CN106955752A - A kind of perforated plate sampling height adjustor - Google Patents
A kind of perforated plate sampling height adjustor Download PDFInfo
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- CN106955752A CN106955752A CN201710284533.0A CN201710284533A CN106955752A CN 106955752 A CN106955752 A CN 106955752A CN 201710284533 A CN201710284533 A CN 201710284533A CN 106955752 A CN106955752 A CN 106955752A
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- gear
- pedestal
- lifting
- hoistable platform
- plate
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- 238000005070 sampling Methods 0.000 title claims abstract description 48
- 230000007246 mechanism Effects 0.000 claims abstract description 63
- NJPPVKZQTLUDBO-UHFFFAOYSA-N novaluron Chemical compound C1=C(Cl)C(OC(F)(F)C(OC(F)(F)F)F)=CC=C1NC(=O)NC(=O)C1=C(F)C=CC=C1F NJPPVKZQTLUDBO-UHFFFAOYSA-N 0.000 claims abstract description 45
- 230000003028 elevating effect Effects 0.000 claims abstract description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 230000003068 static effect Effects 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 description 22
- 238000000034 method Methods 0.000 description 8
- 238000010586 diagram Methods 0.000 description 4
- MLFHJEHSLIIPHL-UHFFFAOYSA-N isoamyl acetate Chemical class CC(C)CCOC(C)=O MLFHJEHSLIIPHL-UHFFFAOYSA-N 0.000 description 3
- 238000012546 transfer Methods 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 229920005439 Perspex® Polymers 0.000 description 2
- 238000005213 imbibition Methods 0.000 description 2
- 238000000622 liquid--liquid extraction Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 238000000638 solvent extraction Methods 0.000 description 2
- 238000002965 ELISA Methods 0.000 description 1
- 241000237858 Gastropoda Species 0.000 description 1
- 241001310793 Podium Species 0.000 description 1
- 230000001464 adherent effect Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229940117955 isoamyl acetate Drugs 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
- B01L3/0213—Accessories for glass pipettes; Gun-type pipettes, e.g. safety devices, pumps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
Landscapes
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a kind of perforated plate sampling height adjustor, including:The elevating mechanism that porous plate, hoistable platform, pedestal and orifice plate to be measured and control hoistable platform are moved up and down, porous plate level is plugged on hoistable platform, the hole position of porous plate is used for fixed liquid-transfering gun pipette tips vertically, orifice plate to be measured is arranged on pedestal, porous plate is located at the surface of orifice plate to be measured, and the hole position one-to-one corresponding on porous plate and orifice plate to be measured.During hoistable platform is moved, due to being Open architecture between hoistable platform and pedestal, field range is more broad, pipette tips attitude can be observed in real time, and whether whether correct and pipette tips end is located at correct hole slot position, so as to ensure that liquid-transfering gun pipette tips are in vertical position all the time, pipette tips can be avoided to insert adjacent hole slot.Due in use, the height and attitude of single adjustment pipette tips, and orifice plate to be measured is in fixed static position all the time, its is simple to operate, and the situation for inhaling adjacent hole by mistake can be avoided to occur.
Description
Technical field
The present invention relates to field of experiment equipment, more particularly to a kind of perforated plate sampling height adjustor.
Background technology
In experimental facilities and clothing arts, the reaction vessel of milligram ammonia is relative to traditional shaking flask, test tube, treatment liquid
Amount only has hundreds of or even several tens of microliters, therefore is widely used in fields such as life science, medicine, chemistry.It is operated
Generally completed using the pipettor of single channel or multichannel.But when carrying out solid-liquor separation or liquid-liquid extraction, using manual
Operation is difficult to precise control liquid-transfering gun pipette tips and is properly inserted the liquid layer to be drawn specified, such as is drawn in liquid-liquid extraction and treat imbibition
Upper phase or lower phase when, due to it is manually operated when deviation, often cause liquid-transfering gun pipette tips stretch into its adjacent liquid layer, cause miss
Inhale.Existing orifice plate sampling height adjustor is generally using fixed liquid-transfering sucker highly, high by adjusting microwell plate or deep-well plates
The mode of degree so that suction nozzle reaches the specified altitude assignment of orifice plate liquid filling hole.In this mode, operator needs to pay close attention to pipettor simultaneously
Or the attitude of liquid-transfering gun and control adjust deep-well plates or porous plate highly, use operation more inconvenient.Also, for 48 holes,
Spacing between the high density holes microwell plate such as 96 holes and 384 holes and deep-well plates, liquid filling hole is minimum, and slight inclination occurs for liquid-transfering gun attitude
When, it can also shine into pipette tips and deviate corresponding aperture, and adjacent hole slot is inhaled by mistake.Also, existing perforated plate sampling height adjustor is using envelope
Closed type structure, it is impossible to observe liquid level position in the position and hole of liquid-transfering gun attitude and suction nozzle end.In manually operated, liquid relief
Rifle can not avoid the occurrence of trickle deviation, and observation pipette tips attitude is difficult in addition and carries out amendment adjustment in real time, very easy to miss
Inhale adjacent hole.In addition, Multi-channel liquid transfer device (the also referred to as volley of rifle fire) is in operating specification, except requiring that suction nozzle can be properly inserted correspondence
Outside microwell plate or porous plate hole slot, accurate liquid operation also needs to be controlled suction nozzle attitude so that suction nozzle end presses close to micro-
Adherent sample-adding (reference is carried out at orifice plate or deep-well plates liquid level《The ELISA Guide Book》John R.Crowther writings,
Humana Press are published, chapter 3, page 57, Fig.3).This requires that in operation, user must see at the moment
Suction nozzle attitude and position are examined, this is difficult in the orifice plate sampling height adjustor of existing enclosed construction.
Therefore, how porous plate sampling height adjuster that is a kind of easy to operate and can avoiding suction by mistake is provided, is ability
Field technique personnel are badly in need of the technical problem solved.
The content of the invention
It is an object of the invention to provide a kind of perforated plate sampling height adjustor, operation can be effectively solved inconvenient, easy
The problems such as inhaling by mistake.
In order to solve the above technical problems, the invention provides following technical scheme:
A kind of perforated plate sampling height adjustor, including:Porous plate, hoistable platform, pedestal and orifice plate to be measured and control
The elevating mechanism that the hoistable platform is moved up and down is made, the porous plate level is plugged on the hoistable platform, described many
The hole position of hole plate is used for fixed liquid-transfering gun pipette tips vertically, and the orifice plate to be measured is arranged on the pedestal, the porous plate
Hole position on the surface of the orifice plate to be measured, and the porous plate and the orifice plate to be measured is corresponded.
Preferably, the elevating mechanism is scissor-type lifting mechanism, guide tracked rack-gear type elevating mechanism, worm and gear
One kind in formula elevating mechanism.
Preferably, the scissor-type lifting mechanism includes scissor arms turning end and scissor arms sliding end, and the scissor arms turn
Moved end be separately fixed on the pedestal and the hoistable platform on, the scissor arms sliding end respectively with the pedestal and institute
State hoistable platform to be slidably connected, the scissor-type lifting mechanism also includes drive mechanism, the drive mechanism, which is used to drive, to be slided
The scissor arms sliding end level being connected on the pedestal is slided.
Preferably, the scissor-type lifting mechanism is located at the described of both sides relative on the pedestal including two groups and cut respectively
Yoke turning end and the scissor arms sliding end.
Preferably, the drive mechanism include cross bar, screw rod, first gear and and the first gear it is intermeshing
Second gear, the number of teeth of the first gear is more than the number of teeth of the second gear, and the second gear is coaxially fixed on described
On screw rod, the second gear is also coaxially connected with vernier knob, and the first gear is coaxially connected with coarse adjustment knob, described thick
Knob and the vernier knob is adjusted to be respectively positioned on the lateral surface of the pedestal, the two ends of the cross bar are respectively and on the pedestal
The scissor arms sliding end connection of both sides, the cross bar, which is provided with spiral shell block, the spiral shell block, is provided with screw thread, and the screw rod passes through
The screw thread, which runs through in the spiral shell block, the pedestal, is additionally provided with the first retaining mechanism for preventing the screw rod from freely rotating.
Preferably, the guide tracked rack-gear type elevating mechanism includes lifting slider and lifting support, the lifting branch
Post is vertically arranged on the pedestal, and the lifting support is provided with trapezoidal rails, and the trapezoidal rails are provided with tooth bar, described
It is provided with the dovetail groove that lifting slider is provided with and the trapezoidal rails cooperate, the lifting slider and the tooth bar is mutual
The 3rd gear coordinated, the 3rd gear is coaxially connected with the first lifting knob, the lifting slider by first rotating shaft
It is additionally provided with the second retaining mechanism for preventing that the 3rd gear from freely rotating.
Preferably, second retaining mechanism includes the dovetail groove holding out against the jackscrew in the trapezoidal rails, or
Including ratchet and pawl, the jackscrew is horizontally set on the side wall of the lifting slider, the ratchet and the 3rd gear
Coaxially connected, the ratchet is arranged in the lifting slider, and pawl axis is provided with the lifting slider, and the pawl axis is coaxial
Height hook knob is connected with, the ratchet can be embedded in by the rotation of the height hook knob or depart from the ratchet.
Preferably, the Worm-gear type elevating mechanism includes vertical on intermeshing worm gear and worm screw, the pedestal
It is provided with lifting support, the lifting support and is provided with cylinder slotted eye, the worm screw is vertically arranged in the lifting support
In cylinder slotted eye, the upper end of the worm screw and hoistable platform connection, the lifting support is interior to be provided with worm gear, the worm gear
Both sides are connected with second lifting knob by the second rotating shaft respectively.
Preferably, the hoistable platform and/or the porous plate are transparent hoistable platform and/or transparent porous plate.
Preferably, the pedestal is provided with limiting section, and the limiting section is used to ensure the orifice plate to be measured and described porous
Hole position on plate is corresponded.
Compared with prior art, above-mentioned technical proposal has advantages below:
A kind of perforated plate sampling height adjustor provided by the present invention, including:Porous plate, hoistable platform, pedestal and
The elevating mechanism that orifice plate to be measured and control hoistable platform are moved up and down, porous plate level is plugged on hoistable platform, porous
Hole position on plate is used for fixed liquid-transfering gun pipette tips vertically, and orifice plate to be measured is arranged on pedestal, and porous plate is located at orifice plate to be measured
Surface, and hole position on porous plate and orifice plate to be measured corresponds.During hoistable platform is moved, it is only necessary to single
It is that can be achieved to carry out deep-well plates or porous plate fixed height sampling that liquid-transfering gun attitude, which is adjusted, with height.And due to hoistable platform and base
It is Open architecture between seat, field range is more broad, pipette tips appearance can be observed in real time clearly during descending operation
Whether whether correct and pipette tips end is located at correct hole slot position to state, so as to ensure that liquid-transfering gun pipette tips are in vertical position all the time
Put, pipette tips can be avoided to insert adjacent hole slot.During the device use of the present patent application, it is single adjustment pipette tips height with
Attitude, and orifice plate to be measured is in fixed static position all the time, its is simple to operate, and the situation for inhaling adjacent hole by mistake can be avoided to occur.
Brief description of the drawings
, below will be to embodiment or prior art in order to illustrate more clearly of technical scheme of the invention or of the prior art
The accompanying drawing to be used needed for description is briefly described, it should be apparent that, drawings in the following description are some of the present invention
Embodiment, for those of ordinary skill in the art, on the premise of not paying creative work, can also be attached according to these
Figure obtains other accompanying drawings.
A kind of structural representation for perforated plate sampling height adjustor that Fig. 1 is provided for the first specific embodiment of the invention
Figure;
A kind of structural representation for perforated plate sampling height adjustor that Fig. 2 is provided by second of specific embodiment of the invention
Figure;
A kind of base interior for perforated plate sampling height adjustor that Fig. 3 is provided by second of specific embodiment of the invention
Structural representation;
A kind of drive mechanism for perforated plate sampling height adjustor that Fig. 4 is provided by second of specific embodiment of the invention
Structural representation;
A kind of structural representation for perforated plate sampling height adjustor that Fig. 5 is provided for the third specific embodiment of the invention
Figure;
A kind of guide tracked tooth for perforated plate sampling height adjustor that Fig. 6 is provided for the third specific embodiment of the invention
The structural representation of bar gear type elevating mechanism;
A kind of guide tracked tooth for perforated plate sampling height adjustor that Fig. 7 is provided for the third specific embodiment of the invention
The internal structure schematic diagram of bar gear type elevating mechanism;
A kind of guide tracked tooth for perforated plate sampling height adjustor that Fig. 8 is provided for the third specific embodiment of the invention
The vertical view cross section structure diagram of bar gear type elevating mechanism;
A kind of perforated plate sampling height adjustor that Fig. 9 is provided for the third of the invention specific embodiment has a jackscrew
The overlooking the structure diagram of second retaining mechanism;
A kind of structure for perforated plate sampling height adjustor that Figure 10 is provided for the 4th kind of specific embodiment of the invention is shown
It is intended to;
A kind of worm gear snail for perforated plate sampling height adjustor that Figure 11 is provided for the 4th kind of specific embodiment of the invention
The structural representation of rod type up-down mechanism;
A kind of structure of the porous plate for perforated plate sampling height adjustor that Figure 12 is provided by the embodiment of the present invention is shown
It is intended to;
A kind of section view knot of the porous plate for perforated plate sampling height adjustor that Figure 13 is provided by the embodiment of the present invention
Structure schematic diagram.
Reference is as follows:
1 is porous plate, and 11 be the hole position of porous plate, and 12 be handle, and 2 be hoistable platform, and 21 be slot, and 3 be pedestal,
31 be sliding groove, and 32 be limiting section, and 4 be orifice plate to be measured, the hole slot of 41 orifice plates to be measured, and 411 be phase in two-phase prepare liquid, and 412 are
Phase under two-phase prepare liquid, 5 be elevating mechanism, and 51 be scissor arms, and 511 be scissor arms turning end, and 512 be scissor arms sliding end, and 6 are
Liquid-transfering gun, 71 be coarse adjustment knob, and 72 be vernier knob, and 73 be lock-button, and 74 be cross bar, and 75 be spiral shell block, and 76 be screw rod, and 77 be the
One gear, 78 be second gear, and 79 be slide bolt, and 771 be the first ratchet, and 731 be the first ratchet, and 520 be jackscrew, and 521 are
Lifting support, 522 be lifting slider, and 523 be the first lifting knob, and 524 be height hook knob, and 525 be trapezoidal rails, 526
It is the 3rd gear for tooth bar, 527,528 be the second ratchet, and 529 be the second ratchet, and 5231 be first rotating shaft, and 5241 be pawl axis,
5211 be dovetail groove sidewall, and 531 be worm screw, and 532 be the second lifting knob, and 533 be worm gear, and 534 be lifting support, and 535 be circle
Post slotted eye, 536 be the second rotating shaft.
Embodiment
Just as described in the background section, current perforated plate sampling height adjustor easily blocks regarding for liquid-transfering gun pipette tips
Wild scope, and it is difficult to ensure that liquid-transfering gun pipette tips are inserted vertically into the hole slot of orifice plate to be measured, one-handed performance is difficult in addition and right
The precise control of liquid transfer gun head attitude during liquid relief liquid feeding.
On the basis of the studies above, the embodiments of the invention provide a kind of perforated plate sampling height adjustor, rising
During drop, liquid-transfering gun pipette tips are in vertical position all the time, and pipette tips can be avoided to insert in adjacent hole slot, and hoistable platform
Field range between pedestal is more broad, can clearly observe whether pipette tips are inserted perpendicularly into correct hole slot, in addition only
Operation can be sampled by needing single adjustment pipette tips height and attitude, therefore relative to traditional liquid relief mode, not only liquid relief side
Just, and can avoid by mistake inhale situation occur.
In order that the above objects, features and advantages of the present invention can become apparent it is understandable, below in conjunction with the accompanying drawings to this hair
Bright embodiment is described in detail.
Detail is elaborated in the following description to fully understand the present invention.But the present invention can with it is a variety of not
It is same as other manner described here to implement, those skilled in the art can do class in the case of without prejudice to intension of the present invention
Like popularization.Therefore the present invention is not limited by following public embodiment.
It refer to Fig. 1-Figure 13.
A kind of perforated plate sampling height adjustor that first embodiment of the invention is provided, including:Porous plate 1, liter
The elevating mechanism 5 that drop platform 2, pedestal 3 and orifice plate to be measured 4 and control hoistable platform 2 are moved up and down, the porous level of plate 1 is inserted
It is connected on hoistable platform 2, the hole position 11 of porous plate is used for the fixed pipette tips of liquid-transfering gun 6 vertically, and orifice plate 4 to be measured is arranged on pedestal 3
On, porous plate 1 is located at the surface of orifice plate 4 to be measured, and the hole position one-to-one corresponding on porous plate 1 and orifice plate to be measured 4.
During the perforated plate sampling height adjustor provided using the present embodiment, selection first is mutually matched with orifice plate 4 to be measured
Porous plate 1 (be wherein mutually matched refer to hole on porous plate 1 and orifice plate 4 to be measured arrangement mode and Kong Yukong it
Between centre-to-centre spacing should be consistent with each other), then porous plate 1 is inserted in the slot 21 on hoistable platform 2, it is ensured that porous plate 1
Corresponded with above and below the hole position on orifice plate 4 to be measured, in the hole position 11 that the pipette tips of liquid-transfering gun 6 are inserted to porous plate, you can regulation
Elevating mechanism 5, adjusts the specified location of suction range liquid level into the hole slot 41 of orifice plate to be measured of the pipette tips of liquid-transfering gun 6, such as two-phase
Phase 412 under phase 411 or two-phase prepare liquid, then fixes the height of elevating mechanism 5 in prepare liquid, and the liquid relief for determine height is grasped
Make.It is important that, it is only necessary to it is orifice plate 4 to be measured that the single adjustment attitude of liquid-transfering gun 6 can be achieved to deep-well plates or porous plate with height
Fixed height is carried out to sample.And due to being Open architecture between hoistable platform 2 and pedestal 3, field range is more broad, can be clear
During descending operation, pipette tips attitudes is observed in real time, and whether whether correct and pipette tips end is located at correct hole slot position
Put, so as to ensure that the pipette tips of liquid-transfering gun 6 are in vertical position all the time, pipette tips can be avoided to insert adjacent hole slot.Due to the present patent application
Device use during, it is single adjustment pipette tips height and attitude, and orifice plate to be measured 4 all the time be in fixed static position, its
It is simple to operate, and the situation for inhaling adjacent hole by mistake can be avoided to occur.
Wherein, the diameter in the hole on porous plate 1 should be less than the diameter of the pipette tips afterbody of liquid-transfering gun 6, to ensure the rifle of liquid-transfering gun 6
Head is not fallen out when passing through porous plate 1, and porous plate 1 can be existing institute with hole arrangement with the hole number on orifice plate 4 to be measured
Any one in the quantity and hole formation system of use, such as 1536 (32 × 48) holes, 384 (16 × 24) holes or 96 (8 × 12)
It is hole in (4 × 3) hole of 24 (6 × 4) hole of hole 48 (8 × 6) hole 12 or 6 (3 × 2) holes, its bracket
The matrix form of arrangement.
Further, elevating mechanism 5 is scissor-type lifting mechanism, guide tracked rack-gear type elevating mechanism, worm and gear
One kind in formula elevating mechanism.Certainly in addition it can also be the elevating mechanism 5 of other structures, as long as lifting can be controlled flat
The level of platform 2 is moved up and down, on use which kind of elevating mechanism 5, the present embodiment is not limited this, specifically optionally and
It is fixed.
Further, a kind of perforated plate sampling height adjustor that second embodiment of the invention is provided, scissor-type liter
Descending mechanism include scissor arms turning end 511 and scissor arms sliding end 512, scissor arms turning end 511 be separately fixed on pedestal 3 and
On hoistable platform 2, scissor arms sliding end 512 is slidably connected with pedestal 3 and hoistable platform 2 respectively, and scissor-type lifting mechanism 5 is also
Including drive mechanism, drive mechanism is used to drive the level of scissor arms sliding end 512 being slidably connected on pedestal 3 to slide.
In the present embodiment, when the scissor arms sliding end 512 on pedestal 3 is moved, it can turn with the scissor arms on moving base 3
Moved end 511 is rotated, so as to drive the scissor arms sliding end 512 on hoistable platform 2 to move, while driving on hoistable platform 2
Scissor arms turning end 511 rotate, and then realize the purpose that hoistable platform 2 is lifted in vertical direction.By scissor arms turning end 511
The scissor arms 51 constituted with scissor arms sliding end 512 are not only convenient for assembling, and will not stop the lifting situation of hoistable platform 2,
Therefore it is easy to observe the situation in the hole slot 41 of the insertion orifice plate to be measured of the pipette tips of liquid-transfering gun 6, occurs with the situation for avoiding maloperation.
In order to improve the stability of the movement of hoistable platform 2, scissor-type lifting mechanism 5 includes two groups and is located at respectively on pedestal 3
The scissor arms turning end 511 and scissor arms sliding end 512 of relative both sides.
Further, drive mechanism includes cross bar 74, screw rod 76, first gear 77 and is intermeshed with first gear 77
Second gear 78, the number of teeth of first gear 77 is more than the number of teeth of second gear 78, and second gear 78 is coaxially fixed on screw rod 76
On, second gear 78 is also coaxially connected with vernier knob 72, and first gear 77 is coaxially connected with coarse adjustment knob 71, coarse adjustment knob 71
The lateral surface of pedestal 3 is respectively positioned on vernier knob 72, the scissor arms of both sides are slided respectively and on pedestal 3 at the two ends of cross bar 74
End 512 is connected, and cross bar 74, which is provided with spiral shell block 75, spiral shell block 75, is provided with screw thread, and screw rod 76 runs through spiral shell block 75, pedestal 3 by screw thread
Inside it is additionally provided with the first retaining mechanism for preventing screw rod 76 from freely rotating.By rotating coarse adjustment knob 71, drive screw rod 76 to rotate, enter
And make it that being threaded in the cross tube 74 of screw rod 76 moves, so that the sliding end of scissor arms 512 is moved, you can real
The lifting of existing hoistable platform 2, when the pipette tips of liquid-transfering gun 6 are close to whne suction range, can use vernier knob 72 instead to adjust height, treat
When reaching specified altitude assignment, locked by the first retaining mechanism, then can carry out imbibition operation.
Wherein, the sliding groove 31 of level can be set in the both sides of pedestal 3, and the two ends of cross bar 74 set internal thread, Ran Houtong
The end that slide bolt 79 is connected to cross bar 74 is crossed, the head diameter of slide bolt 79 should be greater than the groove width of sliding groove 31, and then
Ensure the stable movement of cross bar 74.
In addition, prevent that the first retaining mechanism that screw rod 76 is freely rotated from including the first ratchet 771 and the first ratchet 731, the
One ratchet 771 and first gear 77 are coaxially connected, and the first ratchet 731 can control to rotate by coaxially connected lock-button 73, when
When turning to the S location in Fig. 4, first gear 77 is in releasing orientation, when turning to L positions, and first gear 77 is in lock
Tight state.
Further, a kind of perforated plate sampling height adjustor that third embodiment of the invention is provided, guide tracked tooth
Bar gear type elevating mechanism includes lifting slider 522 and lifting support 521, and lifting support 521 is vertically arranged on pedestal 3, rises
Descending branch post 521 is provided with trapezoidal rails 525, and trapezoidal rails 525 are provided with tooth bar 526, and lifting slider 522 is provided with leads with trapezoidal
The 3rd gear 527 cooperated with tooth bar 526, the 3rd tooth are provided with the dovetail groove that rail 525 cooperates, lifting slider 522
Wheel 527 is coaxially connected with to be additionally provided with the first lifting knob 523, lifting slider 522 by first rotating shaft 5231 prevents the 3rd tooth
The second retaining mechanism that wheel 527 is freely rotated.
In the present embodiment, by the mutual cooperation of trapezoidal rails 525 and dovetail groove, it can effectively ensure that hoistable platform 2
Vertical shift, and stable movement, after hoistable platform 2 is lifted to specified altitude assignment, can be locked by the second retaining mechanism, with
Prevent that the situation that hoistable platform 2 falls from occurring.
Further, the second retaining mechanism includes dovetail groove holding out against the jackscrew 520 in trapezoidal rails 525, or including
Second ratchet 528 and the second ratchet 529, jackscrew 520 are horizontally set on the side wall of lifting slider 522, the second ratchet 528 and
Three gears 527 are coaxially connected, and the second ratchet 529 is arranged in lifting slider 522, and pawl axis 5241 is provided with lifting slider 522,
Pawl axis 5241 is coaxially connected with height hook knob 524, and the second ratchet 529, can be embedding by the rotation of height hook knob 524
Enter or depart from the second ratchet 529.
Wherein, one chamber can be set close to dovetail groove outside in lifting slider 522, jackscrew 520 runs through lifting slider
522 side wall, and end is pushed against on the side wall of chamber, by tightening jackscrew 520, you can dovetail groove sidewall 5211 is held out against
In trapezoidal rails 525, dovetail groove both sides that in addition can be on lifting slider 522 set a jackscrew 520 respectively, in order to user
Selection is used.
Two are set in addition, can respectively be set in the both sides of the 3rd gear 527 on second ratchet 528, pawl axis 5241
Individual and one-to-one second ratchet 529 of the second ratchet 528, to ensure the stability of its height locking.
Further, a kind of perforated plate sampling height adjustor that four embodiment of the invention is provided, worm and gear
Formula elevating mechanism includes being vertically arranged with lifting support 534 on intermeshing worm gear 533 and worm screw 531, pedestal 3, lifting branch
Cylinder slotted eye 535 is provided with seat 534, worm screw 531 is vertically arranged in the cylinder slotted eye 535 in lifting support 534, worm screw 531
Upper end and hoistable platform 2 connect, worm gear 533 is provided with lifting support 534, the both sides of worm gear 533 pass through the second rotating shaft respectively
536 are coaxially connected with second lifting knob 532.Wherein, connector can be set in the bottom of hoistable platform 2, and worm screw 531 is led to
Connector is crossed to be attached with hoistable platform 2.
For the ease of placing orifice plate 4 to be measured, pedestal 3 is provided with limiting section 32, and limiting section 32 is used to ensure the He of orifice plate 4 to be measured
Hole position on porous plate 1 is corresponded.Wherein limiting section 32 can be position-limit mechanism or spacing mark.
Further, porous plate 1 is provided with handle 12.Wherein handle 12 can be to be arranged on the porous side of plate 1
The concave surface of certain radian can be set on projection, projection, in order to for push-and-pull.In addition the handle 12 should be arranged on porous plate 1
On the side that is not in contact with hoistable platform 2.
Further, porous plate 1 is transparent porous plate 1, and it can be made up of clear perspex material.
Further, hoistable platform 2 is transparent hoistable platform 2, and it can be made up of clear perspex material.
Further, 500uL water and 500uL isoamyl acetates are loaded as sampling target using 96 (8 × 12) hole depth orifice plates,
Carry out determining height sampling 300uL to isoamyl acetate layer with 1mL Multi-channel liquid transfer devices, it is many described in present application example one to four
Orifice plate sampling height adjustor, which can be rapidly completed, determines height sampling, errorless water accepting layer, while errorless inhale adjacent hole.As a comparison,
Identical sampling is carried out using commercially available closed and regulation podium level mode perforated plate sampling height adjustor, because 1mL is more
The lengthening suction nozzle that channel pipettor is matched somebody with somebody there is certain curvature in it, and suction nozzle mouth is not fully in same straight line, in operating process
Mistake in the presence of 5% pair of adjacent hole inhales generation.
It should also be noted that, herein, such as first and second or the like relational terms are used merely to one
Entity or operation make a distinction with another entity or operation, and not necessarily require or imply between these entities or operation
There is any this actual relation or order.Moreover, term " comprising ", "comprising" or its any other variant are intended to contain
Lid nonexcludability is included, so that process, method, article or equipment including a series of key elements not only will including those
Element, but also other key elements including being not expressly set out, or also include being this process, method, article or equipment
Intrinsic key element.In the absence of more restrictions, the key element limited by sentence " including one ... ", it is not excluded that
Also there is other identical element in the process including the key element, method, article or equipment.
The embodiment of each in this specification is described by the way of progressive, and what each embodiment was stressed is and other
Between the difference of embodiment, each embodiment identical similar portion mutually referring to.
The foregoing description of the disclosed embodiments, enables professional and technical personnel in the field to realize or using the present invention.
A variety of modifications to these embodiments will be apparent for those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, it is of the invention
The embodiments shown herein is not intended to be limited to, and is to fit to and principles disclosed herein and features of novelty phase one
The most wide scope caused.
Claims (10)
1. a kind of perforated plate sampling height adjustor, it is characterised in that including:Porous plate, hoistable platform, pedestal and treat gaging hole
The elevating mechanism that plate and the control hoistable platform are moved up and down, the porous plate level is plugged on the hoistable platform
On, the hole position of the porous plate is used for fixed liquid-transfering gun pipette tips vertically, and the orifice plate to be measured is arranged on the pedestal, described
Porous plate is located at the surface of the orifice plate to be measured, and a pair of hole position 1 on the porous plate and the orifice plate to be measured
Should.
2. perforated plate sampling height adjustor according to claim 1, it is characterised in that the elevating mechanism is scissor-type
One kind in elevating mechanism, guide tracked rack-gear type elevating mechanism, Worm-gear type elevating mechanism.
3. perforated plate sampling height adjustor according to claim 2, it is characterised in that the scissor-type lifting mechanism bag
Scissor arms turning end and scissor arms sliding end are included, the scissor arms turning end is separately fixed on the pedestal and the lifting is flat
On platform, the scissor arms sliding end is slidably connected with the pedestal and the hoistable platform respectively, the fork type elevator
Structure also includes drive mechanism, and the drive mechanism is used to drive the scissor arms sliding end water being slidably connected on the pedestal
It is smooth dynamic.
4. perforated plate sampling height adjustor according to claim 3, it is characterised in that the scissor-type lifting mechanism bag
Include two groups of scissor arms turning end and the scissor arms sliding end for being located at both sides relative on the pedestal respectively.
5. perforated plate sampling height adjustor according to claim 4, it is characterised in that the drive mechanism includes horizontal stroke
Bar, screw rod, first gear and and the intermeshing second gear of the first gear, the number of teeth of the first gear is more than institute
The number of teeth of second gear is stated, the second gear is coaxially fixed on the screw rod, and the second gear is also coaxially connected with micro-
Knob is adjusted, the first gear is coaxially connected with coarse adjustment knob, and the coarse adjustment knob and the vernier knob are respectively positioned on the base
The lateral surface of seat, the scissor arms sliding end of both sides is connected respectively and on the pedestal at the two ends of the cross bar, described
Cross bar, which is provided with spiral shell block, the spiral shell block, is provided with screw thread, and the screw rod is run through in the spiral shell block, the pedestal by the screw thread
It is additionally provided with the first retaining mechanism for preventing the screw rod from freely rotating.
6. perforated plate sampling height adjustor according to claim 2, it is characterised in that the guide tracked rack-gear type
Elevating mechanism includes lifting slider and lifting support, and the lifting support is vertically arranged on the pedestal, the lifting support
Trapezoidal rails are provided with, the trapezoidal rails are provided with tooth bar, and the lifting slider is provided with and the trapezoidal rails phase interworking
The dovetail groove of conjunction, is provided with the lifting slider and the 3rd gear that the tooth bar cooperates, and the 3rd gear passes through the
One rotating shaft is coaxially connected with for being additionally provided with the first lifting knob, the lifting slider and preventing the 3rd gear from freely rotating
Two retaining mechanisms.
7. perforated plate sampling height adjustor according to claim 6, it is characterised in that second retaining mechanism includes
The dovetail groove is held out against into the jackscrew in the trapezoidal rails, or including ratchet and pawl, the jackscrew is horizontally set on institute
State on the side wall of lifting slider, the ratchet and the 3rd gear are coaxially connected, and the ratchet is arranged on the lifting slider
It is interior, pawl axis is provided with the lifting slider, the pawl axis is coaxially connected with height hook knob, and the ratchet passes through described
The rotation of height hook knob, can be embedded in or depart from the ratchet.
8. perforated plate sampling height adjustor according to claim 2, it is characterised in that the Worm-gear type lift
Structure includes being vertically arranged with intermeshing worm gear and worm screw, the pedestal in lifting support, the lifting support provided with circle
Post slotted eye, the worm screw is vertically arranged in the cylinder slotted eye in the lifting support, the upper end of the worm screw and the lifting
Platform is connected, and worm gear is provided with the lifting support, the both sides of the worm gear are coaxially connected with one by the second rotating shaft respectively
Second lifting knob.
9. the perforated plate sampling height adjustor according to any one of claim 1 to 8, it is characterised in that the lifting is put down
Platform and/or the porous plate are transparent hoistable platform and/or transparent porous plate.
10. perforated plate sampling height adjustor according to claim 9, it is characterised in that the pedestal is provided with spacing
Portion, the limiting section is used to ensure that the hole position on the orifice plate to be measured and the porous plate to be corresponded.
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CN110694705A (en) * | 2019-10-14 | 2020-01-17 | 山东省化工研究院 | Liquid feeding and taking device convenient for U-shaped porous glass plate absorption tube |
CN113176166A (en) * | 2021-04-26 | 2021-07-27 | 安徽工程大学 | Magnetic fluid sample magnetic field intensity adjusting device and using method |
CN114939452A (en) * | 2022-07-25 | 2022-08-26 | 北京凯祥弘康生物科技有限公司 | Subassembly is placed to consumptive material for it is biological experiments |
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Application publication date: 20170718 |