CN105030911A - External traditional Chinese medicine composition with scalp blood circulation promoting and hair consolidating effects, preparation and method for preparing external traditional Chinese medicine composition - Google Patents

External traditional Chinese medicine composition with scalp blood circulation promoting and hair consolidating effects, preparation and method for preparing external traditional Chinese medicine composition Download PDF

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CN105030911A
CN105030911A CN201510406238.9A CN201510406238A CN105030911A CN 105030911 A CN105030911 A CN 105030911A CN 201510406238 A CN201510406238 A CN 201510406238A CN 105030911 A CN105030911 A CN 105030911A
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preparation
medicine composition
external
scalp
phase
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CN105030911B (en
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孟宏
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Beijing Guojizhongfang Institute Of Traditional Chinese Medicine
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Beijing Guojizhongfang Institute Of Traditional Chinese Medicine
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Abstract

The invention provides an external traditional Chinese medicine composition with a scalp blood circulation promoting and hair consolidating effects. The external traditional Chinese medicine composition comprises, by weight, 30-60 parts of tinospora sinensis merr, 20-60 parts of angelica sinensis, 10-20 parts of cactus, 10-20 parts of cloves and 10-20 parts of folium artemisiae argyi. The traditional Chinese medicine composition has the advantages that as proved by tests, extracts which are obtained by means of extraction after raw materials are combined with one another are safe and are free of irritation to the skins of the heads of users; scalp blood circulation improving and warming effects can be improved by the traditional Chinese medicine composition, and excellent hair consolidating effects can be realized; the raw materials are easily available, a method for preparing the external traditional Chinese medicine composition is simple and convenient, and the external traditional Chinese medicine composition is environmental friendly and safe, can be easily accepted by people and accordingly has excellent application and market prospects.

Description

There is the external medicine composition, preparation and preparation method thereof that promote scalp blood circulation and hair strengthening effect
Technical field
The present invention relates to a kind of external nursing compositions, specifically a kind of have the external scalp care Chinese medicine composition promoting scalp blood circulation and hair strengthening effect and the care formulations prepared by this skin care compositions.
Background technology
Scalp care product effective object is head skin.Healthy scalp does not have pruritus, the phenomenon such as greasy, dry, and scalp sebum secretion is moderate, can not block follicular orifice.And head skin is more slim, easily responsive, sebaceous gland density is relatively large, and sebum secretion is vigorous, has essence different from face or body skin skin quality.On market, skin nursing products are a lot, but but product for scalp care is rarely found, and the research for scalp health is also more rare.In addition people's scalp care consciousness is thin, and principal concern, on the health and nursing of hair, thus have ignored the importance of scalp health.
Scalp is also a part for skin, and it has the structure similar with facial skin, but scalp is more fragile than facial skin, more slim, and the thickness of scalp is approximately 1.476 millimeters, and on cheek, the thickness of skin is approximately 1.533 millimeters; Scalp also has more sebaceous gland, and according to statistics, the sebaceous gland density on scalp is approximately 144 ~ 192/square centimeter, and on forehead is approximately 52 ~ 79/square centimeter, and on cheek is approximately then 42 ~ 78/square centimeter.This that is, even the most fuel-displaced forehead in heel portion is compared, the sebaceous gland quantity of scalp also has its 2 times more than.Scalp will focus on nursing more, and scalp care product will the problem such as attentional sensitivity more.And the skin nursing products of commercially available routine also and be not suitable for special scalp skin quality.
At present, commercially available scalp care product mainly combines with the hair care product such as shampoo and hair conditioner, belong to rinse-off products, rinse-off products is limited at scalp residence time, and functional component addition is low, cause " scalp care product " that real effect cannot be played, also easily cause scalp tender subject.Winter, scalp nursing solution was the impact produced scalp according to winter climate change, adopted traditional Chinese medical science prescription to reach corresponding effect effect; Winter weather cold, sweat gland smegma amount is few; How in the winter time for scalp provides enough warmth sensations, can reach and promote the microcirculatory object of scalp blood and suitably supplement oils and fats, improving the symptom that scalp produces because of cold weather is the focus that those skilled in the art study.
Summary of the invention
Primary and foremost purpose of the present invention is to propose a kind of external medicine composition with promotion scalp blood circulation and hair strengthening effect.
Another object of the present invention is the preparation method proposing a kind of above-mentioned composition.
The third object of the present invention is to propose a kind of scalp care preparation prepared based on above-mentioned composition.
Invention thinking of the present invention is:
The present invention utilizes advanced biotechnology, in conjunction with the theory of Chinese medical science of Chinese tradition, Herba Lycopodii, Radix Angelicae Sinensis, Radix et Caulis Opuntiae Dillenii, Flos Caryophylli and Folium Artemisiae Argyi are effectively combined, form compound preparation, and it can be used as active component, be prepared into warm hair strengthening scalp care essence, make the effect of its tool warm promotion scalp blood circulation and hair strengthening, thus effectively can improve the scalp problems because winter severe cold weather causes.Described component brief introduction is as follows:
Herba Lycopodii: bitter in the mouth, cool in nature.Return Liver Channel.There is relaxing muscles and tendons and activating QI and blood in the collateral, effect of wind-expelling pain-stopping.Cure mainly rheumatic arthralgia, sciatica, lumbar muscle strain, traumatic injury.
Radix Angelicae Sinensis: nature and flavor are sweet, pungent, warm.Return liver, the heart, spleen channel.Have and enrich blood; Invigorate blood circulation; Menstruction regulating and pain relieving; Moisturize effect of laxation.
Radix et Caulis Opuntiae Dillenii: cold in nature is bitter in the mouth, puckery.Enter the heart, lung, stomach three warp.Have heat-clearing and toxic substances removing, relaxing muscles and tendons and activating QI and blood in the collateral, dissipating blood stasis for subsidence of swelling, intestinal detoxication, cooling blood and relieving pain, intestine moistening is stopped blooding, benefiting stomach and stopping pain, effect of antitussive.
Flos Caryophylli: warming middle-JIAO, warming the kidney, sending down the abnormal ascending QI.Control singultus, vomiting, regurgitation, dysentery, trusted subordinate's cold type of pain, mass beside the umbilicus, hernia, tinea disease.
Folium Artemisiae Argyi: nature and flavor are pungent, bitter, temperature.Return liver,spleen,kidney warp.For spitting blood, epistaxis, metrorrhagia, menorrhagia, vaginal bleeding during pregnancy hematochezia, few abdomen cold type of pain, coldness and unbalance in meridians, cold womb is infertile; External treatment skin pruritus.
For realizing object of the present invention, the present invention adopts following concrete technical scheme:
Have the external medicine composition promoting scalp blood circulation and hair strengthening effect, wherein, described compositions is made up of the crude drug of following weight parts proportioning:
Herba Lycopodii 30 ~ 60, Radix Angelicae Sinensis 20 ~ 60, Radix et Caulis Opuntiae Dillenii 10 ~ 20, Flos Caryophylli 10 ~ 20, Folium Artemisiae Argyi 10 ~ 20.
The better weight of each crude drug of described compositions is:
Herba Lycopodii 40 ~ 60, Radix Angelicae Sinensis 40 ~ 60, Radix et Caulis Opuntiae Dillenii 10 ~ 15, Flos Caryophylli 15 ~ 20, Folium Artemisiae Argyi 15 ~ 20.
A preparation method for above-mentioned external medicine composition, wherein, described method step is as follows:
(1) each crude drug is taken according to above-mentioned weight, mix homogeneously after pulverizing respectively;
(2) adding percent by volume is that 60% ~ 80% propylene glycol carries out supersound extraction, and Extracting temperature is 40 DEG C ~ 60 DEG C, and the time is 30 ~ 60min, and ultrasonic power is 300 ~ 500W;
(3) stop heating, filter after extracting solution step (2) prepared leaves standstill, then sucking filtration and get final product.
Described in described step (2), the w/v g/mL of crude drug and propylene glycol is 1:8 ~ 1:12.
Leave standstill 2 ~ 4 hours in described step (3), after 100 ~ 200 orders filter, kieselguhr filter cake sucking filtration, the vacuum of sucking filtration is 0.06 ~ 0.1MPa, collects filtrate and get final product.
Have the external scalp care extract promoting scalp blood circulation and hair strengthening effect, wherein, described extract is obtained by said method extraction.
The purposes of said extracted thing in preparation has the external scalp care preparation promoting scalp blood circulation and hair strengthening effect.
Have the external scalp care preparation promoting scalp blood circulation and hair strengthening effect, wherein, described preparation is made up of said extracted thing and skin care field customary adjuvant.
Have the external scalp care compositions promoting scalp blood circulation and hair strengthening effect, wherein, described compositions is by A phase, B phase and C phase composition, and described A phase, B phase and C phase are made up of the raw material of following weight percentage ratio:
A preparation method for above-mentioned scalp care compositions, wherein, described method comprises the steps:
(1) A phase: be evenly sprinkling upon in water by carbomer, be stirred to and dissolve completely, adds A phase surplus stock successively, stirs, be heated to 85 DEG C;
(2) when temperature drops to below 50 DEG C, add B phase raw material, stir;
(3) when temperature drops to below 45 DEG C, add described Chinese medicine extract and other raw materials of C phase, stir; When temperature drops to less than 40 DEG C, to obtain final product.
The preparation that above-mentioned raw materials and method prepare is scalp care essence.Different according to use approach, external scalp care compositions of the present invention obtains active extract after extracting, it also can be made into other external scalp care preparations, as shampoo, hair conditioner etc., but be not limited to above-mentioned dosage form, various different external preparation can be made according to known method in scalp care product industrial circle.
The preparation method of Chinese medicine composition of the present invention is not limited to of the present invention, and in this area, other conventional methods also can realize described effect, and the inventive method is the better preparation method of inventor's recommendation.The composition of scalp care essence of the present invention except extract is not customary adjuvant, is the optimum formula that inventor obtains through creative work, collaborative onset between each component of formula.
Essence recommendation method of the present invention is: after cleaning scalp every day, essence is coated on scalp, massages gently, treat that essence absorbs completely, without the need to again cleaning.
Beneficial outcomes of the present invention:
Confirm non-stimulated to head skin safe through extracting the extract obtained through experiment after raw material of the present invention is composite.Chinese medicine extract of the present invention has and improves scalp blood circulation and warm effect, and has good hair strengthening effect.Raw material of the present invention obtains easily, preparation method is easy, green safety, and the crowd that is easy to accepts, and has good application prospect and market prospect.
Detailed description of the invention
The present embodiment medical material used all can be bought from China Medicament Group Corp. and obtain, and meets Pharmacopoeia of People's Republic of China 2005 editions standards.Other raw materials all obtain by commercially available purchase, and the present invention uses the source of raw material in table 1, and the instrument title that the present invention is used and producer are as table 2.
Table 1 raw material sources
Table 2 instrument title and producer
Title Model Producer
Thermostat water bath HH·S1-M Chang'an, Beijing scientific instrument factory
High-speed multifunctional pulverizer JP-400B-8 Yongkang City nine grades of rank in the feudal regimes Trade Co., Ltd.
Intelligent temperature control heating stirrer SZCL Yu Hua Instrument Ltd. of Gongyi City
Ultrasound wave circulation extractor SCIENTZ-HF5000 Henan brother instrument and equipment company limited
Circulating water type vacuum pump SHB-Ⅲ Zhengzhou Greatwall Scientific Industrial & Trading Co., Ltd.
Analytical balance CP224S Sartorius
Warm tester 4K15 Sigma company
Rubber is combed Commercially available
The preparation of embodiment 1 scalp care Chinese medicine extract of the present invention
(1) according to following weight parts proportioning weighting raw materials;
Herba Lycopodii 60 grams, Radix Angelicae Sinensis 60 grams, Radix et Caulis Opuntiae Dillenii 15 grams, Flos Caryophylli 20 grams, Folium Artemisiae Argyi 20 grams, be crushed to 80 orders respectively, mix homogeneously obtains compositions;
(2) adding percent by volume in compositions is that 70% propylene glycol carries out supersound extraction, and Extracting temperature is 45 DEG C, and the time is 30min, and ultrasonic power is 500W, and the w/v g/mL of described crude drug and propylene glycol is 1:10;
(3) stop heating, extracting solution step (2) prepared leaves standstill 2 hours, and after 200 orders filter, kieselguhr filter cake sucking filtration supernatant, vacuum is 0.06MPa, collects sucking filtration liquid and get final product.
The preparation of embodiment 2 scalp care Chinese medicine extract of the present invention
(1) according to following weight parts proportioning weighting raw materials;
Herba Lycopodii 30 grams, Radix Angelicae Sinensis 40 grams, Radix et Caulis Opuntiae Dillenii 10 grams, Flos Caryophylli 15 grams, Folium Artemisiae Argyi 15 grams, be crushed to 100 orders respectively, mix homogeneously obtains compositions;
(2) adding percent by volume in compositions is that 80% propylene glycol carries out supersound extraction, and Extracting temperature is 60 DEG C, and the time is 60min, and ultrasonic power is 300W, and the w/v g/mL of described Chinese medicine composition and propylene glycol is 1:12;
(3) stop heating, extracting solution step (2) prepared leaves standstill 3 hours, and after 100 orders filter, kieselguhr filter cake sucking filtration supernatant, vacuum is 0.1MPa, collects sucking filtration liquid and get final product.
The preparation of embodiment 3 scalp care Chinese medicine extract of the present invention
(1) according to following weight parts proportioning weighting raw materials;
Herba Lycopodii 40 grams, Radix Angelicae Sinensis 20 grams, Radix et Caulis Opuntiae Dillenii 20 grams, Flos Caryophylli 10 grams, Folium Artemisiae Argyi 10 grams, be crushed to 60 orders respectively, mix homogeneously obtains compositions;
(2) adding percent by volume in compositions is that 60% propylene glycol carries out supersound extraction, and Extracting temperature is 40 DEG C, and the time is 40min, and ultrasonic power is 400W, and the w/v g/mL of described Chinese medicine composition and propylene glycol is 1:8;
(3) stop heating, extracting solution step (2) prepared leaves standstill 4 hours, and after 100 orders filter, kieselguhr filter cake sucking filtration supernatant, vacuum is 0.06MPa, collects sucking filtration liquid and get final product.
The preparation of embodiment 4 essence of the present invention
Raw material and proportioning (mass percent), in table 3:
Table 3
(1) A phase: carbomer is evenly sprinkling upon in water, rapid stirring, to dissolving completely, adds A phase surplus stock successively, stirs, be heated to 85 DEG C;
(2) when temperature drops to below 50 DEG C, add B phase raw material, stir;
(3) when temperature drops to below 45 DEG C, add embodiment 1 and prepare extract and other raw materials of C phase, stir; When temperature drops to less than 40 DEG C, to obtain final product.
The preparation of embodiment 5 essence of the present invention
Raw material and proportioning (mass percent), in table 4:
Table 4
(1) A phase: carbomer is evenly sprinkling upon in water, rapid stirring, to dissolving completely, adds A phase surplus stock successively, stirs, be heated to 85 DEG C;
(2) when temperature drops to below 50 DEG C, add B phase raw material, stir;
(3) when temperature drops to below 45 DEG C, add embodiment 2 and prepare extract and other raw materials of C phase, stir; When temperature drops to less than 40 DEG C, to obtain final product.
The preparation of embodiment 6 essence of the present invention
Raw material and proportioning (mass percent), in table 5:
Table 5
(1) A phase: carbomer is evenly sprinkling upon in water, rapid stirring, to dissolving completely, adds A phase surplus stock successively, stirs, be heated to 85 DEG C;
(2) when temperature drops to below 50 DEG C, add B phase raw material, stir;
(3) when temperature drops to below 45 DEG C, add embodiment 3 and prepare extract and other raw materials of C phase, stir; When temperature drops to less than 40 DEG C, to obtain final product.
Efficacy experiments of the present invention
One, blood circulation Efficacy experiments is improved
1, experimental principle
Containing thrombin in tissue, the height of the concentration of thrombin directly has influence on the rate of setting of blood, if blood coagulation speed is very fast, will form poor blood circulation, the phenomenon that nutrition can not effectively be transported.Adopt this invention of fibrinogen plate assay Trombin inhibiting experimental evaluation to the microcirculatory effect of improvement.
2, experiment content
Adopt Fibrinogen as substrate, Fibrinogen flat board is made into agarose and Fibrinogen, with thrombin standard product and add quantitative thrombin standard product and embodiment 1 and prepare extract and relax sample, diffusion reaction respectively on this flat board, calculates inspection product according to inspection product reacting hole precipitation loop diameter active.
3, interpretation of result
The reacting hole precipitation loop diameter adding thrombin standard product is 11mm.
The reacting hole precipitation loop diameter adding thrombin standard product and extract biased sample is 5mm
Suppression ratio=(thrombin diameter-mixture diameter)/thrombin diameter x100%
By calculating embodiment 1, to prepare extract for the suppression ratio of thrombin be 43.75%.Can find out that Chinese medicine extract has good inhibitory action for thrombin.Inventor utilizes embodiment 2,3 to prepare extract and repeats above-mentioned experiment, and result is with above-mentioned.
Two, warm efficacy study---human trial
1, experiment material
Experiment condition: random selecting 100 volunteers, men and women does not limit, and the age is not limit;
Given the test agent: embodiment 4 prepares scalp care essence 100, and 50g/ props up;
Tested time: winter, i.e. 12 ~ February;
2, experimental technique
Provide trial product to 100 volunteers, after having cleaned scalp every day, get appropriate amount of sample, be applied on scalp, be massaged into and absorb completely, fill in questionnaires according to practical situation.
3, interpretation of result
Statistics questionnaire investigation result, can feel after volunteer uses this product obviously sensation scalp have warmth sensation account for 35%, feel to have certain warmth sensation account for 53%, do not feel warmth sensation account for 12%.
Three, hair strengthening effect---human trial
1, experiment material
Experiment condition: select the age 25 one full year of life ~ 45 one full year of life, skin of head are healthy without irritated or scar and the hair loss patient 72 without local system other diseases, male 48, women 24.
Given the test agent: embodiment 4 prepares nursing essence 72,150 grams/;
Tested time: winter, i.e. 12 ~ February;
2, experimental technique
Volunteer is divided into two large groups, namely sample sets, blank group; Respectively comprise 24 male, 12 women in each large group, every large group is divided into six groups, every group Stochastic choice 6 people again.The situation tracking of health status sent out by advanced wardrobe, after allowing whole volunteer clean scalp at first 15 days according to personal habits, after hair natural air drying, combs logical hair 10 times every day, record number of at every turn shaving one's head, be aggregated into form with the Quercus acutissima Carr. comb provided.
Sample sets, according to personal habits, after cleaning scalp every day, gets appropriate essence, essence is smeared to scalp, be massaged into and absorb completely, without the need to again cleaning; Within 16th day, count in experiment beginning, volunteer every five days, was led to hair 10 times with Quercus acutissima Carr. comb comb, and was recorded number of at every turn shaving one's head, be aggregated into form after hair natural air drying.If will make a record in time when there is untoward reaction, and the carrying out of termination test.
Blank group, according to personal habits, after cleaning scalp every day, treats hair natural air drying, within the 16th day, counts in experiment beginning, and volunteer led to hair 10 times every five days with Quercus acutissima Carr. comb comb, recorded number of at every turn shaving one's head, was aggregated into form.
This experiment amounts to three months, the first step 15 days by a definite date, second step 45 days by a definite date; In this experiment, volunteer arbitrarily can not change shampoo, selects shampoo according to being accustomed to separately, until experiment terminates.
3, interpretation of result
Alopecia number before and after table 6 sample sets is on probation
Alopecia number before and after table 7 blank group is on probation
According to above table, use the embodiment of the present invention 4 to prepare the quantity that scalp care essence can reduce trier's alopecia, illustrate that this essence has hair strengthening effect.The essence that inventor utilizes embodiment 5,6 to prepare repeats above-mentioned experiment, and experimental result is with above-mentioned.
Four, human body patch experiment
1, test objective
Human experimentation, by particular experiment, crowd forms test population, and test subject makes to apply some make up and causes the probability of human body skin untoward reaction before and after (and cosmetic industry composition).
2, test material
Speckle examination device: Beijing North doctor management of investment company limited produces, circular, diameter 12mm.
Speckle examination thing: Example 4 prepares essence 0.025g.
3, Subject Population and the testing time
Effective experimenter amounts to 30 people, and concrete sex composition and age structure are determined at random (meets that 2007 " cosmetics health specifications " are included in, exclusion standard.
The test time started: December in 2014 02 day to 2014 on December 04.
4, experimental technique
(1), by subject enrollment Standard Selection subject, number is 30 examples.
(2), select qualified patch material, sample is put into speckle examination device (amount of samples is 0.020g ~ 0.025g), control wells is blank (declining any material).Sample and blank are all affixed on the bent side of forearm of experimenter, gently press with palm and make it to stick equably on skin, continue 24h.
(3), remove speckle examination device after interval 30min, until impression disappear after observe dermoreaction.
(4), after patch test 24h and 48h observes once respectively again, observes dermoreaction.
(5), skin adverse reaction grade scale is in table 8:
5, experimental result
The classification of table 8 skin adverse reaction
Table 9 takes out speckle examination device 0.5 hour observed result
Speckle examination device 24 hours observed results removed by table 10
Speckle examination device 48 hours observed results removed by table 11
Explain according to skin enclosed type patch test results: in 30 routine experimenters, occur that the number of 1 grade of skin adverse reaction is more than 5 examples, or the number of 2 grades of skin adverse reactions is more than 2 examples, or when there is any 1 example more than 3 grades or 3 grades skin adverse reactions, judge that tested material has untoward reaction to human body.
Skin enclosed type patch test results is in table 9,10 and 11, and result shows, and sample has no adverse reaction to human body skin.The product that inventor utilizes other embodiments to prepare repeats above-mentioned experiment, and experimental result is with above-mentioned.

Claims (10)

1. have the external medicine composition promoting scalp blood circulation and hair strengthening effect, it is characterized in that, described external medicine composition is made up of the crude drug of following weight parts proportioning:
Herba Lycopodii 30 ~ 60, Radix Angelicae Sinensis 20 ~ 60, Radix et Caulis Opuntiae Dillenii 10 ~ 20, Flos Caryophylli 10 ~ 20, Folium Artemisiae Argyi 10 ~ 20.
2. external medicine composition as claimed in claim 1, it is characterized in that, described external medicine composition is made up of the crude drug of following weight parts proportioning:
Herba Lycopodii 40 ~ 60, Radix Angelicae Sinensis 40 ~ 60, Radix et Caulis Opuntiae Dillenii 10 ~ 15, Flos Caryophylli 15 ~ 20, Folium Artemisiae Argyi 15 ~ 20.
3. a preparation method for external medicine composition described in claim 1 or 2, is characterized in that, described preparation method step is as follows:
(1) each crude drug is taken according to weight described in claim 1 or 2, mix homogeneously after pulverizing respectively;
(2) adding percent by volume is that 60% ~ 80% propylene glycol carries out supersound extraction, and Extracting temperature is 40 DEG C ~ 60 DEG C, and the time is 30 ~ 60min, and ultrasonic power is 300 ~ 500W;
(3) stop heating, filter after extracting solution step (2) prepared leaves standstill, then sucking filtration and get final product.
4. preparation method as claimed in claim 3, it is characterized in that, described in described step (2), the w/v g/mL of crude drug and propylene glycol is 1:8 ~ 1:12.
5. preparation method as claimed in claim 3, is characterized in that, leaves standstill 2 ~ 4 hours in described step (3), and after 100 ~ 200 orders filter, kieselguhr filter cake sucking filtration, the vacuum of sucking filtration is 0.06 ~ 0.1MPa, collects filtrate and get final product.
6. have the external scalp care extract promoting scalp blood circulation and hair strengthening effect, it is characterized in that, described external scalp care extract is extracted by preparation method described in any one in claim 3 to 5 and obtains.
7. the purposes of external scalp care extract described in claim 6 in preparation has the external scalp care preparation promoting scalp blood circulation and hair strengthening effect.
8. have the external scalp care preparation promoting scalp blood circulation and hair strengthening effect, it is characterized in that, described external scalp care preparation is made up of external scalp care extract described in claim 6 and skin care field customary adjuvant.
9. have the external scalp care compositions promoting scalp blood circulation and hair strengthening effect, it is characterized in that, described external scalp care compositions is by A phase, B phase and C phase composition, and described A phase, B phase and C phase are made up of the raw material of following weight percentage ratio:
10. a preparation method for external scalp care compositions described in claim 9, is characterized in that, described preparation method comprises the steps:
(1) A phase: be evenly sprinkling upon in water by carbomer, be stirred to and dissolve completely, adds A phase surplus stock successively, stirs, be heated to 85 DEG C;
(2) when temperature drops to below 50 DEG C, add B phase raw material, stir;
(3) when temperature drops to below 45 DEG C, add external scalp care extract described in claim 6 and other raw materials of C phase, stir; When temperature drops to less than 40 DEG C, to obtain final product.
CN201510406238.9A 2015-07-10 2015-07-10 With external medicine composition, preparation for promoting scalp blood circulation and strengthen the hair effect and preparation method thereof Active CN105030911B (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816718A (en) * 2016-04-27 2016-08-03 王沛 External traditional Chinese medicine composition with hair care and hair blackening effects

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584650A (en) * 2009-05-20 2009-11-25 姚宇妍 Pure natural shampoo and preparing method
CN102247308A (en) * 2011-06-14 2011-11-23 北京华夏众芳生物科技有限公司 Infiltration-promoting Chinese medicinal composition, preparation and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101584650A (en) * 2009-05-20 2009-11-25 姚宇妍 Pure natural shampoo and preparing method
CN102247308A (en) * 2011-06-14 2011-11-23 北京华夏众芳生物科技有限公司 Infiltration-promoting Chinese medicinal composition, preparation and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105816718A (en) * 2016-04-27 2016-08-03 王沛 External traditional Chinese medicine composition with hair care and hair blackening effects

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