CN105010350A - Disinfectant highly efficient in sterilization and preparation method therefor - Google Patents

Disinfectant highly efficient in sterilization and preparation method therefor Download PDF

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Publication number
CN105010350A
CN105010350A CN201510323236.3A CN201510323236A CN105010350A CN 105010350 A CN105010350 A CN 105010350A CN 201510323236 A CN201510323236 A CN 201510323236A CN 105010350 A CN105010350 A CN 105010350A
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China
Prior art keywords
disinfectant
uniformly mixed
fully
preparation
ethanol
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CN201510323236.3A
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Chinese (zh)
Inventor
雷春生
张帆
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Changzhou University
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Changzhou University
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Priority to CN201510323236.3A priority Critical patent/CN105010350A/en
Publication of CN105010350A publication Critical patent/CN105010350A/en
Pending legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a disinfectant highly efficient in sterilization and a preparation method therefor, and belongs to the medical and health fields. The present invention adopts the following process steps: first inputting sodium dichloroisocyanurate, deionized water, ethanol,and sodium alginate in a container; stirring and mixing the materials; making the materials react at high temperature and a pressure; and then adding a surfactant glyceryl monostearate for purifying to acquire an efficient disinfectant. According to the study and the feedback of results of examples, medicament components of the disinfectant are qualified. The disinfectant has no strong odor and does not harm the skin of the human body, and the disinfection rate is very high, greater than 99.9%.

Description

A kind of efficient degerming disinfectant and preparation method thereof
Technical field
The present invention relates to a kind of efficient degerming disinfectant and preparation method thereof, belong to medicine and hygiene fields.
Background technology
Disinfectant refers to for killing pathogenic microorganism on communication media, make it reach the preparation of innoxious requirement, it is different from antibiotic, and its Main Function in diseases prevention eliminates outside human body by pathogenic microorganism, cut off the route of transmission of infectious disease, reach the object controlling infectious disease.People also often claim disinfectant to be " chemosterilant ".
Disinfectant can be divided into bactericidal agent, high effect disinfectants, middle effect disinfectants, low effect disinfectants according to its level acted on; Bactericidal agent can kill all microorganisms makes it reach sterilizing requirement, comprises formaldehyde, glutaraldehyde etc.; High effect disinfectants can kill all bacterial propagules, virus, fungi and spore thereof etc., has high-effective disinfecting level.
Have in life and there is a lot of bacteriums, comprise fungi, germ etc.; Can be described as ubiquitous, especially the bacterium infected when contacting thing is especially many, particularly in hospital, if medical personnel are less than the sterilization that carries out disinfection to its hand, bring a lot of disease risks so can to oneself and others, so carry out effective sterilization to have great necessity for the prevention of disease, the safety of self and the infection event of hospital.
The method that modern technologies carry out disinfection mainly contains two kinds, is respectively soap flowing and washes one's hands and chemosterilant sterilization.The soap flowing method of washing one's hands refers to and utilizes soap to clean hand, because human body skin is weakly acidic when cleaning, the washing agent of alkalescence can stimulate hand skin, and after thus alkaline soap uses, hand is easily dry, even peels; On the other hand, can not decontamination, disinfecting power is also very weak, for parasite and virus effectiveness poor, degerming rate is low-down; For skin sensitivity or have the people of wound be not suitable for use, with rear skin can become very dry.Other chemosterilant sterilization utilizes chemical agent to carry out disinfection, such as quaternary ammonium disinfectant, iodine class disinfectant, chloride class disinfectant; These disinfectants are corrosive usually, and smell is very strong, and the injury for skin is also very large, and sterilizing rate is also very general.
Summary of the invention
The technical problem that the present invention mainly solves: have strong smell for current disinfectant, the problem larger, sterilization rate is lower is injured to human body skin in disinfecting process, provide a kind of efficient degerming disinfectant and preparation method thereof, make mutually to react between it by adding various sterilization chemical agent, in addition using glycerin monostearate as surfactant, thus become effective disinfectant, this disinfectant improves sterilization rate, does not have strong smell, to human body skin without any injury.
In order to solve the problems of the technologies described above, the technical solution adopted in the present invention is:
(1) by mass percentage, get that 10% ~ 35% DCCA is received, to be positioned over volume be in the glass container of 5L for 40% ~ 60% deionized water, 5% ~ 10% ethanol, 10% ~ 25% sodium alginate, stir 10 ~ 15min by stirring rod, make it fully be uniformly mixed;
(2) mixture in the container after being fully uniformly mixed being positioned over temperature is 55 DEG C ~ 75 DEG C, and pressure is react 3 ~ 5h under the condition of 0.2MPa ~ 0.3MPa;
(3) add with said mixture mass ratio in mixture to be after the reaction the glycerin monostearate of 2% ~ 5%, to be fully uniformly mixed 3 ~ 5min by stirring rod, at temperature 55 DEG C ~ 75 DEG C, continue reaction, make it fully be uniformly mixed;
(4) after reacting 2 ~ 3 hours, obtain a kind of efficient degerming disinfectant of the present invention.
Further, in described disinfectant desirable 15% ~ 30% DCCA of each material receive, 45% ~ 55% deionized water, 7% ~ 8% ethanol, 15% ~ 20% sodium alginate.
Further, in described disinfectant desirable 20% ~ 25% DCCA of each material receive, 47% ~ 53% deionized water, 7.2% ~ 7.8% ethanol, 17% ~ 18% sodium alginate.
In the middle of component of the present invention, DCCA is received, ethanol is all the effect with sterilization, sterilizing, especially receive can the various invasive organism such as powerful kill bacteria gemma, bacterial propagule, fungi for DCCA, use glycerin monostearate as surfactant in addition, enhance the activity on permeability and surface, improve the ability of sterilization, thus fast and effeciently kill virus and relevant bacterium.
The invention has the beneficial effects as follows:
(1) irritant smell is not had, for human body skin without any injury, gentleer;
(2) Comparison of effect on sterilization is good, and degerming rate is higher, can effectively suppress various fungi;
(3) production cost is lower, and manufacture craft is fairly simple.
Embodiment
By mass percentage, get that 10% ~ 35% DCCA is received, to be positioned over volume be in the glass container of 5L for 40% ~ 60% deionized water, 5% ~ 10% ethanol, 10% ~ 25% sodium alginate, stir 10 ~ 15min by stirring rod, make it fully be uniformly mixed; It is 55 DEG C ~ 75 DEG C that mixture in container after being fully uniformly mixed is positioned over temperature, and pressure is react 3 ~ 5h under the condition of 0.2MPa ~ 0.3MPa; Adding with said mixture mass ratio in mixture is after the reaction the glycerin monostearate of 2% ~ 5%, is fully uniformly mixed 3 ~ 5min by stirring rod, proceeds dynamic chemical bond, make it fully be uniformly mixed at temperature 55 DEG C ~ 75 DEG C; A kind of efficient degerming disinfectant of the present invention is obtained after reacting 2 ~ 3 hours.
Further, in described disinfectant desirable 15% ~ 30% DCCA of material receive, 45% ~ 55% deionized water, 7% ~ 8% ethanol, 15% ~ 20% sodium alginate.
Further again, in described disinfectant desirable 20% ~ 25% DCCA of material receive, 47% ~ 53% deionized water, 7.2% ~ 7.8% ethanol, 17% ~ 18% sodium alginate.
Example 1
First by mass percentage, get that 10% DCCA is received, to be positioned over volume be in the glass container of 5L for 60% deionized water, 10% ethanol, 20% sodium alginate, stir 10min by stirring rod, make it fully be uniformly mixed; Then the mixture in the container after being fully uniformly mixed being positioned over temperature is 55 DEG C, and pressure is react 3h under the condition of 0.2MPa; Add with said mixture mass ratio in following mixture to be after the reaction the glycerin monostearate of 2%, to be fully uniformly mixed 3min by stirring rod, at temperature 55 DEG C, proceed dynamic chemical bond, make it fully be uniformly mixed; Eventually pass reaction and after 2 hours, obtain a kind of efficient degerming disinfectant of the present invention.
A kind of efficient degerming disinfectant finally obtained in this example does not have strong smell, and do not injure human body, degerming rate is up to 99.97%.
Example 2
First in percentage terms, get that 20% DCCA is received, to be positioned over volume be in the glass container of 5L for 52% deionized water, 8% ethanol, 15% sodium alginate, stir 13min by stirring rod, make it fully be uniformly mixed; Then the mixture in the container after being fully uniformly mixed being positioned over temperature is 65 DEG C, and pressure is react 4h under the condition of 0.25MPa; Add with said mixture mass ratio in following mixture to be after the reaction the glycerin monostearate of 2%, to be fully uniformly mixed 4min by stirring rod, at temperature 65 DEG C, proceed dynamic chemical bond, make it fully be uniformly mixed; Eventually pass reaction and after 2.5 hours, obtain a kind of efficient degerming disinfectant of the present invention.
A kind of efficient degerming disinfectant finally obtained in this example does not have strong smell, and do not injure human body, degerming rate is up to 99.98%.
Example 3
First in percentage terms, get that 15% DCCA is received, to be positioned over volume be in the glass container of 5L for 60% deionized water, 7% ethanol, 18% sodium alginate, stir 15min by stirring rod, make it fully be uniformly mixed; Then the mixture in the container after being fully uniformly mixed being positioned over temperature is 75 DEG C, and pressure is react 5h under the condition of 0.3MPa; Add with said mixture mass ratio in following mixture to be after the reaction the glycerin monostearate of 2%, to be fully uniformly mixed 5min by stirring rod, at temperature 75 DEG C, proceed dynamic chemical bond, make it fully be uniformly mixed; Eventually pass reaction and after 3 hours, obtain a kind of efficient degerming disinfectant of the present invention.
A kind of efficient degerming disinfectant finally obtained in this example does not have strong smell, and do not injure human body, degerming rate is up to 99.99%.

Claims (3)

1. an efficient degerming disinfectant preparation method, is characterized in that:
(1) by mass percentage, get that 10% ~ 35% DCCA is received, to be positioned over volume be in the glass container of 5L for 40% ~ 60% deionized water, 5% ~ 10% ethanol, 10% ~ 25% sodium alginate, stir 10 ~ 15min by stirring rod, make it fully be uniformly mixed;
(2) mixture in the container after being fully uniformly mixed being positioned over temperature is 55 DEG C ~ 75 DEG C, and pressure is react 3 ~ 5h under the condition of 0.2MPa ~ 0.3MPa;
(3) add with said mixture mass ratio in mixture to be after the reaction the glycerin monostearate of 2% ~ 5%, to be fully uniformly mixed 3 ~ 5min by stirring rod, at temperature 55 DEG C ~ 75 DEG C, continue reaction, make it fully be uniformly mixed;
(4) a kind of efficient degerming disinfectant of the present invention can be obtained after reacting 2 ~ 3 hours.
2. the efficient degerming disinfectant preparation method of the one according to claims 1, is characterized in that: in described disinfectant each material further desirable 15% ~ 30% DCCA receive, 45% ~ 55% deionized water, 7% ~ 8% ethanol, 15% ~ 20% sodium alginate.
3. efficient degerming disinfectant of the one according to claims 1 and preparation method thereof, is characterized in that: in described disinfectant each material more further desirable 20% ~ 25% DCCA receive, 47% ~ 53% deionized water, 7.2% ~ 7.8% ethanol, 17% ~ 18% sodium alginate.
CN201510323236.3A 2015-06-13 2015-06-13 Disinfectant highly efficient in sterilization and preparation method therefor Pending CN105010350A (en)

Priority Applications (1)

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CN201510323236.3A CN105010350A (en) 2015-06-13 2015-06-13 Disinfectant highly efficient in sterilization and preparation method therefor

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Application Number Priority Date Filing Date Title
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220089A (en) * 1998-11-19 1999-06-23 石强 Fast composite disinfectant
WO2008040884A2 (en) * 2006-10-05 2008-04-10 Eurotab Two-layer compacted solid product for water potabilization and preparation method
CN103655263A (en) * 2013-11-19 2014-03-26 青岛汇而通商贸有限公司 Efficient decontamination hand sanitizer
CN104322500A (en) * 2014-09-18 2015-02-04 青岛市高科专利技术转移平台有限公司 Medical disinfectant fluid

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220089A (en) * 1998-11-19 1999-06-23 石强 Fast composite disinfectant
WO2008040884A2 (en) * 2006-10-05 2008-04-10 Eurotab Two-layer compacted solid product for water potabilization and preparation method
CN103655263A (en) * 2013-11-19 2014-03-26 青岛汇而通商贸有限公司 Efficient decontamination hand sanitizer
CN104322500A (en) * 2014-09-18 2015-02-04 青岛市高科专利技术转移平台有限公司 Medical disinfectant fluid

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