CN105010829B - A kind of Health-care powder and its application method for preventing high yield cow postpartum hypocalcemia - Google Patents

A kind of Health-care powder and its application method for preventing high yield cow postpartum hypocalcemia Download PDF

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CN105010829B
CN105010829B CN201510366901.7A CN201510366901A CN105010829B CN 105010829 B CN105010829 B CN 105010829B CN 201510366901 A CN201510366901 A CN 201510366901A CN 105010829 B CN105010829 B CN 105010829B
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health
parts
care powder
postpartum
hypocalcemia
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CN105010829A (en
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徐闯
于洪江
陈媛媛
杨威
许秋实
沈泰钰
张子扬
朱奎玲
夏成
张洪友
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Heilongjiang Bayi Agricultural University
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Heilongjiang Bayi Agricultural University
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Abstract

The invention discloses a kind of Health-care powder and its application method for preventing high yield cow postpartum hypocalcemia.Described Health-care powder includes following component, and each component is by weight:120 parts of calcium citrate 110 part, 120 parts of magnesium chloride 110 part, 30 parts of yeast 25 part, 400 parts of brown sugar 390 part, 60 parts of sodium chloride 50 part.The Health-care powder of feeding of the present invention has easy to use, and cost is cheap, and palatability is good, the advantages that significant effect.Postpartum feeds the milk cow of this Health-care powder, can quickly regain one's strength, and maintains blood calcium concentration, recovers feed intake, improves the output of milk, strengthens resistance against diseases.Effectively reduce the incidence of disease of high yield cow postpartum Nutrition and Metabolism disease hypocalcemia.

Description

A kind of Health-care powder and its application method for preventing high yield cow postpartum hypocalcemia
Technical field
The invention belongs to livestock-raising field, and in particular to a kind of Health-care powder for preventing high yield cow postpartum hypocalcemia And its application method.
Technical background
Milk cow postpartum hypocalcemia is a kind of Nutrition and Metabolism disease that cow in perinatal period is often sent out, and milk cow health is influenceed tight Weight and secondary other diseases.In general, milk cow itself is in the state of calcium dynamic equilibrium, can be because when cow birth Appetite is relatively low and the factor such as a large amount of lactations, and causes hypocalcemia.Hypocalcemia can be divided into according to clinical symptoms are whether there is Clinical type hypocalcemia and Subclinical hypocalcemia.Clinical type hypocalcemia (total blood calcium concentration<1.4mmol/L, also known as breast Heat, take place mostly within postpartum 72h, be mainly shown as spiritual depressed, hypothermia, sleeping ground does not rise, or even dead.It is subclinical The low blood calcium of type (total blood calcium concentration is 1.4-2.0mmol/L), does not show clinical symptoms typically, therefore be clinically easy to be neglected Depending on being not easy the concern for causing manager and animal doctor.The low blood calcium of clinical type, whole lactation period output of milk meeting once occur for milk cow postpartum 1200~2000kg is lost, wherein the ox for having 13% can be eliminated, the also easy secondary other diseases of the disease, can be brought to pasture seriously Economic loss.Substantial amounts of experimental data and production practices prove, when hypocalcemia occurs for milk cow postpartum, give intravenous injection or Calcium preparation is gavaged, can effectively treat hypocalcemia.But treatment is gone to bring very big side effect to milk cow after falling ill again.To sum up Described, hypocalcemia is the milk cow postpartum normal property sent out disease, is just particularly important so preventing the disease.
The content of the invention
Technical problem, a kind of prevention high yield cow postpartum hypocalcemia provided by the present invention be present to solve background technology Health-care powder and its application method, the Health-care powder of the application can effectively maintain blood calcium (Ga), blood magnesium (Mg), serium inorganic phosphorus (P) and Glucose (GLU) is horizontal, reduces beta-hydroxybutyric acid (BHBA) level, reduces the generation of high yield cow postpartum hypocalcemia.Make high yield Milk cow postpartum quickly regains one's strength, and maintains cud Microflora, recovers feed intake, the output of milk is improved, so as to improve the warp in pasture Ji benefit.
Technical scheme is used by the application:Described Health-care powder includes following component, and each component is by weight: 110 parts -120 parts of calcium citrate, 110 parts -120 parts of magnesium chloride, 25 parts -30 parts of yeast, 390 parts -400 parts of brown sugar, sodium chloride 50 - 60 parts of part.
The application method of the Health-care powder of described prevention high yield cow postpartum hypocalcemia:Milk cow postpartum is by Health-care powder 710g~730g, uniformly it is mixed in 3-4kg postpartum conventional feeds, allows it to search for food, continuously feed 3d, once a day.
Described Health-care powder is applied to prevention high yield cow postpartum Nutrition and Metabolism disease hypocalcemia.
Beneficial effect is possessed by the application:Milk cow postpartum feed by calcium, raw sugared precursor, energy matter, mineral matter and This postpartum health care pulvis of Tiny ecosystem material composition prevents hypocalcemia, is a kind of effective method, also obtains in an experiment Checking.The core of this experiment is all of above demand to concentrate on a kind of solid powder product, with simple, efficient, peace Entirely, economic method goes to prevent milk cow postpartum hypocalcemia.Pulvis of the present invention in use every part usage amount be it is constant, The working link of live veterinarian can be reduced.This Health-care powder is concentrated in 730g weight, have it is easy to use, into This is cheap, and palatability is good, and the advantages that significant effect, this Health-care powder is a kind of health product of stabilization.
In addition, existing health product is to gavage liquid postpartum mostly, cow rumen intubation, which gavages, requires that operating personnel have Certain practice technology, if error will gavage perfusion and will occur because of foreign body in lung dead to tracheae or intrapulmonary, milk cow;And And postpartum gavages meeting and very big meet an urgent need is produced to milk cow.And the Health-care powder of the present invention is to feed, milk cow free choice feeding feed Health-care powder is eaten simultaneously, this can be avoided gavaging the adverse effect brought, and this Health-care powder is that independent packaging metering is constant, can It is current now to take without weighing, the labor intensity of veterinarian can be greatly reduced, reduce the work spending in pasture.
Embodiment
In order to further appreciate that the present invention feature and its effect, using following experimental verifications the present invention effect, in detail It is described as follows:
Health-care powder is by calcium citrate 120g, magnesium chloride 120g, yeast 30g, brown sugar 400g and chlorine used by this experiment Change sodium 60g to be mixed to prepare.
The application method of Health-care powder:Milk cow postpartum takes this Health-care powder 730g, is uniformly mixed in the routinely feeding of 3-4kg postpartum In material, it is allowed to search for food.3d continuously is fed, once a day.
1st, experimental animal
In certain intensive thousand pasture, according to principle similar in age, body condition, parity, select the expected date of childbirth close healthy Milk cow 16, wherein experimental group 7, control group 9;Experimental group control group milk cow antenatal postpartum according to NRC feeding standards just Often feeding.
2nd, experiment packet:
Experiment is divided into experimental group and control group, experimental group:0d, 1d and 2d after experimental group cow birth, continuous three days Health-care powder provided by the invention is fed daily at same time point, and the metering fed is the daily 730g/ heads of this product, control group milk Ox is without any processing.
3rd, sample collection
Experimental group and control group 0d, 1d, 2d, 3d, 7d, 14d, 21d after childbirth gather root of the tail venous blood 10ml, room Warm 3000rpm/min centrifugation 10min separation serum, -20 DEG C freeze it is to be checked.Wherein 0d, 1d, 2d are first to take a blood sample to feed afterwards.
4th, blood parameters detect:
Use semi-automatic biochemical analyzer detection blood calcium (Ga), blood magnesium (Mg), serium inorganic phosphorus (P), blood glucose (GLU) and beta-hydroxybutyric acid (BHBA) concentration.
5th, data processing:
Data analysis is carried out using spss19.0 data processing softwares, and counts the low blood of 16 experiment oxen in postpartum 21d The incidence of calcium.
Feed the influence horizontal to blood calcium in cow serum (Ga) of postpartum health care pulvis and be shown in Table 1:
The blood calcium of table 1 (Ga) (mean+SD) (unit:mmol/L)
Note:* (p<0.05) significant difference, * * (p are represented<0.01) represent that difference is extremely notable.In 2d, between group 3d and 21d significant differences, p value are respectively:P=0.010<0.05, p=0.02<0.05, p=0.017<0.05.
Feed the influence horizontal to serium inorganic phosphorus in cow serum (P) of postpartum health care pulvis and be shown in Table 2:
The serium inorganic phosphorus of table 2 (P) (mean+SD) (unit:mmol/L)
Note:* (p<0.05) significant difference, * * (p are represented<0.01) represent that difference is extremely notable.Indifference between the index group It is different.
Feed the influence horizontal to blood magnesium (Mg) in cow serum of postpartum health care pulvis and be shown in Table 3:
Table 3 blood magnesium (Mg) (mean+SD) (unit:mmol/L)
Note:* (p<0.05) significant difference, * * (p are represented<0.01) represent that difference is extremely notable.Although it is not present between group Difference, but experimental group 1d, 2d, 3d blood magnesium levels average value is higher than control group.
Feed the influence horizontal to blood glucose in cow serum (GLU) of postpartum health care pulvis and be shown in Table 4:
The blood glucose of table 4 (GLU) (mean+SD) (unit:mmol/L)
Note:* (p<0.05) significant difference, * * (p are represented<0.01) represent that difference is extremely notable.3d differences show between group Write, p=0.033<0.05. 1d, 2d blood sugar concentration for feeding this Health-care powder are higher than control group 1d, 2d blood sugar concentration.
Feed the influence horizontal to beta-hydroxybutyric acid in cow serum of postpartum health care pulvis and be shown in Table 5:
Table 5 beta-hydroxybutyric acid index (BHBA) (mean+SD) (unit:mmol/L)
Note:* (p<0.05) significant difference, * * (p are represented<0.01) represent that difference is extremely notable.Although it is not present between group Difference, but easily elevated 7d, 14d, 21d experimental group beta-hydroxybutyric acid concentration is dense less than control group beta-hydroxybutyric acid in beta-hydroxybutyric acid Degree.
The low blood calcium morbidity statistics of experimental group, control group is shown in Table 6:
The low blood calcium incidence of disease of table 6
Data analysis experimental group milk cow blood calcium concentration is can be seen that in 2d, 3d and 21d from data above analysis result Have differences and significant difference.Show that the Health-care powder can improve blood calcium concentration in a short time, again with long period regulation blood calcium Effect.It is short-term to improve blood calcium concentration, Postpartum Cows milk heat, the diseases such as syndrome of can not acting as a planted agent can be prevented;Long-term regulating and controlling blood sugar Concentration can improve milk cow production performance and health status.There is also the difference of conspicuousness in 3d for blood sugar concentration;Illustrate the guarantor Strong pulvis has the function that the energy supply of postpartum complementary energy makes Postpartum Cows quickly regain one's strength simultaneously.Morbidity statistics result can be seen Go out, the low blood calcium incidence of disease of experimental group is significantly lower than control group.In summary, Health-care powder of the invention has preferably prevention milk The effect of ox postpartum hypocalcemia.

Claims (1)

1. a kind of Health-care powder for preventing high yield cow postpartum hypocalcemia, described Health-care powder are made up of following ingredients, Each component is by weight:110 parts -120 parts of calcium citrate, 110 parts -120 parts of magnesium chloride, 25 parts -30 parts of yeast, brown sugar 390 Part -400 parts, 50 parts -60 parts of sodium chloride, feed Health-care powder 2.9804 ± 0.4472mmol/L of blood calcium after 3 days;Low blood calcium morbidity Rate 28.57%.
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CN106071173A (en) * 2016-08-22 2016-11-09 河南金百合生物科技股份有限公司 A kind of feed additive for milch cow postpartum recovery and preparation method thereof
CN111758845A (en) * 2020-08-11 2020-10-13 黑龙江八一农垦大学 Cow health-care granules in early lactation period and preparation method thereof

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US4185093A (en) * 1977-07-14 1980-01-22 Carnes Allen R Preparation and method for treatment of hypocalcemia, hypophosphatemia and downer cow syndrome in animals
CN101516210A (en) * 2006-09-14 2009-08-26 帝斯曼知识产权资产管理有限公司 Food supplementation composition containing one or more vitamin D3 compounds and one or more magnesium salts
CN102150756A (en) * 2010-12-13 2011-08-17 刘福元 Health-care premix for pre-perinatal high-yield milk cows
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CN101516210A (en) * 2006-09-14 2009-08-26 帝斯曼知识产权资产管理有限公司 Food supplementation composition containing one or more vitamin D3 compounds and one or more magnesium salts
CN102150756A (en) * 2010-12-13 2011-08-17 刘福元 Health-care premix for pre-perinatal high-yield milk cows
CN102326680A (en) * 2011-07-01 2012-01-25 上海光明荷斯坦牧业有限公司 Dairy cow postpartum nutrition enhancer premix and preparation method and application thereof

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