CN105039027B - A kind of freckle removing and whitening beauty soap and preparation method thereof - Google Patents
A kind of freckle removing and whitening beauty soap and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of freckle removing and whitening beauty soap, and by weight, its raw material includes：20 35 parts of babassu oil, 10 15 parts of zanthoxylum oil, 38 parts of prinsepia utilis royle oil, 25 parts of mink oil, 25 parts of highland barley bran, 15 20 parts of deionized water, 69 parts of sodium hydroxide, 38 parts of Yuan roots aqueous extract, 26 parts of sundew aqueous extract, 13 parts of edelweiss ethanol extract, 13 parts of fructus choerospondiatis ethanol extract, 13 parts of Asiatic sweet leaf ethanol extract.The freckle removing and whitening beauty soap of the present invention adds a variety of Traditional tibetan nationality medicine extracts and is made, can effective cleaning skin, and with obvious nti-freckle, whitening function, and raw material sources in natural, without sensation of dryness, stingless excitation after use.
Description
Technical field
The invention belongs to fine chemistry industry commodity technical field, and in particular to be a kind of freckle removing and whitening beauty soap and its system
Preparation Method.
Background technology
Soap is a kind of ancient personal cleansing articles for use, and it is mainly formed by animal and plant fat saponification.Due to soap
Various compositions are easily biodegradable, and are easy to by the microorganism decomposition in sewage disposal process, therefore will not cause river, lake
With the pollution problem of water channel, in addition, soapmaking falls within natural, reproducible resource with grease, thus production process to environment also without
Harm.But since the middle of last century, the rapid development of synthesis chemistry and petrochemical industry, provided for the production of synthetic detergent
Substantial amounts of cheap raw material, the fast developments of various personal synthesis of detergent articles for use is also promoted, it is all kinds of that there is cleaning, skin care effect
Mildy wash, face cleaning milk product continue to bring out, these products contain a variety of surfactants, its pH value deviation faintly acid, have one
Fixed cleaning performance, and there is certain skin care effect, by the extensive welcome of people；And traditional soap has due to it
There is simple cleaning function and alkalescence is stronger, its use range is constantly reducing.However, into after the new century, with these
Synthesis of detergent product long-term and widely use, its problem also constantly displays, as surfactant and preservative remain in
On skin, it is difficult to clean, cause skin allergic reaction occur；The cleaning dynamics of the products such as mildy wash is inadequate, it is difficult to cleans skin
On greasy dirt etc.；In addition, sewage caused by these cleaning products easily causes the eutrophication of environment, and processing cost is higher, right
Environmental pollution is larger, and its production process can also cause new pollution to environment.Therefore, people start to modern way of life
Introspected and changed, people increasingly tended to using nature, the cleaning product day such as pure, green product, conventional soap
Benefit is favored by people, in addition, traditional soap, in addition to preferable cleaning action is retained, people also begin to add shield thereto
Skin composition, strengthen its skin care effect, which also promotes the popularization of these products and development.
Traditional skin-protection soap, in the selection of grease, more from coconut oil, palm oil as its base oil, coconut oil energy
Abundant foam is produced, degreasing power is strong, but also easily causes the symptoms such as cleaning is excessive, and skin appearance is dry and astringent, itch, excitement,
Damage is easily caused for sensitive skin type.Palm oil is the filling oil commonly used in soap, can increase finished product hardness, but its nutrition into
Divide content relatively low, be unfavorable for product and play skin care effect.
In order to solve the above problems, the present invention is from babassu oil, highland barley bran, prinsepia utilis royle oil, zanthoxylum oil, mink
It is oily based on oil, and add the extract solution of the Tibetan medicines such as Yuan roots, sundew, edelweiss, fructus choerospondiatis, Asiatic sweet leaf, action temperature and, it is stingless
Swash, and the effect of freckle removing and whitening can be effectively played, moreover, above-mentioned Tibetan medicine is used cooperatively, the freckle removing and whitening for skin there are no
Corresponding product and report.
The content of the invention
It is an object of the invention to provide a kind of whitening spot-removing beauty soap, the beauty soap adds a variety of Traditional tibetan nationality medicine extracts and made
Form, can effective cleaning skin, and with obvious nti-freckle, whitening function, and raw material sources in natural, without dry and astringent after use
Sense, stingless excitation.
In order to realize foregoing invention purpose, technical scheme is as follows：
A kind of freckle removing and whitening beauty soap, by weight, its raw material includes：Babassu oil 20-35 parts, zanthoxylum oil 10-
15 parts, prinsepia utilis royle oil 3-8 parts, mink oil 2-5 parts, highland barley bran 2-5 parts, deionized water 15-20 parts, sodium hydroxide 6-9 parts,
Yuan root aqueous extract 3-8 parts, sundew aqueous extract 2-6 parts, edelweiss ethanol extract 1-3 parts, fructus choerospondiatis ethanol extract 1-3
Part, Asiatic sweet leaf ethanol extract 1-3 parts.
Wherein, the preparation method of Yuan root aqueous extracts is in described raw material components：After Yuan roots crush, 40 mesh sieves are crossed, are claimed
1Kg is taken, extracting in water is twice：Add 10L water for the first time, boil extraction 2h；Second of addition 10L water, boils extraction 2h；Filtering,
Merge the decoction extracted twice, after decoction 6000r/min centrifugations, heating is concentrated into 1L, obtains the Yuan roots water that concentration is 1g/mL and extracts
Liquid.
Wherein, the preparation method of sundew aqueous extract is in the raw material components：After sundew crushes, 40 mesh sieves are crossed,
1Kg is weighed, extracting in water is twice：12L water is added for the first time, boils extraction 2h；Second of addition 10L water, boils extraction 2h；Cross
Filter, merge the decoction extracted twice, after decoction 6000r/min centrifugations, heating is concentrated into 1L, obtains the sundew that concentration is 1g/mL
Aqueous extract.
Wherein, the preparation method of edelweiss ethanol extract is in the raw material components：After edelweiss crushes, 40 mesh are crossed
Sieve, 1Kg is weighed, add the extraction of 70% alcohol reflux twice：The ethanol of 8L 70%, refluxing extraction 1.5h are added for the first time；Second
Add the ethanol of 6L 70%, refluxing extraction 1.5h；Filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, obtain concentration
For 1g/mL edelweiss ethanol extract.
Wherein, the preparation method of fructus choerospondiatis ethanol extract is in the raw material components：After fructus choerospondiatis crushes, 40 mesh sieves are crossed, are claimed
1Kg is taken, adds the extraction of 60% alcohol reflux twice：The ethanol of 10L 60%, refluxing extraction 1.5h are added for the first time；Second of addition
The ethanol of 8L 60%, refluxing extraction 1.0h；Filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, it is 1g/ to obtain concentration
ML fructus choerospondiatis ethanol extract.
Wherein, the preparation method of Asiatic sweet leaf ethanol extract is in the raw material components：After Asiatic sweet leaf crushes, 40 mesh sieves are crossed, are claimed
1Kg is taken, adds the extraction of 70% alcohol reflux twice：The ethanol of 10L 70%, refluxing extraction 1.5h are added for the first time；Second of addition
The ethanol of 6L 70%, refluxing extraction 1.0h；Filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, it is 1g/ to obtain concentration
ML Asiatic sweet leaf ethanol extract.
Wherein, preparation process of the invention is：
(1) by above-mentioned prescription weight proportion take babassu oil, zanthoxylum oil, prinsepia utilis royle oil, mink oil, highland barley bran according to
In secondary addition stainless steel cauldron, 50 DEG C are heated with stirring to, is fully mixed, and 50 DEG C of keeping temperature, it is standby；
(2) ionized water and sodium hydroxide are removed by above-mentioned prescription weight proportion, sodium hydroxide is slowly added in water, side
Edged is quickly stirred with alkaline-resisting agitator, and sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；
(3) aqueous slkali is slowly added in the miscella that step (1) mixes, side bevelling is quickly stirred with alkaline-resisting agitator
Mix, the mixed liquor to sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；
(4) added while stirring in soap lye Yuan roots aqueous extract, sundew aqueous extract, edelweiss ethanol extract,
Fructus choerospondiatis ethanol extract and Asiatic sweet leaf ethanol extract, 30-60 minutes are stirred, obtain mixing soap lye；
(5) mixing soap lye is poured into mould, cooling placement 24-48h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；
(6) after being stripped, product continues to be placed on aging 30-60 days at shady and cool ventilation, that is, the freckle removing and whitening for obtaining the present invention is beautiful
Hold soap finished product.
The Action Specification of primary raw material in the present invention：
The present invention is from oil based on babassu oil, highland barley bran, prinsepia utilis royle oil, zanthoxylum oil, mink oil.
Babassu oil is the grease extracted from Brazilian Babassu palm nutmeat, contains abundant laurate, property
Matter is higher than coconut oil similar to coconut oil, the cleaning force of babassu oil, and moisturizing degree is better than coconut oil, but its property is than coconut oil temperature
With, and with the resisting pathogenic microbes effect such as antibacterium, antimycotic, it is adapted to all kinds skin to use.
Highland barley bran is a kind of grease of high-quality, and rich in unrighted acid, wherein linoleic acid content reaches 60%
More than.It has nourishing brain cell, adjusts the effect of vegetative nerve function, participates in the contraction of human smooth muscle, lipid metabolism
The activity of enzyme, the synthesis of prostaglandin and other physiological activities.It is clinically used for adjusting the treatment of serum cholesterol, artery sclerosis
And prevent, prevent neurological disorders etc., it can be rated as " nutrition oil ".Moreover, contain abundant vitamin A, dimension in highland barley bran
The antioxidant contents such as raw plain E, protein, amino acid and nicotinic acid, have the generation of suppression melanin, whitening, suppression Skin Cell old
The effect of change.
Prinsepia utilis royle oil is the conventional a kind of edible oil of Tibetan, Naxi, Bai nationality, the saturated fatty acid of prinsepia utilis royle oil, single
Unrighted acid, the content of multiple unrighted acid threes are balanced.Prinsepia utilis royle oil is free of harmful erucic acid, and contains
Abundant vitamin A. D. E, K etc., its composition is very close with human body lipid, nutritionist be described as " eatable cosmetics " and
" mankind supplement the new sources of essential fatty acid ", is rare pure natural advanced health care product.Because prinsepia utilis royle oil is rich
Containing unrighted acid, and its composition approaches with human sebaceous's class, and it has skin regeneration technique and moisture-keeping function；Have simultaneously
Extremely strong skin permeability, the effect similar with azone can be played.
Mink oil be found so far with human subcutaneous fat natural oil the most approximate, it is easily by the skin of people
Absorbed, there is optimal skin compatibility.It can obtain moisture from compared with internal layer cell, epidermis is moistened once again, with other
Grease is dramatically different, and after mink oil, skin is comfortable without greasy feeling, human body sensory.In addition, mink oil also has well
Anti-sunlight function, and there is good stability.
Zanthoxylum oil is the grease squeezed from Chinese prickly ash seed, and it mainly contains aliphatic acid, volatile oil, amino acid, micro
The compositions such as element, wherein, aliphatic acid is based on the compositions such as alpha-linolenic acid, linoleic acid, palmitic acid, palmitoleic acid, oleic acid.Green pepper mesh benevolence
Oil has antiallergy, anti-inflammatory, effect, and zanthoxylum oil external application, having improves skin abnormality symptom, moisturizing, makes skin slip comfortable.
Yuan roots：This product is also known as turnip, turnip, for the root tuber of crucifer turnip.It is cool in nature, sweet, micro-pungent.Have
Clearing heat and detoxicating, nourishing, the effect of anti-oxidant, beauty face-whitening-nourishing, smoothing wrinkle.
Sundew：This product is the whole herb with root of Droseraceae plant sundew.It is warm-natured, acrid flavour.With soft and moist skin, nourishing
Salubrity, enrich blood, kidney tonifying, clever and quick official's key, promoting blood circulation for regulating menstruation the effect of.
Edelweiss：This product is the aerial part of feverfew edelweiss.It is mild-natured, puckery.Stop with clearing heat and detoxicating, cool blood
Blood, antibacterial, oxidation resistant effect.
Fructus choerospondiatis：This product is the fruit of Anacardiaceae plant Spondias axillaris.It is mild-natured, it is sweet, sour.With heat-clearing, nourishing heart, calm the nerves, resist
The effect of oxidation.
Asiatic sweet leaf：This product is the leaf of Symplocaceae plant Asiatic sweet leaf.It is mild-natured, bitter.There is anti-inflammatory, clearing heat and detoxicating.
Above-mentioned five kinds of medicines belong to the common drug of Tibetan medicine, and the present invention is according to Tibetan medicine's classical works《Four doctor's allusion quotations》、《It is brilliant
Pearl book on Chinese herbal medicine》Record, with reference to Tibetan medicine and pharmacology traditional theory and above-mentioned five kinds of medicines in the situation of Tibet Popular Utilization, the side of being combined into.
Using advanced biotechnology, a kind of cleaning products of whitening spot-removing are made, it can be ensured that it dispels scar, the work of skin whitening
With without dry and astringent and excitement after use.
The present invention has advantages below：
(1) using grease based on babassu oil, highland barley bran, prinsepia utilis royle oil, mink oil, zanthoxylum oil, can have
Effect is solved using coconut oil and the skin caused by palm oil be dry and astringent, itch and excitement, moreover, good by prinsepia utilis royle oil
Penetration enhancing effect, the Tibetan medicine composition that can promote to be added in perfumed soap absorbed, and gives full play to its nti-freckle, skin whitening effect.
(2) present invention has been especially added with the extract solution of the Tibetan medicines such as Yuan roots, sundew, edelweiss, fructus choerospondiatis, Asiatic sweet leaf, is retaining
On the basis of perfumed soap cleaning skin, the effect of nti-freckle, whitening, conditioning skin may also function as.The present invention uses Traditional tibetan nationality medicine extract
Usage ratio pass through experiment screening, the effect of medicine can be given full play to.
(3) mild condition selected by preparation technology of the present invention, method are simple, and energy consumption is low, and without useless in preparation process
Water, waste gas produce, environmentally friendly.In addition, the preparation cost of this method is relatively low, it is adapted to large-scale production from now on to promote.
Embodiment
With reference to specific embodiment further illustrate the present invention technical solution, these embodiments it is not intended that
It is the limitation to technical scheme.
Embodiment 1
The preparation of Yuan root aqueous extracts：After Yuan roots crush, 40 mesh sieves are crossed, weigh 1Kg, extracting in water is twice：Add for the first time
10L water, boil extraction 2h；Second of addition 10L water, boils extraction 2h；Filtering, merge the decoction extracted twice, decoction
After 6000r/min centrifugations, heating is concentrated into 1L, obtains the Yuan root aqueous extracts that concentration is 1g/mL.
The preparation of sundew aqueous extract：After sundew crushes, 40 mesh sieves are crossed, weigh 1Kg, extracting in water is twice：First
Secondary addition 12L water, boil extraction 2h；Second of addition 10L water, boils extraction 2h；Filtering, merge the decoction extracted twice, medicine
After liquid 6000r/min centrifugations, heating is concentrated into 1L, obtains the sundew aqueous extract that concentration is 1g/mL.
The preparation of edelweiss ethanol extract：After edelweiss crushes, 40 mesh sieves are crossed, weigh 1Kg, add 70% alcohol reflux
Extraction is twice：The ethanol of 8L 70%, refluxing extraction 1.5h are added for the first time；Second of the addition ethanol of 6L 70%, refluxing extraction
1.5h；Filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, obtain the edelweiss ethanol that concentration is 1g/mL and extract
Liquid.
The preparation of fructus choerospondiatis ethanol extract：After fructus choerospondiatis crushes, 40 mesh sieves are crossed, weigh 1Kg, add the extraction of 60% alcohol reflux
Twice：The ethanol of 10L 60%, refluxing extraction 1.5h are added for the first time；Second of the addition ethanol of 8L 60%, refluxing extraction 1.0h；
Filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, obtain the fructus choerospondiatis ethanol extract that concentration is 1g/mL.
The preparation of Asiatic sweet leaf ethanol extract：After Asiatic sweet leaf crushes, 40 mesh sieves are crossed, weigh 1Kg, add the extraction of 70% alcohol reflux
Twice：The ethanol of 10L 70%, refluxing extraction 1.5h are added for the first time；Second of the addition ethanol of 6L 70%, refluxing extraction 1.0h；
Filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, obtain the Asiatic sweet leaf ethanol extract that concentration is 1g/mL.
The preparation process of freckle removing and whitening beauty soap is：
(1) 35Kg babassu oils, 10Kg zanthoxylum oils, 3Kg prinsepia utilis royle oils, 5Kg minks oil, 5Kg highland barley brans are weighed
Sequentially add in stainless steel cauldron, be heated with stirring to 50 DEG C, fully mix, and 50 DEG C of keeping temperature, it is standby；
(2) 20Kg deionized waters and 9Kg sodium hydroxides are weighed, sodium hydroxide is slowly added in water, side edged is with resistance to
Alkali agitator quickly stirs, and sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；
(3) aqueous slkali is slowly added in the miscella that step (1) mixes, side bevelling is quickly stirred with alkaline-resisting agitator
Mix, the mixed liquor to sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；
(4) 8Kg Yuan roots aqueous extract, 2Kg sundews aqueous extract, 1Kg edelweiss second are added while stirring in soap lye
Alcohol extract, 1Kg fructus choerospondiatis ethanol extract and 1Kg Asiatic sweet leaf ethanol extracts, stir 30 minutes, obtain mixing soap lye；
(5) mixing soap lye is poured into mould, cooling placement 48h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；
(6) after being stripped, product continues to be placed on aging 60 days at shady and cool ventilation, that is, obtains freckle removing and whitening beauty soap finished product.
Embodiment 2
Yuan roots aqueous extract, sundew aqueous extract, edelweiss ethanol extract, fructus choerospondiatis ethanol extract, Asiatic sweet leaf ethanol
Extract solution is the same as embodiment 1.
The preparation process of freckle removing and whitening beauty soap is：
(1) 20Kg babassu oils, 15Kg zanthoxylum oils, 8Kg prinsepia utilis royle oils, 5Kg minks oil, 5Kg highland barley brans are weighed
Sequentially add in stainless steel cauldron, be heated with stirring to 50 DEG C, fully mix, and 50 DEG C of keeping temperature, it is standby；
(2) 18Kg deionized waters and 6Kg sodium hydroxides are weighed, sodium hydroxide is slowly added in water, side edged is with resistance to
Alkali agitator quickly stirs, and sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；
(3) aqueous slkali is slowly added in the miscella that step (1) mixes, side bevelling is quickly stirred with alkaline-resisting agitator
Mix, the mixed liquor to sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；
(4) 8Kg Yuan roots aqueous extract, 6Kg sundews aqueous extract, 3Kg edelweiss second are added while stirring in soap lye
Alcohol extract, 3Kg fructus choerospondiatis ethanol extract and 3Kg Asiatic sweet leaf ethanol extracts, stir 60 minutes, obtain mixing soap lye；
(5) mixing soap lye is poured into mould, cooling placement 36h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；
(6) after being stripped, product continues to be placed on aging 30 days at shady and cool ventilation, that is, obtains freckle removing and whitening beauty soap finished product.
Embodiment 3
Yuan roots aqueous extract, sundew aqueous extract, edelweiss ethanol extract, fructus choerospondiatis ethanol extract, Asiatic sweet leaf ethanol
Extract solution is the same as embodiment 1.
The preparation process of freckle removing and whitening beauty soap is：
(1) 31Kg babassu oils, 13Kg zanthoxylum oils, 6Kg prinsepia utilis royle oils, 3.5Kg minks oil, 3.5Kg highland barley brans are weighed
Skin oil is sequentially added in stainless steel cauldron, is heated with stirring to 50 DEG C, is fully mixed, and 50 DEG C of keeping temperature, standby；
(2) 19Kg deionized waters and 8Kg sodium hydroxides are weighed, sodium hydroxide is slowly added in water, side edged is with resistance to
Alkali agitator quickly stirs, and sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；
(3) aqueous slkali is slowly added in the miscella that step (1) mixes, side bevelling is quickly stirred with alkaline-resisting agitator
Mix, the mixed liquor to sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；
(4) 6Kg Yuan roots aqueous extract, 4Kg sundews aqueous extract, 2Kg edelweiss second are added while stirring in soap lye
Alcohol extract, 2Kg fructus choerospondiatis ethanol extract and 2Kg Asiatic sweet leaf ethanol extracts, stir 45 minutes, obtain mixing soap lye；
(5) mixing soap lye is poured into mould, cooling placement 24h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；
(6) after being stripped, product continues to be placed on aging 45 days at shady and cool ventilation, that is, obtains freckle removing and whitening beauty soap finished product.
Embodiment 4
Yuan roots aqueous extract, sundew aqueous extract, edelweiss ethanol extract, fructus choerospondiatis ethanol extract, Asiatic sweet leaf ethanol
Extract solution is the same as embodiment 1.
The preparation process of freckle removing and whitening beauty soap is：
(1) 35Kg babassu oils, 12Kg zanthoxylum oils, 8Kg prinsepia utilis royle oils, 5Kg minks oil, 5Kg highland barley brans are weighed
Sequentially add in stainless steel cauldron, be heated with stirring to 50 DEG C, fully mix, and 50 DEG C of keeping temperature, it is standby；
(2) 19Kg deionized waters and 8Kg sodium hydroxides are weighed, sodium hydroxide is slowly added in water, side edged is with resistance to
Alkali agitator quickly stirs, and sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；
(3) aqueous slkali is slowly added in the miscella that step (1) mixes, side bevelling is quickly stirred with alkaline-resisting agitator
Mix, the mixed liquor to sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；
(4) 3Kg Yuan roots aqueous extract, 2Kg sundews aqueous extract, 1Kg edelweiss second are added while stirring in soap lye
Alcohol extract, 1Kg fructus choerospondiatis ethanol extract and 1Kg Asiatic sweet leaf ethanol extracts, stir 45 minutes, obtain mixing soap lye；
(5) mixing soap lye is poured into mould, cooling placement 48h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；
(6) after being stripped, product continues to be placed on aging 60 days at shady and cool ventilation, that is, obtains freckle removing and whitening beauty soap finished product.
Embodiment 5
Yuan roots aqueous extract, sundew aqueous extract, edelweiss ethanol extract, fructus choerospondiatis ethanol extract, Asiatic sweet leaf ethanol
Extract solution is the same as embodiment 1.
The preparation process of freckle removing and whitening beauty soap is：
(1) 25Kg babassu oils, 10Kg zanthoxylum oils, 8Kg prinsepia utilis royle oils, 5Kg minks oil, 5Kg highland barley brans are weighed
Sequentially add in stainless steel cauldron, be heated with stirring to 50 DEG C, fully mix, and 50 DEG C of keeping temperature, it is standby；
(2) 20Kg deionized waters and 9Kg sodium hydroxides are weighed, sodium hydroxide is slowly added in water, side edged is with resistance to
Alkali agitator quickly stirs, and sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；
(3) aqueous slkali is slowly added in the miscella that step (1) mixes, side bevelling is quickly stirred with alkaline-resisting agitator
Mix, the mixed liquor to sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；
(4) 8Kg Yuan roots aqueous extract, 6Kg sundews aqueous extract, 2Kg edelweiss second are added while stirring in soap lye
Alcohol extract, 1Kg fructus choerospondiatis ethanol extract and 1Kg Asiatic sweet leaf ethanol extracts, stir 45 minutes, obtain mixing soap lye；
(5) mixing soap lye is poured into mould, cooling placement 48h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；
(6) after being stripped, product continues to be placed on aging 30 days at shady and cool ventilation, that is, obtains freckle removing and whitening beauty soap finished product.
Embodiment 6
The product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4 are to TYR inhibition of enzyme activity
Experiment
The color of human skin derives from the outermost layer of skin, and melanocyte is located at epidermis and can produce melanin, and
The color of skin depends on content and the distribution of melanin.Tyrosine is the primary raw material for manufacturing melanin, and tyrosinase is junket
Propylhomoserin is changed into the major rate-limiting enzyme of melanin, and the active size of the enzyme decides the quantity that melanin is formed, current cosmetics
The whitening product overwhelming majority of in the market is based on tyrosinase inhibitor.In order to evaluate the freckle removing and whitening of freckle removing and whitening beauty soap
Effect, suppress TYR enzymatic activity to it and tested.
Materials and methods：
Sample：The product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4, commercially available freckle removing and whitening soap
Product, ursin (positive control).
Experimentation and result：
(1) preparation of phosphate buffer：Precision weighs Na2HPO412H2O 26.797g, NaH2PO42H2O
13.803g, respectively with after deionized water dissolving, it is settled in 500mL volumetric flasks.Take sodium dihydrogen phosphate and disodium phosphate soln
Each 100mL deionized water constant volume, shakes up into 500mL volumetric flasks, as pH=6.8 phosphate buffer.
(2) preparation of sample solution：Above-mentioned five kinds of samples are configured to concentration 0.1mg/mL, 0.2mg/ respectively with DMSO
ML, 0.3mg/mL, 0.4mg/mL, 0.5mg/mL, 0.6mg/mL, 0.7mg/mL, 0.8mg/mL testing sample solution.
(3) preparation of substrate TYR solution：Substrate TYR is configured to mass concentration with phosphate buffer
0.05% TYR solution.
(4) preparation of tyrosinase solution：Tyrosinase is configured to 100U/mL solution with phosphate buffer solution.
(5) measure of tyrosinase inhibition rate：Tetra- groups of C1, C2, T1, T2 except tyrosinase solution is accurately drawn by table 1
Sample liquid is reacted, after 37 DEG C of constant temperature water baths 10 minutes, tyrosinase solution is added, reacts 10 minutes, the reference using C2 as C1,
System absorbance A 1 at 475nm is measured, the reference using T2 as T1, measures system absorbance A 2.It is for what parallel sample was brought
System error, has been separately added into ImL DMSO in C1 and C2.To eliminate sample light absorbance error at 475nm, also add in T2
LmL sample solutions are entered.The inhibiting rate of tyrosinase is calculated by following equation, the results are shown in Table 2.
Wherein A1Not to be loaded the change of the absorbance of the reaction solution of product, A2For the absorbance of reaction solution after addition sample
The change of value.
The tyrosinase inhibition test reagent dosage table of table 1
Influence (%) of 2 beauty soap of the present invention of table to inhibitory activity against tyrosinase
As a result showing, three kinds of embodiment products of the invention have good inhibiting effect to tyrosinase activity, wherein, it is real
It is best to apply the inhibition of the formula of example 2, for concentration in 0.3mg/mL, its inhibiting rate reaches 52.33%, and embodiment 1 is formulated dense
For degree in 0.3mg/mL, its inhibiting rate is 50.30%, and in 0.4mg/mL, its inhibiting rate is the degree that embodiment 4 is formulated
56.78%, three kinds of Example formulations also accordingly increase with the increase of concentration, the inhibiting rate of tyrosinase, wherein, embodiment 1
Totally it is higher than embodiment 4 with the tyrosinase inhibition rate of embodiment 2；And the concentration of commercially available prod is when reaching 0.8mg/mL, it presses down
Rate processed is only 28.03%.As a result illustrate that three kinds of embodiment products are substantially better than commercially available prod to the inhibition of tyrosinase, three
Kind embodiment product is respectively provided with good freckle removing and whitening effect.
Embodiment 7
The product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the anti-oxidant experiment of the product of embodiment 4
(1) product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4 remove DPPH free radicals reality
Test
The product of sample freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4, commercially available freckle removing and whitening soap
Product, vitamin C (positive control).
Experimentation and result
Above-mentioned five kinds of samples are configured to absolute ethyl alcohol respectively concentration 0.05mg/mL, 0.06mg/mL, 0.07mg/mL,
0.08mg/mL, 0.09mg/mL, 0.1mg/mL, 0.2mg/mL, 0.3mg/mL, 0.4mg/mL, 0.5mg/mL testing sample solution.
2.5mL sample solutions are taken, the DPPH standard liquids that 2.5mL concentration is 50mg/L is added, mixes immediately, be put into darkroom at room temperature
30min is reacted, meanwhile, 2.5mL sample solutions are taken, 95% ethanol solution 2.5ml is added and is well mixed, the measure 517nm at
Absorbance.DPPH free radical scavenging activities are calculated by following equation, the results are shown in Table 3.
As：The absorbance for the mixed liquor that the sample solution of 2.5mlLDPPH solution and 2.5mL various concentrations forms；
A：For the test fluid and the absorbance of the mixed liquor of 2.5mL absolute ethyl alcohols composition of 2.5mL various concentrations；
A0：For the absorbance of 2.5mL DPPH solution and the mixed solution of 2.5mL absolute ethyl alcohols composition.
Influence (%) of 3 beauty soap of the present invention of table to DPPH free radical scavenging activities
(2) Prussia's blue laws determines the product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4 also
Proper energy power
Prussia's blue laws is using Prussian blue growing amount as index, utilizes the Fe in the potassium ferricyanide3+, when reducing power is strong
Material and Fe3+During reaction, Fe can be produced2+Become Prussian blue and Prussian blue growing amount, extinction are detected under 700nm wavelength
The reducing power of the higher expression tealeaves of degree is stronger, and antioxidant effect is better.
The product of sample freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4, commercially available freckle removing and whitening soap
Product, vitamin C (positive control).
Experimentation and result
By above-mentioned five kinds of samples with 95% ethanol be configured to respectively concentration 0.05mg/mL, 0.06mg/mL, 0.07mg/mL,
0.08mg/mL, 0.09mg/mL, 0.1mg/mL, 0.2mg/mL, 0.3mg/mL, 0.4mg/mL, 0.5mg/mL testing sample solution.
Precision draws the sample solution 1.0ml of series concentration, adds 2.5mL phosphate buffers (0.2molL-1, pH=6.6) and
2.5mL1% potassium ferricyanide solution, it is well mixed, mixed liquor is placed in 50 DEG C of water-baths after 20min and cooled down immediately, adds
10% solution of trichloroacetic acid 2.5mL, 10min is centrifuged in 3000r/min after mixing, take supernatant 2.5mL, add distilled water
The 2.5mL and ferric trichloride 0.5mL that mass fraction is 0.1%, is well mixed, places 4min, returned to zero with distilled water, measure reaction
Light absorption value A of the liquid at 700nm, 0.1% ferric trichloride is replaced with 0.5ml distilled water, determine the absorbance of blank control
A0.Reducing power=A-A0, wherein reducing power is bigger, and the oxidation resistance of sample is stronger.It the results are shown in Table 4.
The reducing power of 4 beauty soap of the present invention of table
(3) product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4 remove ABTS free radicals reality
Test
The product of sample freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4, commercially available freckle removing and whitening soap
Product, vitamin C (positive control).
Experimentation and result
By determining the absorbance of ABTS radical ions under 754nm, clearance rate of the evaluation sample to ABTS free radicals.Will
Above-mentioned five kinds of samples with 95% ethanol be configured to respectively concentration 0.05mg/mL, 0.06mg/mL, 0.07mg/mL, 0.08mg/mL,
0.09mg/mL, 0.1mg/mL, 0.2mg/mL, 0.3mg/mL, 0.4mg/mL, 0.5mg/mL testing sample solution.Precision measures
7mmol/L ABTS solution (is prepared) 0.20ml by distilled water, is mixed with 0.20ml 2.6mmol/L potassium persulfate solution,
40-50 times of dilution, makes the absorbance at solution 754nm be maintained at 0.7 ± 0.02, both obtains ABTS free radical working solutions, room temperature
Under be kept in dark place.4mlABTS is drawn respectively to be sufficiently mixed uniformly with 1ml Tea Samples, stands 6min, and sky is used as using 95% ethanol
Absorbance is determined at Bai Zhao, 754nm.Clearance rate is calculated according to the following formula：
Wherein, A0For the absorbance of ABTS free radicals in itself, A is sample to the absorbance after ABTS Free Radicals
Value.It the results are shown in Table 5.
Influence (%) of 5 beauty soap of the present invention of table to ABTS free radical scavenging activities
The different anti-oxidant experimental result of three of the above shows that three kinds of embodiment products of the invention have good antioxygen
Change acts on, and the size of antioxygenic property is：Embodiment 1 is formulated>Embodiment 2 is formulated>Embodiment 4 is formulated, three kinds of formulation products
Antioxygenic property is significantly better than that commercially available prod.In melanin forming process, oxygen radical has played initiation, and oxygen is certainly
The speed that melanin formed is accelerated by the presence of base, therefore, by scavenging activated oxygen, can effectively reduce the life of melanin
Into so as to reach skin whitening effect.The anti-oxidant description of test of the present embodiment, inventive formulation product can effectively remove oxygen freedom
Base, so as to play the effect of freckle removing and whitening.
Embodiment 8
The product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product human body whitening of embodiment 4 experiment
The product of sample freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4, commercially available freckle removing and whitening soap
Product.
Choose the voluntary people of trier 80 (people of male 40, the people of women 40, age 18-25 year), skin category normal condition, body
Situation is normal, no cosmetic allergic contact dermatitis history.Volunteer is divided into 4 groups, every group of 20 people, M-F half and half.First group, try out and implement
The product of example 1；Second group, try out the product of embodiment 2；3rd group, try out the product of embodiment 4；4th group, try out commercially available freckle removing and whitening
Soap product.Upside is tested in the arm of left and right, cleans test zone 2 times using product sooner or later daily, wherein, in left hand
Upside is cleaned using beauty soap in arm, makees blank control (being cleaned using clear water) with upside correspondence position in right arm, point
Not before on probation, try out 4 weeks, try out 8 weeks, try out 12 weeks, using dermal melanin and ferroheme tester (Mexameter
MX18, German CK electronics corporations) test position dermal melanin index on probation, to weighing 6 points of tests, test result takes left and right arms
Average value, practical effect is investigated by data.Meanwhile pass through questionnaire form, master of the investigation trier to used product
Evaluation, including nti-freckle, whitening effect are seen, is moistened, moisturizing, the index such as soil release performance and the dry and astringent, excitement of product.It the results are shown in Table 6
With table 7.
The trier's subjective assessment table of table 6
The trier's dermal melanin index of table 7
Note：Compared with blank right arm, * P<0.05, * * P<0.01；Compared with left arm being tested with commercially available prod,ΔP<0.05。
Table 6 is subjective assessment table of the trier to Evaluation product, and the result in table is shown, the embodiment of the present invention 1, embodiment
2 and the product of embodiment 4 there is preferable freckle removing and whitening and moist moisture-keeping function, particularly freckle removing and whitening effect is substantially better than commercially available
Product.Three kinds of embodiment products have a good soil release performance, and substantially without dry and astringent and excitement, and the excitement of commercially available prod compared with
By force, long-term use of skin has obvious sensation of dryness.
Table 7 is trier's dermal melanin index table, from experimental result as can be seen that the embodiment of the present invention 1, embodiment 2
After four weeks on probation, its melanin index is decreased obviously product, compared with blank right arm, there is significant difference (P<0.05),
And the product of embodiment 4 has pole significant difference (P<0.01)；After on probation 8 weeks, the product of the embodiment of the present invention 1, three realities are used
The trier of a product is applied, its melanin index continues to decline, and compared with blank right arm, there is pole significant difference (P<0.01),
And compared with commercially available prod, its melanin index, which reduces, significant difference (P<0.05)；After on probation 12 weeks, three embodiments
The trier of product, its melanin index still have pole significant difference (P compared with blank right arm<0.01), and and commercially available prod
Compare, its melanin index has significant difference (P<0.05).Above-mentioned experimental result explanation, three embodiment products of the invention are equal
There is the obvious melanin index that reduces to act on, its positive effect is better than commercially available prod, and the effect of its freckle removing and whitening is notable.
Embodiment 9
The product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product pH value of embodiment 4 measure
Take the product of freckle removing and whitening beauty soap embodiment 1, the product of embodiment 2, the product of embodiment 4 and commercially available whitening beauty soap
Each 1.0g of product, after 50mL deionized water dissolvings, pH value is determined with pH meter, the results are shown in Table 8.
The product pH value measurement result of table 8
PH value measurement result shows, the pH value of product of the embodiment of the present invention is between 7-8, relatively alkalescent, and commercially available
The pH value of product is 8.81, and alkalescence is stronger, illustrates that product pH value of the present invention is moderate, beneficial to protection skin.
The beauty soap of the present invention contains the Tibetan medicines such as Yuan roots, sundew, edelweiss, fructus choerospondiatis, Asiatic sweet leaf, in addition babassu oil, green grass or young crops
The good action of the base oils such as highland barley bran oil, prinsepia utilis royle oil, zanthoxylum oil, mink oil, there is the effect of obvious freckle removing and whitening, and
There is moist moisturizing, and in use, without dry and astringent, excitement.Using product of the present invention, flesh can be effectively maintained
Skin, skin effect are obvious.
Claims (1)
- A kind of 1. freckle removing and whitening beauty soap, it is characterised in that：By weight, its raw material includes：Babassu oil 20-35 parts, green pepper Mesh benevolence oil 10-15 parts, prinsepia utilis royle oil 3-8 parts, mink oil 2-5 parts, highland barley bran 2-5 parts, deionized water 15-20 parts, hydrogen-oxygen Change sodium 6-9 parts, Yuan root aqueous extract 3-8 parts, sundew aqueous extract 2-6 parts, edelweiss ethanol extract 1-3 parts, fructus choerospondiatis second Alcohol extract 1-3 parts, Asiatic sweet leaf ethanol extract 1-3 parts；A kind of freckle removing and whitening beauty soap, the preparation process of the freckle removing and whitening beauty soap are：(1) preparation method of Yuan roots aqueous extract is in the raw material components described in：After Yuan roots crush, 40 mesh sieves are crossed, weigh 1Kg, Extracting in water is twice：Add 10L water for the first time, boil extraction 2h, second of addition 10L water, boil extraction 2h, filter, merge two The decoction of secondary extraction, after decoction 6000r/min centrifugations, heating is concentrated into 1L, obtains the Yuan root aqueous extracts that concentration is 1g/mL；Institute Stating the preparation method of sundew aqueous extract in raw material components is：After sundew crushes, 40 mesh sieves are crossed, weigh 1Kg, extracting in water Twice：12L water is added for the first time, boils extraction 2h, and second of addition 10L water boils extraction 2h, filtering, and merging is extracted twice Decoction, decoction 6000r/min centrifugation after, heating be concentrated into 1L, obtain concentration be 1g/mL sundew aqueous extract；The original The preparation method of edelweiss ethanol extract is in material component：After edelweiss crushes, 40 mesh sieves are crossed, weigh 1Kg, add 70% second Alcohol reflux extracts twice：The ethanol of 8L 70%, refluxing extraction 1.5h, second of the addition ethanol of 6L 70%, backflow are added for the first time 1.5h is extracted, filtering, merges the decoction extracted twice, vacuum-concentrcted to 1L, obtains the edelweiss ethanol that concentration is 1g/mL and carry Take liquid；The preparation method of fructus choerospondiatis ethanol extract is in the raw material components：After fructus choerospondiatis crushes, 40 mesh sieves are crossed, 1Kg is weighed, adds Enter the extraction of 60% alcohol reflux twice：The ethanol of 10L 60%, refluxing extraction 1.5h, second of addition 8L 60% are added for the first time Ethanol, refluxing extraction 1.0h, filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, it is the wide of 1g/mL to obtain concentration Jujube ethanol extract；The preparation method of Asiatic sweet leaf ethanol extract is in the raw material components：After Asiatic sweet leaf crushes, 40 mesh sieves are crossed, are claimed 1Kg is taken, adds the extraction of 70% alcohol reflux twice：The ethanol of 10L 70%, refluxing extraction 1.5h, second of addition are added for the first time The ethanol of 6L 70%, refluxing extraction 1.0h, filtering, merge the decoction extracted twice, vacuum-concentrcted to 1L, it is 1g/ to obtain concentration ML Asiatic sweet leaf ethanol extract；(2) babassu oil, zanthoxylum oil, prinsepia utilis royle oil, mink oil, highland barley bran is taken to add successively by said components weight proportion Enter in stainless steel cauldron, be heated with stirring to 50 DEG C, fully mix, and 50 DEG C of keeping temperature, it is standby；(3) ionized water and sodium hydroxide are removed by said components weight proportion, sodium hydroxide is slowly added in water, side edged Quickly stirred with alkaline-resisting agitator, sodium hydroxide is cooled to 50 DEG C after being dissolved completely in water, obtains aqueous slkali；(4) aqueous slkali is slowly added in the miscella that step (2) mixes, side bevelling is quickly stirred with alkaline-resisting agitator, extremely The mixed liquor of sodium hydroxide solution and compound lard starts to occur thick, obtains thick soap lye；(5) Yuan roots aqueous extract, sundew aqueous extract, edelweiss ethanol extract, fructus choerospondiatis are added while stirring in soap lye Ethanol extract and Asiatic sweet leaf ethanol extract, 30-60 minutes are stirred, obtain mixing soap lye；(6) mixing soap lye is poured into mould, cooling placement 24-48h, the demoulding, obtains beauty soap under the conditions of 35 DEG C；(7) after being stripped, product continues to be placed on aging 30-60 days at shady and cool ventilation, that is, obtains freckle removing and whitening beauty soap finished product.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103540457A (en) * | 2013-10-18 | 2014-01-29 | 桂林雪芙莲日化有限公司 | Whitening and freckle-removing toilet soap |
| CN103589537A (en) * | 2013-11-19 | 2014-02-19 | 淮阴工学院 | Beautifying and antibacterial toilet soap |
| CN103725457A (en) * | 2013-12-16 | 2014-04-16 | 张圣坤 | Medical soap with supportive therapeutic efficacy to allergic dermatitis |
| CN104232375A (en) * | 2014-09-30 | 2014-12-24 | 郑通彪 | Skin care soap |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103540457A (en) * | 2013-10-18 | 2014-01-29 | 桂林雪芙莲日化有限公司 | Whitening and freckle-removing toilet soap |
| CN103589537A (en) * | 2013-11-19 | 2014-02-19 | 淮阴工学院 | Beautifying and antibacterial toilet soap |
| CN103725457A (en) * | 2013-12-16 | 2014-04-16 | 张圣坤 | Medical soap with supportive therapeutic efficacy to allergic dermatitis |
| CN104232375A (en) * | 2014-09-30 | 2014-12-24 | 郑通彪 | Skin care soap |
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Effective date of registration: 20191009 Address after: 450000 Suzhuang Village, Yingyang Town, Xiangcheng County, Xuchang City, Henan Province Patentee after: Li Shuang Feng Address before: 266000 Shandong province Qingdao City, Zhengzhou Road No. 53, Qingdao University of Science & Technology Patentee before: Qingdao University of Science & Technology |