CN105145642B - A kind of granular formulation for killing nematode containing fosthiazate - Google Patents
A kind of granular formulation for killing nematode containing fosthiazate Download PDFInfo
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- CN105145642B CN105145642B CN201510697597.4A CN201510697597A CN105145642B CN 105145642 B CN105145642 B CN 105145642B CN 201510697597 A CN201510697597 A CN 201510697597A CN 105145642 B CN105145642 B CN 105145642B
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- fosthiazate
- trichoderma harzianum
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Abstract
The present invention relates to a kind of granular formulation for killing nematode containing fosthiazate, active constituent is made of fosthiazate and trichoderma harzianum, and trichoderma harzianum is set to 100% female medicine with 30,000,000,000 CFU/ grams of female medicines, and the weight ratio of fosthiazate and trichoderma harzianum is 5 90:1, the content of fosthiazate in the composition is 2.5%~15%, and the content of trichoderma harzianum in the composition is 0.3 hundred million CFU/ grams~1.5 hundred million CFU/ grams.The present invention has medicament high-efficiency low-toxicity, compares carbofuran, and medicament is substantially reduced the toxicity of people and animals, avoids the risk of production and application person poultry poisoning.Active constituent is synergistic, uses in the reasonable scope, can reduce the amount of application of each single dose, advantageously reduces drug cost and reduces environmental pollution.Trichoderma harzianum can improve the microenvironment of soil, keep plant root growth healthier, have preferable control effect to root rot, southern blight, samping off, the damping-off in soil-borne disease.
Description
Technical field
The present invention relates to technical field of pesticide, specifically a kind of granular formulation for killing nematode containing fosthiazate.
Background technology
Root-knot nematode and cyst nematode, are two most heavy class nematodes of the harm to agricultural production, and the crop of main harm has
Cucumber, peanut, rice, soybean, wheat, tobacco, potato, citrus, corn etc..Nematode typically result in crop failure 10%~
40%, 80% underproduction, or even total crop failure can be caused when serious.
It is reply root knot by the cultural control method and chemical pesticide control method with non-host crop crop rotation or rice field-upland field rotation
The two big approach of nematode and cyst nematode harm.The high toxicants such as phonamiphos, carbofuran, terbufos with chemical pesticide
It limits or is forbidden to use, avermectin becomes the anti-medicament of master of current nematode, but due to long-term single use, nematode is to it
Generate larger resistance.Therefore, it is badly in need of a kind of high-efficiency low-toxicity control of nematode medicament to break away from the single situation of current medicament.
Fosthiazate, chemical name：O- ethyl-S- sec-butyl -2- oxo -1,3- thiazolidine -3- base Thiophosphonates, have
Tag and systemic action, the root-knot nematode for killing and having invaded crop root and having formed root nodule can be absorbed by plant roots.Fosthiazate toxicity
It is relatively low, meet export of farm produce standard, is mainly used for preventing nematode, aphid etc., to root-knot nematode, pratylenchus, cyst nematode
There is special efficacy.
Trichoderma harzianum is the microbial bactericide produced by Bai Wo limited liability companies of the U.S., is mainly used for prevention and plants
The fungal disease of object root.Trichoderma harzianum can not only effectively inhibit the growth of germ, and can generate stimulation plant growth and
The compound for inducing plant defense response, improves the microenvironment of root system, enhances the growing way and disease resistance of plant, improve crop
Yield and income.Trichoderma harzianum, which is applied to prevention root-knot nematode, relevant report, as Ma Jinhui, Zhu Pingping are delivered
《The identification of trichoderma harzianum strain TRI2 and its preventive and therapeutic effect to cucumber root-knot nematode》It points out, Trichoderma TRI2 zymotic fluids exist
Root-knot nematode can be killed with 100% when 48h, so that cucumber root knot decline rate is reached 63.5% in pot experiment, in field to Huang
The control effect of melon root-knot nematode reaches 72.2%, and has similar control effect in field and avermectin.
Currently, using fosthiazate, trichoderma harzianum, as the granular formulation for killing nematode of active ingredient, there are no relevant reports.
Invention content
The object of the present invention is to provide a kind of granular formulation for killing nematode containing fosthiazate, have high-efficiency low-toxicity, can significantly carry
High root-knot nematode, cyst nematode preventive effect, reduce pesticide mu input cost the advantages of.
The technical solution used in the present invention is:A kind of granular formulation for killing nematode containing fosthiazate, active constituent is by fosthiazate
It is formed with trichoderma harzianum.
The active constituent, trichoderma harzianum are set to 100% female medicine with 30,000,000,000 CFU/ grams of female medicines, fosthiazate with breathe out
The weight ratio of thatch Trichoderma is 5-90:1, the content of fosthiazate in the composition is 2.5%~15%, and trichoderma harzianum is combining
Content in object is 0.3 hundred million CFU/ grams~1.5 hundred million CFU/ grams.
The adjuvant that the granular formulation for killing nematode containing fosthiazate uses includes filler, binder, dispersant, wetting
Agent, disintegrant, sustained release agent, stabilizer or it is other be beneficial to active constituent in the formulation stablize and drug effect play substance, be all
The various composition used is commonly used or allowed in agriculture field preparation.
The present invention has the following advantages and significant technique effect:
(1) medicament high-efficiency low-toxicity compares carbofuran, and medicament is substantially reduced the toxicity of people and animals, avoids production and application
The risk of process person poultry poisoning.
(2) active constituent fosthiazate and trichoderma harzianum are synergistic, use in the reasonable scope, can reduce each single dose
Amount of application advantageously reduces drug cost and reduces environmental pollution.
(3) trichoderma harzianum can improve the microenvironment of soil, keep plant root growth healthier, to the root in soil-borne disease
Maize ear rot, southern blight, samping off, damping-off have preferable control effect.
Specific implementation mode
Technical scheme of the present invention and technique effect are described further below by way of specific embodiment, institute of the present invention
The percentage stated is weight percentage.
One, indoor joint toxicity measuring test
The indoor joint toxicity measuring test of fosthiazate, trichoderma harzianum and its mixed agent, with fosthiazate, trichoderma harzianum
And its mixed agent dilutes 5 concentration by active constituent content gradient series, is compared with sterile water, tests with Meloidogyne incognita
Second instar larvae is test worm, and blank control is arranged, and fosthiazate, trichoderma harzianum single dose and its mixture preparation are used dip method, into
Row toxicity test simultaneously does statistical analysis.
The synergistic effect of pharmacy mix is evaluated with the co-toxicity coefficient method (CTC) of Sun Yunpei's Method, i.e., CTC≤80 are that antagonism is made
With 80<CTC<120 be summation action, and CTC >=120 are synergistic effect.Statistical result is as shown in table 1：
The Toxicity Determination table of 1 fosthiazate of table, trichoderma harzianum and its mixed agent to cucumber root-knot nematode
The measurement result of indoor joint toxicity measuring test shows that the mixed ratio of fosthiazate and trichoderma harzianum is 2:1
When, co-toxicity coefficient (CTC) is 110.6, and the two mixture is summation action；The mixed ratio of fosthiazate and trichoderma harzianum is 1:5
When, co-toxicity coefficient (CTC) is less than 80, and the two mixture is antagonism；The mixed ratio of fosthiazate and trichoderma harzianum is 5-90:
When 1 range, co-toxicity coefficient (CTC) is all higher than 120, i.e. synergistic effect is apparent.
Two, product embodiments
Embodiment 1：2.5% fosthiazate, 0.3 hundred million cfu/ grams of trichoderma harzianum granule
Formula：It is 25 according to the weight ratio of fosthiazate and trichoderma harzianum:1,95% fosthiazate active compound 2.63kg is weighed,
30000000000 cfu/ grams of Trichoderma harzianum starter medicine 0.1kg, fatty alcohol polyoxyethylene ether 2.0kg, lauryl sodium sulfate 2.5kg, poly- second
Enol 1.5kg, carboxymethyl cellulose 2.5kg, kaolin complement to 100kg.
Embodiment 2：5.0% fosthiazate, 0.5 hundred million cfu/ grams of trichoderma harzianum granule
Formula：It is 30 according to the weight ratio of fosthiazate and trichoderma harzianum:1,95% fosthiazate active compound 5.26kg is weighed,
30000000000 cfu/ grams of Trichoderma harzianum starter medicine 0.17kg, naphthalenesulfonate formaldehyde condensation compound 2.5kg, lauryl sodium sulfate 1.5kg,
Polyvinyl alcohol 2.5kg, attapulgite 5kg, bentonite complement to 100kg.
Embodiment 3：10.0% fosthiazate, 0.5 hundred million cfu/ grams of trichoderma harzianum granule
Formula：It is 60 according to the weight ratio of fosthiazate and trichoderma harzianum:1,95% fosthiazate active compound 5.26kg is weighed,
30000000000 cfu/ grams of Trichoderma harzianum starter medicine 0.17kg, carboxymethyl cellulose 2.5kg, lauryl sodium sulfate 2.5kg, polyethylene
Alcohol 1.5kg, attapulgite 15kg, kaolin complement to 100kg.
Embodiment 4：10.0% fosthiazate, 1.5 hundred million cfu/ grams of trichoderma harzianum granule
Formula：It is 20 according to the weight ratio of fosthiazate and trichoderma harzianum:1,95% fosthiazate active compound 10.53kg is weighed,
30000000000 cfu/ grams of Trichoderma harzianum starter medicine 0.5kg, naphthalenesulfonate formaldehyde condensation compound 3.5kg, lauryl sodium sulfate 2.5kg gather
Ethylene glycol 2.0kg, bentonite supply 100kg.
Embodiment 5：15.0% fosthiazate, 1.0 hundred million cfu/ grams of trichoderma harzianum granule
Formula：It is 45 according to the weight ratio of fosthiazate and trichoderma harzianum:1,95% fosthiazate active compound 15.79kg is weighed,
30000000000 cfu/ grams of Trichoderma harzianum starter medicine 0.33kg, lauryl sodium sulfate 2.5kg, carboxymethyl cellulose 1.5kg, diatomite
15kg, bentonite supply 100kg.
Preparation method：Recipe ingredient described in above-described embodiment 1-5 is uniformly mixed, crushes, fully stirs after wetting with water
It mixes uniformly, then is granulated with screw extruder pelletizer, is sieved after dry up to being fosthiazate and trichoderma harzianum containing active constituent
Granule.
Three, products application embodiment
Embodiment 1 to 5 products obtained therefrom of embodiment is carried out to the prevention of cucumber root-knot nematode, test process setting is as follows：
Processing 1：2.5% fosthiazate, 0.3 hundred million cfu/ grams of trichoderma harzianum granule, amount of application are 30kg/ mus.
Processing 2：5.0% fosthiazate, 0.5 hundred million cfu/ grams of trichoderma harzianum granule, amount of application are 15kg/ mus..
Processing 3：10.0% fosthiazate, 0.5 hundred million cfu/ grams of trichoderma harzianum granule, amount of application are 8kg/ mus.
Processing 4：10.0% fosthiazate, 1.5 hundred million cfu/ grams of trichoderma harzianum granule, amount of application are 8kg/ mus.
Processing 5：15.0% fosthiazate, 1.0 hundred million cfu/ grams of trichoderma harzianum granule, amount of application are 5kg/ mus.
Processing 6：10.0% fosthiazate granule, amount of application are 15kg/ mus.
Processing 7：5.0 hundred million cfu/ grams of trichoderma harzianum granules, amount of application are 45kg/ mus.
Processing 8：Blank control.
Above-mentioned processing is applied in cucumber vegetative growth phase, 30 days after medicine, is carried out within 50 days root-knot nematode respectively and is caused harm investigation, receipts
Determination of yield is carried out when obtaining, final statistical result is as shown in the table：
Claims (2)
1. a kind of granular formulation for killing nematode containing fosthiazate, which is characterized in that active constituent is made of fosthiazate and trichoderma harzianum,
The trichoderma harzianum is set to 100% female medicine with 30,000,000,000 CFU/ grams of female medicines, and the weight ratio of fosthiazate and trichoderma harzianum is
5-90:1。
2. the granular formulation for killing nematode according to claim 1 containing fosthiazate, which is characterized in that fosthiazate is in granule
Weight percent is 2.5%~15%, and content of the trichoderma harzianum in granule is 0.3 hundred million CFU/ grams~1.5 hundred million CFU/ grams.
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| CN105454298B (en) * | 2016-01-19 | 2018-04-17 | 陕西康禾立丰生物科技药业有限公司 | A kind of composition pesticide for preventing nematodiasis |
| CN105660711B (en) * | 2016-04-01 | 2018-08-07 | 青岛正道药业有限公司 | A kind of nematode granule with slow seedling effect |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN102669184A (en) * | 2012-01-15 | 2012-09-19 | 河南科技大学 | Preparation for reducing meloidogyne and preparation method thereof |
| CN104522049A (en) * | 2014-12-30 | 2015-04-22 | 海利尔药业集团股份有限公司 | Nematicidal composition containing fluensulfone and fosthiazate |
| JP2015166386A (en) * | 2015-06-05 | 2015-09-24 | 住友化学株式会社 | Pest control method in soybean |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102669184A (en) * | 2012-01-15 | 2012-09-19 | 河南科技大学 | Preparation for reducing meloidogyne and preparation method thereof |
| CN104522049A (en) * | 2014-12-30 | 2015-04-22 | 海利尔药业集团股份有限公司 | Nematicidal composition containing fluensulfone and fosthiazate |
| JP2015166386A (en) * | 2015-06-05 | 2015-09-24 | 住友化学株式会社 | Pest control method in soybean |
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| 10%噻唑磷颗粒剂防治黄瓜根结线虫;朱金文等;《植物保护》;20040630;第30卷(第3期);第82-83页 * |
| 哈茨木霉菌株TRI2 的鉴定及其对黄瓜根结线虫的防治作用;马金慧等;《中国农学通报》;20140831;第30卷(第22期);第263-269页 * |
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Effective date of registration: 20180816 Address after: 322100 Zhejiang, Jinhua, Dongyang, Jiangbei street, 1 New Village Applicant after: New Mstar Technology Ltd in Dongyang Address before: 530000 room 3106, block C, hang Yang International City, No. 131, National Road, Qingxiu District, Nanning, the Guangxi Zhuang Autonomous Region. Applicant before: GUANGXI NANNING YITU BIOTECHNOLOGY CO., LTD. |
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Effective date of registration: 20220424 Address after: 061000 room 515, national circular economy promotion center, Cangzhou Lingang Economic and Technological Development Zone, Cangzhou City, Hebei Province Patentee after: HEBEI SAIFENG BIOTECHNOLOGY CO.,LTD. Address before: 322100 Zhejiang, Jinhua, Dongyang, Jiangbei street, 1 New Village Patentee before: DONGYANG TEYI NEW MATERIAL TECHNOLOGY Co.,Ltd. |
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