CN105004576B - Sampling sample-adding all-in-one - Google Patents
Sampling sample-adding all-in-one Download PDFInfo
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- CN105004576B CN105004576B CN201510466722.0A CN201510466722A CN105004576B CN 105004576 B CN105004576 B CN 105004576B CN 201510466722 A CN201510466722 A CN 201510466722A CN 105004576 B CN105004576 B CN 105004576B
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Abstract
The invention discloses one kind to sample sample-adding all-in-one, including supporting mechanism, some sample loading guns, be provided with the supporting mechanism for drive the transversal driving mechanism of sample loading gun transverse shifting, the vertically movable mechanism for sample loading gun vertical shift, for sample-adding sampling is controlled sampling sample-adding controlling organization, for abandon pipette tips abandon pipette tips mechanism；The one kind of the invention that provides ensure that sampling and sample-adding process are pollution-free, efficient, fast and accurately sampling is loaded all-in-one.
Description
Technical field
The invention belongs to detection technique field, is related to a kind of sampling loading device, is sampled more particularly, to a kind of microorganism
It is loaded all-in-one.
Background technology
Sample loading gun is the instrument for functions such as sample precision liquid relief, reagent dilutions, distribution, mixings, can be used for hospital
Diagnostic test room, disease control laboratory, Life Science Laboratory, judicial expertise laboratory etc..Existing sample loading gun is generally single
Passage simple function.Need to use the device that this is a kind of similar to sample loading gun in detection process, first dilute sample or sample
Liquid takes out from container, is added to according to a certain amount in detection device, to avoid cross pollution, often finishes one-time detection, finally
Used pipette tips will be discarded in waste liquid tank.The difference of detection project and testing goal makes testing staff need to enter several times
Repeating for row sampling sample-adding, it is such to repeat, make detection accuracy, assay reproducibility and the efficiency of detection all
It cannot get effective guarantee and raising.
The content of the invention
The technical problem to be solved in the present invention is, for drawbacks described above of the prior art, there is provided one kind, which ensure that, to be taken
Sample and sample-adding process are pollution-free, efficient, fast and accurately sampling is loaded all-in-one.
The technical solution adopted for the present invention to solve the technical problems is：
Construct the first technical scheme：One kind sampling sample-adding all-in-one, including supporting mechanism, some sample loading guns, the branch
Multiple transversal driving mechanisms, vertically movable mechanism are provided with support mechanism, sample-adding controlling organization is sampled, abandons pipette tips mechanism；It is described
Supporting mechanism includes the support bar being vertically arranged, and rotating disk is rotatably connected on the support bar, the rotating disk is around support
Bar rotates；The vertically movable mechanism includes vertical guide pillar, vertically movable drive component, and the vertically movable drive component is set
Put in rotating disk or/and guide pillar, the vertically movable drive component drives the guide pillar to move up and down and position；The transverse direction
Drive mechanism is connected with guide pillar and the scattering device centered on guide pillar, transversal driving mechanism connection sample loading gun, drives sample loading gun horizontal
Scattered to the contraction of guide pillar direction or away from guide pillar；The sampling sample-adding controlling organization includes the sample-adding pressure on the sample loading gun of setting
The sample-adding drive component that head, the sample-adding sampling connector, the driving sample-adding control piece that drive sample-adding pressure head to move up and down move up and down；
The pipette tips mechanism that abandons includes being sleeved on the top-pressure part for being used for top pressure pipette tips outside sample loading gun, drives abandoning of moving up and down of top-pressure part
Pipette tips drive component.
In described sampling sample-adding all-in-one, the vertically movable drive component includes the drive rod being vertically arranged and driven
The vertical drive connection part that lever connects with guide pillar, the drive rod are driven on guide pillar up and down through vertical drive connection part
Lower movement；
Or the rotating disk is provided with mounting hole, the guide pillar gap coordinates in mounting hole and moved up and down, described perpendicular
The second keeper that straight motion drive component includes setting the first keeper on the rotating pan, is arranged on guide pillar, described the
Two keeper in the vertical directions are arranged at intervals at least two, first keeper and the second keeper clamping, grafting or button
It is connected together and positions guide pillar, and the first keeper and the second keeper is mutually disengaged releasing positioning under external force.
In described sampling sample-adding all-in-one, the vertical drive connection part is to be separately positioned on guide pillar and drive rod
Gear and rack.
In described sampling sample-adding all-in-one, transversal driving mechanism includes multiple transversal stretching bars laterally set, described
Transversal stretching bar scattering device centered on guide pillar is multiple and one end of each transversal stretching bar is fixed on guide pillar, each
The other end of transversal stretching bar is all connected with sample loading gun, and the outermost of the transversal stretching bar is provided with for controlling transversal stretching
The extension and contraction control component of bar transversal stretching.
In described sampling sample-adding all-in-one, control panel that the extension and contraction control component includes being rotatably connected on guide pillar,
For fixing sample loading gun fixture, the sliding block being fixedly connected with sample loading gun fixture of each sample loading gun；Opened in the control panel
Have multiple arcs control flume, each sliding block be inserted into corresponding in the arc control flume, the sample loading gun fixture with
Transversal stretching bar is fixedly connected, and is rotated control panel and is caused sliding block slides in arc control flume to drive sample loading gun to guide pillar contraction or remote
From guide pillar.
Described sampling sample-adding all-in-one, the shape of the arc control flume and position meet：Sliding block is in arc control flume
Sample loading gun transverse direction straight line is driven to be contracted to guide pillar direction or away from guide pillar during middle slip.
Described sampling sample-adding all-in-one, one end of the sample-adding sampling connector are sleeved under sample-adding sampling drive component
Side guide pillar on, the other end be loaded pressure head be fixedly connected；The sample-adding that the sample-adding drive component includes being fixed on guide pillar is convex
Wheel mechanism, the sample-adding control-rod being vertically arranged along guide pillar；The sample-adding cam mechanism top pressure adds at the top of sample-adding sampling connector
Sample cam mechanism rotation driving sample-adding sampling connector moves up and down.
Described sampling sample-adding all-in-one, the sample-adding cam mechanism include being sleeved on guide pillar and intermeshing up and down
First cam and the second cam, first cam and the second cam are respectively tubular, and the two end face being in contact all is tooth form
Or waveform；First cam is connected with sample-adding control-rod and rotated by being loaded control-rod control, the second cam top
It is pressed at the top of sample-adding sampling connector.
Described sampling sample-adding all-in-one, the sample loading gun include being used to contain the sample-adding cylinder of sample, for drawing sample
Product or the sample-adding push rod for pushing sample, sample-adding push rod are inserted into sample-adding cylinder.
Described sampling sample-adding all-in-one, the pipette tips drive component of abandoning include being fixed on guide pillar abandoning pipette tips cam machine
Structure, with abandoning abandoning pipette tips connector, being vertically arranged along guide pillar and be connected with abandoning pipette tips cam mechanism for pipette tips cam mechanism cooperation
Abandon pipette tips control-rod, the top pressure return unit resetted upwards for top-pressure part, it is described abandon pipette tips connector one end and be sleeved on abandon pipette tips
On guide pillar below cam mechanism, the other end is fixed on top-pressure part.
Described sampling sample-adding all-in-one, the cam abandoned pipette tips cam mechanism and be connected to for eccentric rotary on guide pillar,
The cam top pressure is abandoned at the top of pipette tips connector described, and the cam side turns with abandoning the rotation connection of pipette tips control-rod lower end
The position of dynamic connection meets：Push and abandon pipette tips control-rod, the downward top pressure of cam is abandoned pipette tips connector and moved down.
Second of technical scheme：A kind of microorganism sampling sample-adding all-in-one, including supporting mechanism, some sample loading guns, it is described
Multiple transversal driving mechanisms, vertically movable mechanism are provided with supporting mechanism, sample-adding controlling organization is sampled, abandons pipette tips mechanism；Institute
The support bar that supporting mechanism includes being vertically arranged is stated, rotating disk is rotatably connected on the support bar, the rotating disk is around branch
Strut rotates；The vertically movable mechanism includes vertical guide pillar, vertically movable drive component, the vertically movable drive component
It is arranged on rotating disk or/and guide pillar, the vertically movable drive component drives the guide pillar to move up and down and position；The horizontal stroke
It is connected to drive mechanism with guide pillar and the scattering device centered on guide pillar, transversal driving mechanism connects sample loading gun, drives sample loading gun
Laterally shrink to guide pillar direction or scattered away from guide pillar；The sampling sample-adding controlling organization includes the sample-adding on the sample loading gun of setting
The sample-adding driving group that pressure head, the sample-adding sampling connector, the driving sample-adding control piece that drive sample-adding pressure head to move up and down move up and down
Part, the sample loading gun return unit resetted for sample loading gun；The pipette tips mechanism that abandons includes being sleeved on outside sample loading gun being used for top pressure rifle
What top-pressure part, the driving top-pressure part of head moved up and down abandons pipette tips drive component；The transversal driving mechanism is set including multiple transverse directions
The transversal stretching bar put, transversal stretching bar scattering device centered on guide pillar is multiple and one end of each transversal stretching bar
All it is fixed on guide pillar, the other end of each transversal stretching bar is connected with sample loading gun, and the outermost of the transversal stretching bar is set
It is equipped with the extension and contraction control component for controlling transversal stretching bar transversal stretching；One end of the sample-adding sampling connector, which is sleeved on, to be added
Sample sampling drive component below guide pillar on, the other end be loaded pressure head be fixedly connected；The sample-adding drive component includes fixing
Sample-adding cam mechanism, the sample-adding control-rod being vertically arranged along guide pillar on guide pillar；The sample-adding cam mechanism top pressure is being loaded
Sample at the top of connector, sample-adding cam mechanism rotation driving sample-adding sampling connector moves up and down.
Implement technical scheme, at least with following beneficial effect：A kind of composite structure is used in the present invention,
Multiple sample loading guns are provided with, sample liquid can be added into flat board simultaneously, improve feed rate, and the sample injector of the present invention can be with
The pipette tips of requirement are directly mounted directly from pipette tips box, for sample adding liquid, pipette tips can be destroyed after adding and directly, again
New pipette tips are installed and continue subsequent operation, completely without installing or discarding by hand pipette tips.So both it ensure that during being loaded
Gnotobiosis, feed rate is also improved, ensure that the quick, accurate of sample-adding.
Wherein, supporting mechanism is used to be supported whole sample injector, and rotating disk can rotate along support bar, with profit
In respectively realize dress pipette tips, imbibition, be loaded, abandon pipette tips etc. action.Transversal driving mechanism drives sample loading gun transverse shifting, adapts to not
With position and different operations.Vertically movable mechanism is used to realize the actions such as dress pipette tips, imbibition and sample-adding.Sampling sample-adding control machine
Structure samples to control to be loaded, and abandons pipette tips mechanism and is used to directly abandon pipette tips.
Brief description of the drawings
Below in conjunction with drawings and Examples, the invention will be further described, in accompanying drawing：
Fig. 1 is the structural representation of the embodiment of the present invention；
Fig. 2 is the structural representation of the sample loading gun connection of the embodiment of the present invention；
Fig. 3 is the stereogram of a sample loading gun connection in the embodiment of the present invention；
Fig. 4 is the stereogram in another direction of a sample loading gun connection in the embodiment of the present invention；
Fig. 5 is the sectional view of the embodiment of the present invention；
Fig. 6 is the structural representation of another embodiment in the embodiment of the present invention；
Fig. 7 is partial enlarged drawing at I in Fig. 6；
Fig. 8 is partial enlarged drawing at M in Fig. 2；
Fig. 9 is partial enlarged drawing at N in Fig. 5.
Embodiment
In order to which technical characteristic, purpose and the effect of the present invention is more clearly understood, now compares accompanying drawing and describe in detail
The embodiment of the present invention.
As shown in figs 1-9, a kind of sampling sample-adding all-in-one, including supporting mechanism 100, some sample loading guns 900, the support
Transversal driving mechanism 200, vertically movable mechanism 300 are provided with mechanism 100, sample-adding controlling organization 400 is sampled, abandons pipette tips mechanism
500；The supporting mechanism 100 includes the support bar 101 being vertically arranged, and rotating disk is rotatably connected on the support bar 101
102, the rotating disk 102 rotates around support bar 101；The vertically movable mechanism 300 includes vertical guide pillar 301, vertical
Drive component 302 is moved, the vertically movable drive component 302 is arranged on rotating disk 102 or/and guide pillar 301, described vertical
Motion drive component 302 drives the guide pillar 301 to move up and down and position；The transversal driving mechanism 200 is connected with guide pillar 301
And the scattering device centered on guide pillar 301, transversal driving mechanism 200 connect sample loading gun 900, drive 900 horizontal guide of sample loading gun
Shrink or scattered away from guide pillar 301 in the direction of post 301；The sampling sample-adding controlling organization 400 is included on the sample loading gun 900 of setting
Sample-adding pressure head 401, sample-adding sampling connector 402, the driving sample-adding sampling connector 402 for driving sample-adding pressure head 401 to move up and down
The sample-adding drive component 403 of up and down motion；The pipette tips mechanism 500 that abandons includes being sleeved on outside sample loading gun 900 being used for top pressure rifle
What first 901 top-pressure part 501, driving top-pressure part 501 moved up and down abandons pipette tips drive component 502.
As shown in figures 1 to 6, supporting mechanism 100 is the support of whole device, and support bar 101 is vertically arranged, under support bar 101
Portion is directly anchored on the fixtures such as table top or the bottom of support bar 101 is provided with base, for support bar 101
It is stable.On the one hand the effect of rotating disk 102 is used for the installation of other parts, be on the other hand in use for adjusting sample injector
Need to be directed to and add pipette tips, sampling, be loaded, abandon the action such as pipette tips, carry out position adjustment.Such as：Pipette tips box, sample liquid, flat board, waste
Box is arranged around sample injector surrounding, and sample injector, which just can be realized sequentially, to be added pipette tips, sampling, is loaded, abandons pipette tips, is saved the time, is improved
Efficiency.Rotating disk 102 is rotatably connected on the top of support bar 101.The shapes and sizes of rotating disk 102 are not construed as limiting, Ke Yishe
It is set to the applicable shape such as circular, oval, square.
As shown in Fig. 1,2,5, vertically movable mechanism 300 be for all parts that will be fixed on guide pillar 301 on the whole
Lower movement, in favor of installing pipette tips 901 additional.There are numerous embodiments in vertically movable mechanism 300, and one kind is Fig. 6, shown in 7, described perpendicular
Straight motion drive component 302 connects including the drive rod 326 being vertically arranged, the vertical driving being connected with drive rod 326 and guide pillar 301
Fitting 327, the drive rod 326 drive guide pillar 301 to move up and down up and down through vertical drive connection part 327；It is vertical to drive
Follower link 327 has numerous embodiments, and another kind is：The vertical drive connection part 327 is to be separately positioned on the He of guide pillar 301
Gear 327a and rack 327b on drive rod 326, specifically, rack 327b is arranged on guide pillar 301, gear 327a and driving
Bar 326 connects.
Another kind is Fig. 5, shown in 9, and the rotating disk 102 is provided with mounting hole 121, and the gap of guide pillar 301, which coordinates, is pacifying
Filling in hole 121, the set location of mounting hole 121 deviates the center of rotating disk 102, after being rotated in favor of rotating disk 102, sample loading gun 900
There can be the larger radius of gyration, beneficial to operation.The vertically movable drive component 302 includes the be arranged in rotating disk 102
Positioning piece 321, the second keeper 322 being arranged on guide pillar 301, the in the vertical direction interval of the second keeper 322
Set at least two, guide pillar 301 is determined in first keeper 321 and the clamping of the second keeper 322, grafting or snap together
Position, and the first keeper 321 and the second keeper 322 are mutually disengaged releasing positioning under external force.The upper distal process of guide pillar 301
Go out on rotating disk 102, the convenient guide pillar 301 that operates moves up and down.
The structure of vertically movable drive component 302 can have it is a variety of, as long as can realize positioning and release positioning move up and down
Structure be all suitable for the present invention.For example, the first embodiment is：First keeper 321 is to be arranged on the inwall of mounting hole 121
Neck, the second keeper 322 is to be disposed on elastic chuck on guide pillar 301, and the elastic chuck is connected to the card
Guide pillar 301 is positioned in groove, elastic chuck departs from neck and releases positioning, and same structure can exchange setting, i.e. neck is set
On guide pillar 301, elastic chuck is arranged on the inwall of mounting hole 121.Two are set on elastic chuck vertical direction, original position
It is that the elastic chuck of lower section and neck coordinate positioning, when pushing down on guide pillar 301, the elastic chuck of lower section departs from neck, guide pillar
301 move down, and move to the elastic chuck of top when being caught in neck, sample loading gun 900 be displaced downwardly to plus the pipette tips box of pipette tips 901 in, add
Pipette tips 901；Guide pillar 301 is above carried, is moved up plus the sample loading gun 900 of pipette tips 901, while rotating disk 102 rotates to sample position, can
To be sampled operation.
In order to which guide pillar 301 is easy to operate, operation handle 311 can be installed at the top of guide pillar 301, conveniently push and on
Carry.
Second of embodiment be：First keeper 321 is latch, and the second keeper 322 opens up on guide pillar 301
Positioning hole；The third embodiment：For first keeper 321 to set the snap ring in guide pillar 301 or rotating disk 102, second is fixed
Position part 322 is the corresponding neck in rotating disk 102 or guide pillar 301, and tumble card latch closure is connected in neck, guide pillar 301 is determined
Position, snap ring is routed up, and releases snapping, can be to move up and down guide pillar 301.
As shown in figures 1 to 6, the transversal driving mechanism 200 includes multiple transversal stretching bars 201 laterally set, the horizontal stroke
To expansion link 201, scattering device is multiple centered on guide pillar 301 and one end of each transversal stretching bar 201 is fixed on guide pillar
On 301, the other end of each transversal stretching bar 201 is connected with sample loading gun 900, and the outermost of the transversal stretching bar 201 is set
It is equipped with the extension and contraction control component 202 for controlling the transversal stretching of transversal stretching bar 201；Preferably, in transversal driving mechanism 200
In, principal organ includes：Transversal stretching bar 201, extension and contraction control component 202, the transversal stretching bar 201 include at least two phases
The telescopic unit 211 being mutually set with, wherein transversal stretching bar 201 are arranged around the homogeneous radiation of guide pillar 301, transversal stretching bar 201
Quantity it is consistent with the quantity of sample loading gun 900 of needs.The length root of the quantity of telescopic unit 211 and each telescopic unit 211
According to design whole device size and the position of sample loading gun 900 correlation is shunk, is not limited thereto.
Mutually it is slidably connected between adjacent telescopic unit 211 and prevents the two disengaging by the way that locating part is spacing.It is flexible single
First 211 concrete structures can have diversified forms, if the structure that can serve as the present invention can be slided between each other, such as：Stretch
Contracting unit 211 is sleeve, can be connected together, and telescopic unit 211 can also be litter, and litter stacking, which is slided, to be set, each
Slideway and chute are provided with litter, the slideway of litter is connected with adjacent slide.
The extension and contraction control component 202 includes being rotatably connected on control panel 221 on guide pillar 301, for fixed each plus
The sample loading gun fixture 222 of sample rifle 900, the sliding block 223 being fixedly connected with sample loading gun fixture 222；Opened in the control panel 221
There is multiple arcs control flume 224, each sliding block 223 is inserted into the corresponding arc control flume 224, the sample loading gun
Fixture 222 is fixedly connected with transversal stretching bar 201, rotates control panel 221 and sliding block 223 is slided in arc control flume 224
Sample loading gun 900 is driven to be shunk to guide pillar 301 or away from guide pillar 301.
Control panel 221 is that control panel 221 is rotatablely connected with guide pillar 301, is for controlling the flexible of transversal stretching bar 201
Facilitate operation, control panel 221 is arranged on the top of rotating disk 102 or interlocking in the rotating disk 102, using being arranged on control panel
The embodiment of 221 tops：It is corresponding to be opened up in rotating disk 102 through upper and lower sliding groove 121, pass through rotation for sliding block 223
It is inserted into after rotating disk 102 in the arc control flume 224 of control panel 221, sliding groove 121 sets quantity identical with the quantity of sliding block 223.
Using interlocking in rotating disk 102：Installing port 122 is opened up in the correspondence position of rotating disk 102, control panel 221 is arranged on installation
In mouth 122, gap coordinates between control panel 221 and rotating disk 102, does not influence control panel 221 and rotates freely.Control panel 221
Shape is generally disc, and guide pillar 301 is preferably provided at the center of control panel 221.
Arc control flume 224 is to realize the linear motion of transversal stretching bar 201 by rotating, therefore the arc control flume
224 shape and position meet：900 horizontal straight line of sample loading gun is driven to be contracted to when sliding block 223 slides in arc control flume 224
The direction of guide pillar 301 or remote guide pillar 301.The length of arc control flume 224 meets：Sample loading gun 900 is contracted to center, is beneficial to
Add pipette tips and abandon pipette tips；After transversal stretching bar 201 stretches out, sample loading gun 900 is dispersed to suitable sample-adding and sample position.Arc control
The length of groove 224 processed can be arranged to it is adjustable, for adjusting contraction and the extended position of sample loading gun 900.
Sample loading gun fixture 222 is for being detachably fixed sample loading gun 900, and sample loading gun fixture 222 fixes sample loading gun
900 mode can have a variety of：Sample loading gun fixture 222 clamps sample loading gun 900, sample loading gun 900 is locked in using screw plus
On sample rifle fixture 222, sample loading gun 900 be inserted on sample loading gun fixture 222 etc., be suitable for the present embodiment, therefore, add
The structure of sample rifle fixture 222 is not construed as limiting.Sample loading gun fixture 222 and the outermost telescopic unit 211 of transversal stretching bar 201
It is fixedly connected, the inside and outside movement of the flexible drive sample loading gun 900 of transversal stretching bar 201.
Sliding block 223 is provided with sample loading gun fixture 222, sliding block 223 is upwardly extended in middle arc control flume 224, is used for
Moved by the control slide block 223 of arc control flume 224.The shape of sliding block 223 is not construed as limiting, and only needs sliding block 223 smooth in arc
Slided in shape control flume 224, preferably sliding block 223 is cylinder.
As shown in figures 1-8, in described sampling sample-adding all-in-one, another important component is sampling sample-adding controlling organization
400, the sampling of the mechanism controls sample loading gun 900 and sample-adding.Sampling sample-adding controlling organization 400 includes sample-adding pressure head 401, sample-adding takes
Sample connector 402, sample-adding drive component 403.
The sample loading gun 900 include be used for contain sample sample-adding cylinder 902, for pipette samples or push sample plus
Sample push rod 903；Sample-adding push rod 903 is inserted into sample-adding cylinder 902, promotes sample-adding push rod 903 to move up to original position.
The bottom of sample-adding push rod 903 in sample-adding cylinder 902 is provided with piston 904, and sample-adding return unit 905 is arranged on sample-adding push rod 903 top
Outside, sample-adding return unit 905 can be diversified forms, such as the spring of pretension, be loaded the top pressure of pressure head 401, be loaded under push rod 903
Move, sample-adding pressure head 401 does not apply pressure, then is being loaded in the presence of return unit 905 on sample-adding push rod 903 and sample-adding pressure head 401
Move and reset, sample liquid is sucked in sample-adding cylinder 902 or resets to wait and inhales sample liquid next time.The control of sampling amount is loaded by adjusting
Return unit 905 realizes, such as：The extension length of preloading spring is adjusted, upholds length difference, sampling amount is just different, passes through adjustment
Spring can adjusts sampling amount.
Sample-adding sampling connector 402 is generally laterally set, and sample-adding sampling connector 402 is mutually covered by multiple connecting piece units
Composition is connect, sample-adding sampling connector 402 carries out transversal stretching with transversal stretching bar 201.The one of the sample-adding sampling connector 402
End is sleeved on the guide pillar 301 of the lower section of sample-adding drive component 403, the other end is fixedly connected with sample-adding pressure head 401, and sample-adding sampling connects
Fitting 402 acts with sample-adding pressure head 401.
The sample-adding drive component 403 includes being fixed on sample-adding cam mechanism 431 on guide pillar 301, vertical along guide pillar 301
The sample-adding control-rod 432 of setting；The sample-adding top pressure of cam mechanism 431 is in the top of sample-adding sampling connector 402, sample-adding cam machine
The rotation driving of structure 431 sample-adding sampling connector 402 moves up and down.Sample-adding cam mechanism 431 has multiple structural forms, as long as energy
The structure for driving sample-adding sampling connector 402 to move up and down is suitable for the present invention.In the present embodiment, as shown in figure 8, described add
Sample cam mechanism 431 includes being sleeved on guide pillar 301 and upper and lower intermeshing first cam 431a and the second cam 431b, institute
It is respectively tubular to state the first cam 431a and the second cam 431b, and the two end face being in contact all is tooth form or waveform；It is described
First cam 431a is connected with sample-adding control-rod 432 and rotated by being loaded the control of control-rod 432, the second cam 431b tops
It is pressed in the top of sample-adding sampling connector 402.Sample-adding control-rod 432 top passes rotating disk 102, can directly control sample-adding control
Bar 432 is loaded, sampled.Sample-adding control-rod 432 lower end is provided with gear 434, the axially arranged tooth with the first cam 431a
The engagement of wheel 435, the rotation that will be loaded the up and down motion of control-rod 432 or convert rotational motion is the first cam 431a, drives
Second cam 431b moves up and down, and so as to realize the up and down motion of sample-adding sampling connector 402, the second cam 431b takes with sample-adding
Sample connector 402 can be fixedly connected or end contact.
As shown in figures 1 to 6, in described sampling sample-adding all-in-one, the pipette tips drive component 502 of abandoning includes being fixed on leading
Abandoning pipette tips cam mechanism 521, abandoning pipette tips connector 522, along guide pillar 301 with abandon the cooperation of pipette tips cam mechanism 521 on post 301
It is vertically arranged and abandons pipette tips control-rod 523, the top resetted upwards for top-pressure part 501 with abandon that pipette tips cam mechanism 521 is connected
Return unit 524 is pressed, pipette tips connector 522 is abandoned and generally laterally sets, abandon pipette tips connector 522 and mutually covered by multiple connecting piece units
Composition is connect, pipette tips connector 522 is abandoned and carries out transversal stretching with transversal stretching bar 201.It is described to abandon the one end of pipette tips connector 522 suit
On the guide pillar 301 below pipette tips cam mechanism 521 is abandoned, the other end is fixed on top-pressure part 501.Top-pressure part 501 is to be sleeved on
Tubular structure outside sample loading gun 900, the end face of the end face face pipette tips 901 of its lower end, abandon the drive of pipette tips cam mechanism 521 and abandon rifle
Head connector 522 moves downward, then top-pressure part 501 moves downward, and top pressure falls pipette tips 901.Top pressure return unit 524 is arranged on top pressure
Outside part 501, for the top-pressure part moved downward 501 to be reset into original position upwards.The selection of top pressure return unit 524 is spiral bullet
Spring, top-pressure part 501 move down spring compression, release the effect of top pressure rear coil springs elastic force, and top-pressure part 501 moves up reset.Remove
Outside selection helical spring, it is also an option that other elastic constructions, such as torsion spring etc..
Abandoning pipette tips cam mechanism 521 has various structures, and the pipette tips cam mechanism 521 of abandoning is connected to guide pillar for eccentric rotary
Cam on 301, the cam top pressure abandon the top of pipette tips connector 522 described, and the cam side is with abandoning pipette tips control-rod
523 lower ends are rotatablely connected, and the position of rotation connection meets：Push and abandon pipette tips control-rod 523, the downward top pressure of cam abandons pipette tips connection
Part 522 moves down.Cam can be the irregular shape of disc, oval dish type or other different radiis.Abandon pipette tips control
Bar 523 processed is vertically arranged, and its upper end passes rotating disk 102, for manually control, push abandon pipette tips control-rod 523 can with will
Pipette tips 901 are removed.
As shown in figures 1 to 6, specific implementation process：Pipette tips box, the reagent bottle for containing sample liquid, flat board, waste holder are surrounded and added
The surrounding of support bar 101 of sample device is set, and the transversal driving mechanism 200 of sample injector is in contraction state, and sample loading gun 900 is also contracted in
Together, adapt to the close arrangement of pipette tips in pipette tips box, in the mutual spacing of sample loading gun 900 and pipette tips box between pipette tips between
Away from consistent, the arrangement of the two is also consistent.The pipette tips 901 that rotating disk 102 causes sample loading gun 900 to be aligned in pipette tips box are rotated first,
Guide pillar 301 is pushed, all mechanisms being connected with guide pillar 301 are moved down, and sample loading gun 900 is displaced downwardly in pipette tips box, directly by pipette tips 901
It is fitted on sample loading gun 900, then above carries guide pillar 301, sample loading gun 900 moves up, and then rotates rotating disk 102 so that sample loading gun
900 alignment sample liquids, push guide pillar 301 so that and the pipette tips of sample loading gun 900 are inserted into sample liquid, after sample-adding control-rod 432 pushes,
Pipette tips 901 just draw sample liquid, then above carry guide pillar 301, and sample loading gun 900 leaves sample liquid；Rotate on rotating disk 102 to flat board
Side, rotate control panel 221 and the transverse shifting of sample loading gun 900 is deployed to surrounding, be directed at flat board, push guide pillar 301, sample loading gun
900 move at flat board, push sample-adding control-rod 432, and sample-adding push rod 903, which moves down, extrudes sample liquid；After the completion of sample-adding, rotation is rotated
Disk 102 rotates backward control panel 221 to waste holder, then at the cross-direction shrinkage of sample loading gun 900 to guide pillar 301, is directed at waste holder, under
Pressure abandons pipette tips control-rod 523, then is dropped down onto under pipette tips 901 in waste holder, and completion is once loaded process.In whole process, entirely without
Need hand contact pipette tips 901 and sample liquid, ensure that the gnotobiosis during sample-adding, meanwhile, all steps to be by rotation, under
The simple operations such as pressure are realized, are moved while accelerating feed rate, simplify load procedure, and can realize multiple sample loading gun 900
Make, be integrally improved feed rate.Furthermore it is possible to set the original position of sample-adding push rod 903 in advance, sample-adding can be accurately controlled
Amount, and the consistent of multiple sample-adding amounts of sample loading gun 900 is kept, improve experimental precision.
The preferred embodiments of the present invention are the foregoing is only, are not intended to limit the invention, for the skill of this area
For art personnel, the present invention can have various changes, combination and change.Within the spirit and principles of the invention, made
Any modification, equivalent substitution and improvements etc., should be included within scope of the presently claimed invention.
Claims (10)
1. one kind sampling sample-adding all-in-one, it is characterised in that including supporting mechanism, some sample loading guns, set on the supporting mechanism
It is equipped with and abandons pipette tips mechanism, vertically movable mechanism, sampling sample-adding controlling organization, transversal driving mechanism；
The supporting mechanism includes the support bar being vertically arranged, and rotating disk, the rotating disk are rotatably connected on the support bar
Rotated around support bar；
The vertically movable mechanism includes vertical guide pillar, vertically movable drive component, and the vertically movable drive component is set
In rotating disk or/and guide pillar, the vertically movable drive component drives the guide pillar to move up and down and position；
The transversal driving mechanism is connected with guide pillar and the scattering device centered on guide pillar, transversal driving mechanism connection sample loading gun,
Sample loading gun is driven laterally to shrink to guide pillar direction or scattered away from guide pillar；
It is described sampling sample-adding controlling organization include set sample loading gun on sample-adding pressure head, drive sample-adding pressure head move up and down add
The sample-adding drive component that sample sampling connector, driving sample-adding control piece move up and down；
The pipette tips mechanism that abandons moves up and down including top-pressure part, the driving top-pressure part for top pressure pipette tips being sleeved on outside sample loading gun
Abandon pipette tips drive component.
2. sampling sample-adding all-in-one according to claim 1, it is characterised in that the vertically movable drive component includes perpendicular
The drive rod directly set, the vertical drive connection part being connected with drive rod and guide pillar, the drive rod is up and down through vertical
Drive connection part drives guide pillar to move up and down；
Or the rotating disk is provided with mounting hole, the guide pillar gap coordinates in mounting hole and moved up and down, the vertical fortune
The second keeper that dynamic drive component includes setting the first keeper on the rotating pan, is arranged on guide pillar, described second is fixed
Position part in the vertical direction is arranged at intervals at least two, first keeper and the second keeper clamping, grafting or snaps onto
Guide pillar is positioned together, and the first keeper and the second keeper are mutually disengaged releasing positioning under external force.
3. sampling sample-adding all-in-one according to claim 1, it is characterised in that the transversal driving mechanism includes multiple horizontal strokes
To the transversal stretching bar of setting, transversal stretching bar scattering device centered on guide pillar is multiple and each transversal stretching bar
One end is all fixed on guide pillar, and the other end of each transversal stretching bar is connected with sample loading gun, the outermost of the transversal stretching bar
Side is provided with the extension and contraction control component for controlling transversal stretching bar transversal stretching.
4. sampling sample-adding all-in-one according to claim 3, it is characterised in that the extension and contraction control component includes the company of rotation
The control panel that is connected on guide pillar, the sample loading gun fixture for fixing each sample loading gun, it is fixedly connected with sample loading gun fixture
Sliding block；Multiple arcs control flume is provided with the control panel, each sliding block is inserted into the corresponding arc control flume,
The sample loading gun fixture is fixedly connected with transversal stretching bar, is rotated control panel and is caused sliding block slides to drive in arc control flume to add
Sample rifle shrinks to guide pillar or away from guide pillar；The shape of the arc control flume and position meet：Sliding block is sliding in arc control flume
Sample loading gun transverse direction straight line is driven to be contracted to guide pillar direction or away from guide pillar when dynamic.
5. sampling sample-adding all-in-one according to claim 1, it is characterised in that one end set of the sample-adding sampling connector
Mounted in sample-adding drive component below guide pillar on, the other end be loaded pressure head be fixedly connected；The sample-adding drive component includes solid
Sample-adding cam mechanism, the sample-adding control-rod being vertically arranged along guide pillar being scheduled on guide pillar；The sample-adding cam mechanism top pressure is adding
At the top of sample sampling connector, sample-adding cam mechanism rotation driving sample-adding sampling connector moves up and down.
6. sampling sample-adding all-in-one according to claim 5, it is characterised in that the sample-adding cam mechanism includes being sleeved on
Intermeshing first cam and the second cam, first cam and the second cam are respectively tubular on guide pillar and up and down, and two
The end face that person is in contact all is tooth form or waveform；First cam is connected and by being loaded control-rod control with sample-adding control-rod
System rotation, the second cam top pressure is at the top of sample-adding sampling connector.
7. sampling sample-adding all-in-one according to claim 1, it is characterised in that the sample loading gun includes being used to contain sample
Sample-adding cylinder, for pipette samples or push sample sample-adding push rod, sample-adding push rod be inserted into sample-adding cylinder in.
8. sampling sample-adding all-in-one according to claim 1, it is characterised in that the pipette tips drive component of abandoning includes fixing
Pipette tips cam mechanism is abandoned on guide pillar, with abandoning abandoning pipette tips connector, being vertically arranged simultaneously along guide pillar for pipette tips cam mechanism cooperation
Pipette tips control-rod, the top pressure return unit resetted upwards for top-pressure part are abandoned with abandon that pipette tips cam mechanism is connected, it is described to abandon pipette tips
Connector one end is sleeved on the guide pillar abandoned below pipette tips cam mechanism, the other end is fixed on top-pressure part.
9. sampling sample-adding all-in-one according to claim 8, it is characterised in that the pipette tips cam mechanism of abandoning turns to be eccentric
The dynamic cam being connected on guide pillar, the cam top pressure are abandoned at the top of pipette tips connector described, and the cam side is with abandoning pipette tips
Control-rod lower end is rotatablely connected, and the position of rotation connection meets：Push and abandon pipette tips control-rod, the downward top pressure of cam abandons pipette tips connection
Part moves down.
10. one kind sampling sample-adding all-in-one, it is characterised in that including supporting mechanism, some sample loading guns, set on the supporting mechanism
Transversal driving mechanism, vertically movable mechanism are equipped with, sample-adding controlling organization is sampled, abandons pipette tips mechanism；
The supporting mechanism includes the support bar being vertically arranged, and rotating disk, the rotating disk are rotatably connected on the support bar
Rotated around support bar；
The vertically movable mechanism includes vertical guide pillar, vertically movable drive component, and the vertically movable drive component is set
In rotating disk or/and guide pillar, the vertically movable drive component drives the guide pillar to move up and down and position；
The transversal driving mechanism is connected with guide pillar and the scattering device centered on guide pillar, transversal driving mechanism connection sample loading gun,
Sample loading gun is driven laterally to shrink to guide pillar direction or scattered away from guide pillar；
It is described sampling sample-adding controlling organization include set sample loading gun on sample-adding pressure head, drive sample-adding pressure head move up and down add
The sample-adding drive component that sample sampling connector, driving sample-adding control piece move up and down；
The pipette tips mechanism that abandons moves up and down including top-pressure part, the driving top-pressure part for top pressure pipette tips being sleeved on outside sample loading gun
Abandon pipette tips drive component；
The transversal driving mechanism includes multiple transversal stretching bars laterally set, and the transversal stretching bar is divided centered on guide pillar
It is casually arranged with and puts one end of multiple and each transversal stretching bar and be fixed on guide pillar, the other end of each transversal stretching bar connects
There is sample loading gun, the outermost of the transversal stretching bar is provided with the extension and contraction control group for controlling transversal stretching bar transversal stretching
Part；
One end of the sample-adding sampling connector is sleeved on the guide pillar below sample-adding drive component, the other end is consolidated with sample-adding pressure head
Fixed connection；The sample-adding drive component includes the sample-adding cam mechanism being fixed on guide pillar, the sample-adding control being vertically arranged along guide pillar
Bar processed；At the top of sample-adding sampling connector, the rotation driving sample-adding sampling of sample-adding cam mechanism connects the sample-adding cam mechanism top pressure
Fitting moves up and down.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510466722.0A CN105004576B (en) | 2015-07-31 | 2015-07-31 | Sampling sample-adding all-in-one |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510466722.0A CN105004576B (en) | 2015-07-31 | 2015-07-31 | Sampling sample-adding all-in-one |
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| Publication Number | Publication Date |
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| CN105004576A CN105004576A (en) | 2015-10-28 |
| CN105004576B true CN105004576B (en) | 2017-11-10 |
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| CN201510466722.0A Active CN105004576B (en) | 2015-07-31 | 2015-07-31 | Sampling sample-adding all-in-one |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106124241B (en) * | 2016-08-10 | 2018-08-07 | 山东新马制药装备有限公司 | The sampling device of solid hard capsule |
| CN108490202A (en) * | 2018-04-09 | 2018-09-04 | 杭州杭睿科技有限公司 | A kind of automatic detection device of medicine sample |
| CN108693369A (en) * | 2018-04-09 | 2018-10-23 | 杭州杭睿科技有限公司 | A kind of sampler detected automatically for sample |
| CN113203602B (en) * | 2021-05-24 | 2022-10-04 | 重庆医科大学附属第一医院 | Sampling device for medical examination |
| CN114100719A (en) * | 2021-11-29 | 2022-03-01 | 曹振 | Medical treatment sample processing apparatus |
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| WO2002039084A2 (en) * | 2000-10-25 | 2002-05-16 | Dna Sciences, Inc. | Variable geometry fluid sample loader |
| CN201754157U (en) * | 2010-08-05 | 2011-03-02 | 彭为生 | Automatic sample injector |
| WO2011157794A1 (en) * | 2010-06-18 | 2011-12-22 | Tecan Trading Ag | Spread sheare |
| CN102539806A (en) * | 2012-02-16 | 2012-07-04 | 哈尔滨工业大学（威海） | Multi-channel liquid sampling equivalent distancing device |
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|---|---|---|---|---|
| US4311667A (en) * | 1979-04-19 | 1982-01-19 | Olympus Optical Company Limited | Delivering apparatus |
| WO2002039084A2 (en) * | 2000-10-25 | 2002-05-16 | Dna Sciences, Inc. | Variable geometry fluid sample loader |
| WO2011157794A1 (en) * | 2010-06-18 | 2011-12-22 | Tecan Trading Ag | Spread sheare |
| CN201754157U (en) * | 2010-08-05 | 2011-03-02 | 彭为生 | Automatic sample injector |
| CN102539806A (en) * | 2012-02-16 | 2012-07-04 | 哈尔滨工业大学（威海） | Multi-channel liquid sampling equivalent distancing device |
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| Publication number | Publication date |
|---|---|
| CN105004576A (en) | 2015-10-28 |
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Address after: 502, block B, Heping building, 2049 Heping Road, Luohu District, Shenzhen, Guangdong 518000 Patentee after: SHENZHEN ACADEMY OF INSPECTION AND QUARANTINE Patentee after: Shenzhen Customs Food Inspection and Quarantine Technology Center Address before: 502, block B, Heping building, 2049 Heping Road, Luohu District, Shenzhen, Guangdong 518000 Patentee before: SHENZHEN ACADEMY OF INSPECTION AND QUARANTINE Patentee before: FOOD INSPECTION CENTER OF CIQ-SHENZHEN |