CN104998230A - Traditional Chinese medicinal oral liquid for treating hyperuricemia, and preparation method thereof - Google Patents

Abstract

The invention discloses a traditional Chinese medicinal oral liquid for treating hyperuricemia, and a preparation method thereof. The oral liquid is prepared from, by weight, 6-10 parts of aconite root, 3-6 parts of Ampelopsis japonica, 3-6 parts of Ligusticum wallichii, 3-6 parts of cowry shell, 3-6 parts of Rhizoma Cimicifugae, 10-18 parts of Radix Angelicae Pubescentis, 3-5 parts of Radix Astragali, 5-10 parts of Glabrous Greenbrier Rhizome, 3-8 parts of chamomile flower, 5-10 parts of Cortex Acanthopanacis, 5-10 parts of Gentiana macrophylla, 3-8 parts of Divaricate Saposhnikovia Root, 2-5 parts of baked ginger, 2-4 parts of Herba Schizonepetae, 3-6 parts of wild jujube, 3-10 parts of Artemisia argyi, 5-10 parts of cherry and 5-10 parts of grape. The traditional Chinese medicinal oral liquid has the advantages of definite therapeutic effect, simple components, comprehensive conditioning, reasonable composition, effective reduction and prevention of high pH value of uric acid, reduction of patients' pains, stable quality, and no toxic side effects, and has effective prevention and treatment effects on gout, hypertension, diabetes and related diseases caused by high uric acid.

Description

A kind of Chinese medicine oral liquid and preparation method for the treatment of hyperuricemia

Technical field

The present invention relates to hyperuricemia Chinese medicine, especially provide and effectively reduce prevention metabolic arthritis pH value, reduce patient suffering; And determined curative effect, steady quality and a kind of Chinese medicine oral liquid and the preparation method for the treatment of hyperuricemia had no side effect.

Background technology

Hyperuricemia (HUA) refers under normal purine diet state, and non-twice fasting blood uric acid level male is higher than 420 μm of ol/L on the same day, and women, higher than 360 μm of ol/L, is namely called hyperuricemia.Uric acid is the end last metabolite of mankind's purine compound.Purine metabolic disturbance causes hyperuricemia.Primary disease prevalence is subject to the impact of many factors, relevant with heredity, sex, age, life style, dietary habit, Drug therapy and economic development level etc.According to the report of various places prevalence of hyperuricemia in recent years, about there is hyperuricemia person 1.2 hundred million in current China, accounts for 10% of total population, and the age occurred frequently is middle-aging male and postmenopausal women, but has rejuvenation trend in recent years.

Hyperuricemia is because uricopoiesis in body is too much and (or) caused by hypoecrisia, wherein can be divided into again constitutional and the large class of Secondary cases two.

1. primary hyperuricemia

(1) reason of underexcretion 90% primary gout patient hyperuricemia is relevant with underexcretion, and its mechanism has: 1. glomerular filtration reduces; 2. reabsorption increases; 3. tubular secretion reduces.

(2) uricopoiesis too much endogenous uric acid produces too much definition and is: at low purine diet (< 17.9 μm of ol/d), after 5 days, urine uric acid output is still greater than 3.58mmol.The reason of 10% primary gout patient hyperuricemia is too much relevant with uricopoiesis.Its mechanism may be that endogenous uricopoiesis is too much.Increase with some the enzyme quantity promoted in uricopoiesis process with active and (or) suppress the quantity of some enzymes of uricopoiesis and activity to reduce relevant.The defect of enzyme is relevant with genovariation, can be polygenes, also can be single-gene.Mode of inheritance can be divided into autosomal recessive, normal dyeing dominant inheritance and sex-linked inheritance.

2. secondary hyperuricemia

(1) kidney underexcretion 1. nephropathy such as Glomerular lesions cause uric acid filter reduce and renal tubules pathological changes cause uric acid secrete minimizing; 2. diuretic particularly thiazide diuretic, other drug such as aspirin, pyrazinamide, levodopa, ethambutol, ethanol etc. also can disturb renal tubules to the heavily absorption of uric acid; 3. in body, organic acid increases as keto acid, lactic acid contestable suppress the secretion of renal tubules uric acid.

(2) uric acid produces and is too much more common in bone marrow and lymphoproliferative disorders.In leukemia, lymphoma chemotherapy, Patients During Radiotherapy, due to a large amount of cytoclasises, nucleic acid metabolism can be caused to accelerate, and then cause secondary hyperuricemia.

So hyperuricemia can cause various disease conditions to occur, such as: gout, hypertension, diabetes etc., so control effectively to reduce uric acid pH value, reach in standard value range and be even more important, only have premised on prevention and control metabolic arthritis disease, could prevent to cause some epidemy diseases such as gout, Chinese medicine oral liquid is few for control metabolic arthritis medicine on the market at present, so market also urgently wishes that Chinese medicine can shift to an earlier date prevention and therapy metabolic arthritis disease, meet clinical practice.

Summary of the invention

The object of the invention is to effectively reduce prevention metabolic arthritis pH value, reduce patient suffering; Cause metabolic arthritis the associated conditions such as gout, hypertension, diabetes to have a kind of Chinese medicine oral liquid and preparation method for the treatment of hyperuricemia of effective prevention and therapy effect, meet the problem that above-mentioned background technology proposes.

To achieve these goals, the invention provides following technical scheme:

The Chinese medicine oral liquid for the treatment of hyperuricemia of the present invention, it is mixed with by the raw material of Chinese medicine of following weight parts: Radix Aconiti Lateralis Preparata 6 ~ 10 parts, Radix Ampelopsis 3 ~ 6 parts, Rhizoma Chuanxiong 3 ~ 6 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 3 ~ 6 parts, Rhizoma Cimicifugae 3 ~ 6 parts, Radix Angelicae Pubescentis 10 ~ 18 parts, the Radix Astragali 3 ~ 5 parts, Rhizoma Smilacis Glabrae 5 ~ 10 parts, Flos Chrysanthemi 3 ~ 8 parts, Cortex Acanthopancis 5 ~ 10 parts, Radix Gentianae Macrophyllae 5 ~ 10 parts, Radix Saposhnikoviae 3 ~ 8 parts, black Rhizoma Zingiberis Recens 2 ~ 5 parts, Herba Schizonepetae 2 ~ 4 parts, Ziziphi Spinosae 3 ~ 6 parts, Folium Artemisiae Argyi 3 ~ 10 parts, 5 ~ 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 5 ~ 10 parts.

As the further scheme of the present invention: preferred to be mixed with by the raw material of Chinese medicine of following weight parts: Radix Aconiti Lateralis Preparata 10 parts, Radix Ampelopsis 5 parts, Rhizoma Chuanxiong 5 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 5 parts, Rhizoma Cimicifugae 5 parts, Radix Angelicae Pubescentis 15 parts, the Radix Astragali 5 parts, Rhizoma Smilacis Glabrae 10 parts, Flos Chrysanthemi 5 parts, Cortex Acanthopancis 10 parts, Radix Gentianae Macrophyllae 5 parts, Radix Saposhnikoviae 6 parts, black Rhizoma Zingiberis Recens 3 parts, Herba Schizonepetae 4 parts, Ziziphi Spinosae 5 parts, Folium Artemisiae Argyi 10 parts, 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 10 parts.

Medical material used in the present invention has following characteristic:

Radix Aconiti Lateralis Preparata: [another name] Radix Aconiti Lateralis Preparata, Radix Aconiti Lateralis Preparata, Radix Aconiti Lateralis Preparata, Radix Aconiti Lateralis Preparata, [source] this product is the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx..[nature and flavor] are pungent, sweet, hot greatly; Poisonous.[return through] GUIXIN, kidney, spleen channel.[function cures mainly] recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.

Radix Ampelopsis: [another name] mountain region melon, wild Radix Ipomoeae, Vitis Amurensis seedling, Bletilla striata (Thunb.ex A.Murray)Rchb.f., Herba Rubi blinii, [source] this product is the dried root of vitaceae Radix Ampelopsis Ampelopsis japonica (Thunb.) Makino.[nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.

Rhizoma Chuanxiong: [nature and flavor] are pungent, temperature.[return through] returns liver, gallbladder, pericardium channel.[function cures mainly] blood-activating and qi-promoting, wind-expelling pain-stopping.

Monetariamoneta (L.)(Monetariaannulus (L.)): these product are few conventional Chinese medicine, have cowry shellwith Concha Erosariae seu Cypraeae two kinds.Cowry shell original name " Monetariamoneta (L.)(Monetariaannulus (L.)) ", the beginning is loaded in " sheng Nong's herbal classic", be classified as low-grades.[source] " herbal classic ", [Chinese name] Monetariamoneta (L.)(Monetariaannulus (L.)), [another name] shellfish tooth (" leigong Paozhilun"), white shellfish (" Japan hanako materia medica "), Bai Hai Ba (" easy folk prescription "), cowry shell(" medical material compilation of data").[source] is the shell of Cypraeidae animal Cypraeamoneta or ring grain Cypraeamoneta etc.Fish in seashore between 5 ~ July, except fleshing, clean and dry.[nature and flavor] are salty, cool. and 1. " herbal classic ": salty in the mouth, flat.2. " Japan hanako materia medica ": cool.[function cures mainly]

Heat clearing away, diuresis.The cold and heat that cure the wound are mad, aqueous vapor edema, drench pain hematuria, urinary obstruction, nasal sinusitis pus and blood, corneal nebula, dysentery.

Rhizoma Cimicifugae: [another name] big cattle card holder, Radix Longan, hole root of the tooth, [source] this product is ranunculaceae plant C.heracleifolia Cimicifuga heracleifolia Kom., Cimicifuga Dahurica Cimicifuga dahurica (Turcz.) Maxim. or the dry rhizome of Rhizoma Cimicifugae Cimicifuga foetida L..Autumn excavates, and removing silt, shines when doing to fibrous root, burn or remove fibrous root, drying.[character] this product is irregular microscler bulk, multi-branched, in nodositas, and long 10 ~ 20cm, diameter 2 ~ 4cm.[nature and flavor] are pungent, micro-sweet, are slightly cold.[return through] returns lung, spleen, stomach, large intestine channel.[function cures mainly] delivers rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy.

Radix Angelicae Pubescentis: [another name] fragrant Radix Angelicae Pubescentis, meat Radix Angelicae Pubescentis, RADIX ANGELICAE PUBESCENTIS from Sichuan of China, money mound Radix Angelicae Pubescentis, [source] this product is the dry root of samphire Angelica pubescens Angelica pubescens Maxim. f. biserrata Shan et Yuan.[nature and flavor] are pungent, bitter, tepor.[return through] returns kidney, urinary bladder channel.[function cures mainly] expelling wind and removing dampness, numbness relieving and pain relieving.

The Radix Astragali: [source] this product is the dry root of leguminous plant Radix Astagali Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao or Radix Astragali Astragalus membranaceus (Fisch.) Bge..[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.

Rhizoma Smilacis Glabrae: [source] this product is the dry rhizome of liliaceous plant smilacis glabra Smilax glabra Roxb..[nature and flavor] are sweet, light, flat.[return through] returns liver, stomach warp.[function cures mainly] dehumidifies, removing toxic substances, easing joint movement.For damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, bones and muscles pain.[extracts] " Chinese Pharmacopoeia ".

Delicately fragranced: chrysanthemum of every one hundred. Since the stem leaf colors. Different springtime delights. Leaves simple flowers small, yellow and green. Leaves color depth is small and thin. Should wait and is also in September. The opinion white chrysanthemum leaf is also used as a medicine. More than all the medical classics. Its stem has the different plant shoots purplish red green. Laid a thick thin tip of bald size. The flowers are chiba simple. Unintentional it. There are no children. Yellow and red purple three shades of different sizes. The taste is bitter. Of Xia Ju lanqiu chrysanthemum chrysanthemum of winter. Generally only with simple taste sweet medicine. Chrysanthemum spectrum carries the chamomile, opinion, the opinion is also white. [smells] flat non-toxic. And bitter cold. Can fall as well as rise. Yin in Yang also. Yellow into the goldwater Yin points. White into the goldwater Yang points. Red blood line woman points. Cover the earthy and gold are water and fire.

[curing mainly] all dizziness due to wind swell and ache. and order is for de-lacrimation. the dead flesh of skin. aversion to wind arthralgia chiefly caused by damp pathogen. take sharp vim and vigour for a long time. to make light of one's life by commiting suicide and resistance toly always to prolong life. nourishing YIN blood supports order the liver benefiting wood. all urticaria with it of dispelling. order takes off lacrimation. and top capping water is so system fire. and benefit gold is so flat wood. the flat gastric qi of then speaking sarcastically of wood. i.e. open country flos Chrysanthemialso. yellow skin and little. the heart is as Semen Nelumbinis. control carbuncle furunculosis scrofula.

Cortex Acanthopancis: [another name] CORTEX ACANTHOPANACIS, Radix Et Caulis Acanthopanacis Senticosi, thorn five first, [source] this product is the dry root bark of Araliaceae acanthopanax gracilistylus Acanthopanax gracilistylus W.W. Smith.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, kidney channel.[function cures mainly] wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening.

Radix Gentianae Macrophyllae: [another name] gentiana straminea, Gentiana dahurica, Radix Gentianae Marcrophyllae, western Radix Gentianae Marcrophyllae, a left side are turned round, a left side is twisted, RADIX GENTIANAE MACROPHYLLAE, RADIX GENTIANAE MACROPHYLLAE, Radix Raphani Macrophylla, plait Macrophylla, [character] Radix Gentianae Macrophyllae: cylindrical in class, upper coarse and lower fine, distortion is straight, long 10 ~ 30cm, diameter 1 ~ 3cm.[nature and flavor] are pungent, bitter, flat.[return through] returns stomach, liver, gallbladder meridian.[function cures mainly] wind-damp dispelling, clearing away damp-heat, stopping numbness pain.

Radix Saposhnikoviae: [nature and flavor] acrid, sweet, warm.[return through] returns bladder, liver, spleen channel.[function cures mainly] inducing diaphoresis to dispel wind, victory is wet, relieving convulsion.

Black Rhizoma Zingiberis Recens: be rhizoma Zingiberispreparation process product, [nature and flavor] are bitter, pungent, temperature.[function cures mainly] expelling wind and removing dampness, reducing swelling and alleviating pain.

Herba Schizonepetae: [another name] fragrant Schizonepeta tenuifolia Briq, line shepherd's purse, Herba Schizonepetae, false Soviet Union, [source] this product is the dry aerial parts of labiate Herba Schizonepetae Schizonepeta tenuifolia Briq..[nature and flavor] are pungent, tepor.[return through] returns lung, Liver Channel.

[function cures mainly] induces sweat loose wind, rash.

Ziziphi Spinosae: Ziziphi Spinosae (formal name used at school: Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chow) have another name called sour jujube, sour jujube, wild Fructus Jujubae, Fructus Choerospondiatis, Pueraria lobota pin etc., originate in North China, also there is distribution Central-South each province.Abnormal smells from the patient: (Ziziphi Spinosae) is sour, flat, nontoxic.Its sweet in the mouth, property is put down; Cure mainly: there is tonifying liver, mind calming, arresting sweating, the effect of promoting the production of body fluid; Cure mainly restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin void is thirsty waits disease.

Folium Artemisiae Argyi: [another name] Chinese mugwort, Radix Artemisia ordosicae, family Chinese mugwort, [source] this product is the dried leaves of feverfew Chinese mugwort Artemisia argyi Levl. et Vant..[nature and flavor] are pungent, bitter, temperature; Slightly poisonous.[return through] returns liver,spleen,kidney warp.[function cures mainly] dispersing cold for relieving pain, warming the meridian for stopping bleeding.

Fructus Pruni pseudocerasi: [another name] cherry apple (" Book of Rites "), Jing Tao (" elegant "), Zhu Ying (" another name for Sichuan Province is all composed "), Zhu fruit (" product remittance essence is wanted "), cherry pearl, family's Fructus Pruni pseudocerasi (" Chinese tree taxonomy ").[source] is the fruit of rosaceous plant Fructus Pruni pseudocerasi.[nature and flavor] are sweet, temperature, 1. " not Lu ": " sweet in the mouth." [function cures mainly] QI invigorating, wind-damp dispelling.Be in harmony paralysis, extremity are meciless, rheumatic lumbocrural pain pain, chilblain.

Fructus Vitis viniferae: [nature and flavor]: sweet; Acid; Flat.[return through]: enter lung, spleen, kidney channel.Fill blood; Bone and muscle strengthening; Diuresis.Main deficient qi and blood; Cough due to deficiency of the lung; Palpitation and night sweat; Excessive thirst; Rheumatic arthralgia; Gonorrhea; Pneumonedema; Varioliform exanthema is not saturating.

The present invention also provides the preparation method of above-mentioned Chinese medicine oral liquid, and the method usually adopting people to know in the art comprises the steps:

1) following weight parts proportioning raw material of Chinese medicine is taken: Radix Aconiti Lateralis Preparata 6 ~ 10 parts, Radix Ampelopsis 3 ~ 6 parts, Rhizoma Chuanxiong 3 ~ 6 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 3 ~ 6 parts, Rhizoma Cimicifugae 3 ~ 6 parts, Radix Angelicae Pubescentis 10 ~ 18 parts, the Radix Astragali 3 ~ 5 parts, Rhizoma Smilacis Glabrae 5 ~ 10 parts, Flos Chrysanthemi 3 ~ 8 parts, Cortex Acanthopancis 5 ~ 10 parts, Radix Gentianae Macrophyllae 5 ~ 10 parts, Radix Saposhnikoviae 3 ~ 8 parts, black Rhizoma Zingiberis Recens 2 ~ 5 parts, Herba Schizonepetae 2 ~ 4 parts, Ziziphi Spinosae 3 ~ 6 parts, Folium Artemisiae Argyi 3 ~ 10 parts, 5 ~ 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 5 ~ 10 parts;

2) above-mentioned raw material of Chinese medicine soak by water secondary, each water consumption is the 8-10 times amount of medical material weight, decocts secondary, each l-2 hour, filters, and filtrate is condensed into and surveys relative density at 60-65 DEG C is the clear paste of 1.10-1.25;

3) by step 2) to add ethanol to making containing amount of alcohol be 60% for the clear paste that obtains, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%;

4) extractum that step 3) obtains is added sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization, packed products, makes oral liquid, to obtain final product.

Instructions of taking: every day is early, middle and late respectively takes once, and a dose is l5ml, 15 days courses for the treatment of, manyly after taking medicine took effect at 5 days, 1-3 the healing course for the treatment of.

Because of in Chinese medicine oral liquid of the present invention, have a few taste crude drug-nature and flavor to be virose, so obtained Chinese medicine oral liquid, whether to the poisonous pair of human body, therefore does following experiment:

Chinese medicine oral liquid toxicity test of the present invention: getting body weight is female and each 28 of the male white mouse of 12-20g, use Chinese medicine oral liquid gavage respectively, each 1 time of morning and afternoon, 300 times of behaviour dosage, Continuous Observation seven days, none is only dead, the no abnormality seens such as outward appearance, appetite and behavior, put to death zootomy perusal, the main organs such as the uterus of its heart, liver, spleen, lung, kidney, ovary are also without significant change.Show: Chinese medicine oral liquid experiment of the present invention, without obvious toxicity, does not cause each organ poison to become.

Its male and female are two organizes differential blood count all within normal range, no abnormality seen.As follows in Table:

beneficial effect

Chinese medicine oral liquid advantage of the present invention is:

(1) provide a kind of Chinese medicine oral liquid for the treatment of hyperuricemia, add clinical application kind, meet clinical needs.

(2) Chinese medicine oral liquid of the present invention effectively can reduce prevention metabolic arthritis pH value, reduce patient suffering, metabolic arthritis causes the related symptoms such as gout, hypertension, diabetes to have quick opsonic action, clinical verification shows Chinese medicine oral liquid Be very effective of the present invention, and curative effect that Chinese medicine oral liquid of the present invention reaches is that those of ordinary skill in the art are beyond thought.

(3) extract oral liquid preparing process of the present invention is simple, has determined curative effect, and composition is simple, and comprehensively regulating, reasonable recipe, between different batches medicine, mass discrepancy is little, and drug quality is uniform and stable.

Detailed description of the invention

embodiment 1

Raw material: Radix Aconiti Lateralis Preparata 10 parts, Radix Ampelopsis 5 parts, Rhizoma Chuanxiong 5 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 5 parts, Rhizoma Cimicifugae 5 parts, Radix Angelicae Pubescentis 15 parts, the Radix Astragali 5 parts, Rhizoma Smilacis Glabrae 10 parts, Flos Chrysanthemi 5 parts, Cortex Acanthopancis 10 parts, Radix Gentianae Macrophyllae 5 parts, Radix Saposhnikoviae 6 parts, black Rhizoma Zingiberis Recens 3 parts, Herba Schizonepetae 4 parts, Ziziphi Spinosae 5 parts, Folium Artemisiae Argyi 10 parts, 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 10 parts.

Preparation:

1) following weight parts proportioning raw material of Chinese medicine is taken: Radix Aconiti Lateralis Preparata 10 parts, Radix Ampelopsis 5 parts, Rhizoma Chuanxiong 5 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 5 parts, Rhizoma Cimicifugae 5 parts, Radix Angelicae Pubescentis 15 parts, the Radix Astragali 5 parts, Rhizoma Smilacis Glabrae 10 parts, Flos Chrysanthemi 5 parts, Cortex Acanthopancis 10 parts, Radix Gentianae Macrophyllae 5 parts, Radix Saposhnikoviae 6 parts, black Rhizoma Zingiberis Recens 3 parts, Herba Schizonepetae 4 parts, Ziziphi Spinosae 5 parts, Folium Artemisiae Argyi 10 parts, 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 10 parts;

2) above-mentioned raw material of Chinese medicine soak by water secondary, each water consumption is the 8-10 times amount of medical material weight, decocts secondary, each l-2 hour, filters, and filtrate is condensed into and surveys relative density at 60-65 DEG C is the clear paste of 1.10-1.25;

3) by step 2) to add ethanol to making containing amount of alcohol be 60% for the clear paste that obtains, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%;

4) extractum that step 3) obtains is added sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization, packed products, makes oral liquid, to obtain final product.

Instructions of taking: every day is early, middle and late respectively takes once, and a dose is l5ml, 15 days courses for the treatment of, manyly after taking medicine took effect at 5 days, 1-3 the healing course for the treatment of.

embodiment 2

Raw material: Radix Aconiti Lateralis Preparata 10kg, Radix Ampelopsis 6kg, Rhizoma Chuanxiong 6kg, Monetariamoneta (L.)(Monetariaannulus (L.)) 6kg, Rhizoma Cimicifugae 6kg, Radix Angelicae Pubescentis 15kg, Radix Astragali 5kg, Rhizoma Smilacis Glabrae 10kg, Flos Chrysanthemi 8kg, Cortex Acanthopancis 10kg, Radix Gentianae Macrophyllae 10kg, Radix Saposhnikoviae 8kg, black Rhizoma Zingiberis Recens 3kg, Herba Schizonepetae 4kg, Ziziphi Spinosae 10kg, Folium Artemisiae Argyi 8kg, Fructus Pruni pseudocerasi 10kg, Fructus Vitis viniferae 10kg.

Prepare identical with embodiment 1 with instructions of taking.

embodiment 3

Raw material: Radix Aconiti Lateralis Preparata 6kg, Radix Ampelopsis 3kg, Rhizoma Chuanxiong 3kg, Monetariamoneta (L.)(Monetariaannulus (L.)) 3kg, Rhizoma Cimicifugae 3kg, Radix Angelicae Pubescentis 10kg, Radix Astragali 3kg, Rhizoma Smilacis Glabrae 5kg, Flos Chrysanthemi 3kg, Cortex Acanthopancis 5kg, Radix Gentianae Macrophyllae 5kg, Radix Saposhnikoviae 3kg, black Rhizoma Zingiberis Recens 2kg, Herba Schizonepetae 2kg, Ziziphi Spinosae 3kg, Folium Artemisiae Argyi 3kg, Fructus Pruni pseudocerasi 5kg, Fructus Vitis viniferae 5kg.

Prepare identical with embodiment 1 with instructions of taking.

model case

Case 1 pond certain, women, 58 years old, patient main suit: violent lumbago appears suddenly in night, and has hematuria, through checking that to have made clear be the misfortune that renal calculus is invited.Composition through chemical examination discovery calculus is urate, and blood uric acid is also high.Since patient idiopathy, spirit, diet are normal, and sleep bad, stool, urine is normal, take Chinese medicine oral liquid of the present invention afterwards, within 15 days, lumbago disappears, and period urinates and do not occur hematuria, adhere to taking 2 courses for the treatment of again, current uric acid level is within normal range, and the health mental status is good.

Case 2 poplar, male, 45 years old, patient main suit: due to from little he live in coastal area, from sensible, annual summer seafood, medicated beer can't do without naturally, meal of almost eating is eaten.After work, be swamped with again and not free go home to have a meal, medicated beer, seafood have become his friend to have a dinner party, receive the usual way of affiliate especially.A night in summer before 5 years, when he received client sottish go home after, lie on a bed and prepare to sleep one when feeling greatly comfortablely, broken into a sweat to frightened as grieved pain as lancinating by left foot toe is a burst of suddenly, awake from a drunken sleep a greater part of.When getting up to check, find around left foot thumb joint and soft tissue occurs that large area is red and swollen, heating pain, even cover a very thin coverlet all extremely painful, around some vibration also can hurt like hell a little.After through examination in hospital, be that metabolic arthritis causes gout disease, take Chinese medicine oral liquid of the present invention afterwards, decline through hospital's check uric acid level after 15 days, left foot redness alleviates, and be clearly better phenomenon, adhere to taking 1 course for the treatment of, fully recover at present, visit of in recent years sending a telegram here has no recurrence.

Claims (3)

1. treat the Chinese medicine oral liquid of hyperuricemia for one kind, it is characterized in that, it is formulated by the raw material of Chinese medicine of following weight parts: Radix Aconiti Lateralis Preparata 6 ~ 10 parts, Radix Ampelopsis 3 ~ 6 parts, Rhizoma Chuanxiong 3 ~ 6 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 3 ~ 6 parts, Rhizoma Cimicifugae 3 ~ 6 parts, Radix Angelicae Pubescentis 10 ~ 18 parts, the Radix Astragali 3 ~ 5 parts, Rhizoma Smilacis Glabrae 5 ~ 10 parts, Flos Chrysanthemi 3 ~ 8 parts, Cortex Acanthopancis 5 ~ 10 parts, Radix Gentianae Macrophyllae 5 ~ 10 parts, Radix Saposhnikoviae 3 ~ 8 parts, black Rhizoma Zingiberis Recens 2 ~ 5 parts, Herba Schizonepetae 2 ~ 4 parts, Ziziphi Spinosae 3 ~ 6 parts, Folium Artemisiae Argyi 3 ~ 10 parts, 5 ~ 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 5 ~ 10 parts.

2. the Chinese medicine oral liquid for the treatment of hyperuricemia according to claim 1, it is characterized in that, it is formulated by the raw material of Chinese medicine of following weight parts: Radix Aconiti Lateralis Preparata 10 parts, Radix Ampelopsis 5 parts, Rhizoma Chuanxiong 5 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 5 parts, Rhizoma Cimicifugae 5 parts, Radix Angelicae Pubescentis 15 parts, the Radix Astragali 5 parts, Rhizoma Smilacis Glabrae 10 parts, Flos Chrysanthemi 5 parts, Cortex Acanthopancis 10 parts, Radix Gentianae Macrophyllae 5 parts, Radix Saposhnikoviae 6 parts, black Rhizoma Zingiberis Recens 3 parts, Herba Schizonepetae 4 parts, Ziziphi Spinosae 5 parts, Folium Artemisiae Argyi 10 parts, 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 10 parts.

3. the preparation method of the Chinese medicine oral liquid for the treatment of hyperuricemia according to claim 1, it is characterized in that, the method comprises the steps:

1) following weight parts proportioning raw material of Chinese medicine is taken: Radix Aconiti Lateralis Preparata 6 ~ 10 parts, Radix Ampelopsis 3 ~ 6 parts, Rhizoma Chuanxiong 3 ~ 6 parts, Monetariamoneta (L.)(Monetariaannulus (L.)) 3 ~ 6 parts, Rhizoma Cimicifugae 3 ~ 6 parts, Radix Angelicae Pubescentis 10 ~ 18 parts, the Radix Astragali 3 ~ 5 parts, Rhizoma Smilacis Glabrae 5 ~ 10 parts, Flos Chrysanthemi 3 ~ 8 parts, Cortex Acanthopancis 5 ~ 10 parts, Radix Gentianae Macrophyllae 5 ~ 10 parts, Radix Saposhnikoviae 3 ~ 8 parts, black Rhizoma Zingiberis Recens 2 ~ 5 parts, Herba Schizonepetae 2 ~ 4 parts, Ziziphi Spinosae 3 ~ 6 parts, Folium Artemisiae Argyi 3 ~ 10 parts, 5 ~ 10 parts, Fructus Pruni pseudocerasi, Fructus Vitis viniferae 5 ~ 10 parts;

2) above-mentioned raw material of Chinese medicine soak by water secondary, each water consumption is the 8-10 times amount of medical material weight, decocts secondary, each l-2 hour, filters, and filtrate is condensed into and surveys relative density at 60-65 DEG C is the clear paste of 1.10-1.25;

3) by step 2) to add ethanol to making containing amount of alcohol be 60% for the clear paste that obtains, stir evenly, leave standstill, filter, get filtrate recycling ethanol, be condensed into the extractum containing solid weight 65-67%;

4) extractum that step 3) obtains is added sucrose 20%, refined honey 12%, antiseptic 1-3%, stock solution embedding, irradiation sterilization, packed products, makes oral liquid, to obtain final product.