CN105115955A - Optical fiber detection device for biological detection - Google Patents
Optical fiber detection device for biological detection Download PDFInfo
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- CN105115955A CN105115955A CN201510591354.2A CN201510591354A CN105115955A CN 105115955 A CN105115955 A CN 105115955A CN 201510591354 A CN201510591354 A CN 201510591354A CN 105115955 A CN105115955 A CN 105115955A
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Abstract
The invention relates to an optical fiber detection device for biological detection. The optical fiber detection device comprises an optical fiber probe, an optical fiber bundle assembly, a laser device and a fluorescence collection photoelectric receiver, wherein the optical fiber probe and the optical fiber bundle assembly are connected with each other, and the laser device and the fluorescence collection photoelectric receiver are connected with the optical fiber bundle assembly. The optical fiber bundle assembly is a Y-type optical fiber bundle assembly which comprises an overall optical fiber bundle end, a single-mode optical fiber and branch optical fibers, wherein the single-mode optical fiber and the branch optical fibers are connected with the overall optical fiber bundle end. The optical fiber detection device has the advantages that by the adoption of the optical fiber probe and the Y-type optical fiber bundle assembly, transmission of laser beams and collection and transmission of optical signals are completed; by connecting the single-mode optical fiber to the LD laser device, it is guaranteed that the mode of laser beams collected by the single-mode optical fiber is singular; through the conical optical fiber probe, the collection quantity of fluorescence signals is guaranteed; through the branch optical fibers of the Y-type optical fiber bundle assembly and the fluorescence collection photoelectric receiver, the coupling efficiency of optical signals is improved, the signal-to-noise ratio of the equipment is reduced, the structure of the equipment is simplified, and the cost is lowered.
Description
Technical field
The present invention relates to technical field of biological, particularly utilize laser excitation to be marked with the biological substance luminescence of fluorescence molecule, thus realize the technology of biological detection, be specifically related to a kind of fiber optic detector for biological detection.
Background technology
Optical fiber is fibre-optic abbreviation.It is the soft filament pulled into quartz glass or tailormadepiston, and its structure is fibre core, covering and coat from inside to outside.The refractive index of covering is slightly less than the refractive index of fibre core, and by the total reflection principle of geometrical optics, light is bound in fibre core and transmits.At the coat that the outside of covering is 5-40 μm, its effect is the physical strength strengthening optical fiber, increases pliability simultaneously.Outermost sets up 100 μm of thick cushions or layer moulded by cover.
The feature development such as Fibre Optical Sensor is not subject to electromagnetic interference (EMI) owing to having, volume is little, highly sensitive, speed is fast, easy to operate are very fast; Fiber-optic probe device is the critical component of Fibre Optical Sensor, is widely applied in food inspection, environment measuring, medical research etc.Traditional optical fiber biosensor utilizes optical fiber as probe and optical transmission of information, but still utilizes optical fractionation components and parts when information, therefore, system complex, volume is large; New Fibre Optical Sensor has been had to instead of traditional Fibre Optical Sensor at present, fiber-optic probe device in this novel optical fiber sensor adopts conical fiber and list-multi-module optical fiber coupler to combine, because this list-multi-module optical fiber coupler is that employing single-mode fiber and a root multimode fiber fused biconical taper are made, single-mode fiber and multimode optical fiber sectional area difference hundreds of times, so the manufacture craft difficulty of coupling mechanism is very large, yield rate is very low, cost is very high, is unfavorable for product mass production and marketing.
Summary of the invention
In order to overcome defect of the prior art, the invention provides a kind of fiber optic detector for biological detection.
The present invention is achieved through the following technical solutions:
A kind of fiber optic detector for biological detection, comprise interconnective fibre-optical probe and fibre bundle assembly, be connected with described fibre bundle assembly, for the laser instrument of Emission Lasers bundle, and be connected with described fibre bundle assembly, for receiving the fluorescent collecting photelectric receiver of photosignal; Described fibre bundle assembly is Y shape optical fiber beam assembly, and described Y shape optical fiber beam assembly comprises fibre bundle and always holds and always hold the single-mode fiber, the branch optical fiber that are connected respectively with fibre bundle; Wherein,
The described laser instrument laser beam of launching is through the Single-Mode Fiber Coupling of Y shape optical fiber beam assembly to fibre-optical probe, and described fibre-optical probe carries biological identification molecule after treatment, and inserts in material to be detected, for collecting fluorescence signal by the fibre-optical probe after processing; The fluorescence signal that described fibre-optical probe is collected transfers to fluorescent collecting photelectric receiver through the branch optical fiber of Y shape optical fiber beam assembly.
Described technical scheme is preferably, and described fibre-optical probe comprises probe body and is arranged at first end body and the second end body at probe body two ends respectively.
Described technical scheme is preferably, and described probe body is tapered.
Described technical scheme is preferably, and described laser instrument is LD laser instrument.
Described technical scheme is preferably, and described single-mode fiber is set to one.
Described technical scheme is preferably, and described branch optical fiber comprises some multimode optical fibers.
Described technical scheme is preferably, described multimode optical fiber circular array.
Described technical scheme is preferably, and described fiber optic detector is provided with the housing for receiving optical fiber sniffer, and described housing is provided with vacuum pump.Fiber optic detector is put into housing after finishing using by described fiber optic detector, is taken away by the air in housing by vacuum pump, makes fiber optic detector be in a closed vacuum environment, utilizes and store.
Compared with prior art, superior effect of the present invention is: adopt fibre-optical probe and Y shape optical fiber beam assembly, completes the collection of the transmission of laser beam and light signal, transmission; Connect LD laser instrument by single-mode fiber, the laser beam pattern that bonding mode fiber gathers is single; The collecting amount of fluorescence signal is ensured by the fibre-optical probe of taper, and pass through branch optical fiber and the fluorescent collecting photelectric receiver of Y shape optical fiber beam assembly, improve the coupling efficiency of light signal, reduce the signal to noise ratio (S/N ratio) of equipment simultaneously, simplify the structure of equipment, reduce cost.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of fiber optic detector for biological detection of the present invention.
Reference numeral is as follows:
1-fibre-optical probe, 11-probe body, 12-first end body, 13-second end body, 2-fibre bundle assembly, 21-fibre bundle are always held, 22-single-mode fiber, 23-branch optical fiber, 3-laser instrument, 4-fluorescent collecting photelectric receiver.
Embodiment
Below in conjunction with accompanying drawing, the specific embodiment of the invention is described in further detail.
As shown in Figure 1, a kind of fiber optic detector for biological detection of the present invention, comprise interconnective fibre-optical probe 1 and fibre bundle assembly 2, be connected with described fibre bundle assembly 2, for the laser instrument 3 of Emission Lasers bundle, that be connected with described fibre bundle assembly 2 and for receiving photosignal fluorescent collecting photelectric receiver 4.Described fibre bundle assembly 2 is Y shape optical fiber beam assembly, and described Y shape optical fiber beam assembly comprises fibre bundle and always holds 21 and always hold 21 single-mode fibers be connected 22, branch optical fiber 23 with fibre bundle respectively; Wherein, the laser beam that described laser instrument 3 is launched is coupled to fibre-optical probe 1 through the single-mode fiber 22 of Y shape optical fiber beam assembly, described fibre-optical probe 1 carries biological identification molecule after treatment, and inserts in material to be detected, for collecting fluorescence signal by the fibre-optical probe 1 after process; The fluorescence signal that described fibre-optical probe 1 is collected transfers to fluorescent collecting photelectric receiver 4 through the branch optical fiber 23 of Y shape optical fiber beam assembly.Further, described single-mode fiber 22, the outside of branch optical fiber 23 are provided with clad 24.
In the above-described embodiments, described fibre-optical probe 1 comprises probe body 11 and is arranged at first end body 12 and the second end body 13 at probe body 11 two ends respectively, and described probe body 11 is tapered.Described laser instrument 3 is LD laser instrument.Described single-mode fiber 22 is set to one, and described branch optical fiber 23 comprises some multimode optical fibers, and further, described multimode optical fiber is set to the six roots of sensation; Described multimode optical fiber circular array, and be arranged at the outside of single-mode fiber 22.
In the specific implementation, the laser beam that described laser instrument 3 is launched is coupled to the single-mode fiber 22 of fibre bundle assembly 2, because the quantity of described single-mode fiber 22 is set to one, the laser beam that the cutoff wavelength of described single-mode fiber 22 and laser instrument 3 send Wavelength matched, the laser beam that laser instrument 3 is launched is coupled to fibre-optical probe 1 through single-mode fiber 22, further, the fibre bundle of described fibre bundle assembly 2 always holds 21 to be connected with the second end body 13 of fibre-optical probe 1, the first end body 12 of fibre-optical probe 1 applies biological identification molecule, first end body 12 is made to carry biological identification molecule, the first end body 12 of fibre-optical probe 1 is inserted in material to be detected, laser beam excites biological identification molecule to send fluorescence at fibre-optical probe 1 place, described first end body 12 is for collecting fluorescence signal, the fluorescence signal collected is through the first end body 12 of fibre-optical probe 1, probe body 11 and the second end body 13, described second end body 13 always holds 21 to be connected with fibre bundle, and then always hold 21 to enter fibre bundle assembly 2 through fibre bundle, and transfer to fluorescent collecting photelectric receiver 4 by branch optical fiber 23, improve coupling efficiency and the transfer efficiency of light signal.
The present invention is not limited to above-mentioned embodiment, and when not deviating from flesh and blood of the present invention, any distortion that it may occur to persons skilled in the art that, improvement, replacement all fall into protection scope of the present invention.
Claims (7)
1. the fiber optic detector for biological detection, it is characterized in that, comprise interconnective fibre-optical probe and fibre bundle assembly, be connected with described fibre bundle assembly, for the laser instrument of Emission Lasers bundle, and be connected with described fibre bundle assembly, for receiving the fluorescent collecting photelectric receiver of photosignal; Described fibre bundle assembly is Y shape optical fiber beam assembly, and described Y shape optical fiber beam assembly comprises fibre bundle and always holds and always hold the single-mode fiber, the branch optical fiber that are connected respectively with fibre bundle; Wherein,
The described laser instrument laser beam of launching is through the Single-Mode Fiber Coupling of Y shape optical fiber beam assembly to fibre-optical probe, and described fibre-optical probe carries biological identification molecule after treatment, and inserts in material to be detected, for collecting fluorescence signal by the fibre-optical probe after processing; The fluorescence signal that described fibre-optical probe is collected transfers to fluorescent collecting photelectric receiver through the branch optical fiber of Y shape optical fiber beam assembly.
2. a kind of fiber optic detector for biological detection according to claim 1, is characterized in that, described fibre-optical probe comprises probe body and is arranged at first end body and the second end body at probe body two ends respectively.
3. a kind of fiber optic detector for biological detection according to claim 2, it is characterized in that, described probe body is tapered.
4. a kind of fiber optic detector for biological detection according to claim 1, is characterized in that, described laser instrument is LD laser instrument.
5. a kind of fiber optic detector for biological detection according to claim 1, it is characterized in that, described single-mode fiber is set to one.
6. a kind of fiber optic detector for biological detection according to claim 1, it is characterized in that, described branch optical fiber comprises some multimode optical fibers.
7. a kind of fiber optic detector for biological detection according to claim 6, is characterized in that, described multimode optical fiber circular array.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201510591354.2A CN105115955A (en) | 2015-09-16 | 2015-09-16 | Optical fiber detection device for biological detection |
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| CN201510591354.2A CN105115955A (en) | 2015-09-16 | 2015-09-16 | Optical fiber detection device for biological detection |
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| CN105115955A true CN105115955A (en) | 2015-12-02 |
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| CN201510591354.2A Pending CN105115955A (en) | 2015-09-16 | 2015-09-16 | Optical fiber detection device for biological detection |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105606583A (en) * | 2016-03-25 | 2016-05-25 | 北京首量科技有限公司 | Optical fiber detection system for biological detection |
| CN105759372A (en) * | 2016-04-27 | 2016-07-13 | 武汉电信器件有限公司 | Optic lens assembly and method thereof |
| CN106404669A (en) * | 2016-11-01 | 2017-02-15 | 北京华泰诺安技术有限公司 | Remote laser spectrum detection apparatus and remote laser spectrum detection method |
| CN107300538A (en) * | 2017-08-28 | 2017-10-27 | 重庆三峡医药高等专科学校 | A kind of unicellular accurate test experience device based on optical fiber |
| CN109143121A (en) * | 2018-08-13 | 2019-01-04 | 南京邮电大学 | One kind being based on pulse modulated microwave field quantitative testing system and method |
| CN111413306A (en) * | 2020-04-07 | 2020-07-14 | 光越科技(深圳)有限公司 | Fluorescence detector, detection array and method for manufacturing fluorescence detector |
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| US4573761A (en) * | 1983-09-14 | 1986-03-04 | The Dow Chemical Company | Fiber-optic probe for sensitive Raman analysis |
| US6229940B1 (en) * | 1998-11-30 | 2001-05-08 | Mcdonnell Douglas Corporation | Incoherent fiber optic laser system |
| JP2002202439A (en) * | 2000-12-27 | 2002-07-19 | Kyocera Corp | Optical waveguide body, optical waveguide device having it and optical module |
| JP2004029478A (en) * | 2002-06-26 | 2004-01-29 | Kyocera Corp | Fiber type optical device |
| CN1873450A (en) * | 2006-06-30 | 2006-12-06 | 清华大学 | Biosensor of full fiber optic evanescent wave |
| JP2011085840A (en) * | 2009-10-19 | 2011-04-28 | Nikon Corp | Illuminating device for microscope |
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2015
- 2015-09-16 CN CN201510591354.2A patent/CN105115955A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US4573761A (en) * | 1983-09-14 | 1986-03-04 | The Dow Chemical Company | Fiber-optic probe for sensitive Raman analysis |
| US6229940B1 (en) * | 1998-11-30 | 2001-05-08 | Mcdonnell Douglas Corporation | Incoherent fiber optic laser system |
| JP2002202439A (en) * | 2000-12-27 | 2002-07-19 | Kyocera Corp | Optical waveguide body, optical waveguide device having it and optical module |
| JP2004029478A (en) * | 2002-06-26 | 2004-01-29 | Kyocera Corp | Fiber type optical device |
| CN1873450A (en) * | 2006-06-30 | 2006-12-06 | 清华大学 | Biosensor of full fiber optic evanescent wave |
| JP2011085840A (en) * | 2009-10-19 | 2011-04-28 | Nikon Corp | Illuminating device for microscope |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105606583A (en) * | 2016-03-25 | 2016-05-25 | 北京首量科技有限公司 | Optical fiber detection system for biological detection |
| CN105759372A (en) * | 2016-04-27 | 2016-07-13 | 武汉电信器件有限公司 | Optic lens assembly and method thereof |
| CN105759372B (en) * | 2016-04-27 | 2018-05-22 | 武汉电信器件有限公司 | A kind of optical lens component and its method |
| CN106404669A (en) * | 2016-11-01 | 2017-02-15 | 北京华泰诺安技术有限公司 | Remote laser spectrum detection apparatus and remote laser spectrum detection method |
| CN107300538A (en) * | 2017-08-28 | 2017-10-27 | 重庆三峡医药高等专科学校 | A kind of unicellular accurate test experience device based on optical fiber |
| CN109143121A (en) * | 2018-08-13 | 2019-01-04 | 南京邮电大学 | One kind being based on pulse modulated microwave field quantitative testing system and method |
| CN111413306A (en) * | 2020-04-07 | 2020-07-14 | 光越科技(深圳)有限公司 | Fluorescence detector, detection array and method for manufacturing fluorescence detector |
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Address after: 101111, Beijing, Tongzhou District city channel light mechanical and electrical integration industrial base, four light street, No. 2, building 304, room 5 Applicant after: Beijing Polytron Technologies Inc Address before: 101111 Tongzhou District City, Zhongguancun science and Technology Park, Tongzhou Industrial Park, the integration of optical and electrical integration of industrial base, Xing Guang street, No. four, No. 5 Applicant before: Beijing Scitlion Technology Co., Ltd. |
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Application publication date: 20151202 |