CN105106853A - Motherwort fruit oral liquid - Google Patents

Abstract

The invention relates to motherwort fruit oral liquid and belongs to the field of Chinese materia medica preparations. The motherwort fruit oral liquid is characterized by being prepared from silkworm chrysalis, earthworms, swimming bladder, tortoise shells, marmor serpentinatum, milfoil, receptaculum nelumbinis, polygala fallax hemsl, selaginell ina, motherwort fruits, zedoary, eucommia ulmoides, herba siegesbeckiae, China roses, dutchmanspipe roots, rhodiola rosea, ferula asafetida, persimmon calyx, valeriana jatamansi, rice wine and white spirit at the degree of 60. According to the motherwort fruit oral liquid, natural animals and plants serve as raw materials, high blood pressure is treated through the combined function of various herbs, the medicine effect has a synergistic effect, drug properties are moderate, side effects on human bodies are small, the motherwort fruit oral liquid is convenient to take and remarkable in curative effect and has the functions of promoting blood circulation to remove blood stasis, regulating blood lipids, softening blood vessels and recovering the mechanism of regulating blood pressure, and it is proved through clinical verification that the effective rate of the oral liquid on treating high blood pressure reaches over 90%.

Description

A kind of Fructus Leonuri oral liquid

Technical field

The present invention relates to a kind of Fructus Leonuri oral liquid, belong to field of traditional Chinese.

Background technology

Hypertension is modal chronic disease, also be the topmost risk factor of cardiovascular and cerebrovascular disease, the blood pressure of normal person fluctuates within the specific limits with internal and external environment change, when not applying depressor, systolic pressure (high pressure) exceedes or equals 140mmHg, diastolic pressure (low pressure) exceedes or equals 90mmHg, just hypertension can be diagnosed as, hypertension is also the topmost risk factor of cardiovascular and cerebrovascular disease, apoplexy, myocardial infarction, heart failure and chronic kidney disease are its major complications, it is the principal disease of harm humans health, at present, market is treated hypertension and have Western medicine and Chinese medicine, although the effect of Western medicine treatment hypertension is rapid, but fluctuation of blood pressure is larger in pressure reduction, also large to patient's side effect, during by Chinese medicine hypertension, although toxic and side effects is little, but existing treatment by Chinese herbs effect is not very good, the effect of alleviation can only be played when treating.

Summary of the invention

In order to overcome the shortcoming that above-mentioned prior art exists, the invention provides a kind of Fructus Leonuri oral liquid, this oral liquid effectively can treat vascular hypertension, determined curative effect, and side effect is little.

Of the present invention is realize above-mentioned purpose by the following technical solutions:

A kind of Fructus Leonuri oral liquid, it is made up of the crude drug of following weight portion:

Pupa bombycis 5-10, Pheretima 20-25, Air Bladder pseudosciaenae seu Acipenser 10-15, Carapax Et Plastrum Testudinis 25-35, Ophicalcitum 5-7, achillea millefolium 15-20, Receptaculum Nelumbinis 10-20, Radix Polygalae fallacis 13-15, Herba Selaginellae 15-20, Fructus Leonuri 25-30, Rhizoma Wenyujin Concisum 20-25, the Cortex Eucommiae 15-22, Herba Siegesbeckiae 15-20, Flos Rosae Chinensis 10-15, Radix Aristolochiae 3-5, Radix Rhodiolae 20-25, Resina Ferulae 10-12, Calyx Kaki 5-8, Rhizoma valerianae latifoliae 5-8, yellow wine 25-30,60 degree of Chinese liquor 35-55.

The formula preferred weight part ratio range preparing Fructus Leonuri oral liquid of the present invention is:

Pupa bombycis 6, Pheretima 20, Air Bladder pseudosciaenae seu Acipenser 13, Carapax Et Plastrum Testudinis 35, Ophicalcitum 5, achillea millefolium 15, Receptaculum Nelumbinis 20, Radix Polygalae fallacis 13, Herba Selaginellae 20, Fructus Leonuri 25, Rhizoma Wenyujin Concisum 20, the Cortex Eucommiae 15, Herba Siegesbeckiae 20, Flos Rosae Chinensis 15, Radix Aristolochiae 3, Radix Rhodiolae 20, Resina Ferulae 12, Calyx Kaki 5, Rhizoma valerianae latifoliae 5, yellow wine 30,60 degree of Chinese liquor 40.

The formula optimum weight part ratio range preparing Fructus Leonuri oral liquid of the present invention is:

Pupa bombycis 7, Pheretima 22, Air Bladder pseudosciaenae seu Acipenser 13, Carapax Et Plastrum Testudinis 30, Ophicalcitum 6, achillea millefolium 18, Receptaculum Nelumbinis 15, Radix Polygalae fallacis 14, Herba Selaginellae 18, Fructus Leonuri 27, Rhizoma Wenyujin Concisum 23, the Cortex Eucommiae 17, Herba Siegesbeckiae 17, Flos Rosae Chinensis 12, Radix Aristolochiae 4, Radix Rhodiolae 23, Resina Ferulae 11, Calyx Kaki 6, Rhizoma valerianae latifoliae 7, yellow wine 27,60 degree of Chinese liquor 45.

Its preparation method is:

1. get achillea millefolium, Receptaculum Nelumbinis, Radix Polygalae fallacis, Herba Selaginellae, Fructus Leonuri, Rhizoma Wenyujin Concisum, the Cortex Eucommiae, Herba Siegesbeckiae, Flos Rosae Chinensis, Radix Aristolochiae, Radix Rhodiolae, Resina Ferulae, Calyx Kaki, Rhizoma valerianae latifoliae clean, clean, dry, marmite is put in chopping, adding distil water decocts twice, first time adds the water soaking 5-12 hours of crude drug 10 times amount, after intense fire is fried boiling, slow fire boiling 3 hours, gets decocting liquid, filtration again, and second time adds the distilled water of crude drug 7 times amount, decoct 1.5 hours, get twice decocting liquid to merge, filter to obtain medicinal liquid, for subsequent use;

2. Pupa bombycis, Pheretima, Air Bladder pseudosciaenae seu Acipenser are cleaned, microwave drying, with gauze parcel patent medicine bag after chopping;

3. get Ophicalcitum to pound into fragment and put into Chinese liquor and stir, sealing immersion 17-20 days also together put into by medicated bag step 2. obtained again, then by medical filtration decontamination, heat 70-90 DEG C and make medicated wine precision be 8-12 degree, cooling leaves standstill 2 hours second time and filters;

4. Carapax Et Plastrum Testudinis is cleaned and dry, smash to pieces, add yellow wine moistening, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, 200 object fine powders must be, for subsequent use;

5. medicinal liquid step 1., 3. obtained merges, temperature is concentrated into the concentrated solution of relative density 1.04-1.10 at 60-70 DEG C, after temperature leaves standstill 24 hours at 4-7 DEG C, filter to obtain clarification medicinal liquid, in its medicinal liquid, add the raw material homogenizer that 4. step obtain carry out homogenizing, sterilizing, bottled, sterilization.

In the raw material that the present invention is above-mentioned, property feature and effect of each crude drug are as follows:

Pupa bombycis: sweet in the mouth, salty, property is put down, and returns spleen, stomach warp, and parasite killing treats infantile malnutrition, promoting the production of body fluid to quench thirst;

Pheretima: salty in the mouth, cold in nature, return Liver Channel, spleen channel, urinary bladder channel, heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis;

Air Bladder pseudosciaenae seu Acipenser: sweet in the mouth, property is put down, and returns kidney channel, the kidney invigorating and essence nourishing, nourishes muscle arteries and veins, hemostasis, dissipating blood stasis, detumescence;

Carapax Et Plastrum Testudinis: salty in the mouth, sweet, cold nature, returns Liver Channel, kidney channel, heart channel, nourishing YIN for suppressing the hyperactive YANG, kidney tonifying bone strengthening, reinforcing the heart of nourishing blood;

Achillea millefolium: acrid in the mouth, bitter, property is put down, and temperature, returns lung meridian, spleen channel, urinary bladder channel, heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow;

Receptaculum Nelumbinis: bitter in the mouth, puckery, property is put down, and returns liver, spleen channel, and repercussive stops blooding;

Ophicalcitum: sour in the mouth, puckery, property is put down, and returns Liver Channel, blood circulation promoting and blood stasis dispelling, hemostasis;

Radix Polygalae fallacis: sweet in the mouth, micro-hardship, property is put down, and returns liver, kidney, spleen channel, tonify deficiency spleen invigorating, dissipating blood stasis dredging collateral;

Herba Selaginellae: acrid in the mouth, property is put down, and returns liver, heart channel, promoting blood circulation to restore menstrual flow;

Fructus Leonuri: sweet in the mouth, pungent, cold nature, returns Liver Channel, promoting blood flow to regulate menstruation, liver heat removing and eyesight improving;

Rhizoma Wenyujin Concisum: acrid in the mouth, bitter, warm in nature, return liver, spleen channel, removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia;

The Cortex Eucommiae: sweet in the mouth, micro-pungent, warm in nature, return liver, kidney channel, invigorating the liver and kidney, bone and muscle strengthening, antiabortive;

Herba Siegesbeckiae: acrid in the mouth, bitter, cold nature, returns liver, heart channel, wind-damp dispelling, the meridian dredging, removing toxic substances;

Flos Rosae Chinensis: sweet in the mouth, warm in nature, return liver, kidney channel, promoting blood flow to regulate menstruation, removing toxic substances and promoting subsidence of swelling;

Radix Aristolochiae: acrid in the mouth, bitter, cold in nature, mild toxicity, returns lung, stomach warp, promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling, suppressing the hyperactive liver blood pressure lowering;

Radix Rhodiolae: sweet in the mouth, cold in nature, puckery, return lung meridian, QI invigorating lung heat clearing, Fructus Alpiniae Oxyphyllae is nourished heart, hemostasis with astringents, dissipating blood stasis for subsidence of swelling;

Resina Ferulae: acrid in the mouth, property put down, return liver, spleen, stomach through ，ization Disorder removing food stagnancy, parasite killing, preventing the attack (or recurrence) of malaria;

Calyx Kaki: bitter in the mouth, puckery, property is put down, and returns stomach warp, lowering the adverse flow of QI;

Rhizoma valerianae latifoliae: acrid in the mouth, micro-hardship, warm in nature, GUIXIN warp, spleen channel, stomach warp, regulating the flow of Qi and the middle Jiao, dispelling cold and removing dampness, promoting blood circulation and detumescence.

Preparation specification of the present invention is bottled, every bottle of 30ml.

Usage of the present invention and consumption: oral, morning every day oral 1 time on an empty stomach, each dosage 30ml.

Beneficial effect of the present invention is:

The present invention with natural animal and plant medicine for raw material, utilize each taste medicine comprehensive function treatment hypertension, its drug effect has synergism, mild in medicine property and, little to human body side effect, and taking convenience, evident in efficacy, the present invention has blood circulation promoting and blood stasis dispelling, adjusting blood lipid, vessel softening, recover the function of the mechanism of regulation and control blood pressure, through clinical verification, the present invention treats hypertension effective percentage and reaches more than 90%.

In order to show therapeutic effect of the present invention, the present invention is by having carried out system clinical observation to 53 routine patients, and its concrete outcome is as follows:

1, physical data:

Select the routine clinical observation treatment of hyperpietic 53 made a definite diagnosis, wherein male 27 example, women 26 example, 26 ~ 76 years old age, 43 years old mean age, the shortest person of the course of disease 1 month, most elder 14 years, average 7.5 years.

2, Therapeutic Method:

Above-mentioned 53 routine hyperpietics all take oral liquid of the present invention, and every morning oral 1 time on an empty stomach, each 30ml, taking continuously 14 days is a course for the treatment of.

3, efficacy assessment standard:

Efficacy of antihypertensive treatment standard with reference to formulating in Ministry of Public Health " guideline of clinical investigations of new Chinese medicine Hypertension ":

Cure: hypertension symptom all disappears, physical recovery is normal, and body index recovers normal on inspection.

Good effect: hypertension symptom disappears substantially, body index part takes a turn for the better on inspection.

Invalid: by treating rear hypertension symptom without being clearly better.

4, therapeutic outcome:

Take oral liquid of the present invention to treat 53 routine hyperpietics, concrete efficacy result is as follows: described total effective rate=recovery from illness+effective+effectively, see the following form 1 statistics:

Curative effect	Cure	Take a turn for the better	Invalid	Untoward reaction	Total effective rate
						Total 53 examples	35 examples	13 examples	5 examples	0 example	90%

Detailed description of the invention

The present invention will be further described below to use 2 embodiments.

Embodiment 1:

Each crude drug is taken by following weight parts:

Pupa bombycis 6, Pheretima 20, Air Bladder pseudosciaenae seu Acipenser 13, Carapax Et Plastrum Testudinis 35, Ophicalcitum 5, achillea millefolium 15, Receptaculum Nelumbinis 20, Radix Polygalae fallacis 13, Herba Selaginellae 20, Fructus Leonuri 25, Rhizoma Wenyujin Concisum 20, the Cortex Eucommiae 15, Herba Siegesbeckiae 20, Flos Rosae Chinensis 15, Radix Aristolochiae 3, Radix Rhodiolae 20, Resina Ferulae 12, Calyx Kaki 5, Rhizoma valerianae latifoliae 5, yellow wine 30,60 degree of Chinese liquor 40.

1. get achillea millefolium, Receptaculum Nelumbinis, Radix Polygalae fallacis, Herba Selaginellae, Fructus Leonuri, Rhizoma Wenyujin Concisum, the Cortex Eucommiae, Herba Siegesbeckiae, Flos Rosae Chinensis, Radix Aristolochiae, Radix Rhodiolae, Resina Ferulae, Calyx Kaki, Rhizoma valerianae latifoliae clean, clean, dry, marmite is put in chopping, adding distil water decocts twice, first time adds the water soaking 5-12 hours of crude drug 10 times amount, after intense fire is fried boiling, slow fire boiling 3 hours, gets decocting liquid, filtration again, and second time adds the distilled water of crude drug 7 times amount, decoct 1.5 hours, get twice decocting liquid to merge, filter to obtain medicinal liquid, for subsequent use;

2. Pupa bombycis, Pheretima, Air Bladder pseudosciaenae seu Acipenser are cleaned, microwave drying, with gauze parcel patent medicine bag after chopping;

3. get Ophicalcitum to pound into fragment and put into Chinese liquor and stir, sealing immersion 17-20 days also together put into by medicated bag step 2. obtained again, then by medical filtration decontamination, heat 70-90 DEG C and make medicated wine precision be 8-12 degree, cooling leaves standstill 2 hours second time and filters;

4. Carapax Et Plastrum Testudinis is cleaned and dry, smash to pieces, add yellow wine moistening, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, 200 object fine powders must be, for subsequent use;

5. medicinal liquid step 1., 3. obtained merges, temperature is concentrated into the concentrated solution of relative density 1.04-1.10 at 60-70 DEG C, after temperature leaves standstill 24 hours at 4-7 DEG C, filter to obtain clarification medicinal liquid, in its medicinal liquid, add the raw material homogenizer that 4. step obtain carry out homogenizing, sterilizing, bottled, sterilization.

Embodiment 2:

Each crude drug is taken by following weight parts:

Pupa bombycis 7, Pheretima 22, Air Bladder pseudosciaenae seu Acipenser 13, Carapax Et Plastrum Testudinis 30, Ophicalcitum 6, achillea millefolium 18, Receptaculum Nelumbinis 15, Radix Polygalae fallacis 14, Herba Selaginellae 18, Fructus Leonuri 27, Rhizoma Wenyujin Concisum 23, the Cortex Eucommiae 17, Herba Siegesbeckiae 17, Flos Rosae Chinensis 12, Radix Aristolochiae 4, Radix Rhodiolae 23, Resina Ferulae 11, Calyx Kaki 6, Rhizoma valerianae latifoliae 7, yellow wine 27,60 degree of Chinese liquor 45.

1. get achillea millefolium, Receptaculum Nelumbinis, Radix Polygalae fallacis, Herba Selaginellae, Fructus Leonuri, Rhizoma Wenyujin Concisum, the Cortex Eucommiae, Herba Siegesbeckiae, Flos Rosae Chinensis, Radix Aristolochiae, Radix Rhodiolae, Resina Ferulae, Calyx Kaki, Rhizoma valerianae latifoliae clean, clean, dry, marmite is put in chopping, adding distil water decocts twice, first time adds the water soaking 5-12 hours of crude drug 10 times amount, after intense fire is fried boiling, slow fire boiling 3 hours, gets decocting liquid, filtration again, and second time adds the distilled water of crude drug 7 times amount, decoct 1.5 hours, get twice decocting liquid to merge, filter to obtain medicinal liquid, for subsequent use;

2. Pupa bombycis, Pheretima, Air Bladder pseudosciaenae seu Acipenser are cleaned, microwave drying, with gauze parcel patent medicine bag after chopping;

3. get Ophicalcitum to pound into fragment and put into Chinese liquor and stir, sealing immersion 17-20 days also together put into by medicated bag step 2. obtained again, then by medical filtration decontamination, heat 70-90 DEG C and make medicated wine precision be 8-12 degree, cooling leaves standstill 2 hours second time and filters;

4. Carapax Et Plastrum Testudinis is cleaned and dry, smash to pieces, add yellow wine moistening, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, 200 object fine powders must be, for subsequent use;

5. medicinal liquid step 1., 3. obtained merges, temperature is concentrated into the concentrated solution of relative density 1.04-1.10 at 60-70 DEG C, after temperature leaves standstill 24 hours at 4-7 DEG C, filter to obtain clarification medicinal liquid, in its medicinal liquid, add the raw material homogenizer that 4. step obtain carry out homogenizing, sterilizing, bottled, sterilization.

model case

Case one: not XX, female, 32 years old, expressway tol lcollection person, suffers from hypertension 3 years, blood pressure 160/100mmhg, frequent appearance is dizzy, insomnia, xerostomia and numb, with crossing multiple antihypertensive drugs, antihypertensive effect is not obvious, and blood pressure still controls bad, after take 2 courses for the treatment of of oral liquid of the present invention after, hypertension is obviously alleviated, then after continuing to take 2 courses for the treatment of, blood pressure recovers normal, and it is normal to follow up a case by regular visits to 3 months non-blood pressures.

Case two: Soviet Union XX, man, 56 years old, bank security, suffers from hypertension 5 years, does not have to record high pressure 180 during medication, low pressure 120, will eat depressor at ordinary times, but blood pressure still can not get controlling always, take 5 courses for the treatment of of oral liquid of the present invention continuously afterwards, blood pressure is just in normal range, and without the need to taking depressor again, drug withdrawal 1 year blood pressure does not come up, at normal value range yet.

Case three: permitted XX, man, 65 years old, temple manages, patient's hypertension 6 years, measuring blood pressure 170/95mmHg, with dizzy, dizzy, headache, insomnia and dreamful sleep, breathe hard, have palpitation, the complication such as arrhythmia, take Western medicine aspirin medicine blood pressure lowering effect not obvious, and complication is not felt any better throughout the year, after take the symptoms such as the present invention's 3 course of therapy dizzinesses, dizzy, headache, arrhythmia and obviously alleviate, blood pressure is down to 165/90mmHg, then continues to take 4 courses for the treatment of, and blood pressure is down to 135/80mmHg, symptom disappears completely, follows up a case by regular visits to and has no recurrence in 5 months.

Case four: permitted XX, man, 59 years old age, postman, patient often has a dizzy spell, cardiopalmus, dreaminess, the symptom such as weak, measuring blood pressure 175/95mmHg, adhere to Drug therapy over 2 years, blood pressure controls at normal range value always, but other symptom can not get improving always, take 3 courses for the treatment of of oral liquid of the present invention upon somebody's introduction, have a dizzy spell, cardiopalmus, dreaminess, weak wait transference cure, after take 2 courses for the treatment of again, blood pressure is down to 130/85mmHg and stablizes, symptom disappears completely, follows up a case by regular visits to and has no recurrence half a year, and blood pressure is at normal value range.

Claims (4)

1. a Fructus Leonuri oral liquid, is characterized in that: it is made up of the crude drug of following weight portion:

Pupa bombycis 5-10, Pheretima 20-25, Air Bladder pseudosciaenae seu Acipenser 10-15, Carapax Et Plastrum Testudinis 25-35, Ophicalcitum 5-7, achillea millefolium 15-20, Receptaculum Nelumbinis 10-20, Radix Polygalae fallacis 13-15, Herba Selaginellae 15-20, Fructus Leonuri 25-30, Rhizoma Wenyujin Concisum 20-25, the Cortex Eucommiae 15-22, Herba Siegesbeckiae 15-20, Flos Rosae Chinensis 10-15, Radix Aristolochiae 3-5, Radix Rhodiolae 20-25, Resina Ferulae 10-12, Calyx Kaki 5-8, Rhizoma valerianae latifoliae 5-8, yellow wine 25-30,60 degree of Chinese liquor 35-55.

2. Fructus Leonuri oral liquid according to claim 1, is characterized in that: described Fructus Leonuri oral liquid is made up of the crude drug of following weight portion:

Pupa bombycis 6, Pheretima 20, Air Bladder pseudosciaenae seu Acipenser 13, Carapax Et Plastrum Testudinis 35, Ophicalcitum 5, achillea millefolium 15, Receptaculum Nelumbinis 20, Radix Polygalae fallacis 13, Herba Selaginellae 20, Fructus Leonuri 25, Rhizoma Wenyujin Concisum 20, the Cortex Eucommiae 15, Herba Siegesbeckiae 20, Flos Rosae Chinensis 15, Radix Aristolochiae 3, Radix Rhodiolae 20, Resina Ferulae 12, Calyx Kaki 5, Rhizoma valerianae latifoliae 5, yellow wine 30,60 degree of Chinese liquor 40.

3. Fructus Leonuri oral liquid according to claim 1, is characterized in that: described Fructus Leonuri oral liquid is made up of the crude drug of following weight portion:

Pupa bombycis 7, Pheretima 22, Air Bladder pseudosciaenae seu Acipenser 13, Carapax Et Plastrum Testudinis 30, Ophicalcitum 6, achillea millefolium 18, Receptaculum Nelumbinis 15, Radix Polygalae fallacis 14, Herba Selaginellae 18, Fructus Leonuri 27, Rhizoma Wenyujin Concisum 23, the Cortex Eucommiae 17, Herba Siegesbeckiae 17, Flos Rosae Chinensis 12, Radix Aristolochiae 4, Radix Rhodiolae 23, Resina Ferulae 11, Calyx Kaki 6, Rhizoma valerianae latifoliae 7, yellow wine 27,60 degree of Chinese liquor 45.

4. the Fructus Leonuri oral liquid as described in claim 1 or 2 or 3, is characterized in that: it comprises the following steps:

1. get achillea millefolium, Receptaculum Nelumbinis, Radix Polygalae fallacis, Herba Selaginellae, Fructus Leonuri, Rhizoma Wenyujin Concisum, the Cortex Eucommiae, Herba Siegesbeckiae, Flos Rosae Chinensis, Radix Aristolochiae, Radix Rhodiolae, Resina Ferulae, Calyx Kaki, Rhizoma valerianae latifoliae clean, clean, dry, marmite is put in chopping, adding distil water decocts twice, first time adds the water soaking 5-12 hours of crude drug 10 times amount, after intense fire is fried boiling, slow fire boiling 3 hours, gets decocting liquid, filtration again, and second time adds the distilled water of crude drug 7 times amount, decoct 1.5 hours, get twice decocting liquid to merge, filter to obtain medicinal liquid, for subsequent use;

2. Pupa bombycis, Pheretima, Air Bladder pseudosciaenae seu Acipenser are cleaned, microwave drying, with gauze parcel patent medicine bag after chopping;

3. get Ophicalcitum to pound into fragment and put into Chinese liquor and stir, sealing immersion 17-20 days also together put into by medicated bag step 2. obtained again, then by medical filtration decontamination, heat 70-90 DEG C and make medicated wine precision be 8-12 degree, cooling leaves standstill 2 hours second time and filters;

4. Carapax Et Plastrum Testudinis is cleaned and dry, smash to pieces, add yellow wine moistening, after yellow wine absorbs completely, be placed in slow fire fried dry in frying pan, take out, be placed in mortar and grind into powder, 200 object fine powders must be, for subsequent use;

5. medicinal liquid step 1., 3. obtained merges, temperature is concentrated into the concentrated solution of relative density 1.04-1.10 at 60-70 DEG C, after temperature leaves standstill 24 hours at 4-7 DEG C, filter to obtain clarification medicinal liquid, in its medicinal liquid, add the raw material homogenizer that 4. step obtain carry out homogenizing, sterilizing, bottled, sterilization.