CN105073981A - 动物中性成熟的控制 - Google Patents
动物中性成熟的控制 Download PDFInfo
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/873—Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
- C12N15/877—Techniques for producing new mammalian cloned embryos
- C12N15/8778—Swine embryos
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/101—Bovine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US201261720187P | 2012-10-30 | 2012-10-30 | |
| US61/720,187 | 2012-10-30 | ||
| US201361870510P | 2013-08-27 | 2013-08-27 | |
| US61/870,510 | 2013-08-27 | ||
| PCT/US2013/067502 WO2014070887A1 (en) | 2012-10-30 | 2013-10-30 | Control of sexual maturation in animals |
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| CN105073981A true CN105073981A (zh) | 2015-11-18 |
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| CN201380067471.8A Pending CN105073981A (zh) | 2012-10-30 | 2013-10-30 | 动物中性成熟的控制 |
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| US (1) | US20140123330A1 (https=) |
| EP (1) | EP2914714A4 (https=) |
| JP (2) | JP2015533284A (https=) |
| KR (1) | KR20150100651A (https=) |
| CN (1) | CN105073981A (https=) |
| AP (1) | AP2015008495A0 (https=) |
| AR (1) | AR093291A1 (https=) |
| AU (1) | AU2013337951B2 (https=) |
| BR (1) | BR112015009589A2 (https=) |
| CA (1) | CA2889502A1 (https=) |
| MX (1) | MX2015005255A (https=) |
| NZ (1) | NZ629578A (https=) |
| PH (1) | PH12015500957A1 (https=) |
| RU (1) | RU2015120467A (https=) |
| WO (1) | WO2014070887A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109790551A (zh) * | 2016-06-16 | 2019-05-21 | 奥斯陆大学医院Hf | 改进的基因编辑 |
| CN111616830A (zh) * | 2020-07-03 | 2020-09-04 | 宁夏大学 | 一种新型icr小鼠超数排卵方法 |
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| US10920242B2 (en) | 2011-02-25 | 2021-02-16 | Recombinetics, Inc. | Non-meiotic allele introgression |
| US10323236B2 (en) | 2011-07-22 | 2019-06-18 | President And Fellows Of Harvard College | Evaluation and improvement of nuclease cleavage specificity |
| GB201122458D0 (en) | 2011-12-30 | 2012-02-08 | Univ Wageningen | Modified cascade ribonucleoproteins and uses thereof |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| PL3360964T3 (pl) | 2012-12-06 | 2020-03-31 | Sigma-Aldrich Co. Llc | Modyfikacja i regulacja genomu oparta na crispr |
| RU2662932C2 (ru) | 2013-03-14 | 2018-07-31 | Карибо Биосайенсиз, Инк. | Композиции и способы с участием нуклеиновых кислот, нацеленных на нуклеиновые кислоты |
| US20140359796A1 (en) * | 2013-05-31 | 2014-12-04 | Recombinetics, Inc. | Genetically sterile animals |
| US9163284B2 (en) | 2013-08-09 | 2015-10-20 | President And Fellows Of Harvard College | Methods for identifying a target site of a Cas9 nuclease |
| US9322037B2 (en) | 2013-09-06 | 2016-04-26 | President And Fellows Of Harvard College | Cas9-FokI fusion proteins and uses thereof |
| US9526784B2 (en) | 2013-09-06 | 2016-12-27 | President And Fellows Of Harvard College | Delivery system for functional nucleases |
| US9228207B2 (en) | 2013-09-06 | 2016-01-05 | President And Fellows Of Harvard College | Switchable gRNAs comprising aptamers |
| US10779518B2 (en) | 2013-10-25 | 2020-09-22 | Livestock Improvement Corporation Limited | Genetic markers and uses therefor |
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| JP2015533284A (ja) | 2015-11-24 |
| AU2013337951A1 (en) | 2015-06-11 |
| BR112015009589A2 (pt) | 2017-11-14 |
| CA2889502A1 (en) | 2014-05-08 |
| JP2019047794A (ja) | 2019-03-28 |
| AP2015008495A0 (en) | 2015-05-31 |
| EP2914714A4 (en) | 2016-09-21 |
| NZ629578A (en) | 2017-06-30 |
| MX2015005255A (es) | 2015-10-29 |
| EP2914714A1 (en) | 2015-09-09 |
| AU2013337951B2 (en) | 2019-10-03 |
| RU2015120467A (ru) | 2016-12-20 |
| PH12015500957A1 (en) | 2015-08-10 |
| US20140123330A1 (en) | 2014-05-01 |
| KR20150100651A (ko) | 2015-09-02 |
| WO2014070887A1 (en) | 2014-05-08 |
| AR093291A1 (es) | 2015-05-27 |
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