CN104984116A - Traditional Chinese medicine composition for treating kidney stone - Google Patents
Traditional Chinese medicine composition for treating kidney stone Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating kidney stone. The traditional Chinese medicine composition is prepared from the following active pharmaceutical ingredients in parts by weight: 15-25 parts of dianthus superbus, 15-25 parts of lalang grass rhizome, 10-15 parts of plantain seed, 10-15 parts of caulis milletiae, 10-15 parts of longhairy antenoron herb, 10-15 parts of rhizoma atractylodis, 5-10 parts of poria cocos, 5-10 parts of mongolian dandelion herb, 5-10 parts of mulberry, 5-10 parts of teasel root and 5-10 parts of edible tulip. The traditional Chinese medicine composition has the efficacies of eliminating stagnation to decompose stone, promoting the circulation of qi to remove stasis, clearing away heat and toxic materials, and relieving stranguria by dieresis; clinical application shows that the traditional Chinese medicine composition has an obvious effect of treating kidney stone, and is convenient to take and free of side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, in particular to a kind of Chinese medicine composition for the treatment of renal calculus.
Background technology
Renal calculus is worldwide common frdquently encountered disease, is also a kind of serious disease affecting human health.In recent years, because living standards of the people improve, its sickness rate also significantly improves.The clinical manifestation of renal calculus is mainly renal colic, hematuria, can cause urinary tract obstruction or urinary tract infection.Renal calculus is a kind of disease affected by multiple extraneous factor, relevant with geographical environments such as regional water quality, temperature, height above sea level; Relevant with the sex of patient, inherited genetic factors; And diet structure, living habit are also considered to possible key factor.
Calcium oxalate is one of main component of lithangiuria.In China, with calcium oxalate be relapse rate after the calculus of main component is cured up to 60 ~ 80%, and quite a few disease is because of unclear, and its Forming Mechanism is illustrated not yet completely.
The Western medicine medicine being used for the treatment of renal calculus is less, often based on symptomatic treatment.Though had extracorporeal shock-wave lithotomy and some non-open operations to get the minimally-invasive treatment application such as stone in recent years, make much formerly to need the patient of operative treatment to decrease wound, eliminate operation painful, the cooperation of medicine but the calculus after its rubble and prevention recurrence of hepatolithiasis are still needed, its treatment can only take stopgap measures, and is difficult to reach the object of effecting a permanent cure.And extracorporeal shock-wave lithotomy therapy has certain indication, also there is certain damage to kidney.
Motherland's traditional medical theory is thought, lithangiuria belongs to the sick category such as the traditional Chinese medical science " stranguria dne to urolithiasis ", " hematuria ", " lumbago ", " deficient " and " obstruction and rejection ".About the etiology and pathogenesis of stranguria caused by urinary stone, before the Tang Dynasty, motherland's medical science, under the guidance of "Nei Jing" theory, just has more complete understanding.Especially it should be noted that Chinese Huatuo " Huatuo's Zhongzang classic " records: " sand Stranguria person, this is by deficiency of kidney-QI ... void hinders vital qi, pathogenic heat crescendo; knot is poly-forms sand, and and for example with decocting in water salt, fiery flood is few; salt is Cheng Shi and so on gradually, lid kidney person, and water also; become to be attributed to kidney; saltyly amass in kidney, water stay under, deficiency-heat day is very; decoct knot and give birth to, the work in non-a period of time is also again ".Sui's Chao Yuanfang (550-630 A.D.) " General Treatise on the Cause and Symptoms of Diseases " carries: " the main water of kidney, water knot then turns to stone, therefore kidney visitor sandstone, skin is empty to be taken advantage of by hot, and heat then becomes to drench ".Think that sand Stranguria decocts water by pathogenic heat of suffering from a deficiency of the kidney to form, the work in non-a period of time.And " alkali amasss in kidney ", " kidney visitor sandstone " indicate that stone location is at kidney." all pouring send out, all suffer from a deficiency of the kidney bladder heat-dissipating also " is thought by unit's Zhu Zhenheng " danxi's experiential therapy ".Clear Li Zhongzi " Required Readings for Medical Professionals " thinks, and " stranguria caused by urinary stone person, just like sandstone, bladder accumulation of heat forms.As soup bottle for a long time in water, the white alkali of bear building-up also ".In a word the morbidity of ancient Chinese medicine doctor to " sand Stranguria ", " stranguria caused by urinary stone " think mainly due to suffer from a deficiency of the kidney and part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels heat cause, sick position is at kidney or at bladder or at excessive key, and void is intrinsic factor.Exterior and interior relation between kidney and bladder, the power of functioning of bladder, from kidney, is suffered from a deficiency of the kidney, and cause functioning of bladder unfavorable, urinary function is not normal, is conducive to the formation of calculus.Multiple because of the damp and hot accumulation part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, damp and hot can by being invaded by exogenous pathogen, also can be caused by polyphagia delicious food, urine is decocted by it, and in urine, impurity then forms sandstone.Little person becomes sand to be " sand Stranguria ", large person Cheng Shiwei " stranguria caused by urinary stone ", injury of blood collaterals by heat, and the absurd row of forcing blood then blood underflow, occurs hematuria and be " stranguria with blood ".
The traditional Chinese medical science mainly carries out determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs according to clinical syndrome for the treatment of upper urinary stone, its rule for the treatment of based on Tonglin Paishi, in conjunction with tongue arteries and veins, symptom assistant with heat clearing away, regulate the flow of vital energy, invigorate blood circulation, the method such as YIN nourishing, QI invigorating and the kidney warming, thus treating both the principal and secondary aspects of a disease is carried out to urinary calculus.Therefore, Chinese medicine calculus is with the advantage of its uniqueness, and treatment upper urinary stone can improve nature lithagogue rate, reduces operability, improves hydronephrosis, renal function, and part Chinese medicine solubilized oxalate calculus also can prevent the recurrence of oxalate calculus.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of renal calculus, based on the dialectical prescription of tcm theory, there is effect of eliminating stagnation fossil, circulation of qi promoting blood stasis dispelling, heat-clearing and toxic substances removing, relieving stranguria by diuresis, clinical practice shows, this traditional Chinese medicine composition for treating renal calculus successful, taking convenience, has no side effect.
Concrete, one aspect of the present invention provides a kind of Chinese medicine composition for the treatment of renal calculus, is made up of the crude drug of following weight portion: Herba Dianthi 15-25 part, Rhizoma Imperatae 15-25 part.
In a specific embodiment of the present invention, described a kind of Chinese medicine composition for the treatment of renal calculus, is made up of the crude drug of following weight portion: Herba Dianthi 15-25 part, Rhizoma Imperatae 15-25 part, Semen Plantaginis 10-15 part, Caulis Spatholobi 10-15 part, Herba Lysimachiae 10-15 part, Rhizoma Atractylodis 10-15 part, Poria 5-10 part, Herba Taraxaci 5-10 part, Fructus Mori 5-10 part, Radix Dipsaci 5-10 part, Pseudobulbus Cremastrae Seu Pleiones 5-10 part.
In a specific embodiment of the present invention, described a kind of Chinese medicine composition for the treatment of renal calculus, is made up of the crude drug of following weight portion: Herba Dianthi 15 parts, Rhizoma Imperatae 15 parts, Semen Plantaginis 10 parts, Caulis Spatholobi 10 parts, Herba Lysimachiae 10 parts, Rhizoma Atractylodis 10 parts, 5 parts, Poria, Herba Taraxaci 5 parts, 5 parts, Fructus Mori, Radix Dipsaci 5 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts.
In a specific embodiment of the present invention, described a kind of Chinese medicine composition for the treatment of renal calculus, is made up of the crude drug of following weight portion: Herba Dianthi 25 parts, Rhizoma Imperatae 25 parts, Semen Plantaginis 15 parts, Caulis Spatholobi 15 parts, Herba Lysimachiae 15 parts, Rhizoma Atractylodis 15 parts, 10 parts, Poria, Herba Taraxaci 10 parts, 10 parts, Fructus Mori, Radix Dipsaci 10 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts.
In a specific embodiment of the present invention, described a kind of Chinese medicine composition for the treatment of renal calculus, is made up of the crude drug of following weight portion: Herba Dianthi 15 parts, Rhizoma Imperatae 25 parts, Semen Plantaginis 10 parts, Caulis Spatholobi 15 parts, Herba Lysimachiae 10 parts, Rhizoma Atractylodis 15 parts, 5 parts, Poria, Herba Taraxaci 10 parts, 5 parts, Fructus Mori, Radix Dipsaci 10 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts.
The present invention provides a kind of preparation method for the treatment of the Chinese medicine composition of renal calculus on the other hand, comprises the following steps:
(1) Herba Dianthi, Rhizoma Imperatae, Herba Lysimachiae, Rhizoma Atractylodis, Pseudobulbus Cremastrae Seu Pleiones are added soak by water 2-3 time accounting for gross weight 8-15 times amount, each 1.5-2 hour, collects medicinal residues for subsequent use, collecting decoction, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) medicinal residues in Semen Plantaginis, Caulis Spatholobi, Poria, Herba Taraxaci, Fructus Mori, Radix Dipsaci and step (1) are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 2-3 time, each 2-3 hour, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, to obtain final product.
In a specific embodiment of the present invention, wherein add the soak by water 3 times accounting for gross weight 10 times amount in step (1), each 1.5 hours; Account in step (2) in the alcoholic solution of 85% of gross weight 10 times amount and extract 2 times, each 3 hours.
Pharmaceutical composition of the present invention can also be prepared according to the conventional method of the field of Chinese medicines, comprises soak by water etc.The Chinese medicine composition for the treatment of renal calculus of the present invention, adopts the conventional method of Chinese medicine preparation to be prepared into any traditional oral preparation.Described oral formulations is capsule, pill, powder, tablet, granule.
The Chinese medicine composition for the treatment of renal calculus of the present invention, based on the dialectical prescription of tcm theory, has effect of eliminating stagnation fossil, circulation of qi promoting blood stasis dispelling, heat-clearing and toxic substances removing, relieving stranguria by diuresis, clinical practice shows, this traditional Chinese medicine composition for treating renal calculus successful, taking convenience, has no side effect.
Detailed description of the invention
Embodiment 1:
Treat a Chinese medicine composition for renal calculus, be made up of the crude drug of following weight portion: Herba Dianthi 15g, Rhizoma Imperatae 15g, Semen Plantaginis 10g, Caulis Spatholobi 10g, Herba Lysimachiae 10g, Rhizoma Atractylodis 10g, Poria 5g, Herba Taraxaci 5g, Fructus Mori 5g, Radix Dipsaci 5g, Pseudobulbus Cremastrae Seu Pleiones 5g;
Take said medicine by formula ratio, be added to the water, boil, slow fire boiling 30 minutes, filter, filtering residue adds water again, slow fire boiling 30 minutes, merge twice medicinal liquid, to obtain final product.
Embodiment 2:
Treat a Chinese medicine composition for renal calculus, be made up of the crude drug of following weight portion: Herba Dianthi 15g, Rhizoma Imperatae 15g, Semen Plantaginis 10g, Caulis Spatholobi 10g, Herba Lysimachiae 10g, Rhizoma Atractylodis 10g, Poria 5g, Herba Taraxaci 5g, Fructus Mori 5g, Radix Dipsaci 5g, Pseudobulbus Cremastrae Seu Pleiones 5g;
Preparation method comprises the following steps:
(1) Herba Dianthi, Rhizoma Imperatae, Herba Lysimachiae, Rhizoma Atractylodis, Pseudobulbus Cremastrae Seu Pleiones are added the soak by water 3 times accounting for gross weight 8 times amount, each 1.5 hours, collect medicinal residues for subsequent use, collecting decoction, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) medicinal residues in Semen Plantaginis, Caulis Spatholobi, Poria, Herba Taraxaci, Fructus Mori, Radix Dipsaci and step (1) are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 2 times, each 3 hours, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, to obtain final product.
Embodiment 3:
Treat a Chinese medicine composition for renal calculus, be made up of the crude drug of following weight portion: Herba Dianthi 25g, Rhizoma Imperatae 25g, Semen Plantaginis 15g, Caulis Spatholobi 15g, Herba Lysimachiae 15g, Rhizoma Atractylodis 15g, Poria 10g, Herba Taraxaci 10g, Fructus Mori 10g, Radix Dipsaci 10g, Pseudobulbus Cremastrae Seu Pleiones 10g;
Preparation method comprises the following steps:
(1) Herba Dianthi, Rhizoma Imperatae, Herba Lysimachiae, Rhizoma Atractylodis, Pseudobulbus Cremastrae Seu Pleiones are added the soak by water 2 times accounting for gross weight 15 times amount, each 1.5 hours, collect medicinal residues for subsequent use, collecting decoction, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) medicinal residues in Semen Plantaginis, Caulis Spatholobi, Poria, Herba Taraxaci, Fructus Mori, Radix Dipsaci and step (1) are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 3 times, each 2 hours, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, to obtain final product.
Embodiment 4:
Treat a Chinese medicine composition for renal calculus, be made up of the crude drug of following weight portion: Herba Dianthi 15g, Rhizoma Imperatae 25g, Semen Plantaginis 10g, Caulis Spatholobi 15g, Herba Lysimachiae 10g, Rhizoma Atractylodis 15g, Poria 5g, Herba Taraxaci 10g, Fructus Mori 5g, Radix Dipsaci 10g, Pseudobulbus Cremastrae Seu Pleiones 5g;
Preparation method comprises the following steps:
(1) Herba Dianthi, Rhizoma Imperatae, Herba Lysimachiae, Rhizoma Atractylodis, Pseudobulbus Cremastrae Seu Pleiones are added the soak by water 2 times accounting for gross weight 15 times amount, each 2 hours, collect medicinal residues for subsequent use, collecting decoction, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) medicinal residues in Semen Plantaginis, Caulis Spatholobi, Poria, Herba Taraxaci, Fructus Mori, Radix Dipsaci and step (1) are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 2 times, each 3 hours, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, to obtain final product.
Embodiment 4: clinical data
1, physical data
Clinically choose renal calculus patient 200 example, above-mentioned case all master states lumbago in various degree, or typical renal colic and hematuria, all makes a definite diagnosis through ultrasound diagnosis.
2, usage and dosage: during clinical practice, the amounts of components in compositions takes the circumstances into consideration increase and decrease according to the body weight of patient and age.One day potion, decocting twice extracting juice is about 300ml, and point morning, evening take for twice.It within one month, is a course for the treatment of.Advise patient's great quantity of water drinking, and do more jog, squat down, the activity such as jump, move down discharge in order to calculus.
3, curative effect judging standard
With reference to the curative effect judging standard of stranguria caused by urinary stone in " Chinese medical disease Standardization of diagnosis and curative effect ", effective finger subjective symptoms such as patient's waist and belly dull pain after treatment disappears completely, and urine examination recovers normal, and check urinary system B ultrasonic has no calculus, hydrops; Effective finger patient urine examination is normal, and check urinary system B ultrasonic display renal calculus is narrow by the 1st, and has been down into proximal ureteral, or former multiple calculus has the discharge of part calculus; Invalid finger patient's subjective symptoms and the check of urinary system B ultrasonic are all without improvement, and renal calculus position is without movement, and hydronephrosis even increases the weight of without improvement.
4, therapeutic outcome:
Result after 3 courses for the treatment of: effective 102 examples, effective 81 examples, invalid 17 examples, total effective rate 91.5%.
Model case:
Mrs Liu, 57 years old, suffers from renal calculus 10 years, kidney portion is slight hydrops, and the conscious pain in the lumbar region soreness of waist is tired, through repeatedly external stone crushing operation, does not all thoroughly cure.Take Chinese medicine composition of the present invention after 2 months, conscious pain symptom obviously alleviates, and continue again to take 2 months, symptom all disappears, and all gets rid of through ultrasound diagnosis display calculus; Follow up a case by regular visits to 1 year without recurrence.
, 51 years old, there is the left lumbar region angor without obvious inducement, spontaneous remission after a few hours in Mr. Li, ultrasound diagnosis finds left side renal calculus, gives remission after medicine lithagogue treatment before 1 year, rear about outbreak in 6 months once; Take Chinese medicine composition of the present invention 1 month, symptom obviously alleviates, and continue to take 1 month, symptom all disappears, and B ultrasonic display left side renal calculus disappears; Follow up a case by regular visits to 1 year without recurrence.
Mrs An, 45 years old, occurred right side waist and belly paroxysmal pain without obvious inducement before 6 months and occur hematuria, B ultrasonic showed right Renal sinus separation, and right ureter epimere is obviously expanded, and has calculus to pile up in middle hypomere.Take Chinese medicine composition of the present invention after 1 month, pain symptom all disappears, and B ultrasonic display calculus all disappears, and continues to take 2 months, recurrence that so far there are no.
Claims (9)
1. treat a Chinese medicine composition for renal calculus, it is characterized in that, be made up of the crude drug of following weight portion: Herba Dianthi 15-25 part, Rhizoma Imperatae 15-25 part.
2. a kind of Chinese medicine composition for the treatment of renal calculus according to claim 1, be made up of the crude drug of following weight portion: Herba Dianthi 15-25 part, Rhizoma Imperatae 15-25 part, Semen Plantaginis 10-15 part, Caulis Spatholobi 10-15 part, Herba Lysimachiae 10-15 part, Rhizoma Atractylodis 10-15 part, Poria 5-10 part, Herba Taraxaci 5-10 part, Fructus Mori 5-10 part, Radix Dipsaci 5-10 part, Pseudobulbus Cremastrae Seu Pleiones 5-10 part.
3. a kind of Chinese medicine composition for the treatment of renal calculus according to claim 1, is made up of the crude drug of following weight portion: Herba Dianthi 15 parts, Rhizoma Imperatae 15 parts, Semen Plantaginis 10 parts, Caulis Spatholobi 10 parts, Herba Lysimachiae 10 parts, Rhizoma Atractylodis 10 parts, 5 parts, Poria, Herba Taraxaci 5 parts, 5 parts, Fructus Mori, Radix Dipsaci 5 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts.
4. a kind of Chinese medicine composition for the treatment of renal calculus according to claim 1, be made up of the crude drug of following weight portion: Herba Dianthi 25 parts, Rhizoma Imperatae 25 parts, Semen Plantaginis 15 parts, Caulis Spatholobi 15 parts, Herba Lysimachiae 15 parts, Rhizoma Atractylodis 15 parts, 10 parts, Poria, Herba Taraxaci 10 parts, 10 parts, Fructus Mori, Radix Dipsaci 10 parts, Pseudobulbus Cremastrae Seu Pleiones 10 parts.
5. a kind of Chinese medicine composition for the treatment of renal calculus according to claim 1, is made up of the crude drug of following weight portion: Herba Dianthi 15 parts, Rhizoma Imperatae 25 parts, Semen Plantaginis 10 parts, Caulis Spatholobi 15 parts, Herba Lysimachiae 10 parts, Rhizoma Atractylodis 15 parts, 5 parts, Poria, Herba Taraxaci 10 parts, 5 parts, Fructus Mori, Radix Dipsaci 10 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts.
6. a kind of preparation method for the treatment of the Chinese medicine composition of renal calculus described in claim 2-5, is characterized in that, comprise the following steps:
(1) Herba Dianthi, Rhizoma Imperatae, Herba Lysimachiae, Rhizoma Atractylodis, Pseudobulbus Cremastrae Seu Pleiones are added soak by water 2-3 time accounting for gross weight 8-15 times amount, each 1.5-2 hour, collects medicinal residues for subsequent use, collecting decoction, filter, relative density when filtrate is concentrated into 80 DEG C is the extractum (I) of 1.15-1.25;
(2) medicinal residues in Semen Plantaginis, Caulis Spatholobi, Poria, Herba Taraxaci, Fructus Mori, Radix Dipsaci and step (1) are added account for gross weight 8-15 times amount 85% alcoholic solution in extract 2-3 time, each 2-3 hour, filter, merging filtrate, placement is spent the night, reclaim ethanol, relative density when filtrate being concentrated into 60 DEG C is the extractum (II) of 1.15-1.25;
(3) in step (1), the mixing of (2) gained extractum, to obtain final product.
7. preparation method according to claim 6, wherein adds the soak by water 3 times accounting for gross weight 10 times amount, each 1.5 hours in step (1); Account in step (2) in the alcoholic solution of 85% of gross weight 10 times amount and extract 2 times, each 3 hours.
8. the Chinese medicine composition of the treatment renal calculus described in claim 1-5, is characterized in that, adopts the conventional method of Chinese medicine preparation to be prepared into any traditional oral preparation.
9. the Chinese medicine composition for the treatment of renal calculus according to claim 8, is characterized in that, described oral formulations is oral liquid, capsule, pill, powder, tablet, granule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107715027A (en) * | 2017-11-22 | 2018-02-23 | 宋志芳 | Treat the Chinese medicine composition of kidney stone |
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|---|---|---|---|---|
| CN1300609A (en) * | 2000-12-25 | 2001-06-27 | 郑阿权 | Medicine for treating calculus in urinary system |
| CN1720945A (en) * | 2005-06-28 | 2006-01-18 | 郑阿权 | Medicine for treating calculus in urinary system |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1300609A (en) * | 2000-12-25 | 2001-06-27 | 郑阿权 | Medicine for treating calculus in urinary system |
| CN1720945A (en) * | 2005-06-28 | 2006-01-18 | 郑阿权 | Medicine for treating calculus in urinary system |
Non-Patent Citations (1)
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| 李方玲: "《肾病临床常用中药指南》", 30 November 2005 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107715027A (en) * | 2017-11-22 | 2018-02-23 | 宋志芳 | Treat the Chinese medicine composition of kidney stone |
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Application publication date: 20151021 |