CN105145599A - Bactericide containing thifluzamide and cinnamyl aldehyde - Google Patents
Bactericide containing thifluzamide and cinnamyl aldehyde Download PDFInfo
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- CN105145599A CN105145599A CN201510697709.6A CN201510697709A CN105145599A CN 105145599 A CN105145599 A CN 105145599A CN 201510697709 A CN201510697709 A CN 201510697709A CN 105145599 A CN105145599 A CN 105145599A
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- bactericide
- thifluzamide
- cinnamic acid
- cinnamyl aldehyde
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Abstract
The invention relates to a bactericide containing thifluzamide and cinnamyl aldehyde. Active components include thifluzamide and cinnamyl aldehyde, and the weight ratio of thifluzamide to cinnamyl aldehyde is 1-5 to 1. It is required to protect the application of the bactericide in prevention and treatment of rice sheath blight disease. Traditional Chinese medicine cinnamyl aldehyde and bactericide components are mixed; it is proved through tests that after cinnamyl aldehyde is added to the bactericide components, the drug resistance of pathogen to the bactericide can be reversed; thus, the prevention and treatment effect of the bactericide is improved, bactericide cost and bactericide residuals can be greatly reduced, more economic benefits are created for farmers, and meanwhile food safety is ensured.
Description
Technical field
The present invention relates to technical field of pesticide, specifically a kind of bactericide containing thifluzamide and cinnamic acid.
Background technology
Cinnamic acid is cinnamon spirit main body of oil, and another name is called beautiful osmanthus, is the kind that Lauraceae Chinese cassia tree belongs to.Cinnamic acid is also called cinnaldehydrum, has very strong aromatic odor, and pure cinnamic acid is colourless or faint yellow vigorous thick liquid, and easily oxidized in atmosphere, naturally occurring cinnamic acid mostly is transconfiguration, is present in the plant corpuss such as Chinese cassia tree in a large number.
At present, the research of cinnamyl alcohol is limited to the application of food industry applications and medical industry more, such as, research finds, the mould, aspergillus, Mucor, head mold, the bud branch that obtain are mould, sickle-like bacteria carries out antibacterial activity test to being separated in food to utilize cinnamic acid, minimal inhibitory concentration can reach 6mg/kg, and anti-mold effect is good; Utilize cinnamic acid missible oil to test the fresh-keeping of mango, result shows more remarkable than the control efficiency of conventional sterilants; Suppress the mechanism of aspergillus flavus to be studied to cinnamic acid, think that first cinnamic acid damages its cell membrane, and then change intracellular space structure, as protein, nucleic acid etc.Also own through showing that cinnamic acid all has significant bactericidal action to Escherichia coli, staphylococcus aureus, salmonella, hay bacillus, proteus etc. in medical industry.But, do not retrieve the relevant report being applied to the water prevention rice sheath blight at present.
Thifluzamide, Chinese another name: thifluzamide; The bromo-2-methyl of 2', 6'-bis--4'-trifluoromethoxy-4-Trifluoromethyl-1,3-thiadiazoles-5-hydroxyl anilide; Thiophene fluorine bacterium amine; Thifluzamide/bromo-2-the methyl of 2', 6'-bis--4'-trifluoromethoxy-4-Trifluoromethyl-1,3-thiadiazoles-5-hydroxyl anilide.Thifluzamide is succinate dehydrogenase inhibitor, suppresses succinic acid dehydrogenase in germ tricarbonic acid cycle, causes thalline dead.It has very strong Uptake and translocation performance, can the mode such as foliar spray, seed treatment, soil treatment use.Thifluzamide all has good control efficiency to many kinds of fungal diseases, can be widely used in the various crop such as water paddy and wheat class, peanut, cotton, beet, coffee, potato, lawn.Production is mainly used in the banded sclerotial blight of preventing and treating paddy rice and wheat class.In recent years due to its large-area popularization, pathogen is caused to reduce its susceptibility, resistance grow.
Summary of the invention
The technical problem to be solved in the present invention is, for the deficiency that above-mentioned existing bactericide exists, a kind of bactericide containing thifluzamide and cinnamic acid is provided, overcome that existing bactericide causes due to resistance problems preventive effect reduces, consumption strengthens, residual high and defect that cost is high.
The present invention realizes the technical scheme that above-mentioned purpose takes: a kind of bactericide containing thifluzamide and cinnamic acid, active ingredient is made up of thifluzamide and cinnamic acid, and described cinnamic acid and the weight ratio of thifluzamide are 1-5:1.
The present invention's also application of claimed described bactericide on the water prevention rice sheath blight.
The present invention utilizes Chinese traditional medicine cinnamon aldehyde and microbiocidal composition mixture, test proves, add cinnamic acid in germicide constituent after, the pesticide resistance of pathogen to bactericide can be reversed, thus improve the control efficiency of bactericide, and can significantly reduce drug cost and medicament residue, for peasant household creates higher economic benefit, also ensure that food security simultaneously.
Embodiment
Below in conjunction with test data and embodiment, technical scheme of the present invention and beneficial effect are described further.
One indoor joint toxicity measuring test
For clear and definite bactericide (propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu, Difenoconazole) and cinnamic acid mixture affect the virulence of Rhizoctonia solani Kuhn, mycelial growth rate method is adopted to carry out indoor measurement.
Rhizoctonia solani Kuhn is separated from surrounding area, Guigang, purifying cultivate after through Koch's Postulates verify its pathogenic after by strain inoculation in PDA medium, at 25 DEG C, under 90% damp condition, cultivate 5d, break into bacterium cake with 0.4cm card punch after mycelia covers with culture dish and use.
Cinnamic acid and bactericide are pressed active ingredient part by weight 1:1 respectively, 2:1, 5:1, 10:1 mixing is made into binary built agent as mixture 1-mixture 4, bactericide single dose and mixture 1-mixture 4 are respectively diluted 6 concentration according to geometric ratio gradient from 10ppm, blank is made with clear water process, make PDA flat board, arranging without medicament is contrast, every concentration repeats 3 times, after aseptically the bacterium cake accomplished fluently being inverted in the dull and stereotyped central authorities of each process PDA, flat board is placed in 25 DEG C, cultivate under 90% damp condition, investigation result when mycelial growth diameter reaches culture dish diameter about 50%, calculate inhibiting rate, and the EC of each chemicals treatment is calculated by DPS Software of Data Statistics
50and composite co-toxicity coefficient.Because cinnamic acid single dose does not almost affect for Rhizoctonia solani Kuhn, therefore the present invention calculate composite co-toxicity coefficient time by the EC of cinnamic acid single dose
50be designated as 0, the EC of co-toxicity coefficient=composite
50the EC of/bactericide single dose
50.Statistics is as shown in the table.
As can be known from the above table: cinnamic acid and propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu all has obvious synergistic effect to Rhizoctonia solani Kuhn afterwards in 1-5:1 ratio is composite, and cinnamic acid and propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu shows inhibitory action to Rhizoctonia solani Kuhn afterwards in 10:1 ratio is composite, and cinnamic acid and Difenoconazole are added or inhibitory action in composite rear to show Rhizoctonia solani Kuhn of 1-10:1 ratio.
Two field medicine effect tests
Test medicine
12 single doses: propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu, Difenoconazole;
12 mixed agents: be the weight ratio of 2:1 according to cinnamic acid and bactericide, add cinnamic acid in above-mentioned single dose.
Test establishes 25 process altogether together with blank, and each process repeats for 3 times, 75 communities, each community randomized arrangement.
Test method
By above-mentioned single dose and mixed agent even spraying, the effective ingredient consumption conveniently consumption use of bactericide single dose, the microbiocidal composition consumption in mixture and single dose are together.21 days investigation rice sheath blight disease controlling results after medicine.
Result of the test
As can be known from the above table: cinnamic acid and propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol well, ridge mycin are more obvious than single dose good in the composite rear preventive effect to rice sheath blight disease of 2:1 ratio, and cinnamic acid and Difenoconazole are more or less the same in the composite rear preventive effect to rice sheath blight disease of 2:1 ratio and single dose.
Claims (2)
1. contain a bactericide for thifluzamide and cinnamic acid, it is characterized in that, active ingredient is made up of thifluzamide and cinnamic acid, and described cinnamic acid and the weight ratio of thifluzamide are 1-5:1.
2. the application of bactericide according to claim 1 on the water prevention rice sheath blight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510697709.6A CN105145599A (en) | 2015-10-26 | 2015-10-26 | Bactericide containing thifluzamide and cinnamyl aldehyde |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510697709.6A CN105145599A (en) | 2015-10-26 | 2015-10-26 | Bactericide containing thifluzamide and cinnamyl aldehyde |
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| CN105145599A true CN105145599A (en) | 2015-12-16 |
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| CN201510697709.6A Pending CN105145599A (en) | 2015-10-26 | 2015-10-26 | Bactericide containing thifluzamide and cinnamyl aldehyde |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106614668A (en) * | 2016-12-16 | 2017-05-10 | 张宗斌 | Sterilization composition containing thifluzamide and cinnamic acid |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102388872A (en) * | 2011-11-30 | 2012-03-28 | 江苏省农业科学院 | Bactericide for promoting growth and controlling rice sheath blight and application thereof |
| WO2014078849A1 (en) * | 2012-11-19 | 2014-05-22 | Lonza, Inc. | Succinate dehydrogenase inhibitor containing compositions |
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2015
- 2015-10-26 CN CN201510697709.6A patent/CN105145599A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102388872A (en) * | 2011-11-30 | 2012-03-28 | 江苏省农业科学院 | Bactericide for promoting growth and controlling rice sheath blight and application thereof |
| WO2014078849A1 (en) * | 2012-11-19 | 2014-05-22 | Lonza, Inc. | Succinate dehydrogenase inhibitor containing compositions |
Non-Patent Citations (1)
| Title |
|---|
| 袁会珠: "《现代农药应用技术图解》", 30 June 2013 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106614668A (en) * | 2016-12-16 | 2017-05-10 | 张宗斌 | Sterilization composition containing thifluzamide and cinnamic acid |
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Application publication date: 20151216 |