CN105168728A - Traditional Chinese medicine composition for treating yin-fluid and blood deficiency type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of hemorrhoidal disease - Google Patents

Traditional Chinese medicine composition for treating yin-fluid and blood deficiency type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of hemorrhoidal disease Download PDF

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CN105168728A
CN105168728A CN201510636875.5A CN201510636875A CN105168728A CN 105168728 A CN105168728 A CN 105168728A CN 201510636875 A CN201510636875 A CN 201510636875A CN 105168728 A CN105168728 A CN 105168728A
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王立国
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Jinan Bangwen Pharmaceutical Technology Co Ltd
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Abstract

The invention belongs to the technical field of medicines, and particularly relates to traditional Chinese medicine composition for treating yin-fluid and blood deficiency type constipation after a PPH (procedure for prolapse and hemorrhoids) for treatment of a hemorrhoidal disease. The traditional Chinese medicine composition comprises traditional Chinese medicines in parts by weight as follows: 4-8 parts of all-grass of intermediate peashrub, 4-8 parts of mulberry fruits, 4-8 parts of rugosa paraphlomis, 4-8 parts of Fimbristylis rigiduta Nees, 4-8 parts of Linum stellarioides Planch., 4-8 parts of ficus esquiroliana,4-8 parts of roots of bilobed grewia, 5-13 parts of andrographis tenera (Nees) O.Kuntze, 4-8 parts of leaves of common perilla, 4-8 parts of herb of pilose gerbera, 4-8 parts of gmelina delavayana P. Dop, 4-8 parts of immature fruits of Pummelo, 4-8 parts of doronicum altaicum pallas, 4-8 parts of siberian wallflower, 4-8 parts of bothrocaryum controuersa (Hemsl.) Poyark. and 4-8 parts of liquorice. The traditional Chinese medicines are combined to perform the efficacy of lung ventilating, promotion of qi circulation, yin and blood nourishment, promotion of feces excretion and stagnation removal, and the traditional Chinese medicine composition is safe and effective in treatment of yin-fluid and blood deficiency type constipation after the PPH for treatment of the hemorrhoidal disease and can remarkably improve the stool property and relieve the blocking feeling of the anus, feeling of labored defecation, tenesmus, pain during defecation and other constipation symptoms.

Description

A kind of Chinese medicine composition for the treatment of the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine composition for the treatment of the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid.
Background technology
Hemorrhoid are anal and intestinal diseases very common in daily life, and sickness rate is obvious ascendant trend in recent years.Its main clinical manifestation is deviate from and has blood in stool for the anus thing that swells during stool, and morbidity is early stage through expectant treatment, and most of symptom can improve.If hemorrhoid disease is developed to three, the fourth phase time, expectant treatment then seems unable to do what one wishes, usually needs operative treatment.For the second stage of internal hemorrhoid of repeatedly having blood in stool and three, fourth phase mixed hemorrhoid, modus operandi the most frequently used clinically is at present mucosa ring cutting anastomosis (PPH) in anastomat hemorrhoid.This operation, by mucosa in circular resection hemorrhoid and part submucosa tissue, both can retain anus pad normal physiological function, obviously can improve again blood stasis and deviate from and the symptom such as to have blood in stool, clinical efficacy has demonstrated splendid curative effect.But because a variety of causes causes feces constipated and be difficult to discharge at rectum inner product, feces after operation in patients, often the symptom such as to feel not to the utmost with rectal tenesmus pain, abdominal distention, defecation, also easily therefore cause various complication.Can cause Anastomotic bleeding, edema as squatted for a long time, overexerting, severe patient also can make anastomosis staple come off too early, causes massive hemorrhage, even causes life danger, brings very large impact to the recovery of patient's anus art mouth.Therefore, treatment mixed hemorrhoid postoperative constipation, can reduce the generation of postoperative anal edema and proctalgia, promotes that art mouth recovers, most important to the guarantee of operative effect.
For the treatment of the sick postoperative constipation of hemorrhoid, modern medicine many employings lactulose oral solution is oral waits charthartic, or helping patient's relieving constipation by coloclysis, local irritant method such as plug anus etc., the method for motherland's medical science then multiplex loosening bowel to relieve constipation, it is not satisfactory that these methods can obtain certain curative effect.
Summary of the invention
Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine composition for the treatment of the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid, be made up of the Chinese medicine of following weight portion:
Herba Caraganae intermediae 4-8 part, Fructus Mori 4-8 part, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 4-8 part, hair honeybee 4-8 part, wild flax 4-8 part, Ficus fulva Reinw. 4-8 part, lucky subtree 4-8 part, spend Herba Andrographis 5-13 part, Folium Perillae Frutescentis 4-8 part, Herba Gerberae Piloselloidis 4-8 part, short person Radix Dichroae 4-8 part, Fructus Citri tomentosae Immaturus 4-8 part, A Ertai doronicum stenoglossum (doronicum) 4-8 part, Flos cheiranthi cheiri 4-8 part, Cornus controversa fruit 4-8 part, Radix Glycyrrhizae 4-8 part in vain.
Preferably, the Chinese medicine composition of the sick PPH postoperative constipation of above-mentioned treatment deficiency of both YIN-fluid and blood type hemorrhoid, is made up of the Chinese medicine of following weight portion:
Herba Caraganae intermediae 5-7 part, Fructus Mori 5-7 part, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 5-7 part, hair honeybee 5-7 part, wild flax 5-7 part, Ficus fulva Reinw. 5-7 part, lucky subtree 5-7 part, spend Herba Andrographis 7-11 part, Folium Perillae Frutescentis 5-7 part, Herba Gerberae Piloselloidis 5-7 part, short person Radix Dichroae 5-7 part, Fructus Citri tomentosae Immaturus 5-7 part, A Ertai doronicum stenoglossum (doronicum) 5-7 part, Flos cheiranthi cheiri 5-7 part, Cornus controversa fruit 5-7 part, Radix Glycyrrhizae 5-7 part in vain.
Preferred, the Chinese medicine composition of the sick PPH postoperative constipation of above-mentioned treatment deficiency of both YIN-fluid and blood type hemorrhoid, is made up of the Chinese medicine of following weight portion:
Herba Caraganae intermediae 6 parts, Fructus Mori 6 parts, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 6 part, mao honeybee 6 parts, wild flax 6 parts, Ficus fulva Reinw. 6 parts, lucky subtree 6 parts, spend in vain Herba Andrographis 9 parts, Folium Perillae Frutescentis 6 parts, Herba Gerberae Piloselloidis 6 parts, short person Radix Dichroae 6 parts, Fructus Citri tomentosae Immaturus 6 parts, A Ertai doronicum stenoglossum (doronicum) 6 parts, Flos cheiranthi cheiri 6 parts, Cornus controversa fruit 6 parts, 6 parts, Radix Glycyrrhizae.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The indication of Chinese medicine of the present invention: be used for the treatment of the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
In Chinese medicine composition of the present invention,
Herba Caraganae intermediae is the herb of leguminous plant Caragana intermedia.Sweet, temperature." soft science in China medicinal plants ": " nourishing YIN and benefiting blood."
Fructus Mori another name Mulberry reality, Shen, black mulberry, civil and military real, black mulberry, Mulberry Fructus Jujubae, Fructus Mori, Sang Li, sorosis are the fruit ear of moraceae plants Mulberry MorusalbaL..Sweet in the mouth; Acid; Cold in nature.Return liver; Kidney channel.Function nourishing YIN and benefiting blood; Promote the production of body fluid; Intestine moistening.Having a dizzy spell of main deficiency of the liver and kindey and blood deficiency damage of essence; Soreness of waist tinnitus; Early whitening of beard and hair; Insomnia and dreamful sleep; Tianjin wound is thirsty; Quench one's thirst; Dryness of the intestine constipation.
Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu another name 12 Flos Sophoraes are the herb of the false Herba phlomidis of labiate lobule.Sweet in the mouth, property is put down.Function is nourshing Yin and drynsessmoistening prescription, cough-relieving, regulating menstruation.Control consumptive disease to cough, menoxenia.
Hair honeybee another name Herba Roegneriae serotinae, TOUGUFENG, knot strengthen Herba Fimbristylis dichotomae, derive from Cyperaceae Radix Fimbristylis rigidulae FimbristylisrigidulaNees, are used as medicine with root.Sweet in the mouth, cold nature.Function is nourshing Yin and drynsessmoistening prescription, and tonify deficiency benefit is damaged.Cure mainly pulmonary tuberculosis, night sweat, chronic cough, weak dizzy.
Wild flax calls Caulis et Folium Lini, Herba Violae dissectae, derives from flax family (Linaceae) linum Herba stellariae mediae Caulis et Folium Lini LinumstellarioidesPlanch., is used as medicine with aerial parts and seed.Sweet in the mouth, property is put down.Function blood enriching and dryness moistening, removing toxic substances of dispeling the wind.For blood deficiency and constipation, skin pruritus, urticaria, sore swollen toxin.
The Ficus fulva Reinw. another name tiger palm, crow wind, amnesty mother-in-law tree, hair, derive from Moraceae Ficus fulva Reinw. FicusfulvaReiuw., be used as medicine with root bark.Sweet in the mouth, property is put down.Function invigorating the spleen and benefiting QI, promoting blood circulation by removing wind.Curing mainly deficient qi and blood, uterine prolapse, proctoptosis, edema, rheumatic arthralgia, has loose bowels in loose stool.
The anxious rotten scarabaeidae of lucky subtree another name, copper hoop is loose, shoulder pole is wooden, child's fist, prince wife Xun fiber crops, cotton rib, the precious leaves of two cracking, the moon pearlite layer, Ge Mama, whistle youngster's dish, Ge cypress numb Grewia biloba G.Don, version cylinder bavin, Tiliaceae plant little Hua bilobed grewia GrewiabilobaG.Donvar.parviflora (Bunge) Hand.Mazz. [G.parvifloraBunge; G.chanetiiLevl.] branch and leaf.Sweet in the mouth; Bitter; Warm in nature.Function invigorating the spleen and benefiting QI; Expelling wind and removing dampness.Main infantile malnutrition; Gastral cavity abdomen 4 distension; Proctoptosis; Woman woman metrorrhagia; Leukorrhagia; Rheumatic arthralgia.
Spending Herba Andrographis in vain is acanthaceous plant palpus medicinal herbs Andrographislaxiflora (BI.) Lindau [A.tenera (Nees) O.Kuntze; HaplanthusteneraNees] herb.Acrid in the mouth; Bitter; Cool in nature.Function is fallen apart wind heat; Lung qi dispersing gas; Adjust the intestines and stomach.Main cold, fever; Lung-heat cough with asthma; Vomiting; Have loose bowels, constipation etc.
Folium Perillae Frutescentis calls weak leaf, is the leaf of labiate common perilla Perpillafrutescens (L.) Britt..Acrid in the mouth; Warm in nature.Return lung; Spleen channel.Function dispelling wind and ventilating the lung; Regulate the flow of vital energy and help digestion, solving toxin of fish and crab.Main cold; Cough and asthma; Gastral cavity abdominal distention is vexed; Accumulation of food in the stomach and intes tine due to indigestion; Vomit and diarrhoea; Cold-dysentery; Middle fish Eriocheir sinensis poison; Man's swelling of the vulva; Limb edema due to disorder of QI poison; Snake bite and insect sting.
Herba Gerberae Piloselloidis calls little Lycoris radiata, Herba Veronicae, Ainsliaea fragrans Champ., hair rumor, calm automatic grass, pastes Cortex schizophragmatis integrifolii radicis, YIZHUXIANG, white-browed, one, crown grass, pastes ground and disappears, Ba Dixiang, four skin perfume, Man Dixiang, throws oneself on the ground old, and sky wick, lock ground are brave.For the herb of feverfew Herba Gerberae Piloselloidis.Bitter in the mouth is pungent, and property is put down.Function lung qi dispersing, cough-relieving, diaphoresis, diuretic, circulation of qi promoting, invigorates blood circulation.Control the cough due to common cold, asthma, edema, distension, urinary obstruction, food stagnation of child, married woman's amenorrhea, traumatic injury, carbuncle, furuncle, multiple abscess.
Short person Radix Dichroae calls wooden Radix Codonopsis lanceolatae, is the root of Verbenaceae Gmelina delavayana P. Dop GmelinadelauayanaP.Dop [G.montanaW.W.Smith].Acrid in the mouth; Warm in nature.Function circulation of qi promoting; Removing food stagnancy, preventing the attack (or recurrence) of malaria.Main stagnation of QI due to dyspepsia; Abdominal distention; Chronic malaria.
Fructus Citri tomentosae Immaturus another name Fructus Citri tangerinae pearl, Fructus Citri tangerinae tire.For rutaceae Citrus grandis Citusgrandis(L.) the immature fruit of Osbeckvar.tomentosaHort..Sour in the mouth; Bitter; Temperature.Return liver; Spleen; Stomach warp.Function circulation of qi promoting intestinal stasis relieving.Main eating accumulation; Lump in the abdomen.
A Ertai doronicum stenoglossum (doronicum) another name Herba Asteris Flaccidi, Herba Cremanthodii hookerii, derive from Compositae A Ertai doronicum stenoglossum (doronicum) DoronicumaltaicumPallas [CremanthodiumcalotumDiels], with all herbal medicine.Sweet in the mouth, hardship, warm in nature.Function expelling phlegm for arresting cough, the chest stuffiness relieving promoting the circulation of QI.Cure mainly phlegm dyspnea cough.
Flos cheiranthi cheiri is Cruciferae Flos cheiranthi cheiri CheiranthuscheiriL. plant fragrant flower.Sweet in the mouth; Property is put down.Return large intestine; Kidney; Liver Channel.Function loosening bowel to relieve constipation; Stimulate the menstrual flow.Main constipation; Menoxenia; Amenorrhea; Dysmenorrhea.
Cornus controversa fruit is the fruit of Cornaceae plant Cornus controversa Bothrocaryumcontrouersa (Hemsl.) Poyark..Bitter in the mouth; Cool in nature.Function heat-clearing and toxic substances removing; Loosening bowel to relieve constipation; Drive ascarid.Main hepatitis; Dryness of the intestine constipation; Ascariasis.
Radix Glycyrrhizae is sweet, flat.GUIXIN, lung, spleen, stomach warp.Function invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Chinese medicine think constipation and deficiency of both YIN-fluid and blood in close relations, the deficiency of both YIN-fluid and blood ferritic deficiency of YIN; Body fluid deficiency insufficiency of blood; Or puerperal after being ill, cloudy blood deficiency is few; Or lose blood and take antiperspirant by force, impairment of body fluid exhaustion of blood; Or year is high weak, deficiency of YIN-blood; Or the pungent perfume (or spice) of surfeit is scorching, the cloudy blood of loss, all can cause deficiency of both YIN-fluid and blood, blood deficiency then large intestine is not flourish, and cloudy thanks to then large intestine is dry and astringent, and intestinal loses profit, constipation with dry stool, and just lower difficulty, forms constipation.As " Required Readings for Medical Professionals constipation " is said: " more have old body fluid to dry up, married woman's exhaustion of blood in puerperal, and diaphoresis diuresis, vim and vigour are not multiple after being ill, all can be constipated." in addition, Chinese medicine is thought " the lung and the large intestine being interior-exteriorly related "." the secret allusion quotation opinion of Plain Questions LINGLAN " cloud: " large intestine person, the official preached change and here ".Large intestine major function is conduction waste matter it being excreted, right the lung and the large intestine being interior-exteriorly related, and lung meridian and the mutual network of the large intesting channel of Hand-Yangming belong to, and function falls in the Xuan Fasu that the conduction function of large intestine depends on lung qi.Lung qi is respectful to fall, and large intestine internal organs gas falls thereupon, poor Bai Qianhang.The lung being the upper source of fluids, impairment of dispersing and descending function of the lung, water liquid can not moisten intestinal, then poor cypress is involved and abstruse is difficult to walk.Waste matter walks to large intestine end, and lung qi a surname send out, and carry kettle and take off lid, poor cypress draws.Theoretical based on this, " ancient Chinese medical classics essential ideas " points out treatment " reason stool must adjust lung qi also ".Qing Dynasty's YE Tian shi is also sayed " the main the whole body gasification of lung " at "guide to clinical practice with medical record", and advocate that part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels pathological changes is when controlling from part of the body cavity above the diaphragm housing the heart and lungs opinion, must declare at upper lung qi, be so incensed that logical at purgation internal organs, waste matter is easy, is called " carry kettle and take off lid " method.Main and the impairment of dispersing and descending function of the lung of the pathogenesis of the sick PPH postoperative constipation of hemorrhoid, deficiency of both YIN-fluid and blood is relevant, and treatment is taken in lung qi dispersing circulation of qi promoting, nourishing YIN and benefiting blood, relieving constipation intestinal stasis relieving.
Chinese medicine composition of the present invention, its prescription mechanism is as follows:
Monarch drug: spend Herba Andrographis merit in vain with lung qi dispersing gas, tune the intestines and stomach.
Monarch drug: Herba Caraganae intermediae, Fructus Mori merit are with nourishing YIN and benefiting blood;
Ministerial drug: Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu, hair honeybee merit are with nourshing Yin and drynsessmoistening prescription; Wild flax merit is with blood enriching and dryness moistening.
Adjuvant drug: Ficus fulva Reinw., lucky subtree merit are with invigorating the spleen and benefiting QI, and QI and blood homology, arrogant then blood is prosperous.Spend Herba Andrographis, Folium Perillae Frutescentis, Herba Gerberae Piloselloidis merit in vain to declare loose lung qi, adjust the intestines and stomach.Short person Radix Dichroae, Fructus Citri tomentosae Immaturus merit are with circulation of qi promoting intestinal stasis relieving; A Ertai doronicum stenoglossum (doronicum) merit is with the chest stuffiness relieving promoting the circulation of QI; Flos cheiranthi cheiri, Cornus controversa fruit merit are with loosening bowel to relieve constipation.
Make medicine: Radix Glycyrrhizae merit is with coordinating the actions of various ingredients in a prescription.
We's compatibility is reasonable, all medicines share, play lung qi dispersing circulation of qi promoting altogether, nourishing YIN and benefiting blood, the effect of relieving constipation intestinal stasis relieving, sick PPH postoperative constipation (deficiency of both YIN-fluid and blood type) for the treatment of hemorrhoid is safe and effective, obviously can improve stool, alleviates the constipation symptom such as anus blocking sense, the sense of defecation effort, tenesmus sense and defecation pain.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Herba Caraganae intermediae 6g, Fructus Mori 6g, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 6g, hair honeybee 6g, wild flax 6g, Ficus fulva Reinw. 6g, lucky subtree 6g, spend in vain Herba Andrographis 9g, Folium Perillae Frutescentis 6g, Herba Gerberae Piloselloidis 6g, short person Radix Dichroae 6g, Fructus Citri tomentosae Immaturus 6g, A Ertai doronicum stenoglossum (doronicum) 6g, Flos cheiranthi cheiri 6g, Cornus controversa fruit 6g, Radix Glycyrrhizae 6g.
Embodiment 2
Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid, each crude drug weight proportion is as follows:
Herba Caraganae intermediae 5g, Fructus Mori 5g, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 5g, hair honeybee 5g, wild flax 5g, Ficus fulva Reinw. 5g, lucky subtree 5g, spend in vain Herba Andrographis 7g, Folium Perillae Frutescentis 5g, Herba Gerberae Piloselloidis 5g, short person Radix Dichroae 5g, Fructus Citri tomentosae Immaturus 5g, A Ertai doronicum stenoglossum (doronicum) 5g, Flos cheiranthi cheiri 5g, Cornus controversa fruit 5g, Radix Glycyrrhizae 5g.
Embodiment 3
Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid, each crude drug weight proportion is as follows:
Herba Caraganae intermediae 7g, Fructus Mori 7g, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 7g, hair honeybee 7g, wild flax 7g, Ficus fulva Reinw. 7g, lucky subtree 7g, spend in vain Herba Andrographis 11g, Folium Perillae Frutescentis 7g, Herba Gerberae Piloselloidis 7g, short person Radix Dichroae 7g, Fructus Citri tomentosae Immaturus 7g, A Ertai doronicum stenoglossum (doronicum) 7g, Flos cheiranthi cheiri 7g, Cornus controversa fruit 7g, Radix Glycyrrhizae 7g.
Embodiment 4
Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid, each crude drug weight proportion is as follows:
Herba Caraganae intermediae 8g, Fructus Mori 8g, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 8g, hair honeybee 8g, wild flax 8g, Ficus fulva Reinw. 8g, lucky subtree 8g, spend in vain Herba Andrographis 13g, Folium Perillae Frutescentis 8g, Herba Gerberae Piloselloidis 8g, short person Radix Dichroae 8g, Fructus Citri tomentosae Immaturus 8g, A Ertai doronicum stenoglossum (doronicum) 8g, Flos cheiranthi cheiri 8g, Cornus controversa fruit 8g, Radix Glycyrrhizae 8g.
Embodiment 5
Treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid, each crude drug weight proportion is as follows:
Herba Caraganae intermediae 4g, Fructus Mori 4g, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 4g, hair honeybee 4g, wild flax 4g, Ficus fulva Reinw. 4g, lucky subtree 4g, spend in vain Herba Andrographis 5g, Folium Perillae Frutescentis 4g, Herba Gerberae Piloselloidis 4g, short person Radix Dichroae 4g, Fructus Citri tomentosae Immaturus 4g, A Ertai doronicum stenoglossum (doronicum) 4g, Flos cheiranthi cheiri 4g, Cornus controversa fruit 4g, Radix Glycyrrhizae 4g.
Carried out clinical pharrnacokinetics test to Chinese medicine composition of the present invention, Details as Follows:
1. data and method
1.1 object of study
Choose mucosa ring cutting anastomosis (PPH) constipation afterwards (deficiency of both YIN-fluid and blood type) patient 140 example in the sick anastomat hemorrhoid of hemorrhoid.
1.2 diagnostic criteria
With reference to " new Chinese medicine guideline of clinical investigations ", deficiency of both YIN-fluid and blood type constipation: disease is seen: constipation with dry stool, as sheep dung shape, discharge difficulty, emaciated physique, lusterless complexion, shortness of breath and palpitation, dizziness and tinnitus, vexed insomnia, hectic fever night sweat, soreness of waist and knee, forgetful, lip color is light, the few tongue of red tongue, thready and rapid pulse.
1.3 inclusive criteria
(1) hemorrhoid row PPH operator;
(2) postoperative constipation meets deficiency of both YIN-fluid and blood type tcm diagnosis standard person;
(3) age is in 18-75 year;
(4) this experimenter is added voluntarily.
1.3 exclusion standard
(1) diagnostic criteria and inclusive criteria person is not met;
(2) age is less than 18 years old or is greater than 75 years old person, conceived and suckling person;
(3) preoperative have prolonged constipation or diarrhoea person;
(4) with other anal and intestinal diseases as perianal abscess, anal fistula, tripe fistula, hide hair hole, condyloma acuminatum etc.; Be associated with malignant tumor person; Be associated with inflammatory bowel patient;
(5) to our drug allergy person;
(6) compliance difference person, psychotic;
1.4 Therapeutic Method
Give the Chinese medicine composition of the embodiment of the present invention 1, be decocted in water for oral dose, every day potion, sooner or later sub-service, is used in conjunction 3d.
1.5 observation index
(1) constipation symptom scoring before and after treatment: this scoring comprises the sense of defecation effort, tenesmus sense, anus block sense, defecation pain, every day defecation frequency, each 7 aspects such as defecation time, feces shape, be labeled as 0 to 3 point according to the degree from light to heavy.(2) stool integration: 1 type is that lump is dispersed in shape just (1 point), 2 types are lump lumps just (2 points), 3 types are that slivering has crackle shape just (3 points), 4 types are the soft shape of slivering light just (4 points), 5 types are flexible glue shape just (5 points), 6 types are mushy stool (6 points), and 7 types are rare watery stool (7 points).(3) defecation pain scores: the digitized representation pain in various degree of visual analogue scales, 0 is painless, and 10 for have an intense pain most, allow patient iris out voluntarily numeral that one can represent its pain.
1.6 the standard of curative effect evaluation
Curative effect is judged: the calculating of integrated value change is according to formula below: integration x100% before constipation symptom therapeutic index (n)=(before treatment the rear integration of integration-treatment)/treatment according to integration method.
Clinical recovery: constipation clinical symptoms, sign disappear or the recovery from illness that substantially disappears, n >=90%
Effective: constipation clinical symptoms, sign are obviously improved, 66.7%≤n<90%
Effective: constipation clinical symptoms, sign all take a favorable turn, 33.3%≤n<66.7%
Invalid: constipation clinical symptoms, sign are all not improved, even increase the weight of, n<33.3%.
1.6 statistical method
Application SPSS14.0 statistical software carries out statistical analysis, enumeration data X 2 test, and measurement data adopts t inspection, and P<0.05 represents that difference has statistical significance.
2. result
Constipation symptom integral contrast before and after 2.1 treatments
Before treatment, constipation symptom integration is (18.35 ± 4.87) point, and drop to after treatment (2.32 ± 0.27) point, difference has statistical significance (t=4.372, P<0.05).
Stool integral contrast before and after 2.2 treatments
Before treatment, stool integration is (2.21 ± 0.49) point, and rise to after treatment (5.94 ± 1.56) point, difference has statistical significance (t=4.388, P<0.05).
Defecation pain integral contrast before and after 2.3 treatments
Before treatment, defecation pain integration is (5.32 ± 0.87) point, and drop to after treatment (0.86 ± 0.16) point, difference has statistical significance (t=4.983, P<0.05).
2.4 clinical efficacy
140 routine patients cure 127 examples, effective 10 examples, effective 3 examples, invalid 0 example, cure rate 90.7%, total obvious effective rate 97.9%, total effective rate 100%.

Claims (3)

1. treat a Chinese medicine composition for the sick PPH postoperative constipation of deficiency of both YIN-fluid and blood type hemorrhoid, be made up of the Chinese medicine of following weight portion:
Herba Caraganae intermediae 4-8 part, Fructus Mori 4-8 part, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 4-8 part, hair honeybee 4-8 part, wild flax 4-8 part, Ficus fulva Reinw. 4-8 part, lucky subtree 4-8 part, spend Herba Andrographis 5-13 part, Folium Perillae Frutescentis 4-8 part, Herba Gerberae Piloselloidis 4-8 part, short person Radix Dichroae 4-8 part, Fructus Citri tomentosae Immaturus 4-8 part, A Ertai doronicum stenoglossum (doronicum) 4-8 part, Flos cheiranthi cheiri 4-8 part, Cornus controversa fruit 4-8 part, Radix Glycyrrhizae 4-8 part in vain.
2. the Chinese medicine composition of the sick PPH postoperative constipation for the treatment of deficiency of both YIN-fluid and blood type hemorrhoid according to claim 1, is characterized in that, be made up of the Chinese medicine of following weight portion:
Herba Caraganae intermediae 5-7 part, Fructus Mori 5-7 part, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 5-7 part, hair honeybee 5-7 part, wild flax 5-7 part, Ficus fulva Reinw. 5-7 part, lucky subtree 5-7 part, spend Herba Andrographis 7-11 part, Folium Perillae Frutescentis 5-7 part, Herba Gerberae Piloselloidis 5-7 part, short person Radix Dichroae 5-7 part, Fructus Citri tomentosae Immaturus 5-7 part, A Ertai doronicum stenoglossum (doronicum) 5-7 part, Flos cheiranthi cheiri 5-7 part, Cornus controversa fruit 5-7 part, Radix Glycyrrhizae 5-7 part in vain.
3. the Chinese medicine composition of the sick PPH postoperative constipation for the treatment of deficiency of both YIN-fluid and blood type hemorrhoid according to claim 3, is characterized in that, be made up of the Chinese medicine of following weight portion:
Herba Caraganae intermediae 6 parts, Fructus Mori 6 parts, Paraphlomis rugosa (Benth.) Prain var. Coronata (Vant.) C. Y. Wu 6 part, mao honeybee 6 parts, wild flax 6 parts, Ficus fulva Reinw. 6 parts, lucky subtree 6 parts, spend in vain Herba Andrographis 9 parts, Folium Perillae Frutescentis 6 parts, Herba Gerberae Piloselloidis 6 parts, short person Radix Dichroae 6 parts, Fructus Citri tomentosae Immaturus 6 parts, A Ertai doronicum stenoglossum (doronicum) 6 parts, Flos cheiranthi cheiri 6 parts, Cornus controversa fruit 6 parts, 6 parts, Radix Glycyrrhizae.
CN201510636875.5A 2015-09-29 2015-09-29 Traditional Chinese medicine composition for treating yin-fluid and blood deficiency type constipation after PPH (procedure for prolapse and hemorrhoids) for treatment of hemorrhoidal disease Pending CN105168728A (en)

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