CN105106793A

CN105106793A - Granules for treating chronic bronchitis

Info

Publication number: CN105106793A
Application number: CN201510621414.0A
Authority: CN
Inventors: 戴文健
Original assignee: NANJING JINGYUN CHEMICAL Co Ltd
Current assignee: NANJING JINGYUN CHEMICAL Co Ltd
Priority date: 2015-09-25
Filing date: 2015-09-25
Publication date: 2015-12-02

Abstract

The invention relates to the field of traditional Chinese medicine and discloses granules for treating chronic bronchitis. The granules comprise, by weight, 28 parts of typha angustata rhizome, 20 parts of codonopsis convolvulacea, 18 parts of erigeron annuus, 25 parts of Asparagus filicinus Buch. -Ham. ex D. Don, 18 parts of rabdosia nervosa, 25 parts of radix peucedani, 20 parts of almond, 25 parts of radix stemonae, 22 parts of Chinese magnoliavine fruit, 20 parts of snakegourd fruit, 15 parts of tabasheer, 20 parts of Chinese fevervine herb, 15 parts of pubescent holly root, 25 parts of radix astragali, 15 parts of mulberry leaf, 25 parts of semen raphani, 20 parts of asparagus fern, 15 parts of dried radix rehmanniae, 20 parts of radix scrophulariae, 15 parts of Japanese ardisia herb and 5 parts of liquorice. The granules can treat chronic bronchitis.

Description

One treats chronic bronchitis granule

Technical field

The present invention relates to a kind of Chinese medicine, particularly relate to one and treat chronic bronchitis granule.

Background technology

Chronic bronchitis is the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa and surrounding tissue.Clinical with cough, expectoration for cardinal symptom, annual morbidity continues 3 months, continuous more than 2 years or 2 years.Need to get rid of the other diseases (as illness such as pulmonary tuberculosis, pneumoconiosis, pulmonary abscess, heart disease, cardiac insufficiency, bronchiectasis, bronchial asthma, chronic nasopharyngitis, esophageal reflux syndromes) with cough, expectoration, wheezing symptoms further.Slow onset, the course of disease is long, repeatedly acute attack and aggravation.Cardinal symptom is cough, expectoration, or with panting.Acute exacerbation means cough, expectoration, pant etc., and symptom increases the weight of suddenly.The main cause of acute exacerbation is respiratory tract infection, and pathogen can be virus, antibacterial, mycoplasma and chlamydia etc.The effect of current treatment product chronic bronchitis is all not so good, is therefore badly in need of a kind of Chinese medicine for the treatment of chronic bronchitis.

Summary of the invention

Goal of the invention: the object of the present invention is to provide one to treat chronic bronchitis granule and preparation method thereof.

Technical scheme: one treats chronic bronchitis granule, is prepared from: Rhizoma typhae 28 parts, Radix Codonopsis Convolvulaceae 20 parts, Herba Erigerontis Annui 18 parts, fern Radix Asparagi 25 parts, veined rabdosia herb 18 parts, Radix Peucedani 25 parts, 20 parts, Semen Armeniacae Amarum, the Radix Stemonae 25 parts, Fructus Schisandrae Chinensis 22 parts, Fructus Trichosanthis 20 parts, Concretio Silicea Bambusae 15 parts, Herba Paederiae 20 parts, Radix Ilicis Pubescentis 15 parts, the Radix Astragali 25 parts, 15 parts, Folium Mori, Semen Raphani 25 parts, Radix Asparagi 20 parts, 15 parts, the Radix Rehmanniae, Radix Scrophulariae 20 parts, Herba Ardisiae Japonicae 15 parts, 5 parts, Radix Glycyrrhizae by the Chinese medicine extraction of following weight parts.

Described treatment chronic bronchitis granule, preparation method: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch, granulate, make granule.

The application of described treatment chronic bronchitis granule in preparation treatment chronic bronchitis granule.

Rhizoma typhae be Typhaceae plant typha angustata or its belong to the rhizome with part tender stem of various plants together.Clearing away heat and cooling blood, inducing diuresis to remove edema.Control anemia of pregnant woman's consumptive fever, vaginal bleeding due to excessive movement of fetus, quench one's thirst, aphtha, hematodiarrhoea, gonorrhea, leucorrhea, edema, scrofula.

Radix Codonopsis Convolvulaceae be Campanulaceae Radix Codonopsis Convolvulaceae Codonopsisconvolvulaceakurz descend tuber dryly, invigorating QI and blood, the lung moistening and production of body fluid promoting.For anemia, spontaneous perspiration, deficiency of lung-YIN is coughed, neurasthenia.

Herba Erigerontis Annui is Compositae Herba Erigerontis aceris platymiscium Herba Erigerontis Annui Erigeronannuus (L.) Pers., with all herbal medicine.Summer, autumn gather.Heat-clearing and toxic substances removing, malaria.Acute gastroenteritis, malaria; Gingivitis is controlled in external, venom.

Fern Radix Asparagi is Liliaceae asparagus plant asparagus filicicum Ham AsparagusfilicinusBuch.-Ham., is used as medicine with tuber.Autumn excavates, and cleans, goes crust to dry or cook to dry in the shade.Nourishing the lung to arrest cough.For pulmonary tuberculosis chronic cough, lung abscess, pertussis, sputum with blood, bronchial asthma.Other Chinese medicines are pharmacopeia kind.

Beneficial effect: the traditional Chinese medical science is thought, causes the cause of disease of chronic bronchitis, and lung, spleen, the dirty virtual loss of kidney three are this, and the damp that is affected by the cold is mark, in addition, also relevant with lung sthenia hepatic heat.Rhizoma typhae of the present invention, Radix Codonopsis Convolvulaceae, Herba Erigerontis Annui, fern Radix Asparagi, veined rabdosia herb, Radix Peucedani, Semen Armeniacae Amarum, the Radix Stemonae, Fructus Schisandrae Chinensis, Fructus Trichosanthis, Concretio Silicea Bambusae heat-clearing and toxic substances removing, cold expelling lung heat clearing, pleasantly reduce phlegm as monarch drug, Herba Paederiae, Radix Ilicis Pubescentis, the Radix Astragali, Folium Mori, Semen Raphani, Radix Asparagi, the Radix Rehmanniae, Radix Scrophulariae, the gentle sending down the abnormal ascending QI of Herba Ardisiae Japonicae are ministerial drug, Radix Glycyrrhizae is adjuvant, full side treats chronic bronchitis, respond well.

Detailed description of the invention

Embodiment 1: Qu Rhizoma typhae 28g, Radix Codonopsis Convolvulaceae 20g, Herba Erigerontis Annui 18g, fern Radix Asparagi 25g, veined rabdosia herb 18g, Radix Peucedani 25g, Semen Armeniacae Amarum 20g, Radix Stemonae 25g, Fructus Schisandrae Chinensis 22g, Fructus Trichosanthis 20g, Concretio Silicea Bambusae 15g, Herba Paederiae 20g, Radix Ilicis Pubescentis 15g, Radix Astragali 25g, Folium Mori 15g, Semen Raphani 25g, Radix Asparagi 20g, Radix Rehmanniae 15g, Radix Scrophulariae 20g, Herba Ardisiae Japonicae 15g, Radix Glycyrrhizae 5g, adds the water of medical material 10 times of weight, soaks 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, and merges twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adds ethanol and makes the percent by volume of alcohol content reach 75%, stirs, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, and temperature of charge is 70 DEG C, and atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch 50g, granulate, make granule.

Embodiment 2: the present invention treats the clinical data of chronic bronchitis

Clinical medicine: prepare granule of the present invention by above-described embodiment 1, when taking each 1 bag, every bag of 20g, every day 3 times 30 days is a course for the treatment of.The routine patient of clinical observation 50.

Diagnostic criteria: clinically with cough, expectoration for cardinal symptom or with panting, annual morbidity continues three months, and continuous 2 years or more.Though to coughing clinically, expectorant, asthma shape continuous 2 years or more, annual morbidity continues not enough trimestral patient, also diagnosable according to (as x-ray, pulmonary function etc.) if any clear and definite objective determination.Get rid of the Other diseases (as pulmonary tuberculosis, pneumoconiosis, pulmonary abscess, heart disease, cardiac insufficiency, bronchiectasis, bronchial asthma, chronic nasopharynx illness etc.) with cough, expectoration, wheezing symptoms.

Observation of curative effect: recovery from illness: cough, expectorant, breathe heavily, the cardinal symptom basic controlling such as scorching, stable disease, without recidivist.Effective: the state of an illness is relatively stable, attack times and degree obviously alleviate, medical science | and education network collects ordinary circumstance (comprising diet, sleep, the muscle power etc.) person of having clear improvement.Effective: the state of an illness is understable, but attack times and degree alleviate, ordinary circumstance improvement person.Invalid: attack times, degree and ordinary circumstance are without improvement or add severe one.

Result: recovery from illness 15 example, effective 10 examples, effective 18 examples, invalid 5 examples, total effective rate 86%, and have no side effect.

Claims

1. a treatment chronic bronchitis granule, it is characterized in that, be prepared from: Rhizoma typhae 28 parts, Radix Codonopsis Convolvulaceae 20 parts, Herba Erigerontis Annui 18 parts, fern Radix Asparagi 25 parts, veined rabdosia herb 18 parts, Radix Peucedani 25 parts, 20 parts, Semen Armeniacae Amarum, the Radix Stemonae 25 parts, Fructus Schisandrae Chinensis 22 parts, Fructus Trichosanthis 20 parts, Concretio Silicea Bambusae 15 parts, Herba Paederiae 20 parts, Radix Ilicis Pubescentis 15 parts, the Radix Astragali 25 parts, 15 parts, Folium Mori, Semen Raphani 25 parts, Radix Asparagi 20 parts, 15 parts, the Radix Rehmanniae, Radix Scrophulariae 20 parts, Herba Ardisiae Japonicae 15 parts, 5 parts, Radix Glycyrrhizae by the Chinese medicine extraction of following weight parts.

2. treat chronic bronchitis granule as claimed in claim 1, it is characterized in that, preparation method: get above-mentioned Chinese medicine, add the water of medical material 10 times of weight, soak 0.5h, decoct 1 hour, filter, medicinal residues add the water of medical material 8 times of weight again, decoct 1 hour, medicinal liquid leaches, merge twice decoction liquor, being evaporated to 60 DEG C of relative densities is 1.05, adding ethanol makes the percent by volume of alcohol content reach 75%, stir, leave standstill, filter, during filtrate reduced in volume to 65 DEG C, relative density is 1.25, and reclaim ethanol, obtain concentrated solution, by concentrated solution spraying dry, spray drying condition is: inlet temperature is 100 DEG C, leaving air temp is 90 DEG C, temperature of charge is 70 DEG C, atomizing pressure is 0.2 MPa, spray velocity is 10ml/s, add starch, granulate, make granule.

3. treat the application of chronic bronchitis granule in treatment chronic bronchitis granule as claimed in claim 1.