CN105106439A - Traditional Chinese medicine for treating hiccup - Google Patents

Abstract

The invention relates to a traditional Chinese medicine for treating hiccup. The traditional Chinese medicine is prepared by adopting the following raw materials in part by weight; 30 parts of sticktight, 12 parts of semen canavaliae, 10 parts of agilawood, 9 parts of inula flower, 9 parts of persimmon calyx, 9 parts of orange peel, 9 parts of caulis perllae and 12 parts of mangnolia officinalis. A clinical experiment proves that the traditional Chinese medicine can safely and efficiently treat hiccup.

Description

A kind of Chinese medicine being used for the treatment of singultus

Technical field

The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of singultus.

Background technology

Singultus is diaphragm spasm, belongs to diaphragmatic function obstacle disease, and during air-breathing, glottis is closed suddenly produces one oh sound, and the contractile motion of this diaphram exception is caused by vagus nerve and phrenic nerves are upset.Singultus is a kind of symptom clinically, causes the reason of singultus a lot, as too fast in usually taken food, and enters irritable food and suck cold air etc. to produce singultus, and the lighter is interrupted and has the hiccups, and severe one can singultus or vomiting continuously, abdominal distention, stomachache, indivedual urinary incontinence etc.Normal person also can because taking food too fast, feed irritable food and suck cold air and produce singultus.Majority can stop within the short time, and serious brain diseases, uremia, breast abdomen diseases also can cause singultus.Also singultus phenomenon can be there is in part breast, abdominal postoperative disease.Singultus is the common complication of patients with cerebral apoplexy, once occur often being difficult to natural remission.Singultus is frequent or lasting more than 24h person, is called intractable or intractable singultus clinically.Singultus divides periphery property and central.Singultus with between larynx oh repeatedly, sound is short and frequently, and making us can not from being only main manifestations.The cause of disease is improper diet mainly, and feelings will is unsuccessful, weakness of the spleen and stomach etc., and the sick position of singultus is at diaphragm, and the crucial internal organs of pathological changes are stomach, relevant with lung, liver, kidney.Main pathogenesis is that adverse rising of stomach-QI moves diaphragm.Therapeutic Principle is regulating qi-flowing for harmonizing stomach, lowering the adverse QI to relieve hiccough, and on the basis distinguishing cold and heat and asthenia and sthenia, imposes the method for cold relieving, heat clearing away, tonify deficiency, removing the relative excess respectively.For the singultus occurred in critical illness card, anxious when rescue gastric qi.

Medical material present Research involved in the present invention is as follows:

Herba Bidentis Bipinnatae [another name] terrible hairpin grass, terrible Hemerocallis citrina Baroni, Shandong lao-ya-tsao, Herba Bidentis Bipinnatae, terrible spicule, Herba Bidentis Bipinnatae, look into the distance Staphasagria, bean dregs dish, fork woman, lead-in wire bag, pin bag grass, pin, thorn ghost, terrible Fructus Tribuli, black rattan dish, clearing stomach grass, walk with people, sticky colorful clothes, terrible chrysanthemum, beat and bore grass, mountain louse mother, glue body grass, bidens, Herba silenes fortunei, little Bidens bipinnata, Suo Renyi, Rhizoma Homalomenae.[source] is the herb of feverfew Herba Bidentis Bipinnatae.To gather between summer, autumn aerial parts, dry.[nature and flavor] bitter in the mouth is flat, nontoxic.[function cures mainly] heat clearing away, removing toxic substances, dissipating blood stasis, detumescence.Treating malaria disease, diarrhoea, dysentery, hepatitis, acute nephritis, stomachache, dysphagic, acute appendicitis, laryngopharynx swelling and pain, traumatic injury, snake bite and insect sting.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[attention] is not taken by pregnant women.[extracts] " China's book on Chinese herbal medicine ".

Sword Jackbean Seed [another name] holds sword bean, wild knife plate rattan, Ge Dou, cutter dam bean, large Semen Canavaliae, Semen Canavaliae angle, sheath bean under the arm.[source] this product is the dry mature seed of leguminous plant Semen Canavaliae, shell and root.To gather autumn mature fruit, strip seed, dry.[nature and flavor] are sweet, temperature.[return through] returns stomach, kidney channel.[function cures mainly] seed: warming middle-JIAO to send down the adverse QI, the kidney invigorating.For deficiency and coldness singultus, suffer from a deficiency of the kidney, lumbago, stomachache; Shell: restore menstrual flow and invigorate blood circulation, antidiarrheal.For lumbago, chronic dysentery, amenorrhea; Root: eliminating stasis to stop pain.For traumatic injury, lumbago.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.The careful clothes of [attention] gastric heat Sheng person.[extracts] " China's book on Chinese herbal medicine ".

Gal is muttered, and perfume (or spice) [another name] agalloch eaglewood, fine jade are muttered, strange nanmu.The timber containing volume resin that [source] is Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum or the nearly root of Lignum Aquilariae Resinatum.Choose Lignum Aquilariae Resinatum medium oil (resin) foot, body constitution is heavy and timber stick that property is glutinous, its oil-containing of pruning is few and part that color is light.[nature and flavor] acrid in the mouth is peppery, and temperature is nontoxic.[return through] returns spleen, stomach, lung, kidney channel.[function cures mainly] warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.For Deficiency and coldness of spleen and stomach, singultus is vomitted, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

Flos Inulae [another name] Herba Inulae [herb], June chrysanthemum, drum flower, drip drip gold, little Hemerocallis citrina Baroni, money, donkey dish.[source] this product is the dry capitulum of feverfew Flos Inulae or Inula britannica.Summer, season in autumn two, the flowers are in blossom gathers when putting, and removing impurity, dries in the shade or dry.[nature and flavor] are bitter, pungent, salty, tepor.[return through] returns lung, spleen, stomach, large intestine channel.[function cures mainly] sending down the abnormal ascending QI, expectorant, row water, preventing or arresting vomiting.For cough due to wind and cold, phlegm retention stores knot, chest and diaphragm feeling of fullness, dyspnea and cough with excessive sputum, vomiting eructation, epigastric oppression and rigidity.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

Calyx Kaki [another name] Fructus Kaki money, Fructus Kaki fourth, Fructus Kaki handle, Fructus Kaki calyx.[source] this product is the dry Constellation calyx of Ebenaceae plant Fructus Kaki.Pluck during fruit maturation in winter, collect time edible, clean, dry.[nature and flavor] are bitter, puckery, flat.[return through] returns stomach warp.[function cures mainly] lowering the adverse flow of QI.For singultus.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

Pericarpium Citri tangerinae [another name] Pericarpium Citri Reticulatae.[source] this product is the dry mature skin of rutaceae orange and variety thereof.Medical material is divided into " Pericarpium Citri Reticulatae " and " Pericarpium citri reticuatae chachiensis ".Harvesting ripe fruit, strips peel, dries or cold drying.[nature and flavor] are bitter, pungent, temperature.[return through] returns lung, spleen channel.[function cures mainly] regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".

Caulis Perillae [another name] Caulis Perillae, Folium Perillae stem, Folium Perillae bar.[source] is the stem of labiate wrinkle Folium Perillae, sharp Folium Perillae etc.Qiu Wei, extracts aerial parts, and removing sprig, blade and fruit, dry.Or when gathering Folium Perillae late summer, cutting thick stalk and drying.The former is called " old Caulis Perillae ", and the latter is called " tender Caulis Perillae ".[nature and flavor] are pungent, temperature.[return through] enters spleen, stomach, lung three warp.[function cures mainly] regulating the flow of QI to ease the stomach, pain relieving, antiabortive.Vexed for chest and diaphragm painful abdominal mass, gastralgia, belch is vomitted, frequent fetal movement.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[attention] [extracts] " China's book on Chinese herbal medicine ".

Cortex Magnoliae Officinalis [another name] Cortex Magnoliae Officinalis, CORTEX MAGNOLIAE OFFICINALIS.[source] this product is the dry dried bark of Magnoliacea plant Cortex Magnoliae Officinalis or magnolia officinalis rehd.et wils.var.biloba rehd.et wils., root bark and branch skin.4 ~ June strips, root bark and branch skin Directly Dried in Shadow; Dried bark put in boiling water micro-boil after, dark and damp place of banking up, when " diaphoresis " is to inner surface purpling brown or sepia, steams soft, takes out, is rolled into tubular, dry.[nature and flavor] are bitter, pungent, temperature.[return through] returns spleen, stomach, lung, large intestine channel.The expectorant of [function cures mainly] dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is cautious use of.Rhizoma Zingiberis makes for it.Dislike Rhizoma Alismatis, Mirabilitum crystallina, Sal Nitri.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention aims to provide a kind of Chinese medicine being used for the treatment of singultus, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing singultus.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a Chinese medicine for singultus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Bidentis Bipinnatae 30 parts, Sword Jackbean Seed 12 parts, gal mutter fragrant 10 parts, Flos Inulae 9 parts, Calyx Kaki 9 parts, Pericarpium Citri tangerinae 9 parts, Caulis Perillae 9 parts, Cortex Magnoliae Officinalis 12 parts.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, physical data

Outpatient service is collected and singultus patient 72 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 35 example and matched group 37 example at random, treatment group man 20 example, female 15 example, 53.7 years old mean age; Matched group man 21 example, female 16 example, 52.1 years old mean age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.

Diagnostic criteria

Diagnostic criteria according to the meeting of national singultus clinical speciality: (1). clinical manifestation with between larynx oh repeatedly, sound is short and frequently, and making us can not from being only primary symptom; (2). normal companion's chest and diaphragm painful abdominal mass is vexed, and upset in the stomach is scorching hot, belch, and emotion uneasiness waits disease; (3). have that improper diet, feelings will are unsuccessful, the risk factor such as to suffer from cold, onset is more anxious more; (4). singultus does the inspections such as gastrointestinal barium agent X-ray examination and endoscope after controlling, and contributes to diagnosis.

2, test method

2.1 Therapeutic Method

The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.Within 7 days, be a course for the treatment of, observe the curative effect after 2 weeks.

The oral lignocaine 10ml of matched group, every day takes for 3 times after the meal, within 7 days, is a course for the treatment of, observe the curative effect after 2 weeks.

3, criterion of therapeutical effect and therapeutic outcome

3.1 criterion of therapeutical effect

Clinic control: singultus disappears and nothing recurrence in the recent period;

Effective: singultus symptom alleviates or seizure frequency reduces;

Invalid: singultus symptom does not alleviate, and attack times does not reduce.

3.2 therapeutic outcomes are in table 1.

Table 1 liang group comparitive study

Group	n	Clinic control	Effectively	Invalid	Total effective rate (%)	Serious adverse reaction example
							Treatment group	35	15	18	2	94.3%	0
Matched group	37	7	12	18	51.4%	0

Visible, the medicine that the present invention obtains can safe and effective cure hiccup, has promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Herba Bidentis Bipinnatae 30 grams, Sword Jackbean Seed 12 grams, gal mutter fragrant 10 grams, Flos Inulae 9 grams, Calyx Kaki 9 grams, Pericarpium Citri tangerinae 9 grams, Caulis Perillae 9 grams, Cortex Magnoliae Officinalis 12 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of singultus.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 2

Take: Herba Bidentis Bipinnatae 30 grams, Sword Jackbean Seed 12 grams, gal mutter fragrant 10 grams, Flos Inulae 9 grams, Calyx Kaki 9 grams, Pericarpium Citri tangerinae 9 grams, Caulis Perillae 9 grams, Cortex Magnoliae Officinalis 12 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of singultus.Oral, every bu Morning Afternoon Evening is taken for three times.

Embodiment 3

Take: Herba Bidentis Bipinnatae 30 grams, Sword Jackbean Seed 12 grams, gal mutter fragrant 10 grams, Flos Inulae 9 grams, Calyx Kaki 9 grams, Pericarpium Citri tangerinae 9 grams, Caulis Perillae 9 grams, Cortex Magnoliae Officinalis 12 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of singultus.Oral, every bu Morning Afternoon Evening is taken for three times.

Claims (4)

1. be used for the treatment of a Chinese medicine for singultus, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Bidentis Bipinnatae 30 parts, Sword Jackbean Seed 12 parts, gal mutter fragrant 10 parts, Flos Inulae 9 parts, Calyx Kaki 9 parts, Pericarpium Citri tangerinae 9 parts, Caulis Perillae 9 parts, Cortex Magnoliae Officinalis 12 parts.

2. be used for the treatment of the Chinese medicine of singultus as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Bidentis Bipinnatae 30 parts, Sword Jackbean Seed 12 parts, gal mutter fragrant 10 parts, Flos Inulae 9 parts, Calyx Kaki 9 parts, Pericarpium Citri tangerinae 9 parts, Caulis Perillae 9 parts, Cortex Magnoliae Officinalis 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.

3. be used for the treatment of the Chinese medicine of singultus as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Bidentis Bipinnatae 30 parts, Sword Jackbean Seed 12 parts, gal mutter fragrant 10 parts, Flos Inulae 9 parts, Calyx Kaki 9 parts, Pericarpium Citri tangerinae 9 parts, Caulis Perillae 9 parts, Cortex Magnoliae Officinalis 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.

4. be used for the treatment of the Chinese medicine of singultus as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Bidentis Bipinnatae 30 parts, Sword Jackbean Seed 12 parts, gal mutter fragrant 10 parts, Flos Inulae 9 parts, Calyx Kaki 9 parts, Pericarpium Citri tangerinae 9 parts, Caulis Perillae 9 parts, Cortex Magnoliae Officinalis 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.