CN105168617A - Traditional Chinese medicine composition for treating qi-blood deficiency type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of hemorrhoidal disease - Google Patents

Abstract

The invention belongs to the technical field of medicines, and particularly relates to traditional Chinese medicine composition for treating qi-blood deficiency type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of a hemorrhoidal disease. The traditional Chinese medicine composition comprises traditional Chinese medicines in parts by weight as follows: 4-8 parts of annular holostemma, 4-8 parts of Chinese incarvilla herb of Tibet, 4-8 parts of rex woodbetony, 4-8 parts of roots of false-yellowflower milkwort, 4-8 parts of ficus esquiroliana, 4-8 parts of roots of bilobed grewia, 4-8 parts of mulberry fruits, 4-8 parts of linseed, 4-8 parts of all-grass of intermediate peashrub., 5-13 parts of andrographis tenera (nees) O.Kuntze, 4-8 parts of leaves of common perilla, 4-8 parts of herb of pilose gerbera, 4-8 parts of gmelina delavayana P. Dop, 4-8 parts of immature fruits of Pummelo, 4-8 parts of doronicum altaicum pallas, 4-8 parts of siberian wallflower, 4-8 parts of bothrocaryum controuersa (Hemsl.) Poyark. and 4-8 parts of liquorice. The traditional Chinese medicines are combined to perform the efficacy of lung ventilating, promotion of qi circulation, qi tonification, blood nourishment, promotion of feces excretion and stagnancy removal, and the traditional Chinese medicine composition is safe and effective in treatment of qi-blood deficiency type constipation after the PPH for treatment of the hemorrhoidal disease, and can remarkably improve the stool property and relieve the blocking feeling of the anus, feeling of labored defecation, tenesmus, pain during defecation and other constipation symptoms.

Description

A kind of Chinese medicine composition for the treatment of the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid

Technical field

The invention belongs to medical art, be specifically related to a kind of Chinese medicine composition for the treatment of the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid.

Background technology

Hemorrhoid are anal and intestinal diseases very common in daily life, and sickness rate is obvious ascendant trend in recent years.Its main clinical manifestation is deviate from and has blood in stool for the anus thing that swells during stool, and morbidity is early stage through expectant treatment, and most of symptom can improve.If hemorrhoid disease is developed to three, the fourth phase time, expectant treatment then seems unable to do what one wishes, usually needs operative treatment.For the second stage of internal hemorrhoid of repeatedly having blood in stool and three, fourth phase mixed hemorrhoid, modus operandi the most frequently used clinically is at present mucosa ring cutting anastomosis (PPH) in anastomat hemorrhoid.This operation, by mucosa in circular resection hemorrhoid and part submucosa tissue, both can retain anus pad normal physiological function, obviously can improve again blood stasis and deviate from and the symptom such as to have blood in stool, clinical efficacy has demonstrated splendid curative effect.But because a variety of causes causes feces constipated and be difficult to discharge at rectum inner product, feces after operation in patients, often the symptom such as to feel not to the utmost with rectal tenesmus pain, abdominal distention, defecation, also easily therefore cause various complication.Can cause Anastomotic bleeding, edema as squatted for a long time, overexerting, severe patient also can make anastomosis staple come off too early, causes massive hemorrhage, even causes life danger, brings very large impact to the recovery of patient's anus art mouth.Therefore, treatment mixed hemorrhoid postoperative constipation, can reduce the generation of postoperative anal edema and proctalgia, promotes that art mouth recovers, most important to the guarantee of operative effect.

For the treatment of the sick postoperative constipation of hemorrhoid, modern medicine many employings lactulose oral solution is oral waits charthartic, or helping patient's relieving constipation by coloclysis, local irritant method such as plug anus etc., the method for motherland's medical science then multiplex loosening bowel to relieve constipation, it is not satisfactory that these methods can obtain certain curative effect.

Summary of the invention

Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine composition for the treatment of the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid.

The present invention is achieved through the following technical solutions:

Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid, be made up of the Chinese medicine of following weight portion:

Holostemma annulare (Roxb.) K. Schum 4-8 part, Tibet Herba Incarvilleae sinensis 4-8 part, Pedicularis rex C. B. Clarke ex Maxim. 4-8 part, Radix Polygalae fallacis 4-8 part, Ficus fulva Reinw. 4-8 part, lucky subtree 4-8 part, Fructus Mori 4-8 part, wild flax 4-8 part, Herba Caraganae intermediae 4-8 part, spend Herba Andrographis 5-13 part, Folium Perillae Frutescentis 4-8 part, Herba Gerberae Piloselloidis 4-8 part, short person Radix Dichroae 4-8 part, Fructus Citri tomentosae Immaturus 4-8 part, A Ertai doronicum stenoglossum (doronicum) 4-8 part, Flos cheiranthi cheiri 4-8 part, Cornus controversa fruit 4-8 part, Radix Glycyrrhizae 4-8 part in vain.

Preferably, the Chinese medicine composition of the sick PPH postoperative constipation of above-mentioned treatment deficiency of qi and blood type hemorrhoid, is made up of the Chinese medicine of following weight portion:

Holostemma annulare (Roxb.) K. Schum 5-7 part, Tibet Herba Incarvilleae sinensis 5-7 part, Pedicularis rex C. B. Clarke ex Maxim. 5-7 part, Radix Polygalae fallacis 5-7 part, Ficus fulva Reinw. 5-7 part, lucky subtree 5-7 part, Fructus Mori 5-7 part, wild flax 5-7 part, Herba Caraganae intermediae 5-7 part, spend Herba Andrographis 7-11 part, Folium Perillae Frutescentis 5-7 part, Herba Gerberae Piloselloidis 5-7 part, short person Radix Dichroae 5-7 part, Fructus Citri tomentosae Immaturus 5-7 part, A Ertai doronicum stenoglossum (doronicum) 5-7 part, Flos cheiranthi cheiri 5-7 part, Cornus controversa fruit 5-7 part, Radix Glycyrrhizae 5-7 part in vain.

Preferred, the Chinese medicine composition of the sick PPH postoperative constipation of above-mentioned treatment deficiency of qi and blood type hemorrhoid, is made up of the Chinese medicine of following weight portion:

Holostemma annulare (Roxb.) K. Schum 6 parts, Tibet Herba Incarvilleae sinensis 6 parts, Pedicularis rex C. B. Clarke ex Maxim. 6 parts, Radix Polygalae fallacis 6 parts, Ficus fulva Reinw. 6 parts, lucky subtree 6 parts, Fructus Mori 6 parts, wild flax 6 parts, Herba Caraganae intermediae 6 parts, spend in vain Herba Andrographis 9 parts, Folium Perillae Frutescentis 6 parts, Herba Gerberae Piloselloidis 6 parts, short person Radix Dichroae 6 parts, Fructus Citri tomentosae Immaturus 6 parts, A Ertai doronicum stenoglossum (doronicum) 6 parts, Flos cheiranthi cheiri 6 parts, Cornus controversa fruit 6 parts, 6 parts, Radix Glycyrrhizae.

The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.

The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.

The indication of Chinese medicine of the present invention: be used for the treatment of the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid.

The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.

In Chinese medicine composition of the present invention,

Holostemma annulare (Roxb.) K. Schum another name comparatively cuts rattan, is the Herb of dicotyledon medicine asclepiadaceae plant Holostemma annulare (Roxb.) K. Schum Holostemmaannulare (Roxb.) K.Sc-hum. [AsclepiasannularisRoxb].Sweet in the mouth; Property is put down.Return liver; Spleen channel.Function benefiting QI and nourishing blood; To stimulate the menstrual flow stimulating milk secretion.Main puerperal asthenia; Puerperal hypogalactia.

Tibet Herba Incarvilleae sinensis another name Herba Incarvilleae sinensis, for Bignoniaceae plant hides root and the seed of POLO flower IncaruilleayounghusbandiiSprague..Sweet in the mouth; Light; Warm in nature.Function benefiting QI and nourishing blood.Main prolonged illness is weak; Puerperal, breast was few; Dizzy; Anemia.

Pedicularis rex C. B. Clarke ex Maxim. is the root of goatweed Pedicularis rex.Taste is micro-sweet, cool in nature.Function benefiting vital QI and blood, invigorating spleen to remove dampness.

Radix Polygalae fallacis is called the large Radix Polygalae of Hemerocallis citrina Baroni, Radix polygalae arillatae, DIAOHUANG, is hung upside down Hemerocallis citrina Baroni, derives from Polygalaceae polygala Radix Polygalae fallacis PolygalaaureocaudaDunn, is used as medicine with root.Sweet in the mouth, micro-hardship, property is put down.Function benefiting vital QI and blood, invigorating spleen to remove dampness, promoting blood flow to regulate menstruation.For body is empty after being ill, soreness of waist and knee joint, traumatic injury, icterohepatitis, oedema due to nephritis, uterine prolapse, leucorrhea, menoxenia.

The Ficus fulva Reinw. another name tiger palm, crow wind, amnesty mother-in-law tree, hair, derive from Moraceae Ficus fulva Reinw. FicusfulvaReiuw., be used as medicine with root bark.Sweet in the mouth, property is put down.Function invigorating the spleen and benefiting QI, promoting blood circulation by removing wind.Curing mainly deficient qi and blood, uterine prolapse, proctoptosis, edema, rheumatic arthralgia, has loose bowels in loose stool.

The anxious rotten scarabaeidae of lucky subtree another name, copper hoop is loose, shoulder pole is wooden, child's fist, prince wife Xun fiber crops, cotton rib, the precious leaves of two cracking, the moon pearlite layer, Ge Mama, whistle youngster's dish, Ge cypress numb Grewia biloba G.Don, version cylinder bavin, be Tiliaceae plant little Hua bilobed grewia GrewiabilobaG.Donvar.parviflora (Bunge) Hand.Mazz. [G.parvifloraBunge; G.chanetiiLevl.] branch and leaf.Sweet in the mouth; Bitter; Warm in nature.Function invigorating the spleen and benefiting QI; Expelling wind and removing dampness.Main infantile malnutrition; Gastral cavity abdomen 4 distension; Proctoptosis; Woman woman metrorrhagia; Leukorrhagia; Rheumatic arthralgia.

Fructus Mori another name Mulberry reality, Shen, black mulberry, civil and military real, black mulberry, Mulberry Fructus Jujubae, Fructus Mori, Sang Li, sorosis are the fruit ear of moraceae plants Mulberry MorusalbaL..Sweet in the mouth; Acid; Cold in nature.Return liver; Kidney channel.Function nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.

Wild flax calls Caulis et Folium Lini, Herba Violae dissectae, derives from flax family (Linaceae) linum Herba stellariae mediae Caulis et Folium Lini LinumstellarioidesPlanch., is used as medicine with aerial parts and seed.Sweet in the mouth, property is put down.Function blood enriching and dryness moistening, removing toxic substances of dispeling the wind.For blood deficiency and constipation, skin pruritus, urticaria, sore swollen toxin.

Herba Caraganae intermediae is the herb of leguminous plant Caragana intermedia.Sweet, temperature." soft science in China medicinal plants ": " nourishing YIN and benefiting blood."

Spending Herba Andrographis in vain is acanthaceous plant palpus medicinal herbs Andrographislaxiflora (BI.) Lindau [A.tenera (Nees) O.Kuntze; HaplanthusteneraNees] herb.Acrid in the mouth; Bitter; Cool in nature.Function is fallen apart wind heat; Lung qi dispersing gas; Adjust the intestines and stomach.Main cold, fever; Lung-heat cough with asthma; Vomiting; Have loose bowels, constipation etc.

Folium Perillae Frutescentis calls weak leaf, is the leaf of labiate common perilla Perpillafrutescens (L.) Britt..Acrid in the mouth; Warm in nature.Return lung; Spleen channel.Function dispelling wind and ventilating the lung; Regulate the flow of vital energy and help digestion, solving toxin of fish and crab.Main cold; Cough and asthma; Gastral cavity abdominal distention is vexed; Accumulation of food in the stomach and intes tine due to indigestion; Vomit and diarrhoea; Cold-dysentery; Middle fish Eriocheir sinensis poison; Man's swelling of the vulva; Limb edema due to disorder of QI poison; Snake bite and insect sting.

Herba Gerberae Piloselloidis calls little Lycoris radiata, Herba Veronicae, Ainsliaea fragrans Champ., hair rumor, calm automatic grass, pastes Cortex schizophragmatis integrifolii radicis, YIZHUXIANG, white-browed, one, crown grass, pastes ground and disappears, Ba Dixiang, four skin perfume, Man Dixiang, throws oneself on the ground old, and sky wick, lock ground are brave.For the herb of feverfew Herba Gerberae Piloselloidis.Bitter in the mouth is pungent, and property is put down.Function lung qi dispersing, cough-relieving, diaphoresis, diuretic, circulation of qi promoting, invigorates blood circulation.Control the cough due to common cold, asthma, edema, distension, urinary obstruction, food stagnation of child, married woman's amenorrhea, traumatic injury, carbuncle, furuncle, multiple abscess.

Short person Radix Dichroae calls wooden Radix Codonopsis lanceolatae, is the root of Verbenaceae Gmelina delavayana P. Dop GmelinadelauayanaP.Dop [G.montanaW.W.Smith].Acrid in the mouth; Warm in nature.Function circulation of qi promoting; Removing food stagnancy, preventing the attack (or recurrence) of malaria.Main stagnation of QI due to dyspepsia; Abdominal distention; Chronic malaria.

Fructus Citri tomentosae Immaturus another name Fructus Citri tangerinae pearl, Fructus Citri tangerinae tire.For rutaceae Citrus grandis Citusgrandis(L.) the immature fruit of Osbeckvar.tomentosaHort..Sour in the mouth; Bitter; Temperature.Return liver; Spleen; Stomach warp.Function circulation of qi promoting intestinal stasis relieving.Main eating accumulation; Lump in the abdomen.

A Ertai doronicum stenoglossum (doronicum) another name Herba Asteris Flaccidi, Herba Cremanthodii hookerii, derive from Compositae A Ertai doronicum stenoglossum (doronicum) DoronicumaltaicumPallas [CremanthodiumcalotumDiels], with all herbal medicine.Sweet in the mouth, hardship, warm in nature.Function expelling phlegm for arresting cough, the chest stuffiness relieving promoting the circulation of QI.Cure mainly phlegm dyspnea cough.

Flos cheiranthi cheiri is Cruciferae Flos cheiranthi cheiri CheiranthuscheiriL. plant fragrant flower.Sweet in the mouth; Property is put down.Return large intestine; Kidney; Liver Channel.Function loosening bowel to relieve constipation; Stimulate the menstrual flow.Main constipation; Menoxenia; Amenorrhea; Dysmenorrhea.

Cornus controversa fruit is the fruit of Cornaceae plant Cornus controversa Bothrocaryumcontrouersa (Hemsl.) Poyark..Bitter in the mouth; Cool in nature.Function heat-clearing and toxic substances removing; Loosening bowel to relieve constipation; Drive ascarid.Main hepatitis; Dryness of the intestine constipation; Ascariasis.

Radix Glycyrrhizae is sweet, flat.GUIXIN, lung, spleen, stomach warp.Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.

Chinese medicine think constipation and deficiency of qi and blood in close relations, then large intestine conduction is unable for the deficiency of vital energy, just lower unable, and defecation time is extended, formation constipation.Blood deficiency then large intestine is not flourish, and intestinal loses profit, constipation with dry stool, and just lower difficulty, forms constipation.As " Required Readings for Medical Professionals constipation " is said: " more have old body fluid to dry up, married woman's exhaustion of blood in puerperal, and diaphoresis diuresis, vim and vigour are not multiple after being ill, all can be constipated." in addition, Chinese medicine is thought " the lung and the large intestine being interior-exteriorly related "." the secret allusion quotation opinion of Plain Questions LINGLAN " cloud: " large intestine person, the official preached change and here ".Large intestine major function is conduction waste matter it being excreted, right the lung and the large intestine being interior-exteriorly related, and lung meridian and the mutual network of the large intesting channel of Hand-Yangming belong to, and function falls in the Xuan Fasu that the conduction function of large intestine depends on lung qi.Lung qi is respectful to fall, and large intestine internal organs gas falls thereupon, poor Bai Qianhang.The lung being the upper source of fluids, impairment of dispersing and descending function of the lung, water liquid can not moisten intestinal, then poor cypress is involved and abstruse is difficult to walk.Waste matter walks to large intestine end, and lung qi a surname send out, and carry kettle and take off lid, poor cypress draws.Theoretical based on this, " ancient Chinese medical classics essential ideas " points out treatment " reason stool must adjust lung qi also ".Qing Dynasty's YE Tian shi is also sayed " the main the whole body gasification of lung " at "guide to clinical practice with medical record", and advocate that part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels pathological changes is when controlling from part of the body cavity above the diaphragm housing the heart and lungs opinion, must declare at upper lung qi, be so incensed that logical at purgation internal organs, waste matter is easy, is called " carry kettle and take off lid " method.Main and the impairment of dispersing and descending function of the lung of the pathogenesis of the sick PPH postoperative constipation of hemorrhoid, deficiency of qi and blood is relevant, and treatment is taken in lung qi dispersing circulation of qi promoting, benefiting QI and nourishing blood, relieving constipation intestinal stasis relieving.

Chinese medicine composition of the present invention, its prescription mechanism is as follows:

Monarch drug: Holostemma annulare (Roxb.) K. Schum, Tibet Herba Incarvilleae sinensis merit are with benefiting QI and nourishing blood;

Ministerial drug: Pedicularis rex C. B. Clarke ex Maxim., Radix Polygalae fallacis merit are with benefiting vital QI and blood;

Adjuvant drug: Ficus fulva Reinw., lucky subtree merit are with invigorating the spleen and benefiting QI, and QI and blood homology, arrogant then blood is prosperous.Fructus Mori, wild flax, Herba Caraganae intermediae merit are moisturized with nourishing YIN and benefiting blood.Spend Herba Andrographis, Folium Perillae Frutescentis, Herba Gerberae Piloselloidis merit in vain to declare loose lung qi, adjust the intestines and stomach.Short person Radix Dichroae, Fructus Citri tomentosae Immaturus merit are with circulation of qi promoting intestinal stasis relieving; A Ertai doronicum stenoglossum (doronicum) merit is with the chest stuffiness relieving promoting the circulation of QI; Flos cheiranthi cheiri, Cornus controversa fruit merit are with loosening bowel to relieve constipation.

Make medicine: Radix Glycyrrhizae merit is with coordinating the actions of various ingredients in a prescription.

We's compatibility is reasonable, all medicines share, play lung qi dispersing circulation of qi promoting altogether, benefiting QI and nourishing blood, the effect of relieving constipation intestinal stasis relieving, sick PPH postoperative constipation (deficiency of qi and blood type) for the treatment of hemorrhoid is safe and effective, obviously can improve stool, alleviates the constipation symptom such as anus blocking sense, the sense of defecation effort, tenesmus sense and defecation pain.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.

Embodiment 1

Holostemma annulare (Roxb.) K. Schum 6g, Tibet Herba Incarvilleae sinensis 6g, Pedicularis rex C. B. Clarke ex Maxim. 6g, Radix Polygalae fallacis 6g, Ficus fulva Reinw. 6g, lucky subtree 6g, Fructus Mori 6g, wild flax 6g, Herba Caraganae intermediae 6g, spend in vain Herba Andrographis 9g, Folium Perillae Frutescentis 6g, Herba Gerberae Piloselloidis 6g, short person Radix Dichroae 6g, Fructus Citri tomentosae Immaturus 6g, A Ertai doronicum stenoglossum (doronicum) 6g, Flos cheiranthi cheiri 6g, Cornus controversa fruit 6g, Radix Glycyrrhizae 6g.

Embodiment 2

Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid, each crude drug weight proportion is as follows:

Holostemma annulare (Roxb.) K. Schum 5g, Tibet Herba Incarvilleae sinensis 5g, Pedicularis rex C. B. Clarke ex Maxim. 5g, Radix Polygalae fallacis 5g, Ficus fulva Reinw. 5g, lucky subtree 5g, Fructus Mori 5g, wild flax 5g, Herba Caraganae intermediae 5g, spend in vain Herba Andrographis 7g, Folium Perillae Frutescentis 5g, Herba Gerberae Piloselloidis 5g, short person Radix Dichroae 5g, Fructus Citri tomentosae Immaturus 5g, A Ertai doronicum stenoglossum (doronicum) 5g, Flos cheiranthi cheiri 5g, Cornus controversa fruit 5g, Radix Glycyrrhizae 5g.

Embodiment 3

Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid, each crude drug weight proportion is as follows:

Holostemma annulare (Roxb.) K. Schum 7g, Tibet Herba Incarvilleae sinensis 7g, Pedicularis rex C. B. Clarke ex Maxim. 7g, Radix Polygalae fallacis 7g, Ficus fulva Reinw. 7g, lucky subtree 7g, Fructus Mori 7g, wild flax 7g, Herba Caraganae intermediae 7g, spend in vain Herba Andrographis 11g, Folium Perillae Frutescentis 7g, Herba Gerberae Piloselloidis 7g, short person Radix Dichroae 7g, Fructus Citri tomentosae Immaturus 7g, A Ertai doronicum stenoglossum (doronicum) 7g, Flos cheiranthi cheiri 7g, Cornus controversa fruit 7g, Radix Glycyrrhizae 7g.

Embodiment 4

Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid, each crude drug weight proportion is as follows:

Holostemma annulare (Roxb.) K. Schum 8g, Tibet Herba Incarvilleae sinensis 8g, Pedicularis rex C. B. Clarke ex Maxim. 8g, Radix Polygalae fallacis 8g, Ficus fulva Reinw. 8g, lucky subtree 8g, Fructus Mori 8g, wild flax 8g, Herba Caraganae intermediae 8g, spend in vain Herba Andrographis 13g, Folium Perillae Frutescentis 8g, Herba Gerberae Piloselloidis 8g, short person Radix Dichroae 8g, Fructus Citri tomentosae Immaturus 8g, A Ertai doronicum stenoglossum (doronicum) 8g, Flos cheiranthi cheiri 8g, Cornus controversa fruit 8g, Radix Glycyrrhizae 8g.

Embodiment 5

Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid, each crude drug weight proportion is as follows:

Holostemma annulare (Roxb.) K. Schum 4g, Tibet Herba Incarvilleae sinensis 4g, Pedicularis rex C. B. Clarke ex Maxim. 4g, Radix Polygalae fallacis 4g, Ficus fulva Reinw. 4g, lucky subtree 4g, Fructus Mori 4g, wild flax 4g, Herba Caraganae intermediae 4g, spend in vain Herba Andrographis 5g, Folium Perillae Frutescentis 4g, Herba Gerberae Piloselloidis 4g, short person Radix Dichroae 4g, Fructus Citri tomentosae Immaturus 4g, A Ertai doronicum stenoglossum (doronicum) 4g, Flos cheiranthi cheiri 4g, Cornus controversa fruit 4g, Radix Glycyrrhizae 4g.

Carried out clinical pharrnacokinetics test to Chinese medicine composition of the present invention, Details as Follows:

1. data and method

1.1 object of study

Choose mucosa ring cutting anastomosis (PPH) constipation afterwards (deficiency of qi and blood type) patient 160 example in the sick anastomat hemorrhoid of hemorrhoid.

1.2 diagnostic criteria

With reference to " new Chinese medicine guideline of clinical investigations ", deficiency of qi and blood type constipation: disease is seen: constipation with dry stool, discharge difficulty, but face lavatory difficult defecation, the side of earning need be exerted and go out, bring in sweating and shortness of breath, weak after an action of the bowels, have a delicate constitution, lusterless complexion, pallor Mental fatigue, shortness of breath and palpitation, forgetful, lip color is light, the tired lazyness speech of limb, pale tongue with white fur, thready and weak pulse.

1.3 inclusive criteria

(1) hemorrhoid row PPH operator;

(2) postoperative constipation meets deficiency of qi and blood type tcm diagnosis standard person;

(3) age is in 18-75 year;

(4) this experimenter is added voluntarily.

1.3 exclusion standard

(1) diagnostic criteria and inclusive criteria person is not met;

(2) age is less than 18 years old or is greater than 75 years old person, conceived and suckling person;

(3) preoperative have prolonged constipation or diarrhoea person;

(4) with other anal and intestinal diseases as perianal abscess, anal fistula, tripe fistula, hide hair hole, condyloma acuminatum etc.; Be associated with malignant tumor person; Be associated with inflammatory bowel patient;

(5) to our drug allergy person;

(6) compliance difference person, psychotic;

1.4 Therapeutic Method

Give the Chinese medicine of the embodiment of the present invention 1, be decocted in water for oral dose, every day potion, sooner or later sub-service, is used in conjunction 3d.

1.5 observation index

(1) constipation symptom scoring before and after treatment: this scoring comprises the sense of defecation effort, tenesmus sense, anus block sense, defecation pain, every day defecation frequency, each 7 aspects such as defecation time, feces shape, be labeled as 0 to 3 point according to the degree from light to heavy.(2) stool integration: 1 type is that lump is dispersed in shape just (1 point), 2 types are lump lumps just (2 points), 3 types are that slivering has crackle shape just (3 points), 4 types are the soft shape of slivering light just (4 points), 5 types are flexible glue shape just (5 points), 6 types are mushy stool (6 points), and 7 types are rare watery stool (7 points).(3) defecation pain scores: the digitized representation pain in various degree of visual analogue scales, 0 is painless, and 10 for have an intense pain most, allow patient iris out voluntarily numeral that one can represent its pain.

1.6 the standard of curative effect evaluation

Curative effect is judged: the calculating of integrated value change is according to formula below: integration x100% before constipation symptom therapeutic index (n)=(before treatment the rear integration of integration-treatment)/treatment according to integration method.

Clinical recovery: constipation clinical symptoms, sign disappear or the recovery from illness that substantially disappears, n >=90%

Effective: constipation clinical symptoms, sign are obviously improved, 66.7%≤n<90%

Effective: constipation clinical symptoms, sign all take a favorable turn, 33.3%≤n<66.7%

Invalid: constipation clinical symptoms, sign are all not improved, even increase the weight of, n<33.3%.

1.6 statistical method

Application SPSS14.0 statistical software carries out statistical analysis, enumeration data X 2 test, and measurement data adopts t inspection, and P<0.05 represents that difference has statistical significance.

2. result

Constipation symptom integral contrast before and after 2.1 treatments

Before treatment, constipation symptom integration is (18.76 ± 4.76) point, and drop to after treatment (2.45 ± 0.31) point, difference has statistical significance (t=4.176, P<0.05).

Stool integral contrast before and after 2.2 treatments

Before treatment, stool integration is (2.24 ± 0.46) point, and rise to after treatment (5.97 ± 1.53) point, difference has statistical significance (t=4.652, P<0.05).

Defecation pain integral contrast before and after 2.3 treatments

Before treatment, defecation pain integration is (5.65 ± 0.93) point, and drop to after treatment (0.82 ± 0.12) point, difference has statistical significance (t=4.983, P<0.05).

2.4 clinical efficacy

160 routine patients cure 148 examples, effective 10 examples, effective 2 examples, invalid 0 example, cure rate 92.5%, total obvious effective rate 98.75%, total effective rate 100%.

Claims (3)

1. treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of qi and blood type hemorrhoid, be made up of the Chinese medicine of following weight portion:

Holostemma annulare (Roxb.) K. Schum 4-8 part, Tibet Herba Incarvilleae sinensis 4-8 part, Pedicularis rex C. B. Clarke ex Maxim. 4-8 part, Radix Polygalae fallacis 4-8 part, Ficus fulva Reinw. 4-8 part, lucky subtree 4-8 part, Fructus Mori 4-8 part, wild flax 4-8 part, Herba Caraganae intermediae 4-8 part, spend Herba Andrographis 5-13 part, Folium Perillae Frutescentis 4-8 part, Herba Gerberae Piloselloidis 4-8 part, short person Radix Dichroae 4-8 part, Fructus Citri tomentosae Immaturus 4-8 part, A Ertai doronicum stenoglossum (doronicum) 4-8 part, Flos cheiranthi cheiri 4-8 part, Cornus controversa fruit 4-8 part, Radix Glycyrrhizae 4-8 part in vain.

2. the Chinese medicine composition of the sick PPH postoperative constipation for the treatment of deficiency of qi and blood type hemorrhoid according to claim 1, is characterized in that, be made up of the Chinese medicine of following weight portion:

Holostemma annulare (Roxb.) K. Schum 5-7 part, Tibet Herba Incarvilleae sinensis 5-7 part, Pedicularis rex C. B. Clarke ex Maxim. 5-7 part, Radix Polygalae fallacis 5-7 part, Ficus fulva Reinw. 5-7 part, lucky subtree 5-7 part, Fructus Mori 5-7 part, wild flax 5-7 part, Herba Caraganae intermediae 5-7 part, spend Herba Andrographis 7-11 part, Folium Perillae Frutescentis 5-7 part, Herba Gerberae Piloselloidis 5-7 part, short person Radix Dichroae 5-7 part, Fructus Citri tomentosae Immaturus 5-7 part, A Ertai doronicum stenoglossum (doronicum) 5-7 part, Flos cheiranthi cheiri 5-7 part, Cornus controversa fruit 5-7 part, Radix Glycyrrhizae 5-7 part in vain.

3. the Chinese medicine composition of the sick PPH postoperative constipation for the treatment of deficiency of qi and blood type hemorrhoid according to claim 2, is characterized in that, be made up of the Chinese medicine of following weight portion:

Holostemma annulare (Roxb.) K. Schum 6 parts, Tibet Herba Incarvilleae sinensis 6 parts, Pedicularis rex C. B. Clarke ex Maxim. 6 parts, Radix Polygalae fallacis 6 parts, Ficus fulva Reinw. 6 parts, lucky subtree 6 parts, Fructus Mori 6 parts, wild flax 6 parts, Herba Caraganae intermediae 6 parts, spend in vain Herba Andrographis 9 parts, Folium Perillae Frutescentis 6 parts, Herba Gerberae Piloselloidis 6 parts, short person Radix Dichroae 6 parts, Fructus Citri tomentosae Immaturus 6 parts, A Ertai doronicum stenoglossum (doronicum) 6 parts, Flos cheiranthi cheiri 6 parts, Cornus controversa fruit 6 parts, 6 parts, Radix Glycyrrhizae.