CN108490202A - A kind of automatic detection device of medicine sample - Google Patents
A kind of automatic detection device of medicine sample Download PDFInfo
- Publication number
- CN108490202A CN108490202A CN201810309096.8A CN201810309096A CN108490202A CN 108490202 A CN108490202 A CN 108490202A CN 201810309096 A CN201810309096 A CN 201810309096A CN 108490202 A CN108490202 A CN 108490202A
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- Prior art keywords
- suction nozzle
- slide
- sampling
- detection device
- automatic detection
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The invention discloses a kind of automatic detection devices of medicine sample, including sample transport apparatus, photographic means, dilution device, sampler and detection device；The sampler includes sampling position, smear position；The sampler includes the suction mechanism that position control mechanism and sampling suction nozzle and the sampling suction nozzle by being connected are drawn and filled；The position control mechanism is selectively connect with the sampling suction nozzle, include with it is described sampling suction nozzle connection take suction nozzle position and with it is described sampling suction nozzle detach go to suction nozzle position.The sampling suction nozzle that the technical solution passes through a simple optional connection structure, so that detection device realizes a sexual function of sampling when carrying out automation sample detection, in preferably realization device versatility, the technical issues of being easy to efficiently solve detection device self-pollution and sample cross contamination on the basis of popularizing.The technical program has simple in structure, easy to implement, the promotion and popularization effect with preferable automatic detection device.
Description
Technical field
The present invention relates to a kind of medicine sample testing apparatus, more particularly to a kind of for the automatic of excrement class medicine sample
Detection device.
Background technology
The detection of excrement sample, it is used at present square such as the chemical detection of stool routine examination detection and part excrement sample
Method is all relatively backward.From sample collect sample operation inspection and last sample liquid waste processing easily causes environment
With the pollution in laboratory.And the prevalence in order to keep off infection, the cotton swab for the collect specimen that patient is used, the object for holding sample
Product will carry out specially treated, and the link of processing is more, and the probability polluted is higher, in checking operating process, also very
It is unhygienic.With the progress of medical diagnosis and treatment technology, basis checks the necessary links for having become the diagnosis state of an illness.Three is big conventional
One of excrement detection, requirements at the higher level also proposed to detection efficiency, accuracy, resulting number and working environment.Bulletin
Number a kind of automatic detection instrument for excrement sample is disclosed for the Chinese invention patent of CN101487845B, it includes with lower part：From
Movement controller；Dilution device, for quantitative dilution to be added into excrement sample；Stirring and evenly mixing device, for after diluting
Excrement sample stirs and evenly mixs；Detection unit, for being detected to excrement sample；Sample and cleaning device are inhaled, pipeline and institute are passed through
It states detection unit to be connected, for conveying excrement sample to detection unit, and cleans detection unit and connection after detection
Pipeline.And the Chinese invention patent that notification number is CN104049095B discloses a kind of excrement detector, it includes pedestal, gantry
Frame component, Automatic-feeding component, sample conveyer system including chuck component, Suction cup assembly, the first liquid-adding device, the second liquid feeding
Device, the first photographic means, the second photographic means, identification and record system, electric control system and upper layer human-computer interaction are answered
Use software.Excrement detector coordinating operation under the allotment of control system is fully automatically completed to promote, take from the automatic of sample
Sample applies sample, microphotograph, occult blood reaction photograph and recycles whole process automatically, and carried by upper layer human-computer interaction application software
For testing result.For another example the Chinese invention patent that notification number is CN104897911B discloses one kind and being automatically brought into operation stool examination
Instrument.It includes the biomicroscope being fixed on the chassis, sample sampling device, special inspection two way slide lane, special checking device, glass
Sheet devices, Five-channel sampling probe and Y-direction Z-direction manipulator, can automatic sampling, film-making, it is automatic to clean, automatic interpretation spy inspection as a result,
The automatic special inspection consumptive material of recycling, microscope automatically scanning, auto-focusing, automatic lock image, selectivity are left and taken photo information, are printed
Picture and text survey report.The above-mentioned prior art has made favorable attributes to detecting automatically, but also increases answering for equipment mechanism simultaneously
Polygamy substantially increases the cost of device, and detection device is made to be difficult to popularize, and is unfavorable for improving existing complete using manual operation
Defect.The problem of especially above-mentioned prior art has ignored detection device self-pollution or the pollution in order to reduce itself
The complexity for increasing to degree apparatus structure, increases unnecessary cost.As the excrement sample of CN101487845B is examined automatically
It surveys instrument to need to clean sampler after sampling, not only mechanism is complicated, and process is loaded down with trivial details, and cleaning can not have completely
Effect solves the problems, such as self-pollution or sample cross contamination.And the excrement detector of CN104049095B then need one it is dedicated
Sample kit carrys out the problem of solving device self-pollution, causes the use cost of device to increase, keeps popularization and application more unfavorable.
Invention content
It is an object of the present invention to provide a kind of automatic detection devices of medicine sample, simple optional by one
The sampling suction nozzle of connection structure so that detection device realizes a sexual function of sampling when carrying out automation sample detection,
Preferably realization device versatility efficiently solves detection device at least the above and/or defect on the basis of being easy to universal,
And provide the advantages of at least will be described later.
The technical solution adopted by the present invention is：A kind of automatic detection device of medicine sample, including sample transport apparatus, photograph
Phase device, dilution device, sampler and detection device；The sampler includes sampling position, smear position；The sampler
The suction mechanism for being drawn and being filled including position control mechanism and sampling suction nozzle and the sampling suction nozzle by being connected；It is described
Position control mechanism is selectively connect with the sampling suction nozzle, include with it is described sampling suction nozzle connect take suction nozzle position and with institute
That states sampling suction nozzle separation goes to suction nozzle position.The sampling suction nozzle that the technical solution passes through a simple optional connection structure so that
Detection device realizes a sexual function of sampling when carrying out automation sample detection, in preferably realization device versatility, easily
The technical issues of detection device self-pollution and sample cross contamination being efficiently solved on the basis of universal.The technical program has
There is simple in structure, easy to implement, the promotion and popularization effect with preferable automatic detection device.
Preferably, being equipped with a suction nozzle case assembly at suction nozzle position in described take；The suction nozzle case assembly includes depositing suction nozzle work
Position and take suction nozzle station；It is described deposit suction nozzle station to take suction nozzle station in overturning transmit.Sampling suction nozzle is conveyed by conveying mechanism
To suction nozzle station is deposited, in sampling overturning of the suction nozzle by turnover bracket for depositing suction nozzle station end, sampling suction nozzle is made to be switched to
Connection opening upwards in end take suction nozzle station, and the connection of sampler is waited for take.
Preferably, being equipped with a suction nozzle case assembly at suction nozzle position in described take；The suction nozzle case assembly includes depositing suction nozzle work
Position takes suction nozzle station and makes the elastic element for taking suction nozzle station described in the sampling suction nozzle push-in deposited in suction nozzle station；It is described
Suction nozzle station is taken to be transmitted in rotation.Suction nozzle station is taken by rotation transfer structure, the positioning for sampling suction nozzle is more accurate, reliably
Property higher.
Specifically, the suction mechanism includes that the aspirating mechanism being arranged on the position control mechanism and setting are sampling
Diaphragm in suction nozzle；The aspirating mechanism includes suction tube and sucker rod.Further, the aspirating mechanism further includes that control is convex
Wheel.Sample is drawn by aspirating mechanism and the cooperation for setting septate sampling suction nozzle, can preferably reduce disposable sampling suction nozzle
Cost.
Specifically, the suction mechanism includes that the pressing mechanism being arranged on the position control mechanism and setting are sampling
The air bag of suction nozzle upper end.Although program suction mechanism is complex, sampling sucker structure is simple, relative to the interior diaphragm that sets
Sample suction nozzle, it is easier to process.
Specifically, the pressing mechanism includes the first cylinder, the First piston bar coordinated with first cylinder and passes through
The First piston bar outer end is pushed refers to bar in a pair of squeeze of scissor folding.
Preferably, being additionally provided with the slide dispensing devices for sending slide to the smear position；The slide dispensing devices packet
Slide dispensing band is included, the slide dispensing takes is uniformly provided with slide slot corresponding with the slide in interval.By being equipped with
The soft slide dispensing band of slide slot has simple in structure, the high advantage of reliability.
Technical solution of the present invention advantageous effect is to pass through the disposable sampling suction nozzle that connection may be selected and matched suction
Mechanism is noted, preferably solves the problems, such as cross contamination between detection device self-pollution and sample, meanwhile, what the present invention used
Technical solution have simple in structure, easy to implement, low manufacture cost, be more convenient for popularization and application the advantages of.
Description of the drawings
Fig. 1 is the structural schematic diagram of the embodiment of the present invention one.
Fig. 2 is the structural schematic diagram of sampler in the embodiment of the present invention one.
Fig. 3 is the structural schematic diagram of slide dispensing devices in the embodiment of the present invention one.
Fig. 4 is the structural schematic diagram of another suction nozzle case assembly in the embodiment of the present invention one.
Fig. 5 is the structural schematic diagram of sampler in the embodiment of the present invention two.
Fig. 6 is A-A cross-sectional views in Fig. 5.
Fig. 7 is B-B cross-sectional views in Fig. 5.
Fig. 8 is the structural schematic diagram of suction nozzle case assembly in the embodiment of the present invention two.
Wherein：Sample transport apparatus 1, sample fixed mechanism 12, photographic means 2, dilution device 3, takes sample conveyer belt 11
Sampling device 4, position control mechanism 41, transverse-moving mechanism 411, elevating mechanism 412, suction mechanism 42, clamping device 43, the second cylinder
431, second piston bar 432, clamping refer to bar 433, pressing mechanism 44, the first cylinder 441, First piston bar 442, squeeze refer to bar
443, aspirating mechanism 45, suction tube 451, sucker rod 452, control cam 453, sampling suction nozzle 46, air bag 461, diaphragm 462, suction nozzle
Case assembly 47 deposits suction nozzle station 471, takes suction nozzle station 472, elastic element 473, take suction nozzle position 48, remove suction nozzle position 49, slide point
Device 5, slide storage rack 51, slide dispensing band 52, slide slot 521, slide 53, rack 7, sample adapting table 71, sample is sent to hold
Connect position 81, position 82 of taking pictures, water filling dilution position 83, sampling position 84, smear position 85, waste runner 9.
Specific implementation mode
Below by specific embodiment, and in conjunction with attached drawing, technical scheme of the present invention is further described.It needs
It is noted that under the premise of not colliding, it can be arbitrary between various embodiments described below or between each technical characteristic
Combination forms new embodiment.
Referring to Fig. 1 and Fig. 2, a kind of automatic detection device of medicine sample, including rack 7, the sample that is arranged in rack 7
Transmission device 1, photographic means 2, dilution device 3, sampler 4 and detection device (not showing on figure).In the inlet of the rack 7
It is provided with sample adapting table 71, which is a lace conveying device, the sample transport apparatus in the present embodiment
1 initial position is located at the sample adapting table 71 and constitutes a part for the sample adapting table 71.The sample transport apparatus 1 it is defeated
It send band to be equipped with sample successively from section start to accept position 81, position 82 of taking pictures, water filling dilution position 83, sampling position 84, take 48 and of suction nozzle position
Go to suction nozzle position 49.Sample realizes different function on each working position and falls into waste runner 9 by the tail band of conveyer belt.Sample is being clapped
Sample appearance and worm's ovum etc. are carried out according to position 82 by photographic means 2 significantly to detect.Sample is dilute in the progress water filling of water filling dilution position 3
It releases to form the dilution for meeting detection.Sample after dilution is fixed simultaneously in sampling position 84 by sample fixed mechanism 12
Carry out Vibratory Mixing.
The sampler 4 includes position control mechanism 41, sampling suction nozzle 46 and carries out sample absorption by sampling suction nozzle 46
With the suction mechanism 42 of subsequent samples squeezing.The sampling suction nozzle 46 is disposable suction nozzle, and with suction mechanism 42 in optional
It connects with selecting.The position control mechanism 41 is equipped with the transverse-moving mechanism 411 of the elevating mechanism 412 and transverse shifting that move up and down.It should
Sampling suction nozzle 46 is obtained and is moved to sampling taking suction nozzle position 48 to be sampled device by the control of position control mechanism 41 movement
Position 84 is simultaneously sampled by suction mechanism 42.This take suction nozzle position 48 be equipped with suction nozzle case assembly 47.
The suction nozzle case assembly 47 include be specially that suction nozzle storage rack deposits suction nozzle station 471 and specially suction nozzle positioning box
Take suction nozzle station 472.In the present embodiment, which is transformed into and takes from depositing suction nozzle station 471 in a manner of gravity overturning
Suction nozzle station 472 has advantage simple in structure, at low cost.Referring to Fig. 4, which also has other embodiment party
Formula, in this embodiment, this takes suction nozzle station 472 to deposit the sampling on suction nozzle station 471 using the suction nozzle positioning box of a rotation
Suction nozzle 46 presses to suction nozzle positioning box by an elastic element 473.Under the action of elastic element 473, when in suction nozzle positioning box
Locating slot when being aligned with the sampling suction nozzle 46 deposited in suction nozzle station 471, receive the sampling suction nozzle 46 and be transmitted to take suction
Head position 84, waits for taking for sampler.In the present embodiment, which is a rectangular spring.Sampling suction nozzle 46 exists
This takes suction nozzle station 472 to realize the optional connection with suction mechanism 42.In the present embodiment, which is a suction
Mechanism 45, including suction tube 451, sucker rod 452 and control cam 453, and the diaphragm 462 that is arranged in sampling suction nozzle 46.
It is equipped with the opening being adapted to 451 lower end of suction tube with 46 upper end of sampling suction nozzle that the suction mechanism 42 is used cooperatively, diaphragm 462 is arranged
In the sampling suction nozzle 46 close to opening.The diaphragm 462 will sample suction nozzle 46 and be separated into two parts up and down, sample suction nozzle 46
Diaphragm 462 on part be adapted to the lower end of suction tube 451,462 lower part of diaphragm be used for draw sample.The pumping of the suction mechanism 42
Realize that push-and-pull of the sucker rod 452 in suction tube 451 is aspirated by controlling the cooperation of cam 453 in 452 top of soup stick.It should be appreciated that
In the aspirating mechanism 45, being additionally provided with makes 452 relation control cam 453 of sucker rod reset the resetting spring realized and extracted (on figure not
Show).Sampler 4 is moved to smear position 85 after obtaining sample by position control mechanism 41.The control cam 453 is equipped with suitable
Two parts with sampling position 84 and smear position 85.When sampling position 84, the sucker rod 452 in the suction mechanism 42 is resetting bullet
Uplink under the action of spring, generate suction force by sample suck sampling suction nozzle 46 and by diaphragm 462 be limited in sampling suction nozzle 46 every
Film 462 is in lower part.At smear position 85, downlink under the action of controlling cam 453 of sucker rod 452 will sample suction nozzle 46
In sample squeeze on slide 53.Slide 53 is distributed to the smear position 85 by slide dispensing devices 5 on the smear position 85.
Remaining sample is fallen by sample transport apparatus in waste runner 9.
Referring to Fig. 3, which includes that a slide storage rack 51 and a slide send band 52.The slide is sent
Band 52 is an annular endless conveyor.On slide dispensing band 52 slide slot 521 is evenly arranged in interval.The slide slot 521
Groove depth be slightly below the thickness of slide 53, the about one third of 53 thickness of slide to 2/3rds.Step motor control slide
52 intermittent movement of band is sent, the slide slot 521 on slide dispensing band 52, which is corresponding in turn to from 51 upper end opening of slide storage rack, to be taken out of
Slide 53.Sampler 4 is moved to suction nozzle position 49 after the slide 53 of 85 pairs of smear position dispensing in place carries out sample smear, and
In the separation for removing the realization of suction nozzle position 49 sampling suction nozzle 46.It should be appreciated that being additionally provided with detection device (on figure not in the smear position 85
Show), for being detected to the print on slide 53.It should be appreciated that this automatic detection device further include all devices of control or
Innovation main points in the control system (not showing on figure) of mechanism, the control system and non-present invention, in those skilled in the art institute
It is known to have all more options in the prior art.
Embodiment two
The present embodiment except in sampler suction mechanism 42 and the sampling suction nozzle 46 that is adapted to therewith it is different in addition to, remaining with
Embodiment one is identical.
Referring to Fig. 5, Fig. 6 and Fig. 7, in the present embodiment, the suction mechanism 42 in sampler 4 includes 43 He of clamping device
Pressing mechanism 44, and be arranged sampling 46 upper end opening of suction nozzle on air bag 461.The clamping device 43 and pressing mechanism 44 are equal
Using cylinder as actuating unit.The clamping device 43 is positioned at the main part of sampling suction nozzle 46, which is positioned at
At the air bag 461 of 46 upper end of sampling suction nozzle.The clamping device 43 includes the second cylinder 431, is arranged in the second cylinder 431
Second piston bar 432 and the clamping being hinged in pairs on the second cylinder 431 of 432 outer end both sides of second piston bar refer to bar 433.It should
The tail end that clamping refers to bar 433 is connected in the annular groove on 432 outer end of second piston bar.Second piston bar 432 is in pressure gas
Body effect is lower to push the tail end that the clamping refers to bar 433 by the annular groove of its outer end so that the clamping refers to bar 433 and carries out scissor open
It closes, and clamping of the front realization for referring to bar 433 to sampling suction nozzle 46 is clamped by this two.Similarly, which wraps
It includes the first cylinder 441, the First piston bar 442 being arranged in the first cylinder 441 and is hinged on 442 outer end of First piston bar in pairs
Extruding on first cylinder 441 of both sides refers to bar 443.The tail end that the extruding refers to bar 443 is connected to 442 outer end of First piston bar
On an annular groove in.First piston bar 442 pushes the extruding to refer to bar 443 under pressed gas effect by the annular groove of its outer end
Tail end so that the extruding refers to bar 443 and carries out scissor folding, and is squeezed by this two and refer to the realization of 443 front of bar to sampling suction
The extruding of first 46 upper end air bag 461.Referring to Fig. 8, in the present embodiment, the sampling suction nozzle 46 of the suction nozzle case assembly 47 is from depositing suction nozzle
Station 471 is directly pushed to by an elastic element 473 and takes suction nozzle station 472.In the present embodiment, this takes suction nozzle station 472
Using the suction nozzle positioning box of a rotational structure, which is a rectangular spring.Under the action of elastic element 473,
The sampling suction nozzle 46 deposited on suction nozzle station 471 presses to suction nozzle positioning box, when in suction nozzle positioning box a locating slot and deposit suction nozzle
When sampling suction nozzle 46 in station is aligned, receive the sampling suction nozzle 46 and be transmitted to take suction nozzle position 472, wait for and suction mechanism 42
Connection take.
Specific embodiment be for a clearer understanding of the present invention, not as a limitation of the rights of the invention,
Under the premise of not departing from present inventive concept, can there is a various variations, it is all these aobvious to the field technology personnel and
The modification being clear to is included within the scope of present claims.
Claims (10)
1. a kind of automatic detection device of medicine sample, including sample transport apparatus, photographic means, dilution device, sampler
And detection device；The sampler includes sampling position, smear position；It is characterized in that：The sampler includes position control
The suction mechanism that mechanism and sampling suction nozzle and the sampling suction nozzle by being connected are drawn and filled；The position control mechanism
Selectively connect with the sampling suction nozzle, include with it is described sampling suction nozzle connect take suction nozzle position and with the sampling suction nozzle divide
From go to suction nozzle position.
2. automatic detection device according to claim 1, it is characterised in that：A suction nozzle box are equipped at suction nozzle position in described take
Component；The suction nozzle case assembly includes depositing suction nozzle station and taking suction nozzle station；It is described deposit suction nozzle station to take suction nozzle station in turning over
Turn transmission.
3. automatic detection device according to claim 1, it is characterised in that：A suction nozzle box are equipped at suction nozzle position in described take
Component；The suction nozzle case assembly includes depositing suction nozzle station, taking suction nozzle station and the sampling suction nozzle deposited in suction nozzle station is made to push away
Enter the elastic element for taking suction nozzle station；It is described that suction nozzle station is taken to be transmitted in rotation.
4. automatic detection device according to claim 1 or 2 or 3, it is characterised in that：The suction mechanism includes that setting exists
Aspirating mechanism on the position control mechanism and the diaphragm being arranged in sampling suction nozzle；The aspirating mechanism includes suction tube and pumping
Soup stick.
5. automatic detection device according to claim 4, it is characterised in that：The aspirating mechanism further includes control cam.
6. automatic detection device according to claim 1 or 2 or 3, it is characterised in that：The suction mechanism includes that setting exists
Pressing mechanism on the position control mechanism and the air bag in sampling suction nozzle upper end is set.
7. automatic detection device according to claim 6, it is characterised in that：The pressing mechanism include the first cylinder, with
The First piston bar and pushed by the First piston bar outer end crowded in a pair of scissor folding that first cylinder coordinates
Pressure refers to bar.
8. automatic detection device according to claim 1 or 2 or 3, it is characterised in that：It is additionally provided with to the smear position and sends
The slide dispensing devices of slide；The slide dispensing devices include that a slide sends band, and the slide dispensing takes equal in interval
It is even to be equipped with slide slot corresponding with the slide.
9. the excrement automatic detection device according to right 4, it is characterised in that：It is additionally provided with to the smear position and sends slide
Slide dispensing devices；The slide dispensing devices include that a slide sends band, and the slide dispensing takes to be uniformly provided in interval
Slide slot corresponding with the slide.
10. the excrement automatic detection device according to right 6, it is characterised in that：It is additionally provided with to the smear position and sends slide
Slide dispensing devices；The slide dispensing devices include that a slide sends band, and the slide dispensing takes uniformly to be set in interval
There is slide slot corresponding with the slide.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810309096.8A CN108490202A (en) | 2018-04-09 | 2018-04-09 | A kind of automatic detection device of medicine sample |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810309096.8A CN108490202A (en) | 2018-04-09 | 2018-04-09 | A kind of automatic detection device of medicine sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108490202A true CN108490202A (en) | 2018-09-04 |
Family
ID=63315218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810309096.8A Pending CN108490202A (en) | 2018-04-09 | 2018-04-09 | A kind of automatic detection device of medicine sample |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108490202A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110567761A (en) * | 2019-10-08 | 2019-12-13 | 全椒先奇医药科技有限公司 | Assay sample collection device for hospital |
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| JP2010271315A (en) * | 2009-05-25 | 2010-12-02 | F Hoffmann-La Roche Ag | System and method for dispensing fluid |
| CN104897911A (en) * | 2014-07-02 | 2015-09-09 | 王佳能 | Automatically-operating stool examination instrument |
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Application publication date: 20180904 |