CN107831321A - A kind of reagent card sample-adding and conveyer - Google Patents

A kind of reagent card sample-adding and conveyer Download PDF

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Publication number
CN107831321A
CN107831321A CN201711010708.5A CN201711010708A CN107831321A CN 107831321 A CN107831321 A CN 107831321A CN 201711010708 A CN201711010708 A CN 201711010708A CN 107831321 A CN107831321 A CN 107831321A
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China
Prior art keywords
reagent card
reagent
conveyer
push rod
sample
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Granted
Application number
CN201711010708.5A
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Chinese (zh)
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CN107831321B (en
Inventor
韩丹丹
崔建华
董理
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Jilin Provincial Unitary Biotechnology Ltd By Share Ltd
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Jilin Provincial Unitary Biotechnology Ltd By Share Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00277Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention discloses a kind of reagent card sample-adding and conveyer,Including base,Drive device,Reagent card loads release device and detection means,Drive device includes line slideway,Push rod and support frame,Line slideway is arranged on base,Support frame movement is arranged on line slideway,Push rod is arranged on the top of support frame,Reagent card, which loads release device, includes reagent cartridge and reagent card box loading pocket,Reagent cartridge includes being used for the box body and supporting plate for holding reagent card,The retractable bottom for being arranged on box body of supporting plate,The through hole for box body disengaging is provided with the side wall of reagent card box loading pocket,Fixed mount is provided with base,Reagent card box loading pocket and detection means are each attached on fixed mount,Push rod is arranged on the lower section of supporting plate,Support frame is located at the side that reagent card loads release device,Detection means is located at the opposite side that reagent card loads release device.Reagent card sample-adding and conveyer provided by the invention can avoid unnecessary pollution, ensure the accuracy of test result.

Description

A kind of reagent card sample-adding and conveyer
Technical field
The present invention relates to albumin detection technique field, more particularly to a kind of reagent card sample-adding and conveyer.
Background technology
ACR analyzers are microalbumin (albumin, Alb) and creatinine (creatinine, Cr) in detection human urine The specialized analyzer of content and its ratio.Albumin is functional protein important in human body, and it contains in urine under normal circumstances Measure extremely low, when impaired renal function, albumin on a small quantity or even can be appeared in largely in urine.Studies have shown that is by detecting in urine Microalbumin can find albuminuria in time, it is by the early screening conventionally used for diabetic nephropathy, in diabetes Diagnosis, treatment and the prognosis evaluation aspect of nephrosis play an important role.Creatinine is product of the muscle in human body metabolism, no life Manage function.The generation of creatinine is more constant in blood under normal circumstances, mainly by kidney excretion into urine, therefore creatinine in urine Content is also relatively stable.
Clinical conventional diabetogenous nephrosis disease early diagnosis standard is measure twenty-four-hour urine at present or interval urine samples are micro overnight Albumin excretion rate, and the method have leave and take trouble, it is time-consuming the shortcomings that.It is demonstrated experimentally that using ACR analysis methods (Urine proteins/ Urine creatinine determines) take urina sanguinis or random urine to can be used to detect urinary protein excretion situation.With urine ACR methods measure microalbumin Urine, its result have good correlation with " goldstandard " Urinary Microalbumin Excretion rate and the quantitative determination of 24h urinary albumins, demonstrate,proved Real microdose urine protein can accurately reflect kidney albumin excretion amount with urine creatinine ratio, can be used as nephrosis early stage The sensitive indicator of injury of kidney.
Current dry type reagent card detection device is mostly that urine specimen artificially is added into reagent card, is put into equipment and detects, But because the uncontrollable factor of manual operation is a lot, it is easy to sample is polluted, causes testing result inaccurate, and Operating efficiency is low, it is impossible to continuous detection.
Therefore, how a kind of reagent card sample-adding and conveyer are provided, is current this area to ensure that testing result is accurate Technical staff's technical problem urgently to be resolved hurrily.
The content of the invention
It is an object of the invention to provide a kind of reagent card sample-adding and conveyer, to ensure that testing result is accurate.
In order to solve the above technical problems, the present invention provides following scheme:
A kind of reagent card sample-adding and conveyer, including base, drive device, reagent card load release device and detection dress Put, wherein,
The drive device includes line slideway, push rod and support frame, and the line slideway is arranged on the base, institute Being arranged on the line slideway for support frame movement is stated, the push rod is arranged on the top of support frame as described above,
The reagent card, which loads release device, includes reagent cartridge and reagent card box loading pocket, and the reagent cartridge includes using It is box-packed in the box body and supporting plate that hold reagent card, the retractable bottom for being arranged on the box body of the supporting plate, the reagent card The through hole being provided with the side wall in storehouse for box body disengaging is carried,
Fixed mount is provided with the base, the reagent card box loading pocket is fixed on the fixed mount, the detection Device is fixed on the fixed mount,
The push rod is arranged on the lower section of the supporting plate, and support frame as described above is located at one that the reagent card loads release device Side, the detection means are located at the opposite side that the reagent card loads release device.
Preferably, the first optoelectronic switch is provided with the side wall of above-mentioned line slideway, is set in the side wall of support frame as described above There is the catch being used cooperatively with first optoelectronic switch.
Preferably, above-mentioned push rod is strip sheet material, and the width of the push rod is more than the width of the reagent card, described to push away The groove for accommodating the reagent card is offered on bar.
Preferably, be provided with mentioned reagent cartridge loading pocket for detecting whether have the reagent card it is box-packed enter button Switch.
Preferably, mentioned reagent cartridge also includes dividing plate, and the dividing plate, which is built in the box body, is divided into two chambers Body, one of cavity are used to place drier, and another cavity is used to place the reagent card.
Preferably, multiple transverse concave grooves are provided with the inwall of mentioned reagent cartridge loading pocket, are provided with the box body Multiple horizontal boss, a horizontal boss dock with a transverse concave groove respectively.
Preferably, it is provided with spring top bead on the inwall of mentioned reagent cartridge loading pocket.
Preferably, it is provided with the outer wall of mentioned reagent cartridge loading pocket for detecting whether having the reagent card in gravity The second optoelectronic switch dropped under effect from the reagent cartridge on the push rod.
Preferably, above-mentioned detection device includes detection unit, temperature control equipment and the 3rd optoelectronic switch.
Preferably, gurry bucket is provided with above-mentioned base, the gurry bucket position is in the lower section of the detection means.
The reagent card sample-adding and conveyer that the invention described above is provided, including base, drive device, reagent card are loaded and released Device and detection means are put, wherein, the drive device includes line slideway, push rod and support frame, and the line slideway is set On the base, support frame as described above movement is arranged on the line slideway, and the push rod is arranged on support frame as described above Top, the reagent card, which loads release device, includes reagent cartridge and reagent card box loading pocket, and the reagent cartridge includes being used for Hold the box body and supporting plate of reagent card, the retractable bottom for being arranged on the box body of the supporting plate, the box-packed load of reagent card The through hole for box body disengaging is provided with the side wall in storehouse, fixed mount, the box-packed load of reagent card are provided with the base Storehouse is fixed on the fixed mount, and the detection means is fixed on the fixed mount, and the push rod is arranged on the supporting plate Lower section, support frame as described above are located at the side that the reagent card loads release device, and the detection means is located at reagent clamping Carry the opposite side of release device.
In use, pulling open supporting plate, reagent card declines on push rod from reagent cartridge, and now support frame moves up in line slideway It is dynamic, the reagent card on push rod is transported in detection means after sample is added and detected, can be avoided caused by artificial contact Unnecessary pollution, ensure the accuracy of test result, and improve operating efficiency.
Brief description of the drawings
Fig. 1 is the structural representation of reagent card provided in an embodiment of the present invention sample-adding and conveyer;
Fig. 2 is the backsight structural representation of drive device provided in an embodiment of the present invention;
Fig. 3 is the configuration schematic diagram that reagent card provided in an embodiment of the present invention loads release device;
Fig. 4 is the structural representation of detection means provided in an embodiment of the present invention.
In figure 1 above -4:
Drive device 1, line slideway 11, support frame 12, push rod 13, catch 14, the first optoelectronic switch 15, reagent card load Release device 2, reagent cartridge 21, reagent card box loading pocket 22, the second optoelectronic switch 23, key switch 24, reagent card 25, supporting plate 26th, detection means 3, detection unit 31, the 3rd optoelectronic switch 32, temperature control equipment 33, fixed mount 4, gurry bucket 5.
Embodiment
In order that those skilled in the art more fully understand the present invention program, below in conjunction with the accompanying drawings and it is embodied The present invention is described in further detail for mode.
Fig. 1-Fig. 4 is refer to, Fig. 1 is the structural representation of reagent card provided in an embodiment of the present invention sample-adding and conveyer Figure;Fig. 2 is the backsight structural representation of drive device provided in an embodiment of the present invention;Fig. 3 is examination provided in an embodiment of the present invention Agent clamps the configuration schematic diagram for carrying release device;Fig. 4 is the structural representation of detection means provided in an embodiment of the present invention.
The reagent card sample-adding and conveyer that the embodiment of the present invention is provided, including base, drive device 1, reagent clamp Release device 2 and detection means 3 are carried, wherein, drive device 1 includes line slideway 11, push rod 13 and support frame 12, line slideway 11 are arranged on base, and what support frame 12 moved is arranged on line slideway 11, such as is slided by sliding block and line slideway 11 Connection, push rod 13 are arranged on the top of support frame 12, and it is box-packed including reagent cartridge 21 and reagent card that reagent card loads release device 2 Carry storehouse 22, reagent cartridge 21 includes being used for holding the box body and supporting plate 26 of reagent card 25, supporting plate 26 it is retractable be arranged on box body Bottom, the through hole passed in and out for box body 21 is provided with the side wall of reagent card box loading pocket 22, fixed mount 4 is provided with base, Reagent card box loading pocket 22 is fixed on fixed mount 4, and detection means 3 is fixed on fixed mount 4, and push rod 13 is arranged on supporting plate 26 Lower section, support frame 12 are located at the side that reagent card loads release device 2, such as left side, and detection means 3 is located at reagent card loading and released Put the opposite side of device 2, such as right side.
In use, pulling open supporting plate 26, reagent card 25 declines on push rod 13 from reagent cartridge 21, and now support frame 12 is straight Moved on line guide rail 11, the reagent card 25 on push rod 13 is transported in detection means 3 after sample is added and detected, can be kept away Exempt from unnecessary pollution caused by artificial contact, ensure the accuracy of test result, and improve operating efficiency.
Wherein, multiple transverse concave grooves are provided with the inwall of reagent card box loading pocket 22, multiple transverse directions are provided with box body Boss, a horizontal boss dock with a transverse concave groove respectively.Two bullets are provided with the inwall of reagent card box loading pocket 22 The spring decorative pearl on top of an official cap.Be provided with reagent card box loading pocket 22 for detecting whether have reagent card it is box-packed enter key switch 24.Push rod 13 For strip sheet material, the width of push rod 13 is more than the width of reagent card 25, offered on push rod 13 for accommodating reagent card 25 Groove, groove can be a square openings.Gurry bucket 5 is provided with base, gurry bucket position is in the lower section of detection means 3.
The first optoelectronic switch 15 is provided with the side wall of line slideway 11, is provided with the side wall of support frame 12 and the first light The catch 14 that electric switch 15 is used cooperatively, it is provided with for detecting whether there is reagent card 25 on the outer wall of reagent card box loading pocket 22 The second optoelectronic switch 23 dropped under gravity from reagent cartridge 21 on push rod 13, it is single that detection means 3 includes detection Member 31, the optoelectronic switch 32 of temperature control equipment 33 and the 3rd.
When in use, it is necessary to which first reagent cartridge 21 is put into reagent card box loading pocket 22, two spring top beads will can try Agent cartridge 21 is fixed, and key switch 24 triggers;Now push rod 13 rests on initial position, does not have in the square opening of push rod 13 Reagent card 25, the state are monitored by the 3rd optoelectronic switch 32, also, catch 14 is entered in the crack of the first optoelectronic switch 15, Trigger the first optoelectronic switch 15;The lateral movement to the left of driving push rod 13 of line slideway 11, when the square opening on push rod 13 moves to examination During agent 21 underface of cartridge, twitch supporting plate 26, the reagent card 25 in reagent cartridge 21 under gravity, under fall on push rod 13 Square opening in;Push rod 13 continues to left movement, when square opening moves to the second 23 lower section of optoelectronic switch, is opened by the second photoelectricity Closing after whether thering is reagent card 25, confirmation to have in 23 monitoring square openings, push rod 13 continues to move to the position of addition sample to the left, After the completion of adding sample, push rod 13 moves right the position of detection means 3, and the reagent card 25 for having added sample is incubated And detect;After detection terminates, push rod 13, which continues to move right, returns to initial position, and reagent card 25 drops under gravity In gurry bucket 5, whether the detection reagent card 25 of the 3rd optoelectronic switch 32 has come off, and provides alarm, one reagent card 25 of completion Transmission and detection.
To sum up, the reagent card sample-adding and conveyer that the embodiment of the present invention is provided, it is only necessary to a line slideway 11, it is real Reagent card 25 is now automatically loaded, and reagent card 25 is sent to sample-adding position, is incubated position, detecting position, and the reagent completed will be detected In the gurry bucket 5 that card 25 abandons automatically, the efficiency of transmission and detection efficiency of reagent card 25 are substantially increased, while also there is structure Simply, dependable performance, processing and maintenance cost it is cheap the advantages that, can the extensive use in all kinds of dry type reagent card detection devices. It is a kind of continuous loading, transmission, detection and drop device of suitable high-volume dry type reagent card 25.
Wherein, if reagent cartridge 21 is put into loading pocket, key switch 24 is triggered, and the push rod 13 of reagent card 25 is carried out Transmission, on the contrary, during without reagent cartridge 21, key switch 24 is not triggered, and push rod 13 is failure to actuate.
Wherein, detection means 3 is internally provided with light source and amplifying circuit, is provided with Peltier and TEMP below Device and temperature control equipment 33, isoperibol is provided for detection means 3.In specific works, detection means 3 is an independence Part, on fixed mount 4.It is internally provided with the light source and amplifying circuit of two different wave lengths, to having added sample This reagent card 25 is detected in real time.Detection means 3 is also equipped with heating element heater and temperature sensor and temperature control equipment 33, temperature can be preset, reagent card 25 is detected under fixed isoperibol;The lower section of detection means 3 is provided with two Spring jackscrew, when reagent card 25 enters detection means 3, in the presence of jackscrew, reagent card 25 is tightly bonded detection means 3 Detection hole, light path interference is reduced, improves accuracy of detection.
Wherein, push rod 13 is plastic material, avoids push rod 13 that friction occurs when being driven and produces noise.Reagent cartridge 21 is also wrapped Dividing plate is included, dividing plate, which is built in box body, is divided into two cavitys, and one of cavity is used to place drier, another chamber Body is used to place reagent card 25.Drier can realize the drying to overall tray interior, avoid reagent card 25 from being lost because moist Effect.
Specific case used herein is set forth to the principle and embodiment of the present invention, and above example is said It is bright to be only intended to help the method and its core concept for understanding the present invention.It should be pointed out that the ordinary skill for the art For personnel, under the premise without departing from the principles of the invention, some improvement and modification, these improvement can also be carried out to the present invention Also fallen into modification in the protection domain of the claims in the present invention.

Claims (10)

1. a kind of reagent card sample-adding and conveyer, it is characterised in that load release dress including base, drive device, reagent card Put and detection means, wherein,
The drive device includes line slideway, push rod and support frame, and the line slideway is arranged on the base, the branch Support movement is arranged on the line slideway, and the push rod is arranged on the top of support frame as described above,
The reagent card, which loads release device, includes reagent cartridge and reagent card box loading pocket, and the reagent cartridge includes being used to contain Put the box body and supporting plate of reagent card, the retractable bottom for being arranged on the box body of the supporting plate, the reagent card box loading pocket Side wall on be provided with for the box body disengaging through hole,
Fixed mount is provided with the base, the reagent card box loading pocket is fixed on the fixed mount, the detection means It is fixed on the fixed mount,
The push rod is arranged on the lower section of the supporting plate, and support frame as described above is located at the side that the reagent card loads release device, The detection means is located at the opposite side that the reagent card loads release device.
2. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that in the side wall of the line slideway The first optoelectronic switch is provided with, the catch being used cooperatively with first optoelectronic switch is provided with the side wall of support frame as described above.
3. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that the push rod is elongated plates Material, the width of the push rod are more than the width of the reagent card, offered on the push rod for accommodating the recessed of the reagent card Groove.
4. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that on the reagent card box loading pocket Be provided with for detecting whether have the reagent card it is box-packed enter key switch.
5. reagent card according to claim 1 sample-adding and conveyer, it is characterised in that the reagent cartridge also include every Plate, the dividing plate, which is built in the box body, is divided into two cavitys, and one of cavity is used to place drier, and in addition one Individual cavity is used to place the reagent card.
6. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that the reagent card box loading pocket Multiple transverse concave grooves are provided with inwall, are provided with multiple horizontal boss on the box body, a horizontal boss respectively with One transverse concave groove docking.
7. reagent card sample-adding according to claim 6 and conveyer, it is characterised in that the reagent card box loading pocket Spring top bead is provided with inwall.
8. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that the reagent card box loading pocket It is provided with outer wall for detecting whether there is the reagent card to drop to described push away from the reagent cartridge under gravity The second optoelectronic switch on bar.
9. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that the detection means includes detection Unit, temperature control equipment and the 3rd optoelectronic switch.
10. reagent card sample-adding according to claim 1 and conveyer, it is characterised in that be provided with and abandon on the base Thing bucket, the gurry bucket position is in the lower section of the detection means.
CN201711010708.5A 2017-10-25 2017-10-25 Reagent card application of sample and conveyer Active CN107831321B (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108490202A (en) * 2018-04-09 2018-09-04 杭州杭睿科技有限公司 A kind of automatic detection device of medicine sample
CN108535502A (en) * 2018-04-09 2018-09-14 杭州杭睿科技有限公司 A kind of automatic detection device for medicine sample
CN109900891A (en) * 2019-04-22 2019-06-18 广西埃韦迪生物科技有限公司 A kind of medical rotary table formula entry colloid gold immune analyzer
CN110045111A (en) * 2019-06-03 2019-07-23 思库科技(广州)有限公司 A kind of mating detection device and detection method of dry type fluorescence/colloid gold reagent card
CN113406029A (en) * 2021-03-25 2021-09-17 江苏硕世生物科技股份有限公司 Detection result reading device

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CN104724454A (en) * 2013-12-24 2015-06-24 广州万孚生物技术股份有限公司 Reagent card settling transmission device
CN204439645U (en) * 2014-11-17 2015-07-01 基蛋生物科技股份有限公司 A kind of reagent strip stores and automatic pop-up device
CN205898829U (en) * 2016-07-27 2017-01-18 广州万孚生物技术股份有限公司 A advance to clamp and put for fluorescent quantitation analysis appearance
CN206540924U (en) * 2017-02-11 2017-10-03 深圳拓能达科技有限公司 A kind of automatic projecting reagent strip testing agency

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US6180409B1 (en) * 1998-10-13 2001-01-30 Bayer Corporation Spectrophotometric apparatus with multiple readheads
CN104345157A (en) * 2013-07-29 2015-02-11 广州万孚生物技术股份有限公司 Reagent card, reagent card case as well as detecting reagent suite
CN104724454A (en) * 2013-12-24 2015-06-24 广州万孚生物技术股份有限公司 Reagent card settling transmission device
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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108490202A (en) * 2018-04-09 2018-09-04 杭州杭睿科技有限公司 A kind of automatic detection device of medicine sample
CN108535502A (en) * 2018-04-09 2018-09-14 杭州杭睿科技有限公司 A kind of automatic detection device for medicine sample
CN109900891A (en) * 2019-04-22 2019-06-18 广西埃韦迪生物科技有限公司 A kind of medical rotary table formula entry colloid gold immune analyzer
CN110045111A (en) * 2019-06-03 2019-07-23 思库科技(广州)有限公司 A kind of mating detection device and detection method of dry type fluorescence/colloid gold reagent card
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CN113406029A (en) * 2021-03-25 2021-09-17 江苏硕世生物科技股份有限公司 Detection result reading device

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