae, Herba Arundinae Chinensis, Radix Solani Torvi, Herba Pothi Chinensis, Herba Equiseti Arvinsis, Taiwan banyan and Radix Merremiae hungaiensis are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Ramulus Luffae charred medicinal herb with its property retained is ground into powder, cross 180 orders, obtain fine powder, for subsequent use;
(3) Nidus Vespae, Cortex Betulae Luminiferae and silk cotton are put into container, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(Caulis Endadae phaseoloidis, Lycopodium casuarinoides Spring and Radix heyneae trijugae are cleaned by 4), immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 4 times amount, heating extraction 3 hours, reclaim ethanol, and filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(5) Herba Bidentis Bipinnatae and Radix Seu Herba Luisiae Morsei are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the arthritic Chinese medicine preparation for the treatment of rigid spine of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 1 (every 0.5g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the arthritic Chinese medicine preparation for the treatment of rigid spine, select the routine clinical observation of rigid spine arthritic 180 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 90 example, wherein male 45 example, women 45 example, 20 ~ 61 years old age, 40.5 years old mean age, average course of disease 3 years; Matched group 180 example, wherein male 45 example, women 45 example, 21 ~ 60 years old age, 40.5 years old mean age, average course of disease 3 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 1 (every 0.5g), warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes ibuprofen modified release capsule, oral, adult, one time 1,2 times on the one (sooner or later each once), the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: above-mentioned symptom all disappears, functional activity recovers normal, and physical recovery is normal.
(2) effective: above-mentioned symptom obviously improves, functional activity is clearly better, and health takes a turn for the better to some extent.
(3) effective: above-mentioned symptom makes moderate progress, and functional activity takes a turn for the better to some extent, and health is clearly better.
(4) invalid: by treating rear above-mentioned symptom without improving or increasing the weight of.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 43 examples, effective 29 examples, effective 15 examples, invalid 3 examples, cure rate 47.8%, total effective rate 96.7%.
29 examples are cured, effective 25 examples, effective 17 examples, invalid 19 examples, cure rate 32.2%, total effective rate 78.9% in matched group.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Zhang, female, 27 years old, people from Wuhu.Patient's neck pain in the lumbar region pain is stiff, and functional activity is limited, the convex deformity of waist breast section, spinous process percussion pain, and jaw breast, apart from 9cm, refers to distance 39cm, looks into X sheet and show: cervical vertebra fiber is stiff, and all joints of lumbar vertebra are that Bamboo-shaped changes, and sacroiliac joint is fuzzy.Limbs are tired heavy, obtain hot, subtract, and meet cold increasing the weight of, pale tongue, white, slippery and moist fur, stringy and rolling pulse.Be diagnosed as " ankylosing spondylitis ".Take Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, be clearly better, lumbago obviously alleviates, and after continuing to take 1 course for the treatment of, symptom all disappears, and movable recovery is normal.
2, poplar, man, 30 years old, people from Quzhou, Zhejiang.Patient suffers from ankylosing spondylitis for many years, and once oral sulfasalazine and that effect of diclofenac are general, patient's waist is anteflexion, after stretch and lateral bending function all limited, cervical vertebra leans forward, function limitation, with obvious feeling of fatigue, sleep poor, soreness of the waist and knees, fear of cold, trick is sent out cool, gives Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, symptom takes a turn for the better to some extent, after continuing to take 2 courses for the treatment of, transference cure, physical recovery is normal.
3, certain is revived, female, 29 years old, Heyuan people.Patient's waist is stiff for morning, tired heavy, and meet cold increasing the weight of, obtain warm alleviating, difficulty of squatting down, waist functional activity is limited, and look into X sheet and show: double hip joint is fuzzy, right hip joint space narrows, and lumbar vertebra is that ring sample becomes.Light red tongue, moist and slippery fur, stringy pulse.Be diagnosed as " ankylosing spondylitis ".Take Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, lumbago obviously alleviates, and movable function and tcm symptom sign improve, and after continuing to take 1 course for the treatment of, symptom disappears substantially, and functional activity improves obviously, first works.
4, Lu, man, 33 years old, Qujing of Yunnan people.Patient squats down difficulty, and neck waist and two hip pain, morning are stiff, stretches and lateroflexion rotates all limited, width of chest mobility 2.5cm after cervical vertebra, stretch after lumbar vertebra and lateroflexion limited, refer to distance 34cm, look into X sheet and show: double hip joint narrow gaps is fuzzy, and small joints in lumbar spine is fuzzy.Be diagnosed as " ankylosing spondylitis ".After taking 1 course for the treatment of, lumbago obviously alleviates, and movable function and tcm symptom sign improve, and after taking 2 courses for the treatment of, lower back functional activity recovers normal.
5, Peng, female, 41 years old, people from Yibin, Sichuan.Patient's waist and sacrum pain 3 years, companion's deadlock in morning sense half a year, fear of cold is serious, soreness of the waist and knees, overcast and rainyly increases the weight of, and night stands up difficulty, sleeps poor, receive can, time have abdominal distention, large loose stool, pale tongue with white fur, slow pulse.Remove hospital admission, be diagnosed as ankylosing spondylitis, once the medicine such as oral sulfasalazine, poor effect, gives Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, warm very comfortable in individual back, conscious abdominal part is also loose much, after taking 3 curative effects, lumbus sacrum pain disappears, and follows up a case by regular visits to and does not recur so far.
6, certain is appointed, man, 47 years old, people from Yichang.Patient's right hip knee joint pain, stiff, right shoulder and the tired heavy stiff pain of lumbosacral region, obtain Wen Ze and subtract, meet cold increasing the weight of, walk lamely, look into X sheet and show: bilateral sacroiliac joint gap turn narrow, small joints in lumbar spine is fuzzy.Be diagnosed as " ankylosing spondylitis ".Take Chinese medicine preparation of the present invention treatment, after taking 1 course for the treatment of, lower back functional activity makes moderate progress, and after continuing to take 2 courses for the treatment of, lower back functional activity is normal, follows up a case by regular visits to without recurrence after 1 year.

Claims (5)

1. treat the arthritic Chinese medicine preparation of rigid spine, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
44 ~ 71 parts, Radix seu Folium Wendlandiae Uvariifoliae 57 ~ 80 parts of Herba Arundinae Chinensiss 49 ~ 78 parts of Radix Solani Torvi 48 ~ 74 parts of Herba Pothi Chinensis
Ramulus Luffae 44 ~ 70 portions of Herba Equiseti Arvinsiss 41 ~ 69 parts of Taiwan banyan 40 ~ 69 Fen Caulis Endadae phaseoloidis 38 ~ 65 parts
Lycopodium casuarinoides Spring 33 ~ 61 parts of Radix Merremiae hungaiensis 31 ~ 59 parts of Nidus Vespae 28 ~ 58 portions of Herba Bidentis Bipinnatae 25 ~ 53 parts
Radix heyneae trijugae 23 ~ 49 parts of Cortex Betulae Luminiferaes 19 ~ 45 parts of silk cotton 17 ~ 38 parts of Radix Seu Herba Luisiae Morseis 14 ~ 33 parts.
2. one according to claim 1 treats the arthritic Chinese medicine preparation of rigid spine, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
49 ~ 68 parts, Radix seu Folium Wendlandiae Uvariifoliae 61 ~ 77 parts of Herba Arundinae Chinensiss 53 ~ 73 parts of Radix Solani Torvi 52 ~ 70 parts of Herba Pothi Chinensis
Ramulus Luffae 48 ~ 66 portions of Herba Equiseti Arvinsiss 45 ~ 64 parts of Taiwan banyan 44 ~ 64 Fen Caulis Endadae phaseoloidis 42 ~ 60 parts
Lycopodium casuarinoides Spring 38 ~ 57 parts of Radix Merremiae hungaiensis 35 ~ 54 parts of Nidus Vespae 33 ~ 53 portions of Herba Bidentis Bipinnatae 30 ~ 48 parts
Radix heyneae trijugae 27 ~ 45 parts of Cortex Betulae Luminiferaes 23 ~ 41 parts of silk cotton 21 ~ 34 parts of Radix Seu Herba Luisiae Morseis 18 ~ 30 parts.
3. one according to claim 1 treats the arthritic Chinese medicine preparation of rigid spine, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
53 ~ 62 parts, Radix seu Folium Wendlandiae Uvariifoliae 66 ~ 74 parts of Herba Arundinae Chinensiss 58 ~ 68 parts of Radix Solani Torvi 57 ~ 65 parts of Herba Pothi Chinensis
Ramulus Luffae 53 ~ 61 portions of Herba Equiseti Arvinsiss 50 ~ 59 parts of Taiwan banyan 49 ~ 57 Fen Caulis Endadae phaseoloidis 47 ~ 55 parts
Lycopodium casuarinoides Spring 43 ~ 51 parts of Radix Merremiae hungaiensis 39 ~ 50 parts of Nidus Vespae 38 ~ 48 portions of Herba Bidentis Bipinnatae 35 ~ 43 parts
Radix heyneae trijugae 32 ~ 40 parts of Cortex Betulae Luminiferaes 28 ~ 36 parts of silk cotton 25 ~ 28 parts of Radix Seu Herba Luisiae Morseis 22 ~ 26 parts.
4. one according to claim 1 treats the arthritic Chinese medicine preparation of rigid spine, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
58 parts, Radix seu Folium Wendlandiae Uvariifoliae 70 parts of Herba Arundinae Chinensiss 63 parts of Radix Solani Torvi 61 parts of Herba Pothi Chinensis
Ramulus Luffae 57 portions of Herba Equiseti Arvinsiss 54 parts of Taiwan banyan 53 Fen Caulis Endadae phaseoloidis 50 parts
Lycopodium casuarinoides Spring 47 parts of Radix Merremiae hungaiensis 45 parts of Nidus Vespae 43 portions of Herba Bidentis Bipinnatae 39 parts
Radix heyneae trijugae 36 parts of Cortex Betulae Luminiferaes 32 parts of silk cotton 27 parts of Radix Seu Herba Luisiae Morseis 24 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the arthritic Chinese medicine preparation of rigid spine, it is characterized in that: comprise following processing step:
(1) Radix seu Folium Wendlandiae Uvariifoliae, Herba Arundinae Chinensis, Radix Solani Torvi, Herba Pothi Chinensis, Herba Equiseti Arvinsis, Taiwan banyan and Radix Merremiae hungaiensis are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Ramulus Luffae charred medicinal herb with its property retained is ground into powder, cross 180 orders, obtain fine powder, for subsequent use;
(3) Nidus Vespae, Cortex Betulae Luminiferae and silk cotton are put into container, carry out pulverization process, grind into powder, cross 160 order fine powders, for subsequent use;
(Caulis Endadae phaseoloidis, Lycopodium casuarinoides Spring and Radix heyneae trijugae are cleaned by 4), immerse the alcohol solution dipping 1 ~ 2 hour of 70% of 4 times amount, heating extraction 3 hours, reclaim ethanol, and filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(5) Herba Bidentis Bipinnatae and Radix Seu Herba Luisiae Morsei are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(6) by thick paste, fine powder and the juice mixing obtained by above-mentioned steps (1) ~ (5), make capsule, obtain the described arthritic Chinese medicine preparation for the treatment of rigid spine.
CN201510563744.9A 2015-09-07 2015-09-07 Traditional Chinese medicinal preparation for treating ankylosing spondyloarthritis and preparation method of traditional Chinese medicinal preparation Pending CN105168910A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1259369A (en) * 1999-10-14 2000-07-12 周沛 Medicine for treating rigid spine inflammation and prepn. method thereof
CN101040927A (en) * 2007-04-19 2007-09-26 于振鹏 Chinese traditional medicine compound took orally for treating ankylosing spondylitis
CN104069447A (en) * 2014-07-24 2014-10-01 张晓丽 Traditional Chinese medicine preparation for treating ankylosing spondylitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1259369A (en) * 1999-10-14 2000-07-12 周沛 Medicine for treating rigid spine inflammation and prepn. method thereof
CN101040927A (en) * 2007-04-19 2007-09-26 于振鹏 Chinese traditional medicine compound took orally for treating ankylosing spondylitis
CN104069447A (en) * 2014-07-24 2014-10-01 张晓丽 Traditional Chinese medicine preparation for treating ankylosing spondylitis

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