CN105168219B - 用于睡眠障碍和其他疾病的方法和组合物 - Google Patents
用于睡眠障碍和其他疾病的方法和组合物 Download PDFInfo
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- CN105168219B CN105168219B CN201510553160.3A CN201510553160A CN105168219B CN 105168219 B CN105168219 B CN 105168219B CN 201510553160 A CN201510553160 A CN 201510553160A CN 105168219 B CN105168219 B CN 105168219B
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
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Landscapes
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| US5643308P | 2008-05-27 | 2008-05-27 | |
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| CN200980128888.4A CN102105059B (zh) | 2008-05-27 | 2009-05-27 | 用于睡眠障碍和其他疾病的方法和组合物 |
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| CN200980128888.4A Active CN102105059B (zh) | 2008-05-27 | 2009-05-27 | 用于睡眠障碍和其他疾病的方法和组合物 |
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| WO2008052139A2 (en) | 2006-10-25 | 2008-05-02 | Somaxon Pharmaceuticals, Inc. | Ultra low dose doxepin and methods of using the same to treat sleep disorders |
| US20110077200A1 (en) * | 2006-12-06 | 2011-03-31 | Somaxon Pharmaceuticals, Inc. | Combination therapy using low-dose doxepin for the improvement of sleep |
| KR102065319B1 (ko) | 2007-03-12 | 2020-01-10 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 치환된 헤테로환 융합 감마-카르볼린 합성 |
| JP5611846B2 (ja) | 2008-03-12 | 2014-10-22 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 置換ヘテロ環縮合ガンマ−カルボリン類固体 |
| CN105168219B (zh) * | 2008-05-27 | 2018-11-20 | 细胞内治疗公司 | 用于睡眠障碍和其他疾病的方法和组合物 |
| ES2585806T3 (es) | 2009-10-23 | 2016-10-10 | Janssen Pharmaceutica N.V. | Octahidropirrolo [3,4-c] pirroles disustituidos como moduladores de receptores de orexina |
| EP2560676B8 (en) * | 2010-04-22 | 2016-10-12 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US8741888B2 (en) * | 2010-11-09 | 2014-06-03 | Carl A. Forest | Sleep aid composition and method |
| JP6050813B2 (ja) * | 2011-07-08 | 2016-12-21 | イーライ リリー アンド カンパニー | 二重作用Ｈ１インバースアゴニスト／５−ＨＴ２Ａアンタゴニストとしての（チエノ［２，３−ｂ］［１，５］ベンゾオキサゼピン−４−イル）ピペラジン−１−イル化合物 |
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| WO2014159720A1 (en) * | 2013-03-13 | 2014-10-02 | The University Of Chicago | Methods and compositions for inhibiting glyoxalase 1 (glo1) |
| WO2014152804A1 (en) * | 2013-03-14 | 2014-09-25 | Hyperion Biotechnology | Methods and compositions for biomarkers of fatigue, fitness and physical performance capacity |
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