CN107715027A - Treat the Chinese medicine composition of kidney stone - Google Patents

Treat the Chinese medicine composition of kidney stone Download PDF

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CN107715027A
CN107715027A CN201711171082.6A CN201711171082A CN107715027A CN 107715027 A CN107715027 A CN 107715027A CN 201711171082 A CN201711171082 A CN 201711171082A CN 107715027 A CN107715027 A CN 107715027A
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stone
kidney stone
chinese medicine
root
medicine composition
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宋志芳
于娟
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A61K36/12—Filicopsida or Pteridopsida
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The present invention relates to a kind of pharmaceutical formulation field, specifically a kind of Chinese medicine composition for treating kidney stone, it is characterised in that be made up by weight percentage of the following raw material medicine：Stone reed 7~10%, raspberry 4~6%, rhizoma imperatae 8~11%, rhizoma homalonemae 7~10%, fructus viticis 9~12%, rubble grass 6~9%, the tuber of stemona 2~5%, phoenix-tail fern 3~5%, Morinda officinalis 2~5%, paniculate swallowwort 4~7%, pivot store 2~6%, cordate houttuynia 2~5%, Semen Cuscutae 3~6%, the Radix Astragali 2~4%, sword-like iris root 2~4%, Fructus meliae toosendan 2~5%, cudrania root 3~5%, hairyvein agrimony 3~5%, Yun Ling 4~6%, add decocting to be removed slag after enduring to obtain filtrate above-mentioned raw materials medicine.The present invention has the effect of anti-inflammatory analgetic, promoting blood circulation and removing blood stasis, promoting the circulation of qi dissipating bind, diuresis and stone expeling, suitable for there is waist to ache, the kidney stone patient of the symptom such as weak, the not smooth, blood urine of urination in the whole body.

Description

Treat the Chinese medicine composition of kidney stone
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine composition for being used to treat kidney stone.
Background technology
It is a kind of common disease of urinary system it is well known that kidney stone, its Symptoms：When calculus moves with urine Lumbago, or blood urine can be influenceed, frequent micturition, odynuria, urination is not smooth, and severe patient can occur anuria, renal failure, Poisoning and stop Gram.At present, the medicine of clinical treatment kidney stone is more, but because the structure of kidney is special, the effect and medicine of drug therapy Fossil dissolve stone function it is not satisfactory, most patients are not able to and are transferred to operative treatment；And operative treatment is often with medicine mistake Quick to wait side effect, postoperative easily recurrence, financial expenditure is big, and wound is big, treatment time length, serious economy and body is brought to sufferer Burden.
The content of the invention
The technical problems to be solved by the invention are for overcome the deficiencies in the prior art, there is provided a kind of kidney stone for the treatment of Chinese medicine composition, it is evident in efficacy, have no toxic side effect, cost is cheap.
The present invention solves the technical scheme that above-mentioned technical problem uses：A kind of Chinese medicine composition for treating kidney stone, its It is characterised by, is made up by weight percentage of the following raw material medicine：Stone reed 7~10%, raspberry 4~6%, rhizoma imperatae 8~11%, Rhizoma homalonemae 7~10%, fructus viticis 9~12%, rubble grass 6~9%, the tuber of stemona 2~5%, phoenix-tail fern 3~5%, Morinda officinalis 2~5%, Xu are long The, pivots of minister in ancient times 4~7% store 2~6%, cordate houttuynia 2~5%, Semen Cuscutae 3~6%, the Radix Astragali 2~4%, sword-like iris root 2~4%, Fructus meliae toosendan 2~5%, Cudrania root 3~5%, hairyvein agrimony 3~5%, Yun Ling 4~6%, decocting is added to be removed slag after enduring to obtain filtrate above-mentioned raw materials medicine.
The invention has the advantages that the effect of with anti-inflammatory analgetic, promoting blood circulation and removing blood stasis, promoting the circulation of qi dissipating bind, diuresis and stone expeling, be applicable In there is waist to ache, the whole body is weak, the kidney stone patient of the symptom such as the not smooth, blood urine of urination.
Embodiment
With reference to embodiment, the invention will be further described：
Embodiment 1：
Using stone reed, raspberry, rhizoma imperatae, rhizoma homalonemae, fructus viticis, rubble grass, the tuber of stemona, phoenix-tail fern, Morinda officinalis, paniculate swallowwort, pivots Storage, cordate houttuynia, Semen Cuscutae, the Radix Astragali, sword-like iris root, Fructus meliae toosendan, cudrania root, hairyvein agrimony, Yun Ling are made for raw material.Its component（Weight Measure %）Per secondary for stone reed 9.1, raspberry 4.6, rhizoma imperatae 10.1, rhizoma homalonemae 9.2, fructus viticis 10.8, rubble grass 8.1, the tuber of stemona 3.2nd, phoenix-tail fern 3.8, Morinda officinalis 3.2, the, pivots of paniculate swallowwort 5.9 store 3.9, cordate houttuynia 4.1, Semen Cuscutae 5.1, the Radix Astragali 3.1, sword-like iris root 2.0th, Fructus meliae toosendan 2.9, cudrania root 3.1, hairyvein agrimony 3.4, Yun Ling 4.4.19 200 grams of taste Chinese herbal medicine gross weights are taken, add water 1000ml Soak, decoct to obtain 300ml concoctions.It is daily 1 dose point 2 times it is oral, warmly take 150ml on an empty stomach every time.5 days as one therapeutic course, interval 2 My god, then next course for the treatment of is carried out, typically take 3 to 5 courses for the treatment of.
Stone reed of the present invention possesses promoting diuresis for stranguria, and clearing lung-heat expels the heat-evil and other effects.Available for leaching pain, hematuria, lithangiuria, ephritis； Raspberry has supplementing the kidney to control the nocturnal contracting urine, the effect of nourishing the liver to improve visual acuity；Rhizoma imperatae cooling blood and hemostasis, reducing fever and causing diuresis；Rhizoma homalonemae has wind-damp dispelling, The effect of strengthening the bone；Fructus viticis dispelling wind and heat from the body, head clearing, joint at dehumidifying；Rubble grass promoting qi circulation and relieving pain, food digesting stomach fortifying, stop dysentery, Invigorating spleen to remove dampness, dissipate the stasis of blood；Stemona root cough relieving resolving sputum, gentle lung qi, inducing diaphoresis of radiating；Phoenix-tail fern has clearing heat and promoting diuresis, cooling blood and hemostasis, detumescence Removing toxic substances and other effects；Morinda officinalis cures mainly impotence and seminal emission, uterus cold infertile, irregular menstruation, few abdomen crymodynia, arthralgia pain due to rheumatism, muscles and bones impotence；Slowly Long minister in ancient times's wind-expelling pain-stopping, removing toxicity for detumescence, warming and activating meridian；Pivot stores inducing diuresis for treating strangurtia, and desinsection is antipruritic；Cordate houttuynia have antibacterial, it is antiviral, Improve the effect such as immunity of organisms, diuresis；Semen Cuscutae is used for lumbago due to the kidney deficiency, impotence and seminal emission, frequent micturition, uterus cold infertile, the dark loose stool of mesh Kidney yin yang deficiency syndrome；The Radix Astragali has enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide anti- Bacterium acts on；Chinese small iris effects a radical cure larynx numbness, ulcer, arthralgia pain due to rheumatism；Fructus meliae toosendan is soothing the liver to expel the heat-evil, promoting qi circulation and relieving pain, desinsection；Cudrania root cough-relieving Phlegm, expelling wind and removing dampness, blood stasis removing analgesic；Hairyvein agrimony astringing to arrest bleeding, preventing malaria, stop dysentery, removing toxic substances；Cloud Siberian cocklebur clearing damp and promoting diuresis, invigorating the spleen, calming heart.19 Taste bulk drug collective effect, there is the effect of anti-inflammatory analgetic, promoting blood circulation and removing blood stasis, promoting the circulation of qi dissipating bind, diuresis and stone expeling, it is sour suitable for there is waist Bitterly, the kidney stone patient of the symptom such as weak, not smooth, blood urine of urination in the whole body, and it is evident in efficacy, have no toxic side effect, cost is cheap；Match somebody with somebody 5 is rigorous, has supplement kidney qi, increases the gasification function of bladder, promote urinary function normal, produces dissolve stone, arranges the effect of stone, And it is safe, be advantageous to patient and mitigate pain symptom in time.
Each raw material of the present invention can also ratio listed by according to the form below（Percentage by weight）The embodiment of mixing is realized.It processes work Skill is same as Example 1.
It is real Apply Example Stone Reed Cover Basin Son In vain Thatch Root Thousand Year It is strong It is climing Chaste tree Son It is broken Stone Grass Hundred Portion Phoenix Tail Grass Bar Halberd My god Slowly It is long Minister in ancient times Pivot Store Fish Raw meat Grass Tu Silk Son It is yellow Stilbene Horse Lin Root River Chinaberry Son Wear It is broken Stone It is celestial Crane Grass Yun Ling
Two 7 6 8 10 9 9 4 5 2 7 2 5 3 4 2 5 3 5 4
Three 10 4 8 7 12 6 5 3 5 4 6 2 6 2 4 2 5 3 6
Four 8 5 11 7 9 9 2 4 3 5 5 5 5 3 3 3 4 4 5
The invention will be further described for the clinical test carried out with reference to our hospital：
Case selection：100 clinical observations of kidney stone patient made a definite diagnosis are selected, patient is randomly divided into treatment group and control group two Group, treatment group 50,26~63 years old age, the course of disease most short person 1 month, most elder 3 years.Control group 50,28~60 years old age, The course of disease most short person 2 months, most elder 4 years.
Diagnostic criteria：Lumbago, blood urine, frequent micturition, odynuria, urination it is not smooth, severe patient can occur anuria, renal failure, Toxic shock.
Treatment method：It is daily 1 dose point 2 times it is oral, warmly take 150ml on an empty stomach every time.5 days as one therapeutic course, interval 2 days, Next course for the treatment of is carried out again, takes 5 courses for the treatment of.Control group takes allopurinol tablet, orally, one time 1~3,2~3 times on the one, before meals Taken after being chewed when half an hour or stomachache attack.
Efficacy determination：
（1）Cure：B ultrasound shows that kidney stone is discharged, internal noresidue, and graft function is normal.
（2）It is effective：B ultrasound shows that kidney stone reduces, and renal function is obviously improved.
（3）Effectively：B ultrasound shows that kidney stone has reduced, and renal function improves or without continuing to deteriorate.
（4）It is invalid：Symptom, sign are without improvement, and renal function is without improvement.
As a result：From in the treatment group of Chinese medicine preparation of the present invention, 22 are cured, effective 20, effective 16, invalid 2, Total effective rate 96%.
Healing 11 in control group, effective 6, effective 5, invalid 28, total effective rate 44%.
Result above shows, the cure rate and total effective rate for the treatment of group are apparently higher than control group.
Model case：
Sun, man, 41 years old, through ultrasound diagnosis, renal plevis had 2,4*5 millimeters calculus.Take two courses for the treatment of of Chinese medicine of the present invention Frequency symptoms take a turn for the better, and have calculus particle to be discharged with urine after taking three courses for the treatment of, one course for the treatment of of continual cure, and all diseases disappear, not Recurrence.
Perhaps so-and-so, female, 51 years old, kidney stone is diagnosed as through ultrasound diagnosis, and taking two courses for the treatment of of Chinese medicine of the present invention has calculus particle Discharged with urine, take three courses for the treatment of, symptom disappears, and physical recovery is normal.

Claims (1)

1. a kind of Chinese medicine composition for treating kidney stone, it is characterised in that be made up by weight percentage of the following raw material medicine：Stone Reed 7~10%, raspberry 4~6%, rhizoma imperatae 8~11%, rhizoma homalonemae 7~10%, fructus viticis 9~12%, rubble grass 6~9%, the tuber of stemona 2 ~5%, phoenix-tail fern 3~5%, Morinda officinalis 2~5%, the, pivots of paniculate swallowwort 4~7% store 2~6%, cordate houttuynia 2~5%, Semen Cuscutae 3~6%, Huang Stilbene 2~4%, sword-like iris root 2~4%, Fructus meliae toosendan 2~5%, cudrania root 3~5%, hairyvein agrimony 3~5%, Yun Ling 4~6%, by above-mentioned raw materials Medicine adds decocting to be removed slag after enduring to obtain filtrate.
CN201711171082.6A 2017-11-22 2017-11-22 Treat the Chinese medicine composition of kidney stone Pending CN107715027A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102861288A (en) * 2012-09-04 2013-01-09 刘长灵 Traditional Chinese medicine composite for treating kidney stone
CN103655978A (en) * 2013-12-18 2014-03-26 青岛百瑞吉生物工程有限公司 Traditional Chinese medicine formula composition capable of removing kidney stone and preparation method of composition
CN104984116A (en) * 2015-06-30 2015-10-21 翁博文 Traditional Chinese medicine composition for treating kidney stone

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102861288A (en) * 2012-09-04 2013-01-09 刘长灵 Traditional Chinese medicine composite for treating kidney stone
CN103655978A (en) * 2013-12-18 2014-03-26 青岛百瑞吉生物工程有限公司 Traditional Chinese medicine formula composition capable of removing kidney stone and preparation method of composition
CN104984116A (en) * 2015-06-30 2015-10-21 翁博文 Traditional Chinese medicine composition for treating kidney stone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
常成荣: "益肾解毒汤配合血液透析治疗慢性肾功能衰竭99例", 《陕西中医》 *
陈宏伟 等: "中西医结合治疗泌尿系结石60例疗效观察", 《新中医》 *

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Application publication date: 20180223